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Cheap flights from Mexico City to Panama City from £128

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 14/11. Fares are subject to change and may not be available on all flights or dates of travel.
MEX — PTY
20 Jul — 27 Jul1
1 adult

Cheapflights Tip: The best prices from Mexico City Benito Juarez to Panama City Tocumen Intl are usually found in July or June, booked 85 days in advance, depart on a Wednesday or Monday and return on a Tuesday

Cheap flight deals from Mexico City to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Mexico City (MEX) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 15 July 2025.

Round-trip from

£234

One-way from

£128

Popular in

August

Cheapest in

July

Average price

£261

Good round-trip deal

£262 or less
Copa Airlines
  • Copa Airlines
  • 26/8-3/9
  • Nonstop
  • 7h 33m total
  • Mexico City to Panama City
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Avianca
  • Avianca
  • 14/11
  • 1 total stop
  • 16h 35m total
  • Mexico City to Panama City
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High demand for flights, 0% potential price rise
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Cheapest flight prices on average. 1% potential price decrease (£3 potential savings vs. average return price).
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Average for round-trip flights in July 2025
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Price to beat on a round-trip flight from Mexico City Benito Juarez to Panama City Tocumen Intl.
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Find flight deals from Mexico City to Panama City

Cheapest flights from Mexico City to Panama City
Explore the most affordable flight options available from Mexico City to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 15 July 2025.

Tue 26/802:00MEX - PTY
Nonstop3h 44mCopa Airlines
Wed 3/919:16PTY - MEX
Nonstop3h 49mCopa Airlines
Deal found 13/7£234
Tue 26/800:40MEX - PTY
1 stop8h 30mAvianca
Wed 3/917:25PTY - MEX
1 stop10h 40mAvianca
Deal found 13/7£241
Mon 11/808:55MEX - PTY
Nonstop3h 51mAeromexico
Fri 15/815:02PTY - MEX
Nonstop3h 38mAeromexico
Deal found 14/7£276
Mon 11/813:05MEX - PTY
Nonstop3h 44mMultiple Airlines
Fri 15/811:00PTY - MEX
1 stop13h 00mMultiple Airlines
Deal found 14/7£400

Cheapflights Fare Finder

Customise your flight search to find flights from Mexico City to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 15 July 2025.
Use the filters below to find and compare flights from Mexico City to Panama City that are best for you.

Fly from

Mexico City

Fly to

Panama City

Route

Depart

Return

Price

Mexico CityPanama City

MEX - PTY

MEXPTY

Mexico City Benito Juarez

Tue 26/8

02:00-06:44

Nonstop3h 44m

Panama City Tocumen Intl

Wed 3/9

19:16-22:05

Nonstop3h 49m

£234

Mexico CityPanama City

MEX - PTY

MEXPTY

Mexico City Benito Juarez

Tue 26/8

00:40-10:10

1 stop8h 30m

Panama City Tocumen Intl

Wed 3/9

17:25-03:05

1 stop10h 40m

£241

Mexico CityPanama City

MEX - PTY

MEXPTY

Mexico City Benito Juarez

Mon 11/8

08:55-13:46

Nonstop3h 51m

Panama City Tocumen Intl

Fri 15/8

15:02-17:40

Nonstop3h 38m

£276

Mexico CityPanama City

MEX - PTY

MEXPTY

Mexico City Benito Juarez

Mon 11/8

13:05-17:49

Nonstop3h 44m

Panama City Tocumen Intl

Fri 15/8

11:00-23:00

1 stop13h 00m

£400

Mexico CityPanama City

MEX - PTY

MEXPTY

Mexico City Benito Juarez

Fri 14/11

16:50-10:25

1 stop16h 35m

£128

Mexico CityPanama City

MEX - PTY

MEXPTY

Mexico City Benito Juarez

Sun 20/7

01:40-06:24

Nonstop3h 44m

£410

Mexico CityPanama City

MEX - PTY

MEXPTY

Mexico City Benito Juarez

Mon 4/8

04:40-20:37

2 stops14h 57m

£707

Flights are sorted by cheapest return flights first.

Deals found on 14/7

Best time to book a flight from Mexico City to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Mexico City with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mexico City to Panama City

How far ahead should I book a flight from Mexico City to Panama City?

Use this chart to determine the optimal time to book a return flight from Mexico City to Panama City. Price data was last updated on 11 July 2025.

The best time to book flights from Mexico City to Panama City is 85 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Mexico City to Panama City?

Currently, April is the cheapest month in which you can book a flight from Mexico City to Panama City (average of £763). Flying from Mexico City to Panama City in December is currently the most expensive (average of £1,051). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MEX to PTY?

Find hourly flight availability from Mexico City to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 15 July 2025.

One of the essential ways to save on airfare from Mexico City to Panama City is to remain as flexible as possible. Flights that are in the afternoon tend to be the most expensive. A flight at midday could potentially save you up to 38% on airfare.

Weekly flight availability from Mexico City to Panama City

Explore weekly flight availability from Mexico City to Panama City. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated 15 July 2025.

The most flights from MEX to PTY are scheduled on a Friday (10 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (8 on average).

How much does it cost for a return flight from Mexico City to Panama City?

