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Cheap flights from Santa Cruz de la Sierra to Mexico City from £336

VVI — MEX
16 Oct — 23 Oct1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Santa Cruz de la Sierra to Mexico City

Enter your travel dates to find the best prices.

Cheapest flights from Santa Cruz de la Sierra to Mexico City

Mon 14/901:12 -
1 stop22h 53m
Mon 21/902:10 -
1 stop18h 34m
Deal found 11/9£580
Tue 15/911:47 -
1 stop15h 13m
Mon 28/901:20 -
1 stop19h 24m
Deal found 11/9£590
Thu 15/1001:12 -
1 stop25h 48m
Mon 19/1005:50 -
1 stop14h 54m
Deal found 14/9£597
Mon 5/1001:12 -
1 stop25h 48m
Fri 9/1001:20 -
1 stop19h 24m
Deal found 16/9£599
Tue 15/901:12 -
1 stop22h 53m
Wed 23/901:20 -
1 stop19h 24m
Deal found 11/9£602
Tue 15/901:12 -
1 stop25h 03m
Mon 21/902:10 -
1 stop18h 34m
Deal found 12/9£602
Mon 28/911:47 -
1 stop14h 28m
Tue 6/1001:20 -
1 stop24h 18m
Deal found 15/9£613
Tue 17/1111:49 -
1 stop26h 21m
Sat 28/1103:25 -
1 stop17h 13m
Deal found 11/9£622

Find flight deals from Santa Cruz de la Sierra to Mexico City

Round-trip from

£580

One-way from

£336

Popular in

June

Cheapest in

November

Average price

£521
Copa Airlines
  • Copa Airlines
  • 15/10-19/10
  • 2 total stops
  • 41h 36m total
  • Santa Cruz de la Sierra to Mexico City
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Copa Airlines
  • Copa Airlines
  • 23/12-31/12
  • 1 total stop
  • 12h 43m total
  • Santa Cruz de la Sierra to Mexico City
Search Deals
Highest demand for flights based on searches. 5% potential increase in price (£22 potential increase over avg. return price).
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Cheapest flight prices on average. 2% potential price decrease (£9 potential savings vs. average return price).
Search Deals
Average for round-trip flights in September 2026
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Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Santa Cruz de la Sierra to Mexico City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

