Cheap flights from Madrid, Spain to Santiago from £360
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/9. Fares are subject to change and may not be available on all flights or dates of travel.
MAD — SCL
4 Sep — 11 Sep1
Return
1 adult
Economy
Cheapflights Tip: The best prices from Madrid Barajas to Santiago Arturo Merino Benitez are usually found in March or April, booked 88 days in advance, depart on a Friday or Wednesday and return on a Monday
Cheap flight deals from Madrid to Santiago
Discover tips and strategies to find the most affordable flight options for your journey from Madrid (MAD) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 30 August 2025.
Explore the most affordable flight options available from Madrid to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 30 August 2025.
Sun 31/806:00MAD - SCL
2 stops31h 00mDelta
Tue 23/921:40SCL - MAD
2 stops37h 45mDelta
Deal found 28/8£651
Thu 18/910:05MAD - SCL
1 stop25h 55mDelta
Mon 29/921:40SCL - MAD
2 stops38h 05mDelta
Deal found 29/8£654
Fri 24/1006:00MAD - SCL
2 stops30h 00mDelta
Fri 28/1123:10SCL - MAD
1 stop30h 05mDelta
Deal found 28/8£654
Thu 13/1106:00MAD - SCL
2 stops30h 50mUnited Airlines
Thu 4/1222:45SCL - MAD
2 stops53h 20mUnited Airlines
Deal found 28/8£656
Tue 7/1007:30MAD - SCL
2 stops28h 30mDelta
Sat 25/1021:40SCL - MAD
1 stop30h 25mDelta
Deal found 29/8£657
Thu 23/1006:00MAD - SCL
2 stops30h 00mDelta
Thu 6/1123:10SCL - MAD
1 stop30h 05mDelta
Deal found 29/8£657
Mon 24/1111:15MAD - SCL
1 stop24h 25mDelta
Thu 27/1123:10SCL - MAD
1 stop28h 50mDelta
Deal found 30/8£658
Thu 4/912:40MAD - SCL
2 stops24h 20mDelta
Thu 2/1021:40SCL - MAD
2 stops40h 40mDelta
Deal found 27/8£660
Wed 19/1106:00MAD - SCL
2 stops29h 40mDelta
Tue 3/323:15SCL - MAD
2 stops36h 50mDelta
Deal found 29/8£661
Wed 8/1006:00MAD - SCL
2 stops30h 00mDelta
Wed 5/1123:10SCL - MAD
1 stop30h 05mDelta
Deal found 28/8£663
Thu 9/1006:00MAD - SCL
2 stops30h 00mDelta
Tue 14/1021:40SCL - MAD
2 stops53h 10mDelta
Deal found 28/8£663
Sun 7/915:10MAD - SCL
2 stops44h 50mDelta
Sun 15/223:15SCL - MAD
2 stops28h 45mDelta
Deal found 30/8£664
Best flights from Madrid to Santiago
Discover carefully curated flight deals from Madrid to Santiago that have cost, travel time, and stopovers in mind to ensure you get the best travel experience. Data last updated 30 August 2025.
Sun 28/1206:00MAD - SCL
2 stops28h 10mDelta
Wed 14/123:15SCL - MAD
2 stops32h 55mDelta
Deal found 29/8£654
Fri 24/1010:05MAD - SCL
1 stop25h 55mDelta
Wed 29/1022:10SCL - MAD
1 stop29h 55mDelta
Deal found 28/8£654
Sat 31/111:00MAD - SCL
1 stop24h 00mDelta
Thu 5/223:15SCL - MAD
1 stop29h 45mDelta
Deal found 28/8£654
Thu 18/906:00MAD - SCL
2 stops30h 00mDelta
Mon 29/921:40SCL - MAD
1 stop30h 55mDelta
Deal found 28/8£654
Fri 24/1006:00MAD - SCL
2 stops30h 00mDelta
Tue 18/1123:10SCL - MAD
2 stops31h 05mDelta
Deal found 30/8£654
Tue 3/211:00MAD - SCL
1 stop24h 00mDelta
Thu 5/223:15SCL - MAD
1 stop29h 45mDelta
Deal found 28/8£654
Mon 2/210:00MAD - SCL
2 stops49h 00mDelta
Thu 5/223:15SCL - MAD
1 stop29h 45mDelta
Deal found 28/8£654
Fri 24/1006:00MAD - SCL
2 stops30h 00mDelta
Fri 28/1123:10SCL - MAD
1 stop30h 05mDelta
Deal found 28/8£654
Sun 1/210:00MAD - SCL
2 stops49h 00mDelta
Thu 5/223:15SCL - MAD
1 stop29h 45mDelta
Deal found 28/8£654
Direct flights from Madrid to Santiago
Explore direct flight options from Madrid to Santiago based on user searches, and compare prices and availability for your desired travel dates. Data last updated 30 August 2025.
