Cheap flights from Madrid, Spain to Santiago from £395
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 15/4. Fares are subject to change and may not be available on all flights or dates of travel.
MAD — SCL
27 Feb — 6 Mar1
Return
1 adult
Economy
Return
1 adult, Economy, 0 bags
Cheapflights Tip: The best prices from Madrid Barajas to Santiago Arturo Merino Benitez are usually found in March or May, booked 72 days in advance, depart on a Tuesday or Monday and return on a Monday
Cheap flight deals from Madrid to Santiago
Enter your travel dates to find the best prices.
Cheapest flights from Madrid to Santiago
Explore the most affordable flight options available from Madrid to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 28 January 2026.
Tue 3/211:15
MAD
-
SCL
1 stop24h 25m
Delta
Thu 19/223:10
SCL
-
MAD
1 stop30h 05m
Delta
Deal found 26/1£602
Tue 3/211:15
MAD
-
SCL
1 stop24h 25m
Delta
Mon 16/223:10
SCL
-
MAD
2 stops28h 50m
Delta
Deal found 26/1£603
Sat 7/210:00
MAD
-
SCL
2 stops25h 40m
Delta
Mon 2/323:10
SCL
-
MAD
1 stop30h 05m
Delta
Deal found 26/1£604
Wed 29/412:30
MAD
-
SCL
Nonstop13h 20m
Iberia
Sun 17/510:40
SCL
-
MAD
Nonstop12h 40m
Iberia
Deal found 26/1£617
Fri 30/110:00
MAD
-
SCL
2 stops25h 40m
Delta
Sun 15/223:10
SCL
-
MAD
2 stops32h 20m
Delta
Deal found 26/1£617
Sun 1/210:00
MAD
-
SCL
2 stops25h 40m
Delta
Sun 8/223:10
SCL
-
MAD
2 stops38h 30m
Delta
Deal found 27/1£619
Tue 5/506:00
MAD
-
SCL
2 stops31h 15m
Delta
Tue 26/520:40
SCL
-
MAD
2 stops27h 40m
Delta
Deal found 26/1£621
Mon 2/210:00
MAD
-
SCL
2 stops25h 40m
Delta
Sun 15/223:10
SCL
-
MAD
2 stops38h 30m
Delta
Deal found 27/1£622
Thu 22/1011:50
MAD
-
SCL
1 stop28h 30m
British Airways
Sun 1/1113:05
SCL
-
MAD
1 stop18h 50m
British Airways
Deal found 26/1£623
Wed 4/1111:50
MAD
-
SCL
1 stop31h 35m
British Airways
Fri 13/1113:05
SCL
-
MAD
1 stop18h 50m
British Airways
Deal found 27/1£627
Best flights from Madrid to Santiago
Discover carefully curated flight deals from Madrid to Santiago that have cost, travel time, and stopovers in mind to ensure you get the best travel experience. Data last updated 28 January 2026.
Mon 13/414:35
MAD
-
SCL
2 stops46h 40m
Delta
Sun 26/420:40
SCL
-
MAD
1 stop33h 35m
Delta
Deal found 27/1£604
Thu 16/414:35
MAD
-
SCL
2 stops46h 40m
Delta
Wed 29/420:40
SCL
-
MAD
2 stops55h 15m
Delta
Deal found 27/1£604
Thu 16/412:45
MAD
-
SCL
1 stop24h 30m
Delta
Tue 28/420:40
SCL
-
MAD
2 stops31h 15m
Delta
Deal found 27/1£604
Tue 14/414:35
MAD
-
SCL
2 stops46h 40m
Delta
Wed 29/420:40
SCL
-
MAD
2 stops55h 15m
Delta
Deal found 27/1£604
Tue 14/414:35
MAD
-
SCL
2 stops46h 40m
Delta
Tue 28/420:40
SCL
-
MAD
2 stops31h 15m
Delta
Deal found 27/1£604
Wed 15/412:45
MAD
-
SCL
1 stop24h 30m
Delta
Wed 29/420:40
SCL
-
MAD
2 stops55h 15m
Delta
Deal found 27/1£604
Wed 15/412:45
MAD
-
SCL
1 stop24h 30m
Delta
Tue 28/420:40
SCL
-
MAD
2 stops31h 15m
Delta
Deal found 27/1£604
Mon 13/414:35
MAD
-
SCL
2 stops46h 40m
Delta
Tue 28/420:40
SCL
-
MAD
2 stops31h 15m
Delta
Deal found 27/1£604
Thu 16/412:45
MAD
-
SCL
1 stop24h 30m
Delta
Mon 27/420:40
SCL
-
MAD
2 stops31h 15m
Delta
Deal found 27/1£648
Direct flights from Madrid to Santiago
Explore direct flight options from Madrid to Santiago based on user searches, and compare prices and availability for your desired travel dates. Data last updated 28 January 2026.
