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Cheap flights from Manchester to Knoxville from £394

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/7. Fares are subject to change and may not be available on all flights or dates of travel.
MAN — TYS
11 Jul — 18 Jul1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Manchester to Knoxville

Enter your travel dates to find the best prices.

Cheapest flights from Manchester to Knoxville
Explore the most affordable flight options available from Manchester to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 11 June 2026.

Mon 14/910:35
MAN
-
TYS
2 stops18h 24m
Lufthansa
Wed 23/919:20
TYS
-
MAN
2 stops41h 00m
Lufthansa
Deal found 8/6£740
Mon 14/920:50
MAN
-
TYS
2 stops25h 48m
Virgin Atlantic
Wed 23/912:00
TYS
-
MAN
1 stop14h 15m
Virgin Atlantic
Deal found 7/6£756
Fri 20/1109:30
MAN
-
TYS
2 stops19h 07m
United Airlines
Sat 28/1119:35
TYS
-
MAN
2 stops16h 25m
United Airlines
Deal found 7/6£761
Tue 24/1106:10
MAN
-
TYS
2 stops18h 07m
United Airlines
Mon 30/1110:16
TYS
-
MAN
2 stops19h 04m
United Airlines
Deal found 7/6£762
Tue 7/710:35
MAN
-
TYS
2 stops18h 19m
Lufthansa
Tue 21/705:45
TYS
-
MAN
2 stops30h 50m
Lufthansa
Deal found 7/6£767
Thu 17/906:05
MAN
-
TYS
2 stops21h 44m
United Airlines
Mon 21/919:20
TYS
-
MAN
2 stops16h 50m
United Airlines
Deal found 9/6£772

Find flight deals from Manchester to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Manchester (MAN) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 11 June 2026.

Round-trip from

£740

One-way from

£394

Popular in

August

Cheapest in

March

Average price

£875
Lufthansa
  • Lufthansa
  • 14/9-23/9
  • 4 total stops
  • 59h 24m total
  • Manchester to Knoxville
Search Deals
7/7
  • 7/7
  • 3 total stops
  • 45h 09m total
  • Manchester to Knoxville
Search Deals
Highest demand for flights based on searches. 16% potential increase in price (£111 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease (£19 potential savings vs. average return price).
Search Deals
Average for round-trip flights in June 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Manchester to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 11 June 2026.
Use the filters below to find and compare flights from Manchester to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Mon 14/9

10:35-23:59

2 stops18h 24m

Knoxville McGhee Tyson

Wed 23/9

19:20-17:20

2 stops41h 00m

£740

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Fri 20/11

09:30-23:37

2 stops19h 07m

Knoxville McGhee Tyson

Mon 30/11

19:35-17:00

2 stops16h 25m

£761

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Sat 21/11

09:30-23:37

2 stops19h 07m

Knoxville McGhee Tyson

Sat 28/11

19:35-17:00

2 stops16h 25m

£761
Fastest return journey

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Mon 14/9

13:00-23:50

1 stop15h 50m

Knoxville McGhee Tyson

Wed 23/9

11:45-10:10

2 stops17h 25m

£764

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Thu 17/9

06:05-22:49

2 stops21h 44m

Knoxville McGhee Tyson

Mon 21/9

19:20-17:10

2 stops16h 50m

£772
Cheapest one-way

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Wed 22/7

20:20-11:50

3 stops44h 30m

£514

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Mon 29/6

07:45-16:52

3 stops38h 07m

£604

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Tue 30/6

13:25-10:27

2 stops26h 02m

£664

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Wed 22/7

10:40-20:12

1 stop14h 32m

£898

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Tue 30/6

13:00-21:49

1 stop13h 49m

£941

Flights are sorted by cheapest return flights first.

Deals found on 9/6

Showing 1-10 of 12 resultsSorted by cheapest first
1
2

Best time to book a flight from Manchester to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Manchester with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to Knoxville

What is the cheapest month to book a flight from Manchester to Knoxville?

Currently, March is the cheapest month in which you can book a flight from Manchester to Knoxville (average of £583). Flying from Manchester to Knoxville in August is currently the most expensive (average of £1,027). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost for a return flight from Manchester to Knoxville?