Tue 18/1112:55MAD - SCL
Nonstop13h 20mIberia
Wed 3/1213:05SCL - MAD
Nonstop12h 35mIberia
Deal found 28/8£793
Mon 17/1112:55MAD - SCL
Nonstop13h 20mIberia
Fri 26/1223:55SCL - MAD
Nonstop12h 40mIberia
Deal found 29/8£796
Fri 2/123:59MAD - SCL
Nonstop13h 21mIberia
Sat 24/113:05SCL - MAD
Nonstop12h 35mIberia
Deal found 30/8£797
Mon 29/1223:59MAD - SCL
Nonstop13h 21mIberia
Fri 16/123:55SCL - MAD
Nonstop12h 40mIberia
Deal found 28/8£880
Tue 7/1023:59MAD - SCL
Nonstop13h 25mIberia
Sun 26/1023:55SCL - MAD
Nonstop12h 40mIberia
Deal found 29/8£906
Sun 12/1013:20MAD - SCL
Nonstop13h 15mIberia
Sun 19/1011:55SCL - MAD
Nonstop12h 40mIberia
Deal found 28/8£937
Sat 6/1223:59MAD - SCL
Nonstop13h 21mIberia
Sat 13/1213:05SCL - MAD
Nonstop12h 35mIberia
Deal found 28/8£1,952
Tue 7/1013:20MAD - SCL
Nonstop13h 15mIberia
Sat 18/1011:55SCL - MAD
Nonstop12h 40mIberia
Deal found 30/8£2,745
Wed 10/923:59MAD - SCL
Nonstop13h 25mIberia
Tue 30/923:15SCL - MAD
Nonstop12h 40mIberia
Deal found 29/8£5,666
Last-minute flights from Madrid to Santiago
Discover last-minute flight deals from Madrid to Santiago. Data last updated 30 August 2025 and is based on user searches.
Sat 30/813:05MAD - SCL
2 stops47h 55mDelta
Wed 17/921:40SCL - MAD
1 stop30h 55mDelta
Deal found 28/8£671
Sun 31/806:00MAD - SCL
2 stops31h 00mDelta
Tue 23/921:40SCL - MAD
2 stops37h 45mDelta
Deal found 28/8£651
Sun 31/810:05MAD - SCL
1 stop26h 55mDelta
Fri 19/921:40SCL - MAD
1 stop30h 55mDelta
Deal found 28/8£680
Thu 4/912:40MAD - SCL
2 stops24h 20mDelta
Thu 2/1021:40SCL - MAD
2 stops40h 40mDelta
Deal found 27/8£660
Thu 4/912:40MAD - SCL
2 stops24h 20mDelta
Tue 23/921:40SCL - MAD
2 stops36h 55mDelta
Deal found 30/8£663
Thu 4/910:05MAD - SCL
1 stop26h 55mDelta
Mon 8/921:40SCL - MAD
2 stops36h 55mDelta
Deal found 30/8£672
Sun 7/915:10MAD - SCL
2 stops44h 50mDelta
Sat 14/223:15SCL - MAD
2 stops52h 45mDelta
Deal found 30/8£664
Mon 8/910:05MAD - SCL
1 stop25h 55mDelta
Sun 21/921:40SCL - MAD
2 stops38h 05mDelta
Deal found 28/8£663
Tue 9/910:05MAD - SCL
2 stops25h 55mDelta
Sun 15/223:15SCL - MAD
2 stops31h 00mDelta
Deal found 30/8£654
Sun 14/919:10MAD - SCL
2 stops21h 20mBritish Airways
Fri 26/916:00SCL - MAD
1 stop23h 05mBritish Airways
Deal found 28/8£665
Thu 18/910:05MAD - SCL
1 stop25h 55mDelta
Mon 29/921:40SCL - MAD
2 stops38h 05mDelta
Deal found 29/8£654
Thu 25/906:00MAD - SCL
2 stops30h 00mDelta
Thu 2/1021:40SCL - MAD
2 stops40h 40mDelta
Deal found 27/8£677
One-way flights from Madrid to Santiago
Search for one-way flight options from Madrid to Santiago. Find affordable one-way fares based on user searches. Data last updated 30 August 2025.