Wed 29/412:30
MAD
-
SCL
Nonstop13h 20m
Iberia
Sun 17/510:40
SCL
-
MAD
Nonstop12h 40m
Iberia
Deal found 26/1£617
Mon 9/312:55
MAD
-
SCL
Nonstop13h 20m
Iberia
Wed 25/313:05
SCL
-
MAD
Nonstop12h 35m
Iberia
Deal found 26/1£644
Mon 4/523:59
MAD
-
SCL
Nonstop13h 26m
Iberia
Sun 24/510:40
SCL
-
MAD
Nonstop12h 40m
Iberia
Deal found 27/1£646
Mon 9/312:55
MAD
-
SCL
Nonstop13h 20m
Iberia
Mon 23/323:55
SCL
-
MAD
Nonstop12h 40m
Iberia
Deal found 26/1£673
Thu 30/423:59
MAD
-
SCL
Nonstop13h 26m
Iberia
Fri 22/522:20
SCL
-
MAD
Nonstop12h 40m
Iberia
Deal found 26/1£727
Fri 13/312:55
MAD
-
SCL
Nonstop13h 20m
Iberia
Fri 20/313:05
SCL
-
MAD
Nonstop12h 35m
Iberia
Deal found 27/1£727
Mon 13/423:59
MAD
-
SCL
Nonstop13h 26m
Iberia
Sun 26/422:00
SCL
-
MAD
Nonstop12h 40m
Iberia
Deal found 27/1£738
Fri 17/413:20
MAD
-
SCL
Nonstop13h 20m
Iberia
Sun 26/422:00
SCL
-
MAD
Nonstop12h 40m
Iberia
Deal found 26/1£746
Fri 13/312:55
MAD
-
SCL
Nonstop13h 20m
Iberia
Wed 1/411:40
SCL
-
MAD
Nonstop12h 40m
Iberia
Deal found 26/1£748
Sun 12/413:00
MAD
-
SCL
Nonstop13h 20m
Iberia
Sun 26/422:00
SCL
-
MAD
Nonstop12h 40m
Iberia
Deal found 27/1£750
Tue 14/413:20
MAD
-
SCL
Nonstop13h 20m
Iberia
Sun 26/422:00
SCL
-
MAD
Nonstop12h 40m
Iberia
Deal found 27/1£751
Last-minute flights from Madrid to Santiago
Discover last-minute flight deals from Madrid to Santiago. Data last updated 28 January 2026 and is based on user searches.
Fri 30/110:00
MAD
-
SCL
2 stops25h 40m
Delta
Sun 15/223:10
SCL
-
MAD
2 stops32h 20m
Delta
Deal found 26/1£617
Fri 30/110:00
MAD
-
SCL
2 stops25h 40m
Delta
Mon 2/323:10
SCL
-
MAD
1 stop30h 05m
Delta
Deal found 27/1£642
Sat 31/110:00
MAD
-
SCL
2 stops25h 40m
Delta
Sat 14/223:10
SCL
-
MAD
2 stops31h 05m
Delta
Deal found 26/1£634
Sun 1/210:00
MAD
-
SCL
2 stops25h 40m
Delta
Sun 8/223:10
SCL
-
MAD
2 stops38h 30m
Delta
Deal found 27/1£619
Sun 1/210:00
MAD
-
SCL
2 stops25h 40m
Delta
Mon 23/223:10
SCL
-
MAD
2 stops36h 55m
Delta
Deal found 26/1£633
Mon 2/210:00
MAD
-
SCL
2 stops25h 40m
Delta
Sun 15/223:10
SCL
-
MAD
2 stops38h 30m
Delta
Deal found 27/1£622
Tue 3/211:15
MAD
-
SCL
1 stop24h 25m
Delta
Tue 24/223:10
SCL
-
MAD
1 stop30h 05m
Delta
Deal found 26/1£602
Tue 3/211:15
MAD
-
SCL
1 stop24h 25m
Delta
Tue 17/223:10
SCL
-
MAD
2 stops52h 50m
Delta
Deal found 26/1£603
Tue 3/210:00
MAD
-
SCL
2 stops25h 40m
Delta
Mon 16/223:10
SCL
-
MAD
2 stops28h 50m
Delta
Deal found 27/1£604
Tue 3/211:15
MAD
-
SCL
2 stops49h 35m
United Airlines
Thu 19/222:45
SCL
-
MAD
2 stops30h 30m
United Airlines
Deal found 26/1£638
Sat 7/211:15
MAD
-
SCL
1 stop24h 25m
Delta
Sun 1/323:10
SCL
-
MAD
2 stops28h 50m
Delta
Deal found 26/1£604
One-way flights from Madrid to Santiago
Search for one-way flight options from Madrid to Santiago. Find affordable one-way fares based on user searches. Data last updated 28 January 2026.
