Cheap flights from Madrid, Spain to Santiago from £365
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 17/5. Fares are subject to change and may not be available on all flights or dates of travel.
MAD — SCL
17 Apr — 24 Apr1
Return
1 adult
Economy
Return
1 adult, Economy, 0 bags
Cheapflights Tip: The best prices from Madrid Barajas to Santiago Arturo Merino Benitez are usually found in March or May, booked 45 days in advance, depart on a Friday or Tuesday and return on a Wednesday
Cheap flight deals from Madrid to Santiago
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Cheapest flights from Madrid to Santiago
Explore the most affordable flight options available from Madrid to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 18 March 2026.
Fri 17/412:45
MAD
-
SCL
1 stop24h 30m
Delta
Mon 27/420:40
SCL
-
MAD
1 stop33h 35m
Delta
Deal found 15/3£637
Mon 2/1113:35
MAD
-
SCL
2 stops26h 40m
Air Canada
Fri 27/1108:25
SCL
-
MAD
1 stop19h 35m
Air Canada
Deal found 17/3£638
Wed 4/1110:00
MAD
-
SCL
2 stops25h 40m
Delta
Sun 22/1123:10
SCL
-
MAD
2 stops36h 10m
Delta
Deal found 13/3£640
Wed 4/1111:15
MAD
-
SCL
1 stop24h 25m
Delta
Wed 25/1123:10
SCL
-
MAD
1 stop30h 05m
Delta
Deal found 17/3£641
Fri 27/1111:55
MAD
-
SCL
2 stops26h 00m
Turkish Airlines
Wed 9/1211:40
SCL
-
MAD
2 stops24h 45m
Turkish Airlines
Deal found 17/3£641
Wed 15/412:45
MAD
-
SCL
1 stop24h 30m
Delta
Mon 27/420:40
SCL
-
MAD
1 stop33h 35m
Delta
Deal found 13/3£643
Mon 2/1113:35
MAD
-
SCL
2 stops26h 40m
Air Canada
Thu 26/1120:55
SCL
-
MAD
2 stops31h 05m
Air Canada
Deal found 17/3£644
Mon 27/412:45
MAD
-
SCL
1 stop24h 30m
Delta
Tue 12/520:40
SCL
-
MAD
2 stops27h 40m
Delta
Deal found 15/3£644
Tue 7/414:35
MAD
-
SCL
2 stops46h 40m
Delta
Fri 24/420:40
SCL
-
MAD
2 stops55h 15m
Delta
Deal found 16/3£645
Mon 9/1106:00
MAD
-
SCL
2 stops29h 40m
Delta
Sun 22/1123:10
SCL
-
MAD
2 stops40h 00m
Delta
Deal found 13/3£647
Mon 4/514:35
MAD
-
SCL
2 stops46h 40m
Delta
Tue 2/620:40
SCL
-
MAD
2 stops51h 40m
Delta
Deal found 14/3£647
Best flights from Madrid to Santiago
Discover carefully curated flight deals from Madrid to Santiago that have cost, travel time, and stopovers in mind to ensure you get the best travel experience. Data last updated 18 March 2026.
Tue 12/512:45
MAD
-
SCL
2 stops24h 30m
Delta
Thu 28/520:40
SCL
-
MAD
2 stops31h 15m
Delta
Deal found 17/3£692
Fri 1/518:25
MAD
-
SCL
2 stops44h 05m
Turkish Airlines
Mon 4/510:15
SCL
-
MAD
2 stops45h 20m
Turkish Airlines
Deal found 13/3£807
Tue 31/313:20
MAD
-
SCL
Nonstop13h 20m
Iberia
Tue 21/410:40
SCL
-
MAD
Nonstop12h 40m
Iberia
Deal found 13/3£811
Fri 10/411:05
MAD
-
SCL
1 stop18h 15m
Avianca
Sat 9/500:30
SCL
-
MAD
1 stop23h 40m
Avianca
Deal found 14/3£830
Thu 10/923:59
MAD
-
SCL
Nonstop13h 26m
Multiple Airlines
Sun 20/916:00
SCL
-
MAD
1 stop23h 35m
Multiple Airlines
Deal found 16/3£833
Fri 24/406:00
MAD
-
SCL
2 stops31h 15m
Delta
Sat 2/520:40
SCL
-
MAD
2 stops31h 15m
Delta
Deal found 13/3£713
Fri 17/412:45
MAD
-
SCL
1 stop24h 30m
Delta
Mon 20/420:40
SCL
-
MAD
2 stops31h 15m
Delta
Deal found 17/3£789
Tue 31/310:05
MAD
-
SCL
2 stops27h 10m
Delta
Tue 21/420:40
SCL
-
MAD
2 stops40h 55m
Delta
Deal found 16/3£816
Direct flights from Madrid to Santiago
Explore direct flight options from Madrid to Santiago based on user searches, and compare prices and availability for your desired travel dates. Data last updated 18 March 2026.
