Cheap flights from Madrid, Spain to Santiago from £426
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 16/3. Fares are subject to change and may not be available on all flights or dates of travel.
MAD — SCL
1 Jan — 8 Jan1
Return
1 adult
Economy
Return
1 adult, Economy, 0 bags
Cheapflights Tip: The best prices from Madrid Barajas to Santiago Arturo Merino Benitez are usually found in March or February, booked 68 days in advance, depart on a Thursday or Tuesday and return on a Wednesday
Find flight deals from Madrid to Santiago
Enter your travel dates to find the best prices.
Cheapest flights from Madrid to Santiago
Explore the most affordable flight options available from Madrid to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 2 December 2025.
Thu 4/1211:15MAD - SCL
1 stop24h 25mDelta
Sun 1/223:10SCL - MAD
2 stops28h 50mDelta
Deal found 29/11£614
Wed 3/1211:15MAD - SCL
1 stop22h 55mDelta
Tue 9/1223:10SCL - MAD
1 stop30h 05mDelta
Deal found 1/12£615
Sun 7/1211:15MAD - SCL
1 stop22h 55mDelta
Tue 20/123:10SCL - MAD
2 stops28h 50mDelta
Deal found 29/11£658
Sun 7/1206:00MAD - SCL
2 stops29h 40mDelta
Tue 10/223:10SCL - MAD
2 stops31h 05mDelta
Deal found 1/12£664
Thu 4/1211:15MAD - SCL
1 stop24h 25mDelta
Mon 8/1221:30SCL - MAD
2 stops30h 30mDelta
Deal found 30/11£667
Sun 7/1211:15MAD - SCL
1 stop22h 55mDelta
Mon 19/121:30SCL - MAD
2 stops32h 45mDelta
Deal found 29/11£691
Sun 7/1211:15MAD - SCL
1 stop24h 25mDelta
Sun 8/322:10SCL - MAD
1 stop29h 55mDelta
Deal found 28/11£693
Best flights from Madrid to Santiago
Discover carefully curated flight deals from Madrid to Santiago that have cost, travel time, and stopovers in mind to ensure you get the best travel experience. Data last updated 2 December 2025.
Mon 19/110:00MAD - SCL
2 stops25h 40mDelta
Thu 19/223:10SCL - MAD
1 stop30h 05mDelta
Deal found 29/11£614
Sat 24/111:15MAD - SCL
2 stops49h 35mUnited Airlines
Wed 28/122:45SCL - MAD
2 stops30h 30mUnited Airlines
Deal found 29/11£650
Wed 14/110:00MAD - SCL
2 stops25h 40mDelta
Wed 25/223:10SCL - MAD
2 stops28h 50mDelta
Deal found 29/11£614
Mon 18/510:05MAD - SCL
1 stop26h 55mDelta
Mon 1/620:40SCL - MAD
2 stops29h 10mDelta
Deal found 1/12£615
Mon 2/310:00MAD - SCL
2 stops25h 40mDelta
Sun 22/322:10SCL - MAD
2 stops32h 05mDelta
Deal found 30/11£646
Sat 17/111:15MAD - SCL
1 stop24h 25mDelta
Tue 10/223:10SCL - MAD
2 stops36h 55mDelta
Deal found 30/11£646
Sat 24/110:00MAD - SCL
2 stops48h 10mDelta
Tue 10/223:10SCL - MAD
2 stops36h 55mDelta
Deal found 30/11£646
Sun 8/306:00MAD - SCL
2 stops29h 40mDelta
Sun 22/322:10SCL - MAD
2 stops37h 10mDelta
Deal found 30/11£647
Thu 21/510:05MAD - SCL
1 stop26h 55mDelta
Mon 1/620:40SCL - MAD
2 stops29h 10mDelta
Deal found 1/12£658
Thu 21/510:05MAD - SCL
1 stop26h 55mDelta
Fri 5/620:40SCL - MAD
2 stops53h 10mDelta
Deal found 1/12£658
Mon 18/512:40MAD - SCL
2 stops48h 20mDelta
Fri 5/620:40SCL - MAD
2 stops53h 10mDelta
Deal found 1/12£658
Direct flights from Madrid to Santiago
Explore direct flight options from Madrid to Santiago based on user searches, and compare prices and availability for your desired travel dates. Data last updated 2 December 2025.
