Cheap flights from Manchester to Panama from £306

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 15/3. Fares are subject to change and may not be available on all flights or dates of travel.
MAN — PTY
22 Mar — 29 Mar1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Manchester to Panama

Enter your travel dates to find the best prices.

Cheapest flights from Manchester to Panama
Explore the most affordable flight options available from Manchester to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 20 February 2026.

Wed 15/409:30
MAN
-
PTY
1 stop15h 10m
Multiple Airlines
Sat 25/421:33
PTY
-
MAN
2 stops32h 07m
Multiple Airlines
Deal found 18/2£654
Wed 15/406:05
MAN
-
PTY
2 stops38h 09m
United Airlines
Sat 25/415:30
PTY
-
MAN
2 stops36h 55m
United Airlines
Deal found 18/2£658
Mon 16/306:15
MAN
-
PTY
1 stop18h 30m
Multiple Airlines
Mon 23/321:30
PTY
-
MAN
1 stop15h 10m
Multiple Airlines
Deal found 16/2£659
Sat 4/406:05
MAN
-
PTY
2 stops38h 09m
United Airlines
Sat 18/415:30
PTY
-
MAN
2 stops36h 55m
United Airlines
Deal found 17/2£662
Thu 7/505:55
MAN
-
PTY
2 stops40h 17m
United Airlines
Mon 11/509:45
PTY
-
MAN
2 stops25h 25m
United Airlines
Deal found 19/2£663
Mon 16/322:25
MAN
-
PTY
2 stops23h 40m
Turkish Airlines
Mon 23/321:45
PTY
-
MAN
1 stop31h 05m
Turkish Airlines
Deal found 16/2£673
Sun 1/313:00
MAN
-
PTY
2 stops35h 45m
Multiple Airlines
Thu 12/321:30
PTY
-
MAN
3 stops33h 20m
Multiple Airlines
Deal found 16/2£687

Find flight deals from Manchester to Panama

Keep the following information in mind while searching for Manchester to Panama flight deals. Data was last updated 20 February 2026.

Round-trip from

£654

One-way from

£306

Popular in

December

Cheapest in

September

Average price

£781
15/4-25/4
  • 15/4-25/4
  • 3 total stops
  • 47h 17m total
  • Manchester to Panama
15/3
  • 15/3
  • 1 total stop
  • 18h 35m total
  • Manchester to Panama
Highest demand for flights based on searches. 5% potential increase in price (£31 potential increase over avg. return price).
Cheapest flight prices on average. 1% potential price decrease (£9 potential savings vs. average return price).
Average for round-trip flights in February 2026

Cheapflights Fare Finder

 
Customise your flight search to find flights from Manchester to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 20 February 2026.
Use the filters below to find and compare flights from Manchester to Panama that are best for you.

Fly from

Manchester

Fly to

Panama

Route

Depart

Return

Price

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Wed 15/4

09:30-18:40

1 stop15h 10m

Panama City Tocumen Intl

Sat 25/4

21:33-11:40

2 stops32h 07m

£654

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Wed 15/4

06:05-14:14

2 stops38h 09m

Panama City Tocumen Intl

Sat 25/4

15:30-10:25

2 stops36h 55m

£658

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Sat 4/4

06:05-14:14

2 stops38h 09m

Panama City Tocumen Intl

Sat 18/4

15:30-10:25

2 stops36h 55m

£662

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Thu 7/5

05:55-16:12

2 stops40h 17m

Panama City Tocumen Intl

Mon 11/5

09:45-17:10

2 stops25h 25m

£663

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Thu 28/5

05:55-14:14

2 stops38h 19m

Panama City Tocumen Intl

Tue 2/6

15:30-06:30

2 stops57h 00m

£667

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Mon 16/3

22:25-17:05

2 stops23h 40m

Panama City Tocumen Intl

Mon 23/3

21:45-09:50

1 stop31h 05m

£673

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Sun 1/3

13:00-19:45

2 stops35h 45m

Panama City Tocumen Intl

Thu 12/3

21:30-11:50

3 stops33h 20m

£687

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Sun 15/3

06:10-19:45

1 stop18h 35m

£306

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Wed 22/4

14:55-19:45

1 stop34h 50m

£657

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Wed 22/4

20:50-19:45

2 stops28h 55m

£692

Flights are sorted by cheapest return flights first.

