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£121+ Direct flights from Santo Domingo

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/2. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
SDQ — LGW
21 Feb — 28 Feb1
1 adult
1 adult, Economy, 0 bags

Direct flights from Santo Domingo

Enter your travel dates to find the best prices.

Cheapest flights from Santo Domingo
Explore the most affordable flight options available from Santo Domingo. Find the lowest fares based on data from user searches, with prices last updated on 22 January 2026.

Mon 23/310:19
SDQ
-
MIA
Nonstop2h 20m
Arajet
Mon 13/414:09
MIA
-
SDQ
Nonstop2h 20m
Arajet
Deal found 20/1£168
Tue 10/215:35
SDQ
-
MIA
Nonstop2h 20m
Arajet
Tue 17/218:25
MIA
-
SDQ
Nonstop2h 20m
Arajet
Deal found 20/1£179
Tue 31/316:00
SDQ
-
GUA
Nonstop3h 30m
Arajet
Mon 6/409:30
GUA
-
SDQ
Nonstop3h 34m
Arajet
Deal found 20/1£213
Fri 10/710:19
SDQ
-
MIA
Nonstop2h 20m
WorldTicket
Wed 15/714:09
MIA
-
SDQ
Nonstop2h 20m
WorldTicket
Deal found 19/1£274
Thu 9/406:10
SDQ
-
GUA
Nonstop3h 30m
WorldTicket
Tue 21/418:15
GUA
-
SDQ
Nonstop3h 34m
WorldTicket
Deal found 20/1£285
Tue 3/215:54
SDQ
-
GUA
Nonstop3h 36m
WorldTicket
Sat 21/218:15
GUA
-
SDQ
Nonstop3h 35m
WorldTicket
Deal found 20/1£296
Fri 10/710:19
SDQ
-
MIA
Nonstop2h 20m
WorldTicket
Thu 16/720:52
MIA
-
SDQ
Nonstop2h 20m
WorldTicket
Deal found 19/1£300
Tue 31/316:00
SDQ
-
GUA
Nonstop3h 30m
WorldTicket
Sat 4/418:15
GUA
-
SDQ
Nonstop3h 34m
WorldTicket
Deal found 20/1£302
Tue 17/215:54
SDQ
-
GUA
Nonstop3h 36m
WorldTicket
Thu 19/208:25
GUA
-
SDQ
Nonstop3h 35m
WorldTicket
Deal found 20/1£305
Mon 2/210:19
SDQ
-
MIA
Nonstop2h 20m
WorldTicket
Fri 6/213:09
MIA
-
SDQ
Nonstop2h 20m
WorldTicket
Deal found 20/1£309
Fri 6/318:00
SDQ
-
CTG
Nonstop2h 02m
WorldTicket
Fri 13/319:47
CTG
-
SDQ
Nonstop2h 00m
WorldTicket
Deal found 19/1£313
Mon 22/610:19
SDQ
-
MIA
Nonstop2h 20m
WorldTicket
Thu 2/720:52
MIA
-
SDQ
Nonstop2h 20m
WorldTicket
Deal found 20/1£319

Find direct flights from Santo Domingo within your budget

 
Use the slider to find direct flights from Santo Domingo within your budget. Price data is based on user searches made on Cheapflights. Over the past seven days, Cheapflights users made 858,174 searches. This data was last updated on 22 January 2026.

Fly to

Gatwick

Route

Depart

Return

Price

Santo DomingoMiami

SDQ - MIA

SDQMIA

Santo Domingo Las Americas

Mon 23/3

10:19-12:39

Nonstop2h 20m

Miami

Mon 13/4

14:09-16:29

Nonstop2h 20m

£168

Santo DomingoMiami

SDQ - MIA

SDQMIA

Santo Domingo Las Americas

Tue 10/2

15:35-16:55

Nonstop2h 20m

Miami

Tue 17/2

18:25-21:45

Nonstop2h 20m

£179

Santo DomingoGuatemala City

SDQ - GUA

SDQGUA

Santo Domingo Las Americas

Tue 31/3

16:00-17:30

Nonstop3h 30m

Guatemala City La Aurora

Mon 6/4

09:30-15:04

Nonstop3h 34m

£213

Santo DomingoMiami

SDQ - MIA

SDQMIA

Santo Domingo Las Americas

Fri 10/7

10:19-12:39

Nonstop2h 20m

Miami

Wed 15/7

14:09-16:29

Nonstop2h 20m

£274

Santo DomingoGuatemala City

SDQ - GUA

SDQGUA

Santo Domingo Las Americas

Thu 9/4

06:10-07:40

Nonstop3h 30m

Guatemala City La Aurora

Tue 21/4

18:15-23:49

Nonstop3h 34m

£285

Santo DomingoGuatemala City

SDQ - GUA

SDQGUA

Santo Domingo Las Americas

Tue 3/2

15:54-17:30

Nonstop3h 36m

Guatemala City La Aurora

Sat 21/2

18:15-23:50

Nonstop3h 35m

£296

Santo DomingoMiami

SDQ - MIA

SDQMIA

Santo Domingo Las Americas

Fri 10/7

10:19-12:39

Nonstop2h 20m

Miami

Thu 16/7

20:52-23:12

Nonstop2h 20m

£300

Santo DomingoGuatemala City

SDQ - GUA

SDQGUA

Santo Domingo Las Americas

Tue 31/3

16:00-17:30

Nonstop3h 30m

Guatemala City La Aurora

Sat 4/4

18:15-23:49

Nonstop3h 34m

£302

Santo DomingoGuatemala City

SDQ - GUA

SDQGUA

Santo Domingo Las Americas

Tue 17/2

15:54-17:30

Nonstop3h 36m

Guatemala City La Aurora

Thu 19/2

08:25-14:00

Nonstop3h 35m

£305

Santo DomingoMiami

SDQ - MIA

SDQMIA

Santo Domingo Las Americas

Mon 2/2

10:19-11:39

Nonstop2h 20m

Miami

Fri 6/2

13:09-16:29

Nonstop2h 20m

£309

Flights are sorted by cheapest return flights first.

Deals found on 19/1

Showing 1-10 of 28 results
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Best time to book a flight from Santo Domingo

Have a flexible travel schedule? Discover the best time to fly from Santo Domingo with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Access useful and relevant information related to your journey from Santo Domingo. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 22 January 2026.

  • Where can you fly direct from Santo Domingo?

    Currently, the most popular direct flight destination from Santo Domingo is Simpson Bay.

  • What is the best time of year to fly direct from Santo Domingo?

    If you're seeking the lowest price on a direct flight from Santo Domingo, June is worth consideration as prices are at their lowest, on average. In terms of the number of daily non-stop flights, September offers travelers the most options.

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