Find a great deal and save up to 33% by booking at least 35 days prior to your desired departure date, rather than waiting until the week of travel. According to our data, there are a number of flights available from Southampton to Mytilene within the next two weeks, with the cheapest ticket starting at £309.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Southampton to Mytilene as you normally would.
Information is based on travel restrictions from Southampton Eastleigh to Lesbos
Most visitors from Southampton Eastleigh can enter Lesbos without restrictions.
COVID-19 testing requirements
Visitors from Southampton Eastleigh are not required to present a negative COVID-19 PCR test or antigen result upon entering Lesbos.
Quarantine requirements
Visitors from Southampton Eastleigh are not required to quarantine after entering Lesbos.
Returning to Southampton Eastleigh from Lesbos
COVID-19 testing requirements
Visitors from Lesbos are not required to present a negative COVID-19 PCR test or antigen result upon entering Southampton Eastleigh.
Quarantine requirements
Visitors from Lesbos are not required to quarantine after entering Southampton Eastleigh.