Cheap flights from Madrid, Spain to Santiago from £284
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 23/4. Fares are subject to change and may not be available on all flights or dates of travel.
MAD — SCL
2 May — 9 May1
Return
1 adult
Economy
Return
1 adult, Economy, 0 bags
Cheapflights Tip: The best prices from Madrid Barajas to Santiago Arturo Merino Benitez are usually found in March or May, booked 45 days in advance, depart on a Monday or Saturday and return on a Wednesday
Cheap flight deals from Madrid to Santiago
Enter your travel dates to find the best prices.
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Cheapest flights from Madrid to Santiago
Explore the most affordable flight options available from Madrid to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 2 April 2026.
Tue 27/1017:55
MAD
-
SCL
2 stops40h 05m
Turkish Airlines
Tue 24/1111:40
SCL
-
MAD
2 stops31h 50m
Turkish Airlines
Deal found 2/4£645
Tue 27/1017:55
MAD
-
SCL
2 stops40h 05m
Multiple Airlines
Tue 24/1114:35
SCL
-
MAD
3 stops42h 45m
Multiple Airlines
Deal found 2/4£646
Thu 26/1117:55
MAD
-
SCL
2 stops40h 05m
Multiple Airlines
Wed 9/1201:16
SCL
-
MAD
2 stops42h 14m
Multiple Airlines
Deal found 2/4£647
Thu 5/1106:00
MAD
-
SCL
2 stops29h 40m
Delta
Thu 26/1123:10
SCL
-
MAD
2 stops36h 10m
Delta
Deal found 30/3£648
Wed 2/909:50
MAD
-
SCL
1 stop27h 25m
Delta
Wed 23/920:40
SCL
-
MAD
1 stop34h 35m
Delta
Deal found 2/4£649
Sat 18/407:40
MAD
-
SCL
2 stops49h 20m
Multiple Airlines
Mon 27/411:25
SCL
-
MAD
2 stops41h 00m
Multiple Airlines
Deal found 1/4£650
Tue 21/414:35
MAD
-
SCL
2 stops46h 40m
Delta
Mon 25/520:40
SCL
-
MAD
2 stops51h 40m
Delta
Deal found 31/3£651
Wed 4/1111:15
MAD
-
SCL
1 stop24h 25m
Delta
Mon 23/1123:10
SCL
-
MAD
2 stops28h 50m
Delta
Deal found 1/4£652
Wed 14/1014:35
MAD
-
SCL
2 stops46h 40m
Delta
Wed 28/1023:10
SCL
-
MAD
1 stop29h 05m
Delta
Deal found 28/3£652
Fri 10/411:05
MAD
-
SCL
1 stop23h 40m
Avianca
Fri 24/406:40
SCL
-
MAD
1 stop20h 25m
Avianca
Deal found 30/3£655
Sat 23/507:40
MAD
-
SCL
3 stops51h 30m
Multiple Airlines
Fri 29/511:17
SCL
-
MAD
2 stops41h 08m
Multiple Airlines
Deal found 2/4£655
Tue 9/612:20
MAD
-
SCL
2 stops24h 55m
Delta
Sun 16/820:40
SCL
-
MAD
2 stops30h 50m
Delta
Deal found 30/3£656
Best flights from Madrid to Santiago
Discover carefully curated flight deals from Madrid to Santiago that have cost, travel time, and stopovers in mind to ensure you get the best travel experience. Data last updated 2 April 2026.
Wed 22/407:40
MAD
-
SCL
2 stops45h 46m
Multiple Airlines
Mon 4/511:17
SCL
-
MAD
2 stops44h 18m
Multiple Airlines
Deal found 2/4£656
Sun 30/809:50
MAD
-
SCL
1 stop27h 25m
Delta
Mon 14/920:40
SCL
-
MAD
2 stops28h 40m
Delta
Deal found 28/3£696
Fri 18/911:25
MAD
-
SCL
1 stop27h 10m
LEVEL
Sat 3/1011:20
SCL
-
MAD
1 stop29h 10m
LEVEL
Deal found 30/3£884
Mon 14/923:59
MAD
-
SCL
Nonstop13h 26m
Iberia
Mon 28/911:40
SCL
-
MAD
Nonstop12h 40m
Iberia
Deal found 1/4£903
Thu 11/607:40
MAD
-
SCL
2 stops30h 50m
Turkish Airlines
Thu 25/610:15
SCL
-
MAD
2 stops24h 40m
Turkish Airlines
Deal found 31/3£953
Tue 1/909:50
MAD
-
SCL
1 stop27h 25m
Delta
Wed 30/920:40
SCL
-
MAD
1 stop34h 35m
Delta
Deal found 1/4£731
Fri 15/514:40
MAD
-
SCL
3 stops44h 30m
Multiple Airlines
Fri 29/511:17
SCL
-
MAD
2 stops41h 08m
Multiple Airlines
Deal found 2/4£731
Fri 4/909:50
MAD
-
SCL
1 stop27h 25m
Delta
Tue 22/920:40
SCL
-
MAD
1 stop34h 35m
Delta
Deal found 30/3£739
Wed 1/707:40
MAD
-
SCL
2 stops41h 43m
Multiple Airlines
Tue 4/810:15
SCL
-
MAD
2 stops30h 20m
Multiple Airlines
Deal found 2/4£825
Wed 16/909:50
MAD
-
SCL
1 stop27h 25m
Delta
Wed 30/920:40
SCL
-
MAD
1 stop34h 35m
Delta
Deal found 28/3£774
Mon 4/506:00
MAD
-
SCL
2 stops31h 15m
Delta
Sun 24/520:40
SCL
-
MAD
2 stops31h 15m
Delta
Deal found 29/3£822
Thu 7/509:50
MAD
-
SCL
1 stop27h 25m
Delta
Thu 21/520:40
SCL
-
MAD
2 stops55h 15m
Delta
Deal found 30/3£868
Direct flights from Madrid to Santiago
Explore direct flight options from Madrid to Santiago based on user searches, and compare prices and availability for your desired travel dates. Data last updated 2 April 2026.
