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£100+ Cheap flights from Des Moines

This is the cheapest return flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 15/10. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
DSM — LHR
18 out — 25 out1
1 adult
1 adult, Economy

What to know about flights from Des Moines

Discover essential information about flights departing from Des Moines, including flight schedules, destinations, airlines operating at the Des Moines airport, and any specific guidelines or requirements for travellers. Please note that the information is based on the most recent updates available. Data last updated 18 setembro 2025.

Good round-trip deal

£129 or less
Price to beat on a round-trip flight from Des Moines.
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Find flights from Des Moines

Cheapest flights from Des Moines
Explore the most affordable flight options available from Des Moines. Find the lowest fares based on data from user searches, with prices last updated on 18 setembro 2025.

ter 7/1010:50DSM - LHR
1 stop14h 25mVirgin Atlantic
qui 16/1011:45LHR - DSM
1 stop14h 50mVirgin Atlantic
Deal found 16/9£432
sex 28/1111:30DSM - INV
2 stops18h 20mAmerican Airlines
qua 10/1210:30INV - DSM
2 stops19h 18mAmerican Airlines
Deal found 16/9£439
qua 1/1018:30DSM - LHR
1 stop13h 00mDelta
qua 8/1011:30LHR - DSM
2 stops17h 00mDelta
Deal found 16/9£456
ter 7/1018:39DSM - LHR
1 stop12h 51mDelta
qui 16/1008:40LHR - DSM
2 stops18h 23mDelta
Deal found 15/9£457
ter 18/1114:19DSM - LHR
1 stop14h 06mIberia
ter 25/1114:10LHR - DSM
1 stop15h 34mIberia
Deal found 18/9£462
qua 15/1014:13DSM - LHR
1 stop11h 02mDelta
qui 23/1012:25LHR - DSM
1 stop14h 38mDelta
Deal found 16/9£462
seg 16/210:15DSM - LHR
1 stop16h 30mDelta
qui 26/206:20LHR - DSM
2 stops20h 33mDelta
Deal found 17/9£463
seg 10/1114:17DSM - LHR
2 stops21h 23mScandinavian Airlines
qui 13/1106:40LHR - DSM
2 stops21h 53mScandinavian Airlines
Deal found 16/9£465
dom 30/1117:26DSM - INV
2 stops19h 34mAmerican Airlines
seg 8/1212:20INV - DSM
2 stops15h 42mAmerican Airlines
Deal found 16/9£468
dom 2/1114:40DSM - INV
2 stops16h 05mDelta
dom 9/1113:15INV - DSM
2 stops34h 31mDelta
Deal found 17/9£471
qua 15/1015:48DSM - GLA
2 stops16h 27mAmerican Airlines
qua 29/1008:40GLA - DSM
2 stops19h 28mAmerican Airlines
Deal found 17/9£482
dom 30/1113:06DSM - INV
2 stops23h 54mBritish Airways
seg 8/1219:45INV - DSM
2 stops32h 17mBritish Airways
Deal found 17/9£484

Find flights from Des Moines within your budget

 
Find flights departing from Des Moines that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 18 setembro 2025. In the last 7 days, Cheapflights users made a total of 858,174 searches

Fly to

Heathrow

Route

Depart

Return

Price

Des MoinesInverness

DSM - INV

DSMINV

Des Moines

sex 28/11

11:30-11:50

2 stops18h 20m

Inverness

qua 10/12

10:30-23:48

2 stops19h 18m

£439

Des MoinesLondon

DSM - LHR

DSMLHR

Des Moines

ter 7/10

17:32-13:10

1 stop13h 38m

London Heathrow

qui 16/10

11:45-20:35

1 stop14h 50m

£456

Des MoinesLondon

DSM - LHR

DSMLHR

Des Moines

ter 7/10

14:40-13:10

1 stop16h 30m

London Heathrow

qui 16/10

06:30-20:35

2 stops20h 05m

£457

Des MoinesLondon

DSM - LHR

DSMLHR

Des Moines

dom 30/11

11:00-07:05

1 stop14h 05m

London Heathrow

ter 9/12

11:30-22:33

2 stops17h 03m

£457

Des MoinesLondon

DSM - LHR

DSMLHR

Des Moines

ter 7/10

18:07-10:30

1 stop10h 23m

London Heathrow

qui 16/10

13:10-20:11

1 stop13h 01m

£459

Des MoinesLondon

DSM - LHR

DSMLHR

Des Moines

qua 1/10

14:05-11:25

2 stops15h 20m

London Heathrow

qua 8/10

11:30-22:30

2 stops17h 00m

£459

Des MoinesLondon

DSM - LHR

DSMLHR

Des Moines

ter 14/10

14:13-07:15

1 stop11h 02m

London Heathrow

ter 21/10

11:20-22:30

1 stop17h 10m

£462

Des MoinesInverness

DSM - INV

DSMINV

Des Moines

dom 30/11

17:26-19:00

2 stops19h 34m

Inverness

seg 8/12

12:20-22:02

2 stops15h 42m

£468

Des MoinesInverness

DSM - INV

DSMINV

Des Moines

dom 30/11

19:00-19:00

2 stops18h 00m

Inverness

seg 8/12

19:45-18:34

2 stops28h 49m

£471

Des MoinesInverness

DSM - INV

DSMINV

Des Moines

dom 2/11

14:40-12:45

2 stops16h 05m

Inverness

dom 9/11

13:15-17:46

2 stops34h 31m

£471

Flights are sorted by cheapest return flights first.

