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Cheap flights from Manchester to Panama from £319

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/2. Fares are subject to change and may not be available on all flights or dates of travel.
MAN — PTY
21 Feb — 28 Feb1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Manchester to Panama

Enter your travel dates to find the best prices.

Cheapest flights from Manchester to Panama
Explore the most affordable flight options available from Manchester to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 22 January 2026.

Wed 11/322:25
MAN
-
PTY
2 stops23h 40m
Turkish Airlines
Mon 16/318:45
PTY
-
MAN
1 stop34h 05m
Turkish Airlines
Deal found 20/1£658
Thu 7/505:55
MAN
-
PTY
2 stops40h 17m
United Airlines
Mon 11/509:45
PTY
-
MAN
2 stops18h 40m
United Airlines
Deal found 19/1£663
Tue 10/311:05
MAN
-
PTY
1 stop14h 05m
Air France
Mon 16/322:20
PTY
-
MAN
1 stop30h 50m
Air France
Deal found 20/1£664
Mon 9/306:00
MAN
-
PTY
2 stops39h 07m
United Airlines
Mon 16/315:41
PTY
-
MAN
2 stops39h 39m
United Airlines
Deal found 20/1£667
Thu 29/113:00
MAN
-
PTY
2 stops54h 45m
United Airlines
Mon 2/208:55
PTY
-
MAN
2 stops27h 05m
United Airlines
Deal found 21/1£684
Sat 7/316:50
MAN
-
PTY
2 stops29h 15m
Turkish Airlines
Tue 24/318:45
PTY
-
MAN
1 stop34h 05m
Turkish Airlines
Deal found 20/1£688
Tue 7/410:55
MAN
-
PTY
1 stop14h 50m
Air France
Sat 25/414:20
PTY
-
MAN
1 stop34h 55m
Air France
Deal found 21/1£689
Mon 9/306:00
MAN
-
PTY
2 stops39h 07m
United Airlines
Sun 15/309:30
PTY
-
MAN
2 stops24h 20m
United Airlines
Deal found 20/1£692
Sun 8/1123:15
MAN
-
PTY
1 stop25h 35m
Turkish Airlines
Sun 29/1118:45
PTY
-
MAN
1 stop40h 05m
Turkish Airlines
Deal found 20/1£698
Mon 9/322:25
MAN
-
PTY
2 stops23h 40m
Turkish Airlines
Mon 16/321:45
PTY
-
MAN
1 stop31h 05m
Turkish Airlines
Deal found 20/1£699

Find flight deals from Manchester to Panama

Keep the following information in mind while searching for Manchester to Panama flight deals. Data was last updated 22 January 2026.

Round-trip from

£658

One-way from

£319

Popular in

December

Cheapest in

September

Average price

£773
Turkish Airlines
  • Turkish Airlines
  • 11/3-16/3
  • 3 total stops
  • 57h 45m total
  • Manchester to Panama
Search Deals
10/2
  • 10/2
  • 2 total stops
  • 37h 50m total
  • Manchester to Panama
Search Deals
Highest demand for flights based on searches. 5% potential increase in price (£34 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease (£9 potential savings vs. average return price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Manchester to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 22 January 2026.
Use the filters below to find and compare flights from Manchester to Panama that are best for you.

