Cheap flights from Manchester to Panama from £605

This is the cheapest retur flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/1. Fares are subject to change and may not be available on all flights or dates of travel.
MAN — PTY
31 Aug — 7 Sep1
1 adult

Cheap flight deals from Manchester to Panama

Keep the following information in mind while searching for Manchester to Panama flight deals. Data was last updated 26 August 2025.

Round-trip from

£605

Popular in

December

Cheapest in

September

Average price

£694
Lufthansa
  • Lufthansa
  • 6/1-16/1
  • 4 total stops
  • 62h 45m total
  • Manchester to Panama
Highest demand for flights based on searches. 12% potential increase in price (£81 potential increase over avg. return price).
Cheapest flight prices on average. 5% potential price decrease (£31 potential savings vs. average return price).
Average for round-trip flights in August 2025

Find flight deals from Manchester to Panama

Cheapest flights from Manchester to Panama
Explore the most affordable flight options available from Manchester to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 26 August 2025.

Thu 20/1109:25MAN - PTY
2 stops33h 30mLufthansa
Sat 29/1110:00PTY - MAN
2 stops26h 00mLufthansa
Deal found 25/8£628
Fri 26/906:05MAN - PTY
2 stops44h 05mUnited Airlines
Fri 10/1015:35PTY - MAN
2 stops43h 45mUnited Airlines
Deal found 24/8£655
Thu 20/1117:05MAN - PTY
1 stop32h 05mAir France
Sat 29/1115:37PTY - MAN
1 stop33h 53mAir France
Deal found 25/8£667
Thu 20/1120:10MAN - PTY
2 stops28h 35mMultiple Airlines
Sat 29/1121:30PTY - MAN
3 stops33h 20mMultiple Airlines
Deal found 25/8£675
Thu 23/1006:05MAN - PTY
2 stops38h 09mUnited Airlines
Thu 30/1015:41PTY - MAN
2 stops44h 19mUnited Airlines
Deal found 25/8£680
Fri 26/917:45MAN - PTY
1 stop30h 00mMultiple Airlines
Fri 10/1018:50PTY - MAN
1 stop20h 55mMultiple Airlines
Deal found 24/8£702
Fri 14/1105:50MAN - PTY
2 stops19h 09mDelta
Sun 23/1108:05PTY - MAN
1 stop17h 25mDelta
Deal found 25/8£724
Fri 26/917:45MAN - PTY
1 stop30h 00mAir France
Fri 10/1018:50PTY - MAN
2 stops16h 25mAir France
Deal found 24/8£727
Fri 14/1106:00MAN - PTY
2 stops29h 13mUnited Airlines
Sun 23/1109:11PTY - MAN
2 stops26h 49mUnited Airlines
Deal found 25/8£731
Thu 23/1005:55MAN - PTY
2 stops17h 50mKLM
Thu 30/1018:45PTY - MAN
1 stop32h 35mKLM
Deal found 25/8£786

Cheapflights Fare Finder

 
Customise your flight search to find flights from Manchester to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 26 August 2025.
Use the filters below to find and compare flights from Manchester to Panama that are best for you.

Fly from

Manchester

Fly to

Panama

Route

Depart

Return

Price

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Tue 6/1

06:10-13:55

2 stops36h 45m

Panama City Tocumen Intl

Fri 16/1

10:00-17:00

2 stops26h 00m

£605

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Thu 20/11

09:25-13:55

2 stops33h 30m

Panama City Tocumen Intl

Sat 29/11

10:00-17:00

2 stops26h 00m

£628

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Mon 5/1

06:10-13:55

2 stops36h 45m

Panama City Tocumen Intl

Thu 15/1

10:00-10:20

2 stops19h 20m

£630

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Tue 6/1

13:00-17:07

3 stops57h 07m

Panama City Tocumen Intl

Fri 16/1

10:00-10:20

2 stops19h 20m

£639

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Fri 26/9

06:05-20:10

2 stops44h 05m

Panama City Tocumen Intl

Fri 10/10

15:35-17:20

2 stops43h 45m

£655

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Thu 20/11

17:05-20:10

1 stop32h 05m

Panama City Tocumen Intl

Sat 29/11

15:37-06:30

1 stop33h 53m

£667

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Mon 5/1

06:00-17:07

3 stops40h 07m

Panama City Tocumen Intl

Thu 15/1

10:00-10:20

2 stops19h 20m

£674

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Thu 20/11

20:10-19:45

2 stops28h 35m

Panama City Tocumen Intl

Sat 29/11

21:30-11:50

3 stops33h 20m

£675

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Thu 23/10

06:05-14:14

2 stops38h 09m

Panama City Tocumen Intl

Thu 30/10

15:41-17:00

2 stops44h 19m

£680

Flights are sorted by cheapest return flights first.

