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£127+ Direct flights from Panama City

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 23/9. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
PTY — LHR
17 Oct — 24 Oct1
1 adult
1 adult, Economy

Direct flights from Panama City

Cheapest flights from Panama City
Explore the most affordable flight options available from Panama City. Find the lowest fares based on data from user searches, with prices last updated on 17 September 2025.

Fri 21/1111:36PTY - CUC
Nonstop1h 49mCopa Airlines
Thu 27/1112:14CUC - PTY
Nonstop1h 48mCopa Airlines
Deal found 15/9£239
Sat 1/1111:36PTY - CUC
Nonstop1h 49mCopa Airlines
Wed 5/1114:39CUC - PTY
Nonstop1h 46mCopa Airlines
Deal found 15/9£246
Sun 12/1009:20PTY - CUC
Nonstop1h 40mCopa Airlines
Sat 18/1012:11CUC - PTY
Nonstop1h 47mCopa Airlines
Deal found 16/9£265
Sat 27/1211:36PTY - CUC
Nonstop1h 49mCopa Airlines
Sun 28/1214:39CUC - PTY
Nonstop1h 46mCopa Airlines
Deal found 14/9£285
Fri 12/1211:36PTY - CUC
Nonstop1h 49mCopa Airlines
Sat 3/114:44CUC - PTY
Nonstop1h 41mCopa Airlines
Deal found 15/9£429
Wed 17/1211:36PTY - CUC
Nonstop1h 49mCopa Airlines
Sat 17/114:44CUC - PTY
Nonstop1h 41mCopa Airlines
Deal found 16/9£448
Fri 19/1211:36PTY - CUC
Nonstop1h 49mCopa Airlines
Mon 5/114:44CUC - PTY
Nonstop1h 41mCopa Airlines
Deal found 14/9£565
Sat 1/1109:20PTY - CUC
Nonstop1h 52mCopa Airlines
Sun 9/1112:20CUC - PTY
Nonstop1h 42mCopa Airlines
Deal found 16/9£935
Mon 1/1211:36PTY - CUC
Nonstop1h 49mCopa Airlines
Mon 5/114:44CUC - PTY
Nonstop1h 41mCopa Airlines
Deal found 15/9£1,411

Find direct flights from Panama City within your budget

 
Use the slider to find direct flights from Panama City within your budget. Price data is based on user searches made on Cheapflights. Over the past seven days, Cheapflights users made 858,174 searches. This data was last updated on 17 September 2025.

