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Cheap flights from Guayaquil to Santo Domingo from £156

GYE — SDQ
29 Oct — 5 Nov1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Guayaquil to Santo Domingo

Enter your travel dates to find the best prices.

Cheapest flights from Guayaquil to Santo Domingo

Sat 10/1003:30 -
1 stop13h 25m
Sat 17/1012:45 -
1 stop11h 45m
Deal found 25/9£315
Mon 2/1118:38 -
1 stop6h 30m
Mon 9/1119:06 -
1 stop5h 49m
Deal found 29/9£318
Fri 27/1104:22 -
1 stop6h 23m
Sat 5/1208:55 -
1 stop9h 41m
Deal found 27/9£335
Mon 7/1203:18 -
1 stop8h 22m
Mon 14/1218:35 -
1 stop8h 40m
Deal found 28/9£343
Fri 9/1018:30 -
1 stop17h 42m
Sun 11/1012:42 -
1 stop23h 39m
Deal found 28/9£398
Sun 6/1212:22 -
1 stop23h 52m
Sun 13/1214:14 -
1 stop22h 08m
Deal found 28/9£415
Tue 27/1018:40 -
1 stop15h 29m
Tue 3/1119:06 -
1 stop17h 12m
Deal found 28/9£441
Mon 5/1018:30 -
1 stop16h 11m
Mon 12/1008:47 -
1 stop9h 43m
Deal found 28/9£469

Find flight deals from Guayaquil to Santo Domingo

Round-trip from

£315

One-way from

£156

Popular in

September

Cheapest in

April

Average price

£478
Avianca
  • Avianca
  • 10/10-17/10
  • 2 total stops
  • 25h 10m total
  • Guayaquil to Santo Domingo
Search Deals
11/1-31/12
  • 11/1-31/12
  • 1 total stop
  • 8h 22m total
  • Guayaquil to Santo Domingo
Search Deals
Highest demand for flights based on searches. 9% potential increase in price (£28 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease (£9 potential savings vs. average return price).
Search Deals
Average for round-trip flights in September 2026
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Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Guayaquil to Santo Domingo that are best for you.