Fri 15/513:20
MAD
-
SCL
Nonstop13h 20m
Iberia
Fri 22/510:40
SCL
-
MAD
Nonstop12h 40m
Iberia
Deal found 31/3£831
Wed 6/513:20
MAD
-
SCL
Nonstop13h 20m
Iberia
Sun 24/522:00
SCL
-
MAD
Nonstop12h 40m
Iberia
Deal found 30/3£834
Thu 30/423:59
MAD
-
SCL
Nonstop13h 26m
Iberia
Fri 22/522:20
SCL
-
MAD
Nonstop12h 40m
Iberia
Deal found 1/4£843
Fri 15/513:20
MAD
-
SCL
Nonstop13h 20m
Iberia
Fri 29/510:40
SCL
-
MAD
Nonstop12h 40m
Iberia
Deal found 1/4£845
Mon 4/523:59
MAD
-
SCL
Nonstop13h 26m
Iberia
Sat 23/510:40
SCL
-
MAD
Nonstop12h 40m
Iberia
Deal found 2/4£851
Mon 1/613:20
MAD
-
SCL
Nonstop13h 20m
Iberia
Wed 10/610:40
SCL
-
MAD
Nonstop12h 40m
Iberia
Deal found 2/4£871
Fri 18/913:15
MAD
-
SCL
Nonstop12h 20m
LATAM Airlines
Sun 4/1019:00
SCL
-
MAD
Nonstop13h 55m
LATAM Airlines
Deal found 30/3£889
Fri 18/913:15
MAD
-
SCL
Nonstop12h 20m
LATAM Airlines
Sat 3/1019:00
SCL
-
MAD
Nonstop13h 55m
LATAM Airlines
Deal found 30/3£891
Fri 18/913:20
MAD
-
SCL
Nonstop13h 20m
Iberia
Sun 4/1011:40
SCL
-
MAD
Nonstop12h 40m
Iberia
Deal found 30/3£902
Tue 25/813:20
MAD
-
SCL
Nonstop13h 20m
Iberia
Fri 25/923:20
SCL
-
MAD
Nonstop12h 40m
Iberia
Deal found 29/3£903
Wed 26/813:20
MAD
-
SCL
Nonstop13h 20m
Iberia
Sat 26/911:40
SCL
-
MAD
Nonstop12h 40m
Iberia
Deal found 2/4£909
Mon 4/523:59
MAD
-
SCL
Nonstop13h 26m
Iberia
Mon 11/510:40
SCL
-
MAD
Nonstop12h 40m
Iberia
Deal found 1/4£926
Last-minute flights from Madrid to Santiago
Discover last-minute flight deals from Madrid to Santiago. Data last updated 2 April 2026 and is based on user searches.
