£145+ Cheap flights from Panama City, Florida

This is the cheapest return flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 14/4. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
ECP — LHR
11 Apr — 18 Apr1
1 adult
1 adult, Economy, 0 bags

Find flights from Panama City

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Cheapest flights from Panama City
Explore the most affordable flight options available from Panama City. Find the lowest fares based on data from user searches, with prices last updated on 12 March 2026.

Wed 22/406:30
ECP
-
LHR
1 stop19h 15m
United Airlines
Wed 6/509:30
LHR
-
ECP
2 stops18h 35m
United Airlines
Deal found 8/3£588
Fri 24/411:01
ECP
-
FRA
1 stop14h 54m
Virgin Atlantic
Fri 1/511:00
FRA
-
ECP
2 stops19h 12m
Virgin Atlantic
Deal found 10/3£606
Tue 5/516:55
ECP
-
LHR
1 stop12h 40m
United Airlines
Thu 28/509:30
LHR
-
ECP
2 stops18h 28m
United Airlines
Deal found 8/3£612
Tue 7/410:29
ECP
-
LHR
1 stop16h 31m
United Airlines
Tue 14/410:50
LHR
-
ECP
2 stops28h 48m
United Airlines
Deal found 9/3£620
Tue 5/511:29
ECP
-
LHR
1 stop14h 11m
United Airlines
Wed 27/510:00
LHR
-
ECP
1 stop16h 01m
United Airlines
Deal found 8/3£623
Fri 24/406:30
ECP
-
FRA
2 stops28h 35m
United Airlines
Fri 1/517:05
FRA
-
ECP
2 stops36h 00m
United Airlines
Deal found 10/3£624
Tue 5/514:14
ECP
-
LHR
2 stops13h 46m
United Airlines
Fri 29/513:40
LHR
-
ECP
1 stop14h 18m
United Airlines
Deal found 7/3£626
Tue 2/609:00
ECP
-
FRA
2 stops20h 05m
United Airlines
Tue 30/609:20
FRA
-
ECP
2 stops31h 24m
United Airlines
Deal found 7/3£833

Find flights from Panama City within your budget

 
Find flights departing from Panama City that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 12 March 2026. In the last 7 days, Cheapflights users made a total of 858,174 searches

Fly to

Route

Depart

Return

Price

Cheapest return flight

Panama CityLondon

ECP - LHR

ECPLHR

Panama City NW Florida Beaches

Wed 22/4

10:19-11:55

1 stop19h 36m

London Heathrow

Wed 6/5

09:30-22:05

2 stops18h 35m

£588

Panama CityLondon

ECP - LHR

ECPLHR

Panama City NW Florida Beaches

Tue 7/4

10:10-11:35

1 stop19h 25m

London Heathrow

Tue 14/4

09:30-21:59

2 stops18h 29m

£588

Panama CityFrankfurt am Main

ECP - FRA

ECPFRA

Panama City NW Florida Beaches

Fri 24/4

11:01-08:55

1 stop14h 54m

Frankfurt am Main

Fri 1/5

11:00-23:12

2 stops19h 12m

£606

Panama CityLondon

ECP - LHR

ECPLHR

Panama City NW Florida Beaches

Tue 5/5

14:14-09:00

1 stop12h 46m

London Heathrow

Thu 28/5

09:30-21:58

2 stops18h 28m

£612
Fastest return journey

Panama CityLondon

ECP - LHR

ECPLHR

Panama City NW Florida Beaches

Tue 5/5

11:29-07:40

1 stop14h 11m

London Heathrow

Wed 27/5

10:00-20:01

1 stop16h 01m

£623

Panama CityLondon

ECP - LHR

ECPLHR

Panama City NW Florida Beaches

Thu 23/4

14:19-06:45

1 stop34h 26m

London Heathrow

Thu 30/4

14:05-13:18

2 stops53h 13m

£632

Panama CityFrankfurt am Main

ECP - FRA

ECPFRA

Panama City NW Florida Beaches

Fri 24/4

10:29-09:55

1 stop16h 26m

Frankfurt am Main

Fri 1/5

13:55-22:05

1 stop15h 10m

£638

Panama CityLondon

ECP - LHR

ECPLHR

Panama City NW Florida Beaches

Wed 29/4

10:19-08:35

2 stops16h 16m

London Heathrow

Wed 20/5

13:40-22:05

1 stop14h 25m

£638

Panama CityLondon

ECP - LHR

ECPLHR

Panama City NW Florida Beaches

Fri 24/4

10:29-06:55

2 stops14h 26m

London Heathrow

Fri 1/5

11:05-22:05

2 stops17h 00m

£696

Panama CityLondon

ECP - LHR

ECPLHR

Panama City NW Florida Beaches

Wed 20/5

14:14-10:00

2 stops37h 46m

London Heathrow

Fri 29/5

10:25-21:58

2 stops17h 33m

£739

Flights are sorted by cheapest return flights first.

Deals found on 7/3

Showing 1-10 of 16 resultsSorted by cheapest first
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Best time to book a flight from Panama City

Have a flexible travel schedule? Discover the best time to fly from Panama City with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama City

Get recent, data-driven insights about flights from Panama City including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Panama City, Florida?

Currently, February is the cheapest month in which you can book a flight from Panama City, Florida (average of £378). Flying from Panama City, Florida in June will prove the most costly (average of £676). There are multiple factors that influence the price of a flight so comparing airlines, departure airports and times can help keep costs down.

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Related info for your journey

Access useful and relevant information related to your journey from Panama City. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 12 March 2026.

  • What are the most popular destinations to fly to from Panama City, Florida?

    This month, the top selected destinations from Panama City, Florida are Washington, D.C. Reagan-National Airport, Denver, New York LaGuardia Airport. Throughout the year, Las Vegas, Denver, New York LaGuardia Airport are some of the top choices made by users flying from Panama City, Florida.

  • What is the cheapest month to fly from Panama City, Florida?

    At the present moment the cheapest month to fly from Panama City, Florida is currently February; with June being the most expensive. Prices will vary depending on multiple factors such as booking in advance, airline and departure airports and times.

  • How does Cheapflights help users find flights from Panama City?

    Deals for flights from Panama City are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose to your preference, such as price, airport, cabin class, and plenty of other options.

  • Why should you use Cheapflights to find cheap flight tickets from Panama City?

    Millions of users choose and trust Cheapflights to book the best flight deals from Panama City for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.

  • Can Cheapflights find flights from Panama City with no change fees?

    Need flexible booking options for your flight from Panama City ? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

  • Can Cheapflights notify me if prices for flights from Panama City become cheaper?

    Not ready to book yet? You can track prices for flights from Panama City on Cheapflights with our Price Alerts feature and get notified when better prices are available.

See more FAQs

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How does Cheapflights help users find flights from Panama City?

Deals for flights from Panama City are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose to your preference, such as price, airport, cabin class, and plenty of other options.

Why should you use Cheapflights to find cheap flight tickets from Panama City?

Millions of users choose and trust Cheapflights to book the best flight deals from Panama City for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.

Can Cheapflights find flights from Panama City with no change fees?

Need flexible booking options for your flight from Panama City ? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

Can Cheapflights notify me if prices for flights from Panama City become cheaper?

Not ready to book yet? You can track prices for flights from Panama City on Cheapflights with our Price Alerts feature and get notified when better prices are available.

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