Santa Cruz de la SierraMexico City

VVI Santa Cruz de la Sierra Viru Viru Intl - MEX Mexico City Benito Juarez

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Tue 22/12

01:10-12:10

1 stop13h 00m

Mexico City Benito Juarez

Wed 31/12

00:00-02:00

Nonstop0h 00m

£336

Santa Cruz de la SierraMexico City

VVI Santa Cruz de la Sierra Viru Viru Intl - MEX Mexico City Benito Juarez

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Mon 21/12

01:10-00:15

1 stop25h 05m

Mexico City Benito Juarez

Wed 31/12

00:00-02:00

Nonstop0h 00m

£338

Santa Cruz de la SierraMexico City

VVI Santa Cruz de la Sierra Viru Viru Intl - MEX Mexico City Benito Juarez

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Wed 11/11

11:41-00:15

1 stop14h 34m

Mexico City Benito Juarez

Wed 31/12

00:00-02:00

Nonstop0h 00m

£338

Santa Cruz de la SierraMexico City

VVI Santa Cruz de la Sierra Viru Viru Intl - MEX Mexico City Benito Juarez

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Tue 13/10

01:12-00:15

1 stop25h 03m

Mexico City Benito Juarez

Wed 31/12

00:00-02:00

Nonstop0h 00m

£352

Santa Cruz de la SierraMexico City

VVI Santa Cruz de la Sierra Viru Viru Intl - MEX Mexico City Benito Juarez

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Mon 5/10

01:12-00:15

1 stop25h 03m

Mexico City Benito Juarez

Wed 31/12

00:00-02:00

Nonstop0h 00m

£352

Santa Cruz de la SierraMexico City

VVI Santa Cruz de la Sierra Viru Viru Intl - MEX Mexico City Benito Juarez

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Tue 20/10

11:47-01:00

1 stop15h 13m

Mexico City Benito Juarez

Wed 31/12

00:00-02:00

Nonstop0h 00m

£352

Santa Cruz de la SierraMexico City

VVI Santa Cruz de la Sierra Viru Viru Intl - MEX Mexico City Benito Juarez

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Fri 12/3

03:45-18:25

1 stop16h 40m

Mexico City Benito Juarez

Wed 31/12

00:00-02:00

Nonstop0h 00m

£400

Santa Cruz de la SierraMexico City

VVI Santa Cruz de la Sierra Viru Viru Intl - MEX Mexico City Benito Juarez

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Wed 10/3

03:45-18:25

1 stop16h 40m

Mexico City Benito Juarez

Wed 31/12

00:00-02:00

Nonstop0h 00m

£400
Fastest return journey

Santa Cruz de la SierraMexico City

VVI Santa Cruz de la Sierra Viru Viru Intl - MEX Mexico City Benito Juarez

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Thu 11/3

03:45-12:15

1 stop10h 30m

Mexico City Benito Juarez

Wed 31/12

00:00-02:00

Nonstop0h 00m

£400

Santa Cruz de la SierraMexico City

VVI Santa Cruz de la Sierra Viru Viru Intl - MEX Mexico City Benito Juarez

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Thu 11/2

11:55-00:15

1 stop14h 20m

Mexico City Benito Juarez

Tue 2/3

05:55-03:40

1 stop19h 45m

£580

Flights are sorted by cheapest return flights first.

Deals found on 15/9

Showing 1-10 of 15 resultsSorted by cheapest first
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Best time to book a flight from Santa Cruz de la Sierra to Mexico City

Have a flexible travel schedule? Discover the best time to fly to Mexico City from Santa Cruz de la Sierra with our price prediction graph.
Estimated return price

Cheapflights Insights

Everything you need to know about your flight from Santa Cruz de la Sierra to Mexico City

How far ahead should I book a flight from Santa Cruz de la Sierra to Mexico City?

The price you pay for your flight from Santa Cruz de la Sierra to Mexico City may vary depending on when you book. For the best chance of a lower fare, look to book 30 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Santa Cruz de la Sierra to Mexico City?

Currently, November is the cheapest month in which you can book a flight from Santa Cruz de la Sierra to Mexico City (average of £501). Flying from Santa Cruz de la Sierra to Mexico City in June is currently the most expensive (average of £660). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost for a return flight from Santa Cruz de la Sierra to Mexico City?

Airfare is above average for this route at the moment.

Santa Cruz de la Sierra to Mexico City flights typically cost between £474 and £577 in September.
The cheapest return price found within the last 5 days was £580 on Copa Airlines (27 Sept–7 Oct).

Related info for your journey

  • How long is the flight from Santa Cruz de la Sierra to Mexico City?

    Copa Airlines can get you from Santa Cruz de la Sierra to Mexico City in just under 25h 48m. Your travel time can differ by up to . Santa Cruz de la Sierra and Mexico City are separated by a distance of 3534 mi.

  • Can I find deals for flights from Santa Cruz de la Sierra to Mexico City that include hotel bookings?

    Yes. In addition to deals on Santa Cruz de la Sierra to Mexico City flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Santa Cruz de la Sierra to Mexico City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Cruz de la Sierra to Mexico City.

  • Can I find deals for business class flights from Santa Cruz de la Sierra to Mexico City?

    Yes. Cheapflights offers flight deals from Santa Cruz de la Sierra to Mexico City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santa Cruz de la Sierra to Mexico City?

    Currently, November is the cheapest month in which you can book a flight from Santa Cruz de la Sierra to Mexico City (average of £501). Flying from Santa Cruz de la Sierra to Mexico City in June is currently the most expensive (average of £660). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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When you search for this flight from Santa Cruz de la Sierra to Mexico City, Cheapflights searches on 900+ travel sites to save you time finding great flight deals online. Additionally, we offer filter features so you can choose a preferred cabin class or airline, see different price ranges, and much more so you can book the flight for you.

Why should you use Cheapflights to find cheap flight tickets from Santa Cruz de la Sierra to Mexico City?

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Can Cheapflights find flights from Santa Cruz de la Sierra to Mexico City with no change fees?

Need flexible booking options for your flight to Mexico City from Santa Cruz de la Sierra? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

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Yes! Start tracking prices for Santa Cruz de la Sierra to Mexico City flights today and get alerted whenever prices for these flights change. To access this feature, click the bell icon next to the flight deals above, which will prompt you for a valid email address to receive your alerts.

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