£164+ Cheap flights from Des Moines

This is the cheapest return flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/5. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
DSM — LHR
10 May — 17 May1
1 adult
1 adult, Economy, 0 bags

Find flights from Des Moines within your budget

 
Find flights departing from Des Moines that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 10 April 2026. In the last 7 days, Cheapflights users made a total of 858,174 searches

Fly to

Route

Depart

Return

Price

Cheapest return flight

Des MoinesEdinburgh

DSM - EDI

DSMEDI

Des Moines

Tue 29/9

18:45-16:25

2 stops15h 40m

Edinburgh Turnhouse

Wed 7/10

06:10-23:01

2 stops22h 51m

£629

Des MoinesEdinburgh

DSM - EDI

DSMEDI

Des Moines

Tue 29/9

15:15-08:25

1 stop11h 10m

Edinburgh Turnhouse

Wed 7/10

11:30-21:17

1 stop15h 47m

£648

Des MoinesEdinburgh

DSM - EDI

DSMEDI

Des Moines

Tue 1/9

10:15-07:05

2 stops14h 50m

Edinburgh Turnhouse

Tue 8/9

09:00-22:26

1 stop19h 26m

£650

Des MoinesEdinburgh

DSM - EDI

DSMEDI

Des Moines

Tue 29/9

09:39-12:00

2 stops20h 21m

Edinburgh Turnhouse

Wed 7/10

19:30-18:56

2 stops29h 26m

£650

Des MoinesLondon

DSM - LHR

DSMLHR

Des Moines

Wed 23/9

11:34-12:35

1 stop19h 01m

London Heathrow

Fri 2/10

14:05-14:11

2 stops30h 06m

£657

Des MoinesLondon

DSM - LHR

DSMLHR

Des Moines

Sun 27/9

09:38-06:50

1 stop15h 12m

London Heathrow

Fri 2/10

09:45-23:28

1 stop19h 43m

£672

Des MoinesLondon

DSM - LHR

DSMLHR

Des Moines

Wed 5/8

06:00-05:55

2 stops17h 55m

London Heathrow

Wed 19/8

11:05-17:02

1 stop11h 57m

£672

Des MoinesGlasgow

DSM - GLA

DSMGLA

Des Moines

Wed 6/5

16:23-08:25

2 stops34h 02m

Glasgow Intl

Wed 20/5

06:00-21:12

2 stops21h 12m

£677

Des MoinesEdinburgh

DSM - EDI

DSMEDI

Des Moines

Thu 1/10

13:05-10:35

2 stops15h 30m

Edinburgh Turnhouse

Wed 7/10

09:00-19:25

2 stops16h 25m

£694

Des MoinesLondon

DSM - LHR

DSMLHR

Des Moines

Tue 5/5

15:20-10:00

2 stops12h 40m

London Heathrow

Tue 12/5

06:50-18:05

2 stops17h 15m

£698

Flights are sorted by cheapest return flights first.

Deals found on 8/4

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from Des Moines

Have a flexible travel schedule? Discover the best time to fly from Des Moines with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Des Moines

Get recent, data-driven insights about flights from Des Moines including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Des Moines?

Currently, November is the cheapest month in which you can book a flight from Des Moines (average of £467). Flying from Des Moines in July will prove the most costly (average of £783). There are multiple factors that influence the price of a flight so comparing airlines, departure airports and times can help keep costs down.

What are popular destinations to fly to from Des Moines?

If you’re flying from Des Moines, these routes are more frequently taken by airlines Chicago (510 flights per day), Detroit (164 flights per day) and Atlanta (122 flights per day).

Minneapolis St Paul
Minneapolis St Paul
From £382
Chicago
Chicago
From £212

What is the cheapest place to fly to from Des Moines?

The cheapest city to fly to from Des Moines is Chicago, with prices starting at £212. Explore other affordable destinations below.

Chicago
Chicago
From £212
Minneapolis St Paul
Minneapolis St Paul
From £382

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Direct flights from Iowa

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Related info for your journey

Access useful and relevant information related to your journey from Des Moines. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 10 April 2026.

  • What are the most popular destinations to fly to from Des Moines?

    This month, the top selected destinations from Des Moines are Las Vegas, Denver, Cancún. Throughout the year, Las Vegas, Denver, Los Angeles are some of the top choices made by users flying from Des Moines.

  • What is the cheapest flight from Des Moines to anywhere?

    Users have flown out of Des Moines for as low as £212 to Chicago O'Hare Intl Airport (prices may vary depending on the airline and departure time). On average, users have booked flights for £743 to fly from Des Moines.

  • What is the cheapest first class flight from Des Moines?

    If you’re looking for a cheap first-class flight from Des Moines, consider Charlotte. Prices start at £606 so you can fly first-class even on a budget.

  • What is the cheapest month to fly from Des Moines?

    At the present moment the cheapest month to fly from Des Moines is currently November; with July being the most expensive. Prices will vary depending on multiple factors such as booking in advance, airline and departure airports and times.

  • How does Cheapflights help users find flights from Des Moines?

    Cheapflights makes it easy to find flights from Des Moines by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

  • Why should you use Cheapflights to find cheap flight tickets from Des Moines?

    It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Des Moines.

  • Can Cheapflights find flights from Des Moines with no change fees?

    Certainly. Search results for flights from Des Moines shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

  • Can Cheapflights notify me if prices for flights from Des Moines become cheaper?

    Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and use a valid email address to enable the Price Alerts feature. That’s it!

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Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Des Moines?

Cheapflights makes it easy to find flights from Des Moines by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

Why should you use Cheapflights to find cheap flight tickets from Des Moines?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Des Moines.

Can Cheapflights find flights from Des Moines with no change fees?

Certainly. Search results for flights from Des Moines shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Des Moines become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and use a valid email address to enable the Price Alerts feature. That’s it!

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