Cheap flights from Madrid, Spain to Santiago from £425
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/12. Fares are subject to change and may not be available on all flights or dates of travel.
MAD — SCL
4 Dec — 11 Dec1
Return
1 adult
Economy
Return
1 adult, Economy, 0 bags
Cheapflights Tip: The best prices from Madrid Barajas to Santiago Arturo Merino Benitez are usually found in March or February, booked 88 days in advance, depart on a Wednesday or Thursday and return on a Wednesday
Find flight deals from Madrid to Santiago
Enter your travel dates to find the best prices.
Cheapest flights from Madrid to Santiago
Explore the most affordable flight options available from Madrid to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 4 November 2025.
Mon 24/1111:15MAD - SCL
1 stop24h 25mDelta
Sun 7/1223:10SCL - MAD
2 stops28h 50mDelta
Deal found 3/11£626
Thu 4/1211:15MAD - SCL
1 stop24h 25mDelta
Sun 1/223:10SCL - MAD
2 stops36h 10mDelta
Deal found 3/11£630
Thu 27/1106:00MAD - SCL
2 stops29h 40mDelta
Wed 3/1223:10SCL - MAD
2 stops28h 50mDelta
Deal found 3/11£642
Thu 13/1111:15MAD - SCL
1 stop24h 25mDelta
Fri 28/1123:10SCL - MAD
2 stops31h 05mDelta
Deal found 3/11£647
Wed 12/1111:05MAD - SCL
2 stops49h 45mUnited Airlines
Mon 17/1122:45SCL - MAD
2 stops30h 30mUnited Airlines
Deal found 3/11£651
Mon 10/1106:00MAD - SCL
2 stops29h 40mDelta
Mon 24/1123:10SCL - MAD
2 stops38h 30mDelta
Deal found 3/11£656
Wed 26/1111:15MAD - SCL
1 stop24h 25mDelta
Fri 5/1223:10SCL - MAD
1 stop30h 05mDelta
Deal found 2/11£658
Tue 25/1111:15MAD - SCL
1 stop24h 25mDelta
Fri 5/1223:10SCL - MAD
1 stop30h 05mDelta
Deal found 3/11£661
Mon 24/1111:15MAD - SCL
2 stops25h 35mUnited Airlines
Sun 7/1222:45SCL - MAD
2 stops30h 30mUnited Airlines
Deal found 3/11£664
Wed 19/1110:00MAD - SCL
2 stops25h 40mDelta
Sun 23/1123:10SCL - MAD
1 stop30h 05mDelta
Deal found 3/11£668
Best flights from Madrid to Santiago
Discover carefully curated flight deals from Madrid to Santiago that have cost, travel time, and stopovers in mind to ensure you get the best travel experience. Data last updated 4 November 2025.
Thu 4/1211:15MAD - SCL
1 stop24h 25mDelta
Sun 1/223:10SCL - MAD
2 stops36h 10mDelta
Deal found 3/11£630
Fri 17/413:20MAD - SCL
Nonstop13h 20mIberia
Sun 3/510:55SCL - MAD
Nonstop12h 40mIberia
Deal found 2/11£655
Tue 17/206:00MAD - SCL
2 stops29h 00mDelta
Wed 25/223:15SCL - MAD
2 stops28h 45mDelta
Deal found 3/11£634
Thu 27/1111:15MAD - SCL
1 stop24h 25mDelta
Wed 3/1223:10SCL - MAD
2 stops28h 50mDelta
Deal found 3/11£660
Wed 26/1111:15MAD - SCL
1 stop24h 25mDelta
Sun 7/1223:10SCL - MAD
1 stop30h 05mDelta
Deal found 3/11£661
Thu 27/1111:15MAD - SCL
1 stop24h 25mDelta
Thu 4/1221:30SCL - MAD
1 stop31h 45mDelta
Deal found 3/11£661
Tue 25/1111:15MAD - SCL
1 stop24h 25mDelta
Wed 3/1223:10SCL - MAD
1 stop30h 05mDelta
Deal found 3/11£661
Thu 27/1111:15MAD - SCL
1 stop24h 25mDelta
Fri 5/1223:10SCL - MAD
1 stop30h 05mDelta
Deal found 3/11£661
Tue 25/1111:15MAD - SCL
1 stop24h 25mDelta
Fri 5/1223:10SCL - MAD
1 stop30h 05mDelta
Deal found 3/11£661
Wed 11/310:05MAD - SCL
1 stop24h 55mDelta
Tue 24/323:15SCL - MAD
2 stops38h 25mDelta
Deal found 4/11£674
Direct flights from Madrid to Santiago
Explore direct flight options from Madrid to Santiago based on user searches, and compare prices and availability for your desired travel dates. Data last updated 4 November 2025.