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated 11 June 2026.
Read reviews from past customers who have flown with Delta,Virgin Atlantic, andBritish Airways from Manchester to Knoxville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,399 reviews
Check prices

Comfort

7.8

Crew

8.5

Food

7.2

Boarding

8.1

Entertainment

7.8

Overall

7.9

Reviews

1 / 20
8.0
Excellent

Rakshith,May 2026

TPE - SEA

I got middle seat, but it was cheap $340 for Taipei to PDX ,
Delta
7.9
Good
8,399 reviews
Delta
7.9
Good
8,399 reviews
Check prices

Comfort

7.8

Crew

8.5

Food

7.2

Boarding

8.1

Entertainment

7.8

Overall

7.9

Reviews

1 / 20
8.0
Excellent

Rakshith,May 2026

TPE - SEA

I got middle seat, but it was cheap $340 for Taipei to PDX ,
Virgin Atlantic
7.5
Good
689 reviews
Delta
7.9
Good
8,399 reviews
Check prices

Comfort

7.8

Crew

8.5

Food

7.2

Boarding

8.1

Entertainment

7.8

Overall

7.9

Reviews

1 / 20
8.0
Excellent

Rakshith,May 2026

TPE - SEA

I got middle seat, but it was cheap $340 for Taipei to PDX ,
British Airways
6.7
Okay
8,044 reviews
Delta
7.9
Good
8,399 reviews
Check prices

Comfort

7.8

Crew

8.5

Food

7.2

Boarding

8.1

Entertainment

7.8

Overall

7.9

Reviews

1 / 20
8.0
Excellent

Rakshith,May 2026

TPE - SEA

I got middle seat, but it was cheap $340 for Taipei to PDX ,

Related info for your journey

Find useful and relevant information for your journey from Manchester to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Manchester to Knoxville?

    Airlines like Lufthansa and United Airlines fly from Manchester to Knoxville in about 18h 24m. The time it takes to get you to your destination can typically vary by up to 43m. There are 3961 mi between Manchester and Knoxville. Both multi-stop and direct flights can be found to your destination and back.

  • What are the cheapest airlines flying from Manchester to Knoxville round-trip?

    Currently priced at £574, British Airways will fly you from Manchester to Knoxville and back. In addition to British Airways, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from Virgin Atlantic and Delta - these airlines can fly you to your destination from £611 and £710, respectively. You may be able to fly from Manchester to Knoxville for 24% less than the average price by searching for these airlines.

  • Can I find deals for flights from Manchester to Knoxville that include hotel bookings?

    Yes. In addition to deals on Manchester to Knoxville flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Manchester to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to Knoxville.

  • Can I find deals for business class flights from Manchester to Knoxville?

    Yes. Cheapflights offers flight deals from Manchester to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester to Knoxville?

    Currently, March is the cheapest month in which you can book a flight from Manchester to Knoxville (average of £583). Flying from Manchester to Knoxville in August is currently the most expensive (average of £1,027). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee

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Top 3 airlines flying from Manchester to Knoxville

Discover the top 3 airlines that operate flights from Manchester to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 11 June 2026.
AirlineCheapestAverageFlexibilityOn-time
British AirwaysCheapest£574Average£656FlexibilityNo cancel feeOn-time70%
Search British Airways flights
Virgin AtlanticCheapest£611Average£788FlexibilityNo cancel feeOn-time72%
Search Virgin Atlantic flights
DeltaCheapest£710Average£821FlexibilityNo cancel feeOn-timeN/A
Search Delta flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Manchester to Knoxville?

When you search for this flight from Manchester to Knoxville, Cheapflights searches on 900+ travel sites to save you time finding great flight deals online. Additionally, we offer filter features so you can choose a preferred cabin class or airline, see different price ranges, and much more so you can book the flight for you.

Why should you use Cheapflights to find cheap flight tickets from Manchester to Knoxville?

Cheapflights helps you find that perfect flight to Knoxville from Manchester by searching from hundreds of airlines and agencies you know and love. We are also free to use, in case you were wondering!

Can Cheapflights find flights from Manchester to Knoxville with no change fees?

Yes, we can. To see specific flights from Manchester to Knoxville with no change fees, users can toggle flexible booking options after using the search form above to find flights.

Can Cheapflights notify me if prices for flights from Manchester to Knoxville become cheaper?

Yes, Cheapflights offers price alerts on Manchester to Knoxville flights so you can book your travel at the perfect time. Price Alerts can be enabled by clicking the bell icon next to the flight deals above and providing your email address where you want to receive the alerts.

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