Find flights
Deals
Airlines

£107+ Direct flights from Panama City

PTY — LHR
19 Nov — 26 Nov1
1 adult
1 adult, Economy, 0 bags

Find direct flights from Panama City within your budget

 

Fly to

Route

Depart

Return

Price

Cheapest return flight

Panama CityMedellín

PTY Panama City Tocumen Intl - MDE Medellín Jose Maria Cordova Intl

PTYMDE

Panama City Tocumen Intl

Thu 10/12

13:23-14:45

Nonstop1h 22m

Medellín Jose Maria Cordova Intl

Wed 31/12

00:00-00:00

Nonstop0h 00m

£110

Panama CityMedellín

PTY Panama City Tocumen Intl - MDE Medellín Jose Maria Cordova Intl

PTYMDE

Panama City Tocumen Intl

Tue 22/12

06:53-08:15

Nonstop1h 22m

Medellín Jose Maria Cordova Intl

Wed 31/12

00:00-00:00

Nonstop0h 00m

£110

Panama CityMedellín

PTY Panama City Tocumen Intl - MDE Medellín Jose Maria Cordova Intl

PTYMDE

Panama City Tocumen Intl

Thu 5/11

13:25-14:45

Nonstop1h 20m

Medellín Jose Maria Cordova Intl

Wed 31/12

00:00-00:00

Nonstop0h 00m

£110
Fastest return journey

Panama CityMedellín

PTY Panama City Tocumen Intl - MDE Medellín Jose Maria Cordova Intl

PTYMDE

Panama City Tocumen Intl

Sun 15/11

06:57-08:15

Nonstop1h 18m

Medellín Jose Maria Cordova Intl

Wed 31/12

00:00-00:00

Nonstop0h 00m

£110

Panama CityMedellín

PTY Panama City Tocumen Intl - MDE Medellín Jose Maria Cordova Intl

PTYMDE

Panama City Tocumen Intl

Sat 20/2

12:54-14:15

Nonstop1h 21m

Medellín Jose Maria Cordova Intl

Wed 31/12

00:00-00:00

Nonstop0h 00m

£110

Panama CityMedellín

PTY Panama City Tocumen Intl - MDE Medellín Jose Maria Cordova Intl

PTYMDE

Panama City Tocumen Intl

Sat 14/11

09:34-10:55

Nonstop1h 21m

Medellín Jose Maria Cordova Intl

Wed 31/12

00:00-00:00

Nonstop0h 00m

£110

Panama CityMedellín

PTY Panama City Tocumen Intl - MDE Medellín Jose Maria Cordova Intl

PTYMDE

Panama City Tocumen Intl

Sat 7/11

13:25-14:45

Nonstop1h 20m

Medellín Jose Maria Cordova Intl

Wed 31/12

00:00-00:00

Nonstop0h 00m

£110

Panama CityMedellín

PTY Panama City Tocumen Intl - MDE Medellín Jose Maria Cordova Intl

PTYMDE

Panama City Tocumen Intl

Mon 23/11

06:57-08:15

Nonstop1h 18m

Medellín Jose Maria Cordova Intl

Wed 31/12

00:00-00:00

Nonstop0h 00m

£110

Panama CityCali

PTY Panama City Tocumen Intl - CLO Cali Alfonso B. Aragon Intl

PTYCLO

Panama City Tocumen Intl

Fri 6/11

12:29-14:06

Nonstop1h 37m

Cali Alfonso B. Aragon Intl

Wed 31/12

00:00-00:00

Nonstop0h 00m

£124

Panama CityCali

PTY Panama City Tocumen Intl - CLO Cali Alfonso B. Aragon Intl

PTYCLO

Panama City Tocumen Intl

Tue 27/10

12:29-14:11

Nonstop1h 42m

Cali Alfonso B. Aragon Intl

Wed 31/12

00:00-00:00

Nonstop0h 00m

£124

Flights are sorted by cheapest return flights first.

Deals found on 18/10

Showing 1-10 of 60 resultsSorted by cheapest first
1
2
3
...
6

Best time to book a flight from Panama City

Have a flexible travel schedule? Discover the best time to fly from Panama City with our price prediction graph.
Estimated return price

Reviews of airlines flying non-stop to Panama City

Read through reviews of airlines serving Panama City, such as KLM and Turkish Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7.8
Good
1,591 reviews
Check prices

Boarding

7.8

Overall

7.8

Comfort

7.7

Crew

8.4

Entertainment

7.2

Food

7.4

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
KLM
7.8
Good
1,591 reviews
KLM
7.8
Good
1,591 reviews
Check prices

Boarding

7.8

Overall

7.8

Comfort

7.7

Crew

8.4

Entertainment

7.2

Food

7.4

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
Turkish Airlines
7.4
Good
4,457 reviews
KLM
7.8
Good
1,591 reviews
Check prices

Boarding

7.8

Overall

7.8

Comfort

7.7

Crew

8.4

Entertainment

7.2

Food

7.4

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas

Related info for your journey

  • Where can you fly direct from Panama City?

    Currently, the most popular direct flight destination from Panama City is Miami.

  • How much are direct flights from Panama City?

    On average, a one-way direct flight from Panama City will cost users approximately £327. If you're looking for a direct round-trip flight from Panama City, you can expect to pay around £665.

  • How long is a direct flight from Panama City?

    While the flight duration depends heavily on the destination, on average, travelers can expect non-stop flights from Panama City to last approximately 1h 49m on average. The quickest direct flight from Panama City at this time departs from Panama City (1h 18m), while the longest leaves from Panama City (2h 21m).

  • What is the best time of year to fly direct from Panama City?

    If you're seeking the lowest price on a direct flight from Panama City, March is worth consideration as prices are at their lowest, on average. In terms of the number of daily non-stop flights, July offers travelers the most options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Direct flights from cities

Direct flights from Panama City

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.