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£95+ Cheap flights from Des Moines

This is the cheapest return flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 22/1. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
DSM — LHR
17 Dec — 24 Dec1
1 adult
1 adult, Economy, 0 bags

What to know about flights from Des Moines

Discover essential information about flights departing from Des Moines, including flight schedules, destinations, airlines operating at the Des Moines airport, and any specific guidelines or requirements for travellers. Please note that the information is based on the most recent updates available. Data last updated 17 November 2025.

Cheapest airline

Virgin Atlantic
On average, Virgin Atlantic currently has the cheapest one-way flight from Des Moines (avg. price of £1,106).
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Enter your travel dates to find the best prices.

Cheapest flights from Des Moines
Explore the most affordable flight options available from Des Moines. Find the lowest fares based on data from user searches, with prices last updated on 17 November 2025.

Fri 20/218:49DSM - LHR
1 stop10h 26mLufthansa
Fri 27/208:45LHR - DSM
2 stops19h 06mLufthansa
Deal found 16/11£464
Thu 5/216:25DSM - GLA
2 stops16h 45mAmerican Airlines
Mon 9/207:35GLA - DSM
2 stops19h 29mAmerican Airlines
Deal found 14/11£467
Mon 1/1211:26DSM - LHR
1 stop12h 29mUnited Airlines
Tue 9/1206:35LHR - DSM
2 stops16h 49mUnited Airlines
Deal found 17/11£468
Fri 16/111:26DSM - MAN
1 stop17h 04mVirgin Atlantic
Tue 20/113:30MAN - DSM
1 stop15h 01mVirgin Atlantic
Deal found 14/11£470
Thu 19/218:49DSM - LHR
2 stops20h 11mLufthansa
Mon 23/211:10LHR - DSM
2 stops16h 41mLufthansa
Deal found 16/11£470
Wed 21/111:26DSM - MAN
1 stop17h 04mDelta
Sun 25/113:00MAN - DSM
1 stop15h 29mDelta
Deal found 16/11£470
Wed 10/1209:00DSM - LHR
2 stops16h 10mAir Canada
Wed 17/1216:20LHR - DSM
2 stops24h 30mAir Canada
Deal found 15/11£473
Mon 1/1214:45DSM - LHR
2 stops14h 55mDelta
Tue 9/1206:30LHR - DSM
2 stops17h 17mDelta
Deal found 17/11£473
Wed 28/108:00DSM - LHR
2 stops17h 10mUnited Airlines
Mon 2/206:50LHR - DSM
2 stops16h 57mUnited Airlines
Deal found 15/11£474
Fri 16/117:16DSM - MAN
1 stop11h 14mDelta
Tue 20/113:30MAN - DSM
1 stop27h 08mDelta
Deal found 15/11£474
Fri 13/214:01DSM - MAN
2 stops20h 34mAmerican Airlines
Sat 21/206:15MAN - DSM
2 stops18h 09mAmerican Airlines
Deal found 15/11£475
Wed 28/117:16DSM - LHR
1 stop12h 24mDelta
Sun 1/208:40LHR - DSM
2 stops18h 14mDelta
Deal found 15/11£476

Find flights from Des Moines within your budget

 
Find flights departing from Des Moines that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 17 November 2025. In the last 7 days, Cheapflights users made a total of 858,174 searches

Fly to

Heathrow

Route

Depart

Return

Price

Des MoinesLondon

DSM - LHR

DSMLHR

Des Moines

Thu 19/2

18:49-11:15

1 stop10h 26m

London Heathrow

Mon 23/2

07:40-21:51

2 stops20h 11m

£464

Des MoinesLondon

DSM - LHR

DSMLHR

Des Moines

Mon 1/12

11:26-05:55

1 stop12h 29m

London Heathrow

Tue 9/12

06:35-17:24

2 stops16h 49m

£468

Des MoinesManchester

DSM - MAN

DSMMAN

Des Moines

Wed 21/1

11:26-10:30

1 stop17h 04m

Manchester

Sun 25/1

13:00-22:31

1 stop15h 31m

£470

Des MoinesManchester

DSM - MAN

DSMMAN

Des Moines

Wed 21/1

17:16-10:30

1 stop11h 14m

Manchester

Sun 25/1

13:00-22:29

1 stop15h 29m

£470

Des MoinesManchester

DSM - MAN

DSMMAN

Des Moines

Fri 16/1

17:16-10:30

1 stop11h 14m

Manchester

Tue 20/1

13:30-22:29

1 stop14h 59m

£470

Des MoinesLondon

DSM - LHR

DSMLHR

Des Moines

Mon 1/12

17:52-13:45

2 stops13h 53m

London Heathrow

Tue 9/12

06:30-17:47

2 stops17h 17m

£473

Des MoinesLondon

DSM - LHR

DSMLHR

Des Moines

Wed 28/1

15:35-07:55

1 stop10h 20m

London Heathrow

Mon 2/2

06:50-21:50

2 stops21h 00m

£474

Des MoinesLondon

DSM - LHR

DSMLHR

Des Moines

Thu 29/1

08:00-05:55

1 stop15h 55m

London Heathrow

Mon 2/2

06:50-17:47

2 stops16h 57m

£474

Des MoinesLondon

DSM - LHR

DSMLHR

Des Moines

Fri 30/1

15:04-10:15

1 stop13h 11m

London Heathrow

Mon 2/2

06:50-17:47

2 stops16h 57m

£474

Des MoinesManchester

DSM - MAN

DSMMAN

Des Moines

Fri 13/2

10:00-14:20

2 stops22h 20m

Manchester

Sat 21/2

09:50-18:24

2 stops14h 34m

£475

Flights are sorted by cheapest return flights first.

