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Cheap flights from Santiago to Cusco from £128

SCL — CUZ
30 Nov — 7 Dec1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Santiago to Cuzco

Enter your travel dates to find the best prices.

Cheapest flights from Santiago to Cuzco

Thu 26/1106:07 -
1 stop10h 53m
Thu 3/1220:05 -
1 stop9h 56m
Deal found 30/10£205
Sat 12/1208:50 -
Nonstop3h 40m
Sat 19/1208:05 -
1 stop7h 55m
Deal found 28/10£262
Tue 3/1120:45 -
1 stop11h 30m
Tue 10/1106:55 -
1 stop13h 40m
Deal found 30/10£263
Wed 4/1120:55 -
1 stop14h 20m
Tue 10/1106:55 -
1 stop13h 40m
Deal found 29/10£264
Mon 14/1206:07 -
1 stop16h 38m
Mon 21/1210:55 -
1 stop16h 10m
Deal found 30/10£265
Fri 6/1106:07 -
1 stop27h 13m
Thu 12/1110:55 -
1 stop16h 05m
Deal found 26/10£278
Sat 31/1013:38 -
1 stop7h 42m
Sat 7/1113:20 -
1 stop7h 15m
Deal found 26/10£282
Fri 6/1120:45 -
1 stop11h 30m
Fri 13/1119:55 -
1 stop7h 15m
Deal found 29/10£283
Sun 8/1106:07 -
1 stop26h 23m
Thu 12/1110:55 -
1 stop16h 05m
Deal found 26/10£284

Find flight deals from Santiago to Cuzco

Round-trip from

£198

One-way from

£128

Popular in

July

Cheapest in

March

Average price

£241
JetSMART
  • JetSMART
  • 10/3-13/3
  • 2 total stops
  • 18h 16m total
  • Santiago to Cusco
Search Deals
Sky Airline
  • Sky Airline
  • 13/2-31/12
  • Nonstop
  • 3h 30m total
  • Santiago to Cusco
Search Deals
Highest demand for flights based on searches. 2% potential increase in price (£3 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 0% potential price decrease (£2 potential savings vs. average return price).
Search Deals
Average for round-trip flights in October 2026
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Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Santiago to Cusco that are best for you.