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Price

Cheapest return flight
Fastest return journey

GuayaquilSanto Domingo

GYE Guayaquil Jose Joaquin de Olmedo - SDQ Santo Domingo Las Americas

GYESDQ

Guayaquil Jose Joaquin de Olmedo

Mon 26/10

03:18-12:25

1 stop8h 07m

Santo Domingo Las Americas

Wed 31/12

00:00-23:30

Nonstop0h 00m

£221

GuayaquilSanto Domingo

GYE Guayaquil Jose Joaquin de Olmedo - SDQ Santo Domingo Las Americas

GYESDQ

Guayaquil Jose Joaquin de Olmedo

Fri 5/2

14:43-11:42

1 stop19h 59m

Santo Domingo Las Americas

Wed 31/12

00:00-23:30

Nonstop0h 00m

£224

GuayaquilSanto Domingo

GYE Guayaquil Jose Joaquin de Olmedo - SDQ Santo Domingo Las Americas

GYESDQ

Guayaquil Jose Joaquin de Olmedo

Sat 14/11

14:47-11:45

1 stop19h 58m

Santo Domingo Las Americas

Wed 31/12

00:00-23:30

Nonstop0h 00m

£224

GuayaquilSanto Domingo

GYE Guayaquil Jose Joaquin de Olmedo - SDQ Santo Domingo Las Americas

GYESDQ

Guayaquil Jose Joaquin de Olmedo

Mon 21/12

12:22-02:08

1 stop12h 46m

Santo Domingo Las Americas

Wed 31/12

00:00-23:30

Nonstop0h 00m

£224

GuayaquilSanto Domingo

GYE Guayaquil Jose Joaquin de Olmedo - SDQ Santo Domingo Las Americas

GYESDQ

Guayaquil Jose Joaquin de Olmedo

Mon 30/11

12:25-22:58

1 stop9h 33m

Santo Domingo Las Americas

Wed 31/12

00:00-23:30

Nonstop0h 00m

£224

GuayaquilSanto Domingo

GYE Guayaquil Jose Joaquin de Olmedo - SDQ Santo Domingo Las Americas

GYESDQ

Guayaquil Jose Joaquin de Olmedo

Sat 28/11

18:38-13:10

1 stop17h 32m

Santo Domingo Las Americas

Wed 31/12

00:00-23:30

Nonstop0h 00m

£224

GuayaquilSanto Domingo

GYE Guayaquil Jose Joaquin de Olmedo - SDQ Santo Domingo Las Americas

GYESDQ

Guayaquil Jose Joaquin de Olmedo

Mon 16/11

21:15-11:50

2 stops13h 35m

Santo Domingo Las Americas

Wed 31/12

00:00-23:30

Nonstop0h 00m

£259

GuayaquilSanto Domingo

GYE Guayaquil Jose Joaquin de Olmedo - SDQ Santo Domingo Las Americas

GYESDQ

Guayaquil Jose Joaquin de Olmedo

Mon 5/10

18:30-10:54

1 stop15h 24m

Santo Domingo Las Americas

Wed 31/12

00:00-23:30

Nonstop0h 00m

£267

GuayaquilSanto Domingo

GYE Guayaquil Jose Joaquin de Olmedo - SDQ Santo Domingo Las Americas

GYESDQ

Guayaquil Jose Joaquin de Olmedo

Sun 15/11

21:15-11:50

2 stops13h 35m

Santo Domingo Las Americas

Wed 31/12

00:00-23:30

Nonstop0h 00m

£287

GuayaquilSanto Domingo

GYE Guayaquil Jose Joaquin de Olmedo - SDQ Santo Domingo Las Americas

GYESDQ

Guayaquil Jose Joaquin de Olmedo

Wed 21/10

04:14-11:41

1 stop6h 27m

Santo Domingo Las Americas

Sun 25/10

05:55-20:53

1 stop15h 58m

£318

Flights are sorted by cheapest return flights first.

Deals found on 29/9

Showing 1-10 of 18 resultsSorted by cheapest first
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Best time to book a flight from Guayaquil to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Guayaquil with our price prediction graph.
Estimated return price

Cheapflights Insights

Everything you need to know about your flight from Guayaquil to Santo Domingo

How far ahead should I book a flight from Guayaquil to Santo Domingo?

Booking 70 days in advance of your planned departure date is, on average, the best time to get cheap flights from Guayaquil to Santo Domingo. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Guayaquil to Santo Domingo?

Currently, April is the cheapest month in which you can book a flight from Guayaquil to Santo Domingo (average of £330). Flying from Guayaquil to Santo Domingo in September is currently the most expensive (average of £478). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost for a return flight from Guayaquil to Santo Domingo?

Airfare is below average for this route at the moment.

Guayaquil to Santo Domingo flights typically cost between £329 and £396 in October.
The cheapest return price found within the last 5 days was £315 on Avianca (10 Oct–17 Oct).

Related info for your journey

  • How long is the flight from Guayaquil to Santo Domingo?

    A quick flight from Guayaquil to Santo Domingo can take about 6h 27m. Copa Airlines provides one of the quickest options available for as low as £318. The distance from Guayaquil to Santo Domingo is about 1582 mi.

  • Can I find deals for flights from Guayaquil to Santo Domingo that include hotel bookings?

    Yes. In addition to deals on Guayaquil to Santo Domingo flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Guayaquil to Santo Domingo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Guayaquil to Santo Domingo.

  • Can I find deals for business class flights from Guayaquil to Santo Domingo?

    Yes. Cheapflights offers flight deals from Guayaquil to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Guayaquil to Santo Domingo?

    Currently, April is the cheapest month in which you can book a flight from Guayaquil to Santo Domingo (average of £330). Flying from Guayaquil to Santo Domingo in September is currently the most expensive (average of £478). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

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Can Cheapflights notify me if prices for flights from Guayaquil to Santo Domingo become cheaper?

Yes, Cheapflights offers price alerts on Guayaquil to Santo Domingo flights so you can book your travel at the perfect time. Price Alerts can be enabled by clicking the bell icon next to the flight deals above and providing your email address where you want to receive the alerts.

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