Deals found on 24/8

Best time to book a flight from Manchester to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Manchester with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to Panama

What is the cheapest month to book a flight from Manchester to Panama?

Currently, April is the cheapest month in which you can book a flight from Manchester to Panama (average of £763). Flying from Manchester to Panama in December is currently the most expensive (average of £1,051). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MAN to PA?

Find hourly flight availability from Manchester to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 26 August 2025.

When flying from Manchester to Panama, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated 26 August 2025.
Get a feel of what it's like to fly with KLM, Air France, andUnited Airlines from Manchester to Panama by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Food

7.3

Crew

8.4

Entertainment

7.1

Overall

7.8

Boarding

7.8

Comfort

7.7

Reviews

1 / 20
4.0
Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.

Food

7.3

Crew

8.4

Entertainment

7.1

Overall

7.8

Boarding

7.8

Comfort

7.7

Reviews

1 / 20
4.0
Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.

Food

7.3

Crew

8.4

Entertainment

7.1

Overall

7.8

Boarding

7.8

Comfort

7.7

Reviews

1 / 20
4.0
Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.

Food

7.3

Crew

8.4

Entertainment

7.1

Overall

7.8

Boarding

7.8

Comfort

7.7

Reviews

1 / 20
4.0
Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.

Food

7.3

Crew

8.4

Entertainment

7.1

Overall

7.8

Boarding

7.8

Comfort

7.7

Reviews

1 / 20
4.0
Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.

Food

7.3

Crew

8.4

Entertainment

7.1

Overall

7.8

Boarding

7.8

Comfort

7.7

Reviews

1 / 20
4.0
Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.

Related info for your journey

Find useful and relevant information for your journey from Manchester to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Manchester to Panama?

    Manchester (MAN) is the airport you will fly out of if you book a flight from Manchester to Panama. It is only a 8.9 mi journey to Manchester (MAN) from Manchester’s city center.

  • How long is the flight from Manchester to Panama?

    Lufthansa can get you from Manchester to Panama in just under 36h 45m. Your travel time can differ by up to . Airlines will cover a distance of 5182 mi.

  • Can I find deals for flights from Manchester to Panama that include hotel bookings?

    Yes. In addition to deals on Manchester to Panama flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Manchester to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to Panama.

  • Can I find deals for business class flights from Manchester to Panama?

    Yes. Cheapflights offers flight deals from Manchester to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester to Panama?

    Currently, April is the cheapest month in which you can book a flight from Manchester to Panama (average of £763). Flying from Manchester to Panama in December is currently the most expensive (average of £1,051). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Manchester to Panama

See prices for flight routes from nearby airports that may be better suited for you.

Top 5 airlines flying from Manchester to Panama

Discover the top 5 airlines that operate flights from Manchester to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 26 August 2025.
AirlineCheapestAverageFlexibilityOn-time
Air FranceCheapest£559Average£703FlexibilityNo cancel feeOn-time77%
Search Air France flights
KLMCheapest£576Average£780FlexibilityNo cancel feeOn-time75%
Search KLM flights
United AirlinesCheapest£582Average£696FlexibilityNo cancel feeOn-time69%
Search United Airlines flights
Turkish AirlinesCheapest£622Average£993FlexibilityNo cancel feeOn-time77%
Search Turkish Airlines flights
LufthansaCheapest£625Average£671FlexibilityNo cancel feeOn-time76%
Search Lufthansa flights

Fly with Cheapflights

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How does Cheapflights help users find flights from Manchester to Panama?

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Can Cheapflights find flights from Manchester to Panama with no change fees?

Cheapflights does show flights with no change fees to all users. To see these options for flights from Manchester to Panama, users can toggle the no change fees filter when performing a flight search.

Can Cheapflights notify me if prices for flights from Manchester to Panama become cheaper?

Yes, Cheapflights offers price alerts on Manchester to Panama flights so you can book your travel at the perfect time. Price Alerts can be enabled by clicking the bell icon next to the flight deals above and providing your email address where you want to receive the alerts.

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