Cheap flights from Madrid, Spain to Santiago from £278
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 15/5. Fares are subject to change and may not be available on all flights or dates of travel.
MAD — SCL
31 May — 7 Jun1
Return
1 adult
Economy
Return
1 adult, Economy, 0 bags
Cheapflights Tip: The best prices from Madrid Barajas to Santiago Arturo Merino Benitez are usually found in March or May, booked 72 days in advance, depart on a Monday or Sunday and return on a Wednesday
Cheap flight deals from Madrid to Santiago
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Cheapest flights from Madrid to Santiago
Explore the most affordable flight options available from Madrid to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 1 May 2026.
Wed 9/909:50
MAD
-
SCL
1 stop27h 25m
Delta
Fri 16/1020:40
SCL
-
MAD
1 stop34h 35m
Delta
Deal found 27/4£642
Tue 1/909:50
MAD
-
SCL
1 stop27h 25m
Delta
Tue 1/1223:10
SCL
-
MAD
1 stop30h 45m
Delta
Deal found 28/4£643
Mon 1/613:20
MAD
-
SCL
Nonstop13h 20m
Iberia
Sun 14/610:40
SCL
-
MAD
Nonstop12h 40m
Iberia
Deal found 1/5£646
Sun 17/513:00
MAD
-
SCL
Nonstop13h 20m
Iberia
Tue 2/610:40
SCL
-
MAD
Nonstop12h 40m
Iberia
Deal found 29/4£647
Thu 5/1113:05
MAD
-
SCL
2 stops46h 35m
Delta
Mon 23/1123:10
SCL
-
MAD
2 stops40h 00m
Delta
Deal found 28/4£647
Tue 3/1110:00
MAD
-
SCL
2 stops49h 40m
Delta
Wed 11/1123:10
SCL
-
MAD
2 stops28h 50m
Delta
Deal found 30/4£650
Thu 5/1111:55
MAD
-
SCL
1 stop23h 45m
Delta
Mon 16/1123:10
SCL
-
MAD
2 stops28h 50m
Delta
Deal found 29/4£650
Tue 6/1012:45
MAD
-
SCL
2 stops48h 30m
Delta
Wed 21/1020:40
SCL
-
MAD
2 stops32h 15m
Delta
Deal found 26/4£651
Wed 11/1110:00
MAD
-
SCL
2 stops25h 40m
Delta
Tue 1/1223:10
SCL
-
MAD
2 stops28h 50m
Delta
Deal found 28/4£652
Mon 18/512:25
MAD
-
SCL
2 stops24h 50m
Delta
Wed 3/620:40
SCL
-
MAD
2 stops30h 50m
Delta
Deal found 29/4£654
Best flights from Madrid to Santiago
Discover carefully curated flight deals from Madrid to Santiago that have cost, travel time, and stopovers in mind to ensure you get the best travel experience. Data last updated 1 May 2026.
Wed 27/507:40
MAD
-
SCL
2 stops41h 43m
Multiple Airlines
Tue 2/602:22
SCL
-
MAD
2 stops50h 03m
Multiple Airlines
Deal found 30/4£672
Tue 26/513:20
MAD
-
SCL
Nonstop13h 20m
Iberia
Tue 2/610:40
SCL
-
MAD
Nonstop12h 40m
Iberia
Deal found 28/4£674
Thu 10/910:25
MAD
-
SCL
2 stops26h 50m
Delta
Sun 18/1020:40
SCL
-
MAD
2 stops32h 15m
Delta
Deal found 30/4£718
Thu 11/618:25
MAD
-
SCL
2 stops44h 05m
Turkish Airlines
Mon 15/610:15
SCL
-
MAD
2 stops42h 10m
Turkish Airlines
Deal found 30/4£737
Tue 26/518:25
MAD
-
SCL
2 stops59h 01m
Multiple Airlines
Wed 3/611:17
SCL
-
MAD
2 stops41h 08m
Multiple Airlines
Deal found 29/4£676
Wed 27/509:50
MAD
-
SCL
1 stop27h 25m
Delta
Wed 3/620:40
SCL
-
MAD
2 stops30h 50m
Delta
Deal found 30/4£725
Mon 1/607:40
MAD
-
SCL
2 stops41h 43m
Multiple Airlines
Sun 14/610:15
SCL
-
MAD
2 stops42h 10m
Multiple Airlines
Deal found 28/4£735
Wed 3/614:40
MAD
-
SCL
3 stops44h 23m
Multiple Airlines
Sat 27/604:09
SCL
-
MAD
2 stops48h 16m
Multiple Airlines
Deal found 27/4£743
Mon 18/507:40
MAD
-
SCL
2 stops48h 40m
Multiple Airlines
Tue 26/511:17
SCL
-
MAD
2 stops29h 18m
Multiple Airlines
Deal found 26/4£761
Direct flights from Madrid to Santiago
Explore direct flight options from Madrid to Santiago based on user searches, and compare prices and availability for your desired travel dates. Data last updated 1 May 2026.