Tue 7/423:59
MAD
-
SCL
Nonstop13h 26m
Iberia
Deal found 27/1£395
Mon 9/312:55
MAD
-
SCL
Nonstop13h 20m
Iberia
Deal found 27/1£397
Sun 24/520:45
MAD
-
SCL
2 stops31h 45m
Multiple Airlines
Deal found 26/1£399
Tue 3/316:20
MAD
-
SCL
1 stop27h 00m
Avianca
Deal found 27/1£421
Tue 3/311:15
MAD
-
SCL
2 stops25h 35m
United Airlines
Deal found 25/1£429
Fri 6/211:15
MAD
-
SCL
2 stops49h 35m
United Airlines
Deal found 26/1£433
Tue 10/211:15
MAD
-
SCL
2 stops49h 35m
United Airlines
Deal found 25/1£434
Tue 7/423:45
MAD
-
SCL
2 stops19h 10m
LATAM Airlines
Deal found 27/1£437
Find flight deals from Madrid to Santiago
Discover tips and strategies to find the most affordable flight options for your journey from Madrid (MAD) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 28 January 2026.
Customise your flight search to find flights from Madrid to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 28 January 2026.
Use the filters below to find and compare flights from Madrid to Santiago that are best for you.
Fly from
Madrid
Fly to
Santiago
Route
Depart
Return
Price
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Mon 13/4
14:35-07:15
2 stops46h 40m
Santiago Arturo Merino Benitez
Sun 26/4
20:40-12:15
1 stop33h 35m
£604
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Thu 16/4
14:35-07:15
2 stops46h 40m
Santiago Arturo Merino Benitez
Wed 29/4
20:40-09:55
2 stops55h 15m
£604
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Thu 16/4
12:45-07:15
1 stop24h 30m
Santiago Arturo Merino Benitez
Tue 28/4
20:40-09:55
2 stops31h 15m
£604
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Tue 14/4
14:35-07:15
2 stops46h 40m
Santiago Arturo Merino Benitez
Wed 29/4
20:40-09:55
2 stops55h 15m
£604
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Tue 14/4
14:35-07:15
2 stops46h 40m
Santiago Arturo Merino Benitez
Tue 28/4
20:40-09:55
2 stops31h 15m
£604
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Wed 15/4
12:45-07:15
1 stop24h 30m
Santiago Arturo Merino Benitez
Wed 29/4
20:40-09:55
2 stops55h 15m
£604
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Wed 15/4
12:45-07:15
1 stop24h 30m
Santiago Arturo Merino Benitez
Tue 28/4
20:40-09:55
2 stops31h 15m
£604
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Mon 13/4
14:35-07:15
2 stops46h 40m
Santiago Arturo Merino Benitez
Tue 28/4
20:40-09:55
2 stops31h 15m
£604
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Thu 16/4
12:45-07:15
1 stop24h 30m
Santiago Arturo Merino Benitez
Mon 27/4
20:40-09:55
2 stops31h 15m
£648
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Wed 15/4
12:30-19:50
Nonstop13h 20m
£395
Flights are sorted by cheapest return flights first.
Deals found on 27/1
Showing 1-10 of 20 results
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Best time to book a flight from Madrid to Santiago
Have a flexible travel schedule? Discover the best time to fly to Santiago from Madrid with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Madrid to Santiago
Prices
Airlines
Delays
How far ahead should I book a flight from Madrid to Santiago?
Use this chart to determine the optimal time to book a return flight from Madrid to Santiago. Price data was last updated on 23 January 2026.
The price you pay for your flight from Madrid to Santiago may vary depending on when you book. For the best chance of a lower fare, look to book 72 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Madrid to Santiago?
