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£111+ Cheap flights from Des Moines

This is the cheapest return flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 18/1. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
DSM — LHR
25 Dec — 1 Jan1
1 adult
1 adult, Economy, 0 bags

What to know about flights from Des Moines

Discover essential information about flights departing from Des Moines, including flight schedules, destinations, airlines operating at the Des Moines airport, and any specific guidelines or requirements for travellers. Please note that the information is based on the most recent updates available. Data last updated 25 November 2025.

Cheapest airline

Virgin Atlantic
On average, Virgin Atlantic currently has the cheapest one-way flight from Des Moines (avg. price of £1,113).
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Enter your travel dates to find the best prices.

Cheapest flights from Des Moines
Explore the most affordable flight options available from Des Moines. Find the lowest fares based on data from user searches, with prices last updated on 25 November 2025.

Thu 8/117:51DSM - INV
2 stops19h 49mAmerican Airlines
Thu 15/111:45INV - DSM
2 stops17h 38mAmerican Airlines
Deal found 24/11£382
Fri 20/210:57DSM - INV
2 stops22h 43mVirgin Atlantic
Tue 24/213:15INV - DSM
2 stops39h 13mVirgin Atlantic
Deal found 22/11£399
Thu 8/110:59DSM - LHR
1 stop14h 06mVirgin Atlantic
Thu 15/110:00LHR - DSM
2 stops16h 54mVirgin Atlantic
Deal found 24/11£417
Thu 8/108:00DSM - LHR
2 stops17h 10mAir Canada
Thu 15/113:25LHR - DSM
2 stops31h 08mAir Canada
Deal found 24/11£431
Fri 9/110:59DSM - LHR
1 stop14h 06mVirgin Atlantic
Fri 16/111:45LHR - DSM
2 stops15h 09mVirgin Atlantic
Deal found 24/11£439
Tue 6/118:48DSM - LHR
2 stops30h 22mMultiple Airlines
Tue 13/107:40LHR - DSM
2 stops20h 10mMultiple Airlines
Deal found 24/11£440
Thu 8/118:48DSM - LHR
1 stop10h 27mLufthansa
Thu 15/107:40LHR - DSM
1 stop20h 10mLufthansa
Deal found 24/11£443
Tue 6/106:54DSM - LHR
1 stop18h 11mVirgin Atlantic
Tue 13/110:00LHR - DSM
2 stops16h 54mVirgin Atlantic
Deal found 24/11£443
Thu 8/110:59DSM - LHR
1 stop14h 06mVirgin Atlantic
Wed 21/111:05LHR - DSM
1 stop16h 19mVirgin Atlantic
Deal found 24/11£448
Tue 6/118:48DSM - LHR
2 stops30h 22mAir Canada
Tue 13/113:25LHR - DSM
2 stops27h 30mAir Canada
Deal found 24/11£449
Thu 8/118:48DSM - BHX
2 stops16h 12mLufthansa
Thu 15/110:45BHX - DSM
2 stops17h 05mLufthansa
Deal found 24/11£450
Wed 7/118:48DSM - LHR
1 stop10h 27mLufthansa
Wed 14/110:25LHR - DSM
1 stop17h 25mLufthansa
Deal found 23/11£452

Find flights from Des Moines within your budget

 
Find flights departing from Des Moines that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 25 November 2025. In the last 7 days, Cheapflights users made a total of 858,174 searches

