Cheap flights from Madrid, Spain to Santiago from £363
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 19/11. Fares are subject to change and may not be available on all flights or dates of travel.
MAD — SCL
16 Oct — 23 Oct1
Return
1 adult
Economy
Return
1 adult, Economy
Cheapflights Tip: The best prices from Madrid Barajas to Santiago Arturo Merino Benitez are usually found in March or April, booked 88 days in advance, depart on a Wednesday or Thursday and return on a Wednesday
Cheap flight deals from Madrid to Santiago
Discover tips and strategies to find the most affordable flight options for your journey from Madrid (MAD) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 16 September 2025.
Explore the most affordable flight options available from Madrid to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 16 September 2025.
Mon 15/910:05MAD - SCL
2 stops25h 55mDelta
Mon 22/921:40SCL - MAD
2 stops32h 40mDelta
Deal found 14/9£637
Mon 3/1111:15MAD - SCL
1 stop24h 25mDelta
Mon 17/1123:10SCL - MAD
1 stop30h 05mDelta
Deal found 15/9£638
Wed 26/1111:05MAD - SCL
2 stops49h 45mUnited Airlines
Sun 15/321:45SCL - MAD
2 stops54h 20mUnited Airlines
Deal found 16/9£639
Tue 16/911:45MAD - SCL
1 stop28h 45mBritish Airways
Tue 28/1013:05SCL - MAD
1 stop18h 50mBritish Airways
Deal found 15/9£641
Mon 10/1106:00MAD - SCL
2 stops29h 40mDelta
Sun 23/1123:10SCL - MAD
2 stops32h 20mDelta
Deal found 15/9£644
Wed 31/1210:00MAD - SCL
2 stops48h 10mDelta
Mon 2/223:15SCL - MAD
2 stops52h 45mDelta
Deal found 15/9£648
Wed 10/1211:15MAD - SCL
1 stop24h 25mDelta
Wed 21/123:15SCL - MAD
2 stops28h 45mDelta
Deal found 16/9£648
Tue 16/906:00MAD - SCL
2 stops30h 00mDelta
Tue 28/1022:10SCL - MAD
2 stops32h 05mDelta
Deal found 15/9£653
Mon 24/1111:15MAD - SCL
1 stop24h 25mDelta
Wed 26/1123:10SCL - MAD
2 stops28h 50mDelta
Deal found 15/9£656
Mon 10/1106:00MAD - SCL
2 stops29h 40mDelta
Mon 24/1123:10SCL - MAD
2 stops40h 30mDelta
Deal found 15/9£659
Fri 5/1206:00MAD - SCL
2 stops29h 40mDelta
Mon 9/323:15SCL - MAD
2 stops32h 55mDelta
Deal found 16/9£660
Tue 4/1110:00MAD - SCL
2 stops25h 40mDelta
Tue 18/1123:10SCL - MAD
2 stops32h 20mDelta
Deal found 15/9£662
Best flights from Madrid to Santiago
Discover carefully curated flight deals from Madrid to Santiago that have cost, travel time, and stopovers in mind to ensure you get the best travel experience. Data last updated 16 September 2025.