Fri 3/413:20MAD - SCL
Nonstop13h 20mIberia
Mon 13/410:55SCL - MAD
Nonstop12h 40mIberia
Deal found 3/11£655
Sun 15/312:55MAD - SCL
Nonstop13h 20mIberia
Mon 30/311:55SCL - MAD
Nonstop12h 40mIberia
Deal found 2/11£657
Wed 1/423:59MAD - SCL
Nonstop13h 26mIberia
Thu 30/410:55SCL - MAD
Nonstop12h 40mIberia
Deal found 2/11£684
Tue 31/323:59MAD - SCL
Nonstop13h 26mIberia
Tue 21/422:20SCL - MAD
Nonstop12h 40mIberia
Deal found 3/11£689
Thu 23/423:59MAD - SCL
Nonstop13h 26mIberia
Sat 9/510:55SCL - MAD
Nonstop12h 40mIberia
Deal found 3/11£743
Thu 20/1123:59MAD - SCL
Nonstop13h 21mIberia
Sun 30/1123:55SCL - MAD
Nonstop12h 40mIberia
Deal found 2/11£837
Sun 1/223:59MAD - SCL
Nonstop13h 21mIberia
Fri 13/223:55SCL - MAD
Nonstop12h 40mIberia
Deal found 2/11£843
Tue 13/112:55MAD - SCL
Nonstop13h 20mIberia
Thu 5/213:05SCL - MAD
Nonstop12h 35mIberia
Deal found 3/11£875
Mon 16/323:35MAD - SCL
Nonstop13h 15mLATAM Airlines
Thu 19/321:00SCL - MAD
Nonstop13h 00mLATAM Airlines
Deal found 3/11£887
Wed 26/1112:55MAD - SCL
Nonstop13h 20mLATAM Airlines
Wed 10/1221:00SCL - MAD
Nonstop13h 00mLATAM Airlines
Deal found 3/11£910
Sun 30/1123:35MAD - SCL
Nonstop13h 15mLATAM Airlines
Wed 10/1221:00SCL - MAD
Nonstop13h 00mLATAM Airlines
Deal found 3/11£954
Last-minute flights from Madrid to Santiago
Discover last-minute flight deals from Madrid to Santiago. Data last updated 4 November 2025 and is based on user searches.
Mon 10/1106:00MAD - SCL
2 stops29h 40mDelta
Mon 24/1123:10SCL - MAD
2 stops38h 30mDelta
Deal found 3/11£656
Wed 12/1111:05MAD - SCL
2 stops49h 45mUnited Airlines
Mon 17/1122:45SCL - MAD
2 stops30h 30mUnited Airlines
Deal found 3/11£651
Thu 13/1111:15MAD - SCL
1 stop24h 25mDelta
Fri 28/1123:10SCL - MAD
2 stops31h 05mDelta
Deal found 3/11£647
Wed 19/1110:00MAD - SCL
2 stops25h 40mDelta
Sun 23/1123:10SCL - MAD
1 stop30h 05mDelta
Deal found 3/11£668
Mon 24/1111:15MAD - SCL
1 stop24h 25mDelta
Sun 7/1223:10SCL - MAD
2 stops28h 50mDelta
Deal found 3/11£626
Mon 24/1111:15MAD - SCL
2 stops25h 35mUnited Airlines
Sun 7/1222:45SCL - MAD
2 stops30h 30mUnited Airlines
Deal found 3/11£664
Tue 25/1111:15MAD - SCL
1 stop24h 25mDelta
Fri 5/1223:10SCL - MAD
1 stop30h 05mDelta
Deal found 3/11£661
Wed 26/1111:15MAD - SCL
1 stop24h 25mDelta
Sun 7/1223:10SCL - MAD
1 stop30h 05mDelta
Deal found 2/11£658
Thu 27/1106:00MAD - SCL
2 stops29h 40mDelta
Wed 3/1223:10SCL - MAD
2 stops28h 50mDelta
Deal found 3/11£642
Thu 4/1211:15MAD - SCL
1 stop24h 25mDelta
Sun 1/223:10SCL - MAD
2 stops36h 10mDelta
Deal found 3/11£630
One-way flights from Madrid to Santiago
Search for one-way flight options from Madrid to Santiago. Find affordable one-way fares based on user searches. Data last updated 4 November 2025.