Fly from

Manchester

Fly to

Panama

Route

Depart

Return

Price

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Thu 7/5

05:55-16:12

2 stops40h 17m

Panama City Tocumen Intl

Mon 11/5

09:45-10:25

2 stops18h 40m

£663

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Mon 9/3

06:00-16:07

2 stops39h 07m

Panama City Tocumen Intl

Mon 16/3

15:41-12:20

2 stops39h 39m

£667

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Thu 12/3

09:25-18:38

2 stops38h 13m

Panama City Tocumen Intl

Mon 16/3

15:41-12:20

2 stops39h 39m

£667

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Sat 7/3

14:05-17:05

2 stops32h 00m

Panama City Tocumen Intl

Wed 25/3

21:45-21:25

1 stop18h 40m

£688

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Tue 10/3

09:05-20:10

2 stops16h 05m

Panama City Tocumen Intl

Mon 16/3

22:20-10:10

1 stop30h 50m

£688

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Tue 7/4

10:55-19:45

1 stop14h 50m

Panama City Tocumen Intl

Sat 25/4

14:20-07:15

1 stop34h 55m

£689

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Tue 10/3

09:25-13:45

2 stops33h 20m

Panama City Tocumen Intl

Sun 15/3

09:30-12:20

2 stops21h 50m

£692

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Mon 9/3

06:00-16:07

2 stops39h 07m

Panama City Tocumen Intl

Sun 15/3

09:30-14:50

2 stops24h 20m

£692

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Thu 12/3

16:50-17:05

2 stops29h 15m

Panama City Tocumen Intl

Mon 16/3

21:45-15:50

1 stop37h 05m

£699

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Fri 13/3

22:25-17:05

2 stops23h 40m

Panama City Tocumen Intl

Mon 16/3

21:45-09:50

1 stop31h 05m

£709

Flights are sorted by cheapest return flights first.

Deals found on 21/1

Showing 1-10 of 15 results
1
2

Best time to book a flight from Manchester to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Manchester with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to Panama

What is the cheapest month to book a flight from Manchester to Panama?

Currently, May is the cheapest month in which you can book a flight from Manchester to Panama (average of £518). Flying from Manchester to Panama in December is currently the most expensive (average of £694). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated 22 January 2026.
Get a feel of what it's like to fly with KLM, Air France, andUnited Airlines from Manchester to Panama by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7.7
Good
1,442 reviews
Check prices

Entertainment

7.1

Boarding

7.8

Food

7.3

Comfort

7.6

Crew

8.4

Overall

7.7

Reviews

1 / 20
10.0
Excellent

Snapyou,Jan 2026

TPA - LHR

Flight operated by Virgin Atlantic - usual high standard service by Virgin.
KLM
7.7
Good
1,442 reviews
KLM
7.7
Good
1,442 reviews
Check prices

Entertainment

7.1

Boarding

7.8

Food

7.3

Comfort

7.6

Crew

8.4

Overall

7.7

Reviews

1 / 20
10.0
Excellent

Snapyou,Jan 2026

TPA - LHR

Flight operated by Virgin Atlantic - usual high standard service by Virgin.
Air France
7.4
Good
1,523 reviews
KLM
7.7
Good
1,442 reviews
Check prices

Entertainment

7.1

Boarding

7.8

Food

7.3

Comfort

7.6

Crew

8.4

Overall

7.7

Reviews

1 / 20
10.0
Excellent

Snapyou,Jan 2026

TPA - LHR

Flight operated by Virgin Atlantic - usual high standard service by Virgin.
United Airlines
7.4
Good
9,192 reviews
KLM
7.7
Good
1,442 reviews
Check prices

Entertainment

7.1

Boarding

7.8

Food

7.3

Comfort

7.6

Crew

8.4

Overall

7.7

Reviews

1 / 20
10.0
Excellent

Snapyou,Jan 2026

TPA - LHR

Flight operated by Virgin Atlantic - usual high standard service by Virgin.
Turkish Airlines
7.3
Good
4,200 reviews
KLM
7.7
Good
1,442 reviews
Check prices

Entertainment

7.1

Boarding

7.8

Food

7.3

Comfort

7.6

Crew

8.4

Overall

7.7

Reviews

1 / 20
10.0
Excellent

Snapyou,Jan 2026

TPA - LHR

Flight operated by Virgin Atlantic - usual high standard service by Virgin.
Lufthansa
6.8
Okay
7,742 reviews
KLM
7.7
Good
1,442 reviews
Check prices

Entertainment

7.1

Boarding

7.8

Food

7.3

Comfort

7.6

Crew

8.4

Overall

7.7

Reviews

1 / 20
10.0
Excellent

Snapyou,Jan 2026

TPA - LHR

Flight operated by Virgin Atlantic - usual high standard service by Virgin.

Related info for your journey

Find useful and relevant information for your journey from Manchester to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Manchester to Panama?