Deals found on 18/2

Showing 1-10 of 14 results
1
2

Best time to book a flight from Manchester to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Manchester with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to Panama

What is the cheapest month to book a flight from Manchester to Panama?

Currently, November is the cheapest month in which you can book a flight from Manchester to Panama (average of £559). Flying from Manchester to Panama in December is currently the most expensive (average of £692). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated 20 February 2026.
Get a feel of what it's like to fly with KLM, Air France, andUnited Airlines from Manchester to Panama by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Boarding

7.8

Comfort

7.6

Crew

8.4

Food

7.3

Overall

7.7

Entertainment

7.1

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas

Boarding

7.8

Comfort

7.6

Crew

8.4

Food

7.3

Overall

7.7

Entertainment

7.1

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas

Boarding

7.8

Comfort

7.6

Crew

8.4

Food

7.3

Overall

7.7

Entertainment

7.1

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas

Boarding

7.8

Comfort

7.6

Crew

8.4

Food

7.3

Overall

7.7

Entertainment

7.1

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas

Boarding

7.8

Comfort

7.6

Crew

8.4

Food

7.3

Overall

7.7

Entertainment

7.1

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas

Boarding

7.8

Comfort

7.6

Crew

8.4

Food

7.3

Overall

7.7

Entertainment

7.1

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas

Related info for your journey

Find useful and relevant information for your journey from Manchester to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Manchester to Panama?

    Manchester (MAN) is the airport you will fly out of if you book a flight from Manchester to Panama. It is only a 8.9 mi journey to Manchester (MAN) from Manchester’s city center.

  • How long is the flight from Manchester to Panama?

    United Airlines can get you from Manchester to Panama in just under 38h 09m. Your travel time can differ by up to . Airlines will cover a distance of 5182 mi.

  • Can I find deals for flights from Manchester to Panama that include hotel bookings?

    Yes. In addition to deals on Manchester to Panama flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Manchester to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to Panama.

  • Can I find deals for business class flights from Manchester to Panama?

    Yes. Cheapflights offers flight deals from Manchester to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester to Panama?

    Currently, November is the cheapest month in which you can book a flight from Manchester to Panama (average of £559). Flying from Manchester to Panama in December is currently the most expensive (average of £692). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Manchester to Panama

See prices for flight routes from nearby airports that may be better suited for you.

Top 5 airlines flying from Manchester to Panama

Discover the top 5 airlines that operate flights from Manchester to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 20 February 2026.
AirlineCheapestAverageFlexibilityOn-time
Air FranceCheapest£560Average£704FlexibilityNo cancel feeOn-time77%
Search Air France flights
KLMCheapest£587Average£822FlexibilityNo cancel feeOn-time75%
Search KLM flights
United AirlinesCheapest£603Average£691FlexibilityNo cancel feeOn-time69%
Search United Airlines flights
LufthansaCheapest£626Average£672FlexibilityNo cancel feeOn-time76%
Search Lufthansa flights
Turkish AirlinesCheapest£653Average£716FlexibilityNo cancel feeOn-time77%
Search Turkish Airlines flights

Fly with Cheapflights

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How does Cheapflights help users find flights from Manchester to Panama?

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Why should you use Cheapflights to find cheap flight tickets from Manchester to Panama?

Cheapflights helps you find that perfect flight to Panama from Manchester by searching from hundreds of airlines and agencies you know and love. We are also free to use, in case you were wondering!

Can Cheapflights find flights from Manchester to Panama with no change fees?

Cheapflights does show flights with no change fees to all users. To see these options for flights from Manchester to Panama, users can toggle the no change fees filter when performing a flight search.

Can Cheapflights notify me if prices for flights from Manchester to Panama become cheaper?

Yes, Cheapflights offers price alerts on Manchester to Panama flights so you can book your travel at the perfect time. Price Alerts can be enabled by clicking the bell icon next to the flight deals above and providing your email address where you want to receive the alerts.

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