£151+ Cheap flights from Panama City, Florida

This is the cheapest return flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/3. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
ECP — LHR
27 Feb — 6 Mar1
1 adult
1 adult, Economy, 0 bags

What to know about flights from Panama City

Discover essential information about flights departing from Panama City, including flight schedules, destinations, airlines operating at the Panama City airport, and any specific guidelines or requirements for travellers. Please note that the information is based on the most recent updates available. Data last updated 28 January 2026.

Cheapest one-way flight

£589

Most popular destination

Atlanta Hartsfield-Jackson (ATL)

Good one-way deal

£597 or less
The cheapest one-way flight from Panama City NW Florida Beaches is currently to Atlanta Hartsfield-Jackson.
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Atlanta Hartsfield-Jackson (ATL) is currently the most popular flight destination from Panama City NW Florida Beaches (average return price of £654).
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Price to beat on a one-way flight from Panama City NW Florida Beaches.
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Find flights from Panama City

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Cheapest flights from Panama City
Explore the most affordable flight options available from Panama City. Find the lowest fares based on data from user searches, with prices last updated on 28 January 2026.

Wed 22/410:10
ECP
-
FRA
2 stops24h 55m
United Airlines
Tue 28/417:05
FRA
-
ECP
2 stops35h 54m
United Airlines
Deal found 27/1£432
Wed 4/306:30
ECP
-
LHR
1 stop21h 45m
United Airlines
Thu 12/306:35
LHR
-
ECP
2 stops32h 08m
United Airlines
Deal found 26/1£459
Mon 9/307:05
ECP
-
LHR
1 stop19h 45m
Delta
Mon 16/306:30
LHR
-
ECP
2 stops17h 57m
Delta
Deal found 25/1£459
Thu 5/306:00
ECP
-
LHR
1 stop18h 25m
Delta
Thu 12/306:30
LHR
-
ECP
2 stops17h 57m
Delta
Deal found 27/1£462
Mon 9/313:00
ECP
-
LHR
1 stop16h 15m
United Airlines
Mon 16/318:00
LHR
-
ECP
3 stops48h 14m
United Airlines
Deal found 25/1£468
Wed 22/407:05
ECP
-
LHR
1 stop17h 40m
Delta
Wed 6/509:55
LHR
-
ECP
2 stops19h 17m
Delta
Deal found 26/1£471
Wed 4/309:26
ECP
-
LHR
1 stop16h 24m
KLM
Thu 12/310:45
LHR
-
ECP
1 stop12h 13m
KLM
Deal found 26/1£480
Thu 19/206:30
ECP
-
FRA
1 stop22h 10m
United Airlines
Mon 23/217:10
FRA
-
ECP
2 stops33h 41m
United Airlines
Deal found 25/1£580

Find flights from Panama City within your budget

 
Find flights departing from Panama City that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 28 January 2026. In the last 7 days, Cheapflights users made a total of 858,174 searches