Mon 1/613:20
MAD
-
SCL
Nonstop13h 20m
Iberia
Sun 14/610:40
SCL
-
MAD
Nonstop12h 40m
Iberia
Deal found 1/5£646
Sun 17/513:00
MAD
-
SCL
Nonstop13h 20m
Iberia
Tue 2/610:40
SCL
-
MAD
Nonstop12h 40m
Iberia
Deal found 29/4£647
Wed 27/513:20
MAD
-
SCL
Nonstop13h 20m
Iberia
Fri 26/610:40
SCL
-
MAD
Nonstop12h 40m
Iberia
Deal found 30/4£672
Mon 18/523:59
MAD
-
SCL
Nonstop13h 26m
Iberia
Sun 14/610:40
SCL
-
MAD
Nonstop12h 40m
Iberia
Deal found 27/4£673
Tue 26/513:20
MAD
-
SCL
Nonstop13h 20m
Iberia
Tue 2/610:40
SCL
-
MAD
Nonstop12h 40m
Iberia
Deal found 28/4£674
Mon 1/623:59
MAD
-
SCL
Nonstop13h 26m
Iberia
Fri 12/610:40
SCL
-
MAD
Nonstop12h 40m
Iberia
Deal found 27/4£699
Tue 26/523:59
MAD
-
SCL
Nonstop13h 26m
Iberia
Wed 3/610:40
SCL
-
MAD
Nonstop12h 40m
Iberia
Deal found 26/4£729
Wed 27/523:55
MAD
-
SCL
Nonstop13h 05m
LATAM Airlines
Wed 3/619:00
SCL
-
MAD
Nonstop12h 55m
LATAM Airlines
Deal found 27/4£771
Sun 21/613:00
MAD
-
SCL
Nonstop13h 20m
Iberia
Sun 16/822:00
SCL
-
MAD
Nonstop12h 40m
Iberia
Deal found 1/5£791
Thu 11/623:59
MAD
-
SCL
Nonstop13h 26m
Iberia
Fri 7/822:20
SCL
-
MAD
Nonstop12h 40m
Iberia
Deal found 30/4£792
Last-minute flights from Madrid to Santiago
Discover last-minute flight deals from Madrid to Santiago. Data last updated 1 May 2026 and is based on user searches.
Sat 2/512:45
MAD
-
SCL
1 stop24h 30m
Delta
Mon 18/520:40
SCL
-
MAD
2 stops27h 40m
Delta
Deal found 30/4£650
Sat 2/512:45
MAD
-
SCL
1 stop24h 30m
Delta
Sun 3/520:40
SCL
-
MAD
2 stops31h 15m
Delta
Deal found 28/4£661
Tue 5/512:45
MAD
-
SCL
1 stop24h 30m
Delta
Sun 10/520:40
SCL
-
MAD
2 stops31h 15m
Delta
Deal found 27/4£660
Wed 6/512:45
MAD
-
SCL
1 stop24h 30m
Delta
Sat 23/520:40
SCL
-
MAD
2 stops51h 40m
Delta
Deal found 26/4£651
Sat 9/509:50
MAD
-
SCL
1 stop27h 25m
Delta
Sun 31/520:40
SCL
-
MAD
2 stops27h 40m
Delta
Deal found 28/4£652
Sun 17/513:00
MAD
-
SCL
Nonstop13h 20m
Iberia
Tue 2/610:40
SCL
-
MAD
Nonstop12h 40m
Iberia
Deal found 29/4£647
Mon 18/512:25
MAD
-
SCL
2 stops24h 50m
Delta
Wed 3/620:40
SCL
-
MAD
2 stops30h 50m
Delta
Deal found 29/4£654
Tue 26/513:20
MAD
-
SCL
Nonstop13h 20m
Iberia
Wed 3/610:40
SCL
-
MAD
Nonstop12h 40m
Iberia
Deal found 30/4£646
Wed 27/507:40
MAD
-
SCL
2 stops41h 43m
Multiple Airlines
Tue 2/602:22
SCL
-
MAD
2 stops50h 03m
Multiple Airlines
Deal found 30/4£672
One-way flights from Madrid to Santiago
Search for one-way flight options from Madrid to Santiago. Find affordable one-way fares based on user searches. Data last updated 1 May 2026.
