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Cheap flights from Santiago to Antofagasta from £20

SCL — ANF
17 Oct — 24 Oct1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Santiago to Antofagasta

Enter your travel dates to find the best prices.

Cheapest flights from Santiago to Antofagasta

Fri 16/1005:57 -
Nonstop2h 05m
Sun 18/1017:25 -
Nonstop1h 57m
Deal found 16/9£39
Thu 1/1006:59 -
Nonstop2h 05m
Sun 4/1013:03 -
Nonstop1h 57m
Deal found 15/9£40
Thu 15/1006:02 -
Nonstop2h 05m
Mon 19/1008:35 -
Nonstop1h 57m
Deal found 15/9£42
Fri 2/1020:24 -
Nonstop2h 02m
Mon 5/1014:34 -
1 stop3h 04m
Deal found 16/9£45
Tue 20/1008:11 -
Nonstop2h 05m
Sat 24/1020:53 -
Nonstop1h 57m
Deal found 15/9£45
Fri 16/1009:34 -
1 stop3h 24m
Sun 18/1020:03 -
Nonstop1h 55m
Deal found 16/9£52
Thu 24/915:24 -
1 stop3h 18m
Sun 27/919:55 -
1 stop3h 15m
Deal found 14/9£53
Mon 12/1005:45 -
Nonstop2h 05m
Mon 19/1008:35 -
Nonstop1h 57m
Deal found 15/9£59
Mon 28/913:59 -
Nonstop2h 05m
Sun 4/1013:03 -
Nonstop1h 57m
Deal found 14/9£60
Thu 15/1008:52 -
Nonstop2h 05m
Tue 20/1017:06 -
Nonstop1h 57m
Deal found 13/9£60
Wed 14/1006:14 -
Nonstop2h 05m
Sat 17/1020:53 -
Nonstop1h 57m
Deal found 16/9£61
Mon 2/1107:59 -
Nonstop2h 04m
Sun 8/1121:03 -
Nonstop1h 55m
Deal found 14/9£62

Find flight deals from Santiago to Antofagasta

Round-trip from

£39

One-way from

£20

Popular in

February

Cheapest in

October

Average price

£71
JetSMART
  • JetSMART
  • 27/11-29/11
  • Nonstop
  • 3h 56m total
  • Santiago to Antofagasta
Search Deals
JetSMART
  • JetSMART
  • 25/10-31/12
  • Nonstop
  • 2h 05m total
  • Santiago to Antofagasta
Search Deals
Highest demand for flights based on searches. 5% potential increase in price (£3 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease (£2 potential savings vs. average return price).
Search Deals
Average for round-trip flights in September 2026
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Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Santiago to Antofagasta that are best for you.

