Cheap flights from Madrid, Spain to Santiago from £418

MAD — SCL
10 Dec — 17 Dec1
1 adult
1 adult, Economy, 0 bags
Cheapflights Tip: The best prices from Madrid Barajas to Santiago Arturo Merino Benitez are usually found in May or March, booked 53 days in advance, depart on a Thursday or Saturday and return on a Sunday

Cheap flight deals from Madrid to Santiago

Enter your travel dates to find the best prices.

Cheapest flights from Madrid to Santiago

Thu 26/1109:20 -
2 stops26h 20m
Wed 9/1223:10 -
2 stops28h 10m
Deal found 8/11£673
Thu 19/1109:20 -
2 stops26h 20m
Wed 2/1223:10 -
2 stops28h 10m
Deal found 7/11£674
Tue 17/1109:20 -
2 stops26h 20m
Sun 29/1123:10 -
2 stops28h 10m
Deal found 7/11£675
Wed 11/1109:20 -
2 stops26h 20m
Wed 25/1123:10 -
2 stops28h 10m
Deal found 10/11£676
Thu 10/1209:20 -
2 stops26h 20m
Mon 1/223:10 -
2 stops28h 10m
Deal found 6/11£679
Thu 10/1209:20 -
2 stops26h 20m
Sun 28/223:10 -
2 stops34h 10m
Deal found 6/11£690
Wed 30/1208:10 -
1 stop20h 55m
Sun 18/406:40 -
1 stop20h 25m
Deal found 9/11£692
Fri 4/1209:20 -
2 stops26h 20m
Sat 30/123:00 -
2 stops36h 20m
Deal found 6/11£693
Tue 24/1109:20 -
2 stops26h 20m
Thu 18/223:10 -
1 stop30h 35m
Deal found 8/11£708
Mon 23/1109:20 -
2 stops26h 20m
Sun 6/1223:10 -
1 stop30h 35m
Deal found 8/11£709

Find flight deals from Madrid to Santiago

Round-trip from

£669

One-way from

£418

Popular in

July

Cheapest in

May

Average price

£776

Good round-trip deal

£871 or less

Good one-way deal

£717 or less
Avianca
  • Avianca
  • 17/3-11/4
  • 2 total stops
  • 35h 05m total
  • Madrid to Santiago
United Airlines
  • United Airlines
  • 9/12-31/12
  • 2 total stops
  • 49h 35m total
  • Madrid to Santiago
Highest demand for flights based on searches. 11% potential increase in price (£80 potential increase over avg. return price).
Cheapest flight prices on average. 3% potential price decrease (£19 potential savings vs. average return price).
Average for round-trip flights in November 2026
Price to beat on a round-trip flight from Madrid Barajas to Santiago Arturo Merino Benitez.
Price to beat on a one-way flight from Madrid Barajas to Santiago Arturo Merino Benitez.

Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Madrid to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