Fri 10/411:05
MAD
-
SCL
1 stop23h 40m
Avianca
Fri 24/406:40
SCL
-
MAD
1 stop20h 25m
Avianca
Deal found 30/3£655
Sat 18/407:40
MAD
-
SCL
2 stops49h 20m
Multiple Airlines
Mon 27/411:25
SCL
-
MAD
2 stops41h 00m
Multiple Airlines
Deal found 1/4£650
Tue 21/412:45
MAD
-
SCL
1 stop24h 30m
Delta
Sun 24/520:40
SCL
-
MAD
2 stops55h 15m
Delta
Deal found 31/3£651
Tue 21/418:25
MAD
-
SCL
2 stops58h 18m
Multiple Airlines
Mon 4/511:17
SCL
-
MAD
2 stops41h 08m
Multiple Airlines
Deal found 2/4£656
Mon 4/512:45
MAD
-
SCL
1 stop24h 30m
Delta
Mon 25/520:40
SCL
-
MAD
2 stops31h 15m
Delta
Deal found 1/4£652
Wed 6/518:25
MAD
-
SCL
2 stops44h 05m
Turkish Airlines
Sun 24/510:15
SCL
-
MAD
2 stops42h 10m
Turkish Airlines
Deal found 29/3£666
Sun 10/502:20
MAD
-
SCL
1 stop27h 00m
Avianca
Tue 26/500:30
SCL
-
MAD
1 stop26h 35m
Avianca
Deal found 30/3£657
Wed 13/509:50
MAD
-
SCL
1 stop27h 25m
Delta
Sat 23/520:40
SCL
-
MAD
2 stops51h 40m
Delta
Deal found 30/3£652
Sun 17/508:10
MAD
-
SCL
1 stop21h 10m
Avianca
Sun 24/506:40
SCL
-
MAD
1 stop20h 25m
Avianca
Deal found 2/4£661
Thu 21/512:20
MAD
-
SCL
2 stops24h 55m
Delta
Wed 3/620:40
SCL
-
MAD
2 stops27h 40m
Delta
Deal found 31/3£668
Sat 23/507:40
MAD
-
SCL
3 stops51h 30m
Multiple Airlines
Fri 29/511:17
SCL
-
MAD
2 stops41h 08m
Multiple Airlines
Deal found 2/4£655
One-way flights from Madrid to Santiago
Search for one-way flight options from Madrid to Santiago. Find affordable one-way fares based on user searches. Data last updated 2 April 2026.
Thu 23/411:05
MAD
-
SCL
1 stop23h 40m
Avianca
Deal found 31/3£284
Fri 24/402:20
MAD
-
SCL
1 stop17h 55m
Avianca
Deal found 31/3£320
Sun 14/620:20
MAD
-
SCL
2 stops33h 00m
Avianca
Deal found 31/3£338
Sun 17/523:59
MAD
-
SCL
Nonstop13h 26m
Iberia
Deal found 1/4£368
Wed 2/908:10
MAD
-
SCL
1 stop21h 10m
Avianca
Deal found 30/3£415
Tue 25/817:20
MAD
-
SCL
1 stop17h 25m
Avianca
Deal found 2/4£417
Tue 25/806:00
MAD
-
SCL
2 stops47h 20m
Multiple Airlines
Deal found 2/4£454
Fri 18/913:15
MAD
-
SCL
Nonstop12h 20m
LATAM Airlines
Deal found 30/3£479
Tue 25/823:55
MAD
-
SCL
Nonstop13h 20m
LATAM Airlines
Deal found 2/4£489
Find flight deals from Madrid to Santiago
Discover tips and strategies to find the most affordable flight options for your journey from Madrid (MAD) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 2 April 2026.
Customise your flight search to find flights from Madrid to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 2 April 2026.
Use the filters below to find and compare flights from Madrid to Santiago that are best for you.
Fly from
Fly to
Route
Depart
Return
Price
Cheapest return flight
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Wed 22/4
07:40-23:26
2 stops45h 46m
Santiago Arturo Merino Benitez
Mon 4/5
11:17-13:35
2 stops44h 18m
£656
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Sun 30/8
09:50-07:15
1 stop27h 25m
Santiago Arturo Merino Benitez
Mon 14/9
20:40-06:20
2 stops28h 40m
£696
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Tue 1/9
09:50-07:15
1 stop27h 25m
Santiago Arturo Merino Benitez
Wed 30/9
20:40-12:15
1 stop34h 35m
£731
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Fri 15/5
14:40-05:10
3 stops44h 30m
Santiago Arturo Merino Benitez
Fri 29/5
11:17-10:25
2 stops41h 08m
£731
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Fri 4/9
09:50-07:15
1 stop27h 25m
Santiago Arturo Merino Benitez
Tue 22/9
20:40-12:15
1 stop34h 35m
£739
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Wed 16/9
09:50-08:15
1 stop27h 25m
Santiago Arturo Merino Benitez
Wed 30/9
20:40-12:15
1 stop34h 35m
£774
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Mon 4/5
06:00-07:15
2 stops31h 15m
Santiago Arturo Merino Benitez
Sun 24/5
20:40-09:55
2 stops31h 15m
£822
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Wed 1/7
07:40-19:23
2 stops41h 43m
Santiago Arturo Merino Benitez
Tue 4/8
10:15-22:35
2 stops30h 20m
£825
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Thu 7/5
09:50-07:15
1 stop27h 25m
Santiago Arturo Merino Benitez
Thu 21/5
20:40-09:55
2 stops55h 15m
£868
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Fri 18/9
11:25-09:35
1 stop27h 10m
Santiago Arturo Merino Benitez
Sat 3/10
11:20-21:30
1 stop29h 10m
£884
Flights are sorted by cheapest return flights first.
