Find flights
Deals
When to book
Airlines
FAQs

Cheap flights from Madrid, Spain to Santiago from £379

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/12. Fares are subject to change and may not be available on all flights or dates of travel.
MAD — SCL
20 Nov — 27 Nov1
1 adult
1 adult, Economy

Cheapflights Tip: The best prices from Madrid Barajas to Santiago Arturo Merino Benitez are usually found in March or February, booked 88 days in advance, depart on a Wednesday or Thursday and return on a Monday

Find flight deals from Madrid to Santiago

Enter your travel dates to find the best prices.

Cheapest flights from Madrid to Santiago
Explore the most affordable flight options available from Madrid to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 21 October 2025.

Thu 4/1213:35MAD - SCL
2 stops50h 40mAir Canada
Sun 1/208:35SCL - MAD
1 stop23h 30mAir Canada
Deal found 20/10£630
Sat 22/1113:05MAD - SCL
2 stops46h 35mDelta
Thu 4/1223:10SCL - MAD
1 stop30h 05mDelta
Deal found 20/10£634
Sun 23/1106:00MAD - SCL
2 stops29h 40mDelta
Sun 7/1223:10SCL - MAD
2 stops38h 30mDelta
Deal found 20/10£641
Fri 7/1111:05MAD - SCL
2 stops49h 45mUnited Airlines
Fri 14/1122:45SCL - MAD
2 stops53h 20mUnited Airlines
Deal found 20/10£643
Mon 10/1106:00MAD - SCL
2 stops29h 40mDelta
Mon 24/1123:10SCL - MAD
2 stops38h 30mDelta
Deal found 21/10£648
Mon 29/1210:00MAD - SCL
2 stops49h 40mDelta
Sun 18/123:15SCL - MAD
1 stop30h 00mDelta
Deal found 19/10£652
Tue 25/1106:00MAD - SCL
2 stops29h 40mDelta
Tue 9/1223:10SCL - MAD
2 stops31h 05mDelta
Deal found 19/10£657
Wed 26/1107:30MAD - SCL
2 stops28h 10mDelta
Sat 6/1223:10SCL - MAD
1 stop30h 05mDelta
Deal found 19/10£659
Sun 23/1110:00MAD - SCL
2 stops25h 40mDelta
Thu 27/1123:10SCL - MAD
1 stop28h 50mDelta
Deal found 19/10£660
Sat 22/1106:00MAD - SCL
2 stops30h 50mUnited Airlines
Fri 5/1222:45SCL - MAD
2 stops30h 30mUnited Airlines
Deal found 21/10£662
Tue 11/1106:00MAD - SCL
2 stops29h 40mDelta
Tue 25/1123:10SCL - MAD
2 stops33h 00mDelta
Deal found 20/10£664

Cheap flight deals from Madrid to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Madrid (MAD) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 21 October 2025.

Round-trip from

£630

One-way from

£379

Popular in

December

Cheapest in

March

Average price

£799

Good round-trip deal

£926 or less

Good one-way deal

£508 or less
Air Canada
  • Air Canada
  • 4/12-1/2
  • 3 total stops
  • 74h 10m total
  • Madrid to Santiago
Search Deals
United Airlines
  • United Airlines
  • 3/12
  • 2 total stops
  • 47h 05m total
  • Madrid to Santiago
Search Deals
Highest demand for flights based on searches. 4% potential increase in price (£30 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease (£15 potential savings vs. average return price).
Search Deals
Average for round-trip flights in October 2025
Search Deals
Price to beat on a round-trip flight from Madrid Barajas to Santiago Arturo Merino Benitez.
Search Deals
Price to beat on a one-way flight from Madrid Barajas to Santiago Arturo Merino Benitez.
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Madrid to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 21 October 2025.
Use the filters below to find and compare flights from Madrid to Santiago that are best for you.

