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Cheap flights from Manchester to Panama from £678

This is the cheapest retur flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/5. Fares are subject to change and may not be available on all flights or dates of travel.
MAN — PTY
9 May — 16 May1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Manchester to Panama

Enter your travel dates to find the best prices.

Cheapest flights from Manchester to Panama
Explore the most affordable flight options available from Manchester to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 9 April 2026.

Mon 11/508:55
MAN
-
PTY
1 stop13h 55m
KLM
Wed 3/618:50
PTY
-
MAN
1 stop21h 10m
KLM
Deal found 7/4£678
Tue 21/406:05
MAN
-
PTY
2 stops19h 26m
United Airlines
Thu 30/415:30
PTY
-
MAN
2 stops43h 50m
United Airlines
Deal found 6/4£681
Mon 2/1111:50
MAN
-
PTY
2 stops37h 12m
United Airlines
Mon 16/1116:41
PTY
-
MAN
2 stops43h 19m
United Airlines
Deal found 6/4£682
Sat 7/1111:50
MAN
-
PTY
2 stops37h 12m
United Airlines
Sun 22/1110:00
PTY
-
MAN
2 stops19h 20m
United Airlines
Deal found 5/4£683
Mon 27/406:00
MAN
-
PTY
2 stops38h 14m
United Airlines
Mon 11/507:55
PTY
-
MAN
2 stops27h 15m
United Airlines
Deal found 8/4£684
Mon 27/423:30
MAN
-
PTY
2 stops24h 55m
Turkish Airlines
Mon 11/522:20
PTY
-
MAN
1 stop29h 15m
Turkish Airlines
Deal found 8/4£684
Sun 8/1109:05
MAN
-
PTY
1 stop15h 40m
Multiple Airlines
Sun 22/1121:30
PTY
-
MAN
1 stop19h 10m
Multiple Airlines
Deal found 5/4£687
Wed 21/1006:05
MAN
-
PTY
2 stops19h 26m
United Airlines
Fri 6/1108:55
PTY
-
MAN
2 stops27h 05m
United Airlines
Deal found 5/4£689
Tue 20/1006:05
MAN
-
PTY
2 stops19h 26m
United Airlines
Sun 8/1108:55
PTY
-
MAN
2 stops27h 05m
United Airlines
Deal found 5/4£690
Wed 23/906:05
MAN
-
PTY
2 stops19h 26m
United Airlines
Tue 6/1009:45
PTY
-
MAN
2 stops18h 40m
United Airlines
Deal found 6/4£691
Tue 12/505:55
MAN
-
PTY
2 stops40h 17m
United Airlines
Fri 5/609:45
PTY
-
MAN
2 stops18h 40m
United Airlines
Deal found 7/4£692
Tue 14/709:00
MAN
-
PTY
2 stops37h 12m
United Airlines
Fri 31/707:55
PTY
-
MAN
2 stops27h 25m
United Airlines
Deal found 7/4£692

Find flight deals from Manchester to Panama

Keep the following information in mind while searching for Manchester to Panama flight deals. Data was last updated 9 April 2026.

Round-trip from

£678

Popular in

December

Cheapest in

September

Average price

£777
KLM
  • KLM
  • 11/5-3/6
  • 2 total stops
  • 35h 05m total
  • Manchester to Panama
Search Deals
Highest demand for flights based on searches. 4% potential increase in price (£29 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease (£8 potential savings vs. average return price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Manchester to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 9 April 2026.
Use the filters below to find and compare flights from Manchester to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Thu 24/9

05:55-14:14

2 stops38h 19m

Panama City Tocumen Intl

Tue 6/10

09:45-10:25

2 stops18h 40m

£690

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Thu 21/5

06:05-19:31

2 stops19h 26m

Panama City Tocumen Intl

Thu 28/5

09:45-17:20

2 stops25h 35m

£690

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Fri 22/5

05:55-14:14

2 stops38h 19m

Panama City Tocumen Intl

Sun 7/6

09:45-10:25

2 stops18h 40m

£690

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Tue 5/5

06:05-19:31

2 stops19h 26m

Panama City Tocumen Intl

Tue 12/5

15:30-10:10

2 stops36h 40m

£690

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Wed 15/7

09:00-04:04

2 stops25h 04m

Panama City Tocumen Intl

Tue 28/7

15:30-10:15

2 stops36h 45m

£692

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Wed 10/6

06:05-19:31

2 stops19h 26m

Panama City Tocumen Intl

Sun 14/6

09:45-17:20

2 stops25h 35m

£718
Fastest return journey

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Sun 19/7

09:00-04:04

2 stops25h 04m

Panama City Tocumen Intl

Thu 30/7

09:45-10:25

2 stops18h 40m

£718

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Wed 10/6

09:30-20:00

1 stop16h 30m

Panama City Tocumen Intl

Sun 14/6

13:14-07:45

2 stops36h 31m

£729

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Thu 7/5

23:30-18:25

2 stops24h 55m

Panama City Tocumen Intl

Mon 11/5

22:20-12:05

1 stop31h 45m

£737

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Tue 5/5

13:00-17:00

3 stops34h 00m

Panama City Tocumen Intl

Tue 12/5

04:25-11:40

3 stops25h 15m

£739

Flights are sorted by cheapest return flights first.