Thu 12/323:35MAD - SCL
Nonstop13h 15mLATAM Airlines
Sun 22/313:05SCL - MAD
Nonstop12h 35mLATAM Airlines
Deal found 30/11£638
Wed 4/223:35MAD - SCL
Nonstop13h 15mLATAM Airlines
Wed 25/221:00SCL - MAD
Nonstop13h 00mLATAM Airlines
Deal found 29/11£639
Sun 15/312:55MAD - SCL
Nonstop13h 20mIberia
Sun 29/311:40SCL - MAD
Nonstop12h 40mIberia
Deal found 29/11£652
Tue 31/313:20MAD - SCL
Nonstop13h 20mIberia
Tue 21/410:40SCL - MAD
Nonstop12h 40mIberia
Deal found 29/11£653
Tue 19/513:10MAD - SCL
Nonstop13h 20mLATAM Airlines
Wed 3/619:00SCL - MAD
Nonstop12h 55mLATAM Airlines
Deal found 1/12£654
Thu 21/513:10MAD - SCL
Nonstop13h 20mLATAM Airlines
Thu 4/616:00SCL - MAD
Nonstop12h 55mLATAM Airlines
Deal found 1/12£660
Mon 6/423:59MAD - SCL
Nonstop13h 26mIberia
Sun 19/422:00SCL - MAD
Nonstop12h 40mIberia
Deal found 30/11£685
Tue 19/513:20MAD - SCL
Nonstop13h 20mIberia
Fri 5/610:40SCL - MAD
Nonstop12h 40mIberia
Deal found 1/12£698
Fri 22/513:20MAD - SCL
Nonstop13h 20mIberia
Fri 5/622:20SCL - MAD
Nonstop12h 40mIberia
Deal found 1/12£724
Sat 23/513:10MAD - SCL
Nonstop13h 20mLATAM Airlines
Thu 4/616:00SCL - MAD
Nonstop12h 55mLATAM Airlines
Deal found 1/12£731
Fri 13/312:55MAD - SCL
Nonstop13h 20mIberia
Mon 13/410:40SCL - MAD
Nonstop12h 40mIberia
Deal found 29/11£774
Tue 17/312:55MAD - SCL
Nonstop13h 20mIberia
Mon 6/410:40SCL - MAD
Nonstop12h 40mIberia
Deal found 30/11£786
Last-minute flights from Madrid to Santiago
Discover last-minute flight deals from Madrid to Santiago. Data last updated 2 December 2025 and is based on user searches.
Wed 3/1211:15MAD - SCL
1 stop22h 55mDelta
Tue 9/1223:10SCL - MAD
2 stops28h 50mDelta
Deal found 30/11£615
Thu 15/106:00MAD - SCL
2 stops29h 40mDelta
Sun 1/223:10SCL - MAD
2 stops28h 50mDelta
Deal found 29/11£640
Thu 15/106:00MAD - SCL
2 stops28h 10mDelta
Tue 3/223:10SCL - MAD
1 stop30h 05mDelta
Deal found 30/11£641
Sat 17/111:15MAD - SCL
1 stop22h 55mDelta
Thu 19/223:10SCL - MAD
2 stops28h 50mDelta
Deal found 29/11£614
Sat 17/110:00MAD - SCL
2 stops25h 40mDelta
Sun 8/322:10SCL - MAD
2 stops28h 50mDelta
Deal found 29/11£615
Sat 17/111:15MAD - SCL
1 stop22h 55mDelta
Mon 9/223:10SCL - MAD
2 stops34h 10mDelta
Deal found 1/12£626
Sat 17/110:00MAD - SCL
2 stops25h 40mDelta
Fri 6/223:10SCL - MAD
2 stops40h 00mDelta
Deal found 29/11£628
Sat 17/110:00MAD - SCL
2 stops25h 40mDelta
Tue 3/323:10SCL - MAD
2 stops40h 00mDelta
Deal found 29/11£629
Sat 17/106:00MAD - SCL
2 stops29h 40mDelta
Mon 26/121:30SCL - MAD
2 stops30h 30mDelta
Deal found 1/12£633
Sat 17/110:00MAD - SCL
2 stops25h 40mDelta
Mon 2/223:10SCL - MAD
2 stops33h 00mDelta
Deal found 29/11£645
Thu 22/113:35MAD - SCL
1 stop21h 15mMultiple Airlines
Tue 10/204:35SCL - MAD
2 stops23h 25mMultiple Airlines
Deal found 30/11£618
Thu 29/106:00MAD - SCL
2 stops29h 40mDelta
Fri 6/323:10SCL - MAD
2 stops51h 50mDelta
Deal found 28/11£633
One-way flights from Madrid to Santiago
Search for one-way flight options from Madrid to Santiago. Find affordable one-way fares based on user searches. Data last updated 2 December 2025.
