Cheap flights from Madrid, Spain to Santiago from £350
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 27/8. Fares are subject to change and may not be available on all flights or dates of travel.
MAD — SCL
11 Jul — 18 Jul1
Return
1 adult
Economy
Return
1 adult, Economy, 0 bags
Cheapflights Tip: The best prices from Madrid Barajas to Santiago Arturo Merino Benitez are usually found in May or March, booked 45 days in advance, depart on a Monday or Sunday and return on a Tuesday
Cheap flight deals from Madrid to Santiago
Enter your travel dates to find the best prices.
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Cheapest flights from Madrid to Santiago
Explore the most affordable flight options available from Madrid to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 11 June 2026.
Sun 1/1113:00
MAD
-
SCL
Nonstop13h 20m
Iberia
Sat 28/1100:50
SCL
-
MAD
Nonstop12h 40m
Iberia
Deal found 6/6£647
Thu 29/1011:55
MAD
-
SCL
1 stop23h 45m
Delta
Fri 13/1123:10
SCL
-
MAD
1 stop30h 45m
Delta
Deal found 7/6£648
Tue 1/923:59
MAD
-
SCL
Nonstop13h 26m
Iberia
Tue 29/910:05
SCL
-
MAD
Nonstop14h 40m
Iberia
Deal found 7/6£649
Wed 9/906:00
MAD
-
SCL
2 stops31h 15m
Delta
Mon 21/920:40
SCL
-
MAD
2 stops41h 55m
Delta
Deal found 8/6£652
Tue 1/910:05
MAD
-
SCL
2 stops27h 10m
Delta
Tue 15/920:40
SCL
-
MAD
2 stops41h 55m
Delta
Deal found 10/6£654
Thu 5/1113:00
MAD
-
SCL
Nonstop13h 20m
Iberia
Thu 19/1113:45
SCL
-
MAD
1 stop20h 10m
Iberia
Deal found 8/6£654
Mon 2/1113:00
MAD
-
SCL
Nonstop13h 20m
Iberia
Thu 19/1113:45
SCL
-
MAD
1 stop18h 15m
Iberia
Deal found 9/6£655
Sun 11/1007:05
MAD
-
SCL
2 stops30h 10m
Delta
Thu 5/1123:10
SCL
-
MAD
2 stops34h 30m
Delta
Deal found 9/6£658
Mon 5/1006:00
MAD
-
SCL
2 stops31h 15m
Delta
Thu 5/1123:10
SCL
-
MAD
2 stops34h 30m
Delta
Deal found 9/6£659
Mon 26/1013:05
MAD
-
SCL
2 stops46h 35m
Delta
Mon 23/1123:10
SCL
-
MAD
2 stops30h 50m
Delta
Deal found 11/6£660
Tue 3/1113:00
MAD
-
SCL
Nonstop13h 20m
Iberia
Mon 30/1111:50
SCL
-
MAD
1 stop22h 05m
Iberia
Deal found 7/6£660
Best flights from Madrid to Santiago
Discover carefully curated flight deals from Madrid to Santiago that have cost, travel time, and stopovers in mind to ensure you get the best travel experience. Data last updated 11 June 2026.
Thu 24/912:45
MAD
-
SCL
2 stops48h 30m
Delta
Sun 4/1020:40
SCL
-
MAD
2 stops36h 00m
Delta
Deal found 8/6£677
Thu 3/1214:20
MAD
-
SCL
3 stops43h 32m
Turkish Airlines
Wed 17/211:45
SCL
-
MAD
2 stops45h 30m
Turkish Airlines
Deal found 11/6£822
Wed 1/717:20
MAD
-
SCL
2 stops21h 25m
Multiple Airlines
Tue 7/710:00
SCL
-
MAD
1 stop23h 35m
Multiple Airlines
Deal found 8/6£1,009
Wed 23/912:45
MAD
-
SCL
2 stops48h 30m
Delta
Tue 29/920:40
SCL
-
MAD
2 stops41h 55m
Delta
Deal found 8/6£725
Sat 24/1007:40
MAD
-
SCL
2 stops55h 20m
Turkish Airlines
Mon 2/1111:45
SCL
-
MAD
2 stops45h 30m
Turkish Airlines
Deal found 7/6£870
Mon 5/1006:00
MAD
-
SCL
2 stops31h 15m
Delta
Sat 17/1020:40
SCL
-
MAD
1 stop34h 35m
Delta
Deal found 6/6£797
Thu 24/912:45
MAD
-
SCL
2 stops48h 30m
Delta
Tue 29/920:40
SCL
-
MAD
2 stops41h 55m
Delta
Deal found 8/6£820
Thu 3/1211:55
MAD
-
SCL
3 stops45h 57m
Turkish Airlines
Mon 28/1211:45
SCL
-
MAD
2 stops45h 30m
Turkish Airlines
Deal found 8/6£938
Wed 19/809:50
MAD
-
SCL
1 stop27h 25m
Delta
Sat 29/820:40
SCL
-
MAD
2 stops27h 40m
Delta
Deal found 7/6£863
Tue 15/912:00
MAD
-
SCL
2 stops50h 30m
Turkish Airlines
Mon 2/1111:45
SCL
-
MAD
2 stops45h 30m
Turkish Airlines
Deal found 9/6£969
Sun 18/1012:00
MAD
-
SCL
2 stops50h 30m
Turkish Airlines
Sat 31/1011:45
SCL
-
MAD
2 stops45h 30m
Turkish Airlines
Deal found 7/6£992
Sun 9/809:50
MAD
-
SCL
1 stop27h 25m
Delta
Tue 25/820:40
SCL
-
MAD
2 stops27h 40m
Delta
Deal found 10/6£908
Direct flights from Madrid to Santiago
Explore direct flight options from Madrid to Santiago based on user searches, and compare prices and availability for your desired travel dates. Data last updated 11 June 2026.
