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Cheap flights from Madrid, Spain to Santiago from £360

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/9. Fares are subject to change and may not be available on all flights or dates of travel.
MAD — SCL
4 Sep — 11 Sep1
1 adult

Cheapflights Tip: The best prices from Madrid Barajas to Santiago Arturo Merino Benitez are usually found in March or April, booked 88 days in advance, depart on a Friday or Wednesday and return on a Monday

Cheap flight deals from Madrid to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Madrid (MAD) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 30 August 2025.

Round-trip from

£654

One-way from

£360

Popular in

December

Cheapest in

March

Average price

£940

Good round-trip deal

£970 or less

Good one-way deal

£478 or less
Delta
  • Delta
  • 18/9-29/9
  • 3 total stops
  • 64h 00m total
  • Madrid to Santiago
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Avianca
  • Avianca
  • 4/9
  • 1 total stop
  • 18h 50m total
  • Madrid to Santiago
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Highest demand for flights based on searches. 5% potential increase in price (£31 potential increase over avg. return price).
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Cheapest flight prices on average. 2% potential price decrease (£15 potential savings vs. average return price).
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Average for round-trip flights in August 2025
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Price to beat on a round-trip flight from Madrid Barajas to Santiago Arturo Merino Benitez.
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Price to beat on a one-way flight from Madrid Barajas to Santiago Arturo Merino Benitez.
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Find flight deals from Madrid to Santiago

Cheapest flights from Madrid to Santiago
Explore the most affordable flight options available from Madrid to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 30 August 2025.

Sun 31/806:00MAD - SCL
2 stops31h 00mDelta
Tue 23/921:40SCL - MAD
2 stops37h 45mDelta
Deal found 28/8£651
Thu 18/910:05MAD - SCL
1 stop25h 55mDelta
Mon 29/921:40SCL - MAD
2 stops38h 05mDelta
Deal found 29/8£654
Fri 24/1006:00MAD - SCL
2 stops30h 00mDelta
Fri 28/1123:10SCL - MAD
1 stop30h 05mDelta
Deal found 28/8£654
Thu 13/1106:00MAD - SCL
2 stops30h 50mUnited Airlines
Thu 4/1222:45SCL - MAD
2 stops53h 20mUnited Airlines
Deal found 28/8£656
Tue 7/1007:30MAD - SCL
2 stops28h 30mDelta
Sat 25/1021:40SCL - MAD
1 stop30h 25mDelta
Deal found 29/8£657
Thu 23/1006:00MAD - SCL
2 stops30h 00mDelta
Thu 6/1123:10SCL - MAD
1 stop30h 05mDelta
Deal found 29/8£657
Mon 24/1111:15MAD - SCL
1 stop24h 25mDelta
Thu 27/1123:10SCL - MAD
1 stop28h 50mDelta
Deal found 30/8£658
Thu 4/912:40MAD - SCL
2 stops24h 20mDelta
Thu 2/1021:40SCL - MAD
2 stops40h 40mDelta
Deal found 27/8£660
Wed 19/1106:00MAD - SCL
2 stops29h 40mDelta
Tue 3/323:15SCL - MAD
2 stops36h 50mDelta
Deal found 29/8£661
Wed 8/1006:00MAD - SCL
2 stops30h 00mDelta
Wed 5/1123:10SCL - MAD
1 stop30h 05mDelta
Deal found 28/8£663
Thu 9/1006:00MAD - SCL
2 stops30h 00mDelta
Tue 14/1021:40SCL - MAD
2 stops53h 10mDelta
Deal found 28/8£663
Sun 7/915:10MAD - SCL
2 stops44h 50mDelta
Sun 15/223:15SCL - MAD
2 stops28h 45mDelta
Deal found 30/8£664

Cheapflights Fare Finder

 
Customise your flight search to find flights from Madrid to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 30 August 2025.
Use the filters below to find and compare flights from Madrid to Santiago that are best for you.