Fri 15/513:15
MAD
-
SCL
Nonstop13h 20m
LATAM Airlines
Deal found 28/4£278
Thu 7/513:15
MAD
-
SCL
Nonstop13h 20m
LATAM Airlines
Deal found 29/4£325
Sun 17/521:10
MAD
-
SCL
2 stops41h 35m
Multiple Airlines
Deal found 27/4£341
Thu 14/500:10
MAD
-
SCL
2 stops38h 35m
Multiple Airlines
Deal found 28/4£364
Wed 6/510:55
MAD
-
SCL
2 stops29h 35m
Multiple Airlines
Deal found 27/4£366
Sun 17/523:59
MAD
-
SCL
Nonstop13h 26m
Iberia
Deal found 27/4£367
Fri 8/510:55
MAD
-
SCL
3 stops50h 16m
Multiple Airlines
Deal found 29/4£379
Find flight deals from Madrid to Santiago
Discover tips and strategies to find the most affordable flight options for your journey from Madrid (MAD) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 1 May 2026.
Customise your flight search to find flights from Madrid to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 1 May 2026.
Use the filters below to find and compare flights from Madrid to Santiago that are best for you.
Fly from
Fly to
Route
Depart
Return
Price
Cheapest return flight
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Wed 27/5
07:40-19:23
2 stops41h 43m
Santiago Arturo Merino Benitez
Tue 2/6
02:22-10:25
2 stops50h 03m
£672
Fastest return journey
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Tue 26/5
13:20-20:40
Nonstop13h 20m
Santiago Arturo Merino Benitez
Tue 2/6
10:40-05:20
Nonstop12h 40m
£674
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Tue 26/5
18:25-23:26
2 stops59h 01m
Santiago Arturo Merino Benitez
Wed 3/6
11:17-10:25
2 stops41h 08m
£676
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Thu 10/9
10:25-08:15
2 stops26h 50m
Santiago Arturo Merino Benitez
Sun 18/10
20:40-09:55
2 stops32h 15m
£718
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Wed 27/5
09:50-07:15
1 stop27h 25m
Santiago Arturo Merino Benitez
Wed 3/6
20:40-09:30
2 stops30h 50m
£725
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Mon 1/6
07:40-19:23
2 stops41h 43m
Santiago Arturo Merino Benitez
Sun 14/6
10:15-10:25
2 stops42h 10m
£735
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Thu 11/6
18:25-08:30
2 stops44h 05m
Santiago Arturo Merino Benitez
Mon 15/6
10:15-10:25
2 stops42h 10m
£737
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Wed 3/6
14:40-05:03
3 stops44h 23m
Santiago Arturo Merino Benitez
Sat 27/6
04:09-10:25
2 stops48h 16m
£743
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Mon 18/5
07:40-02:20
2 stops48h 40m
Santiago Arturo Merino Benitez
Tue 26/5
11:17-22:35
2 stops29h 18m
£761
Cheapest one-way
Fastest single journey
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Wed 20/5
13:20-20:40
Nonstop13h 20m
£368
Flights are sorted by cheapest return flights first.
Deals found on 30/4
Showing 1-10 of 19 resultsSorted by cheapest first
1
2
Best time to book a flight from Madrid to Santiago
Have a flexible travel schedule? Discover the best time to fly to Santiago from Madrid with our price prediction graph.
MAD-SCL
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Madrid to Santiago
Prices
Airlines
Delays
How far ahead should I book a flight from Madrid to Santiago?