Deals found on 9/4

Showing 1-10 of 18 resultsSorted by cheapest first
1
2

Best time to book a flight from Manchester to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Manchester with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to Panama

What is the cheapest month to book a flight from Manchester to Panama?

Currently, November is the cheapest month in which you can book a flight from Manchester to Panama (average of £561). Flying from Manchester to Panama in December is currently the most expensive (average of £695). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated 9 April 2026.
Get a feel of what it's like to fly with KLM,Air France, andUnited Airlines from Manchester to Panama by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7.7
Good
1,492 reviews
Check prices

Overall

7.7

Entertainment

7.1

Food

7.3

Crew

8.4

Boarding

7.8

Comfort

7.6

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
KLM
7.7
Good
1,492 reviews
KLM
7.7
Good
1,492 reviews
Check prices

Overall

7.7

Entertainment

7.1

Food

7.3

Crew

8.4

Boarding

7.8

Comfort

7.6

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
Air France
7.4
Good
1,564 reviews
KLM
7.7
Good
1,492 reviews
Check prices

Overall

7.7

Entertainment

7.1

Food

7.3

Crew

8.4

Boarding

7.8

Comfort

7.6

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
United Airlines
7.4
Good
9,555 reviews
KLM
7.7
Good
1,492 reviews
Check prices

Overall

7.7

Entertainment

7.1

Food

7.3

Crew

8.4

Boarding

7.8

Comfort

7.6

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
Turkish Airlines
7.3
Good
4,302 reviews
KLM
7.7
Good
1,492 reviews
Check prices

Overall

7.7

Entertainment

7.1

Food

7.3

Crew

8.4

Boarding

7.8

Comfort

7.6

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
Lufthansa
6.8
Okay
7,900 reviews
KLM
7.7
Good
1,492 reviews
Check prices

Overall

7.7

Entertainment

7.1

Food

7.3

Crew

8.4

Boarding

7.8

Comfort

7.6

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas

Related info for your journey

Find useful and relevant information for your journey from Manchester to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Manchester to Panama?

    Manchester (MAN) is the airport you will fly out of if you book a flight from Manchester to Panama. It is only a 8.9 mi journey to Manchester (MAN) from Manchester’s city center.

  • How long is the flight from Manchester to Panama?

    United Airlines can get you from Manchester to Panama in just under 38h 19m. Your travel time can differ by up to . Airlines will cover a distance of 5182 mi.

  • Can I find deals for flights from Manchester to Panama that include hotel bookings?

    Yes. In addition to deals on Manchester to Panama flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Manchester to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to Panama.

  • Can I find deals for business class flights from Manchester to Panama?

    Yes. Cheapflights offers flight deals from Manchester to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester to Panama?

    Currently, November is the cheapest month in which you can book a flight from Manchester to Panama (average of £561). Flying from Manchester to Panama in December is currently the most expensive (average of £695). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Manchester to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Manchester to Managua flights
Birmingham to Guatemala City flights
Birmingham to San Salvador flights
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Top 5 airlines flying from Manchester to Panama

Discover the top 5 airlines that operate flights from Manchester to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 9 April 2026.
AirlineCheapestAverageFlexibilityOn-time
Air FranceCheapest£562Average£712FlexibilityNo cancel feeOn-time77%
Search Air France flights
United AirlinesCheapest£606Average£697FlexibilityNo cancel feeOn-time69%
Search United Airlines flights
KLMCheapest£608Average£839FlexibilityNo cancel feeOn-time75%
Search KLM flights
LufthansaCheapest£629Average£675FlexibilityNo cancel feeOn-time76%
Search Lufthansa flights
Turkish AirlinesCheapest£651Average£725FlexibilityNo cancel feeOn-time77%
Search Turkish Airlines flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Manchester to Panama?

900+ travel sites are searched through when a user searches for a flight using Cheapflights. From the search interface, users can use filters to choose airlines, airports, flight times, cabin classes and more to their preference. Book your flight to Panama from Manchester today with Cheapflights!

Why should you use Cheapflights to find cheap flight tickets from Manchester to Panama?

Cheapflights helps you find that perfect flight to Panama from Manchester by searching from hundreds of airlines and agencies you know and love. We are also free to use, in case you were wondering!

Can Cheapflights find flights from Manchester to Panama with no change fees?

Cheapflights does show flights with no change fees to all users. To see these options for flights from Manchester to Panama, users can toggle the no change fees filter when performing a flight search.

Can Cheapflights notify me if prices for flights from Manchester to Panama become cheaper?

Yes, Cheapflights offers price alerts on Manchester to Panama flights so you can book your travel at the perfect time. Price Alerts can be enabled by clicking the bell icon next to the flight deals above and providing your email address where you want to receive the alerts.

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