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£125+ Direct flights from Santo Domingo

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/3. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
SDQ — LGW
28 Mar — 4 Apr1
1 adult
1 adult, Economy, 0 bags

Direct flights from Santo Domingo

Enter your travel dates to find the best prices.

Cheapest flights from Santo Domingo
Explore the most affordable flight options available from Santo Domingo. Find the lowest fares based on data from user searches, with prices last updated on 26 February 2026.

Wed 15/410:19
SDQ
-
MIA
Nonstop2h 20m
Arajet
Thu 23/420:52
MIA
-
SDQ
Nonstop2h 20m
Arajet
Deal found 24/2£156
Sat 23/515:35
SDQ
-
MIA
Nonstop2h 20m
WorldTicket
Fri 29/514:09
MIA
-
SDQ
Nonstop2h 20m
WorldTicket
Deal found 24/2£276
Tue 31/315:35
SDQ
-
MIA
Nonstop2h 20m
WorldTicket
Thu 2/420:52
MIA
-
SDQ
Nonstop2h 20m
WorldTicket
Deal found 24/2£276
Fri 10/410:19
SDQ
-
MIA
Nonstop2h 20m
WorldTicket
Fri 17/414:09
MIA
-
SDQ
Nonstop2h 20m
WorldTicket
Deal found 24/2£278
Sat 23/515:35
SDQ
-
MIA
Nonstop2h 20m
WorldTicket
Tue 2/619:25
MIA
-
SDQ
Nonstop2h 20m
WorldTicket
Deal found 24/2£279
Fri 13/310:19
SDQ
-
MIA
Nonstop2h 20m
WorldTicket
Tue 24/319:25
MIA
-
SDQ
Nonstop2h 20m
WorldTicket
Deal found 23/2£290
Sat 9/515:35
SDQ
-
MIA
Nonstop2h 20m
WorldTicket
Mon 11/514:09
MIA
-
SDQ
Nonstop2h 20m
WorldTicket
Deal found 23/2£293
Fri 13/310:19
SDQ
-
MIA
Nonstop2h 20m
WorldTicket
Mon 30/314:09
MIA
-
SDQ
Nonstop2h 20m
WorldTicket
Deal found 25/2£294
Sun 15/315:35
SDQ
-
MIA
Nonstop2h 20m
WorldTicket
Sat 21/319:25
MIA
-
SDQ
Nonstop2h 20m
WorldTicket
Deal found 24/2£294
Thu 20/806:10
SDQ
-
GUA
Nonstop3h 30m
WorldTicket
Sat 22/818:15
GUA
-
SDQ
Nonstop3h 34m
WorldTicket
Deal found 23/2£311
Thu 12/306:04
SDQ
-
GUA
Nonstop3h 36m
WorldTicket
Tue 28/418:15
GUA
-
SDQ
Nonstop3h 34m
WorldTicket
Deal found 26/2£326
Mon 30/307:15
SDQ
-
GUA
Nonstop3h 30m
WorldTicket
Sat 4/418:15
GUA
-
SDQ
Nonstop3h 34m
WorldTicket
Deal found 24/2£330

Find direct flights from Santo Domingo within your budget

 
Use the slider to find direct flights from Santo Domingo within your budget. Price data is based on user searches made on Cheapflights. Over the past seven days, Cheapflights users made 858,174 searches. This data was last updated on 26 February 2026.

Fly to

Route

Depart

Return

Price

Santo DomingoMiami

SDQ - MIA

SDQMIA

Santo Domingo Las Americas

Sun 24/5

15:35-17:55

Nonstop2h 20m

Miami

Thu 28/5

20:52-23:12

Nonstop2h 20m

£276

Santo DomingoMiami

SDQ - MIA

SDQMIA

Santo Domingo Las Americas

Tue 31/3

15:35-17:55

Nonstop2h 20m

Miami

Thu 2/4

20:52-23:12

Nonstop2h 20m

£276

Santo DomingoMiami

SDQ - MIA

SDQMIA

Santo Domingo Las Americas

Fri 10/4

10:19-12:39

Nonstop2h 20m

Miami

Fri 17/4

14:09-16:29

Nonstop2h 20m

£278

Santo DomingoMiami

SDQ - MIA

SDQMIA

Santo Domingo Las Americas

Wed 27/5

10:19-12:39

Nonstop2h 20m

Miami

Sun 31/5

19:25-21:45

Nonstop2h 20m

£279

Santo DomingoMiami

SDQ - MIA

SDQMIA

Santo Domingo Las Americas

Sat 23/5

15:35-17:55

Nonstop2h 20m

Miami

Sun 31/5

19:25-21:45

Nonstop2h 20m

£279

Santo DomingoMiami

SDQ - MIA

SDQMIA

Santo Domingo Las Americas

Fri 13/3

10:19-12:39

Nonstop2h 20m

Miami

Tue 24/3

19:25-21:45

Nonstop2h 20m

£290

Santo DomingoMiami

SDQ - MIA

SDQMIA

Santo Domingo Las Americas

Sat 9/5

15:35-17:55

Nonstop2h 20m

Miami

Mon 11/5

14:09-16:29

Nonstop2h 20m

£293

Santo DomingoMiami

SDQ - MIA

SDQMIA

Santo Domingo Las Americas

Sun 15/3

15:35-17:55

Nonstop2h 20m

Miami

Sat 21/3

19:25-21:45

Nonstop2h 20m

£294

Santo DomingoMiami

SDQ - MIA

SDQMIA

Santo Domingo Las Americas

Fri 13/3

10:19-12:39

Nonstop2h 20m

Miami

Mon 30/3

14:09-16:29

Nonstop2h 20m

£295

Santo DomingoGuatemala City

SDQ - GUA

SDQGUA

Santo Domingo Las Americas

Thu 20/8

06:10-07:40

Nonstop3h 30m

Guatemala City La Aurora

Sat 22/8

18:15-23:49

Nonstop3h 34m

£311

Flights are sorted by cheapest return flights first.

Deals found on 25/2

Showing 1-10 of 27 resultsSorted by cheapest first
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Best time to book a flight from Santo Domingo

Have a flexible travel schedule? Discover the best time to fly from Santo Domingo with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Access useful and relevant information related to your journey from Santo Domingo. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 26 February 2026.

  • Where can you fly direct from Santo Domingo?

    Currently, the most popular direct flight destination from Santo Domingo is Madrid.

  • How much are direct flights from Santo Domingo?

    On average, a one-way direct flight from Santo Domingo will cost users approximately £343. If you're looking for a direct round-trip flight from Santo Domingo, you can expect to pay around £687.

  • What is the best time of year to fly direct from Santo Domingo?

    If you're seeking the lowest price on a direct flight from Santo Domingo, October is worth consideration as prices are at their lowest, on average. In terms of the number of daily non-stop flights, January offers travelers the most options.

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