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Cheap flights from Santo Domingo to Guatemala City from £160

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/2. Fares are subject to change and may not be available on all flights or dates of travel.
SDQ — GUA
7 Jan — 14 Jan1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Santo Domingo to Guatemala City

Enter your travel dates to find the best prices.

Cheapest flights from Santo Domingo to Guatemala City
Explore the most affordable flight options available from Santo Domingo to Guatemala City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 8 December 2025.

Thu 25/1204:07SDQ - GUA
1 stop13h 32mJetBlue
Fri 2/114:26GUA - SDQ
1 stop8h 36mJetBlue
Deal found 7/12£291
Sat 20/1205:01SDQ - GUA
1 stop10h 13mJetBlue
Sat 27/1216:41GUA - SDQ
1 stop15h 04mJetBlue
Deal found 8/12£313
Tue 30/1212:40SDQ - GUA
1 stop9h 15mCopa Airlines
Tue 6/113:15GUA - SDQ
1 stop7h 40mCopa Airlines
Deal found 6/12£355
Fri 26/1212:40SDQ - GUA
1 stop12h 07mCopa Airlines
Fri 2/106:24GUA - SDQ
2 stops9h 41mCopa Airlines
Deal found 6/12£393
Wed 31/1208:55SDQ - GUA
2 stops14h 45mCopa Airlines
Wed 7/106:24GUA - SDQ
2 stops17h 53mCopa Airlines
Deal found 5/12£399
Mon 22/1218:39SDQ - GUA
1 stop16h 55mCopa Airlines
Sun 28/1204:21GUA - SDQ
1 stop16h 35mCopa Airlines
Deal found 6/12£402
Thu 25/1212:40SDQ - GUA
2 stops10h 58mCopa Airlines
Thu 1/106:24GUA - SDQ
2 stops14h 31mCopa Airlines
Deal found 5/12£406
Sat 27/1212:40SDQ - GUA
2 stops10h 58mCopa Airlines
Sat 3/107:13GUA - SDQ
1 stop13h 42mCopa Airlines
Deal found 5/12£409
Mon 29/1218:39SDQ - GUA
2 stops28h 59mCopa Airlines
Mon 5/106:24GUA - SDQ
2 stops17h 53mCopa Airlines
Deal found 5/12£424
Tue 23/1208:55SDQ - GUA
2 stops14h 43mCopa Airlines
Tue 30/1206:24GUA - SDQ
2 stops27h 16mCopa Airlines
Deal found 6/12£440

Find flight deals from Santo Domingo to Guatemala City

Discover tips and strategies to find the most affordable flight options for your journey from Santo Domingo (SDQ) to Guatemala City (GUA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 8 December 2025.

Round-trip from

£232

One-way from

£160

Popular in

December

Cheapest in

May

Average price

£300
Copa Airlines
  • Copa Airlines
  • 5/2-12/2
  • 3 total stops
  • 25h 15m total
  • Santo Domingo to Guatemala City
Search Deals
JetBlue
  • JetBlue
  • 5/2
  • 1 total stop
  • 12h 58m total
  • Santo Domingo to Guatemala City
Search Deals
Highest demand for flights based on searches. 13% potential increase in price (£28 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease (£4 potential savings vs. average return price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Santo Domingo to Guatemala City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 8 December 2025.
Use the filters below to find and compare flights from Santo Domingo to Guatemala City that are best for you.

