£153+ Cheap flights from Panama City, Florida

This is the cheapest return flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 17/10. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
ECP — LHR
18 Oct — 25 Oct1
1 adult
1 adult, Economy

Find flights from Panama City

Cheapest flights from Panama City
Explore the most affordable flight options available from Panama City. Find the lowest fares based on data from user searches, with prices last updated on 18 September 2025.

Mon 17/1113:32ECP - LHR
1 stop10h 53mVirgin Atlantic
Thu 27/1110:00LHR - ECP
2 stops18h 57mVirgin Atlantic
Deal found 17/9£385
Wed 8/1017:32ECP - LHR
1 stop13h 58mKLM
Wed 15/1013:05LHR - ECP
1 stop16h 05mKLM
Deal found 17/9£391
Tue 10/311:15ECP - LHR
2 stops18h 00mDelta
Wed 18/311:30LHR - ECP
2 stops16h 12mDelta
Deal found 17/9£393
Tue 10/313:30ECP - LHR
1 stop14h 30mKLM
Wed 18/312:30LHR - ECP
1 stop12h 08mKLM
Deal found 17/9£396
Wed 8/1013:25ECP - LHR
2 stops15h 20mDelta
Wed 15/1013:05LHR - ECP
1 stop16h 05mDelta
Deal found 17/9£414
Thu 27/1106:00ECP - LHR
1 stop18h 25mDelta
Fri 12/1209:00LHR - ECP
2 stops19h 58mDelta
Deal found 17/9£421
Thu 16/1018:17ECP - LHR
1 stop13h 13mKLM
Thu 23/1015:15LHR - ECP
1 stop13h 55mKLM
Deal found 17/9£427
Fri 31/1009:29ECP - FRA
1 stop17h 11mVirgin Atlantic
Fri 7/1109:50FRA - ECP
1 stop17h 05mVirgin Atlantic
Deal found 16/9£445
Thu 16/1016:25ECP - LHR
2 stops17h 35mScandinavian Airlines
Thu 23/1019:30LHR - ECP
2 stops33h 40mScandinavian Airlines
Deal found 17/9£449
Fri 31/1007:10ECP - FRA
2 stops18h 40mDelta
Fri 7/1110:40FRA - ECP
2 stops19h 30mDelta
Deal found 16/9£449
Thu 16/1013:35ECP - LHR
2 stops15h 10mDelta
Thu 23/1015:15LHR - ECP
1 stop13h 55mDelta
Deal found 17/9£451
Sat 1/1106:00ECP - FRA
2 stops19h 50mDelta
Sat 8/1109:50FRA - ECP
1 stop20h 20mDelta
Deal found 17/9£486

Find flights from Panama City within your budget

 
Find flights departing from Panama City that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 18 September 2025. In the last 7 days, Cheapflights users made a total of 858,174 searches