Fly from

Madrid

Fly to

Santiago

Route

Depart

Return

Price

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Tue 10/3

12:55-22:15

Nonstop13h 20m

Santiago Arturo Merino Benitez

Fri 10/4

10:55-05:35

Nonstop12h 40m

£647

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Tue 11/11

11:15-07:40

1 stop24h 25m

Santiago Arturo Merino Benitez

Tue 25/11

23:10-09:15

1 stop30h 05m

£652

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Mon 24/11

10:00-07:40

2 stops25h 40m

Santiago Arturo Merino Benitez

Thu 27/11

23:10-08:00

2 stops52h 50m

£660

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Sun 23/11

06:00-07:40

2 stops29h 40m

Santiago Arturo Merino Benitez

Sun 7/12

23:10-09:15

1 stop30h 05m

£660

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Sun 23/11

10:00-07:40

2 stops25h 40m

Santiago Arturo Merino Benitez

Thu 27/11

23:10-08:00

1 stop28h 50m

£660

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Sat 22/11

10:00-07:40

2 stops49h 40m

Santiago Arturo Merino Benitez

Tue 25/11

23:10-08:00

2 stops52h 50m

£660

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Sun 23/11

10:00-07:40

2 stops49h 40m

Santiago Arturo Merino Benitez

Wed 26/11

23:10-08:00

2 stops28h 50m

£660

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Mon 24/11

11:15-07:40

1 stop24h 25m

Santiago Arturo Merino Benitez

Wed 26/11

23:10-08:00

2 stops28h 50m

£660

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Sat 22/11

08:25-08:50

2 stops52h 25m

£382

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Wed 19/11

00:40-14:05

1 stop17h 25m

£402

Flights are sorted by cheapest return flights first.

Deals found on 20/10

Showing 1-10 of 17 results
1
2

Best time to book a flight from Madrid to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Madrid with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Madrid to Santiago

How far ahead should I book a flight from Madrid to Santiago?

Use this chart to determine the optimal time to book a return flight from Madrid to Santiago. Price data was last updated on 17 October 2025.

The price you pay for your flight from Madrid to Santiago may vary depending on when you book. For the best chance of a lower fare, look to book 88 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Madrid to Santiago?

Currently, January is the cheapest month in which you can book a flight from Madrid to Santiago (average of £422). Flying from Madrid to Santiago in July is currently the most expensive (average of £662). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MAD to SCL?

Find hourly flight availability from Madrid to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 21 October 2025.

A simple way to save on the total cost of your ticket is to fly from Madrid to Santiago in the morning. If you’re flexible enough to do this you can expect to save up to 11% on your trip compared to booking a flight in the afternoon.

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated 21 October 2025.
Read through reviews of airlines operating flights from Madrid to Santiago, such as LATAM Airlines, Iberia, andBritish Airways. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
LATAM Airlines
7.5
Good
1,868 reviews
Check prices

Crew

8.0

Comfort

7.3

Entertainment

7.0

Overall

7.5

Boarding

7.6

Food

6.7

Reviews

1 / 20
2.0
Mediocre

Anonymous,Oct 2025

MIA - GRU

Terrible baggage service! Almost lost my connection flight in SP
LATAM Airlines
7.5
Good
1,868 reviews
LATAM Airlines
7.5
Good
1,868 reviews
Check prices

Crew

8.0

Comfort

7.3

Entertainment

7.0

Overall

7.5

Boarding

7.6

Food

6.7

Reviews

1 / 20
2.0
Mediocre

Anonymous,Oct 2025

MIA - GRU

Terrible baggage service! Almost lost my connection flight in SP
Iberia
7.0
Good
2,996 reviews
LATAM Airlines
7.5
Good
1,868 reviews
Check prices

Crew

8.0

Comfort

7.3

Entertainment

7.0

Overall

7.5

Boarding

7.6

Food

6.7

Reviews

1 / 20
2.0
Mediocre

Anonymous,Oct 2025

MIA - GRU

Terrible baggage service! Almost lost my connection flight in SP
British Airways
6.7
Okay
7,461 reviews
LATAM Airlines
7.5
Good
1,868 reviews
Check prices

Crew

8.0

Comfort

7.3

Entertainment

7.0

Overall

7.5

Boarding

7.6

Food

6.7

Reviews

1 / 20
2.0
Mediocre

Anonymous,Oct 2025

MIA - GRU

Terrible baggage service! Almost lost my connection flight in SP

Related info for your journey

Find useful and relevant information for your journey from Madrid to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Madrid to Santiago?

