Cheap flights from Manchester to Panama from £354

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 15/10. Fares are subject to change and may not be available on all flights or dates of travel.
MAN — PTY
15 Oct — 22 Oct1
1 adult
1 adult, Economy

Cheap flight deals from Manchester to Panama

Keep the following information in mind while searching for Manchester to Panama flight deals. Data was last updated 15 September 2025.

Round-trip from

£601

One-way from

£354

Popular in

December

Cheapest in

September

Average price

£649
Lufthansa
  • Lufthansa
  • 21/1-25/1
  • 4 total stops
  • 73h 00m total
  • Manchester to Panama
15/10
  • 15/10
  • 2 total stops
  • 57h 40m total
  • Manchester to Panama
Highest demand for flights based on searches. 13% potential increase in price (£83 potential increase over avg. return price).
Cheapest flight prices on average. 5% potential price decrease (£27 potential savings vs. average return price).
Average for round-trip flights in September 2025

Find flight deals from Manchester to Panama

Cheapest flights from Manchester to Panama
Explore the most affordable flight options available from Manchester to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 15 September 2025.

Sat 15/1117:05MAN - PTY
1 stop32h 05mAir France
Sun 23/1122:20PTY - MAN
1 stop18h 10mAir France
Deal found 14/9£621
Tue 28/1009:25MAN - PTY
2 stops33h 30mLufthansa
Tue 4/1110:00PTY - MAN
2 stops19h 20mLufthansa
Deal found 12/9£622
Fri 14/1111:05MAN - PTY
1 stop14h 05mAir France
Sun 23/1122:20PTY - MAN
1 stop12h 45mAir France
Deal found 14/9£658
Tue 28/1005:50MAN - PTY
1 stop15h 40mMultiple Airlines
Tue 4/1122:20PTY - MAN
1 stop12h 45mMultiple Airlines
Deal found 12/9£674
Fri 14/1110:50MAN - PTY
2 stops35h 15mTurkish Airlines
Sun 23/1118:45PTY - MAN
1 stop34h 05mTurkish Airlines
Deal found 13/9£708
Sat 15/1123:15MAN - PTY
2 stops22h 50mTurkish Airlines
Sun 23/1118:45PTY - MAN
1 stop22h 25mTurkish Airlines
Deal found 14/9£718
Fri 14/1106:05MAN - PTY
2 stops29h 08mUnited Airlines
Sun 23/1112:04PTY - MAN
2 stops23h 56mUnited Airlines
Deal found 13/9£731
Sat 15/1105:50MAN - PTY
2 stops19h 09mDelta
Sun 23/1108:05PTY - MAN
2 stops27h 00mDelta
Deal found 13/9£745

Cheapflights Fare Finder

 
Customise your flight search to find flights from Manchester to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 15 September 2025.
Use the filters below to find and compare flights from Manchester to Panama that are best for you.

Fly from

Manchester

Fly to

Panama

Route

Depart

Return

Price

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Sun 8/2

06:00-14:45

2 stops37h 45m

Panama City Tocumen Intl

Tue 24/2

15:35-12:20

2 stops39h 45m

£619

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Tue 6/1

06:00-13:55

2 stops36h 55m

Panama City Tocumen Intl

Fri 16/1

10:00-17:00

2 stops26h 00m

£625

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Mon 5/1

06:10-13:55

2 stops36h 45m

Panama City Tocumen Intl

Thu 15/1

10:00-10:20

2 stops19h 20m

£627

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Mon 5/1

06:10-13:55

2 stops36h 45m

Panama City Tocumen Intl

Sat 31/1

23:55-17:00

2 stops36h 05m

£627

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Wed 21/1

18:20-19:45

1 stop30h 25m

Panama City Tocumen Intl

Sun 25/1

21:30-17:40

1 stop15h 10m

£633

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Sun 8/2

13:40-19:55

1 stop35h 15m

Panama City Tocumen Intl

Tue 24/2

15:27-10:30

1 stop14h 03m

£652

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Wed 15/10

16:20-20:00

2 stops57h 40m

£354

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Thu 1/1

23:15-17:05

2 stops22h 50m

£666

Flights are sorted by cheapest return flights first.

Deals found on 14/9

Best time to book a flight from Manchester to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Manchester with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to Panama

What is the cheapest month to book a flight from Manchester to Panama?

Currently, April is the cheapest month in which you can book a flight from Manchester to Panama (average of £763). Flying from Manchester to Panama in December is currently the most expensive (average of £1,051). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MAN to PA?

Find hourly flight availability from Manchester to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 15 September 2025.