Thu 29/111:15MAD - SCL
2 stops49h 35mUnited Airlines
Fri 6/322:45SCL - MAD
2 stops53h 20mUnited Airlines
Deal found 14/9£639
Mon 3/1106:00MAD - SCL
2 stops29h 40mDelta
Sun 23/1123:10SCL - MAD
2 stops36h 10mDelta
Deal found 14/9£644
Wed 29/1010:05MAD - SCL
1 stop25h 35mDelta
Wed 5/1123:10SCL - MAD
2 stops28h 50mDelta
Deal found 14/9£648
Mon 29/1210:00MAD - SCL
2 stops48h 10mDelta
Thu 15/123:15SCL - MAD
2 stops28h 45mDelta
Deal found 15/9£648
Mon 8/1211:15MAD - SCL
1 stop24h 25mDelta
Sat 24/121:30SCL - MAD
2 stops30h 30mDelta
Deal found 15/9£648
Mon 29/1210:00MAD - SCL
2 stops48h 10mDelta
Sun 18/123:15SCL - MAD
1 stop29h 45mDelta
Deal found 15/9£648
Tue 9/1210:00MAD - SCL
2 stops25h 40mDelta
Sat 24/121:30SCL - MAD
2 stops30h 30mDelta
Deal found 15/9£648
Tue 4/1111:15MAD - SCL
1 stop24h 25mDelta
Tue 18/1123:10SCL - MAD
2 stops32h 20mDelta
Deal found 15/9£662
Sun 16/1111:15MAD - SCL
1 stop24h 25mDelta
Sun 30/1123:10SCL - MAD
2 stops33h 00mDelta
Deal found 15/9£680
Sun 9/1106:00MAD - SCL
2 stops29h 40mDelta
Sun 23/1123:10SCL - MAD
2 stops36h 10mDelta
Deal found 15/9£689
Wed 31/1210:00MAD - SCL
2 stops48h 10mDelta
Thu 15/123:15SCL - MAD
2 stops28h 45mDelta
Deal found 15/9£691
Direct flights from Madrid to Santiago
Explore direct flight options from Madrid to Santiago based on user searches, and compare prices and availability for your desired travel dates. Data last updated 16 September 2025.
Fri 6/323:59MAD - SCL
Nonstop13h 21mIberia
Sun 15/323:55SCL - MAD
Nonstop12h 40mIberia
Deal found 15/9£643
Thu 4/1223:59MAD - SCL
Nonstop13h 21mIberia
Sun 1/213:05SCL - MAD
Nonstop12h 35mIberia
Deal found 14/9£713
Wed 29/1012:55MAD - SCL
Nonstop13h 20mIberia
Wed 5/1123:55SCL - MAD
Nonstop12h 40mIberia
Deal found 14/9£795
Thu 13/1123:35MAD - SCL
Nonstop13h 15mLATAM Airlines
Sun 16/1121:00SCL - MAD
Nonstop13h 00mLATAM Airlines
Deal found 14/9£977
Wed 12/1123:59MAD - SCL
Nonstop13h 21mIberia
Mon 17/1113:05SCL - MAD
Nonstop12h 35mIberia
Deal found 15/9£994
Sat 27/913:25MAD - SCL
Nonstop13h 25mLATAM Airlines
Sat 4/1020:00SCL - MAD
Nonstop12h 55mLATAM Airlines
Deal found 15/9£1,077
Sat 27/923:59MAD - SCL
Nonstop13h 25mIberia
Sat 4/1011:55SCL - MAD
Nonstop12h 40mIberia
Deal found 14/9£1,118
Tue 7/1013:25MAD - SCL
Nonstop13h 25mLATAM Airlines
Fri 31/1021:00SCL - MAD
Nonstop13h 00mLATAM Airlines
Deal found 14/9£3,933
Wed 7/123:59MAD - SCL
Nonstop13h 21mIberia
Sun 18/123:55SCL - MAD
Nonstop12h 40mIberia
Deal found 15/9£4,047
Fri 26/913:20MAD - SCL
Nonstop13h 15mIberia
Sat 4/1011:55SCL - MAD
Nonstop12h 40mIberia
Deal found 14/9£4,685
Last-minute flights from Madrid to Santiago
Discover last-minute flight deals from Madrid to Santiago. Data last updated 16 September 2025 and is based on user searches.