Fly to

Heathrow

Route

Depart

Return

Price

Panama CityCúcuta

PTY - CUC

PTYCUC

Panama City Tocumen Intl

Wed 19/11

11:36-13:23

Nonstop1h 47m

Cúcuta Camilo Dazo

Tue 25/11

12:20-14:02

Nonstop1h 42m

£239

Panama CityCúcuta

PTY - CUC

PTYCUC

Panama City Tocumen Intl

Sat 22/11

11:36-13:23

Nonstop1h 47m

Cúcuta Camilo Dazo

Fri 28/11

14:39-16:25

Nonstop1h 46m

£239

Panama CityCúcuta

PTY - CUC

PTYCUC

Panama City Tocumen Intl

Fri 21/11

11:36-13:25

Nonstop1h 49m

Cúcuta Camilo Dazo

Thu 27/11

12:14-14:02

Nonstop1h 48m

£239

Panama CityCúcuta

PTY - CUC

PTYCUC

Panama City Tocumen Intl

Mon 24/11

11:36-13:23

Nonstop1h 47m

Cúcuta Camilo Dazo

Mon 1/12

14:39-16:25

Nonstop1h 46m

£239

Panama CityCúcuta

PTY - CUC

PTYCUC

Panama City Tocumen Intl

Tue 30/12

11:36-13:25

Nonstop1h 49m

Cúcuta Camilo Dazo

Mon 2/2

14:42-16:25

Nonstop1h 43m

£239

Panama CityCúcuta

PTY - CUC

PTYCUC

Panama City Tocumen Intl

Tue 30/9

09:20-11:08

Nonstop1h 48m

Cúcuta Camilo Dazo

Sun 5/10

12:11-13:58

Nonstop1h 47m

£239

Panama CityCúcuta

PTY - CUC

PTYCUC

Panama City Tocumen Intl

Wed 15/10

09:20-11:00

Nonstop1h 40m

Cúcuta Camilo Dazo

Fri 17/10

12:11-13:58

Nonstop1h 47m

£239

Panama CityCúcuta

PTY - CUC

PTYCUC

Panama City Tocumen Intl

Sat 15/11

11:36-13:25

Nonstop1h 49m

Cúcuta Camilo Dazo

Fri 28/11

14:39-16:25

Nonstop1h 46m

£239

Panama CityCúcuta

PTY - CUC

PTYCUC

Panama City Tocumen Intl

Thu 16/10

09:20-11:00

Nonstop1h 40m

Cúcuta Camilo Dazo

Thu 30/10

12:15-14:02

Nonstop1h 47m

£239

Panama CityCúcuta

PTY - CUC

PTYCUC

Panama City Tocumen Intl

Tue 23/9

09:20-11:08

Nonstop1h 48m

£127

Flights are sorted by cheapest return flights first.

Deals found on 15/9

Showing 1-10 of 19 results
1
2

Best time to book a flight from Panama City

Have a flexible travel schedule? Discover the best time to fly from Panama City with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines flying non-stop to Panama City

Get insights into the airlines that provide direct flights from Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight from Panama City. Reviews last updated Cheapflights.
Read through reviews of airlines serving Panama City, such as KLM, Air France, andUnited Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7.8
Good
1,386 reviews
Check prices

Entertainment

7.2

Crew

8.4

Boarding

7.8

Food

7.3

Comfort

7.7

Overall

7.8

Reviews

1 / 20
4.0
Okay

Mark,Sept 2025

AMS - BHX

Crew and snacks were good, boarding wasn't great as busses were used rather than boarding tunnels. Also endured a one hour delay.
KLM
7.8
Good
1,386 reviews
KLM
7.8
Good
1,386 reviews
Check prices

Entertainment

7.2

Crew

8.4

Boarding

7.8

Food

7.3

Comfort

7.7

Overall

7.8

Reviews

1 / 20
4.0
Okay

Mark,Sept 2025

AMS - BHX

Crew and snacks were good, boarding wasn't great as busses were used rather than boarding tunnels. Also endured a one hour delay.
Air France
7.4
Good
1,468 reviews
KLM
7.8
Good
1,386 reviews
Check prices

Entertainment

7.2

Crew

8.4

Boarding

7.8

Food

7.3

Comfort

7.7

Overall

7.8

Reviews

1 / 20
4.0
Okay

Mark,Sept 2025

AMS - BHX

Crew and snacks were good, boarding wasn't great as busses were used rather than boarding tunnels. Also endured a one hour delay.
United Airlines
7.4
Good
8,924 reviews
KLM
7.8
Good
1,386 reviews
Check prices

Entertainment

7.2

Crew

8.4

Boarding

7.8

Food

7.3

Comfort

7.7

Overall

7.8

Reviews

1 / 20
4.0
Okay

Mark,Sept 2025

AMS - BHX

Crew and snacks were good, boarding wasn't great as busses were used rather than boarding tunnels. Also endured a one hour delay.

Related info for your journey

Access useful and relevant information related to your journey from Panama City. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 17 September 2025.

  • Where can you fly direct from Panama City?

    Currently, the most popular direct flight destination from Panama City is Madrid.

  • How much are direct flights from Panama City?

    On average, a one-way direct flight from Panama City will cost users approximately £411. If you're looking for a direct round-trip flight from Panama City, you can expect to pay around £432.

  • How long is a direct flight from Panama City?

    While the flight duration depends heavily on the destination, on average, travelers can expect non-stop flights from Panama City to last approximately 3h 28m on average. The quickest direct flight from Panama City at this time departs from Panama City (1h 14m), while the longest leaves from Panama City (10h 05m).

  • What is the best time of year to fly direct from Panama City?

    If you're seeking the lowest price on a direct flight from Panama City, May is worth consideration as prices are at their lowest, on average. In terms of the number of daily non-stop flights, July offers travelers the most options.

See more FAQs

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