When flying from Manchester to Panama, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated 15 September 2025.
Get a feel of what it's like to fly with KLM, Air France, andUnited Airlines from Manchester to Panama by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Boarding

7.8

Crew

8.4

Food

7.3

Overall

7.8

Entertainment

7.2

Comfort

7.7

Reviews

1 / 20
4.0
Okay

Mark,Sept 2025

AMS - BHX

Crew and snacks were good, boarding wasn't great as busses were used rather than boarding tunnels. Also endured a one hour delay.

Boarding

7.8

Crew

8.4

Food

7.3

Overall

7.8

Entertainment

7.2

Comfort

7.7

Reviews

1 / 20
4.0
Okay

Mark,Sept 2025

AMS - BHX

Crew and snacks were good, boarding wasn't great as busses were used rather than boarding tunnels. Also endured a one hour delay.

Boarding

7.8

Crew

8.4

Food

7.3

Overall

7.8

Entertainment

7.2

Comfort

7.7

Reviews

1 / 20
4.0
Okay

Mark,Sept 2025

AMS - BHX

Crew and snacks were good, boarding wasn't great as busses were used rather than boarding tunnels. Also endured a one hour delay.

Boarding

7.8

Crew

8.4

Food

7.3

Overall

7.8

Entertainment

7.2

Comfort

7.7

Reviews

1 / 20
4.0
Okay

Mark,Sept 2025

AMS - BHX

Crew and snacks were good, boarding wasn't great as busses were used rather than boarding tunnels. Also endured a one hour delay.

Boarding

7.8

Crew

8.4

Food

7.3

Overall

7.8

Entertainment

7.2

Comfort

7.7

Reviews

1 / 20
4.0
Okay

Mark,Sept 2025

AMS - BHX

Crew and snacks were good, boarding wasn't great as busses were used rather than boarding tunnels. Also endured a one hour delay.

Boarding

7.8

Crew

8.4

Food

7.3

Overall

7.8

Entertainment

7.2

Comfort

7.7

Reviews

1 / 20
4.0
Okay

Mark,Sept 2025

AMS - BHX

Crew and snacks were good, boarding wasn't great as busses were used rather than boarding tunnels. Also endured a one hour delay.

Related info for your journey

Find useful and relevant information for your journey from Manchester to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Manchester to Panama?

    Manchester (MAN) is the airport you will fly out of if you book a flight from Manchester to Panama. It is only a 8.9 mi journey to Manchester (MAN) from Manchester’s city center.

  • How long is the flight from Manchester to Panama?

    United Airlines and Lufthansa can get you from Manchester to Panama in just under 36h 55m. Your travel time can differ by up to 50m. Airlines will cover a distance of 5182 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Manchester to Panama that include hotel bookings?

    Yes. In addition to deals on Manchester to Panama flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Manchester to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to Panama.

  • Can I find deals for business class flights from Manchester to Panama?

    Yes. Cheapflights offers flight deals from Manchester to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester to Panama?

    Currently, April is the cheapest month in which you can book a flight from Manchester to Panama (average of £763). Flying from Manchester to Panama in December is currently the most expensive (average of £1,051). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Manchester to Panama

See prices for flight routes from nearby airports that may be better suited for you.

Top 5 airlines flying from Manchester to Panama

Discover the top 5 airlines that operate flights from Manchester to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 15 September 2025.
AirlineCheapestAverageFlexibilityOn-time
Air FranceCheapest£556Average£699FlexibilityNo cancel feeOn-time77%
Search Air France flights
KLMCheapest£573Average£783FlexibilityNo cancel feeOn-time75%
Search KLM flights
United AirlinesCheapest£579Average£691FlexibilityNo cancel feeOn-time69%
Search United Airlines flights
Turkish AirlinesCheapest£619Average£988FlexibilityNo cancel feeOn-time77%
Search Turkish Airlines flights
LufthansaCheapest£622Average£668FlexibilityNo cancel feeOn-time76%
Search Lufthansa flights

Fly with Cheapflights

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How does Cheapflights help users find flights from Manchester to Panama?

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Can Cheapflights find flights from Manchester to Panama with no change fees?

Cheapflights does show flights with no change fees to all users. To see these options for flights from Manchester to Panama, users can toggle the no change fees filter when performing a flight search.

Can Cheapflights notify me if prices for flights from Manchester to Panama become cheaper?

Yes, Cheapflights offers price alerts on Manchester to Panama flights so you can book your travel at the perfect time. Price Alerts can be enabled by clicking the bell icon next to the flight deals above and providing your email address where you want to receive the alerts.

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