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Cheap flights from Manchester to Panama from £526

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/7. Fares are subject to change and may not be available on all flights or dates of travel.
MAN — PTY
9 Jul — 16 Jul1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Manchester to Panama

Enter your travel dates to find the best prices.

Cheapest flights from Manchester to Panama
Explore the most affordable flight options available from Manchester to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 9 June 2026.

Sun 1/1109:30
MAN
-
PTY
2 stops34h 15m
United Airlines
Sat 12/1210:00
PTY
-
MAN
2 stops26h 00m
United Airlines
Deal found 9/6£690
Mon 28/1206:10
MAN
-
PTY
2 stops28h 00m
United Airlines
Thu 14/110:00
PTY
-
MAN
2 stops19h 20m
United Airlines
Deal found 8/6£692
Wed 2/1209:30
MAN
-
PTY
2 stops36h 37m
United Airlines
Wed 9/1208:55
PTY
-
MAN
2 stops27h 05m
United Airlines
Deal found 5/6£695
Wed 8/706:05
MAN
-
PTY
2 stops27h 59m
United Airlines
Tue 14/722:55
PTY
-
MAN
2 stops28h 55m
United Airlines
Deal found 8/6£699
Fri 23/1006:05
MAN
-
PTY
2 stops19h 26m
United Airlines
Sat 21/1110:00
PTY
-
MAN
2 stops26h 00m
United Airlines
Deal found 7/6£700
Mon 26/1010:30
MAN
-
PTY
2 stops37h 32m
United Airlines
Mon 23/1116:41
PTY
-
MAN
2 stops43h 19m
United Airlines
Deal found 7/6£701
Mon 3/806:05
MAN
-
PTY
2 stops27h 59m
United Airlines
Mon 31/815:30
PTY
-
MAN
2 stops33h 00m
United Airlines
Deal found 8/6£702
Fri 3/706:05
MAN
-
PTY
2 stops27h 59m
United Airlines
Thu 9/722:55
PTY
-
MAN
2 stops28h 55m
United Airlines
Deal found 6/6£702
Thu 2/706:05
MAN
-
PTY
2 stops27h 59m
United Airlines
Thu 16/722:55
PTY
-
MAN
2 stops28h 55m
United Airlines
Deal found 5/6£704
Thu 22/1006:05
MAN
-
PTY
2 stops19h 26m
United Airlines
Thu 29/1015:41
PTY
-
MAN
2 stops44h 19m
United Airlines
Deal found 5/6£705
Wed 8/706:05
MAN
-
PTY
2 stops19h 26m
United Airlines
Mon 31/815:30
PTY
-
MAN
2 stops33h 00m
United Airlines
Deal found 5/6£706

Find flight deals from Manchester to Panama

Keep the following information in mind while searching for Manchester to Panama flight deals. Data was last updated 9 June 2026.

Round-trip from

£690

One-way from

£526

Popular in

December

Cheapest in

September

Average price

£813
United Airlines
  • United Airlines
  • 1/11-12/12
  • 4 total stops
  • 60h 15m total
  • Manchester to Panama
Search Deals
2/7
  • 2/7
  • 3 total stops
  • 47h 20m total
  • Manchester to Panama
Search Deals
Highest demand for flights based on searches. 3% potential increase in price (£21 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease (£8 potential savings vs. average return price).
Search Deals
Average for round-trip flights in June 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Manchester to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 9 June 2026.
Use the filters below to find and compare flights from Manchester to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Sun 1/11

