£126+ Cheap flights from Des Moines

This is the cheapest return flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 25/1. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
DSM — LHR
17 Jan — 24 Jan1
1 adult
1 adult, Economy, 0 bags

What to know about flights from Des Moines

Discover essential information about flights departing from Des Moines, including flight schedules, destinations, airlines operating at the Des Moines airport, and any specific guidelines or requirements for travellers. Please note that the information is based on the most recent updates available. Data last updated 18 December 2025.

Good round-trip deal

£978 or less
Price to beat on a round-trip flight from Des Moines.
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Cheapest flights from Des Moines
Explore the most affordable flight options available from Des Moines. Find the lowest fares based on data from user searches, with prices last updated on 18 December 2025.

Thu 29/111:42DSM - INV
2 stops16h 18mAmerican Airlines
Thu 5/211:45INV - DSM
2 stops29h 05mAmerican Airlines
Deal found 14/12£377
Thu 29/110:21DSM - INV
2 stops20h 24mKLM
Thu 5/213:15INV - DSM
2 stops38h 09mKLM
Deal found 15/12£386
Wed 21/117:16DSM - LHR
1 stop12h 24mVirgin Atlantic
Wed 28/108:40LHR - DSM
2 stops18h 14mVirgin Atlantic
Deal found 16/12£401
Fri 30/110:59DSM - EDI
2 stops17h 41mVirgin Atlantic
Fri 6/211:00EDI - DSM
2 stops15h 54mVirgin Atlantic
Deal found 16/12£404
Thu 29/110:59DSM - LHR
1 stop14h 06mVirgin Atlantic
Thu 5/208:40LHR - DSM
2 stops18h 44mVirgin Atlantic
Deal found 15/12£406
Mon 19/111:30DSM - LHR
1 stop12h 25mLufthansa
Mon 26/111:10LHR - DSM
2 stops16h 40mLufthansa
Deal found 17/12£427
Wed 21/111:30DSM - LHR
1 stop12h 25mLufthansa
Wed 28/108:30LHR - DSM
2 stops19h 20mLufthansa
Deal found 15/12£437
Thu 29/117:16DSM - MAN
1 stop11h 14mVirgin Atlantic
Thu 5/213:30MAN - DSM
1 stop14h 59mVirgin Atlantic
Deal found 15/12£437
Thu 29/118:48DSM - MAN
2 stops22h 32mLufthansa
Thu 5/217:40MAN - DSM
2 stops34h 10mLufthansa
Deal found 14/12£439
Thu 29/110:21DSM - EDI
2 stops29h 14mVirgin Atlantic
Thu 5/217:00EDI - DSM
2 stops33h 54mVirgin Atlantic
Deal found 15/12£440
Thu 29/110:59DSM - EDI
2 stops17h 11mKLM
Thu 5/211:00EDI - DSM
2 stops15h 54mKLM
Deal found 15/12£445
Wed 25/218:55DSM - LHR
1 stop10h 20mLufthansa
Mon 2/311:10LHR - DSM
2 stops16h 31mLufthansa
Deal found 16/12£446

Find flights from Des Moines within your budget

 
Find flights departing from Des Moines that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 18 December 2025. In the last 7 days, Cheapflights users made a total of 858,174 searches