Sun 17/513:00
MAD
-
SCL
Nonstop13h 20m
Iberia
Tue 26/510:40
SCL
-
MAD
Nonstop12h 40m
Iberia
Deal found 16/3£649
Wed 13/513:20
MAD
-
SCL
Nonstop13h 20m
Iberia
Wed 27/522:20
SCL
-
MAD
Nonstop12h 40m
Iberia
Deal found 17/3£650
Sun 10/523:59
MAD
-
SCL
Nonstop13h 26m
Iberia
Wed 27/510:40
SCL
-
MAD
Nonstop12h 40m
Iberia
Deal found 17/3£652
Wed 6/513:20
MAD
-
SCL
Nonstop13h 20m
Iberia
Sun 24/522:00
SCL
-
MAD
Nonstop12h 40m
Iberia
Deal found 14/3£679
Thu 2/423:59
MAD
-
SCL
Nonstop13h 26m
Iberia
Mon 8/610:40
SCL
-
MAD
Nonstop12h 40m
Iberia
Deal found 17/3£680
Tue 12/513:15
MAD
-
SCL
Nonstop13h 20m
LATAM Airlines
Tue 26/519:00
SCL
-
MAD
Nonstop12h 55m
LATAM Airlines
Deal found 17/3£691
Mon 4/523:59
MAD
-
SCL
Nonstop13h 26m
Iberia
Sun 24/522:00
SCL
-
MAD
Nonstop12h 40m
Iberia
Deal found 14/3£707
Fri 15/513:20
MAD
-
SCL
Nonstop13h 20m
Iberia
Fri 29/522:20
SCL
-
MAD
Nonstop12h 40m
Iberia
Deal found 15/3£708
Wed 3/623:59
MAD
-
SCL
Nonstop13h 26m
Iberia
Wed 24/610:40
SCL
-
MAD
Nonstop12h 40m
Iberia
Deal found 15/3£732
Mon 1/613:20
MAD
-
SCL
Nonstop13h 20m
Iberia
Sun 14/622:00
SCL
-
MAD
Nonstop12h 40m
Iberia
Deal found 14/3£735
Fri 15/523:59
MAD
-
SCL
Nonstop13h 26m
Iberia
Wed 27/510:40
SCL
-
MAD
Nonstop12h 40m
Iberia
Deal found 17/3£749
Thu 30/423:59
MAD
-
SCL
Nonstop13h 26m
Iberia
Mon 18/510:40
SCL
-
MAD
Nonstop12h 40m
Iberia
Deal found 15/3£760
Last-minute flights from Madrid to Santiago
Discover last-minute flight deals from Madrid to Santiago. Data last updated 18 March 2026 and is based on user searches.
Mon 30/312:20
MAD
-
SCL
2 stops24h 55m
Delta
Mon 24/820:40
SCL
-
MAD
2 stops27h 40m
Delta
Deal found 14/3£665
Mon 6/410:05
MAD
-
SCL
2 stops27h 10m
Delta
Fri 24/420:40
SCL
-
MAD
2 stops55h 15m
Delta
Deal found 16/3£662
Tue 7/414:35
MAD
-
SCL
2 stops46h 40m
Delta
Fri 24/420:40
SCL
-
MAD
2 stops55h 15m
Delta
Deal found 16/3£645
Tue 7/412:45
MAD
-
SCL
1 stop24h 30m
Delta
Sat 25/420:40
SCL
-
MAD
2 stops31h 15m
Delta
Deal found 17/3£649
Wed 15/412:45
MAD
-
SCL
1 stop24h 30m
Delta
Mon 27/420:40
SCL
-
MAD
1 stop33h 35m
Delta
Deal found 13/3£643
Fri 17/412:45
MAD
-
SCL
1 stop24h 30m
Delta
Mon 27/420:40
SCL
-
MAD
1 stop33h 35m
Delta
Deal found 15/3£637
Tue 21/412:45
MAD
-
SCL
1 stop24h 30m
Delta
Mon 27/420:40
SCL
-
MAD
1 stop33h 35m
Delta
Deal found 17/3£641
Mon 27/412:45
MAD
-
SCL
1 stop24h 30m
Delta
Tue 12/520:40
SCL
-
MAD
2 stops27h 40m
Delta
Deal found 15/3£644
Mon 27/412:45
MAD
-
SCL
1 stop24h 30m
Delta
Fri 8/520:40
SCL
-
MAD
2 stops55h 15m
Delta
Deal found 13/3£651
Tue 28/412:45
MAD
-
SCL
1 stop24h 30m
Delta
Wed 3/620:40
SCL
-
MAD
2 stops27h 40m
Delta
Deal found 14/3£647
Tue 28/414:35
MAD
-
SCL
2 stops46h 40m
Delta
Sat 2/520:40
SCL
-
MAD
2 stops55h 15m
Delta
Deal found 13/3£660
One-way flights from Madrid to Santiago
Search for one-way flight options from Madrid to Santiago. Find affordable one-way fares based on user searches. Data last updated 18 March 2026.