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Fly to

Route

Depart

Return

Price

Cheapest return flight
Fastest return journey

SantiagoCusco

SCL Santiago Arturo Merino Benitez - CUZ Cusco Velazco Astete

SCLCUZ

Santiago Arturo Merino Benitez

Sat 13/2

15:10-16:40

Nonstop3h 30m

Cusco Velazco Astete

Wed 31/12

00:00-02:00

Nonstop0h 00m

£128

SantiagoCusco

SCL Santiago Arturo Merino Benitez - CUZ Cusco Velazco Astete

SCLCUZ

Santiago Arturo Merino Benitez

Wed 3/2

15:10-16:40

Nonstop3h 30m

Cusco Velazco Astete

Wed 31/12

00:00-02:00

Nonstop0h 00m

£129

SantiagoCusco

SCL Santiago Arturo Merino Benitez - CUZ Cusco Velazco Astete

SCLCUZ

Santiago Arturo Merino Benitez

Tue 5/1

15:10-16:40

Nonstop3h 30m

Cusco Velazco Astete

Wed 31/12

00:00-02:00

Nonstop0h 00m

£134

SantiagoCusco

SCL Santiago Arturo Merino Benitez - CUZ Cusco Velazco Astete

SCLCUZ

Santiago Arturo Merino Benitez

Sun 22/11

07:00-16:50

1 stop11h 50m

Cusco Velazco Astete

Wed 31/12

00:00-02:00

Nonstop0h 00m

£137

SantiagoCusco

SCL Santiago Arturo Merino Benitez - CUZ Cusco Velazco Astete

SCLCUZ

Santiago Arturo Merino Benitez

Wed 25/11

20:55-09:15

1 stop14h 20m

Cusco Velazco Astete

Wed 31/12

00:00-02:00

Nonstop0h 00m

£138

SantiagoCusco

SCL Santiago Arturo Merino Benitez - CUZ Cusco Velazco Astete

SCLCUZ

Santiago Arturo Merino Benitez

Mon 8/2

20:35-11:30

1 stop16h 55m

Cusco Velazco Astete

Wed 31/12

00:00-02:00

Nonstop0h 00m

£138

SantiagoCusco

SCL Santiago Arturo Merino Benitez - CUZ Cusco Velazco Astete

SCLCUZ

Santiago Arturo Merino Benitez

Fri 13/11

20:45-07:25

1 stop12h 40m

Cusco Velazco Astete

Wed 31/12

00:00-02:00

Nonstop0h 00m

£139

SantiagoCusco

SCL Santiago Arturo Merino Benitez - CUZ Cusco Velazco Astete

SCLCUZ

Santiago Arturo Merino Benitez

Fri 27/11

07:00-16:50

1 stop11h 50m

Cusco Velazco Astete

Wed 31/12

00:00-02:00

Nonstop0h 00m

£146

SantiagoCusco

SCL Santiago Arturo Merino Benitez - CUZ Cusco Velazco Astete

SCLCUZ

Santiago Arturo Merino Benitez

Sun 22/11

06:07-06:30

1 stop26h 23m

Cusco Velazco Astete

Wed 31/12

00:00-02:00

Nonstop0h 00m

£152

SantiagoCusco

SCL Santiago Arturo Merino Benitez - CUZ Cusco Velazco Astete

SCLCUZ

Santiago Arturo Merino Benitez

Tue 15/12

20:35-06:15

1 stop11h 40m

Cusco Velazco Astete

Wed 31/12

00:00-02:00

Nonstop0h 00m

£158

Flights are sorted by cheapest return flights first.

Deals found on 27/10

Showing 1-10 of 16 resultsSorted by cheapest first
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Best time to book a flight from Santiago to Cuzco

Have a flexible travel schedule? Discover the best time to fly to Cuzco from Santiago with our price prediction graph.
Estimated return price

Cheapflights Insights

Everything you need to know about your flight from Santiago to Cusco

How far ahead should I book a flight from Santiago to Cusco?

The price you pay for your flight from Santiago to Cusco may vary depending on when you book. For the best chance of a lower fare, look to book 75 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Santiago to Cusco?

Currently, March is the cheapest month in which you can book a flight from Santiago to Cusco (average of £205). Flying from Santiago to Cusco in July is currently the most expensive (average of £249). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SCL to CUZ?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Santiago to Cusco as you normally would.

How much does it cost for a return flight from Santiago to Cusco?

Airfare is typical for this route at the moment.

Santiago to Cusco flights typically cost between £182 and £250 in March.
The cheapest return price found within the last 5 days was £198 on JetSMART (10 Mar–13 Mar).

Related info for your journey

  • How popular is this Santiago to Cusco flight route?

    Flights from Santiago Arturo Merino Benitez to Cusco Velazco Astete have been viewed 2 times in the past calendar month.

  • How long is the flight from Santiago to Cusco?

    Departing from Santiago to Cusco will take you 3h 30m. Santiago and Cusco are separated by a distance of 1373 mi. Most flights are nonstop.

  • Can I find deals for flights from Santiago to Cuzco that include hotel bookings?

    Yes. In addition to deals on Santiago to Cuzco flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Santiago to Cuzco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to Cuzco.

  • Can I find deals for business class flights from Santiago to Cuzco?

    Yes. Cheapflights offers flight deals from Santiago to Cuzco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santiago to Cusco?

    Currently, March is the cheapest month in which you can book a flight from Santiago to Cusco (average of £205). Flying from Santiago to Cusco in July is currently the most expensive (average of £249). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for Santiago to Cuzco

Santiago to Lima flights

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Need flexible booking options for your flight to Cuzco from Santiago? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

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