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Cheap flights from Santiago to Cusco from £99

SCL — CUZ
16 Oct — 23 Oct1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Santiago to Cuzco

Enter your travel dates to find the best prices.

Cheapest flights from Santiago to Cuzco

Fri 30/1006:58 -
1 stop9h 32m
Tue 3/1113:20 -
1 stop7h 15m
Deal found 11/9£194
Sun 20/912:35 -
1 stop9h 15m
Tue 29/920:30 -
2 stops13h 35m
Deal found 11/9£195
Sat 7/1106:07 -
1 stop16h 38m
Sat 14/1110:55 -
1 stop16h 08m
Deal found 14/9£200
Mon 9/1106:07 -
1 stop16h 38m
Sat 14/1110:55 -
1 stop16h 08m
Deal found 11/9£203
Sat 31/1013:38 -
1 stop7h 42m
Sat 7/1113:20 -
1 stop7h 15m
Deal found 16/9£205
Wed 28/1006:07 -
1 stop16h 38m
Wed 4/1110:55 -
1 stop16h 08m
Deal found 13/9£211
Sat 31/1006:02 -
1 stop16h 58m
Fri 6/1107:55 -
1 stop19h 08m
Deal found 14/9£212
Mon 19/1007:10 -
Nonstop3h 30m
Wed 28/1015:30 -
1 stop11h 38m
Deal found 13/9£213
Mon 14/1207:00 -
1 stop11h 50m
Mon 21/1213:20 -
1 stop7h 15m
Deal found 12/9£214
Sun 11/1006:53 -
1 stop16h 17m
Wed 14/1021:50 -
1 stop12h 51m
Deal found 11/9£215

Find flight deals from Santiago to Cuzco

Round-trip from

£183

One-way from

£99

Popular in

July

Cheapest in

November

Average price

£241

Good one-way deal

£228 or less
Sky Airline
  • Sky Airline
  • 31/1-14/2
  • Nonstop
  • 6h 59m total
  • Santiago to Cusco
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JetSMART
  • JetSMART
  • 12/1-31/12
  • 1 total stop
  • 14h 08m total
  • Santiago to Cusco
Search Deals
Highest demand for flights based on searches. 4% potential increase in price (£8 potential increase over avg. return price).
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Cheapest flight prices on average. 1% potential price decrease (£3 potential savings vs. average return price).
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Average for round-trip flights in September 2026
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Price to beat on a one-way flight from Santiago Arturo Merino Benitez to Cusco Velazco Astete.
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Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Santiago to Cusco that are best for you.