Wed 3/1216:30MAD - SCL
3 stops57h 45mMultiple Airlines
Deal found 3/11£425
Mon 29/1211:05MAD - SCL
Nonstop13h 25mLATAM Airlines
Deal found 3/11£430
Fri 5/1211:05MAD - SCL
Nonstop13h 25mLATAM Airlines
Deal found 3/11£432
Tue 2/1222:55MAD - SCL
1 stop16h 40mLATAM Airlines
Deal found 3/11£434
Wed 22/413:20MAD - SCL
Nonstop13h 20mIberia
Deal found 3/11£438
Sun 23/1111:05MAD - SCL
2 stops49h 45mUnited Airlines
Deal found 3/11£438
Wed 19/1111:15MAD - SCL
2 stops25h 35mUnited Airlines
Deal found 2/11£441
Sat 28/206:40MAD - SCL
1 stop26h 50mAvianca
Deal found 3/11£443
Thu 1/110:50MAD - SCL
1 stop22h 40mAvianca
Deal found 3/11£444
Sat 6/1211:05MAD - SCL
Nonstop13h 25mLATAM Airlines
Deal found 3/11£446
Thu 4/1218:00MAD - SCL
3 stops48h 40mMultiple Airlines
Deal found 3/11£449
Cheap flight deals from Madrid to Santiago
Discover tips and strategies to find the most affordable flight options for your journey from Madrid (MAD) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 4 November 2025.
Customise your flight search to find flights from Madrid to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 4 November 2025.
Use the filters below to find and compare flights from Madrid to Santiago that are best for you.
Fly from
Madrid
Fly to
Santiago
Route
Depart
Return
Price
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Thu 4/12
11:15-07:40
1 stop24h 25m
Santiago Arturo Merino Benitez
Sun 1/2
23:10-15:20
2 stops36h 10m
£630
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Tue 17/2
06:00-07:00
2 stops29h 00m
Santiago Arturo Merino Benitez
Wed 25/2
23:15-08:00
2 stops28h 45m
£634
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Fri 17/4
13:20-20:40
Nonstop13h 20m
Santiago Arturo Merino Benitez
Sun 3/5
10:55-05:35
Nonstop12h 40m
£655
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Thu 27/11
11:15-07:40
1 stop24h 25m
Santiago Arturo Merino Benitez
Wed 3/12
23:10-08:00
2 stops28h 50m
£660
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Wed 26/11
11:15-07:40
1 stop24h 25m
Santiago Arturo Merino Benitez
Sun 7/12
23:10-09:15
1 stop30h 05m
£661
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Thu 27/11
11:15-07:40
1 stop24h 25m
Santiago Arturo Merino Benitez
Thu 4/12
21:30-09:15
1 stop31h 45m
£661
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Tue 25/11
11:15-07:40
1 stop24h 25m
Santiago Arturo Merino Benitez
Wed 3/12
23:10-09:15
1 stop30h 05m
£661
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Thu 27/11
11:15-07:40
1 stop24h 25m
Santiago Arturo Merino Benitez
Fri 5/12
23:10-09:15
1 stop30h 05m
£661
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Tue 25/11
11:15-07:40
1 stop24h 25m
Santiago Arturo Merino Benitez
Fri 5/12
23:10-09:15
1 stop30h 05m
£661
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Wed 11/3
10:05-07:00
1 stop24h 55m
Santiago Arturo Merino Benitez
Tue 24/3
23:15-17:40
2 stops38h 25m
£674
Flights are sorted by cheapest return flights first.
Deals found on 3/11
Showing 1-10 of 20 results
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Best time to book a flight from Madrid to Santiago
Have a flexible travel schedule? Discover the best time to fly to Santiago from Madrid with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Madrid to Santiago
Prices
Airlines
Delays
How far ahead should I book a flight from Madrid to Santiago?
Use this chart to determine the optimal time to book a return flight from Madrid to Santiago. Price data was last updated on 31 October 2025.
The price you pay for your flight from Madrid to Santiago may vary depending on when you book. For the best chance of a lower fare, look to book 88 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Madrid to Santiago?
Currently, January is the cheapest month in which you can book a flight from Madrid to Santiago (average of £443). Flying from Madrid to Santiago in July is currently the most expensive (average of £676). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MAD to SCL?