Mon 15/910:05MAD - SCL
2 stops25h 55mDelta
Mon 22/921:40SCL - MAD
2 stops32h 40mDelta
Deal found 14/9£637
Tue 16/911:45MAD - SCL
1 stop28h 45mBritish Airways
Tue 28/1013:05SCL - MAD
1 stop18h 50mBritish Airways
Deal found 15/9£641
Tue 16/906:00MAD - SCL
2 stops30h 00mDelta
Tue 28/1022:10SCL - MAD
2 stops32h 05mDelta
Deal found 15/9£653
Mon 22/912:40MAD - SCL
2 stops47h 20mDelta
Sun 28/921:40SCL - MAD
1 stop30h 55mDelta
Deal found 14/9£648
Tue 23/912:40MAD - SCL
2 stops47h 20mDelta
Sun 28/921:40SCL - MAD
1 stop30h 55mDelta
Deal found 14/9£656
Tue 14/1006:00MAD - SCL
2 stops30h 00mDelta
Wed 5/1123:10SCL - MAD
1 stop30h 05mDelta
Deal found 14/9£665
Thu 23/1006:00MAD - SCL
2 stops30h 00mDelta
Thu 6/1123:10SCL - MAD
2 stops28h 50mDelta
Deal found 15/9£666
Wed 29/1010:05MAD - SCL
1 stop25h 35mDelta
Tue 25/1123:10SCL - MAD
2 stops40h 00mDelta
Deal found 14/9£662
Thu 30/1006:00MAD - SCL
2 stops29h 40mDelta
Thu 6/1123:10SCL - MAD
1 stop30h 05mDelta
Deal found 15/9£664
Fri 31/1006:00MAD - SCL
2 stops29h 40mDelta
Wed 12/1123:10SCL - MAD
2 stops36h 10mDelta
Deal found 15/9£644
Fri 31/1006:00MAD - SCL
2 stops29h 40mDelta
Fri 7/1123:10SCL - MAD
1 stop30h 05mDelta
Deal found 16/9£664
One-way flights from Madrid to Santiago
Search for one-way flight options from Madrid to Santiago. Find affordable one-way fares based on user searches. Data last updated 16 September 2025.
Wed 19/1105:55MAD - SCL
2 stops30h 55mUnited Airlines
Deal found 14/9£363
Mon 10/1101:20MAD - SCL
1 stop27h 10mAvianca
Deal found 15/9£420
Wed 5/1116:20MAD - SCL
1 stop27h 00mAvianca
Deal found 15/9£421
Thu 6/1111:15MAD - SCL
2 stops25h 35mUnited Airlines
Deal found 15/9£430
Fri 24/1011:15MAD - SCL
2 stops49h 35mUnited Airlines
Deal found 14/9£435
Tue 2/1216:20MAD - SCL
1 stop27h 00mAvianca
Deal found 15/9£436
Wed 1/1006:55MAD - SCL
3 stops49h 40mMultiple Airlines
Deal found 14/9£447
Fri 7/1116:20MAD - SCL
1 stop36h 10mAvianca
Deal found 15/9£451
Sun 8/312:55MAD - SCL
Nonstop13h 20mIberia
Deal found 14/9£464
Tue 30/901:30MAD - SCL
1 stop17h 55mAvianca
Deal found 14/9£473
Cheapflights Fare Finder
Customise your flight search to find flights from Madrid to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 16 September 2025.
Use the filters below to find and compare flights from Madrid to Santiago that are best for you.
Fly from
Madrid
Fly to
Santiago
Route
Depart
Return
Price
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Thu 29/1
11:15-08:50
2 stops49h 35m
Santiago Arturo Merino Benitez
Fri 6/3
22:45-08:05
2 stops53h 20m
£639
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Mon 3/11
06:00-07:40
2 stops29h 40m
Santiago Arturo Merino Benitez
Sun 23/11
23:10-15:20
2 stops36h 10m
£644
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Wed 29/10
10:05-07:40
1 stop25h 35m
Santiago Arturo Merino Benitez
Wed 5/11
23:10-08:00
2 stops28h 50m
£648
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Mon 29/12
10:00-06:10
2 stops48h 10m
Santiago Arturo Merino Benitez
Thu 15/1
23:15-08:00
2 stops28h 45m
£648
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Mon 8/12
11:15-07:40
1 stop24h 25m
Santiago Arturo Merino Benitez
Sat 24/1
21:30-08:00
2 stops30h 30m
£648
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Mon 29/12
10:00-06:10
2 stops48h 10m
Santiago Arturo Merino Benitez
Sun 18/1
23:15-09:00
1 stop29h 45m
£648
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Tue 9/12
10:00-07:40
2 stops25h 40m
Santiago Arturo Merino Benitez
Sat 24/1
21:30-08:00
2 stops30h 30m
£648
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Tue 4/11
11:15-07:40
1 stop24h 25m
Santiago Arturo Merino Benitez
Tue 18/11
23:10-11:30
2 stops32h 20m
£662
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Sun 16/11
11:15-07:40
1 stop24h 25m
Santiago Arturo Merino Benitez
Sun 30/11
23:10-12:10
2 stops33h 00m
£680
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Sun 9/11
06:00-07:40
2 stops29h 40m
Santiago Arturo Merino Benitez
Sun 23/11
23:10-15:20
2 stops36h 10m
£689
Flights are sorted by cheapest return flights first.