Currently, March is the cheapest month in which you can book a flight from Madrid to Santiago (average of £376). Flying from Madrid to Santiago in July is currently the most expensive (average of £697). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MAD to SCL?
Find hourly flight availability from Madrid to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 28 January 2026.
A simple way to save on the total cost of your ticket is to fly from Madrid to Santiago in the morning. If you’re flexible enough to do this you can expect to save up to 11% on your trip compared to booking a flight in the afternoon.
How much does it cost for a return flight from Madrid to Santiago?
Weekly flight availability from Madrid to Santiago
Explore weekly flight availability from Madrid to Santiago. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated 28 January 2026.
The most flights from MAD to SCL are scheduled on a Monday (17 on average). You will have fewer flight options on Thursday, which is when the least amount of flights are scheduled (7 on average).
How often are flights from Madrid to Santiago delayed?
About 12% of weekly flights between Madrid and Santiago have experienced delays in the past year, with the average delay time being 132 minutes.
What is the most punctual flight time for Madrid to Santiago flights?
Historically, flights departing at night are less likely to be delayed, whereas flights leaving in the early afternoon tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Thursday tends to have the lowest number of delays on this route, whereas Sunday has historically faced a higher average of delays compared to other days of the week.
Which airline has the best punctuality record on Madrid to Santiago flights?
Over the past year, LATAM Airlines have had the lowest number of delays on this route, with just 9% of flights being delayed.
Reviews of airlines servicing Santiago
Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated 28 January 2026.
Read through reviews of airlines operating flights from Madrid to Santiago, such as LATAM Airlines, Iberia, andBritish Airways. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Plane was late in FLN and missed connection in GRU. No alternative was given to me until 6 hours later and I was delayed by over 12 hours total.
Related info for your journey
Find useful and relevant information for your journey from Madrid to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
What airports do I use to fly from Madrid to Santiago?
To fly from Madrid to Santiago, you need to book a flight from Barajas (MAD) to Arturo Merino Benitez (SCL). Nonstop flights to Santiago Arturo Merino Benitez from Madrid Barajas take 13h 15m on average. When it comes time to book airfare, you have a few options: there are 12 outbound flights from Barajas to Arturo Merino Benitez offered by 3 different airlines.
How popular is this Madrid to Santiago flight route?
This flight path from Madrid Barajas to Santiago Arturo Merino Benitez was viewed by 17 users in the past month. Keep an eye out for changes in search interest prior to high and low season.
How long is the flight from Madrid to Santiago?
A quick flight from Madrid to Santiago can take about 46h 40m. Delta provides one of the quickest options available for as low as £604. Airlines will cover a distance of 6656 mi.
What are the cheapest airlines flying from Madrid to Santiago round-trip?
Cheapflights users have booked flights from Madrid to Santiago round-trip from £504. Other airlines that can offer you cheap pricing are Iberia, from £625, and LATAM Airlines, from £733. Users have found that British Airways is 37% cheaper than the other options available to this destination.
What are the most reliable airlines from Madrid to Santiago?
No one likes to see their flight delayed. When booking a flight from Madrid to Santiago consider choosing Japan Airlines (88%), Finnair (88%) or EL AL (88%) as they are the most reliable in getting you off to your destination on time.
What are the cheapest flights from Madrid to Santiago?
Looking at all options, your cheapest flight can be booked for £416. While the most popular route (Madrid Barajas - Santiago Arturo Merino Benitez) can be booked for £716 on average, our data indicates £1,099 when flying from Madrid to Santiago.
Can I find deals for business class flights from Madrid to Santiago?
Yes. Cheapflights offers flight deals from Madrid to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Madrid to Santiago?
Currently, March is the cheapest month in which you can book a flight from Madrid to Santiago (average of £376). Flying from Madrid to Santiago in July is currently the most expensive (average of £697). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Explore flights to Santiago departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on 28 January 2026.
Discover the top 3 airlines that operate flights from Madrid to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 28 January 2026.
Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.
How does Cheapflights help users find flights from Madrid to Santiago?
Cheapflights makes it easy to find Madrid to Santiago flights by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.
Why should you use Cheapflights to find cheap flight tickets from Madrid to Santiago?
Millions of users choose and trust Cheapflights to book the best flight deals from Madrid to Santiago for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.
Can Cheapflights find flights from Madrid to Santiago with no change fees?
Certainly. Search results for flights to Santiago from Madrid shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.
Can Cheapflights notify me if prices for flights from Madrid to Santiago become cheaper?
Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!
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