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Cheap flights from Mexico City to Santo Domingo from £277

MEX — SDQ
12 Oct — 19 Oct1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Mexico City to Santo Domingo

Enter your travel dates to find the best prices.

Cheapest flights from Mexico City to Santo Domingo

Sat 31/1013:10 -
1 stop10h 58m
Sat 14/1108:55 -
1 stop15h 10m
Deal found 10/9£308
Mon 28/905:50 -
1 stop18h 35m
Sat 3/1012:42 -
1 stop13h 33m
Deal found 11/9£323
Sat 31/1002:00 -
1 stop7h 45m
Thu 12/1108:55 -
1 stop7h 35m
Deal found 9/9£331
Tue 6/1002:10 -
1 stop18h 46m
Tue 13/1012:12 -
1 stop14h 48m
Deal found 11/9£343
Fri 9/1015:30 -
1 stop17h 24m
Fri 16/1008:47 -
1 stop18h 13m
Deal found 10/9£345
Sun 29/1101:20 -
1 stop22h 48m
Mon 7/1214:14 -
1 stop10h 11m
Deal found 11/9£354
Sun 4/1002:10 -
1 stop22h 15m
Mon 12/1014:16 -
1 stop11h 59m
Deal found 10/9£357
Thu 8/1005:50 -
1 stop8h 24m
Thu 15/1008:47 -
1 stop17h 28m
Deal found 8/9£365
Sat 10/1001:20 -
1 stop8h 21m
Sun 18/1012:42 -
1 stop13h 33m
Deal found 7/9£367
Tue 3/1102:00 -
1 stop18h 58m
Tue 10/1108:55 -
1 stop12h 25m
Deal found 12/9£368
Tue 10/1101:20 -
1 stop19h 38m
Mon 16/1112:45 -
1 stop11h 40m
Deal found 8/9£379

Find flight deals from Mexico City to Santo Domingo

Round-trip from

£308

One-way from

£277

Popular in

July

Cheapest in

March

Average price

£275
Copa Airlines
  • Copa Airlines
  • 31/10-7/11
  • 2 total stops
  • 22h 53m total
  • Mexico City to Santo Domingo
Search Deals
Copa Airlines
  • Copa Airlines
  • 18/11-31/12
  • 1 total stop
  • 22h 42m total
  • Mexico City to Santo Domingo
Search Deals
Highest demand for flights based on searches. 6% potential increase in price (£13 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease (£3 potential savings vs. average return price).
Search Deals
Average for round-trip flights in September 2026
Search Deals

Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Mexico City to Santo Domingo that are best for you.