Mon 19/116:20MAD - SCL
1 stop27h 00mAvianca
Deal found 29/11£426
Fri 10/401:30MAD - SCL
1 stop17h 55mAvianca
Deal found 30/11£427
Wed 25/206:30MAD - SCL
3 stops36h 55mMultiple Airlines
Deal found 30/11£429
Sun 8/312:55MAD - SCL
Nonstop13h 20mIberia
Deal found 30/11£437
Mon 8/1211:05MAD - SCL
2 stops49h 45mUnited Airlines
Deal found 30/11£438
Thu 29/111:15MAD - SCL
2 stops49h 35mUnited Airlines
Deal found 30/11£442
Sat 6/1218:00MAD - SCL
2 stops33h 35mMultiple Airlines
Deal found 1/12£450
Sat 6/1211:50MAD - SCL
1 stop27h 50mLATAM Airlines
Deal found 1/12£509
Mon 16/306:40MAD - SCL
2 stops26h 50mAvianca
Deal found 29/11£511
Cheap flight deals from Madrid to Santiago
Discover tips and strategies to find the most affordable flight options for your journey from Madrid (MAD) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 2 December 2025.
Customise your flight search to find flights from Madrid to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 2 December 2025.
Use the filters below to find and compare flights from Madrid to Santiago that are best for you.
Fly from
Madrid
Fly to
Santiago
Route
Depart
Return
Price
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Mon 19/1
10:00-07:40
2 stops25h 40m
Santiago Arturo Merino Benitez
Thu 19/2
23:10-09:15
1 stop30h 05m
£614
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Wed 14/1
10:00-07:40
2 stops25h 40m
Santiago Arturo Merino Benitez
Wed 25/2
23:10-08:00
2 stops28h 50m
£614
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Mon 18/5
10:05-07:00
1 stop26h 55m
Santiago Arturo Merino Benitez
Mon 1/6
20:40-07:50
2 stops29h 10m
£615
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Mon 2/3
10:00-07:40
2 stops25h 40m
Santiago Arturo Merino Benitez
Sun 22/3
22:10-10:15
2 stops32h 05m
£646
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Sat 17/1
11:15-07:40
1 stop24h 25m
Santiago Arturo Merino Benitez
Tue 10/2
23:10-16:05
2 stops36h 55m
£646
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Sat 24/1
10:00-06:10
2 stops48h 10m
Santiago Arturo Merino Benitez
Tue 10/2
23:10-16:05
2 stops36h 55m
£646
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Sun 8/3
06:00-07:40
2 stops29h 40m
Santiago Arturo Merino Benitez
Sun 22/3
22:10-15:20
2 stops37h 10m
£647
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Sat 24/1
11:15-08:50
2 stops49h 35m
Santiago Arturo Merino Benitez
Wed 28/1
22:45-09:15
2 stops30h 30m
£650
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Thu 21/5
10:05-07:00
1 stop26h 55m
Santiago Arturo Merino Benitez
Mon 1/6
20:40-07:50
2 stops29h 10m
£658
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Thu 21/5
10:05-07:00
1 stop26h 55m
Santiago Arturo Merino Benitez
Fri 5/6
20:40-07:50
2 stops53h 10m
£658
Flights are sorted by cheapest return flights first.
Deals found on 29/11
Showing 1-10 of 21 results
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Best time to book a flight from Madrid to Santiago
Have a flexible travel schedule? Discover the best time to fly to Santiago from Madrid with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Madrid to Santiago
Prices
Airlines
Delays
How far ahead should I book a flight from Madrid to Santiago?
Use this chart to determine the optimal time to book a return flight from Madrid to Santiago. Price data was last updated on 28 November 2025.
The price you pay for your flight from Madrid to Santiago may vary depending on when you book. For the best chance of a lower fare, look to book 68 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Madrid to Santiago?
Currently, March is the cheapest month in which you can book a flight from Madrid to Santiago (average of £383). Flying from Madrid to Santiago in July is currently the most expensive (average of £675). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MAD to SCL?
Find hourly flight availability from Madrid to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 2 December 2025.