Find hourly flight availability from Madrid to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 4 November 2025.
A simple way to save on the total cost of your ticket is to fly from Madrid to Santiago in the morning. If you’re flexible enough to do this you can expect to save up to 11% on your trip compared to booking a flight in the afternoon.
Weekly flight availability from Madrid to Santiago
Explore weekly flight availability from Madrid to Santiago. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated 4 November 2025.
The most flights from MAD to SCL are scheduled on a Monday (15 on average). You will have fewer flight options on Thursday, which is when the least amount of flights are scheduled (10 on average).
How often are flights from Madrid to Santiago delayed?
About 10% of weekly flights between Madrid and Santiago have experienced delays in the past year, with the average delay time being 142 minutes.
What is the most punctual flight time for Madrid to Santiago flights?
Historically, flights departing in the evening are less likely to be delayed, whereas flights leaving in the early afternoon tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Saturday tends to have the lowest number of delays on this route, whereas Sunday has historically faced a higher average of delays compared to other days of the week.
Which airline has the best punctuality record on Madrid to Santiago flights?
Over the past year, Finnair have had the lowest number of delays on this route, with just 6% of flights being delayed.
Reviews of airlines servicing Santiago
Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated 4 November 2025.
Read through reviews of airlines operating flights from Madrid to Santiago, such as LATAM Airlines, Iberia, andBritish Airways. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Terrible baggage service! Almost lost my connection flight in SP
Related info for your journey
Find useful and relevant information for your journey from Madrid to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
What airports do I use to fly from Madrid to Santiago?
To fly from Madrid to Santiago, you need to book a flight from Barajas (MAD) to Arturo Merino Benitez (SCL). Nonstop flights to Santiago Arturo Merino Benitez from Madrid Barajas take 13h 15m on average. When it comes time to book airfare, you have a few options: there are 13 outbound flights from Barajas to Arturo Merino Benitez offered by 3 different airlines.
How popular is this Madrid to Santiago flight route?
This flight path from Madrid Barajas to Santiago Arturo Merino Benitez was viewed by 12 users in the past month. Keep an eye out for changes in search interest prior to high and low season.
How long is the flight from Madrid to Santiago?
A quick flight from Madrid to Santiago can take about 24h 25m. Delta provides one of the quickest options available for as low as £630. Airlines will cover a distance of 6656 mi.
What are the cheapest airlines flying from Madrid to Santiago round-trip?
Cheapflights users have booked flights from Madrid to Santiago round-trip from £464. Other airlines that can offer you cheap pricing are LATAM Airlines, from £524, and British Airways, from £527. Users have found that Iberia is 43% cheaper than the other options available to this destination.
What are the cheapest airlines to fly from Madrid to Santiago one-way?
To fly one-way, consider booking your trip with LATAM Airlines, which is currently one of the cheapest options available, starting at £430. United Airlines flights start at £438 while deals on Avianca start at £443 one-way.
What are the most reliable airlines from Madrid to Santiago?
No one likes to see their flight delayed. When booking a flight from Madrid to Santiago consider choosing Japan Airlines (87%), EL AL (87%) or Finnair (86%) as they are the most reliable in getting you off to your destination on time.
What are the cheapest flights from Madrid to Santiago?
Looking at all options, your cheapest flight can be booked for £437. While the most popular route (Madrid Barajas - Santiago Arturo Merino Benitez) can be booked for £630 on average, our data indicates £630 when flying from Madrid to Santiago.
Can I find deals for business class flights from Madrid to Santiago?
Yes. Cheapflights offers flight deals from Madrid to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Madrid to Santiago?
Currently, January is the cheapest month in which you can book a flight from Madrid to Santiago (average of £443). Flying from Madrid to Santiago in July is currently the most expensive (average of £676). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Explore flights to Santiago departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on 4 November 2025.
Discover the top 3 airlines that operate flights from Madrid to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 4 November 2025.
Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.
How does Cheapflights help users find flights from Madrid to Santiago?
Cheapflights makes it easy to find Madrid to Santiago flights by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.
Why should you use Cheapflights to find cheap flight tickets from Madrid to Santiago?
Millions of users choose and trust Cheapflights to book the best flight deals from Madrid to Santiago for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.
Can Cheapflights find flights from Madrid to Santiago with no change fees?
Certainly. Search results for flights to Santiago from Madrid shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.
Can Cheapflights notify me if prices for flights from Madrid to Santiago become cheaper?
Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!
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