Cheap flights from Madrid, Spain to Santo Domingo from £249

MAD — SDQ
14 Dec — 21 Dec1
1 adult
1 adult, Economy, 0 bags
Cheapflights Tip: The best prices from Madrid Barajas to Santo Domingo Las Americas are usually found in September or October, booked 62 days in advance, depart on a Wednesday or Thursday and return on a Friday

Cheap flight deals from Madrid to Santo Domingo

Enter your travel dates to find the best prices.

Cheapest flights from Madrid to Santo Domingo

Thu 26/1116:20 -
Nonstop9h 15m
Thu 17/1223:05 -
Nonstop8h 20m
Deal found 12/11£521
Sun 22/1116:20 -
Nonstop9h 15m
Sun 22/1123:05 -
Nonstop8h 20m
Deal found 11/11£523
Thu 26/1116:20 -
Nonstop9h 15m
Thu 10/1223:05 -
Nonstop8h 20m
Deal found 11/11£524
Thu 19/1116:10 -
Nonstop9h 00m
Wed 2/1222:05 -
Nonstop8h 05m
Deal found 13/11£531
Thu 19/1116:10 -
Nonstop9h 00m
Fri 4/1222:05 -
Nonstop8h 05m
Deal found 10/11£535
Thu 19/1116:20 -
Nonstop9h 15m
Sun 20/1223:05 -
Nonstop8h 20m
Deal found 12/11£552
Mon 23/1116:10 -
Nonstop9h 00m
Thu 17/1222:05 -
Nonstop8h 05m
Deal found 12/11£553
Sun 22/1116:20 -
Nonstop9h 15m
Wed 23/1223:05 -
Nonstop8h 20m
Deal found 12/11£554
Thu 26/1116:20 -
Nonstop9h 15m
Thu 28/123:05 -
Nonstop8h 20m
Deal found 10/11£555
Mon 23/1116:10 -
Nonstop9h 00m
Mon 28/1222:05 -
Nonstop8h 05m
Deal found 11/11£556
Sun 6/1216:20 -
Nonstop9h 15m
Wed 23/1223:05 -
Nonstop8h 20m
Deal found 10/11£572
Mon 23/1116:10 -
Nonstop9h 00m
Tue 29/1222:05 -
Nonstop8h 05m
Deal found 11/11£581

Find flight deals from Madrid to Santo Domingo

Round-trip from

£521

One-way from

£249

Popular in

December

Cheapest in

September

Average price

£588

Good round-trip deal

£504 or less

Good one-way deal

£299 or less
World2Fly
  • World2Fly
  • 26/11-17/12
  • Nonstop
  • 17h 35m total
  • Madrid to Santo Domingo
Avianca
  • Avianca
  • 25/1-31/12
  • 1 total stop
  • 32h 40m total
  • Madrid to Santo Domingo
Highest demand for flights based on searches. 9% potential increase in price (£54 potential increase over avg. return price).
Cheapest flight prices on average. 4% potential price decrease (£21 potential savings vs. average return price).
Average for round-trip flights in November 2026
Price to beat on a round-trip flight from Madrid Barajas to Santo Domingo Las Americas.
Price to beat on a one-way flight from Madrid Barajas to Santo Domingo Las Americas.

Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Madrid to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight
Fastest return journey

