What day of the week experiences the fewest flight delays on this route?

Sunday tends to have the lowest number of delays on this route, whereas Wednesday has historically faced a higher average of delays compared to other days of the week.

How often are flights from Santiago to La Serena delayed?

About 9% of weekly flights between Santiago and La Serena have experienced delays in the past year, with the average delay time being 86 minutes.

Which airline has the best punctuality record on Santiago to La Serena flights?

Over the past year, Sky Airline have had the lowest number of delays on this route, with just 8% of flights being delayed.

What is the most punctual flight time for Santiago to La Serena flights?

Historically, flights departing in the early afternoon are less likely to be delayed, whereas flights leaving at night tend to experience delays more often.

How long is the flight from Santiago to La Serena?

There are many flights that can get you from Santiago to La Serena in 1h 11m. Fly via JetSMART or Sky Airline to get the fastest option. The distance from Santiago to La Serena is about 241 mi. All flights are typically direct.

In terms of precipitation, rainfall in La Serena ranges from 0.0 - 30.0 inches per month. June is typically the wettest month, when rainfall can reach 30.0 mm. January is typically the driest time to visit La Serena when rainfall is around 0.0 mm.

If weather is an important factor for your trip to La Serena, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 17.0 C. Travellers hoping to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 11.0 C).

What are the most reliable airlines from Santiago to La Serena?

No one likes to see their flight delayed. When booking a flight from Santiago to La Serena consider choosing Iberia (84%), Qantas Airways (79%) or LATAM Airlines (77%) as they are the most reliable in getting you off to your destination on time.

Can I find deals for flights from Santiago to La Serena that include hotel bookings?

Yes. In addition to deals on Santiago to La Serena flights, Cheapflights offers holiday packages that include both flights and hotel.

How can I find direct flights from Santiago to La Serena?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to La Serena.

Can I find deals for business class flights from Santiago to La Serena?

Yes. Cheapflights offers flight deals from Santiago to La Serena by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

£16+ Cheap Flights from Santiago to La Serena

Cheap flight deals from Santiago to La Serena

Enter your travel dates to find the best prices.

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Cheapest flights from Santiago to La Serena
Explore the most affordable flight options available from Santiago to La Serena. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 9 September 2026.

Wed 21/1008:54 -

Nonstop1h 13m

Wed 28/1009:40 -

Nonstop1h 00m

Deal found 6/9£32

Sat 26/1212:21 -

Nonstop1h 09m

Tue 29/1210:38 -

Nonstop1h 03m

Deal found 8/9£34

Thu 24/916:49 -

Nonstop1h 11m

Wed 30/923:43 -

Nonstop1h 00m

Deal found 6/9£35

Fri 25/914:36 -

Nonstop1h 11m

Sun 27/911:55 -

Nonstop1h 00m

Deal found 8/9£37

Fri 2/1010:55 -

Nonstop1h 11m

Sun 4/1010:48 -

Nonstop1h 00m

Deal found 8/9£40

Fri 23/1010:55 -

Nonstop1h 11m

Sun 25/1010:48 -

Nonstop1h 00m

Deal found 8/9£41

Mon 5/1011:20 -

Nonstop1h 10m

Thu 8/1009:23 -

Nonstop1h 00m

Deal found 9/9£41

Tue 22/906:46 -

Nonstop1h 11m

Sat 26/912:39 -

Nonstop1h 00m

Deal found 9/9£42

Mon 21/1210:40 -

Nonstop1h 11m

Thu 31/1221:59 -

Nonstop1h 01m

Deal found 6/9£43

Fri 25/914:36 -

Nonstop1h 11m

Wed 30/923:43 -

Nonstop1h 00m

Deal found 9/9£44

Fri 6/1116:27 -

Nonstop1h 09m

Sun 8/1110:50 -

Nonstop1h 03m

Deal found 7/9£44

Find flight deals from Santiago to La Serena

Round-trip from	£32
One-way from	£16
Popular in	June
Cheapest in	September
Average price	£42

JetSMART
23/10-26/10
Nonstop
2h 11m total
Santiago to La Serena

Search Deals

JetSMART
17/9-31/12
Nonstop
1h 11m total
Santiago to La Serena

Search Deals

Highest demand for flights based on searches. 2% potential increase in price (£1 potential increase over avg. return price).

Search Deals

Cheapest flight prices on average. 2% potential price decrease (£1 potential savings vs. average return price).