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Route

Depart

Return

Price

Cheapest return flight
Fastest return journey

SantiagoCusco

SCL Santiago Arturo Merino Benitez - CUZ Cusco Velazco Astete

SCLCUZ

Santiago Arturo Merino Benitez

Sat 13/2

15:10-16:40

Nonstop3h 30m

Cusco Velazco Astete

Wed 31/12

00:00-02:00

Nonstop0h 00m

£101

SantiagoCusco

SCL Santiago Arturo Merino Benitez - CUZ Cusco Velazco Astete

SCLCUZ

Santiago Arturo Merino Benitez

Sun 22/11

13:33-19:10

1 stop7h 37m

Cusco Velazco Astete

Wed 31/12

00:00-02:00

Nonstop0h 00m

£103

SantiagoCusco

SCL Santiago Arturo Merino Benitez - CUZ Cusco Velazco Astete

SCLCUZ

Santiago Arturo Merino Benitez

Sun 31/1

12:32-06:23

1 stop19h 51m

Cusco Velazco Astete

Wed 31/12

00:00-02:00

Nonstop0h 00m

£105

SantiagoCusco

SCL Santiago Arturo Merino Benitez - CUZ Cusco Velazco Astete

SCLCUZ

Santiago Arturo Merino Benitez

Tue 2/2

11:27-10:23

1 stop24h 56m

Cusco Velazco Astete

Wed 31/12

00:00-02:00

Nonstop0h 00m

£111

SantiagoCusco

SCL Santiago Arturo Merino Benitez - CUZ Cusco Velazco Astete

SCLCUZ

Santiago Arturo Merino Benitez

Mon 8/2

13:30-21:00

1 stop9h 30m

Cusco Velazco Astete

Wed 31/12

00:00-02:00

Nonstop0h 00m

£111

SantiagoCusco

SCL Santiago Arturo Merino Benitez - CUZ Cusco Velazco Astete

SCLCUZ

Santiago Arturo Merino Benitez

Fri 5/2

13:30-21:00

1 stop9h 30m

Cusco Velazco Astete

Wed 31/12

00:00-02:00

Nonstop0h 00m

£137

SantiagoCusco

SCL Santiago Arturo Merino Benitez - CUZ Cusco Velazco Astete

SCLCUZ

Santiago Arturo Merino Benitez

Sun 18/10

20:33-10:05

1 stop15h 32m

Cusco Velazco Astete

Wed 31/12

00:00-02:00

Nonstop0h 00m

£137

SantiagoCusco

SCL Santiago Arturo Merino Benitez - CUZ Cusco Velazco Astete

SCLCUZ

Santiago Arturo Merino Benitez

Mon 9/11

06:07-11:00

1 stop6h 53m

Cusco Velazco Astete

Wed 31/12

00:00-02:00

Nonstop0h 00m

£149

SantiagoCusco

SCL Santiago Arturo Merino Benitez - CUZ Cusco Velazco Astete

SCLCUZ

Santiago Arturo Merino Benitez

Sat 6/2

15:10-16:40

Nonstop3h 30m

Cusco Velazco Astete

Thu 11/2

18:00-23:29

Nonstop3h 29m

£184

SantiagoCusco

SCL Santiago Arturo Merino Benitez - CUZ Cusco Velazco Astete

SCLCUZ

Santiago Arturo Merino Benitez

Mon 8/2

15:10-16:40

Nonstop3h 30m

Cusco Velazco Astete

Sun 14/2

18:00-23:29

Nonstop3h 29m

£184

Flights are sorted by cheapest return flights first.

Deals found on 15/9

Showing 1-10 of 17 resultsSorted by cheapest first
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Best time to book a flight from Santiago to Cuzco

Have a flexible travel schedule? Discover the best time to fly to Cuzco from Santiago with our price prediction graph.
Estimated return price

Cheapflights Insights

Everything you need to know about your flight from Santiago to Cusco

How far ahead should I book a flight from Santiago to Cusco?

The price you pay for your flight from Santiago to Cusco may vary depending on when you book. For the best chance of a lower fare, look to book 75 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Santiago to Cusco?

Currently, November is the cheapest month in which you can book a flight from Santiago to Cusco (average of £190). Flying from Santiago to Cusco in July is currently the most expensive (average of £244). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SCL to CUZ?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Santiago to Cusco as you normally would.

How much does it cost for a return flight from Santiago to Cusco?

Airfare is below average for this route at the moment.

Santiago to Cusco flights typically cost between £214 and £283 in January.
The cheapest return price found within the last 5 days was £183 on Sky Airline (11 Jan–17 Jan).

Related info for your journey

  • How popular is this Santiago to Cusco flight route?

    Flights from Santiago Arturo Merino Benitez to Cusco Velazco Astete have been viewed 3 times in the past calendar month.

  • How long is the flight from Santiago to Cusco?

    Departing from Santiago to Cusco will take you 3h 30m. Santiago and Cusco are separated by a distance of 1373 mi. Most flights are nonstop.

  • Can I find deals for flights from Santiago to Cuzco that include hotel bookings?

    Yes. In addition to deals on Santiago to Cuzco flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Santiago to Cuzco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to Cuzco.

  • Can I find deals for business class flights from Santiago to Cuzco?

    Yes. Cheapflights offers flight deals from Santiago to Cuzco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santiago to Cusco?

    Currently, November is the cheapest month in which you can book a flight from Santiago to Cusco (average of £190). Flying from Santiago to Cusco in July is currently the most expensive (average of £244). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for Santiago to Cuzco

Santiago to Lima flights

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Need flexible booking options for your flight to Cuzco from Santiago? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

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