09:30-14:45

2 stops34h 15m

Panama City Tocumen Intl

Sat 12/12

10:00-17:00

2 stops26h 00m

£690

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Wed 2/12

09:30-17:07

2 stops36h 37m

Panama City Tocumen Intl

Wed 9/12

08:55-17:00

2 stops27h 05m

£695
Fastest return journey

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Sat 24/10

06:05-19:31

2 stops19h 26m

Panama City Tocumen Intl

Tue 24/11

10:00-17:00

2 stops26h 00m

£700

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Sat 8/8

06:05-04:04

2 stops27h 59m

Panama City Tocumen Intl

Wed 26/8

09:45-10:25

2 stops18h 40m

£701

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Tue 27/10

10:30-19:02

2 stops37h 32m

Panama City Tocumen Intl

Tue 24/11

10:00-17:00

2 stops26h 00m

£701

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Mon 26/10

10:30-19:02

2 stops37h 32m

Panama City Tocumen Intl

Mon 23/11

16:41-17:00

2 stops43h 19m

£701

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Sat 8/8

06:05-04:04

2 stops27h 59m

Panama City Tocumen Intl

Sun 30/8

22:55-06:30

2 stops49h 35m

£702

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Tue 21/7

06:05-04:04

2 stops27h 59m

Panama City Tocumen Intl

Tue 28/7

22:55-09:50

2 stops28h 55m

£702

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Thu 2/7

06:05-04:04

2 stops27h 59m

Panama City Tocumen Intl

Thu 16/7

22:55-09:50

2 stops28h 55m

£704

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Wed 8/7

06:05-19:31

2 stops19h 26m

Panama City Tocumen Intl

Mon 31/8

15:30-06:30

3 stops33h 00m

£706

Flights are sorted by cheapest return flights first.

Deals found on 7/6

Showing 1-10 of 21 resultsSorted by cheapest first
1
2
3

Best time to book a flight from Manchester to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Manchester with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to Panama

What is the cheapest month to book a flight from Manchester to Panama?

Currently, February is the cheapest month in which you can book a flight from Manchester to Panama (average of £558). Flying from Manchester to Panama in June is currently the most expensive (average of £744). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated 9 June 2026.
Get a feel of what it's like to fly with KLM,Air France, andTurkish Airlines from Manchester to Panama by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7.8
Good
1,527 reviews
Check prices

Overall

7.8

Boarding

7.8

Crew

8.4

Food

7.3

Entertainment

7.2

Comfort

7.7

Reviews

1 / 20
6.0
Good

Anonymous,Apr 2026

OKC - ATL

Flight was ok - difficult as I had seat next to bathroom.. Food awful
KLM
7.8
Good
1,527 reviews
KLM
7.8
Good
1,527 reviews
Check prices

Overall

7.8

Boarding

7.8

Crew

8.4

Food

7.3

Entertainment

7.2

Comfort

7.7

Reviews

1 / 20
6.0
Good

Anonymous,Apr 2026

OKC - ATL

Flight was ok - difficult as I had seat next to bathroom.. Food awful
Air France
7.4
Good
1,598 reviews
KLM
7.8
Good
1,527 reviews
Check prices

Overall

7.8

Boarding

7.8

Crew

8.4

Food

7.3

Entertainment

7.2

Comfort

7.7

Reviews

1 / 20
6.0
Good

Anonymous,Apr 2026

OKC - ATL

Flight was ok - difficult as I had seat next to bathroom.. Food awful
Turkish Airlines
7.4
Good
4,409 reviews
KLM
7.8
Good
1,527 reviews
Check prices

Overall

7.8

Boarding

7.8

Crew

8.4

Food

7.3

Entertainment

7.2

Comfort

7.7

Reviews

1 / 20
6.0
Good

Anonymous,Apr 2026

OKC - ATL

Flight was ok - difficult as I had seat next to bathroom.. Food awful
United Airlines
7.4
Good
9,801 reviews
KLM
7.8
Good
1,527 reviews
Check prices

Overall

7.8

Boarding

7.8

Crew

8.4

Food

7.3

Entertainment

7.2

Comfort

7.7

Reviews

1 / 20
6.0
Good

Anonymous,Apr 2026

OKC - ATL

Flight was ok - difficult as I had seat next to bathroom.. Food awful
Lufthansa
6.8
Okay
8,050 reviews
KLM
7.8
Good
1,527 reviews
Check prices

Overall

7.8

Boarding

7.8

Crew

8.4

Food

7.3

Entertainment

7.2

Comfort

7.7

Reviews

1 / 20
6.0
Good

Anonymous,Apr 2026

OKC - ATL

Flight was ok - difficult as I had seat next to bathroom.. Food awful

Related info for your journey

Find useful and relevant information for your journey from Manchester to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Manchester to Panama?

    Manchester (MAN) is the airport you will fly out of if you book a flight from Manchester to Panama. It is only a 8.9 mi journey to Manchester (MAN) from Manchester’s city center.

