£187+ Cheap flights from Panama City, Florida

This is the cheapest return flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 25/12. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
ECP — LHR
29 Nov — 6 Dec1
1 adult
1 adult, Economy, 0 bags

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Cheapest flights from Panama City
Explore the most affordable flight options available from Panama City. Find the lowest fares based on data from user searches, with prices last updated on 30 October 2025.

Wed 12/1111:11ECP - LHR
1 stop15h 49mDelta
Wed 19/1111:30LHR - ECP
2 stops17h 07mDelta
Deal found 26/10£448
Sun 9/1106:30ECP - FRA
2 stops22h 35mUnited Airlines
Tue 18/1107:00FRA - ECP
2 stops21h 49mUnited Airlines
Deal found 29/10£450
Sun 9/1109:23ECP - FRA
1 stop16h 17mDelta
Tue 18/1109:50FRA - ECP
1 stop16h 10mDelta
Deal found 28/10£453
Wed 4/313:30ECP - LHR
1 stop10h 55mDelta
Thu 12/306:30LHR - ECP
2 stops21h 12mDelta
Deal found 27/10£481
Thu 27/1106:00ECP - LHR
1 stop18h 25mDelta
Thu 4/1211:30LHR - ECP
2 stops17h 36mDelta
Deal found 28/10£485
Wed 12/1115:00ECP - LHR
1 stop13h 15mUnited Airlines
Wed 19/1112:05LHR - ECP
1 stop15h 44mUnited Airlines
Deal found 26/10£491
Thu 11/1210:00ECP - LHR
2 stops15h 50mVirgin Atlantic
Thu 18/1208:55LHR - ECP
1 stop15h 01mVirgin Atlantic
Deal found 27/10£495
Wed 4/313:30ECP - LHR
1 stop13h 30mKLM
Thu 12/312:30LHR - ECP
1 stop15h 12mKLM
Deal found 28/10£502
Tue 30/1209:52ECP - LHR
1 stop15h 38mUnited Airlines
Fri 9/110:00LHR - ECP
1 stop17h 59mUnited Airlines
Deal found 29/10£509
Thu 5/307:45ECP - LHR
1 stop19h 15mDelta
Thu 12/306:30LHR - ECP
2 stops16h 22mDelta
Deal found 28/10£519
Wed 4/313:01ECP - LHR
1 stop15h 14mUnited Airlines
Thu 12/312:05LHR - ECP
1 stop14h 55mUnited Airlines
Deal found 29/10£521
Fri 27/306:40ECP - FRA
1 stop20h 20mUnited Airlines
Tue 31/308:15FRA - ECP
2 stops18h 51mUnited Airlines
Deal found 29/10£645

Find flights from Panama City within your budget

 
Find flights departing from Panama City that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 30 October 2025. In the last 7 days, Cheapflights users made a total of 858,174 searches