    To fly from Madrid to Santiago, you need to book a flight from Barajas (MAD) to Arturo Merino Benitez (SCL). Nonstop flights to Santiago Arturo Merino Benitez from Madrid Barajas take 13h 15m on average. When it comes time to book airfare, you have a few options: there are 13 outbound flights from Barajas to Arturo Merino Benitez offered by 3 different airlines.

  • How popular is this Madrid to Santiago flight route?

    This flight path from Madrid Barajas to Santiago Arturo Merino Benitez was viewed by 12 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Madrid to Santiago?

    A quick flight from Madrid to Santiago can take about 13h 20m. Iberia provides one of the quickest options available for as low as £647. Airlines will cover a distance of 6656 mi. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.

  • What are the cheapest airlines flying from Madrid to Santiago round-trip?

    Cheapflights users have booked flights from Madrid to Santiago round-trip from £454. Other airlines that can offer you cheap pricing are LATAM Airlines, from £513, and British Airways, from £516. Users have found that Iberia is 43% cheaper than the other options available to this destination.

  • What are the cheapest airlines to fly from Madrid to Santiago one-way?

    To fly one-way, consider booking your trip with United Airlines, which is currently one of the cheapest options available, starting at £382. LATAM Airlines flights start at £402 while deals on Avianca start at £422 one-way.

  • What are the most reliable airlines from Madrid to Santiago?

    No one likes to see their flight delayed. When booking a flight from Madrid to Santiago consider choosing Japan Airlines (97%), Finnair (97%) or EL AL (97%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Madrid to Santiago?

    Looking at all options, your cheapest flight can be booked for £452. While the most popular route (Madrid Barajas - Santiago Arturo Merino Benitez) can be booked for £652 on average, our data indicates £737 when flying from Madrid to Santiago.

  • Can I find deals for flights from Madrid to Santiago that include hotel bookings?

    Yes. In addition to deals on Madrid to Santiago flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Madrid to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Madrid to Santiago.

  • Can I find deals for business class flights from Madrid to Santiago?

    Yes. Cheapflights offers flight deals from Madrid to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Madrid to Santiago?

    Currently, January is the cheapest month in which you can book a flight from Madrid to Santiago (average of £422). Flying from Madrid to Santiago in July is currently the most expensive (average of £662). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Complete your trip

Complete your trip to Santiago by adding a car hire and/or hotel booking to your travel itinerary.
Santiago car hire
Santiago Arturo Merino Benitez Airport car hire
Punta Arenas car hire
Balmaceda car hire
Puerto Montt car hire
Lastarria car hire

Top 3 airlines flying from Madrid to Santiago

Discover the top 3 airlines that operate flights from Madrid to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 21 October 2025.
AirlineCheapestAverageFlexibilityOn-time
IberiaCheapest£454Average£923FlexibilityNo cancel feeOn-time77%
Search Iberia flights
LATAM AirlinesCheapest£513Average£928FlexibilityNo cancel feeOn-time81%
Search LATAM Airlines flights
British AirwaysCheapest£516Average£549FlexibilityNo cancel feeOn-time70%
Search British Airways flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Madrid to Santiago?

Cheapflights makes it easy to find Madrid to Santiago flights by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

Why should you use Cheapflights to find cheap flight tickets from Madrid to Santiago?

Millions of users choose and trust Cheapflights to book the best flight deals from Madrid to Santiago for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.

Can Cheapflights find flights from Madrid to Santiago with no change fees?

Certainly. Search results for flights to Santiago from Madrid shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Madrid to Santiago become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.