A simple way to save on the total cost of your ticket is to fly from Madrid to Santiago in the morning. If you’re flexible enough to do this you can expect to save up to 11% on your trip compared to booking a flight in the afternoon.
Weekly flight availability from Madrid to Santiago
Explore weekly flight availability from Madrid to Santiago. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated 2 December 2025.
The most flights from MAD to SCL are scheduled on a Monday (17 on average). You will have fewer flight options on Thursday, which is when the least amount of flights are scheduled (9 on average).
How often are flights from Madrid to Santiago delayed?
About 11% of weekly flights between Madrid and Santiago have experienced delays in the past year, with the average delay time being 132 minutes.
What is the most punctual flight time for Madrid to Santiago flights?
Historically, flights departing in the evening are less likely to be delayed, whereas flights leaving in the early afternoon tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Thursday tends to have the lowest number of delays on this route, whereas Friday has historically faced a higher average of delays compared to other days of the week.
Which airline has the best punctuality record on Madrid to Santiago flights?
Over the past year, LATAM Airlines have had the lowest number of delays on this route, with just 8% of flights being delayed.
Reviews of airlines servicing Santiago
Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated 2 December 2025.
Read through reviews of airlines operating flights from Madrid to Santiago, such as LATAM Airlines, Iberia, andBritish Airways. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Terrible baggage service! Almost lost my connection flight in SP
Related info for your journey
Find useful and relevant information for your journey from Madrid to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
What airports do I use to fly from Madrid to Santiago?
To fly from Madrid to Santiago, you need to book a flight from Barajas (MAD) to Arturo Merino Benitez (SCL). Nonstop flights to Santiago Arturo Merino Benitez from Madrid Barajas take 13h 15m on average. When it comes time to book airfare, you have a few options: there are 14 outbound flights from Barajas to Arturo Merino Benitez offered by 3 different airlines.
How popular is this Madrid to Santiago flight route?
This flight path from Madrid Barajas to Santiago Arturo Merino Benitez was viewed by 14 users in the past month. Keep an eye out for changes in search interest prior to high and low season.
How long is the flight from Madrid to Santiago?
A quick flight from Madrid to Santiago can take about 25h 40m. Delta provides one of the quickest options available for as low as £614. Airlines will cover a distance of 6656 mi.
What are the cheapest airlines flying from Madrid to Santiago round-trip?
Cheapflights users have booked flights from Madrid to Santiago round-trip from £523. Other airlines that can offer you cheap pricing are Iberia, from £639, and LATAM Airlines, from £641. Users have found that British Airways is 36% cheaper than the other options available to this destination.
What are the cheapest airlines to fly from Madrid to Santiago one-way?
To fly one-way, consider booking your trip with Avianca, which is currently one of the cheapest options available, starting at £426. United Airlines flights start at £437 while deals on Iberia start at £437 one-way.
What are the most reliable airlines from Madrid to Santiago?
No one likes to see their flight delayed. When booking a flight from Madrid to Santiago consider choosing Japan Airlines (80%), EL AL (80%) or Finnair (80%) as they are the most reliable in getting you off to your destination on time.
What are the cheapest flights from Madrid to Santiago?
Looking at all options, your cheapest flight can be booked for £459. While the most popular route (Madrid Barajas - Santiago Arturo Merino Benitez) can be booked for £497 on average, our data indicates £772 when flying from Madrid to Santiago.
Can I find deals for business class flights from Madrid to Santiago?
Yes. Cheapflights offers flight deals from Madrid to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Madrid to Santiago?
Currently, March is the cheapest month in which you can book a flight from Madrid to Santiago (average of £383). Flying from Madrid to Santiago in July is currently the most expensive (average of £675). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Explore flights to Santiago departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on 2 December 2025.
Discover the top 3 airlines that operate flights from Madrid to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 2 December 2025.
Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.
How does Cheapflights help users find flights from Madrid to Santiago?
Cheapflights makes it easy to find Madrid to Santiago flights by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.
Why should you use Cheapflights to find cheap flight tickets from Madrid to Santiago?
Millions of users choose and trust Cheapflights to book the best flight deals from Madrid to Santiago for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.
Can Cheapflights find flights from Madrid to Santiago with no change fees?
Certainly. Search results for flights to Santiago from Madrid shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.
Can Cheapflights notify me if prices for flights from Madrid to Santiago become cheaper?
Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!
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