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Price

Cheapest return flight

SantiagoAntofagasta

SCL Santiago Arturo Merino Benitez - ANF Antofagasta Cerro Moreno

SCLANF

Santiago Arturo Merino Benitez

Thu 24/12

14:00-16:04

Nonstop2h 04m

Antofagasta Cerro Moreno

Wed 31/12

00:00-00:00

Nonstop0h 00m

£22

SantiagoAntofagasta

SCL Santiago Arturo Merino Benitez - ANF Antofagasta Cerro Moreno

SCLANF

Santiago Arturo Merino Benitez

Thu 24/9

15:24-18:42

1 stop3h 18m

Antofagasta Cerro Moreno

Wed 31/12

00:00-00:00

Nonstop0h 00m

£22
Fastest return journey

SantiagoAntofagasta

SCL Santiago Arturo Merino Benitez - ANF Antofagasta Cerro Moreno

SCLANF

Santiago Arturo Merino Benitez

Wed 14/10

06:00-08:02

Nonstop2h 02m

Antofagasta Cerro Moreno

Wed 31/12

00:00-00:00

Nonstop0h 00m

£22

SantiagoAntofagasta

SCL Santiago Arturo Merino Benitez - ANF Antofagasta Cerro Moreno

SCLANF

Santiago Arturo Merino Benitez

Tue 5/1

12:37-14:41

Nonstop2h 04m

Antofagasta Cerro Moreno

Wed 31/12

00:00-00:00

Nonstop0h 00m

£30

SantiagoAntofagasta

SCL Santiago Arturo Merino Benitez - ANF Antofagasta Cerro Moreno

SCLANF

Santiago Arturo Merino Benitez

Fri 25/9

09:30-12:48

1 stop3h 18m

Antofagasta Cerro Moreno

Wed 31/12

00:00-00:00

Nonstop0h 00m

£30

SantiagoAntofagasta

SCL Santiago Arturo Merino Benitez - ANF Antofagasta Cerro Moreno

SCLANF

Santiago Arturo Merino Benitez

Fri 16/10

09:34-12:58

1 stop3h 24m

Antofagasta Cerro Moreno

Wed 31/12

00:00-00:00

Nonstop0h 00m

£30

SantiagoAntofagasta

SCL Santiago Arturo Merino Benitez - ANF Antofagasta Cerro Moreno

SCLANF

Santiago Arturo Merino Benitez

Fri 2/10

14:10-16:15

Nonstop2h 05m

Antofagasta Cerro Moreno

Wed 31/12

00:00-00:00

Nonstop0h 00m

£32

SantiagoAntofagasta

SCL Santiago Arturo Merino Benitez - ANF Antofagasta Cerro Moreno

SCLANF

Santiago Arturo Merino Benitez

Wed 23/9

10:14-12:19

Nonstop2h 05m

Antofagasta Cerro Moreno

Wed 31/12

00:00-00:00

Nonstop0h 00m

£36

SantiagoAntofagasta

SCL Santiago Arturo Merino Benitez - ANF Antofagasta Cerro Moreno

SCLANF

Santiago Arturo Merino Benitez

Sun 4/10

18:19-20:21

Nonstop2h 02m

Antofagasta Cerro Moreno

Wed 31/12

00:00-00:00

Nonstop0h 00m

£38

SantiagoAntofagasta

SCL Santiago Arturo Merino Benitez - ANF Antofagasta Cerro Moreno

SCLANF

Santiago Arturo Merino Benitez

Fri 23/10

09:34-12:58

1 stop3h 24m

Antofagasta Cerro Moreno

Wed 31/12

00:00-00:00

Nonstop0h 00m

£39

Flights are sorted by cheapest return flights first.

Deals found on 15/9

Showing 1-10 of 20 resultsSorted by cheapest first
1
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Best time to book a flight from Santiago to Antofagasta

Have a flexible travel schedule? Discover the best time to fly to Antofagasta from Santiago with our price prediction graph.
Estimated return price

Cheapflights Insights

Everything you need to know about your flight from Santiago to Antofagasta

How far ahead should I book a flight from Santiago to Antofagasta?

Booking 66 days in advance of your planned departure date is, on average, the best time to get cheap flights from Santiago to Antofagasta. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Santiago to Antofagasta?

Currently, October is the cheapest month in which you can book a flight from Santiago to Antofagasta (average of £56). Flying from Santiago to Antofagasta in February is currently the most expensive (average of £82). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SCL to ANF?

When flying from Santiago to Antofagasta, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

How much does it cost for a return flight from Santiago to Antofagasta?

Airfare is below average for this route at the moment.

Santiago to Antofagasta flights typically cost between £48 and £80 in October.
The cheapest return price found within the last 5 days was £39 on JetSMART (16 Oct–18 Oct).

Related info for your journey

  • How popular is this Santiago to Antofagasta flight route?

    Within the past month, 4 users have taken a look at flights from Santiago Arturo Merino Benitez to Antofagasta Cerro Moreno.

  • How long is the flight from Santiago to Antofagasta?

    JetSMART can get you from Santiago to Antofagasta in just under 2h 05m. Your travel time will be generally consistent. Santiago and Antofagasta are separated by a distance of 687 mi. Generally, flights for this route are direct.

  • What are the most reliable airlines from Santiago to Antofagasta?

    Consider LATAM Airlines Brasil (100%), Delta (92%) or Iberia (91%) when booking your flight. These represent the most reliable airlines when flying from Santiago to Antofagasta.

  • Can I find deals for flights from Santiago to Antofagasta that include hotel bookings?

    Yes. In addition to deals on Santiago to Antofagasta flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Santiago to Antofagasta?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to Antofagasta.

  • Can I find deals for business class flights from Santiago to Antofagasta?

    Yes. Cheapflights offers flight deals from Santiago to Antofagasta by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santiago to Antofagasta?

    Currently, October is the cheapest month in which you can book a flight from Santiago to Antofagasta (average of £56). Flying from Santiago to Antofagasta in February is currently the most expensive (average of £82). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for Santiago to Antofagasta

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Santiago to Calama flights

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Why should you use Cheapflights to find cheap flight tickets from Santiago to Antofagasta?

By finding flights from multiple airlines and providers at completely no cost, Cheapflights helps millions of users like you annually find the best flights to Antofagasta from Santiago.

Can Cheapflights find flights from Santiago to Antofagasta with no change fees?

Certainly. Search results for flights to Antofagasta from Santiago shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

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Yes! Start tracking prices for Santiago to Antofagasta flights today and get alerted whenever prices for these flights change. To access this feature, click the bell icon next to the flight deals above, which will prompt you for a valid email address to receive your alerts.

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