Fly to

Heathrow

Route

Depart

Return

Price

Des MoinesInverness

DSM - INV

DSMINV

Des Moines

Thu 8/1

17:51-19:40

2 stops19h 49m

Inverness

Thu 15/1

11:45-23:23

2 stops17h 38m

£382

Des MoinesInverness

DSM - INV

DSMINV

Des Moines

Fri 20/2

10:57-15:40

2 stops22h 43m

Inverness

Tue 24/2

13:15-22:28

2 stops39h 13m

£399

Des MoinesInverness

DSM - INV

DSMINV

Des Moines

Fri 20/2

10:37-15:40

2 stops23h 03m

Inverness

Tue 24/2

13:15-20:49

2 stops37h 34m

£399

Des MoinesLondon

DSM - LHR

DSMLHR

Des Moines

Fri 9/1

11:30-05:55

1 stop12h 25m

London Heathrow

Fri 16/1

13:35-21:50

1 stop14h 15m

£460

Des MoinesGlasgow

DSM - GLA

DSMGLA

Des Moines

Thu 8/1

17:51-16:40

2 stops16h 49m

Glasgow Intl

Thu 15/1

08:40-21:04

2 stops18h 24m

£461

Des MoinesBirmingham

DSM - BHX

DSMBHX

Des Moines

Wed 7/1

17:16-08:30

2 stops33h 14m

Birmingham

Wed 14/1

06:15-21:24

2 stops21h 09m

£463

Des MoinesLondon

DSM - LHR

DSMLHR

Des Moines

Wed 7/1

05:35-06:25

1 stop18h 50m

London Heathrow

Wed 14/1

09:40-20:54

2 stops17h 14m

£463

Des MoinesBirmingham

DSM - BHX

DSMBHX

Des Moines

Thu 8/1

18:48-17:00

2 stops16h 12m

Birmingham

Thu 15/1

10:45-21:50

2 stops17h 05m

£464

Des MoinesEdinburgh

DSM - EDI

DSMEDI

Des Moines

Thu 8/1

18:48-17:05

2 stops16h 17m

Edinburgh Turnhouse

Thu 15/1

12:45-21:50

2 stops39h 05m

£464

Des MoinesLondon

DSM - LHR

DSMLHR

Des Moines

Fri 20/2

18:49-11:15

1 stop10h 26m

London Heathrow

Fri 27/2

11:10-21:51

2 stops16h 41m

£466

Flights are sorted by cheapest return flights first.

Deals found on 23/11

Showing 1-10 of 60 results
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Best time to book a flight from Des Moines

Have a flexible travel schedule? Discover the best time to fly from Des Moines with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Des Moines

Get recent, data-driven insights about flights from Des Moines including ideal travel times, pricing trends, and more.

When is the best time to book a flight from Des Moines?

Use this chart to determine the optimal time to book a return flight from Des Moines to Heathrow. Price data was last updated on 21 November 2025.

Booking 79 days in advance of your planned departure date is, on average, the best time to get cheap flights from Des Moines. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Des Moines?

Currently, November is the cheapest month in which you can book a flight from Des Moines (average of £476). Flying from Des Moines in July will prove the most costly (average of £810). There are multiple factors that influence the price of a flight so comparing airlines, departure airports and times can help keep costs down.

Which airlines fly from Des Moines?

Many airlines operate round-trip flights from Des Moines: Virgin Atlantic, United Airlines. These airlines fly to the following popular destinations: London.

Virgin Atlantic
Virgin Atlantic
From £506
United Airlines
United Airlines
From £493

Airline reviews for flights from Des Moines

Get insights into the airlines that provide service from Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing airline for your flight from Des Moines. In the last 7 days, Cheapflights users made a total of 858,174 searches.
Read through reviews of airlines serving Des Moines, such as Virgin Atlantic and United Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Virgin Atlantic
7.5
Good
675 reviews
Check prices

Entertainment

7.5

Overall

7.5

Comfort

7.3

Food

6.9

Boarding

7.7

Crew

8.2

Reviews

1 / 20
6.0
Good

Pratap,Aug 2025

JFK - LHR

The flight is clean, food good and the staff are excellent! Very professional, polite and accommodating. The seat itself is really mediocre. Can’t believe there is not inch of storage space. Believe it or not it there is not place even to put away your phone or pen!! Very very surprising and terribly inconvenient. No coat hanger hook either. Had to give it away. ALL IN ALL VERY INCONVENIENT business class seat compared to their peers. What is even more surprising is that this on their relatively new fleet of Airbus A350-1000. I was having com platelets different expectations of Virgin and this has disappointed me. Everything else is just as good and as you would expect from Virgin!
Virgin Atlantic
7.5
Good
675 reviews
Virgin Atlantic
7.5
Good
675 reviews
Check prices