Search Deals

Average for round-trip flights in September 2026

Search Deals

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

SantiagoLa Serena

SCL Santiago Arturo Merino Benitez - LSC La Serena La Florida

SCLLSC

Santiago Arturo Merino Benitez

Thu 17/9

22:25-23:36

Nonstop1h 11m

La Serena La Florida

Wed 31/12

00:00-00:00

Nonstop0h 00m

£16

SantiagoLa Serena

SCL Santiago Arturo Merino Benitez - LSC La Serena La Florida

SCLLSC

Santiago Arturo Merino Benitez

Fri 20/11

16:27-17:36

Nonstop1h 09m

La Serena La Florida

Wed 31/12

00:00-00:00

Nonstop0h 00m

£18

SantiagoLa Serena

SCL Santiago Arturo Merino Benitez - LSC La Serena La Florida

SCLLSC

Santiago Arturo Merino Benitez

Fri 2/10

10:55-12:06

Nonstop1h 11m

La Serena La Florida

Wed 31/12

00:00-00:00

Nonstop0h 00m

£22

SantiagoLa Serena

SCL Santiago Arturo Merino Benitez - LSC La Serena La Florida

SCLLSC

Santiago Arturo Merino Benitez

Sat 19/9

17:55-19:06

Nonstop1h 11m

La Serena La Florida

Wed 31/12

00:00-00:00

Nonstop0h 00m

£22

Fastest return journey

SantiagoLa Serena

SCL Santiago Arturo Merino Benitez - LSC La Serena La Florida

SCLLSC

Santiago Arturo Merino Benitez

Wed 13/1

10:00-11:09

Nonstop1h 09m

La Serena La Florida

Wed 31/12

00:00-00:00

Nonstop0h 00m

£24

SantiagoLa Serena

SCL Santiago Arturo Merino Benitez - LSC La Serena La Florida

SCLLSC

Santiago Arturo Merino Benitez

Sun 27/9

18:25-19:36

Nonstop1h 11m

La Serena La Florida

Wed 31/12

00:00-00:00

Nonstop0h 00m

£26

SantiagoLa Serena

SCL Santiago Arturo Merino Benitez - LSC La Serena La Florida

SCLLSC

Santiago Arturo Merino Benitez

Fri 19/2

08:20-09:30

Nonstop1h 10m

La Serena La Florida

Wed 31/12

00:00-00:00

Nonstop0h 00m

£27

SantiagoLa Serena

SCL Santiago Arturo Merino Benitez - LSC La Serena La Florida

SCLLSC

Santiago Arturo Merino Benitez

Mon 21/9

15:47-16:58

Nonstop1h 11m

La Serena La Florida

Wed 31/12

00:00-00:00

Nonstop0h 00m

£28

SantiagoLa Serena

SCL Santiago Arturo Merino Benitez - LSC La Serena La Florida

SCLLSC

Santiago Arturo Merino Benitez

Mon 14/9

16:16-17:27

Nonstop1h 11m

La Serena La Florida

Wed 31/12

00:00-00:00

Nonstop0h 00m

£30

SantiagoLa Serena

SCL Santiago Arturo Merino Benitez - LSC La Serena La Florida

SCLLSC

Santiago Arturo Merino Benitez

Mon 5/10

11:20-12:30

Nonstop1h 10m

La Serena La Florida

Thu 8/10

09:23-10:23

Nonstop1h 00m

£41

Flights are sorted by cheapest return flights first.

Deals found on 5/9

Showing 1-10 of 21 resultsSorted by cheapest first

Best time to book a flight from Santiago to La Serena

Have a flexible travel schedule? Discover the best time to fly to La Serena from Santiago with our price prediction graph.

SCL-LSC

Estimated return price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santiago to La Serena

Prices

Delays

How far ahead should I book a flight from Santiago to La Serena?

The best time to book flights from Santiago to La Serena is 84 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Santiago to La Serena?

Currently, September is the cheapest month in which you can book a flight from Santiago to La Serena (average of £42). Flying from Santiago to La Serena in June is currently the most expensive (average of £54). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SCL to LSC?

When flying from Santiago to La Serena, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

How much does it cost for a return flight from Santiago to La Serena?

Airfare is typical for this route at the moment.

Santiago to La Serena flights typically cost between £32 and £54 in October.
The cheapest return price found within the last 5 days was £32 on Multiple Airlines (21 Oct–28 Oct).

Related info for your journey

How long is the flight from Santiago to La Serena?
There are many flights that can get you from Santiago to La Serena in 1h 11m. Fly via JetSMART or Sky Airline to get the fastest option. The distance from Santiago to La Serena is about 241 mi. All flights are typically direct.
What are the most reliable airlines from Santiago to La Serena?
No one likes to see their flight delayed. When booking a flight from Santiago to La Serena consider choosing Iberia (84%), Qantas Airways (79%) or LATAM Airlines (77%) as they are the most reliable in getting you off to your destination on time.
Can I find deals for flights from Santiago to La Serena that include hotel bookings?
Yes. In addition to deals on Santiago to La Serena flights, Cheapflights offers holiday packages that include both flights and hotel.
How can I find direct flights from Santiago to La Serena?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to La Serena.
Can I find deals for business class flights from Santiago to La Serena?
Yes. Cheapflights offers flight deals from Santiago to La Serena by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Santiago to La Serena?
Currently, September is the cheapest month in which you can book a flight from Santiago to La Serena (average of £42). Flying from Santiago to La Serena in June is currently the most expensive (average of £54). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Why should you use Cheapflights to find cheap flight tickets from Santiago to La Serena?

