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Cheap flights from Madrid, Spain to Santa Cruz de la Sierra from £302

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/9. Fares are subject to change and may not be available on all flights or dates of travel.
MAD — VVI
18 Jun — 25 Jun1
1 adult

Cheapflights Tip: The best prices from Madrid Barajas to Santa Cruz de la Sierra Viru Viru Intl are usually found in May or March, booked 68 days in advance, depart on a Thursday or Tuesday and return on a Monday

Cheap flight deals from Madrid to Santa Cruz de la Sierra

Discover tips and strategies to find the most affordable flight options for your journey from Madrid (MAD) to Santa Cruz de la Sierra (VVI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 13 June 2025.

Round-trip from

£727

One-way from

£302

Popular in

August

Cheapest in

May

Average price

£821
Avianca
  • Avianca
  • 27/6-9/7
  • 2 total stops
  • 36h 45m total
  • Madrid to Santa Cruz de la Sierra
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Avianca
  • Avianca
  • 3/9
  • 1 total stop
  • 22h 10m total
  • Madrid to Santa Cruz de la Sierra
Search Deals
Highest demand for flights based on searches. 14% potential increase in price (£92 potential increase over avg. return price).
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Cheapest flight prices on average. 3% potential price decrease (£20 potential savings vs. average return price).
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Average for round-trip flights in June 2025
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Find flight deals from Madrid to Santa Cruz de la Sierra

Cheapest flights from Madrid to Santa Cruz de la Sierra
Explore the most affordable flight options available from Madrid to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 13 June 2025.

Fri 27/609:40MAD - VVI
1 stop22h 10mAvianca
Wed 9/702:55VVI - MAD
1 stop14h 35mAvianca
Deal found 11/6£727
Fri 10/1006:00MAD - VVI
2 stops25h 50mMultiple Airlines
Sat 25/1003:05VVI - MAD
3 stops34h 40mMultiple Airlines
Deal found 11/6£835
Thu 4/911:15MAD - VVI
2 stops41h 10mUnited Airlines
Sat 20/901:09VVI - MAD
2 stops25h 51mUnited Airlines
Deal found 11/6£869

Cheapflights Fare Finder

Customise your flight search to find flights from Madrid to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 13 June 2025.
Use the filters below to find and compare flights from Madrid to Santa Cruz de la Sierra that are best for you.

Fly from

Madrid

Fly to

Santa Cruz de la Sierra

Route

Depart

Return

Price

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Fri 27/6

09:40-01:50

1 stop22h 10m

Santa Cruz de la Sierra Viru Viru Intl

Wed 9/7

02:55-23:30

1 stop14h 35m

£727

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Fri 10/10

06:00-01:50

2 stops25h 50m

Santa Cruz de la Sierra Viru Viru Intl

Sat 25/10

03:05-18:45

3 stops34h 40m

£835

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Thu 4/9

11:15-22:25

2 stops41h 10m

Santa Cruz de la Sierra Viru Viru Intl

Sat 20/9

01:09-09:00

2 stops25h 51m

£869

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Wed 3/9

09:40-01:50

1 stop22h 10m

£302

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Wed 3/9

11:15-22:25

2 stops41h 10m

£495

Flights are sorted by cheapest return flights first.

Deals found on 11/6

Best time to book a flight from Madrid to Santa Cruz de la Sierra

Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from Madrid with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Madrid to Santa Cruz de la Sierra

How far ahead should I book a flight from Madrid to Santa Cruz de la Sierra?

Use this chart to determine the optimal time to book a return flight from Madrid to Santa Cruz de la Sierra. Price data was last updated on 9 June 2025.

The price you pay for your flight from Madrid to Santa Cruz de la Sierra may vary depending on when you book. For the best chance of a lower fare, look to book 68 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest time of day to fly from MAD to VVI?

Find hourly flight availability from Madrid to Santa Cruz de la Sierra. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 13 June 2025.

It’s typically best to fly out from Madrid to Santa Cruz de la Sierra in the afternoon. Doing so could potentially save you 32% on the flight price compared to flying in the morning, which is usually more expensive.

