Find flights
When to book
Airlines
FAQs

Cheap flights from Manchester to Panama from £350

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 25/11. Fares are subject to change and may not be available on all flights or dates of travel.
MAN — PTY
14 דצמ' — 21 דצמ'1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Manchester to Panama

Keep the following information in mind while searching for Manchester to Panama flight deals. Data was last updated 14 נובמבר 2025.

Round-trip from

£594

One-way from

£350

Popular in

December

Cheapest in

March

Average price

£725
American Airlines
  • American Airlines
  • 20/3-24/3
  • 4 total stops
  • 57h 10m total
  • Manchester to Panama
Search Deals
25/11
  • 25/11
  • 2 total stops
  • 34h 45m total
  • Manchester to Panama
Search Deals
Highest demand for flights based on searches. 9% potential increase in price (£56 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease (£16 potential savings vs. average return price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Find flight deals from Manchester to Panama

Enter your travel dates to find the best prices.

Cheapest flights from Manchester to Panama
Explore the most affordable flight options available from Manchester to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 14 נובמבר 2025.

ו' 5/1206:05MAN - PTY
2 stops36h 50mLufthansa
א' 14/1210:00PTY - MAN
2 stops19h 20mLufthansa
Deal found 12/11£686
ו' 5/1207:50MAN - PTY
2 stops34h 57mAmerican Airlines
א' 14/1216:43PTY - MAN
2 stops20h 22mAmerican Airlines
Deal found 11/11£793
ו' 5/1213:25MAN - PTY
1 stop35h 34mMultiple Airlines
א' 14/1218:45PTY - MAN
1 stop32h 35mMultiple Airlines
Deal found 12/11£817
ש' 15/1106:10MAN - PTY
2 stops29h 03mUnited Airlines
א' 23/1109:11PTY - MAN
2 stops26h 49mUnited Airlines
Deal found 11/11£837
ו' 14/1106:10MAN - PTY
2 stops29h 03mUnited Airlines
א' 23/1109:11PTY - MAN
2 stops26h 49mUnited Airlines
Deal found 12/11£853
ב' 15/1213:00MAN - PTY
2 stops58h 49mUnited Airlines
ב' 22/1216:41PTY - MAN
2 stops58h 59mUnited Airlines
Deal found 11/11£859
ו' 5/1219:40MAN - PTY
2 stops29h 19mAir France
א' 14/1222:20PTY - MAN
1 stop18h 10mAir France
Deal found 12/11£860

Cheapflights Fare Finder

 
Customise your flight search to find flights from Manchester to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 14 נובמבר 2025.
Use the filters below to find and compare flights from Manchester to Panama that are best for you.

Fly from

Manchester

Fly to

Panama

Route

Depart

Return

Price

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

ו' 20/3

07:50-14:20

2 stops35h 30m

Panama City Tocumen Intl

ג' 24/3

13:50-16:30

2 stops21h 40m

£594

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

א' 8/3

08:55-12:10

2 stops32h 15m

Panama City Tocumen Intl

ג' 17/3

13:50-17:35

2 stops22h 45m

£596

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

ב' 9/3

16:20-12:10

2 stops48h 50m

Panama City Tocumen Intl

א' 15/3

15:50-15:35

2 stops18h 45m

£596

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

ג' 10/3

09:40-12:10

2 stops31h 30m

Panama City Tocumen Intl

א' 15/3

15:50-15:35

2 stops18h 45m

£596

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

ב' 9/3

16:20-12:10

2 stops48h 50m

Panama City Tocumen Intl

ב' 16/3

15:50-15:10

2 stops18h 20m

£596

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

ג' 10/3

14:45-12:10

2 stops50h 25m

Panama City Tocumen Intl

ג' 17/3

13:50-18:45

2 stops23h 55m

£596

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

ה' 12/3

08:50-12:10

2 stops32h 20m

Panama City Tocumen Intl

א' 15/3

15:50-15:35

2 stops18h 45m

£596

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

ד' 11/3

14:50-12:10

2 stops50h 20m

Panama City Tocumen Intl

ג' 17/3

13:50-17:35

2 stops22h 45m

£596

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

א' 8/3

07:55-12:10

2 stops33h 15m

Panama City Tocumen Intl

ש' 14/3

15:50-19:05

2 stops22h 15m

£696

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

ג' 10/3

09:40-12:10

2 stops31h 30m

Panama City Tocumen Intl

ו' 13/3

13:50-16:35

2 stops21h 45m

£696

Flights are sorted by cheapest return flights first.

Deals found on 11/11

Showing 1-10 of 16 results
1
2

Best time to book a flight from Manchester to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Manchester with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to Panama

What is the cheapest month to book a flight from Manchester to Panama?

Currently, March is the cheapest month in which you can book a flight from Manchester to Panama (average of £519). Flying from Manchester to Panama in December is currently the most expensive (average of £708). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MAN to PA?

Find hourly flight availability from Manchester to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 14 נובמבר 2025.

