Cheap flights from Manchester to Panama from £586

This is the cheapest retur flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/12. Fares are subject to change and may not be available on all flights or dates of travel.
MAN — PTY
16 Nov — 23 Nov1
1 adult
1 adult, Economy

Cheap flight deals from Manchester to Panama

Keep the following information in mind while searching for Manchester to Panama flight deals. Data was last updated 17 October 2025.

Round-trip from

£586

Popular in

December

Cheapest in

March

Average price

£763
American Airlines
  • American Airlines
  • 7/12-8/2
  • 4 total stops
  • 53h 26m total
  • Manchester to Panama
Highest demand for flights based on searches. 12% potential increase in price (£76 potential increase over avg. return price).
Cheapest flight prices on average. 4% potential price decrease (£23 potential savings vs. average return price).
Average for round-trip flights in October 2025

Find flight deals from Manchester to Panama

Enter your travel dates to find the best prices.

Cheapest flights from Manchester to Panama
Explore the most affordable flight options available from Manchester to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 17 October 2025.

Sun 7/1209:40MAN - PTY
2 stops33h 07mAmerican Airlines
Sun 8/216:46PTY - MAN
2 stops20h 19mAmerican Airlines
Deal found 16/10£586
Fri 12/1206:05MAN - PTY
2 stops37h 40mUnited Airlines
Wed 11/210:00PTY - MAN
2 stops21h 20mUnited Airlines
Deal found 16/10£639
Fri 12/1206:05MAN - PTY
2 stops37h 40mUnited Airlines
Fri 13/210:00PTY - MAN
2 stops19h 20mUnited Airlines
Deal found 16/10£640
Tue 9/1223:15MAN - PTY
1 stop25h 35mTurkish Airlines
Wed 11/221:45PTY - MAN
1 stop31h 05mTurkish Airlines
Deal found 16/10£675
Thu 11/1207:45MAN - PTY
2 stops36h 57mAmerican Airlines
Sat 7/217:00PTY - MAN
2 stops21h 05mAmerican Airlines
Deal found 16/10£686
Sun 7/1209:05MAN - PTY
1 stop34h 16mDelta
Thu 12/215:27PTY - MAN
1 stop14h 03mDelta
Deal found 16/10£686
Fri 14/1114:05MAN - PTY
1 stop34h 45mTurkish Airlines
Sun 23/1118:45PTY - MAN
1 stop34h 05mTurkish Airlines
Deal found 16/10£707
Sun 7/1209:05MAN - PTY
1 stop34h 16mDelta
Wed 11/215:27PTY - MAN
2 stops37h 43mDelta
Deal found 16/10£712
Mon 8/1206:00MAN - PTY
2 stops37h 21mDelta
Tue 10/215:27PTY - MAN
1 stop14h 03mDelta
Deal found 16/10£719
Tue 9/1206:00MAN - PTY
2 stops37h 21mDelta
Thu 12/215:27PTY - MAN
1 stop14h 03mDelta
Deal found 16/10£720
Sun 7/1209:05MAN - PTY
1 stop34h 16mDelta
Fri 13/215:27PTY - MAN
2 stops37h 43mDelta
Deal found 16/10£746

Cheapflights Fare Finder

 
Customise your flight search to find flights from Manchester to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 17 October 2025.
Use the filters below to find and compare flights from Manchester to Panama that are best for you.

Fly from

Manchester

Fly to

Panama

Route

Depart

Return

Price

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Wed 11/3

07:50-12:10

2 stops33h 20m

Panama City Tocumen Intl

Mon 16/3

13:50-15:10

2 stops20h 20m

£594

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Sat 14/3

15:35-12:10

2 stops49h 35m

Panama City Tocumen Intl

Fri 20/3

15:50-14:50

2 stops18h 00m

£594

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Wed 11/3

06:10-12:10

2 stops35h 00m

Panama City Tocumen Intl

Thu 19/3

15:50-16:30

2 stops19h 40m

£594

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Tue 10/3

08:55-12:10

2 stops32h 15m

Panama City Tocumen Intl

Wed 18/3

15:50-16:20

2 stops19h 30m

£594

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Wed 11/3

06:00-13:45

2 stops36h 45m

Panama City Tocumen Intl

Mon 16/3

09:30-12:20

2 stops21h 50m

£638

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Thu 12/3

09:25-04:10

2 stops23h 45m

Panama City Tocumen Intl

Mon 16/3

11:35-12:20

2 stops19h 45m

£638

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Fri 12/12

06:05-14:45

2 stops37h 40m

Panama City Tocumen Intl

Tue 10/2

10:00-12:20

2 stops21h 20m

£639

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Fri 12/12

06:05-14:45

2 stops37h 40m

Panama City Tocumen Intl

Thu 12/2

10:00-12:20

2 stops21h 20m

£639

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Fri 12/12

06:05-14:45

2 stops37h 40m

Panama City Tocumen Intl

Sun 8/2

10:00-12:20

2 stops21h 20m

£639

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Fri 12/12

06:05-14:45

2 stops37h 40m

Panama City Tocumen Intl

Fri 13/2

10:00-10:20

2 stops19h 20m

£640

Flights are sorted by cheapest return flights first.

