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Cheap flights from Manchester to Santiago from £271

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/4. Fares are subject to change and may not be available on all flights or dates of travel.
MAN — SCL
26 Apr — 3 May1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Manchester to Santiago

Enter your travel dates to find the best prices.

Cheapest flights from Manchester to Santiago
Explore the most affordable flight options available from Manchester to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 27 March 2026.

Wed 3/618:45
MAN
-
SCL
2 stops33h 35m
Multiple Airlines
Sat 13/610:30
SCL
-
MAN
1 stop17h 40m
Multiple Airlines
Deal found 26/3£769
Thu 1/1019:20
MAN
-
SCL
2 stops38h 25m
Multiple Airlines
Sun 29/1101:35
SCL
-
MAN
2 stops41h 30m
Multiple Airlines
Deal found 26/3£790
Wed 11/1115:05
MAN
-
SCL
1 stop22h 05m
Multiple Airlines
Mon 23/1111:55
SCL
-
MAN
1 stop21h 10m
Multiple Airlines
Deal found 26/3£821
Thu 12/1123:15
MAN
-
SCL
2 stops37h 40m
Turkish Airlines
Thu 26/1111:40
SCL
-
MAN
2 stops43h 10m
Turkish Airlines
Deal found 26/3£840
Wed 11/1115:05
MAN
-
SCL
1 stop22h 05m
Multiple Airlines
Sat 28/1111:55
SCL
-
MAN
1 stop18h 10m
Multiple Airlines
Deal found 26/3£843
Thu 12/1114:05
MAN
-
SCL
2 stops46h 50m
Turkish Airlines
Fri 27/1111:40
SCL
-
MAN
2 stops43h 10m
Turkish Airlines
Deal found 25/3£850
Wed 1/713:10
MAN
-
SCL
2 stops48h 20m
Turkish Airlines
Wed 22/710:15
SCL
-
MAN
2 stops49h 15m
Turkish Airlines
Deal found 23/3£856
Tue 19/511:00
MAN
-
SCL
2 stops26h 45m
KLM
Tue 26/510:15
SCL
-
MAN
2 stops28h 50m
KLM
Deal found 24/3£856
Sun 15/1113:25
MAN
-
SCL
1 stop23h 45m
Multiple Airlines
Mon 23/1111:55
SCL
-
MAN
1 stop21h 50m
Multiple Airlines
Deal found 26/3£861
Tue 19/514:55
MAN
-
SCL
1 stop21h 55m
Multiple Airlines
Tue 26/510:15
SCL
-
MAN
2 stops28h 50m
Multiple Airlines
Deal found 24/3£868

Find flight deals from Manchester to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Manchester (MAN) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 27 March 2026.

Round-trip from

£769

One-way from

£271

Popular in

December

Cheapest in

June

Average price

£1,004
LEVEL
  • LEVEL
  • 3/6-13/6
  • 3 total stops
  • 51h 15m total
  • Manchester to Santiago
Search Deals
12/4
  • 12/4
  • 3 total stops
  • 49h 30m total
  • Manchester to Santiago
Search Deals
Highest demand for flights based on searches. 9% potential increase in price (£84 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease (£19 potential savings vs. average return price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Manchester to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 27 March 2026.
Use the filters below to find and compare flights from Manchester to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

ManchesterSantiago

MAN - SCL

MANSCL

Manchester

Wed 3/6

19:00-23:20

2 stops33h 20m

Santiago Arturo Merino Benitez

Sat 13/6

07:35-18:15

3 stops29h 40m

£839

ManchesterSantiago

MAN - SCL

MANSCL

Manchester

Sat 12/9

23:30-09:30

2 stops38h 00m

Santiago Arturo Merino Benitez

Sat 26/9

11:15-12:05

2 stops44h 50m

£879

ManchesterSantiago

MAN - SCL

MANSCL

Manchester

Sun 10/5

08:00-14:15

2 stops35h 15m

Santiago Arturo Merino Benitez

Sun 17/5

07:35-00:50

3 stops36h 15m

£922

ManchesterSantiago

MAN - SCL

MANSCL

Manchester

Sat 12/9

18:40-00:20

2 stops33h 40m

Santiago Arturo Merino Benitez

Sat 26/9

21:20-13:05

3 stops35h 45m

£930

ManchesterSantiago

MAN - SCL

MANSCL

Manchester

Sat 12/9

09:30-21:20

1 stop39h 50m

Santiago Arturo Merino Benitez

Sat 26/9

11:20-09:10

1 stop17h 50m

£1,015

ManchesterSantiago

MAN - SCL

MANSCL

Manchester

Mon 29/6

23:30-08:30

2 stops38h 00m

Santiago Arturo Merino Benitez

Wed 22/7

10:15-09:35

2 stops42h 20m

£1,017

ManchesterSantiago

MAN - SCL

MANSCL

Manchester

Sat 25/4

08:00-08:45

3 stops29h 45m

Santiago Arturo Merino Benitez

Sat 2/5

15:20-07:40

3 stops35h 20m

£1,079
Fastest return journey

ManchesterSantiago

MAN - SCL

MANSCL

Manchester

Fri 19/6

12:15-07:25

2 stops24h 10m

Santiago Arturo Merino Benitez

Sat 4/7

10:20-12:40

1 stop21h 20m

£1,209

ManchesterSantiago

MAN - SCL

MANSCL

Manchester

Fri 19/6

13:10-08:30

2 stops24h 20m

Santiago Arturo Merino Benitez

Sat 4/7

10:15-09:35

2 stops42h 20m

£1,236
Cheapest one-way

ManchesterSantiago

MAN - SCL

MANSCL

Manchester

Sun 12/4

08:15-04:45

3 stops49h 30m

£271

Flights are sorted by cheapest return flights first.