Fly to

Heathrow

Route

Depart

Return

Price

Des MoinesInverness

DSM - INV

DSMINV

Des Moines

Fri 30/1

17:51-19:30

2 stops19h 39m

Inverness

Fri 6/2

11:25-23:23

2 stops17h 58m

£377

Des MoinesInverness

DSM - INV

DSMINV

Des Moines

Thu 29/1

11:42-10:00

2 stops16h 18m

Inverness

Thu 5/2

11:45-10:50

2 stops29h 05m

£377

Des MoinesInverness

DSM - INV

DSMINV

Des Moines

Thu 29/1

10:21-12:45

2 stops20h 24m

Inverness

Thu 5/2

13:15-21:24

2 stops38h 09m

£386

Des MoinesEdinburgh

DSM - EDI

DSMEDI

Des Moines

Fri 30/1

10:59-10:40

2 stops17h 41m

Edinburgh Turnhouse

Fri 6/2

11:00-20:54

2 stops15h 54m

£404

Des MoinesManchester

DSM - MAN

DSMMAN

Des Moines

Thu 29/1

18:48-23:20

2 stops22h 32m

Manchester

Thu 5/2

17:40-21:50

2 stops34h 10m

£439

Des MoinesEdinburgh

DSM - EDI

DSMEDI

Des Moines

Thu 29/1

11:30-07:55

2 stops14h 25m

Edinburgh Turnhouse

Thu 5/2

09:25-22:30

2 stops19h 05m

£440

Des MoinesManchester

DSM - MAN

DSMMAN

Des Moines

Thu 29/1

10:21-16:05

2 stops23h 44m

Manchester

Thu 5/2

13:30-21:24

2 stops37h 54m

£445

Des MoinesBirmingham

DSM - BHX

DSMBHX

Des Moines

Thu 29/1

10:59-08:30

2 stops15h 31m

Birmingham

Thu 5/2

06:15-20:54

2 stops20h 39m

£449

Des MoinesGlasgow

DSM - GLA

DSMGLA

Des Moines

Thu 29/1

10:21-09:55

2 stops41h 34m

Glasgow Intl

Thu 5/2

17:20-20:54

2 stops33h 34m

£450

Des MoinesManchester

DSM - MAN

DSMMAN

Des Moines

Fri 30/1

10:59-10:30

2 stops17h 31m

Manchester

Fri 6/2

13:25-22:29

1 stop15h 04m

£451

Flights are sorted by cheapest return flights first.

Deals found on 16/12

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Best time to book a flight from Des Moines

Have a flexible travel schedule? Discover the best time to fly from Des Moines with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Des Moines

Get recent, data-driven insights about flights from Des Moines including ideal travel times, pricing trends, and more.

When is the best time to book a flight from Des Moines?

Use this chart to determine the optimal time to book a return flight from Des Moines to Heathrow. Price data was last updated on 12 December 2025.

Booking 79 days in advance of your planned departure date is, on average, the best time to get cheap flights from Des Moines. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Des Moines?

Currently, November is the cheapest month in which you can book a flight from Des Moines (average of £464). Flying from Des Moines in July will prove the most costly (average of £793). There are multiple factors that influence the price of a flight so comparing airlines, departure airports and times can help keep costs down.

What are popular destinations to fly to from Des Moines?

If you’re flying from Des Moines, these routes are more frequently taken by airlines Chicago (168 flights per day), Detroit (100 flights per day) and Atlanta (99 flights per day).

Minneapolis St Paul
Minneapolis St Paul
From £462

What is the cheapest place to fly to from Des Moines?

The cheapest city to fly to from Des Moines is Minneapolis St Paul, with prices starting at £462. Explore other affordable destinations below.

Minneapolis St Paul
Minneapolis St Paul
From £462

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Related info for your journey

Access useful and relevant information related to your journey from Des Moines. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 18 December 2025.

  • What are the most popular destinations to fly to from Des Moines?

    This month, the top selected destinations from Des Moines are Denver, Hyderabad, Dallas/Fort Worth Airport. Throughout the year, Denver, Cancún, Nashville are some of the top choices made by users flying from Des Moines.

  • What is the cheapest flight from Des Moines to anywhere?

    Users have flown out of Des Moines for as low as £462 to Minneapolis (prices may vary depending on the airline and departure time). On average, users have booked flights for £1,008 to fly from Des Moines.

  • What is the cheapest first class flight from Des Moines?

    If you’re looking for a cheap first-class flight from Des Moines, consider Charlotte. Prices start at £608 so you can fly first-class even on a budget.

  • What is the cheapest month to fly from Des Moines?

    At the present moment the cheapest month to fly from Des Moines is currently November; with July being the most expensive. Prices will vary depending on multiple factors such as booking in advance, airline and departure airports and times.

  • How does Cheapflights help users find flights from Des Moines?

    Cheapflights makes it easy to find flights from Des Moines by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

  • Why should you use Cheapflights to find cheap flight tickets from Des Moines?

    It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Des Moines.

  • Can Cheapflights find flights from Des Moines with no change fees?

    Certainly. Search results for flights from Des Moines shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

  • Can Cheapflights notify me if prices for flights from Des Moines become cheaper?

    Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and use a valid email address to enable the Price Alerts feature. That’s it!

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Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Des Moines?

Cheapflights makes it easy to find flights from Des Moines by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

Why should you use Cheapflights to find cheap flight tickets from Des Moines?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Des Moines.

Can Cheapflights find flights from Des Moines with no change fees?

Certainly. Search results for flights from Des Moines shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Des Moines become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and use a valid email address to enable the Price Alerts feature. That’s it!

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