It’s typically best to fly out from Manchester to Panama at midday. Doing so could potentially save you 23% on the flight price compared to flying in the morning, which is usually more expensive.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated 14 נובמבר 2025.
Get a feel of what it's like to fly with KLM, Air France, andUnited Airlines from Manchester to Panama by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7.7
Good
1,410 reviews
Check prices

Comfort

7.7

Overall

7.7

Crew

8.4

Boarding

7.8

Food

7.3

Entertainment

7.1

Reviews

1 / 20
2.0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.
KLM
7.7
Good
1,410 reviews
KLM
7.7
Good
1,410 reviews
Check prices

Comfort

7.7

Overall

7.7

Crew

8.4

Boarding

7.8

Food

7.3

Entertainment

7.1

Reviews

1 / 20
2.0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.
Air France
7.4
Good
1,487 reviews
KLM
7.7
Good
1,410 reviews
Check prices

Comfort

7.7

Overall

7.7

Crew

8.4

Boarding

7.8

Food

7.3

Entertainment

7.1

Reviews

1 / 20
2.0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.
United Airlines
7.4
Good
9,016 reviews
KLM
7.7
Good
1,410 reviews
Check prices

Comfort

7.7

Overall

7.7

Crew

8.4

Boarding

7.8

Food

7.3

Entertainment

7.1

Reviews

1 / 20
2.0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.
Lufthansa
6.8
Okay
7,572 reviews
KLM
7.7
Good
1,410 reviews
Check prices

Comfort

7.7

Overall

7.7

Crew

8.4

Boarding

7.8

Food

7.3

Entertainment

7.1

Reviews

1 / 20
2.0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.

Related info for your journey

Find useful and relevant information for your journey from Manchester to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Manchester to Panama?

    Manchester (MAN) is the airport you will fly out of if you book a flight from Manchester to Panama. It is only a 8.9 mi journey to Manchester (MAN) from Manchester’s city center.

  • How long is the flight from Manchester to Panama?

    American Airlines can get you from Manchester to Panama in just under 35h 30m. Your travel time can differ by up to . Airlines will cover a distance of 5182 mi.

  • Can I find deals for flights from Manchester to Panama that include hotel bookings?

    Yes. In addition to deals on Manchester to Panama flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Manchester to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to Panama.

  • Can I find deals for business class flights from Manchester to Panama?

    Yes. Cheapflights offers flight deals from Manchester to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester to Panama?

    Currently, March is the cheapest month in which you can book a flight from Manchester to Panama (average of £519). Flying from Manchester to Panama in December is currently the most expensive (average of £708). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Manchester to Panama

See prices for flight routes from nearby airports that may be better suited for you.
Heathrow to San José flights
Gatwick to San José flights
London City to San José flights
Heathrow to Panama City flights
Gatwick to Panama City flights
Stansted to San José flights
Heathrow to Guatemala City flights
London City to Panama City flights
Luton to San José flights
Gatwick to Guatemala City flights
Heathrow to Philip S.W.Goldson flights
London City to Guatemala City flights
Stansted to Panama City flights
Manchester to San José flights
Heathrow to Managua flights
Manchester to Guatemala City flights
Manchester to Panama City flights
Luton to Panama City flights
Gatwick to Managua flights
Heathrow to San Salvador flights
Gatwick to Philip S.W.Goldson flights
Edinburgh to San José flights
Heathrow to Liberia flights
London City to Managua flights
Stansted to Guatemala City flights
Birmingham to San José flights
Newcastle upon Tyne to San José flights
Gatwick to San Salvador flights
London City to San Salvador flights
Gatwick to Liberia flights
Heathrow to Coxen Hole flights
Heathrow to San Pedro Sula flights
London City to Liberia flights
Manchester to Managua flights
Manchester to Philip S.W.Goldson flights
London City to San Pedro Sula flights
Southampton to San José flights
Gatwick to San Pedro Sula flights
Birmingham to Philip S.W.Goldson flights
Birmingham to Guatemala City flights
Newcastle upon Tyne to Panama City flights
Edinburgh to Guatemala City flights
Stansted to San Salvador flights
Birmingham to Panama City flights
Manchester to San Salvador flights
Edinburgh to Philip S.W.Goldson flights
Gatwick to Tegucigalpa flights
Birmingham to San Salvador flights
Leeds to Panama City flights

Top 4 airlines flying from Manchester to Panama

Discover the top 4 airlines that operate flights from Manchester to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 14 נובמבר 2025.
AirlineCheapestAverageFlexibilityOn-time
Air FranceCheapest£573Average£721FlexibilityNo cancel feeOn-time77%
Search Air France flights
KLMCheapest£585Average£798FlexibilityNo cancel feeOn-time75%
Search KLM flights
United AirlinesCheapest£597Average£709FlexibilityNo cancel feeOn-time69%
Search United Airlines flights
LufthansaCheapest£641Average£688FlexibilityNo cancel feeOn-time76%
Search Lufthansa flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Manchester to Panama?

900+ travel sites are searched through when a user searches for a flight using Cheapflights. From the search interface, users can use filters to choose airlines, airports, flight times, cabin classes and more to their preference. Book your flight to Panama from Manchester today with Cheapflights!

Why should you use Cheapflights to find cheap flight tickets from Manchester to Panama?

Cheapflights helps you find that perfect flight to Panama from Manchester by searching from hundreds of airlines and agencies you know and love. We are also free to use, in case you were wondering!

Can Cheapflights find flights from Manchester to Panama with no change fees?

Cheapflights does show flights with no change fees to all users. To see these options for flights from Manchester to Panama, users can toggle the no change fees filter when performing a flight search.

Can Cheapflights notify me if prices for flights from Manchester to Panama become cheaper?

Yes, Cheapflights offers price alerts on Manchester to Panama flights so you can book your travel at the perfect time. Price Alerts can be enabled by clicking the bell icon next to the flight deals above and providing your email address where you want to receive the alerts.

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.