Fly to

Heathrow

Route

Depart

Return

Price

Panama CityFrankfurt am Main

ECP - FRA

ECPFRA

Panama City NW Florida Beaches

Wed 22/4

10:10-18:05

2 stops24h 55m

Frankfurt am Main

Tue 28/4

17:05-21:59

2 stops35h 54m

£432

Panama CityLondon

ECP - LHR

ECPLHR

Panama City NW Florida Beaches

Thu 5/3

10:24-07:55

1 stop15h 31m

London Heathrow

Thu 12/3

06:35-09:43

2 stops32h 08m

£459

Panama CityLondon

ECP - LHR

ECPLHR

Panama City NW Florida Beaches

Mon 9/3

07:05-07:50

1 stop19h 45m

London Heathrow

Mon 16/3

06:30-19:27

2 stops17h 57m

£459

Panama CityLondon

ECP - LHR

ECPLHR

Panama City NW Florida Beaches

Wed 4/3

06:30-10:15

1 stop21h 45m

London Heathrow

Thu 12/3

06:35-09:43

2 stops32h 08m

£461

Panama CityLondon

ECP - LHR

ECPLHR

Panama City NW Florida Beaches

Thu 5/3

06:00-06:25

1 stop18h 25m

London Heathrow

Thu 12/3

06:30-19:27

2 stops17h 57m

£462

Panama CityLondon

ECP - LHR

ECPLHR

Panama City NW Florida Beaches

Wed 11/3

07:05-06:25

1 stop18h 20m

London Heathrow

Wed 18/3

11:30-23:04

2 stops16h 34m

£464

Panama CityLondon

ECP - LHR

ECPLHR

Panama City NW Florida Beaches

Mon 9/3

13:00-10:15

1 stop16h 15m

London Heathrow

Mon 16/3

18:00-13:14

3 stops48h 14m

£468

Panama CityLondon

ECP - LHR

ECPLHR

Panama City NW Florida Beaches

Wed 11/3

14:10-07:55

1 stop12h 45m

London Heathrow

Wed 18/3

12:05-21:57

1 stop14h 52m

£480

Panama CityFrankfurt am Main

ECP - FRA

ECPFRA

Panama City NW Florida Beaches

Thu 19/2

06:30-11:40

1 stop22h 10m

Frankfurt am Main

Mon 23/2

17:10-19:51

2 stops33h 41m

£580

Panama CityLondon

ECP - LHR

ECPLHR

Panama City NW Florida Beaches

Sat 7/3

17:03-07:55

2 stops32h 52m

£295

Flights are sorted by cheapest return flights first.

Deals found on 27/1

Showing 1-10 of 14 results
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Best time to book a flight from Panama City

Have a flexible travel schedule? Discover the best time to fly from Panama City with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama City

Get recent, data-driven insights about flights from Panama City including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Panama City, Florida?

Currently, February is the cheapest month in which you can book a flight from Panama City, Florida (average of £373). Flying from Panama City, Florida in December will prove the most costly (average of £597). There are multiple factors that influence the price of a flight so comparing airlines, departure airports and times can help keep costs down.

What are popular destinations to fly to from Panama City, Florida?

If you’re flying from Panama City, Florida, these routes are more frequently taken by airlines Atlanta (172 flights per day), Dallas (24 flights per day) and Houston (15 flights per day).

Atlanta Hartsfield-Jackson
Atlanta Hartsfield-Jackson
From £589

What is the cheapest place to fly to from Panama City, Florida?

The cheapest city to fly to from Panama City, Florida is Atlanta Hartsfield-Jackson, with prices starting at £589. Explore other affordable destinations below.

Atlanta Hartsfield-Jackson
Atlanta Hartsfield-Jackson
From £589

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Related info for your journey

Access useful and relevant information related to your journey from Panama City. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 28 January 2026.

  • What are the most popular destinations to fly to from Panama City, Florida?

    This month, the top selected destinations from Panama City, Florida are Las Vegas, Dallas/Fort Worth Airport, Denver. Throughout the year, Las Vegas, Denver, New York LaGuardia Airport are some of the top choices made by users flying from Panama City, Florida.

  • What is the cheapest flight from Panama City, Florida to anywhere?

    Users have flown out of Panama City, Florida for as low as £589 to Atlanta (prices may vary depending on the airline and departure time). On average, users have booked flights for £654 to fly from Panama City, Florida.

  • What is the cheapest month to fly from Panama City, Florida?

    At the present moment the cheapest month to fly from Panama City, Florida is currently February; with December being the most expensive. Prices will vary depending on multiple factors such as booking in advance, airline and departure airports and times.

  • How does Cheapflights help users find flights from Panama City?

    Deals for flights from Panama City are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose to your preference, such as price, airport, cabin class, and plenty of other options.

  • Why should you use Cheapflights to find cheap flight tickets from Panama City?

    Millions of users choose and trust Cheapflights to book the best flight deals from Panama City for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.

  • Can Cheapflights find flights from Panama City with no change fees?

    Need flexible booking options for your flight from Panama City ? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

  • Can Cheapflights notify me if prices for flights from Panama City become cheaper?

    Not ready to book yet? You can track prices for flights from Panama City on Cheapflights with our Price Alerts feature and get notified when better prices are available.

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How does Cheapflights help users find flights from Panama City?

Deals for flights from Panama City are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose to your preference, such as price, airport, cabin class, and plenty of other options.

Why should you use Cheapflights to find cheap flight tickets from Panama City?

Millions of users choose and trust Cheapflights to book the best flight deals from Panama City for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.

Can Cheapflights find flights from Panama City with no change fees?

Need flexible booking options for your flight from Panama City ? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

Can Cheapflights notify me if prices for flights from Panama City become cheaper?

Not ready to book yet? You can track prices for flights from Panama City on Cheapflights with our Price Alerts feature and get notified when better prices are available.

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