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£92+ Direct flights from Santo Domingo

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 17/4. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
SDQ — LGW
3 Apr — 10 Apr1
1 adult
1 adult, Economy, 0 bags

Direct flights from Santo Domingo

Enter your travel dates to find the best prices.

Cheapest flights from Santo Domingo
Explore the most affordable flight options available from Santo Domingo. Find the lowest fares based on data from user searches, with prices last updated on 4 March 2026.

Sat 18/415:35
SDQ
-
MIA
Nonstop2h 20m
Arajet
Sat 25/419:25
MIA
-
SDQ
Nonstop2h 20m
Arajet
Deal found 4/3£155
Fri 24/410:19
SDQ
-
MIA
Nonstop2h 20m
Arajet
Mon 27/414:09
MIA
-
SDQ
Nonstop2h 20m
Arajet
Deal found 3/3£163
Thu 16/417:02
SDQ
-
MIA
Nonstop2h 20m
Arajet
Thu 23/420:52
MIA
-
SDQ
Nonstop2h 20m
Arajet
Deal found 2/3£184
Wed 1/410:19
SDQ
-
MIA
Nonstop2h 20m
Multiple Airlines
Wed 8/411:38
MIA
-
SDQ
Nonstop2h 18m
Multiple Airlines
Deal found 2/3£196
Sun 10/509:13
SDQ
-
CTG
Nonstop2h 02m
Arajet
Sun 17/511:00
CTG
-
SDQ
Nonstop2h 00m
Arajet
Deal found 3/3£241
Mon 27/410:19
SDQ
-
MIA
Nonstop2h 20m
WorldTicket
Thu 30/420:52
MIA
-
SDQ
Nonstop2h 20m
WorldTicket
Deal found 4/3£280
Tue 7/415:35
SDQ
-
MIA
Nonstop2h 20m
WorldTicket
Sat 11/419:25
MIA
-
SDQ
Nonstop2h 20m
WorldTicket
Deal found 3/3£280
Tue 5/516:00
SDQ
-
GUA
Nonstop3h 30m
WorldTicket
Tue 12/518:15
GUA
-
SDQ
Nonstop3h 34m
WorldTicket
Deal found 27/2£280
Thu 2/417:02
SDQ
-
MIA
Nonstop2h 20m
WorldTicket
Sat 11/419:25
MIA
-
SDQ
Nonstop2h 20m
WorldTicket
Deal found 3/3£294
Sat 9/515:35
SDQ
-
MIA
Nonstop2h 20m
WorldTicket
Mon 11/514:09
MIA
-
SDQ
Nonstop2h 20m
WorldTicket
Deal found 1/3£297
Tue 7/415:35
SDQ
-
MIA
Nonstop2h 20m
WorldTicket
Sun 12/419:25
MIA
-
SDQ
Nonstop2h 20m
WorldTicket
Deal found 3/3£298
Thu 19/315:35
SDQ
-
MIA
Nonstop2h 20m
WorldTicket
Sun 22/319:25
MIA
-
SDQ
Nonstop2h 20m
WorldTicket
Deal found 1/3£301

Find direct flights from Santo Domingo within your budget

 
Use the slider to find direct flights from Santo Domingo within your budget. Price data is based on user searches made on Cheapflights. Over the past seven days, Cheapflights users made 858,174 searches. This data was last updated on 4 March 2026.

Fly to

Route

Depart

Return

Price

Santo DomingoMiami

SDQ - MIA

SDQMIA

Santo Domingo Las Americas

Sat 18/4

15:35-17:55

Nonstop2h 20m

Miami

Sat 25/4

19:25-21:45

Nonstop2h 20m

£155

Santo DomingoMiami

SDQ - MIA

SDQMIA

Santo Domingo Las Americas

Wed 22/7

10:19-12:39

Nonstop2h 20m

Miami

Tue 11/8

19:25-21:45

Nonstop2h 20m

£163

Santo DomingoMiami

SDQ - MIA

SDQMIA

Santo Domingo Las Americas

Fri 24/4

10:19-12:39

Nonstop2h 20m

Miami

Mon 27/4

14:09-16:29

Nonstop2h 20m

£163

Santo DomingoMiami

SDQ - MIA

SDQMIA

Santo Domingo Las Americas

Wed 1/4

10:19-12:39

Nonstop2h 20m

Miami

Wed 8/4

11:38-13:56

Nonstop2h 18m

£196

Santo DomingoCartagena

SDQ - CTG

SDQCTG

Santo Domingo Las Americas

Sun 10/5

09:13-10:15

Nonstop2h 02m

Cartagena Rafael Nunez

Sun 17/5

11:00-14:00

Nonstop2h 00m

£241

Santo DomingoMiami

SDQ - MIA

SDQMIA

Santo Domingo Las Americas

Sat 9/5

15:35-17:55

Nonstop2h 20m

Miami

Mon 11/5

14:09-16:29

Nonstop2h 20m

£280

Santo DomingoGuatemala City

SDQ - GUA

SDQGUA

Santo Domingo Las Americas

Tue 5/5

16:00-17:30

Nonstop3h 30m

Guatemala City La Aurora

Tue 12/5

18:15-23:49

Nonstop3h 34m

£280

Santo DomingoGuatemala City

SDQ - GUA

SDQGUA

Santo Domingo Las Americas

Sat 16/5

16:00-17:30

Nonstop3h 30m

Guatemala City La Aurora

Sat 23/5

18:15-23:49

Nonstop3h 34m

£280

Santo DomingoMiami

SDQ - MIA

SDQMIA

Santo Domingo Las Americas

Sun 5/4

15:35-17:55

Nonstop2h 20m

Miami

Sat 11/4

19:25-21:45

Nonstop2h 20m

£294

Santo DomingoMiami

SDQ - MIA

SDQMIA

Santo Domingo Las Americas

Thu 19/3

15:35-17:55

Nonstop2h 20m

Miami

Sun 22/3

19:25-21:45

Nonstop2h 20m

£301

Flights are sorted by cheapest return flights first.

Deals found on 3/3

Showing 1-10 of 24 resultsSorted by cheapest first
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Best time to book a flight from Santo Domingo

Have a flexible travel schedule? Discover the best time to fly from Santo Domingo with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Access useful and relevant information related to your journey from Santo Domingo. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 4 March 2026.

  • Where can you fly direct from Santo Domingo?

    Currently, the most popular direct flight destination from Santo Domingo is Madrid.

  • How much are direct flights from Santo Domingo?

    On average, a one-way direct flight from Santo Domingo will cost users approximately £463. If you're looking for a direct round-trip flight from Santo Domingo, you can expect to pay around £696.

  • What is the best time of year to fly direct from Santo Domingo?

    If you're seeking the lowest price on a direct flight from Santo Domingo, October is worth consideration as prices are at their lowest, on average. In terms of the number of daily non-stop flights, January offers travelers the most options.

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