Deals found on 17/10

Showing 1-10 of 12 results
1
2

Best time to book a flight from Manchester to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Manchester with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to Panama

What is the cheapest month to book a flight from Manchester to Panama?

Currently, March is the cheapest month in which you can book a flight from Manchester to Panama (average of £509). Flying from Manchester to Panama in December is currently the most expensive (average of £803). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MAN to PA?

Find hourly flight availability from Manchester to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 17 October 2025.

It’s typically best to fly out from Manchester to Panama at midday. Doing so could potentially save you 23% on the flight price compared to flying in the morning, which is usually more expensive.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated 17 October 2025.
Get a feel of what it's like to fly with KLM, Air France, andUnited Airlines from Manchester to Panama by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Comfort

7.6

Crew

8.4

Overall

7.7

Boarding

7.8

Entertainment

7.1

Food

7.3

Reviews

1 / 20
2.0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.

Comfort

7.6

Crew

8.4

Overall

7.7

Boarding

7.8

Entertainment

7.1

Food

7.3

Reviews

1 / 20
2.0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.

Comfort

7.6

Crew

8.4

Overall

7.7

Boarding

7.8

Entertainment

7.1

Food

7.3

Reviews

1 / 20
2.0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.

Comfort

7.6

Crew

8.4

Overall

7.7

Boarding

7.8

Entertainment

7.1

Food

7.3

Reviews

1 / 20
2.0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.

Comfort

7.6

Crew

8.4

Overall

7.7

Boarding

7.8

Entertainment

7.1

Food

7.3

Reviews

1 / 20
2.0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.

Comfort

7.6

Crew

8.4

Overall

7.7

Boarding

7.8

Entertainment

7.1

Food

7.3

Reviews

1 / 20
2.0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.

Related info for your journey

Find useful and relevant information for your journey from Manchester to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Manchester to Panama?

    Manchester (MAN) is the airport you will fly out of if you book a flight from Manchester to Panama. It is only a 8.9 mi journey to Manchester (MAN) from Manchester’s city center.

  • How long is the flight from Manchester to Panama?

    American Airlines and United Airlines can get you from Manchester to Panama in just under 33h 20m. Your travel time can differ by up to 3h 25m. Airlines will cover a distance of 5182 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Manchester to Panama that include hotel bookings?

    Yes. In addition to deals on Manchester to Panama flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Manchester to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to Panama.

  • Can I find deals for business class flights from Manchester to Panama?

    Yes. Cheapflights offers flight deals from Manchester to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester to Panama?

    Currently, March is the cheapest month in which you can book a flight from Manchester to Panama (average of £509). Flying from Manchester to Panama in December is currently the most expensive (average of £803). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Manchester to Panama

See prices for flight routes from nearby airports that may be better suited for you.

Top 5 airlines flying from Manchester to Panama

Discover the top 5 airlines that operate flights from Manchester to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 17 October 2025.
AirlineCheapestAverageFlexibilityOn-time
Air FranceCheapest£562Average£706FlexibilityNo cancel feeOn-time77%
Search Air France flights
KLMCheapest£576Average£784FlexibilityNo cancel feeOn-time75%
Search KLM flights
United AirlinesCheapest£584Average£695FlexibilityNo cancel feeOn-time69%
Search United Airlines flights
Turkish AirlinesCheapest£625Average£724FlexibilityNo cancel feeOn-time77%
Search Turkish Airlines flights
LufthansaCheapest£628Average£675FlexibilityNo cancel feeOn-time76%
Search Lufthansa flights

Fly with Cheapflights

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How does Cheapflights help users find flights from Manchester to Panama?

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Why should you use Cheapflights to find cheap flight tickets from Manchester to Panama?

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Can Cheapflights find flights from Manchester to Panama with no change fees?

Cheapflights does show flights with no change fees to all users. To see these options for flights from Manchester to Panama, users can toggle the no change fees filter when performing a flight search.

Can Cheapflights notify me if prices for flights from Manchester to Panama become cheaper?

Yes, Cheapflights offers price alerts on Manchester to Panama flights so you can book your travel at the perfect time. Price Alerts can be enabled by clicking the bell icon next to the flight deals above and providing your email address where you want to receive the alerts.

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