Fly from

Madrid

Fly to

Santiago

Route

Depart

Return

Price

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Sun 28/12

06:00-06:10

2 stops28h 10m

Santiago Arturo Merino Benitez

Wed 14/1

23:15-12:10

2 stops32h 55m

£654

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Fri 24/10

10:05-07:00

1 stop25h 55m

Santiago Arturo Merino Benitez

Wed 29/10

22:10-08:05

1 stop29h 55m

£654

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Sat 31/1

11:00-07:00

1 stop24h 00m

Santiago Arturo Merino Benitez

Thu 5/2

23:15-09:00

1 stop29h 45m

£654

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Thu 18/9

06:00-07:00

2 stops30h 00m

Santiago Arturo Merino Benitez

Mon 29/9

21:40-09:35

1 stop30h 55m

£654

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Fri 24/10

06:00-07:00

2 stops30h 00m

Santiago Arturo Merino Benitez

Tue 18/11

23:10-10:15

2 stops31h 05m

£654

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Tue 3/2

11:00-07:00

1 stop24h 00m

Santiago Arturo Merino Benitez

Thu 5/2

23:15-09:00

1 stop29h 45m

£654

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Mon 2/2

10:00-07:00

2 stops49h 00m

Santiago Arturo Merino Benitez

Thu 5/2

23:15-09:00

1 stop29h 45m

£654

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Fri 24/10

06:00-07:00

2 stops30h 00m

Santiago Arturo Merino Benitez

Fri 28/11

23:10-09:15

1 stop30h 05m

£654

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Sun 1/2

10:00-07:00

2 stops49h 00m

Santiago Arturo Merino Benitez

Thu 5/2

23:15-09:00

1 stop29h 45m

£654

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Thu 4/9

09:40-22:30

1 stop18h 50m

£360

Flights are sorted by cheapest return flights first.

Deals found on 28/8

Showing 1-10 of 19 results
1
2

Best time to book a flight from Madrid to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Madrid with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Madrid to Santiago

How far ahead should I book a flight from Madrid to Santiago?

Use this chart to determine the optimal time to book a return flight from Madrid to Santiago. Price data was last updated on 29 August 2025.

The price you pay for your flight from Madrid to Santiago may vary depending on when you book. For the best chance of a lower fare, look to book 88 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Madrid to Santiago?

Currently, May is the cheapest month in which you can book a flight from Madrid to Santiago (average of £1,031). Flying from Madrid to Santiago in December is currently the most expensive (average of £1,468). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MAD to SCL?

Find hourly flight availability from Madrid to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 30 August 2025.

A simple way to save on the total cost of your ticket is to fly from Madrid to Santiago in the afternoon. If you’re flexible enough to do this you can expect to save up to 30% on your trip compared to booking a flight at midday.

How much does it cost for a return flight from Madrid to Santiago?

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated 30 August 2025.
Read through reviews of airlines operating flights from Madrid to Santiago, such as Iberia and British Airways. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Iberia
7.0
Good
2,894 reviews
Check prices

Comfort

6.7

Food

6.3

Entertainment

6.6

Crew

7.6

Boarding

7.1

Overall

7.0

Reviews

1 / 20
2.0
Mediocre

Gaby,Aug 2025

BCN - ORD

Our flight kept getting delayed due to the weather and mechanical issues. Then it was canceled and rescheduled until the following day which was also delayed by a couple hours and the returning flight was also delayed so overall, we wasted a lot of time on the airport. Also, when it happened the first day, they did not want to honor a hotel or rideshare service voucher because it was hard to find an uber at 3-4 in the morning and customer service was closed that late in the day.
Iberia
7.0
Good
2,894 reviews
Iberia
7.0
Good
2,894 reviews
Check prices

Comfort

6.7

Food

6.3

Entertainment

6.6

Crew

7.6

Boarding

7.1

Overall

7.0

Reviews

1 / 20
2.0
Mediocre

Gaby,Aug 2025

BCN - ORD

Our flight kept getting delayed due to the weather and mechanical issues. Then it was canceled and rescheduled until the following day which was also delayed by a couple hours and the returning flight was also delayed so overall, we wasted a lot of time on the airport. Also, when it happened the first day, they did not want to honor a hotel or rideshare service voucher because it was hard to find an uber at 3-4 in the morning and customer service was closed that late in the day.
British Airways
6.7
Okay
7,327 reviews
Iberia
7.0
Good
2,894 reviews
Check prices

