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Cheap flights from Manchester to Greenville from £381

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 28/7. Fares are subject to change and may not be available on all flights or dates of travel.
MAN — GSP
9 Jul — 16 Jul1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Manchester to Greenville

Enter your travel dates to find the best prices.

Cheapest flights from Manchester to Greenville
Explore the most affordable flight options available from Manchester to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 9 June 2026.

Tue 15/920:05
MAN
-
GSP
2 stops28h 29m
British Airways
Wed 23/907:47
GSP
-
MAN
2 stops21h 03m
British Airways
Deal found 9/6£717
Mon 14/906:55
MAN
-
GSP
2 stops17h 04m
American Airlines
Wed 23/915:32
GSP
-
MAN
2 stops13h 18m
American Airlines
Deal found 9/6£770
Tue 15/913:00
MAN
-
GSP
1 stop15h 00m
Virgin Atlantic
Wed 23/910:03
GSP
-
MAN
1 stop16h 12m
Virgin Atlantic
Deal found 9/6£779
Tue 15/913:00
MAN
-
GSP
1 stop12h 26m
Multiple Airlines
Wed 23/907:47
GSP
-
MAN
2 stops21h 03m
Multiple Airlines
Deal found 9/6£791
Mon 14/906:55
MAN
-
GSP
2 stops15h 58m
American Airlines
Fri 25/915:40
GSP
-
MAN
2 stops13h 10m
American Airlines
Deal found 9/6£800
Sat 4/706:05
MAN
-
GSP
2 stops22h 29m
Lufthansa
Sat 11/711:18
GSP
-
MAN
2 stops17h 32m
Lufthansa
Deal found 5/6£801
Mon 14/913:00
MAN
-
GSP
1 stop33h 36m
Multiple Airlines
Thu 24/918:57
GSP
-
MAN
2 stops14h 03m
Multiple Airlines
Deal found 9/6£805
Mon 14/913:00
MAN
-
GSP
1 stop13h 46m
Delta
Wed 23/907:00
GSP
-
MAN
1 stop19h 15m
Delta
Deal found 9/6£808
Mon 14/913:00
MAN
-
GSP
1 stop26h 58m
Delta
Fri 25/910:03
GSP
-
MAN
1 stop17h 47m
Delta
Deal found 9/6£838
Sat 4/713:15
MAN
-
GSP
1 stop12h 05m
Virgin Atlantic
Sat 11/712:46
GSP
-
MAN
2 stops28h 34m
Virgin Atlantic
Deal found 5/6£846
Fri 3/713:00
MAN
-
GSP
1 stop15h 59m
Virgin Atlantic
Fri 10/710:03
GSP
-
MAN
1 stop17h 47m
Virgin Atlantic
Deal found 5/6£872
Mon 14/906:05
MAN
-
GSP
2 stops18h 00m
Brussels Airlines
Tue 22/915:01
GSP
-
MAN
3 stops25h 49m
Brussels Airlines
Deal found 9/6£879

Find flight deals from Manchester to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from Manchester (MAN) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 9 June 2026.

Round-trip from

£801

One-way from

£381

Popular in

March

Cheapest in

September

Average price

£864
Lufthansa
  • Lufthansa
  • 4/7-11/7
  • 4 total stops
  • 40h 01m total
  • Manchester to Greenville
Search Deals
28/7
  • 28/7
  • 3 total stops
  • 57h 31m total
  • Manchester to Greenville
Search Deals
Highest demand for flights based on searches. 17% potential increase in price (£137 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease (£27 potential savings vs. average return price).
Search Deals
Average for round-trip flights in June 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Manchester to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 9 June 2026.
Use the filters below to find and compare flights from Manchester to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