Sun 17/513:00
MAD
-
SCL
Nonstop13h 20m
Iberia
Deal found 16/3£365
Tue 7/423:59
MAD
-
SCL
Nonstop13h 26m
Iberia
Deal found 18/3£368
Mon 23/323:35
MAD
-
SCL
Nonstop13h 15m
LATAM Airlines
Deal found 18/3£387
Tue 24/321:25
MAD
-
SCL
2 stops36h 05m
Multiple Airlines
Deal found 18/3£411
Mon 23/306:35
MAD
-
SCL
3 stops35h 36m
Multiple Airlines
Deal found 18/3£473
Sun 26/413:05
MAD
-
SCL
2 stops25h 40m
KLM
Deal found 15/3£482
Fri 1/513:05
MAD
-
SCL
2 stops25h 40m
KLM
Deal found 17/3£485
Fri 26/608:10
MAD
-
SCL
1 stop21h 10m
Avianca
Deal found 14/3£490
Wed 24/618:00
MAD
-
SCL
1 stop20h 45m
LEVEL
Deal found 16/3£496
Tue 23/617:20
MAD
-
SCL
1 stop26h 55m
Avianca
Deal found 13/3£523
Find flight deals from Madrid to Santiago
Discover tips and strategies to find the most affordable flight options for your journey from Madrid (MAD) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 18 March 2026.
Customise your flight search to find flights from Madrid to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 18 March 2026.
Use the filters below to find and compare flights from Madrid to Santiago that are best for you.
Fly from
Fly to
Route
Depart
Return
Price
Cheapest return flight
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Tue 12/5
12:45-07:15
2 stops24h 30m
Santiago Arturo Merino Benitez
Thu 28/5
20:40-09:55
2 stops31h 15m
£692
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Fri 24/4
06:00-07:15
2 stops31h 15m
Santiago Arturo Merino Benitez
Sat 2/5
20:40-09:55
2 stops31h 15m
£713
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Fri 17/4
12:45-07:15
1 stop24h 30m
Santiago Arturo Merino Benitez
Mon 20/4
20:40-09:55
2 stops31h 15m
£789
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Fri 1/5
18:25-08:30
2 stops44h 05m
Santiago Arturo Merino Benitez
Mon 4/5
10:15-13:35
2 stops45h 20m
£807
Fastest return journey
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Tue 31/3
13:20-21:40
Nonstop13h 20m
Santiago Arturo Merino Benitez
Tue 21/4
10:40-05:20
Nonstop12h 40m
£811
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Tue 31/3
10:05-08:15
2 stops27h 10m
Santiago Arturo Merino Benitez
Tue 21/4
20:40-19:35
2 stops40h 55m
£816
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Fri 10/4
11:05-23:20
1 stop18h 15m
Santiago Arturo Merino Benitez
Sat 9/5
00:30-06:10
1 stop23h 40m
£830
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Thu 10/9
23:59-08:25
Nonstop13h 26m
Santiago Arturo Merino Benitez
Sun 20/9
16:00-20:35
1 stop23h 35m
£833
Cheapest one-way
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Tue 7/4
23:59-07:25
Nonstop13h 26m
£368
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Fri 1/5
13:05-08:45
2 stops25h 40m
£485
Flights are sorted by cheapest return flights first.
Deals found on 18/3
Showing 1-10 of 16 resultsSorted by cheapest first
1
2
Best time to book a flight from Madrid to Santiago
Have a flexible travel schedule? Discover the best time to fly to Santiago from Madrid with our price prediction graph.
MAD-SCL
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Madrid to Santiago
Prices
Airlines
Delays
How far ahead should I book a flight from Madrid to Santiago?