Entertainment

7.5

Overall

7.5

Comfort

7.3

Food

6.9

Boarding

7.7

Crew

8.2

Reviews

1 / 20
6.0
Good

Pratap,Aug 2025

JFK - LHR

The flight is clean, food good and the staff are excellent! Very professional, polite and accommodating. The seat itself is really mediocre. Can’t believe there is not inch of storage space. Believe it or not it there is not place even to put away your phone or pen!! Very very surprising and terribly inconvenient. No coat hanger hook either. Had to give it away. ALL IN ALL VERY INCONVENIENT business class seat compared to their peers. What is even more surprising is that this on their relatively new fleet of Airbus A350-1000. I was having com platelets different expectations of Virgin and this has disappointed me. Everything else is just as good and as you would expect from Virgin!
United Airlines
7.4
Good
9,044 reviews
Virgin Atlantic
7.5
Good
675 reviews
Check prices

Entertainment

7.5

Overall

7.5

Comfort

7.3

Food

6.9

Boarding

7.7

Crew

8.2

Reviews

1 / 20
6.0
Good

Pratap,Aug 2025

JFK - LHR

The flight is clean, food good and the staff are excellent! Very professional, polite and accommodating. The seat itself is really mediocre. Can’t believe there is not inch of storage space. Believe it or not it there is not place even to put away your phone or pen!! Very very surprising and terribly inconvenient. No coat hanger hook either. Had to give it away. ALL IN ALL VERY INCONVENIENT business class seat compared to their peers. What is even more surprising is that this on their relatively new fleet of Airbus A350-1000. I was having com platelets different expectations of Virgin and this has disappointed me. Everything else is just as good and as you would expect from Virgin!

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Related info for your journey

Access useful and relevant information related to your journey from Des Moines. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 25 November 2025.

  • What are the most popular destinations to fly to from Des Moines?

    This month, the top selected destinations from Des Moines are Denver, Cancún, Dallas/Fort Worth Airport. Throughout the year, Denver, Cancún, Nashville are some of the top choices made by users flying from Des Moines.

  • What is the cheapest first class flight from Des Moines?

    If you’re looking for a cheap first-class flight from Des Moines, consider Charlotte. Prices start at £620 so you can fly first-class even on a budget.

  • What is the cheapest month to fly from Des Moines?

    At the present moment the cheapest month to fly from Des Moines is currently November; with July being the most expensive. Prices will vary depending on multiple factors such as booking in advance, airline and departure airports and times.

  • Where are the cheapest places to fly to from Des Moines?

    Check out the cheapest flights from Des Moines to embark to:
    Travel from Des Moines to London from £439 round trip

  • How does Cheapflights help users find flights from Des Moines?

    Cheapflights makes it easy to find flights from Des Moines by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

  • Why should you use Cheapflights to find cheap flight tickets from Des Moines?

    It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Des Moines.

  • Can Cheapflights find flights from Des Moines with no change fees?

    Certainly. Search results for flights from Des Moines shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

  • Can Cheapflights notify me if prices for flights from Des Moines become cheaper?

    Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and use a valid email address to enable the Price Alerts feature. That’s it!

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How does Cheapflights help users find flights from Des Moines?

Cheapflights makes it easy to find flights from Des Moines by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

Why should you use Cheapflights to find cheap flight tickets from Des Moines?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Des Moines.

Can Cheapflights find flights from Des Moines with no change fees?

Certainly. Search results for flights from Des Moines shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Des Moines become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and use a valid email address to enable the Price Alerts feature. That’s it!

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