Comfort

6.7

Food

6.3

Entertainment

6.6

Crew

7.6

Boarding

7.1

Overall

7.0

Reviews

1 / 20
2.0
Mediocre

Gaby,Aug 2025

BCN - ORD

Our flight kept getting delayed due to the weather and mechanical issues. Then it was canceled and rescheduled until the following day which was also delayed by a couple hours and the returning flight was also delayed so overall, we wasted a lot of time on the airport. Also, when it happened the first day, they did not want to honor a hotel or rideshare service voucher because it was hard to find an uber at 3-4 in the morning and customer service was closed that late in the day.

Related info for your journey

Find useful and relevant information for your journey from Madrid to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Madrid to Santiago?

    To fly from Madrid to Santiago, you need to book a flight from Barajas (MAD) to Arturo Merino Benitez (SCL). Nonstop flights to Santiago Arturo Merino Benitez from Madrid Barajas take 13h 15m on average. When it comes time to book airfare, you have a few options: there are 14 outbound flights from Barajas to Arturo Merino Benitez offered by 2 different airlines.

  • How popular is this Madrid to Santiago flight route?

    This flight path from Madrid Barajas to Santiago Arturo Merino Benitez was viewed by 6 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Madrid to Santiago?

    A quick flight from Madrid to Santiago can take about 25h 55m. Delta provides one of the quickest options available for as low as £654. Airlines will cover a distance of 6656 mi.

  • What are the cheapest airlines flying from Madrid to Santiago round-trip?

    Cheapflights users have booked flights from Madrid to Santiago round-trip from £452. Another airline that can offer you cheap pricing is British Airways. Users have found that Iberia is 43% cheaper than the other options available to this destination.

  • What are the most reliable airlines from Madrid to Santiago?

    No one likes to see their flight delayed. When booking a flight from Madrid to Santiago consider choosing Finnair (87%), Japan Airlines (82%) or EL AL (80%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Madrid to Santiago?

    Looking at all options, your cheapest flight can be booked for £441. While the most popular route (Madrid Barajas - Santiago Arturo Merino Benitez) can be booked for £603 on average our data indicates £737 when flying from Madrid to Santiago.

  • Can I find deals for flights from Madrid to Santiago that include hotel bookings?

    Yes. In addition to deals on Madrid to Santiago flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Madrid to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Madrid to Santiago.

  • Can I find deals for business class flights from Madrid to Santiago?

    Yes. Cheapflights offers flight deals from Madrid to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Madrid to Santiago?

    Currently, May is the cheapest month in which you can book a flight from Madrid to Santiago (average of £1,031). Flying from Madrid to Santiago in December is currently the most expensive (average of £1,468). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Complete your trip

Complete your trip to Santiago by adding a car hire and/or hotel booking to your travel itinerary.
Santiago car hire
Santiago Arturo Merino Benitez Airport car hire
Punta Arenas car hire
Balmaceda car hire
Puerto Montt car hire
Lastarria car hire

Top 2 airlines flying from Madrid to Santiago

Discover the top 2 airlines that operate flights from Madrid to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 30 August 2025.
AirlineCheapestAverageFlexibilityOn-time
IberiaCheapest£452Average£883FlexibilityNo cancel feeOn-time77%
Search Iberia flights
British AirwaysCheapest£513Average£546FlexibilityNo cancel feeOn-time70%
Search British Airways flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Madrid to Santiago?

Cheapflights makes it easy to find Madrid to Santiago flights by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

Why should you use Cheapflights to find cheap flight tickets from Madrid to Santiago?

Millions of users choose and trust Cheapflights to book the best flight deals from Madrid to Santiago for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.

Can Cheapflights find flights from Madrid to Santiago with no change fees?

Certainly. Search results for flights to Santiago from Madrid shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Madrid to Santiago become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

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