    Manchester (MAN) is the airport you will fly out of if you book a flight from Manchester to Panama. It is only a 8.9 mi journey to Manchester (MAN) from Manchester’s city center.

  • How long is the flight from Manchester to Panama?

    United Airlines and Turkish Airlines can get you from Manchester to Panama in just under 32h. Your travel time can differ by up to 8h 17m. Airlines will cover a distance of 5182 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Manchester to Panama that include hotel bookings?

    Yes. In addition to deals on Manchester to Panama flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Manchester to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to Panama.

  • Can I find deals for business class flights from Manchester to Panama?

    Yes. Cheapflights offers flight deals from Manchester to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester to Panama?

    Currently, May is the cheapest month in which you can book a flight from Manchester to Panama (average of £518). Flying from Manchester to Panama in December is currently the most expensive (average of £694). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Manchester to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Gatwick to San José flights
London City to San José flights
Heathrow to Panama City flights
Stansted to San José flights
Heathrow to Philip S.W.Goldson flights
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Gatwick to Panama City flights
London City to Guatemala City flights
Gatwick to Guatemala City flights
London City to Panama City flights
Stansted to Panama City flights
Heathrow to Managua flights
Manchester to San José flights
Heathrow to Liberia flights
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Gatwick to Philip S.W.Goldson flights
Gatwick to Managua flights
Luton to Panama City flights
London City to Managua flights
Edinburgh to Managua flights
Stansted to Guatemala City flights
Manchester to Panama City flights
Heathrow to San Salvador flights
Newcastle upon Tyne to San José flights
Gatwick to Liberia flights
Heathrow to San Pedro Sula flights
Heathrow to Coxen Hole flights
Gatwick to San Pedro Sula flights
Birmingham to San José flights
Birmingham to Panama City flights
London City to San Salvador flights
London City to San Pedro Sula flights
Manchester to Philip S.W.Goldson flights
Edinburgh to San José flights
London City to Liberia flights
Gatwick to San Salvador flights
Stansted to Managua flights
Manchester to San Salvador flights
Edinburgh to Guatemala City flights
Edinburgh to Panama City flights
Manchester to Managua flights
Manchester to San Pedro Sula flights
Southampton to San Salvador flights
Stansted to San Salvador flights
Newcastle upon Tyne to Panama City flights
Edinburgh to Liberia flights
Birmingham to Philip S.W.Goldson flights

Top 5 airlines flying from Manchester to Panama

Discover the top 5 airlines that operate flights from Manchester to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 22 January 2026.
AirlineCheapestAverageFlexibilityOn-time
Air FranceCheapest£562Average£711FlexibilityNo cancel feeOn-time77%
Search Air France flights
KLMCheapest£578Average£818FlexibilityNo cancel feeOn-time75%
Search KLM flights
United AirlinesCheapest£605Average£694FlexibilityNo cancel feeOn-time69%
Search United Airlines flights
Turkish AirlinesCheapest£625Average£718FlexibilityNo cancel feeOn-time77%
Search Turkish Airlines flights
LufthansaCheapest£628Average£674FlexibilityNo cancel feeOn-time76%
Search Lufthansa flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Manchester to Panama?

900+ travel sites are searched through when a user searches for a flight using Cheapflights. From the search interface, users can use filters to choose airlines, airports, flight times, cabin classes and more to their preference. Book your flight to Panama from Manchester today with Cheapflights!

Why should you use Cheapflights to find cheap flight tickets from Manchester to Panama?

Cheapflights helps you find that perfect flight to Panama from Manchester by searching from hundreds of airlines and agencies you know and love. We are also free to use, in case you were wondering!

Can Cheapflights find flights from Manchester to Panama with no change fees?

Cheapflights does show flights with no change fees to all users. To see these options for flights from Manchester to Panama, users can toggle the no change fees filter when performing a flight search.

Can Cheapflights notify me if prices for flights from Manchester to Panama become cheaper?

Yes, Cheapflights offers price alerts on Manchester to Panama flights so you can book your travel at the perfect time. Price Alerts can be enabled by clicking the bell icon next to the flight deals above and providing your email address where you want to receive the alerts.

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