MadridSantiago

MAD Madrid Barajas - SCL Santiago Arturo Merino Benitez

MADSCL

Madrid Barajas

Mon 16/11

11:00-08:50

2 stops49h 50m

Santiago Arturo Merino Benitez

Wed 31/12

00:00-04:00

Nonstop0h 00m

£496

MadridSantiago

MAD Madrid Barajas - SCL Santiago Arturo Merino Benitez

MADSCL

Madrid Barajas

Tue 8/12

12:20-07:40

1 stop23h 20m

Santiago Arturo Merino Benitez

Wed 31/12

00:00-04:00

Nonstop0h 00m

£576

MadridSantiago

MAD Madrid Barajas - SCL Santiago Arturo Merino Benitez

MADSCL

Madrid Barajas

Wed 9/12

12:20-06:40

1 stop22h 20m

Santiago Arturo Merino Benitez

Wed 31/12

00:00-04:00

Nonstop0h 00m

£576

MadridSantiago

MAD Madrid Barajas - SCL Santiago Arturo Merino Benitez

MADSCL

Madrid Barajas

Thu 10/12

12:20-07:40

1 stop23h 20m

Santiago Arturo Merino Benitez

Wed 31/12

00:00-04:00

Nonstop0h 00m

£576

MadridSantiago

MAD Madrid Barajas - SCL Santiago Arturo Merino Benitez

MADSCL

Madrid Barajas

Tue 1/12

12:20-07:40

1 stop23h 20m

Santiago Arturo Merino Benitez

Wed 31/12

00:00-04:00

Nonstop0h 00m

£577

MadridSantiago

MAD Madrid Barajas - SCL Santiago Arturo Merino Benitez

MADSCL

Madrid Barajas

Wed 23/12

12:20-07:40

1 stop23h 20m

Santiago Arturo Merino Benitez

Wed 31/12

00:00-04:00

Nonstop0h 00m

£577
Fastest return journey

MadridSantiago

MAD Madrid Barajas - SCL Santiago Arturo Merino Benitez

MADSCL

Madrid Barajas

Tue 12/1

13:55-07:40

1 stop21h 45m

Santiago Arturo Merino Benitez

Wed 31/12

00:00-04:00

Nonstop0h 00m

£578

MadridSantiago

MAD Madrid Barajas - SCL Santiago Arturo Merino Benitez

MADSCL

Madrid Barajas

Wed 2/12

12:20-07:40

1 stop23h 20m

Santiago Arturo Merino Benitez

Wed 31/12

00:00-04:00

Nonstop0h 00m

£578

MadridSantiago

MAD Madrid Barajas - SCL Santiago Arturo Merino Benitez

MADSCL

Madrid Barajas

Thu 24/12

12:20-07:40

1 stop23h 20m

Santiago Arturo Merino Benitez

Wed 31/12

00:00-04:00

Nonstop0h 00m

£579

MadridSantiago

MAD Madrid Barajas - SCL Santiago Arturo Merino Benitez

MADSCL

Madrid Barajas

Sun 15/11

11:15-08:50

2 stops49h 35m

Santiago Arturo Merino Benitez

Wed 31/12

00:00-04:00

Nonstop0h 00m

£581

Flights are sorted by cheapest return flights first.

Deals found on 5/11

Showing 1-10 of 21 resultsSorted by cheapest first
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Best time to book a flight from Madrid to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Madrid with our price prediction graph.
Estimated return price

Cheapflights Insights

Everything you need to know about your flight from Madrid to Santiago

How far ahead should I book a flight from Madrid to Santiago?

The price you pay for your flight from Madrid to Santiago may vary depending on when you book. For the best chance of a lower fare, look to book 52 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Madrid to Santiago?

Currently, May is the cheapest month in which you can book a flight from Madrid to Santiago (average of £683). Flying from Madrid to Santiago in July is currently the most expensive (average of £1,099). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MAD to SCL?

When flying from Madrid to Santiago, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

How much does it cost for a return flight from Madrid to Santiago?

Airfare is typical for this route at the moment.

Madrid to Santiago flights typically cost between £669 and £927 in March.
The cheapest return price found within the last 5 days was £669 on Multiple Airlines (17 Mar–11 Apr).

Reviews of airlines servicing Santiago

Read through reviews of airlines operating flights from Madrid to Santiago, such as Iberia. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Crew

7.7

Boarding

7.2

Entertainment

6.6

Overall

7.0

Food

6.4

Comfort

6.8

Reviews

1 / 20
10.0
Excellent

Silvia,Sept 2026

MAD - VCE

Smooth boarding, take off on time and landing ahead of schedule. Clean aircraft and nice crew.

Crew

7.7

Boarding

7.2

Entertainment

6.6

Overall

7.0

Food

6.4

Comfort

6.8

Reviews

1 / 20
10.0
Excellent

Silvia,Sept 2026

MAD - VCE

Smooth boarding, take off on time and landing ahead of schedule. Clean aircraft and nice crew.

Related info for your journey

  • What airports do I use to fly from Madrid to Santiago?

    To fly from Madrid to Santiago, you need to book a flight from Barajas (MAD) to Arturo Merino Benitez (SCL). Nonstop flights to Santiago Arturo Merino Benitez from Madrid Barajas take 13h 20m on average. When it comes time to book airfare, you have a few options: there are 10 outbound flights from Barajas to Arturo Merino Benitez offered by 1 airline.

  • How popular is this Madrid to Santiago flight route?

  • How long is the flight from Madrid to Santiago?

    A quick flight from Madrid to Santiago can take about 26h 20m. Delta provides one of the quickest options available for as low as £673. Airlines will cover a distance of 6656 mi.

  • What is the cheapest airline to fly from Madrid to Santiago round-trip?

    Cheapflights users have booked flights from Madrid to Santiago round-trip from £606. Users have found that Iberia is 27% cheaper than the other options available to this destination.

  • What are the most reliable airlines from Madrid to Santiago?

    No one likes to see their flight delayed. When booking a flight from Madrid to Santiago consider choosing Finnair (89%), EL AL (85%) or LATAM Airlines (80%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Madrid to Santiago?

    Looking at all options, your cheapest flight can be booked for £708. While the most popular route (Madrid Barajas - Santiago Arturo Merino Benitez) can be booked for £641 on average, our data indicates £902 when flying from Madrid to Santiago.

  • Can I find deals for flights from Madrid to Santiago that include hotel bookings?

    Yes. In addition to deals on Madrid to Santiago flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Madrid to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Madrid to Santiago.

  • Can I find deals for business class flights from Madrid to Santiago?

    Yes. Cheapflights offers flight deals from Madrid to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Madrid to Santiago?

    Currently, May is the cheapest month in which you can book a flight from Madrid to Santiago (average of £683). Flying from Madrid to Santiago in July is currently the most expensive (average of £1,099). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar

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Complete your trip

Top airline flying from Madrid to Santiago

AirlineCheapestAverageFlexibilityOn-time
IberiaCheapest£606Average£812FlexibilityNo cancel feeOn-time77%
Search Iberia flights

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