Deals found on 16/9

Showing 1-10 of 60 results
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Best time to book a flight from Des Moines

Have a flexible travel schedule? Discover the best time to fly from Des Moines with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Des Moines

Get recent, data-driven insights about flights from Des Moines including ideal travel times, pricing trends, and more.

When is the best time to book a flight from Des Moines?

Use this chart to determine the optimal time to book a return flight from Des Moines to Heathrow. Price data was last updated on 12 September 2025.

Booking 20 days in advance of your planned departure date is, on average, the best time to get cheap flights from Des Moines. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Des Moines?

Currently, September is the cheapest month in which you can book a flight from Des Moines (average of £474). Flying from Des Moines in July will prove the most costly (average of £796). There are multiple factors that influence the price of a flight so comparing airlines, departure airports and times can help keep costs down.

Which airlines fly from Des Moines?

Many airlines operate round-trip flights from Des Moines: Virgin Atlantic, United Airlines. These airlines fly to the following popular destinations: London.

Virgin Atlantic
Virgin Atlantic
From £638
British Airways
British Airways
From £689
United Airlines
United Airlines
From £645

What are popular destinations to fly to from Des Moines?

If you’re flying from Des Moines, these routes are more frequently taken by airlines Chicago (508 flights per day), Detroit (156 flights per day) and Atlanta (150 flights per day).

Orlando
Orlando
From £176

What is the cheapest place to fly to from Des Moines?

The cheapest city to fly to from Des Moines is Orlando, with prices starting at £129. Explore other affordable destinations below.

Orlando
Orlando
From £176

Airline reviews for flights from Des Moines

Get insights into the airlines that provide service from Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing airline for your flight from Des Moines. In the last 7 days, Cheapflights users made a total of 858,174 searches.
Read through reviews of airlines serving Des Moines, such as United Airlines and Virgin Atlantic. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,926 reviews
Check prices

Comfort

7.3

Entertainment

7.1

Food

6.6

Boarding

7.7

Crew

8.1

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Julia,Sept 2025

BUF - DEN

The staff were amazing, from check in to boarding and on the flight. The range of entertainment options were really good as well.
United Airlines
7.4
Good
8,926 reviews
United Airlines
7.4
Good
8,926 reviews
Check prices

Comfort

7.3

Entertainment

7.1

Food

6.6

Boarding

7.7

Crew

8.1

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Julia,Sept 2025

BUF - DEN

The staff were amazing, from check in to boarding and on the flight. The range of entertainment options were really good as well.
Virgin Atlantic
7.4
Good
664 reviews
United Airlines
7.4
Good
8,926 reviews
Check prices

Comfort

7.3

Entertainment

7.1

Food

6.6

Boarding

7.7

Crew

8.1

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Julia,Sept 2025

BUF - DEN

The staff were amazing, from check in to boarding and on the flight. The range of entertainment options were really good as well.

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Related info for your journey

Access useful and relevant information related to your journey from Des Moines. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 18 setembro 2025.

  • What are the most popular destinations to fly to from Des Moines?

    This month, the top selected destinations from Des Moines are Denver, Boston, Nashville. Throughout the year, Denver, Cancún, Nashville are some of the top choices made by users flying from Des Moines.

  • What is the cheapest flight from Des Moines to anywhere?

    Users have flown out of Des Moines for as low as £129 to Orlando Sanford Intl Airport (prices may vary depending on the airline and departure time). On average, users have booked flights for £131 to fly from Des Moines.

  • What are the cheapest airlines flying from Des Moines to anywhere?

    Over the past few days, we've found that Virgin Atlantic, United Airlines, and British Airways have the cheapest prices from Des Moines. Virgin Atlantic flights from Des Moines to London Heathrow (£468), United Airlines flights from Des Moines to London Heathrow (£473), and British Airways flights from Des Moines to London (£505).

  • What is the cheapest month to fly from Des Moines?

    At the present moment the cheapest month to fly from Des Moines is currently September; with July being the most expensive. Prices will vary depending on multiple factors such as booking in advance, airline and departure airports and times.

  • How does Cheapflights help users find flights from Des Moines?

    Cheapflights makes it easy to find flights from Des Moines by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

  • Why should you use Cheapflights to find cheap flight tickets from Des Moines?

    It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Des Moines.

  • Can Cheapflights find flights from Des Moines with no change fees?

    Certainly. Search results for flights from Des Moines shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

  • Can Cheapflights notify me if prices for flights from Des Moines become cheaper?

    Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and use a valid email address to enable the Price Alerts feature. That’s it!

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Fly with Cheapflights

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How does Cheapflights help users find flights from Des Moines?

Cheapflights makes it easy to find flights from Des Moines by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

Why should you use Cheapflights to find cheap flight tickets from Des Moines?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Des Moines.

Can Cheapflights find flights from Des Moines with no change fees?

Certainly. Search results for flights from Des Moines shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Des Moines become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and use a valid email address to enable the Price Alerts feature. That’s it!

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