£176+ Cheap flights from Panama City, Florida

This is the cheapest return flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/2. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
ECP — LHR
13 Dec — 20 Dec1
1 adult
1 adult, Economy, 0 bags

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Cheapest flights from Panama City
Explore the most affordable flight options available from Panama City. Find the lowest fares based on data from user searches, with prices last updated on 13 November 2025.

Wed 4/314:12ECP - LHR
1 stop10h 13mDelta
Thu 12/306:30LHR - ECP
2 stops18h 08mDelta
Deal found 11/11£483
Wed 4/306:30ECP - LHR
1 stop19h 00mUnited Airlines
Thu 12/306:35LHR - ECP
2 stops20h 25mUnited Airlines
Deal found 12/11£501
Wed 4/312:15ECP - LHR
1 stop13h 35mKLM
Thu 12/312:30LHR - ECP
1 stop15h 12mKLM
Deal found 11/11£504
Sun 1/312:15ECP - FRA
1 stop13h 25mVirgin Atlantic
Sat 14/309:50FRA - ECP
1 stop18h 52mVirgin Atlantic
Deal found 12/11£511
Sun 1/308:03ECP - FRA
2 stops16h 47mDelta
Sat 14/310:40FRA - ECP
2 stops27h 40mDelta
Deal found 12/11£515
Thu 5/312:15ECP - LHR
1 stop17h 25mDelta
Thu 12/306:30LHR - ECP
2 stops16h 22mDelta
Deal found 11/11£521
Wed 4/314:12ECP - LHR
1 stop12h 48mMultiple Airlines
Thu 12/310:45LHR - ECP
1 stop12h 07mMultiple Airlines
Deal found 12/11£523
Wed 22/417:30ECP - LHR
1 stop14h 00mDelta
Wed 6/509:55LHR - ECP
2 stops18h 51mDelta
Deal found 12/11£537
Thu 5/314:12ECP - LHR
1 stop12h 48mKLM
Thu 12/312:30LHR - ECP
1 stop15h 12mKLM
Deal found 11/11£542
Fri 27/311:15ECP - FRA
1 stop15h 25mVirgin Atlantic
Tue 31/311:00FRA - ECP
2 stops14h 58mVirgin Atlantic
Deal found 12/11£852
Fri 27/311:15ECP - FRA
2 stops18h 00mDelta
Tue 31/307:00FRA - ECP
2 stops22h 47mDelta
Deal found 10/11£872
Fri 27/316:55ECP - FRA
1 stop12h 45mUnited Airlines
Tue 31/313:55FRA - ECP
1 stop15h 01mUnited Airlines
Deal found 11/11£967

Find flights from Panama City within your budget

 
Find flights departing from Panama City that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 13 November 2025. In the last 7 days, Cheapflights users made a total of 858,174 searches