ManchesterGreenville

MAN - GSP

MANGSP

Manchester

Mon 14/9

13:00-21:46

1 stop13h 46m

Greenville

Wed 23/9

07:00-07:15

1 stop19h 15m

£808

ManchesterGreenville

MAN - GSP

MANGSP

Manchester

Sat 4/7

13:15-20:20

1 stop12h 05m

Greenville

Sat 11/7

17:16-07:15

1 stop32h 59m

£881

ManchesterGreenville

MAN - GSP

MANGSP

Manchester

Fri 3/7

12:10-23:59

2 stops16h 49m

Greenville

Fri 10/7

17:16-13:25

2 stops15h 09m

£899

ManchesterGreenville

MAN - GSP

MANGSP

Manchester

Fri 3/7

13:00-10:43

1 stop26h 43m

Greenville

Fri 10/7

18:52-16:55

2 stops17h 03m

£899

ManchesterGreenville

MAN - GSP

MANGSP

Manchester

Fri 24/7

09:00-09:55

2 stops29h 55m

Greenville

Fri 31/7

10:30-10:25

2 stops18h 55m

£934

ManchesterGreenville

MAN - GSP

MANGSP

Manchester

Mon 14/9

06:05-19:05

3 stops42h 00m

Greenville

Tue 22/9

15:01-21:50

3 stops25h 49m

£969
Fastest return journey

ManchesterGreenville

MAN - GSP

MANGSP

Manchester

Sat 4/7

13:15-23:59

1 stop15h 44m

Greenville

Sat 11/7

12:46-08:20

2 stops14h 34m

£978

ManchesterGreenville

MAN - GSP

MANGSP

Manchester

Tue 21/7

13:00-09:13

1 stop25h 13m

Greenville

Fri 31/7

15:06-13:25

2 stops17h 19m

£997

ManchesterGreenville

MAN - GSP

MANGSP

Manchester

Fri 24/7

20:10-19:49

2 stops28h 39m

Greenville

Tue 28/7

18:32-22:30

2 stops22h 58m

£997

ManchesterGreenville

MAN - GSP

MANGSP

Manchester

Fri 24/7

20:10-19:49

2 stops28h 39m

Greenville

Wed 29/7

14:29-13:15

2 stops17h 46m

£1,014

Flights are sorted by cheapest return flights first.

Deals found on 6/6

Showing 1-10 of 19 resultsSorted by cheapest first
1
2

Best time to book a flight from Manchester to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Manchester with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to Greenville

How much does it cost for a return flight from Manchester to Greenville?

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated 9 June 2026.
Check out reviews from past customers who have flown with Virgin Atlantic from Manchester to Greenville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Virgin Atlantic
7.5
Good
689 reviews
Check prices

Entertainment

7.5

Food

6.9

Crew

8.1

Overall

7.5

Boarding

7.7

Comfort

7.3

Reviews

1 / 20
10.0
Excellent

Edwin,May 2026

LHR - LAX

First time flying with Virgin. It was everything I hoped it would be.
Virgin Atlantic
7.5
Good
689 reviews
Virgin Atlantic
7.5
Good
689 reviews
Check prices

Entertainment

7.5

Food

6.9

Crew

8.1

Overall

7.5

Boarding

7.7

Comfort

7.3

Reviews

1 / 20
10.0
Excellent

Edwin,May 2026

LHR - LAX

First time flying with Virgin. It was everything I hoped it would be.

Related info for your journey

Find useful and relevant information for your journey from Manchester to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Manchester to Greenville?

    Departing from Manchester to Greenville will take you 12h 05m. Airlines will cover a distance of 3936 mi. This flight may include one or multiple stops.

  • What is the cheapest airline to fly from Manchester to Greenville round-trip?

    Virgin Atlantic, at £578, was found to be the cheapest airline from Manchester to Greenville.. Virgin Atlantic is priced at 34% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Manchester to Greenville that include hotel bookings?

    Yes. In addition to deals on Manchester to Greenville flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Manchester to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to Greenville.

  • Can I find deals for business class flights from Manchester to Greenville?

    Yes. Cheapflights offers flight deals from Manchester to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Manchester to Greenville

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Manchester to Greenville

Discover the top airline that operate flights from Manchester to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 9 June 2026.
AirlineCheapestAverageFlexibilityOn-time
Virgin AtlanticCheapest£578Average£798FlexibilityNo cancel feeOn-time72%
Search Virgin Atlantic flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Manchester to Greenville?

Deals for Manchester to Greenville flights are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose better, like price, airport, cabin class, and plenty of other options.

Why should you use Cheapflights to find cheap flight tickets from Manchester to Greenville?

Cheapflights simply makes it quick and affordable to book flights from Manchester to Greenville by bringing together all flight options from hundreds of airlines and agencies online — and put it in one place for you to choose from. Plus, Cheapflights is 100% free to use for all.

Can Cheapflights find flights from Manchester to Greenville with no change fees?

Cheapflights does show flights with no change fees to all users. To see these options for flights from Manchester to Greenville, users can toggle the no change fees filter when performing a flight search.

Can Cheapflights notify me if prices for flights from Manchester to Greenville become cheaper?

Yes, Cheapflights offers price alerts on Manchester to Greenville flights so you can book your travel at the perfect time. Price Alerts can be enabled by clicking the bell icon next to the flight deals above and providing your email address where you want to receive the alerts.

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