Sun 1/1113:00
MAD
-
SCL
Nonstop13h 20m
Iberia
Sat 28/1100:50
SCL
-
MAD
Nonstop12h 40m
Iberia
Deal found 6/6£647
Tue 1/923:59
MAD
-
SCL
Nonstop13h 26m
Iberia
Tue 29/910:05
SCL
-
MAD
Nonstop14h 40m
Iberia
Deal found 7/6£649
Sun 1/1113:00
MAD
-
SCL
Nonstop13h 20m
Iberia
Fri 13/1100:50
SCL
-
MAD
Nonstop12h 40m
Iberia
Deal found 9/6£670
Fri 6/1113:00
MAD
-
SCL
Nonstop13h 20m
Iberia
Thu 19/1100:50
SCL
-
MAD
Nonstop12h 40m
Iberia
Deal found 10/6£671
Sat 12/923:59
MAD
-
SCL
Nonstop13h 26m
Iberia
Sun 27/923:00
SCL
-
MAD
Nonstop12h 40m
Iberia
Deal found 10/6£701
Thu 3/1213:00
MAD
-
SCL
Nonstop13h 20m
Iberia
Mon 21/1212:50
SCL
-
MAD
Nonstop12h 35m
Iberia
Deal found 8/6£788
Fri 27/1113:00
MAD
-
SCL
Nonstop13h 20m
Iberia
Mon 28/1212:50
SCL
-
MAD
Nonstop12h 35m
Iberia
Deal found 10/6£789
Thu 3/1213:00
MAD
-
SCL
Nonstop13h 20m
Iberia
Wed 17/212:50
SCL
-
MAD
Nonstop12h 35m
Iberia
Deal found 11/6£790
Sun 1/1113:00
MAD
-
SCL
Nonstop13h 20m
Iberia
Sat 26/1200:50
SCL
-
MAD
Nonstop12h 40m
Iberia
Deal found 9/6£814
Sat 31/1013:00
MAD
-
SCL
Nonstop13h 20m
Iberia
Sat 28/1112:50
SCL
-
MAD
Nonstop12h 35m
Iberia
Deal found 9/6£853
Last-minute flights from Madrid to Santiago
Discover last-minute flight deals from Madrid to Santiago. Data last updated 11 June 2026 and is based on user searches.
Thu 11/612:45
MAD
-
SCL
2 stops24h 30m
Delta
Wed 2/920:40
SCL
-
MAD
2 stops27h 40m
Delta
Deal found 9/6£864
Thu 11/617:20
MAD
-
SCL
2 stops21h 25m
KLM
Thu 18/610:15
SCL
-
MAD
2 stops31h 10m
KLM
Deal found 10/6£889
Thu 11/617:20
MAD
-
SCL
2 stops21h 25m
KLM
Sun 21/610:15
SCL
-
MAD
2 stops24h 10m
KLM
Deal found 8/6£890
Thu 11/613:05
MAD
-
SCL
2 stops25h 40m
Multiple Airlines
Sun 21/610:00
SCL
-
MAD
1 stop19h 20m
Multiple Airlines
Deal found 8/6£891
Thu 11/610:25
MAD
-
SCL
2 stops28h 20m
Multiple Airlines
Mon 15/610:00
SCL
-
MAD
1 stop27h 15m
Multiple Airlines
Deal found 11/6£892
Fri 12/623:59
MAD
-
SCL
Nonstop13h 26m
Iberia
Fri 19/610:40
SCL
-
MAD
Nonstop12h 40m
Iberia
Deal found 11/6£859
Fri 12/611:00
MAD
-
SCL
1 stop24h 30m
Multiple Airlines
Sat 13/608:31
SCL
-
MAD
1 stop22h 34m
Multiple Airlines
Deal found 10/6£884
Tue 16/610:25
MAD
-
SCL
2 stops28h 20m
KLM
Sun 21/610:15
SCL
-
MAD
2 stops24h 10m
KLM
Deal found 8/6£880
Thu 18/610:25
MAD
-
SCL
2 stops28h 20m
Multiple Airlines
Wed 22/710:00
SCL
-
MAD
1 stop19h 20m
Multiple Airlines
Deal found 9/6£888
Wed 15/706:00
MAD
-
SCL
2 stops31h 15m
Delta
Thu 20/820:40
SCL
-
MAD
2 stops31h 15m
Delta
Deal found 7/6£901
Wed 15/712:45
MAD
-
SCL
2 stops48h 30m
Delta
Sun 23/820:40
SCL
-
MAD
1 stop33h 35m
Delta
Deal found 8/6£907
Thu 16/712:45
MAD
-
SCL
2 stops48h 30m
Delta
Sun 23/820:40
SCL
-
MAD
1 stop33h 35m
Delta
Deal found 8/6£864
One-way flights from Madrid to Santiago
Search for one-way flight options from Madrid to Santiago. Find affordable one-way fares based on user searches. Data last updated 11 June 2026.