Fly to

Heathrow

Route

Depart

Return

Price

Panama CityLondon

ECP - LHR

ECPLHR

Panama City NW Florida Beaches

Wed 4/3

14:12-06:25

1 stop10h 13m

London Heathrow

Thu 12/3

06:30-19:38

2 stops18h 08m

£483

Panama CityLondon

ECP - LHR

ECPLHR

Panama City NW Florida Beaches

Wed 4/3

06:30-07:30

1 stop19h 00m

London Heathrow

Thu 12/3

06:35-22:00

2 stops20h 25m

£501

Panama CityLondon

ECP - LHR

ECPLHR

Panama City NW Florida Beaches

Wed 4/3

12:15-07:50

1 stop13h 35m

London Heathrow

Thu 12/3

12:30-22:42

1 stop15h 12m

£504

Panama CityFrankfurt am Main

ECP - FRA

ECPFRA

Panama City NW Florida Beaches

Sun 1/3

12:15-08:40

1 stop13h 25m

Frankfurt am Main

Sat 14/3

09:50-22:42

1 stop18h 52m

£511

Panama CityFrankfurt am Main

ECP - FRA

ECPFRA

Panama City NW Florida Beaches

Sun 1/3

09:26-08:40

1 stop16h 14m

Frankfurt am Main

Sat 14/3

12:00-08:20

2 stops26h 20m

£515

Panama CityLondon

ECP - LHR

ECPLHR

Panama City NW Florida Beaches

Thu 5/3

12:15-11:40

1 stop17h 25m

London Heathrow

Thu 12/3

06:30-17:52

2 stops16h 22m

£521

Panama CityLondon

ECP - LHR

ECPLHR

Panama City NW Florida Beaches

Wed 4/3

14:12-09:00

1 stop12h 48m

London Heathrow

Thu 12/3

10:45-17:52

1 stop12h 07m

£523

Panama CityLondon

ECP - LHR

ECPLHR

Panama City NW Florida Beaches

Wed 22/4

17:30-13:30

1 stop14h 00m

London Heathrow

Wed 6/5

09:55-22:46

2 stops18h 51m

£537

Panama CityLondon

ECP - LHR

ECPLHR

Panama City NW Florida Beaches

Thu 5/3

14:12-09:00

1 stop12h 48m

London Heathrow

Thu 12/3

12:30-22:42

1 stop15h 12m

£542

Panama CityFrankfurt am Main

ECP - FRA

ECPFRA

Panama City NW Florida Beaches

Fri 27/3

11:15-08:40

1 stop15h 25m

Frankfurt am Main

Tue 31/3

11:00-18:58

2 stops14h 58m

£852

Flights are sorted by cheapest return flights first.

Deals found on 11/11

Showing 1-10 of 20 results
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Best time to book a flight from Panama City

Have a flexible travel schedule? Discover the best time to fly from Panama City with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama City

Get recent, data-driven insights about flights from Panama City including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Panama City, Florida?

Currently, February is the cheapest month in which you can book a flight from Panama City, Florida (average of £388). Flying from Panama City, Florida in June will prove the most costly (average of £698). There are multiple factors that influence the price of a flight so comparing airlines, departure airports and times can help keep costs down.

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Related info for your journey

Access useful and relevant information related to your journey from Panama City. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 13 November 2025.

  • What are the most popular destinations to fly to from Panama City, Florida?

    This month, the top selected destinations from Panama City, Florida are Nashville, Las Vegas, New York LaGuardia Airport. Throughout the year, Las Vegas, Denver, Nashville are some of the top choices made by users flying from Panama City, Florida.

  • What is the cheapest month to fly from Panama City, Florida?

    At the present moment the cheapest month to fly from Panama City, Florida is currently February; with June being the most expensive. Prices will vary depending on multiple factors such as booking in advance, airline and departure airports and times.

  • How does Cheapflights help users find flights from Panama City?

    Deals for flights from Panama City are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose to your preference, such as price, airport, cabin class, and plenty of other options.

  • Why should you use Cheapflights to find cheap flight tickets from Panama City?

    Millions of users choose and trust Cheapflights to book the best flight deals from Panama City for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.

  • Can Cheapflights find flights from Panama City with no change fees?

    Need flexible booking options for your flight from Panama City ? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

  • Can Cheapflights notify me if prices for flights from Panama City become cheaper?

    Not ready to book yet? You can track prices for flights from Panama City on Cheapflights with our Price Alerts feature and get notified when better prices are available.

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How does Cheapflights help users find flights from Panama City?

Deals for flights from Panama City are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose to your preference, such as price, airport, cabin class, and plenty of other options.

Why should you use Cheapflights to find cheap flight tickets from Panama City?

Millions of users choose and trust Cheapflights to book the best flight deals from Panama City for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.

Can Cheapflights find flights from Panama City with no change fees?

Need flexible booking options for your flight from Panama City ? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

Can Cheapflights notify me if prices for flights from Panama City become cheaper?

Not ready to book yet? You can track prices for flights from Panama City on Cheapflights with our Price Alerts feature and get notified when better prices are available.

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