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated 15 July 2025.
Get a feel of what it's like to fly with Copa Airlines, Aeromexico, andUnited Airlines from Mexico City to Panama City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.5
Good
1,483 reviews
Check prices

Food

6.8

Entertainment

6.8

Crew

8.1

Comfort

7.4

Overall

7.5

Boarding

7.8

Reviews

1 / 20
6.0
Good

Paul,May 2025

PTY - AUA

Had to use my phone for entertainment? Once we landed people were already out their seats and standing in the isles while the plane was still taxiing to the gate. This is unsafe and flight crew had a responsibility to ensure that people remain seated until the pilots turn off the seatbelt sign.
Copa Airlines
7.5
Good
1,483 reviews
Copa Airlines
7.5
Good
1,483 reviews
Check prices

Food

6.8

Entertainment

6.8

Crew

8.1

Comfort

7.4

Overall

7.5

Boarding

7.8

Reviews

1 / 20
6.0
Good

Paul,May 2025

PTY - AUA

Had to use my phone for entertainment? Once we landed people were already out their seats and standing in the isles while the plane was still taxiing to the gate. This is unsafe and flight crew had a responsibility to ensure that people remain seated until the pilots turn off the seatbelt sign.
Aeromexico
7.5
Good
1,717 reviews
Copa Airlines
7.5
Good
1,483 reviews
Check prices

Food

6.8

Entertainment

6.8

Crew

8.1

Comfort

7.4

Overall

7.5

Boarding

7.8

Reviews

1 / 20
6.0
Good

Paul,May 2025

PTY - AUA

Had to use my phone for entertainment? Once we landed people were already out their seats and standing in the isles while the plane was still taxiing to the gate. This is unsafe and flight crew had a responsibility to ensure that people remain seated until the pilots turn off the seatbelt sign.
United Airlines
7.4
Good
8,861 reviews
Copa Airlines
7.5
Good
1,483 reviews
Check prices

Food

6.8

Entertainment

6.8

Crew

8.1

Comfort

7.4

Overall

7.5

Boarding

7.8

Reviews

1 / 20
6.0
Good

Paul,May 2025

PTY - AUA

Had to use my phone for entertainment? Once we landed people were already out their seats and standing in the isles while the plane was still taxiing to the gate. This is unsafe and flight crew had a responsibility to ensure that people remain seated until the pilots turn off the seatbelt sign.
Avianca
6.7
Okay
2,379 reviews
Copa Airlines
7.5
Good
1,483 reviews
Check prices

Food

6.8

Entertainment

6.8

Crew

8.1

Comfort

7.4

Overall

7.5

Boarding

7.8

Reviews

1 / 20
6.0
Good

Paul,May 2025

PTY - AUA

Had to use my phone for entertainment? Once we landed people were already out their seats and standing in the isles while the plane was still taxiing to the gate. This is unsafe and flight crew had a responsibility to ensure that people remain seated until the pilots turn off the seatbelt sign.

Related info for your journey

Find useful and relevant information for your journey from Mexico City to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Mexico City to Panama City?

    If you book a flight from Mexico City to Panama City, you will be flying from Benito Juarez to Tocumen Intl. Flights to Panama City Tocumen Intl (PTY) from Mexico City Benito Juarez (MEX) take 3h 49m for a nonstop flight. There are 9 flights from Benito Juarez to Panama City per day from 1 airline.

  • How popular is this Mexico City to Panama City flight route?

    The Mexico City Benito Juarez to Panama City Tocumen Intl flight path was viewed by 2 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines flying from Mexico City to Panama City round-trip?

    Currently priced at £234, Copa Airlines will fly you from Mexico City to Panama City and back. In addition to Copa Airlines, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from Avianca and Aeromexico - these airlines can fly you to your destination from £241 and £276, respectively. Copa Airlines is currently priced 28% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from Mexico City to Panama City one-way?

    The cheapet airlines for a one-way flight from Mexico City to Panama City are Avianca (£128), Copa Airlines (£410), and United Airlines (£707).

  • What are the most reliable airlines from Mexico City to Panama City?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Mexico City to Panama City on time: Emirates (98%), Copa Airlines (96%), Aeromexico (95%).

  • What are the cheapest flights from Mexico City to Panama City?

    Looking for the cheapest flight from Mexico City to Panama City? While on average our users pay £393, our data indicates the cheapest price to be £213. The most popular route (Mexico City Benito Juarez - Panama City Tocumen Intl), is priced around £234.

  • Can I find deals for flights from Mexico City to Panama City that include hotel bookings?

    Yes. In addition to deals on Mexico City to Panama City flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Mexico City to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mexico City to Panama City.

  • Can I find deals for business class flights from Mexico City to Panama City?

    Yes. Cheapflights offers flight deals from Mexico City to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mexico City to Panama City?

    Currently, April is the cheapest month in which you can book a flight from Mexico City to Panama City (average of £763). Flying from Mexico City to Panama City in December is currently the most expensive (average of £1,051). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

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Top airline flying from Mexico City to Panama City

Discover the top airline that operate flights from Mexico City to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 15 July 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest£262Average£316FlexibilityNo cancel feeOn-time70%
Search Copa Airlines flights

Fly with Cheapflights

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How does Cheapflights help users find flights from Mexico City to Panama City?

Cheapflights makes it easy to find Mexico City to Panama City flights by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

Why should you use Cheapflights to find cheap flight tickets from Mexico City to Panama City?

By finding flights from multiple airlines and providers at completely no cost, Cheapflights helps millions of users like you annually find the best flights to Panama City from Mexico City.

Can Cheapflights find flights from Mexico City to Panama City with no change fees?

Users can book flights with no change fees policies with our dedicated filters. Book flights from Mexico City to Panama City flexibly with Cheapflights today.

Can Cheapflights notify me if prices for flights from Mexico City to Panama City become cheaper?

Yes! Start tracking prices for Mexico City to Panama City flights today and get alerted whenever prices for these flights change. To access this feature, click the bell icon next to the flight deals above, which will prompt you for a valid email address to receive your alerts.

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