Deals found on 15/11

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Best time to book a flight from Des Moines

Have a flexible travel schedule? Discover the best time to fly from Des Moines with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Des Moines

Get recent, data-driven insights about flights from Des Moines including ideal travel times, pricing trends, and more.

When is the best time to book a flight from Des Moines?

Use this chart to determine the optimal time to book a return flight from Des Moines to Heathrow. Price data was last updated on 14 November 2025.

Booking 79 days in advance of your planned departure date is, on average, the best time to get cheap flights from Des Moines. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Des Moines?

Currently, November is the cheapest month in which you can book a flight from Des Moines (average of £473). Flying from Des Moines in July will prove the most costly (average of £805). There are multiple factors that influence the price of a flight so comparing airlines, departure airports and times can help keep costs down.

Which airlines fly from Des Moines?

Many airlines operate round-trip flights from Des Moines: Virgin Atlantic, United Airlines. These airlines fly to the following popular destinations: London.

Virgin Atlantic
Virgin Atlantic
From £503
United Airlines
United Airlines
From £490

Airline reviews for flights from Des Moines

Get insights into the airlines that provide service from Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing airline for your flight from Des Moines. In the last 7 days, Cheapflights users made a total of 858,174 searches.
Read through reviews of airlines serving Des Moines, such as Virgin Atlantic and United Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Virgin Atlantic
7.5
Good
673 reviews
Check prices

Boarding

7.7

Food

6.9

Overall

7.5

Crew

8.1

Entertainment

7.5

Comfort

7.3

Reviews

1 / 20
6.0
Good

Pratap,Aug 2025

JFK - LHR

The flight is clean, food good and the staff are excellent! Very professional, polite and accommodating. The seat itself is really mediocre. Can’t believe there is not inch of storage space. Believe it or not it there is not place even to put away your phone or pen!! Very very surprising and terribly inconvenient. No coat hanger hook either. Had to give it away. ALL IN ALL VERY INCONVENIENT business class seat compared to their peers. What is even more surprising is that this on their relatively new fleet of Airbus A350-1000. I was having com platelets different expectations of Virgin and this has disappointed me. Everything else is just as good and as you would expect from Virgin!
Virgin Atlantic
7.5
Good
673 reviews
Virgin Atlantic
7.5
Good
673 reviews
Check prices

Boarding

7.7

Food

6.9

Overall

7.5

Crew

8.1

Entertainment

7.5

Comfort

7.3

Reviews

1 / 20
6.0
Good

Pratap,Aug 2025

JFK - LHR

The flight is clean, food good and the staff are excellent! Very professional, polite and accommodating. The seat itself is really mediocre. Can’t believe there is not inch of storage space. Believe it or not it there is not place even to put away your phone or pen!! Very very surprising and terribly inconvenient. No coat hanger hook either. Had to give it away. ALL IN ALL VERY INCONVENIENT business class seat compared to their peers. What is even more surprising is that this on their relatively new fleet of Airbus A350-1000. I was having com platelets different expectations of Virgin and this has disappointed me. Everything else is just as good and as you would expect from Virgin!
United Airlines
7.4
Good
9,014 reviews
Virgin Atlantic
7.5
Good
673 reviews
Check prices

Boarding

7.7

Food

6.9

Overall

7.5

Crew

8.1

Entertainment

7.5

Comfort

7.3

Reviews

1 / 20
6.0
Good

Pratap,Aug 2025

JFK - LHR

The flight is clean, food good and the staff are excellent! Very professional, polite and accommodating. The seat itself is really mediocre. Can’t believe there is not inch of storage space. Believe it or not it there is not place even to put away your phone or pen!! Very very surprising and terribly inconvenient. No coat hanger hook either. Had to give it away. ALL IN ALL VERY INCONVENIENT business class seat compared to their peers. What is even more surprising is that this on their relatively new fleet of Airbus A350-1000. I was having com platelets different expectations of Virgin and this has disappointed me. Everything else is just as good and as you would expect from Virgin!

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Related info for your journey

Access useful and relevant information related to your journey from Des Moines. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 17 November 2025.

  • What are the most popular destinations to fly to from Des Moines?

    This month, the top selected destinations from Des Moines are Denver, Cancún, Dallas/Fort Worth Airport. Throughout the year, Denver, Cancún, Nashville are some of the top choices made by users flying from Des Moines.

  • What is the cheapest first class flight from Des Moines?

    If you’re looking for a cheap first-class flight from Des Moines, consider Charlotte. Prices start at £617 so you can fly first-class even on a budget.

  • What is the cheapest month to fly from Des Moines?

    At the present moment the cheapest month to fly from Des Moines is currently November; with July being the most expensive. Prices will vary depending on multiple factors such as booking in advance, airline and departure airports and times.

  • How does Cheapflights help users find flights from Des Moines?

    Cheapflights makes it easy to find flights from Des Moines by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

  • Why should you use Cheapflights to find cheap flight tickets from Des Moines?

    It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Des Moines.

  • Can Cheapflights find flights from Des Moines with no change fees?

    Certainly. Search results for flights from Des Moines shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

  • Can Cheapflights notify me if prices for flights from Des Moines become cheaper?

    Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and use a valid email address to enable the Price Alerts feature. That’s it!

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How does Cheapflights help users find flights from Des Moines?

Cheapflights makes it easy to find flights from Des Moines by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

Why should you use Cheapflights to find cheap flight tickets from Des Moines?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Des Moines.

Can Cheapflights find flights from Des Moines with no change fees?

Certainly. Search results for flights from Des Moines shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Des Moines become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and use a valid email address to enable the Price Alerts feature. That’s it!

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