Thu 4/909:40MAD - SCL
1 stop18h 50mAvianca
Deal found 28/8£360
Fri 12/909:40MAD - SCL
1 stop18h 50mAvianca
Deal found 27/8£361
Wed 29/1005:55MAD - SCL
2 stops29h 55mUnited Airlines
Deal found 28/8£362
Thu 13/1106:00MAD - SCL
2 stops30h 50mUnited Airlines
Deal found 29/8£363
Sat 15/1108:25MAD - SCL
2 stops52h 25mUnited Airlines
Deal found 28/8£376
Mon 8/901:30MAD - SCL
1 stop32h 45mAvianca
Deal found 27/8£376
Mon 6/1001:30MAD - SCL
1 stop17h 55mAvianca
Deal found 28/8£419
Sun 1/201:20MAD - SCL
1 stop18h 00mAvianca
Deal found 28/8£419
Thu 23/1001:30MAD - SCL
1 stop17h 55mAvianca
Deal found 30/8£422
Tue 2/1216:20MAD - SCL
1 stop36h 10mAvianca
Deal found 28/8£434
Cheapflights Fare Finder
Customise your flight search to find flights from Madrid to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 30 August 2025.
Use the filters below to find and compare flights from Madrid to Santiago that are best for you.
Fly from
Madrid
Fly to
Santiago
Route
Depart
Return
Price
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Sun 28/12
06:00-06:10
2 stops28h 10m
Santiago Arturo Merino Benitez
Wed 14/1
23:15-12:10
2 stops32h 55m
£654
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Fri 24/10
10:05-07:00
1 stop25h 55m
Santiago Arturo Merino Benitez
Wed 29/10
22:10-08:05
1 stop29h 55m
£654
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Sat 31/1
11:00-07:00
1 stop24h 00m
Santiago Arturo Merino Benitez
Thu 5/2
23:15-09:00
1 stop29h 45m
£654
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Thu 18/9
06:00-07:00
2 stops30h 00m
Santiago Arturo Merino Benitez
Mon 29/9
21:40-09:35
1 stop30h 55m
£654
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Fri 24/10
06:00-07:00
2 stops30h 00m
Santiago Arturo Merino Benitez
Tue 18/11
23:10-10:15
2 stops31h 05m
£654
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Tue 3/2
11:00-07:00
1 stop24h 00m
Santiago Arturo Merino Benitez
Thu 5/2
23:15-09:00
1 stop29h 45m
£654
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Mon 2/2
10:00-07:00
2 stops49h 00m
Santiago Arturo Merino Benitez
Thu 5/2
23:15-09:00
1 stop29h 45m
£654
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Fri 24/10
06:00-07:00
2 stops30h 00m
Santiago Arturo Merino Benitez
Fri 28/11
23:10-09:15
1 stop30h 05m
£654
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Sun 1/2
10:00-07:00
2 stops49h 00m
Santiago Arturo Merino Benitez
Thu 5/2
23:15-09:00
1 stop29h 45m
£654
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Thu 4/9
09:40-22:30
1 stop18h 50m
£360
Flights are sorted by cheapest return flights first.
Deals found on 28/8
Showing 1-10 of 19 results
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Best time to book a flight from Madrid to Santiago
Have a flexible travel schedule? Discover the best time to fly to Santiago from Madrid with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Madrid to Santiago
Prices
Airlines
How far ahead should I book a flight from Madrid to Santiago?
Use this chart to determine the optimal time to book a return flight from Madrid to Santiago. Price data was last updated on 29 August 2025.
The price you pay for your flight from Madrid to Santiago may vary depending on when you book. For the best chance of a lower fare, look to book 88 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Madrid to Santiago?
Currently, May is the cheapest month in which you can book a flight from Madrid to Santiago (average of £1,031). Flying from Madrid to Santiago in December is currently the most expensive (average of £1,468). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MAD to SCL?
Find hourly flight availability from Madrid to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 30 August 2025.
A simple way to save on the total cost of your ticket is to fly from Madrid to Santiago in the afternoon. If you’re flexible enough to do this you can expect to save up to 30% on your trip compared to booking a flight at midday.