Deals found on 14/9
Showing 1-10 of 20 results
1
2
Best time to book a flight from Madrid to Santiago
Have a flexible travel schedule? Discover the best time to fly to Santiago from Madrid with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Madrid to Santiago
Prices
Airlines
More
How far ahead should I book a flight from Madrid to Santiago?
Use this chart to determine the optimal time to book a return flight from Madrid to Santiago. Price data was last updated on 12 September 2025.
The price you pay for your flight from Madrid to Santiago may vary depending on when you book. For the best chance of a lower fare, look to book 88 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Madrid to Santiago?
Currently, May is the cheapest month in which you can book a flight from Madrid to Santiago (average of £1,031). Flying from Madrid to Santiago in December is currently the most expensive (average of £1,468). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MAD to SCL?
Find hourly flight availability from Madrid to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 16 September 2025.
A simple way to save on the total cost of your ticket is to fly from Madrid to Santiago in the afternoon. If you’re flexible enough to do this you can expect to save up to 15% on your trip compared to booking a flight at midday.
How much does it cost for a return flight from Madrid to Santiago?
Weekly flight availability from Madrid to Santiago
Explore weekly flight availability from Madrid to Santiago. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated 16 September 2025.
The most flights from MAD to SCL are scheduled on a Friday (19 on average). You will have fewer flight options on Wednesday, which is when the least amount of flights are scheduled (12 on average).
What’s the top stopover airport for flights from Madrid to Santiago?
Share of one-stop return flights from Madrid to Santiago chosen by Cheapflights users in the past 12 months, using the same stopover each way.
Lima (LIM) – chosen by Cheapflights users on 50% of one-stop itineraries from Madrid to Santiago on Cheapflights.
What’s the fastest stopover option from Madrid to Santiago?
Shortest average travel time for one-stop one-way flights from Madrid to Santiago, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by stopover airport.
Flights via Bogotá (BOG) have the shortest average one-way travel time for one-stop routes: 17h 40m.
What’s the fastest stopover option from Madrid to Santiago?
Shortest average travel time for one-stop one-way flights from Madrid to Santiago, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by stopover airport.
Flights via Bogotá (BOG) have the shortest average one-way travel time for one-stop routes: 17h 40m.
Which airport typically offers the quickest stopover for flights from Madrid to Santiago?
Average stopover duration for one-stop one-way flights from Madrid to Santiago, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Bogotá (BOG) offer the fastest connection on this route, with an average stopover time of 1h 40m.
Reviews of airlines servicing Santiago
Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated 16 September 2025.
Read through reviews of airlines operating flights from Madrid to Santiago, such as Iberia and British Airways. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Our flight kept getting delayed due to the weather and mechanical issues. Then it was canceled and rescheduled until the following day which was also delayed by a couple hours and the returning flight was also delayed so overall, we wasted a lot of time on the airport. Also, when it happened the first day, they did not want to honor a hotel or rideshare service voucher because it was hard to find an uber at 3-4 in the morning and customer service was closed that late in the day.
Our flight kept getting delayed due to the weather and mechanical issues. Then it was canceled and rescheduled until the following day which was also delayed by a couple hours and the returning flight was also delayed so overall, we wasted a lot of time on the airport. Also, when it happened the first day, they did not want to honor a hotel or rideshare service voucher because it was hard to find an uber at 3-4 in the morning and customer service was closed that late in the day.