Deals found on 23/3

Showing 1-10 of 15 resultsSorted by cheapest first
1
2

Best time to book a flight from Manchester to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Manchester with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to Santiago

How far ahead should I book a flight from Manchester to Santiago?

Use this chart to determine the optimal time to book a return flight from Manchester to Santiago. Price data was last updated on 13 March 2026.

Booking 44 days in advance of your planned departure date is, on average, the best time to get cheap flights from Manchester to Santiago. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Manchester to Santiago?

Currently, December is the cheapest month in which you can book a flight from Manchester to Santiago (average of £359). Flying from Manchester to Santiago in July is currently the most expensive (average of £972). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost for a return flight from Manchester to Santiago?

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated 27 March 2026.
Read reviews from past customers who have flown with Delta,Air France, andIberia from Manchester to Santiago. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,341 reviews
Check prices

Comfort

7.9

Food

7.2

Overall

7.9

Entertainment

7.8

Crew

8.5

Boarding

8.1

Reviews

1 / 20
6.0
Good

Colin,Sept 2024

LHR - BOS

Delta One is very poor quality seating for first class. On multiple trips pieces have come off the seat. Staff and food have been good
Delta
7.9
Good
8,341 reviews
Delta
7.9
Good
8,341 reviews
Check prices

Comfort

7.9

Food

7.2

Overall

7.9

Entertainment

7.8

Crew

8.5

Boarding

8.1

Reviews

1 / 20
6.0
Good

Colin,Sept 2024

LHR - BOS

Delta One is very poor quality seating for first class. On multiple trips pieces have come off the seat. Staff and food have been good
Air France
7.4
Good
1,553 reviews
Delta
7.9
Good
8,341 reviews
Check prices

Comfort

7.9

Food

7.2

Overall

7.9

Entertainment

7.8

Crew

8.5

Boarding

8.1

Reviews

1 / 20
6.0
Good

Colin,Sept 2024

LHR - BOS

Delta One is very poor quality seating for first class. On multiple trips pieces have come off the seat. Staff and food have been good
Iberia
7.0
Good
3,157 reviews
Delta
7.9
Good
8,341 reviews
Check prices

Comfort

7.9

Food

7.2

Overall

7.9

Entertainment

7.8

Crew

8.5

Boarding

8.1

Reviews

1 / 20
6.0
Good

Colin,Sept 2024

LHR - BOS

Delta One is very poor quality seating for first class. On multiple trips pieces have come off the seat. Staff and food have been good
British Airways
6.7
Okay
7,822 reviews
Delta
7.9
Good
8,341 reviews
Check prices

Comfort

7.9

Food

7.2

Overall

7.9

Entertainment

7.8

Crew

8.5

Boarding

8.1

Reviews

1 / 20
6.0
Good

Colin,Sept 2024

LHR - BOS

Delta One is very poor quality seating for first class. On multiple trips pieces have come off the seat. Staff and food have been good

Related info for your journey

Find useful and relevant information for your journey from Manchester to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Manchester to Santiago?

    Departing from Manchester to Santiago will take you 38h. Manchester and Santiago are separated by a distance of 7251 mi.

  • What are the cheapest airlines flying from Manchester to Santiago round-trip?

    Our cheapest airline available from Manchester to Santiago is Delta. Our recent data shows that you can find tickets from as low as £690 on this airline. Additional options worth looking into are Air France and British Airways, starting at £757 and £805 round-trip. Delta is currently priced 32% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from Manchester to Santiago one-way?

    The cheapet airlines for a one-way flight from Manchester to Santiago are Vueling (£345), Iberia (£571), and British Airways (£707).

  • Can I find deals for flights from Manchester to Santiago that include hotel bookings?

    Yes. In addition to deals on Manchester to Santiago flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Manchester to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to Santiago.

  • Can I find deals for business class flights from Manchester to Santiago?

    Yes. Cheapflights offers flight deals from Manchester to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester to Santiago?

    Currently, December is the cheapest month in which you can book a flight from Manchester to Santiago (average of £359). Flying from Manchester to Santiago in July is currently the most expensive (average of £972). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar

Browse thousands of different options on Cheapflights for your next trip

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Top 4 airlines flying from Manchester to Santiago

Discover the top 4 airlines that operate flights from Manchester to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 27 March 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest£690Average£916FlexibilityNo cancel feeOn-timeN/A
Search Delta flights
Air FranceCheapest£757Average£1,177FlexibilityNo cancel feeOn-time77%
Search Air France flights
British AirwaysCheapest£805Average£1,046FlexibilityNo cancel feeOn-time70%
Search British Airways flights
IberiaCheapest£851Average£1,106FlexibilityNo cancel feeOn-time77%
Search Iberia flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Manchester to Santiago?

Cheapflights helps you search for flights from Manchester to Santiago via 900+ travel sites so you don’t have to. After performing a flight search, users can also filter their flight selection by filtering for price, number of stops, airlines, and so on.

Why should you use Cheapflights to find cheap flight tickets from Manchester to Santiago?

Cheapflights helps you find that perfect flight to Santiago from Manchester by searching from hundreds of airlines and agencies you know and love. We are also free to use, in case you were wondering!

Can Cheapflights find flights from Manchester to Santiago with no change fees?

Yes, we can. To see specific flights from Manchester to Santiago with no change fees, users can toggle flexible booking options after using the search form above to find flights.

Can Cheapflights notify me if prices for flights from Manchester to Santiago become cheaper?

Not ready to book yet? You can track prices for flights from Manchester to Santiago on Cheapflights with our Price Alert feature and get notified when better prices are available.

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