How much does it cost for a return flight from Madrid to Santiago?
Weekly flight availability from Madrid to Santiago
Explore weekly flight availability from Madrid to Santiago. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated 30 August 2025.
The most flights from MAD to SCL are scheduled on a Friday (18 on average). You will have fewer flight options on Wednesday, which is when the least amount of flights are scheduled (9 on average).
Reviews of airlines servicing Santiago
Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated 30 August 2025.
Read through reviews of airlines operating flights from Madrid to Santiago, such as Iberia and British Airways. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Our flight kept getting delayed due to the weather and mechanical issues. Then it was canceled and rescheduled until the following day which was also delayed by a couple hours and the returning flight was also delayed so overall, we wasted a lot of time on the airport. Also, when it happened the first day, they did not want to honor a hotel or rideshare service voucher because it was hard to find an uber at 3-4 in the morning and customer service was closed that late in the day.
Our flight kept getting delayed due to the weather and mechanical issues. Then it was canceled and rescheduled until the following day which was also delayed by a couple hours and the returning flight was also delayed so overall, we wasted a lot of time on the airport. Also, when it happened the first day, they did not want to honor a hotel or rideshare service voucher because it was hard to find an uber at 3-4 in the morning and customer service was closed that late in the day.
Our flight kept getting delayed due to the weather and mechanical issues. Then it was canceled and rescheduled until the following day which was also delayed by a couple hours and the returning flight was also delayed so overall, we wasted a lot of time on the airport. Also, when it happened the first day, they did not want to honor a hotel or rideshare service voucher because it was hard to find an uber at 3-4 in the morning and customer service was closed that late in the day.
Related info for your journey
Find useful and relevant information for your journey from Madrid to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
What airports do I use to fly from Madrid to Santiago?
To fly from Madrid to Santiago, you need to book a flight from Barajas (MAD) to Arturo Merino Benitez (SCL). Nonstop flights to Santiago Arturo Merino Benitez from Madrid Barajas take 13h 15m on average. When it comes time to book airfare, you have a few options: there are 14 outbound flights from Barajas to Arturo Merino Benitez offered by 2 different airlines.
How popular is this Madrid to Santiago flight route?
This flight path from Madrid Barajas to Santiago Arturo Merino Benitez was viewed by 6 users in the past month. Keep an eye out for changes in search interest prior to high and low season.
How long is the flight from Madrid to Santiago?
A quick flight from Madrid to Santiago can take about 25h 55m. Delta provides one of the quickest options available for as low as £654. Airlines will cover a distance of 6656 mi.
What are the cheapest airlines flying from Madrid to Santiago round-trip?
Cheapflights users have booked flights from Madrid to Santiago round-trip from £452. Another airline that can offer you cheap pricing is British Airways. Users have found that Iberia is 43% cheaper than the other options available to this destination.
What are the most reliable airlines from Madrid to Santiago?
No one likes to see their flight delayed. When booking a flight from Madrid to Santiago consider choosing Finnair (87%), Japan Airlines (82%) or EL AL (80%) as they are the most reliable in getting you off to your destination on time.
What are the cheapest flights from Madrid to Santiago?
Looking at all options, your cheapest flight can be booked for £441. While the most popular route (Madrid Barajas - Santiago Arturo Merino Benitez) can be booked for £603 on average our data indicates £737 when flying from Madrid to Santiago.
Can I find deals for business class flights from Madrid to Santiago?
Yes. Cheapflights offers flight deals from Madrid to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Madrid to Santiago?
Currently, May is the cheapest month in which you can book a flight from Madrid to Santiago (average of £1,031). Flying from Madrid to Santiago in December is currently the most expensive (average of £1,468). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Explore flights to Santiago departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on 30 August 2025.
Discover the top 2 airlines that operate flights from Madrid to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 30 August 2025.
Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.
How does Cheapflights help users find flights from Madrid to Santiago?
Cheapflights makes it easy to find Madrid to Santiago flights by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.
Why should you use Cheapflights to find cheap flight tickets from Madrid to Santiago?
Millions of users choose and trust Cheapflights to book the best flight deals from Madrid to Santiago for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.
Can Cheapflights find flights from Madrid to Santiago with no change fees?
Certainly. Search results for flights to Santiago from Madrid shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.
Can Cheapflights notify me if prices for flights from Madrid to Santiago become cheaper?
Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!
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