Our flight kept getting delayed due to the weather and mechanical issues. Then it was canceled and rescheduled until the following day which was also delayed by a couple hours and the returning flight was also delayed so overall, we wasted a lot of time on the airport. Also, when it happened the first day, they did not want to honor a hotel or rideshare service voucher because it was hard to find an uber at 3-4 in the morning and customer service was closed that late in the day.
Related info for your journey
Find useful and relevant information for your journey from Madrid to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
What airports do I use to fly from Madrid to Santiago?
To fly from Madrid to Santiago, you need to book a flight from Barajas (MAD) to Arturo Merino Benitez (SCL). Nonstop flights to Santiago Arturo Merino Benitez from Madrid Barajas take 13h 15m on average. When it comes time to book airfare, you have a few options: there are 14 outbound flights from Barajas to Arturo Merino Benitez offered by 2 different airlines.
How popular is this Madrid to Santiago flight route?
This flight path from Madrid Barajas to Santiago Arturo Merino Benitez was viewed by 8 users in the past month. Keep an eye out for changes in search interest prior to high and low season.
How long is the flight from Madrid to Santiago?
A quick flight from Madrid to Santiago can take about 29h 40m. Delta provides one of the quickest options available for as low as £638. Airlines will cover a distance of 6656 mi.
What are the cheapest airlines flying from Madrid to Santiago round-trip?
Cheapflights users have booked flights from Madrid to Santiago round-trip from £448. Another airline that can offer you cheap pricing is British Airways. Users have found that Iberia is 43% cheaper than the other options available to this destination.
What are the most reliable airlines from Madrid to Santiago?
No one likes to see their flight delayed. When booking a flight from Madrid to Santiago consider choosing Finnair (90%), Japan Airlines (85%) or EL AL (85%) as they are the most reliable in getting you off to your destination on time.
What are the cheapest flights from Madrid to Santiago?
Looking at all options, your cheapest flight can be booked for £855. While the most popular route (Madrid Barajas - Santiago Arturo Merino Benitez) can be booked for £643 on average, our data indicates £933 when flying from Madrid to Santiago.
Can I find deals for business class flights from Madrid to Santiago?
Yes. Cheapflights offers flight deals from Madrid to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Madrid to Santiago?
Currently, May is the cheapest month in which you can book a flight from Madrid to Santiago (average of £1,031). Flying from Madrid to Santiago in December is currently the most expensive (average of £1,468). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Browse through other flights departing from Madrid. Flights are based on user searches made on Cheapflights and were last updated on 16 September 2025.
Explore flights to Santiago departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on 16 September 2025.
Discover the top 2 airlines that operate flights from Madrid to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 16 September 2025.
Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.
How does Cheapflights help users find flights from Madrid to Santiago?
Cheapflights makes it easy to find Madrid to Santiago flights by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.
Why should you use Cheapflights to find cheap flight tickets from Madrid to Santiago?
Millions of users choose and trust Cheapflights to book the best flight deals from Madrid to Santiago for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.
Can Cheapflights find flights from Madrid to Santiago with no change fees?
Certainly. Search results for flights to Santiago from Madrid shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.
Can Cheapflights notify me if prices for flights from Madrid to Santiago become cheaper?
Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!
100% Free
Cheapflights is completely free to use, so you can start saving the moment you arrive.
Book with Flexibility
Our users can plan ahead with confidence and find flights with no change fees
Travel Smart
Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.
We value your privacy
Cheapflights and its partners wish to use cookies or similar technologies to store and/or access information on and about your device and process personal data such as your IP address, device identifiers etc., in order to improve your experience on the site, to analyse navigation, to offer and measure personalised advertising, and to facilitate sharing on social networks. We also allow the use of third-party cookies (including those from our advertising partners) on our sites.
By clicking 'Accept', you consent to your data being processed by 0 vendors on this web site for the purposes described in this notice. You can review the vendors and their individual processing purposes on the .
To review individual processing purposes and cookie categories, please click ’Select individual purposes’. You can review your choices and withdraw your consent at any time by clicking the ’Privacy Preferences’ link in the page side navigation.