  • How long is the flight from Manchester to Panama?

    United Airlines can get you from Manchester to Panama in just under 34h 15m. Your travel time can differ by up to . Airlines will cover a distance of 5182 mi.

  • Can I find deals for flights from Manchester to Panama that include hotel bookings?

    Yes. In addition to deals on Manchester to Panama flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Manchester to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to Panama.

  • Can I find deals for business class flights from Manchester to Panama?

    Yes. Cheapflights offers flight deals from Manchester to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester to Panama?

    Currently, February is the cheapest month in which you can book a flight from Manchester to Panama (average of £558). Flying from Manchester to Panama in June is currently the most expensive (average of £744). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Manchester to Panama

See prices for flight routes from nearby airports that may be better suited for you.
Heathrow to San José flights
Gatwick to San José flights
Heathrow to Panama City flights
London City to San José flights
Stansted to Panama City flights
Gatwick to Panama City flights
Stansted to San José flights
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Luton to San José flights
Heathrow to Guatemala City flights
Heathrow to Philip S.W.Goldson flights
Gatwick to Guatemala City flights
Heathrow to San Salvador flights
Manchester to Panama City flights
Stansted to Guatemala City flights
Manchester to San José flights
Luton to Panama City flights
London City to Guatemala City flights
Gatwick to San Salvador flights
Heathrow to Liberia flights
Stansted to San Salvador flights
Heathrow to Managua flights
Gatwick to Managua flights
Gatwick to Liberia flights
London City to San Salvador flights
London City to Managua flights
Stansted to Managua flights
Gatwick to Philip S.W.Goldson flights
Edinburgh to Managua flights
Edinburgh to Panama City flights
London City to Liberia flights
Edinburgh to San José flights
Manchester to San Salvador flights
Birmingham to Panama City flights
Manchester to Philip S.W.Goldson flights
Newcastle upon Tyne to San José flights
Manchester to Managua flights
Manchester to Guatemala City flights
Birmingham to San José flights
Edinburgh to Guatemala City flights
Heathrow to Coxen Hole flights
Southampton to San Salvador flights
London City to San Pedro Sula flights
Manchester to Liberia flights
Gatwick to San Pedro Sula flights
Birmingham to San Salvador flights
Birmingham to Philip S.W.Goldson flights
Leeds to San José flights
Leeds to Panama City flights

Top 5 airlines flying from Manchester to Panama

Discover the top 5 airlines that operate flights from Manchester to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 9 June 2026.
AirlineCheapestAverageFlexibilityOn-time
Air FranceCheapest£565Average£716FlexibilityNo cancel feeOn-time77%
Search Air France flights
Turkish AirlinesCheapest£581Average£723FlexibilityNo cancel feeOn-time77%
Search Turkish Airlines flights
KLMCheapest£604Average£851FlexibilityNo cancel feeOn-time75%
Search KLM flights
United AirlinesCheapest£608Average£699FlexibilityNo cancel feeOn-time69%
Search United Airlines flights
LufthansaCheapest£610Average£684FlexibilityNo cancel feeOn-time76%
Search Lufthansa flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Manchester to Panama?

900+ travel sites are searched through when a user searches for a flight using Cheapflights. From the search interface, users can use filters to choose airlines, airports, flight times, cabin classes and more to their preference. Book your flight to Panama from Manchester today with Cheapflights!

Why should you use Cheapflights to find cheap flight tickets from Manchester to Panama?

Cheapflights helps you find that perfect flight to Panama from Manchester by searching from hundreds of airlines and agencies you know and love. We are also free to use, in case you were wondering!

Can Cheapflights find flights from Manchester to Panama with no change fees?

Cheapflights does show flights with no change fees to all users. To see these options for flights from Manchester to Panama, users can toggle the no change fees filter when performing a flight search.

Can Cheapflights notify me if prices for flights from Manchester to Panama become cheaper?

Yes, Cheapflights offers price alerts on Manchester to Panama flights so you can book your travel at the perfect time. Price Alerts can be enabled by clicking the bell icon next to the flight deals above and providing your email address where you want to receive the alerts.

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