Use this chart to determine the optimal time to book a return flight from Madrid to Santiago. Price data was last updated on 13 March 2026.
The price you pay for your flight from Madrid to Santiago may vary depending on when you book. For the best chance of a lower fare, look to book 45 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Madrid to Santiago?
Currently, March is the cheapest month in which you can book a flight from Madrid to Santiago (average of £378). Flying from Madrid to Santiago in July is currently the most expensive (average of £809). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MAD to SCL?
Find hourly flight availability from Madrid to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 18 March 2026.
When flying from Madrid to Santiago, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
Weekly flight availability from Madrid to Santiago
Explore weekly flight availability from Madrid to Santiago. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated 18 March 2026.
The most flights from MAD to SCL are scheduled on a Monday (17 on average). You will have fewer flight options on Thursday, which is when the least amount of flights are scheduled (7 on average).
How often are flights from Madrid to Santiago delayed?
About 14% of weekly flights between Madrid and Santiago have experienced delays in the past year, with the average delay time being 133 minutes.
What is the most punctual flight time for Madrid to Santiago flights?
Historically, flights departing at night are less likely to be delayed, whereas flights leaving in the early afternoon tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Saturday tends to have the lowest number of delays on this route, whereas Sunday has historically faced a higher average of delays compared to other days of the week.
Which airline has the best punctuality record on Madrid to Santiago flights?
Over the past year, LATAM Airlines have had the lowest number of delays on this route, with just 11% of flights being delayed.
Reviews of airlines servicing Santiago
Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated 18 March 2026.
Read through reviews of airlines operating flights from Madrid to Santiago, such as LATAM Airlines and Iberia. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Plane was late in FLN and missed connection in GRU. No alternative was given to me until 6 hours later and I was delayed by over 12 hours total.
Related info for your journey
Find useful and relevant information for your journey from Madrid to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
What airports do I use to fly from Madrid to Santiago?
To fly from Madrid to Santiago, you need to book a flight from Barajas (MAD) to Arturo Merino Benitez (SCL). Nonstop flights to Santiago Arturo Merino Benitez from Madrid Barajas take 13h 20m on average. When it comes time to book airfare, you have a few options: there are 13 outbound flights from Barajas to Arturo Merino Benitez offered by 2 different airlines.
How popular is this Madrid to Santiago flight route?
This flight path from Madrid Barajas to Santiago Arturo Merino Benitez was viewed by 16 users in the past month. Keep an eye out for changes in search interest prior to high and low season.
How long is the flight from Madrid to Santiago?
A quick flight from Madrid to Santiago can take about 24h 30m. Delta provides one of the quickest options available for as low as £692. Airlines will cover a distance of 6656 mi. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.
What are the cheapest airlines flying from Madrid to Santiago round-trip?
Cheapflights users have booked flights from Madrid to Santiago round-trip from £644. Another airline that can offer you cheap pricing is LATAM Airlines. Users have found that Iberia is 23% cheaper than the other options available to this destination.
What are the most reliable airlines from Madrid to Santiago?
No one likes to see their flight delayed. When booking a flight from Madrid to Santiago consider choosing Japan Airlines (83%), EL AL (83%) or Finnair (82%) as they are the most reliable in getting you off to your destination on time.
What are the cheapest flights from Madrid to Santiago?
Looking at all options, your cheapest flight can be booked for £477. While the most popular route (Madrid Barajas - Santiago Arturo Merino Benitez) can be booked for £605 on average, our data indicates £782 when flying from Madrid to Santiago.
Can I find deals for business class flights from Madrid to Santiago?
Yes. Cheapflights offers flight deals from Madrid to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Madrid to Santiago?
Currently, March is the cheapest month in which you can book a flight from Madrid to Santiago (average of £378). Flying from Madrid to Santiago in July is currently the most expensive (average of £809). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Explore flights to Santiago departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on 18 March 2026.
Discover the top 2 airlines that operate flights from Madrid to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 18 March 2026.
Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.
How does Cheapflights help users find flights from Madrid to Santiago?
Cheapflights makes it easy to find Madrid to Santiago flights by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.
Why should you use Cheapflights to find cheap flight tickets from Madrid to Santiago?
Millions of users choose and trust Cheapflights to book the best flight deals from Madrid to Santiago for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.
Can Cheapflights find flights from Madrid to Santiago with no change fees?
Certainly. Search results for flights to Santiago from Madrid shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.
Can Cheapflights notify me if prices for flights from Madrid to Santiago become cheaper?
Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!
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