Thu 27/823:59
MAD
-
SCL
Nonstop13h 26m
Iberia
Deal found 7/6£350
Wed 16/902:20
MAD
-
SCL
1 stop17h 55m
Avianca
Deal found 9/6£412
Wed 26/802:10
MAD
-
SCL
2 stops27h 10m
Avianca
Deal found 7/6£414
Wed 28/1011:00
MAD
-
SCL
2 stops24h 50m
United Airlines
Deal found 9/6£421
Mon 2/1111:00
MAD
-
SCL
2 stops49h 50m
United Airlines
Deal found 8/6£422
Thu 12/1111:15
MAD
-
SCL
2 stops49h 35m
United Airlines
Deal found 10/6£423
Tue 3/1111:15
MAD
-
SCL
2 stops49h 35m
United Airlines
Deal found 11/6£426
Wed 4/1111:00
MAD
-
SCL
2 stops25h 50m
United Airlines
Deal found 11/6£427
Sun 1/1111:00
MAD
-
SCL
2 stops49h 50m
United Airlines
Deal found 10/6£427
Thu 19/1110:50
MAD
-
SCL
1 stop17h 40m
Avianca
Deal found 8/6£428
Wed 26/817:20
MAD
-
SCL
1 stop17h 25m
Avianca
Deal found 6/6£430
Find flight deals from Madrid to Santiago
Discover tips and strategies to find the most affordable flight options for your journey from Madrid (MAD) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 11 June 2026.
Customise your flight search to find flights from Madrid to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 11 June 2026.
Use the filters below to find and compare flights from Madrid to Santiago that are best for you.
Fly from
Fly to
Route
Depart
Return
Price
Cheapest return flight
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Thu 24/9
12:45-08:15
2 stops48h 30m
Santiago Arturo Merino Benitez
Sun 4/10
20:40-13:40
2 stops36h 00m
£677
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Wed 23/9
12:45-08:15
2 stops48h 30m
Santiago Arturo Merino Benitez
Tue 29/9
20:40-19:35
2 stops41h 55m
£725
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Mon 5/10
06:00-08:15
2 stops31h 15m
Santiago Arturo Merino Benitez
Sat 17/10
20:40-12:15
1 stop34h 35m
£797
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Thu 24/9
12:45-08:15
2 stops48h 30m
Santiago Arturo Merino Benitez
Tue 29/9
20:40-19:35
2 stops41h 55m
£820
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Thu 3/12
14:20-05:52
3 stops43h 32m
Santiago Arturo Merino Benitez
Wed 17/2
11:45-13:15
2 stops45h 30m
£822
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Wed 19/8
09:50-07:15
1 stop27h 25m
Santiago Arturo Merino Benitez
Sat 29/8
20:40-06:20
2 stops27h 40m
£863
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Sat 24/10
07:40-10:00
2 stops55h 20m
Santiago Arturo Merino Benitez
Mon 2/11
11:45-13:15
2 stops45h 30m
£870
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Sun 9/8
09:50-07:15
1 stop27h 25m
Santiago Arturo Merino Benitez
Tue 25/8
20:40-06:20
2 stops27h 40m
£908
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Thu 3/12
11:55-05:52
3 stops45h 57m
Santiago Arturo Merino Benitez
Mon 28/12
11:45-13:15
2 stops45h 30m
£938
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Tue 15/9
12:00-09:30
2 stops50h 30m
Santiago Arturo Merino Benitez
Mon 2/11
11:45-13:15
2 stops45h 30m
£969
Flights are sorted by cheapest return flights first.