The price you pay for your flight from Madrid to Santiago may vary depending on when you book. For the best chance of a lower fare, look to book 71 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Madrid to Santiago?
Currently, March is the cheapest month in which you can book a flight from Madrid to Santiago (average of £698). Flying from Madrid to Santiago in July is currently the most expensive (average of £1,047). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MAD to SCL?
Find hourly flight availability from Madrid to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 1 May 2026.
When flying from Madrid to Santiago, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
How much does it cost for a return flight from Madrid to Santiago?
Weekly flight availability from Madrid to Santiago
Explore weekly flight availability from Madrid to Santiago. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated 1 May 2026.
The most flights from MAD to SCL are scheduled on a Thursday (13 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (7 on average).
How often are flights from Madrid to Santiago delayed?
About 15% of weekly flights between Madrid and Santiago have experienced delays in the past year, with the average delay time being 132 minutes.
What is the most punctual flight time for Madrid to Santiago flights?
Historically, flights departing at night are less likely to be delayed, whereas flights leaving in the early afternoon tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Saturday tends to have the lowest number of delays on this route, whereas Friday has historically faced a higher average of delays compared to other days of the week.
Which airline has the best punctuality record on Madrid to Santiago flights?
Over the past year, LATAM Airlines have had the lowest number of delays on this route, with just 12% of flights being delayed.
Reviews of airlines servicing Santiago
Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated 1 May 2026.
Read through reviews of airlines operating flights from Madrid to Santiago, such as LATAM Airlines and Iberia. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Very old aircraft and it was very dirty in the seats and floor
Related info for your journey
Find useful and relevant information for your journey from Madrid to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
What airports do I use to fly from Madrid to Santiago?
To fly from Madrid to Santiago, you need to book a flight from Barajas (MAD) to Arturo Merino Benitez (SCL). Nonstop flights to Santiago Arturo Merino Benitez from Madrid Barajas take 13h 20m on average. When it comes time to book airfare, you have a few options: there are 9 outbound flights from Barajas to Arturo Merino Benitez offered by 2 different airlines.
How popular is this Madrid to Santiago flight route?
This flight path from Madrid Barajas to Santiago Arturo Merino Benitez was viewed by 18 users in the past month. Keep an eye out for changes in search interest prior to high and low season.
How long is the flight from Madrid to Santiago?
A quick flight from Madrid to Santiago can take about 13h 20m. Iberia provides one of the quickest options available for as low as £674. Airlines will cover a distance of 6656 mi. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.
What are the cheapest airlines flying from Madrid to Santiago round-trip?
Cheapflights users have booked flights from Madrid to Santiago round-trip from £600. Another airline that can offer you cheap pricing is LATAM Airlines. Users have found that Iberia is 27% cheaper than the other options available to this destination.
What are the most reliable airlines from Madrid to Santiago?
No one likes to see their flight delayed. When booking a flight from Madrid to Santiago consider choosing Japan Airlines (93%), EL AL (93%) or Finnair (89%) as they are the most reliable in getting you off to your destination on time.
What are the cheapest flights from Madrid to Santiago?
Looking at all options, your cheapest flight can be booked for £550. While the most popular route (Madrid Barajas - Santiago Arturo Merino Benitez) can be booked for £704 on average, our data indicates £890 when flying from Madrid to Santiago.
Can I find deals for business class flights from Madrid to Santiago?
Yes. Cheapflights offers flight deals from Madrid to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Madrid to Santiago?
Currently, March is the cheapest month in which you can book a flight from Madrid to Santiago (average of £698). Flying from Madrid to Santiago in July is currently the most expensive (average of £1,047). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Discover the top 2 airlines that operate flights from Madrid to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 1 May 2026.
Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.
How does Cheapflights help users find flights from Madrid to Santiago?
Cheapflights makes it easy to find Madrid to Santiago flights by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.
Why should you use Cheapflights to find cheap flight tickets from Madrid to Santiago?
Millions of users choose and trust Cheapflights to book the best flight deals from Madrid to Santiago for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.
Can Cheapflights find flights from Madrid to Santiago with no change fees?
Certainly. Search results for flights to Santiago from Madrid shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.
Can Cheapflights notify me if prices for flights from Madrid to Santiago become cheaper?
Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!
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