Fly from

Santo Domingo

Fly to

Guatemala City

Route

Depart

Return

Price

Santo DomingoGuatemala City

SDQ - GUA

SDQGUA

Santo Domingo Las Americas

Tue 14/4

08:43-21:41

2 stops14h 58m

Guatemala City La Aurora

Tue 21/4

04:26-16:14

1 stop9h 48m

£232

Santo DomingoGuatemala City

SDQ - GUA

SDQGUA

Santo Domingo Las Americas

Thu 5/2

06:00-21:40

2 stops17h 40m

Guatemala City La Aurora

Sat 7/2

06:24-22:39

2 stops14h 15m

£232

Santo DomingoGuatemala City

SDQ - GUA

SDQGUA

Santo Domingo Las Americas

Thu 2/4

18:37-09:36

1 stop16h 59m

Guatemala City La Aurora

Thu 9/4

04:26-22:51

1 stop16h 25m

£232

Santo DomingoGuatemala City

SDQ - GUA

SDQGUA

Santo Domingo Las Americas

Thu 12/3

06:00-21:40

2 stops17h 40m

Guatemala City La Aurora

Thu 19/3

13:16-22:40

1 stop7h 24m

£232

Santo DomingoGuatemala City

SDQ - GUA

SDQGUA

Santo Domingo Las Americas

Mon 2/2

19:05-09:34

1 stop16h 29m

Guatemala City La Aurora

Mon 9/2

10:34-02:17

1 stop13h 43m

£232

Santo DomingoGuatemala City

SDQ - GUA

SDQGUA

Santo Domingo Las Americas

Tue 24/2

18:39-09:34

1 stop16h 55m

Guatemala City La Aurora

Tue 3/3

16:27-10:48

1 stop16h 21m

£232

Santo DomingoGuatemala City

SDQ - GUA

SDQGUA

Santo Domingo Las Americas

Thu 12/2

11:57-23:11

1 stop13h 14m

Guatemala City La Aurora

Thu 19/2

10:34-22:39

1 stop10h 05m

£232

Santo DomingoGuatemala City

SDQ - GUA

SDQGUA

Santo Domingo Las Americas

Sat 7/2

19:05-08:55

1 stop15h 50m

Guatemala City La Aurora

Sat 14/2

10:34-02:17

1 stop13h 43m

£232

Santo DomingoGuatemala City

SDQ - GUA

SDQGUA

Santo Domingo Las Americas

Mon 9/2

19:05-09:34

1 stop16h 29m

Guatemala City La Aurora

Mon 16/2

06:24-02:17

2 stops17h 53m

£232

Santo DomingoGuatemala City

SDQ - GUA

SDQGUA

Santo Domingo Las Americas

Thu 5/2

04:15-15:13

1 stop12h 58m

£160

Flights are sorted by cheapest return flights first.

Deals found on 8/12

Showing 1-10 of 13 results
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Best time to book a flight from Santo Domingo to Guatemala City

Have a flexible travel schedule? Discover the best time to fly to Guatemala City from Santo Domingo with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santo Domingo to Guatemala City

How far ahead should I book a flight from Santo Domingo to Guatemala City?

Use this chart to determine the optimal time to book a return flight from Santo Domingo to Guatemala City. Price data was last updated on 5 December 2025.

The best time to book flights from Santo Domingo to Guatemala City is 34 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Santo Domingo to Guatemala City?

Currently, September is the cheapest month in which you can book a flight from Santo Domingo to Guatemala City (average of £103). Flying from Santo Domingo to Guatemala City in December is currently the most expensive (average of £188). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SDQ to GUA?

Find hourly flight availability from Santo Domingo to Guatemala City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 8 December 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Santo Domingo to Guatemala City as you normally would.

Related info for your journey

Find useful and relevant information for your journey from Santo Domingo to Guatemala City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santo Domingo to Guatemala City?

    For as low as £232, Copa Airlines can have you in Guatemala City from Santo Domingo in 14h 58m. The distance from Santo Domingo to Guatemala City is about 1405 mi.

  • Can I find deals for flights from Santo Domingo to Guatemala City that include hotel bookings?

    Yes. In addition to deals on Santo Domingo to Guatemala City flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Santo Domingo to Guatemala City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santo Domingo to Guatemala City.

  • Can I find deals for business class flights from Santo Domingo to Guatemala City?

    Yes. Cheapflights offers flight deals from Santo Domingo to Guatemala City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santo Domingo to Guatemala City?

    Currently, September is the cheapest month in which you can book a flight from Santo Domingo to Guatemala City (average of £103). Flying from Santo Domingo to Guatemala City in December is currently the most expensive (average of £188). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Complete your trip

Complete your trip to Guatemala City by adding a car hire and/or hotel booking to your travel itinerary.
Guatemala City car hire
Guatemala City La Aurora Airport car hire

Fly with Cheapflights

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How does Cheapflights help users find flights from Santo Domingo to Guatemala City?

Cheapflights makes it easy to find Santo Domingo to Guatemala City flights by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

Why should you use Cheapflights to find cheap flight tickets from Santo Domingo to Guatemala City?

By finding flights from multiple airlines and providers at completely no cost, Cheapflights helps millions of users like you annually find the best flights to Guatemala City from Santo Domingo.

Can Cheapflights find flights from Santo Domingo to Guatemala City with no change fees?

Users can book flights with no change fees policies with our dedicated filters. Book flights from Santo Domingo to Guatemala City flexibly with Cheapflights today.

Can Cheapflights notify me if prices for flights from Santo Domingo to Guatemala City become cheaper?

Yes, Cheapflights has a feature called Price Alert, which notifies users when flight prices change. Track prices for your flight to Guatemala City from Santo Domingo today and book when prices fit your budget.

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