MadridSanto Domingo

MAD Madrid Barajas - SDQ Santo Domingo Las Americas

MADSDQ

Madrid Barajas

Sun 3/1

16:20-20:35

Nonstop9h 15m

Santo Domingo Las Americas

Wed 31/12

00:00-05:30

Nonstop0h 00m

£343

MadridSanto Domingo

MAD Madrid Barajas - SDQ Santo Domingo Las Americas

MADSDQ

Madrid Barajas

Sat 27/2

16:20-11:50

1 stop24h 30m

Santo Domingo Las Americas

Wed 31/12

00:00-05:30

Nonstop0h 00m

£348

MadridSanto Domingo

MAD Madrid Barajas - SDQ Santo Domingo Las Americas

MADSDQ

Madrid Barajas

Tue 23/2

12:10-16:25

Nonstop9h 15m

Santo Domingo Las Americas

Wed 31/12

00:00-05:30

Nonstop0h 00m

£377

MadridSanto Domingo

MAD Madrid Barajas - SDQ Santo Domingo Las Americas

MADSDQ

Madrid Barajas

Wed 17/3

06:05-22:22

2 stops21h 17m

Santo Domingo Las Americas

Wed 31/12

00:00-05:30

Nonstop0h 00m

£469

MadridSanto Domingo

MAD Madrid Barajas - SDQ Santo Domingo Las Americas

MADSDQ

Madrid Barajas

Sat 21/11

11:15-15:06

1 stop32h 51m

Santo Domingo Las Americas

Wed 31/12

00:00-05:30

Nonstop0h 00m

£533

MadridSanto Domingo

MAD Madrid Barajas - SDQ Santo Domingo Las Americas

MADSDQ

Madrid Barajas

Tue 24/11

11:15-23:46

1 stop17h 31m

Santo Domingo Las Americas

Wed 31/12

00:00-05:30

Nonstop0h 00m

£535

MadridSanto Domingo

MAD Madrid Barajas - SDQ Santo Domingo Las Americas

MADSDQ

Madrid Barajas

Thu 19/11

11:00-13:41

2 stops31h 41m

Santo Domingo Las Americas

Wed 31/12

00:00-05:30

Nonstop0h 00m

£539

MadridSanto Domingo

MAD Madrid Barajas - SDQ Santo Domingo Las Americas

MADSDQ

Madrid Barajas

Thu 26/11

11:15-15:06

1 stop32h 51m

Santo Domingo Las Americas

Wed 31/12

00:00-05:30

Nonstop0h 00m

£572

MadridSanto Domingo

MAD Madrid Barajas - SDQ Santo Domingo Las Americas

MADSDQ

Madrid Barajas

Sat 12/12

12:10-03:34

2 stops20h 24m

Santo Domingo Las Americas

Wed 31/12

00:00-05:30

Nonstop0h 00m

£627

MadridSanto Domingo

MAD Madrid Barajas - SDQ Santo Domingo Las Americas

MADSDQ

Madrid Barajas

Sun 10/1

05:55-15:15

1 stop14h 20m

Santo Domingo Las Americas

Wed 31/12

00:00-05:30

Nonstop0h 00m

£648

Flights are sorted by cheapest return flights first.

Deals found on 11/11

Showing 1-10 of 23 resultsSorted by cheapest first
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Best time to book a flight from Madrid to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Madrid with our price prediction graph.
Estimated return price

Cheapflights Insights

Everything you need to know about your flight from Madrid to Santo Domingo

How far ahead should I book a flight from Madrid to Santo Domingo?

Booking 90 days in advance of your planned departure date is, on average, the best time to get cheap flights from Madrid to Santo Domingo. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Madrid to Santo Domingo?

Currently, September is the cheapest month in which you can book a flight from Madrid to Santo Domingo (average of £551). Flying from Madrid to Santo Domingo in December is currently the most expensive (average of £956). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MAD to SDQ?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Madrid to Santo Domingo as you normally would.

How much does it cost for a return flight from Madrid to Santo Domingo?

Airfare is typical for this route at the moment.

Madrid to Santo Domingo flights typically cost between £496 and £708 in November.
The cheapest return price found within the last 5 days was £521 on World2Fly (26 Nov–17 Dec).

Reviews of airlines servicing Santo Domingo

Read reviews from past customers who have flown with Air Europa and Iberia from Madrid to Santo Domingo. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Comfort

6.9

Boarding

7.1

Food

6.3

Overall

7.0

Crew

7.5

Entertainment

6.6

Reviews

1 / 20
8.0
Excellent

Esteban,Nov 2026

MAD - EZE

The excellent crew was great! The boarding for older people is an issue to be addressed by expediting it and making it easy for them

Comfort

6.9

Boarding

7.1

Food

6.3

Overall

7.0

Crew

7.5

Entertainment

6.6

Reviews

1 / 20
8.0
Excellent

Esteban,Nov 2026

MAD - EZE

The excellent crew was great! The boarding for older people is an issue to be addressed by expediting it and making it easy for them

Comfort

6.9

Boarding

7.1

Food

6.3

Overall

7.0

Crew

7.5

Entertainment

6.6

Reviews

1 / 20
8.0
Excellent

Esteban,Nov 2026

MAD - EZE

The excellent crew was great! The boarding for older people is an issue to be addressed by expediting it and making it easy for them

Related info for your journey

  • How popular is this Madrid to Santo Domingo flight route?

  • How long is the flight from Madrid to Santo Domingo?

    A quick flight from Madrid to Santo Domingo can take about 9h. Air Europa provides one of the quickest options available for as low as £680. The distance between Madrid and Santo Domingo is about 4154 mi. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.

  • What are the cheapest airlines flying from Madrid to Santo Domingo round-trip?

    Cheapflights users have booked flights from Madrid to Santo Domingo round-trip from £476. Other airlines that can offer you cheap pricing are Iberia, from £482, and Air Europa, from £533. Users have found that World2Fly is 28% cheaper than the other options available to this destination.

  • What are the most reliable airlines from Madrid to Santo Domingo?

    Before booking your flight to Santo Domingo from Madrid, check out the most reliable airlines to get you to your destination on time: World2Fly (100%), British Airways (94%), Air Europa( 88%).

  • Can I find deals for flights from Madrid to Santo Domingo that include hotel bookings?

    Yes. In addition to deals on Madrid to Santo Domingo flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Madrid to Santo Domingo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Madrid to Santo Domingo.

  • Can I find deals for business class flights from Madrid to Santo Domingo?

    Yes. Cheapflights offers flight deals from Madrid to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Madrid to Santo Domingo?

    Currently, September is the cheapest month in which you can book a flight from Madrid to Santo Domingo (average of £551). Flying from Madrid to Santo Domingo in December is currently the most expensive (average of £956). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Browse thousands of different options on Cheapflights for your next trip

Top 3 airlines flying from Madrid to Santo Domingo

AirlineCheapestAverageFlexibilityOn-time
World2FlyCheapest£476Average£639FlexibilityNo cancel feeOn-time91%
Search World2Fly flights
IberiaCheapest£482Average£850FlexibilityNo cancel feeOn-time77%
Search Iberia flights
Air EuropaCheapest£533Average£675FlexibilityNo cancel feeOn-time83%
Search Air Europa flights

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