Reviews of airlines servicing Santa Cruz de la Sierra

Get insights into the airlines that provide service to Santa Cruz de la Sierra. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Cruz de la Sierra. Reviews last updated 13 June 2025.
United Airlines
7.4
Good
8,790 reviews
Check prices

Boarding

7.7

Comfort

7.3

Food

6.6

Overall

7.4

Entertainment

7.0

Crew

8.1

Reviews

1 / 20
4.0
Okay

Thomas,Mar 2025

SFO - TPE

When I asked for an extra snack, I got an unhappy look from the stewardess. Geez, does one extra snack really affect the bottom line??
United Airlines
7.4
Good
8,790 reviews
United Airlines
7.4
Good
8,790 reviews
Check prices

Boarding

7.7

Comfort

7.3

Food

6.6

Overall

7.4

Entertainment

7.0

Crew

8.1

Reviews

1 / 20
4.0
Okay

Thomas,Mar 2025

SFO - TPE

When I asked for an extra snack, I got an unhappy look from the stewardess. Geez, does one extra snack really affect the bottom line??
Avianca
6.7
Okay
2,345 reviews
United Airlines
7.4
Good
8,790 reviews
Check prices

Boarding

7.7

Comfort

7.3

Food

6.6

Overall

7.4

Entertainment

7.0

Crew

8.1

Reviews

1 / 20
4.0
Okay

Thomas,Mar 2025

SFO - TPE

When I asked for an extra snack, I got an unhappy look from the stewardess. Geez, does one extra snack really affect the bottom line??

Related info for your journey

Find useful and relevant information for your journey from Madrid to Santa Cruz de la Sierra. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Madrid to Santa Cruz de la Sierra flight route?

    The Madrid Barajas to Santa Cruz de la Sierra Viru Viru Intl flight path was viewed by 12 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines flying from Madrid to Santa Cruz de la Sierra round-trip?

    Avianca, at £727, was found to be the cheapest airline from Madrid to Santa Cruz de la Sierra. An alternate airline flying to your destination would be United Airlines. Users have found that Avianca is 4% cheaper than the other options available to this destination.

  • What are the cheapest flights from Madrid to Santa Cruz de la Sierra?

    Looking for the cheapest flight from Madrid to Santa Cruz de la Sierra? While on average our users pay £1,149, our data indicates the cheapest price to be £368. The most popular route (Madrid Barajas - Santa Cruz de la Sierra Viru Viru Intl), is priced around £957.

  • Can I find deals for flights from Madrid to Santa Cruz de la Sierra that include hotel bookings?

    Yes. In addition to deals on Madrid to Santa Cruz de la Sierra flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Madrid to Santa Cruz de la Sierra?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Madrid to Santa Cruz de la Sierra.

  • Can I find deals for business class flights from Madrid to Santa Cruz de la Sierra?

    Yes. Cheapflights offers flight deals from Madrid to Santa Cruz de la Sierra by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Madrid to Santa Cruz de la Sierra

See prices for flight routes from nearby airports that may be better suited for you.
Madrid to La Paz flights

Top 3 airlines flying from Madrid to Santa Cruz de la Sierra

Discover the top 3 airlines that operate flights from Madrid to Santa Cruz de la Sierra. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 13 June 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest£530Average£635FlexibilityNo cancel feeOn-time71%
Search Avianca flights
BoACheapest£546Average£895FlexibilityNo cancel feeOn-timeN/A
Search BoA flights
IberiaCheapest£547Average£592FlexibilityNo cancel feeOn-time77%
Search Iberia flights

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How does Cheapflights help users find flights from Madrid to Santa Cruz de la Sierra?

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Why should you use Cheapflights to find cheap flight tickets from Madrid to Santa Cruz de la Sierra?

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Can Cheapflights find flights from Madrid to Santa Cruz de la Sierra with no change fees?

Need flexible booking options for your flight to Santa Cruz de la Sierra from Madrid? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

Can Cheapflights notify me if prices for flights from Madrid to Santa Cruz de la Sierra become cheaper?

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