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Route

Depart

Return

Price

Cheapest return flight

Mexico CitySanto Domingo

MEX Mexico City Benito Juarez - SDQ Santo Domingo Las Americas

MEXSDQ

Mexico City Benito Juarez

Thu 31/12

15:30-11:42

1 stop18h 12m

Santo Domingo Las Americas

Wed 31/12

00:00-22:30

Nonstop0h 00m

£277
Fastest return journey

Mexico CitySanto Domingo

MEX Mexico City Benito Juarez - SDQ Santo Domingo Las Americas

MEXSDQ

Mexico City Benito Juarez

Thu 26/11

03:25-13:10

1 stop7h 45m

Santo Domingo Las Americas

Wed 31/12

00:00-22:30

Nonstop0h 00m

£277

Mexico CitySanto Domingo

MEX Mexico City Benito Juarez - SDQ Santo Domingo Las Americas

MEXSDQ

Mexico City Benito Juarez

Tue 3/11

02:00-11:45

1 stop7h 45m

Santo Domingo Las Americas

Wed 31/12

00:00-22:30

Nonstop0h 00m

£277

Mexico CitySanto Domingo

MEX Mexico City Benito Juarez - SDQ Santo Domingo Las Americas

MEXSDQ

Mexico City Benito Juarez

Mon 19/10

13:10-11:41

1 stop20h 31m

Santo Domingo Las Americas

Wed 31/12

00:00-22:30

Nonstop0h 00m

£277

Mexico CitySanto Domingo

MEX Mexico City Benito Juarez - SDQ Santo Domingo Las Americas

MEXSDQ

Mexico City Benito Juarez

Sat 26/9

00:25-11:42

1 stop9h 17m

Santo Domingo Las Americas

Wed 31/12

00:00-22:30

Nonstop0h 00m

£277

Mexico CitySanto Domingo

MEX Mexico City Benito Juarez - SDQ Santo Domingo Las Americas

MEXSDQ

Mexico City Benito Juarez

Thu 24/9

01:20-16:15

1 stop12h 55m

Santo Domingo Las Americas

Wed 31/12

00:00-22:30

Nonstop0h 00m

£277

Mexico CitySanto Domingo

MEX Mexico City Benito Juarez - SDQ Santo Domingo Las Americas

MEXSDQ

Mexico City Benito Juarez

Thu 12/11

02:00-11:45

1 stop7h 45m

Santo Domingo Las Americas

Wed 31/12

00:00-22:30

Nonstop0h 00m

£277

Mexico CitySanto Domingo

MEX Mexico City Benito Juarez - SDQ Santo Domingo Las Americas

MEXSDQ

Mexico City Benito Juarez

Sun 15/11

01:20-22:58

1 stop19h 38m

Santo Domingo Las Americas

Wed 31/12

00:00-22:30

Nonstop0h 00m

£277

Mexico CitySanto Domingo

MEX Mexico City Benito Juarez - SDQ Santo Domingo Las Americas

MEXSDQ

Mexico City Benito Juarez

Sun 20/9

02:10-02:25

1 stop22h 15m

Santo Domingo Las Americas

Wed 31/12

00:00-22:30

Nonstop0h 00m

£277

Mexico CitySanto Domingo

MEX Mexico City Benito Juarez - SDQ Santo Domingo Las Americas

MEXSDQ

Mexico City Benito Juarez

Mon 21/9

01:20-11:42

1 stop8h 22m

Santo Domingo Las Americas

Tue 29/9

14:16-00:15

1 stop11h 59m

£308

Flights are sorted by cheapest return flights first.

Deals found on 11/9

Showing 1-10 of 19 resultsSorted by cheapest first
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Best time to book a flight from Mexico City to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Mexico City with our price prediction graph.
Estimated return price

Cheapflights Insights

Everything you need to know about your flight from Mexico City to Santo Domingo

How far ahead should I book a flight from Mexico City to Santo Domingo?

To ensure you get the cheapest price possible for a flight from Mexico City to Santo Domingo, you should look to book at least 65 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Mexico City to Santo Domingo?

Currently, March is the cheapest month in which you can book a flight from Mexico City to Santo Domingo (average of £243). Flying from Mexico City to Santo Domingo in July is currently the most expensive (average of £303). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MEX to SDQ?

When flying from Mexico City to Santo Domingo, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

How much does it cost for a return flight from Mexico City to Santo Domingo?

Airfare is above average for this route at the moment.

Mexico City to Santo Domingo flights typically cost between £235 and £306 in October.
The cheapest return price found within the last 5 days was £308 on Copa Airlines (31 Oct–13 Nov).

Related info for your journey

  • How long is the flight from Mexico City to Santo Domingo?

    Copa Airlines can get you from Mexico City to Santo Domingo in just under 7h 32m. Your travel time can differ by up to . Mexico City and Santo Domingo are separated by a distance of 1919 mi.

  • Can I find deals for flights from Mexico City to Santo Domingo that include hotel bookings?

    Yes. In addition to deals on Mexico City to Santo Domingo flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Mexico City to Santo Domingo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mexico City to Santo Domingo.

  • Can I find deals for business class flights from Mexico City to Santo Domingo?

    Yes. Cheapflights offers flight deals from Mexico City to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mexico City to Santo Domingo?

    Currently, March is the cheapest month in which you can book a flight from Mexico City to Santo Domingo (average of £243). Flying from Mexico City to Santo Domingo in July is currently the most expensive (average of £303). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

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