Fly to

Heathrow

Route

Depart

Return

Price

Panama CityLondon

ECP - LHR

ECPLHR

Panama City NW Florida Beaches

Mon 17/11

13:32-06:25

1 stop10h 53m

London Heathrow

Thu 27/11

10:00-22:57

2 stops18h 57m

£385

Panama CityLondon

ECP - LHR

ECPLHR

Panama City NW Florida Beaches

Tue 10/3

07:45-06:25

1 stop17h 40m

London Heathrow

Wed 18/3

08:55-22:42

2 stops18h 47m

£391

Panama CityLondon

ECP - LHR

ECPLHR

Panama City NW Florida Beaches

Tue 10/3

13:30-09:00

1 stop14h 30m

London Heathrow

Wed 18/3

12:30-19:38

1 stop12h 08m

£396

Panama CityLondon

ECP - LHR

ECPLHR

Panama City NW Florida Beaches

Thu 27/11

07:02-07:05

2 stops18h 03m

London Heathrow

Fri 12/12

08:55-22:58

2 stops20h 03m

£424

Panama CityLondon

ECP - LHR

ECPLHR

Panama City NW Florida Beaches

Thu 27/11

11:11-07:50

1 stop14h 39m

London Heathrow

Fri 12/12

08:55-15:26

1 stop12h 31m

£427

Panama CityLondon

ECP - LHR

ECPLHR

Panama City NW Florida Beaches

Thu 16/10

16:25-11:10

1 stop12h 45m

London Heathrow

Thu 23/10

15:15-23:10

1 stop13h 55m

£427

Panama CityFrankfurt am Main

ECP - FRA

ECPFRA

Panama City NW Florida Beaches

Fri 31/10

09:29-08:40

1 stop17h 11m

Frankfurt am Main

Fri 7/11

09:50-19:55

1 stop17h 05m

£445

Panama CityLondon

ECP - LHR

ECPLHR

Panama City NW Florida Beaches

Thu 16/10

16:25-16:00

2 stops17h 35m

London Heathrow

Thu 23/10

19:30-23:10

2 stops33h 40m

£449

Panama CityFrankfurt am Main

ECP - FRA

ECPFRA

Panama City NW Florida Beaches

Fri 31/10

07:10-07:50

2 stops18h 40m

Frankfurt am Main

Fri 7/11

10:40-23:10

2 stops19h 30m

£449

Panama CityLondon

ECP - LHR

ECPLHR

Panama City NW Florida Beaches

Thu 16/10

13:35-10:45

2 stops15h 10m

London Heathrow

Thu 23/10

15:15-23:10

1 stop13h 55m

£451

Flights are sorted by cheapest return flights first.

Deals found on 15/9

Showing 1-10 of 22 results
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Best time to book a flight from Panama City

Have a flexible travel schedule? Discover the best time to fly from Panama City with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama City

Get recent, data-driven insights about flights from Panama City including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Panama City, Florida?

Currently, September is the cheapest month in which you can book a flight from Panama City, Florida (average of £388). Flying from Panama City, Florida in June will prove the most costly (average of £677). There are multiple factors that influence the price of a flight so comparing airlines, departure airports and times can help keep costs down.

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Related info for your journey

Access useful and relevant information related to your journey from Panama City. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 18 September 2025.

  • What are the most popular destinations to fly to from Panama City, Florida?

    This month, the top selected destinations from Panama City, Florida are Dallas/Fort Worth Airport, Denver, Las Vegas. Throughout the year, Las Vegas, Denver, Nashville are some of the top choices made by users flying from Panama City, Florida.

  • What is the cheapest month to fly from Panama City, Florida?

    At the present moment the cheapest month to fly from Panama City, Florida is currently September; with June being the most expensive. Prices will vary depending on multiple factors such as booking in advance, airline and departure airports and times.

  • How does Cheapflights help users find flights from Panama City?

    Deals for flights from Panama City are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose to your preference, such as price, airport, cabin class, and plenty of other options.

  • Why should you use Cheapflights to find cheap flight tickets from Panama City?

    Millions of users choose and trust Cheapflights to book the best flight deals from Panama City for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.

  • Can Cheapflights find flights from Panama City with no change fees?

    Need flexible booking options for your flight from Panama City ? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

  • Can Cheapflights notify me if prices for flights from Panama City become cheaper?

    Not ready to book yet? You can track prices for flights from Panama City on Cheapflights with our Price Alerts feature and get notified when better prices are available.

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How does Cheapflights help users find flights from Panama City?

Deals for flights from Panama City are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose to your preference, such as price, airport, cabin class, and plenty of other options.

Why should you use Cheapflights to find cheap flight tickets from Panama City?

Millions of users choose and trust Cheapflights to book the best flight deals from Panama City for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.

Can Cheapflights find flights from Panama City with no change fees?

Need flexible booking options for your flight from Panama City ? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

Can Cheapflights notify me if prices for flights from Panama City become cheaper?

Not ready to book yet? You can track prices for flights from Panama City on Cheapflights with our Price Alerts feature and get notified when better prices are available.

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