Fly to

Heathrow

Route

Depart

Return

Price

Panama CityFrankfurt am Main

ECP - FRA

ECPFRA

Panama City NW Florida Beaches

Sun 9/11

06:30-12:05

2 stops22h 35m

Frankfurt am Main

Tue 18/11

07:00-21:49

2 stops21h 49m

£450

Panama CityFrankfurt am Main

ECP - FRA

ECPFRA

Panama City NW Florida Beaches

Sun 9/11

09:23-08:40

1 stop16h 17m

Frankfurt am Main

Tue 18/11

06:55-19:00

2 stops19h 05m

£452

Panama CityLondon

ECP - LHR

ECPLHR

Panama City NW Florida Beaches

Wed 4/3

13:30-06:25

1 stop10h 55m

London Heathrow

Thu 12/3

06:30-22:42

2 stops21h 12m

£481

Panama CityLondon

ECP - LHR

ECPLHR

Panama City NW Florida Beaches

Thu 27/11

06:00-06:25

1 stop18h 25m

London Heathrow

Thu 4/12

11:30-23:06

2 stops17h 36m

£485

Panama CityLondon

ECP - LHR

ECPLHR

Panama City NW Florida Beaches

Thu 11/12

17:00-11:40

1 stop12h 40m

London Heathrow

Thu 18/12

08:55-15:43

1 stop12h 48m

£491

Panama CityLondon

ECP - LHR

ECPLHR

Panama City NW Florida Beaches

Wed 12/11

15:00-10:15

1 stop13h 15m

London Heathrow

Wed 19/11

12:05-21:49

1 stop15h 44m

£491

Panama CityLondon

ECP - LHR

ECPLHR

Panama City NW Florida Beaches

Thu 11/12

10:00-07:50

2 stops15h 50m

London Heathrow

Thu 18/12

08:55-17:56

1 stop15h 01m

£495

Panama CityLondon

ECP - LHR

ECPLHR

Panama City NW Florida Beaches

Tue 30/12

09:52-07:30

1 stop15h 38m

London Heathrow

Fri 9/1

09:10-21:59

2 stops18h 49m

£495

Panama CityLondon

ECP - LHR

ECPLHR

Panama City NW Florida Beaches

Wed 4/3

13:30-09:00

1 stop13h 30m

London Heathrow

Thu 12/3

12:30-22:42

1 stop15h 12m

£502

Panama CityLondon

ECP - LHR

ECPLHR

Panama City NW Florida Beaches

Thu 5/3

09:23-09:00

1 stop17h 37m

London Heathrow

Thu 12/3

06:30-19:38

2 stops18h 08m

£519

Flights are sorted by cheapest return flights first.

Deals found on 27/10

Showing 1-10 of 19 results
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Best time to book a flight from Panama City

Have a flexible travel schedule? Discover the best time to fly from Panama City with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama City

Get recent, data-driven insights about flights from Panama City including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Panama City, Florida?

Currently, February is the cheapest month in which you can book a flight from Panama City, Florida (average of £386). Flying from Panama City, Florida in June will prove the most costly (average of £699). There are multiple factors that influence the price of a flight so comparing airlines, departure airports and times can help keep costs down.

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Related info for your journey

Access useful and relevant information related to your journey from Panama City. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 30 October 2025.

  • What are the most popular destinations to fly to from Panama City, Florida?

    This month, the top selected destinations from Panama City, Florida are Boston, Chicago O'Hare Intl Airport, Las Vegas. Throughout the year, Las Vegas, Denver, Nashville are some of the top choices made by users flying from Panama City, Florida.

  • What is the cheapest month to fly from Panama City, Florida?

    At the present moment the cheapest month to fly from Panama City, Florida is currently February; with June being the most expensive. Prices will vary depending on multiple factors such as booking in advance, airline and departure airports and times.

  • How does Cheapflights help users find flights from Panama City?

    Deals for flights from Panama City are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose to your preference, such as price, airport, cabin class, and plenty of other options.

  • Why should you use Cheapflights to find cheap flight tickets from Panama City?

    Millions of users choose and trust Cheapflights to book the best flight deals from Panama City for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.

  • Can Cheapflights find flights from Panama City with no change fees?

    Need flexible booking options for your flight from Panama City ? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

  • Can Cheapflights notify me if prices for flights from Panama City become cheaper?

    Not ready to book yet? You can track prices for flights from Panama City on Cheapflights with our Price Alerts feature and get notified when better prices are available.

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How does Cheapflights help users find flights from Panama City?

Deals for flights from Panama City are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose to your preference, such as price, airport, cabin class, and plenty of other options.

Why should you use Cheapflights to find cheap flight tickets from Panama City?

Millions of users choose and trust Cheapflights to book the best flight deals from Panama City for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.

Can Cheapflights find flights from Panama City with no change fees?

Need flexible booking options for your flight from Panama City ? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

Can Cheapflights notify me if prices for flights from Panama City become cheaper?

Not ready to book yet? You can track prices for flights from Panama City on Cheapflights with our Price Alerts feature and get notified when better prices are available.

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