Cheapflights taps into our reliable network of hundreds of airlines and travel agencies to find the best deals for flights from Santiago to La Serena for you. Better yet — we are completely free to use.

Can Cheapflights find flights from Santiago to La Serena with no change fees?

Need flexible booking options for your flight to La Serena from Santiago? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

Can Cheapflights notify me if prices for flights from Santiago to La Serena become cheaper?

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Cheap flights from Santiago to La Serena from £16

This is the cheapest retur flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 17/9. Fares are subject to change and may not be available on all flights or dates of travel.

Cheap flight deals from Santiago to La Serena

Cheapest flights from Santiago to La SerenaExplore the most affordable flight options available from Santiago to La Serena. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 9 September 2026.

Explore the most affordable flight options available from Santiago to La Serena. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 9 September 2026.

Best flights from Santiago to La SerenaDiscover carefully curated flight deals from Santiago to La Serena that have cost, travel time, and stopovers in mind to ensure you get the best travel experience. Data last updated 9 September 2026.

Discover carefully curated flight deals from Santiago to La Serena that have cost, travel time, and stopovers in mind to ensure you get the best travel experience. Data last updated 9 September 2026.

Direct flights from Santiago to La SerenaExplore direct flight options from Santiago to La Serena based on user searches, and compare prices and availability for your desired travel dates. Data last updated 9 September 2026.

Explore direct flight options from Santiago to La Serena based on user searches, and compare prices and availability for your desired travel dates. Data last updated 9 September 2026.

Last-minute flights from Santiago to La SerenaDiscover last-minute flight deals from Santiago to La Serena. Data last updated 9 September 2026 and is based on user searches.

Discover last-minute flight deals from Santiago to La Serena. Data last updated 9 September 2026 and is based on user searches.

One-way flights from Santiago to La SerenaSearch for one-way flight options from Santiago to La Serena. Find affordable one-way fares based on user searches. Data last updated 9 September 2026.

Search for one-way flight options from Santiago to La Serena. Find affordable one-way fares based on user searches. Data last updated 9 September 2026.

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Best time to book a flight from Santiago to La Serena

Have a flexible travel schedule? Discover the best time to fly to La Serena from Santiago with our price prediction graph.

Cheapflights Insights

How far ahead should I book a flight from Santiago to La Serena?

The best time to book flights from Santiago to La Serena is 84 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Santiago to La Serena?

What is the cheapest time of day to fly from SCL to LSC?

When flying from Santiago to La Serena, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

How much does it cost for a return flight from Santiago to La Serena?

Airfare is typical for this route at the moment.

Santiago to La Serena flights typically cost between £32 and £54 in October.The cheapest return price found within the last 5 days was £32 on Multiple Airlines (21 Oct–28 Oct).

How often are flights from Santiago to La Serena delayed?

About 9% of weekly flights between Santiago and La Serena have experienced delays in the past year, with the average delay time being 86 minutes.

What is the most punctual flight time for Santiago to La Serena flights?

Historically, flights departing in the early afternoon are less likely to be delayed, whereas flights leaving at night tend to experience delays more often.

What day of the week experiences the fewest flight delays on this route?

Sunday tends to have the lowest number of delays on this route, whereas Wednesday has historically faced a higher average of delays compared to other days of the week.

Which airline has the best punctuality record on Santiago to La Serena flights?

Over the past year, Sky Airline have had the lowest number of delays on this route, with just 8% of flights being delayed.

Related info for your journey

How long is the flight from Santiago to La Serena?

What are the most reliable airlines from Santiago to La Serena?

Can I find deals for flights from Santiago to La Serena that include hotel bookings?

How can I find direct flights from Santiago to La Serena?

Can I find deals for business class flights from Santiago to La Serena?

What is the cheapest month to book a flight from Santiago to La Serena?

Browse thousands of different options on Cheapflights for your next trip

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Cheapest flights from Santiago to La Serena
Explore the most affordable flight options available from Santiago to La Serena. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 9 September 2026.

Best flights from Santiago to La Serena
Discover carefully curated flight deals from Santiago to La Serena that have cost, travel time, and stopovers in mind to ensure you get the best travel experience. Data last updated 9 September 2026.

Direct flights from Santiago to La Serena
Explore direct flight options from Santiago to La Serena based on user searches, and compare prices and availability for your desired travel dates. Data last updated 9 September 2026.

Last-minute flights from Santiago to La Serena
Discover last-minute flight deals from Santiago to La Serena. Data last updated 9 September 2026 and is based on user searches.

One-way flights from Santiago to La Serena
Search for one-way flight options from Santiago to La Serena. Find affordable one-way fares based on user searches. Data last updated 9 September 2026.

Santiago to La Serena flights typically cost between £32 and £54 in October.
The cheapest return price found within the last 5 days was £32 on Multiple Airlines (21 Oct–28 Oct).