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Cheap flights from Madrid, Spain to Santiago from £346

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 25/8. Fares are subject to change and may not be available on all flights or dates of travel.
MAD — SCL
23 aug. — 30 aug.1
1 adult
1 adult, Economy, 0 bags
Cheapflights Tip: The best prices from Madrid Barajas to Santiago Arturo Merino Benitez are usually found in May or March, booked 45 days in advance, depart on a Friday or Sunday and return on a Sunday

Cheap flight deals from Madrid to Santiago

Enter your travel dates to find the best prices.

Cheapest flights from Madrid to Santiago
Explore the most affordable flight options available from Madrid to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 24 juli 2026.

fre. 11/908:10
MAD
-
SCL
1 stop26h 35m
Avianca
søn. 27/907:40
SCL
-
MAD
1 stop17h 30m
Avianca
Deal found 24/7£598
søn. 13/908:10
MAD
-
SCL
1 stop21h 10m
Avianca
tir. 29/907:40
SCL
-
MAD
1 stop35h 40m
Avianca
Deal found 21/7£600
fre. 11/908:10
MAD
-
SCL
1 stop21h 10m
Avianca
lør. 26/916:20
SCL
-
MAD
1 stop16h 45m
Avianca
Deal found 22/7£605
tor. 5/1110:00
MAD
-
SCL
2 stops49h 40m
Delta
ons. 25/1123:10
SCL
-
MAD
2 stops28h 50m
Delta
Deal found 22/7£606
tor. 5/1111:55
MAD
-
SCL
1 stop23h 45m
Delta
tor. 12/1123:10
SCL
-
MAD
2 stops28h 50m
Delta
Deal found 21/7£607
fre. 11/909:50
MAD
-
SCL
1 stop27h 25m
Delta
søn. 27/920:40
SCL
-
MAD
2 stops28h 40m
Delta
Deal found 23/7£612
ons. 21/1009:50
MAD
-
SCL
1 stop27h 25m
Delta
ons. 4/1123:10
SCL
-
MAD
2 stops34h 10m
Delta
Deal found 20/7£618
fre. 4/909:50
MAD
-
SCL
1 stop27h 25m
Delta
man. 14/920:40
SCL
-
MAD
2 stops39h 05m
Delta
Deal found 22/7£619
man. 23/1111:55
MAD
-
SCL
1 stop23h 45m
Delta
tir. 8/1223:10
SCL
-
MAD
2 stops32h 20m
Delta
Deal found 21/7£620
tor. 20/809:50
MAD
-
SCL
1 stop27h 25m
Delta
søn. 30/820:40
SCL
-
MAD
2 stops32h 40m
Delta
Deal found 20/7£621
man. 14/910:05
MAD
-
SCL
2 stops27h 10m
Delta
tir. 13/1020:40
SCL
-
MAD
2 stops32h 15m
Delta
Deal found 24/7£622
fre. 11/906:00
MAD
-
SCL
2 stops31h 15m
Delta
man. 12/1020:40
SCL
-
MAD
2 stops28h 40m
Delta
Deal found 22/7£623

Find flight deals from Madrid to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Madrid (MAD) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 24 juli 2026.

Round-trip from

£598

One-way from

£346

Popular in

July

Cheapest in

May

Average price

£1,095

Good round-trip deal

£648 or less

Good one-way deal

£716 or less
Avianca
  • Avianca
  • 11/9-27/9
  • 2 total stops
  • 44h 05m total
  • Madrid to Santiago
Search Deals
Avianca
  • Avianca
  • 25/8
  • 1 total stop
  • 26h 35m total
  • Madrid to Santiago
Search Deals
Highest demand for flights based on searches. 10% potential increase in price (£72 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease (£19 potential savings vs. average return price).
Search Deals
Average for round-trip flights in July 2026
Search Deals
Price to beat on a round-trip flight from Madrid Barajas to Santiago Arturo Merino Benitez.
Search Deals
Price to beat on a one-way flight from Madrid Barajas to Santiago Arturo Merino Benitez.
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Madrid to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 24 juli 2026.
Use the filters below to find and compare flights from Madrid to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

fre. 11/9

06:00-08:15

2 stops31h 15m

Santiago Arturo Merino Benitez

man. 12/10

20:40-06:20

2 stops28h 40m

£623

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

man. 14/9

06:00-08:15

2 stops31h 15m

Santiago Arturo Merino Benitez

lør. 26/9

20:40-06:20

2 stops28h 40m

£630
Fastest return journey

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

man. 14/9

10:25-08:15

2 stops26h 50m

Santiago Arturo Merino Benitez

tir. 29/9

20:40-06:20

2 stops28h 40m

£631

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

tor. 20/8

12:20-07:15

2 stops24h 55m

Santiago Arturo Merino Benitez

søn. 30/8

20:40-11:20

2 stops32h 40m

£638

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

ons. 20/1

10:00-06:40

2 stops24h 40m

Santiago Arturo Merino Benitez

tor. 4/2

23:10-10:55

1 stop31h 45m

£642

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

ons. 23/9

09:50-08:15

1 stop27h 25m

Santiago Arturo Merino Benitez

søn. 27/9

20:40-09:55

2 stops32h 15m

£700

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

man. 19/10

12:00-09:30

2 stops50h 30m

Santiago Arturo Merino Benitez

man. 26/10

11:45-13:15

2 stops45h 30m

£714

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

tor. 10/9

06:00-08:15

2 stops31h 15m

Santiago Arturo Merino Benitez

tor. 24/9

20:40-06:20

2 stops28h 40m

£716

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

ons. 20/1

17:55-08:25

3 stops42h 30m

Santiago Arturo Merino Benitez

tor. 4/2

11:45-23:35

2 stops31h 50m

£719

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

tor. 3/9

09:50-07:15

1 stop27h 25m

Santiago Arturo Merino Benitez

tor. 3/6

20:40-06:20

2 stops51h 40m

£735

Flights are sorted by cheapest return flights first.