Deals found on 10/6
Showing 1-10 of 24 resultsSorted by cheapest first
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3
Best time to book a flight from Madrid to Santiago
Have a flexible travel schedule? Discover the best time to fly to Santiago from Madrid with our price prediction graph.
MAD-SCL
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Madrid to Santiago
Prices
Airlines
Delays
How far ahead should I book a flight from Madrid to Santiago?
The price you pay for your flight from Madrid to Santiago may vary depending on when you book. For the best chance of a lower fare, look to book 44 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Madrid to Santiago?
Currently, May is the cheapest month in which you can book a flight from Madrid to Santiago (average of £681). Flying from Madrid to Santiago in July is currently the most expensive (average of £1,077). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MAD to SCL?
Find hourly flight availability from Madrid to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 11 June 2026.
When flying from Madrid to Santiago, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
How much does it cost for a return flight from Madrid to Santiago?
Weekly flight availability from Madrid to Santiago
Explore weekly flight availability from Madrid to Santiago. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated 11 June 2026.
The most flights from MAD to SCL are scheduled on a Wednesday (18 on average). You will have fewer flight options on Sunday, which is when the least amount of flights are scheduled (10 on average).
How often are flights from Madrid to Santiago delayed?
About 17% of weekly flights between Madrid and Santiago have experienced delays in the past year, with the average delay time being 120 minutes.
What is the most punctual flight time for Madrid to Santiago flights?
Historically, flights departing at night are less likely to be delayed, whereas flights leaving in the early afternoon tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Saturday tends to have the lowest number of delays on this route, whereas Friday has historically faced a higher average of delays compared to other days of the week.
Which airline has the best punctuality record on Madrid to Santiago flights?
Over the past year, LATAM Airlines have had the lowest number of delays on this route, with just 14% of flights being delayed.
Reviews of airlines servicing Santiago
Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated 11 June 2026.
Read through reviews of airlines operating flights from Madrid to Santiago, such as LATAM Airlines and Iberia. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Very old aircraft and it was very dirty in the seats and floor
Related info for your journey
Find useful and relevant information for your journey from Madrid to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
What airports do I use to fly from Madrid to Santiago?
To fly from Madrid to Santiago, you need to book a flight from Barajas (MAD) to Arturo Merino Benitez (SCL). Nonstop flights to Santiago Arturo Merino Benitez from Madrid Barajas take 12h 20m on average. When it comes time to book airfare, you have a few options: there are 13 outbound flights from Barajas to Arturo Merino Benitez offered by 2 different airlines.
How popular is this Madrid to Santiago flight route?
This flight path from Madrid Barajas to Santiago Arturo Merino Benitez was viewed by 18 users in the past month. Keep an eye out for changes in search interest prior to high and low season.
How long is the flight from Madrid to Santiago?
A quick flight from Madrid to Santiago can take about 43h 32m. Delta provides one of the quickest options available for as low as £822. Airlines will cover a distance of 6656 mi. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.
What are the cheapest airlines flying from Madrid to Santiago round-trip?
Cheapflights users have booked flights from Madrid to Santiago round-trip from £607. Another airline that can offer you cheap pricing is LATAM Airlines. Users have found that Iberia is 27% cheaper than the other options available to this destination.
What are the most reliable airlines from Madrid to Santiago?
No one likes to see their flight delayed. When booking a flight from Madrid to Santiago consider choosing Japan Airlines (82%), EL AL (82%) or Qatar Airways (68%) as they are the most reliable in getting you off to your destination on time.
What are the cheapest flights from Madrid to Santiago?
Looking at all options, your cheapest flight can be booked for £713. While the most popular route (Madrid Barajas - Santiago Arturo Merino Benitez) can be booked for £849 on average, our data indicates £714 when flying from Madrid to Santiago.
Can I find deals for business class flights from Madrid to Santiago?
Yes. Cheapflights offers flight deals from Madrid to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Madrid to Santiago?
Currently, May is the cheapest month in which you can book a flight from Madrid to Santiago (average of £681). Flying from Madrid to Santiago in July is currently the most expensive (average of £1,077). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Explore flights to Santiago departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on 11 June 2026.
Discover the top 2 airlines that operate flights from Madrid to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 11 June 2026.
Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.
How does Cheapflights help users find flights from Madrid to Santiago?
Cheapflights makes it easy to find Madrid to Santiago flights by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.
Why should you use Cheapflights to find cheap flight tickets from Madrid to Santiago?
Millions of users choose and trust Cheapflights to book the best flight deals from Madrid to Santiago for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.
Can Cheapflights find flights from Madrid to Santiago with no change fees?
Certainly. Search results for flights to Santiago from Madrid shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.
Can Cheapflights notify me if prices for flights from Madrid to Santiago become cheaper?
Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!
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