Deals found on 31/3
Showing 1-10 of 23 resultsSorted by cheapest first
1
2
3
Best time to book a flight from Madrid to Santiago
Have a flexible travel schedule? Discover the best time to fly to Santiago from Madrid with our price prediction graph.
MAD-SCL
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Madrid to Santiago
Prices
Delays
How far ahead should I book a flight from Madrid to Santiago?
Use this chart to determine the optimal time to book a return flight from Madrid to Santiago. Price data was last updated on 2 April 2026.
The price you pay for your flight from Madrid to Santiago may vary depending on when you book. For the best chance of a lower fare, look to book 45 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Madrid to Santiago?
Currently, March is the cheapest month in which you can book a flight from Madrid to Santiago (average of £379). Flying from Madrid to Santiago in July is currently the most expensive (average of £812). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MAD to SCL?
Find hourly flight availability from Madrid to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 2 April 2026.
When flying from Madrid to Santiago, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
How much does it cost for a return flight from Madrid to Santiago?
How often are flights from Madrid to Santiago delayed?
About 15% of weekly flights between Madrid and Santiago have experienced delays in the past year, with the average delay time being 135 minutes.
What is the most punctual flight time for Madrid to Santiago flights?
Historically, flights departing at night are less likely to be delayed, whereas flights leaving in the early afternoon tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Saturday tends to have the lowest number of delays on this route, whereas Friday has historically faced a higher average of delays compared to other days of the week.
Which airline has the best punctuality record on Madrid to Santiago flights?
Over the past year, LATAM Airlines have had the lowest number of delays on this route, with just 12% of flights being delayed.
Reviews of airlines servicing Santiago
Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated 2 April 2026.
Read through reviews of airlines operating flights from Madrid to Santiago, such as LATAM Airlines and Iberia. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Plane was late in FLN and missed connection in GRU. No alternative was given to me until 6 hours later and I was delayed by over 12 hours total.
Related info for your journey
Find useful and relevant information for your journey from Madrid to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
What airports do I use to fly from Madrid to Santiago?
To fly from Madrid to Santiago, you need to book a flight from Barajas (MAD) to Arturo Merino Benitez (SCL). Nonstop flights to Santiago Arturo Merino Benitez from Madrid Barajas take 12h 20m on average. When it comes time to book airfare, you have a few options: there are 4 outbound flights from Barajas to Arturo Merino Benitez offered by 2 different airlines.
How popular is this Madrid to Santiago flight route?
This flight path from Madrid Barajas to Santiago Arturo Merino Benitez was viewed by 17 users in the past month. Keep an eye out for changes in search interest prior to high and low season.
How long is the flight from Madrid to Santiago?
A quick flight from Madrid to Santiago can take about 46h 40m. Delta provides one of the quickest options available for as low as £651. Airlines will cover a distance of 6656 mi.
What are the cheapest airlines flying from Madrid to Santiago round-trip?
Cheapflights users have booked flights from Madrid to Santiago round-trip from £611. Another airline that can offer you cheap pricing is LATAM Airlines. Users have found that Iberia is 27% cheaper than the other options available to this destination.
What are the most reliable airlines from Madrid to Santiago?
No one likes to see their flight delayed. When booking a flight from Madrid to Santiago consider choosing Japan Airlines (93%), EL AL (93%) or Finnair (92%) as they are the most reliable in getting you off to your destination on time.
What are the cheapest flights from Madrid to Santiago?
Looking at all options, your cheapest flight can be booked for £609. While the most popular route (Madrid Barajas - Santiago Arturo Merino Benitez) can be booked for £817 on average, our data indicates £805 when flying from Madrid to Santiago.
Can I find deals for business class flights from Madrid to Santiago?
Yes. Cheapflights offers flight deals from Madrid to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Madrid to Santiago?
Currently, March is the cheapest month in which you can book a flight from Madrid to Santiago (average of £379). Flying from Madrid to Santiago in July is currently the most expensive (average of £812). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Explore flights to Santiago departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on 2 April 2026.
Discover the top 2 airlines that operate flights from Madrid to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 2 April 2026.
Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.
How does Cheapflights help users find flights from Madrid to Santiago?
Cheapflights makes it easy to find Madrid to Santiago flights by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.
Why should you use Cheapflights to find cheap flight tickets from Madrid to Santiago?
Millions of users choose and trust Cheapflights to book the best flight deals from Madrid to Santiago for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.
Can Cheapflights find flights from Madrid to Santiago with no change fees?
Certainly. Search results for flights to Santiago from Madrid shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.
Can Cheapflights notify me if prices for flights from Madrid to Santiago become cheaper?
Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!
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