Deals found on 20/7

Showing 1-10 of 21 resultsSorted by cheapest first
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2
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Best time to book a flight from Madrid to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Madrid with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Madrid to Santiago

How far ahead should I book a flight from Madrid to Santiago?

The price you pay for your flight from Madrid to Santiago may vary depending on when you book. For the best chance of a lower fare, look to book 44 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Madrid to Santiago?

Currently, May is the cheapest month in which you can book a flight from Madrid to Santiago (average of £684). Flying from Madrid to Santiago in July is currently the most expensive (average of £1,095). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MAD to SCL?

Find hourly flight availability from Madrid to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 24 juli 2026.

When flying from Madrid to Santiago, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

How much does it cost for a return flight from Madrid to Santiago?

Airfare is below average for this route at the moment.

Madrid to Santiago flights typically cost between £868 and £1,120 in September.
The cheapest return price found within the last 5 days was £598 on Avianca (11 Sept–27 Sept).

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated 24 juli 2026.
Read through reviews of airlines operating flights from Madrid to Santiago, such as LATAM Airlines and Iberia. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
LATAM Airlines
7.4
Good
1,965 reviews
Check prices

Boarding

7.5

Entertainment

7.0

Food

6.7

Comfort

7.3

Overall

7.4

Crew

8.0

Reviews

1 / 20
6.0
Good

Juan,Apr 2026

BOG - CLO

Very old aircraft and it was very dirty in the seats and floor
LATAM Airlines
7.4
Good
1,965 reviews
LATAM Airlines
7.4
Good
1,965 reviews
Check prices

Boarding

7.5

Entertainment

7.0

Food

6.7

Comfort

7.3

Overall

7.4

Crew

8.0

Reviews

1 / 20
6.0
Good

Juan,Apr 2026

BOG - CLO

Very old aircraft and it was very dirty in the seats and floor
Iberia
7.0
Good
3,256 reviews
LATAM Airlines
7.4
Good
1,965 reviews
Check prices

Boarding

7.5

Entertainment

7.0

Food

6.7

Comfort

7.3

Overall

7.4

Crew

8.0

Reviews

1 / 20
6.0
Good

Juan,Apr 2026

BOG - CLO

Very old aircraft and it was very dirty in the seats and floor

Related info for your journey

Find useful and relevant information for your journey from Madrid to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Madrid to Santiago?

    To fly from Madrid to Santiago, you need to book a flight from Barajas (MAD) to Arturo Merino Benitez (SCL). Nonstop flights to Santiago Arturo Merino Benitez from Madrid Barajas take 13h 25m on average. When it comes time to book airfare, you have a few options: there are 13 outbound flights from Barajas to Arturo Merino Benitez offered by 2 different airlines.

  • How popular is this Madrid to Santiago flight route?

    This flight path from Madrid Barajas to Santiago Arturo Merino Benitez was viewed by 26 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Madrid to Santiago?

    A quick flight from Madrid to Santiago can take about 31h 15m. Delta provides one of the quickest options available for as low as £623. Airlines will cover a distance of 6656 mi.

  • What are the cheapest airlines flying from Madrid to Santiago round-trip?

    Cheapflights users have booked flights from Madrid to Santiago round-trip from £608. Another airline that can offer you cheap pricing is LATAM Airlines. Users have found that Iberia is 26% cheaper than the other options available to this destination.

  • What are the most reliable airlines from Madrid to Santiago?

    No one likes to see their flight delayed. When booking a flight from Madrid to Santiago consider choosing Japan Airlines (88%), EL AL (88%) or Finnair (83%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Madrid to Santiago?

    Looking at all options, your cheapest flight can be booked for £644. While the most popular route (Madrid Barajas - Santiago Arturo Merino Benitez) can be booked for £631 on average, our data indicates £1,464 when flying from Madrid to Santiago.

  • Can I find deals for flights from Madrid to Santiago that include hotel bookings?

    Yes. In addition to deals on Madrid to Santiago flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Madrid to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Madrid to Santiago.

  • Can I find deals for business class flights from Madrid to Santiago?

    Yes. Cheapflights offers flight deals from Madrid to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Madrid to Santiago?

    Currently, May is the cheapest month in which you can book a flight from Madrid to Santiago (average of £684). Flying from Madrid to Santiago in July is currently the most expensive (average of £1,095). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Complete your trip

Complete your trip to Santiago by adding a car hire and/or hotel booking to your travel itinerary.
Santiago car hire
Santiago Arturo Merino Benitez Airport car hire
Punta Arenas car hire
Balmaceda car hire
Lastarria car hire

Top 2 airlines flying from Madrid to Santiago

Discover the top 2 airlines that operate flights from Madrid to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 24 juli 2026.
AirlineCheapestAverageFlexibilityOn-time
IberiaCheapest£608Average£931FlexibilityNo cancel feeOn-time77%
Search Iberia flights
LATAM AirlinesCheapest£754Average£933FlexibilityNo cancel feeOn-time81%
Search LATAM Airlines flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Madrid to Santiago?

Cheapflights makes it easy to find Madrid to Santiago flights by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

Why should you use Cheapflights to find cheap flight tickets from Madrid to Santiago?

Millions of users choose and trust Cheapflights to book the best flight deals from Madrid to Santiago for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.

Can Cheapflights find flights from Madrid to Santiago with no change fees?

Certainly. Search results for flights to Santiago from Madrid shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Madrid to Santiago become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

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