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Cheap flights from London to São Tomé from £300

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 31/12. Fares are subject to change and may not be available on all flights or dates of travel.
LON — TMS
10 Sep — 17 Sep1
1 adult

Cheap flight deals from London to São Tomé

Discover tips and strategies to find the most affordable flight options for your journey from London (LON) to São Tomé (TMS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 5 September 2025.

Round-trip from

£515

One-way from

£300

Popular in

April

Cheapest in

November

Average price

£948
13/10-10/11
  • 13/10-10/11
  • 4 total stops
  • 71h 20m total
  • London to São Tomé
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31/12
  • 31/12
  • 2 total stops
  • 41h 15m total
  • London to São Tomé
Search Deals
Highest demand for flights based on searches. 5% potential increase in price (£46 potential increase over avg. return price).
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Cheapest flight prices on average. 5% potential price decrease (£42 potential savings vs. average return price).
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Average for round-trip flights in September 2025
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Find flight deals from London to São Tomé

Cheapest flights from London to São Tomé
Explore the most affordable flight options available from London to São Tomé. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 5 September 2025.

Mon 13/1020:10LGW - TMS
2 stops41h 00mMultiple Airlines
Mon 10/1112:50TMS - LGW
2 stops30h 20mMultiple Airlines
Deal found 5/9£515
Mon 13/1019:50LHR - TMS
2 stops41h 20mMultiple Airlines
Mon 10/1112:50TMS - LHR
2 stops32h 45mMultiple Airlines
Deal found 5/9£555
Wed 24/919:50LHR - TMS
2 stops41h 20mMultiple Airlines
Wed 8/1013:10TMS - LHR
2 stops22h 35mMultiple Airlines
Deal found 5/9£793
Fri 10/1018:45LHR - TMS
1 stop23h 35mTAP AIR PORTUGAL
Sat 25/1021:35TMS - LHR
1 stop15h 05mTAP AIR PORTUGAL
Deal found 4/9£933
Sun 28/921:45LGW - TMS
2 stops56h 35mMultiple Airlines
Sat 11/1021:35TMS - LGW
1 stop11h 20mMultiple Airlines
Deal found 4/9£1,023
Fri 10/1021:15LGW - TMS
3 stops45h 20mTAP AIR PORTUGAL
Sat 25/1021:35TMS - LGW
1 stop12h 15mTAP AIR PORTUGAL
Deal found 4/9£1,026
Wed 24/921:00LHR - TMS
3 stops21h 40mEthiopian Air
Wed 8/1007:00TMS - LHR
3 stops25h 05mEthiopian Air
Deal found 5/9£1,157
Sun 28/916:35LHR - TMS
2 stops20h 35mMultiple Airlines
Sat 11/1021:35TMS - LHR
1 stop11h 45mMultiple Airlines
Deal found 4/9£1,367
Sat 27/1218:30LHR - TMS
2 stops23h 35mTAP AIR PORTUGAL
Sat 10/122:25TMS - LHR
1 stop14h 15mTAP AIR PORTUGAL
Deal found 5/9£1,417

Cheapflights Fare Finder

 
Customise your flight search to find flights from London to São Tomé that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 5 September 2025.
Use the filters below to find and compare flights from London to São Tomé that are best for you.

Fly from

London

Fly to

São Tomé

Route

Depart

Return

Price

LondonSão Tomé

LGW - TMS

LGWTMS

London Gatwick

Mon 13/10

20:10-12:10

2 stops41h 00m

Sao Tome Is

Mon 10/11

12:50-19:10

2 stops30h 20m

£515

LondonSão Tomé

LHR - TMS

LHRTMS

London Heathrow

Mon 13/10

19:50-12:10

2 stops41h 20m

Sao Tome Is

Mon 10/11

12:50-21:35

2 stops32h 45m

£555

LondonSão Tomé

LHR - TMS

LHRTMS

London Heathrow

Thu 8/1

08:15-12:10

2 stops27h 55m

Sao Tome Is

Mon 19/1

13:10-21:35

2 stops32h 25m

£601

LondonSão Tomé

LGW - TMS

LGWTMS

London Gatwick

Thu 8/1

16:00-12:10

2 stops20h 10m

Sao Tome Is

Mon 19/1

13:10-15:45

2 stops26h 35m

£607

LondonSão Tomé

LGW - TMS

LGWTMS

London Gatwick

Fri 20/2

10:40-17:30

1 stop30h 50m

Sao Tome Is

Fri 6/3

20:00-15:45

2 stops19h 45m

£704

LondonSão Tomé

LHR - TMS

LHRTMS

London Heathrow

Fri 20/2

19:55-17:30

1 stop21h 35m

Sao Tome Is

Fri 6/3

20:00-12:40

2 stops16h 40m

£706

LondonSão Tomé

LHR - TMS

LHRTMS

London Heathrow

Thu 5/2

19:55-18:05

2 stops22h 10m

Sao Tome Is

Sun 15/2

20:00-17:30

2 stops21h 30m

£714

LondonSão Tomé

LGW - TMS

LGWTMS

London Gatwick

Thu 5/2

10:40-18:05

2 stops31h 25m

Sao Tome Is

Sun 15/2

20:00-09:50

2 stops13h 50m

£716

LondonSão Tomé

LHR - TMS

LHRTMS

London Heathrow

Sat 7/2

06:00-17:30

1 stop11h 30m

Sao Tome Is

Wed 18/2

13:10-12:40

2 stops23h 30m

£724

LondonSão Tomé

LGW - TMS

LGWTMS

London Gatwick

Thu 19/2

16:00-18:05

2 stops26h 05m

Sao Tome Is

Fri 27/2

20:00-15:45

2 stops19h 45m

£724

Flights are sorted by cheapest return flights first.

Deals found on 4/9

Showing 1-10 of 29 results
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Best time to book a flight from London to São Tomé

Have a flexible travel schedule? Discover the best time to fly to São Tomé from London with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from London to São Tomé

What is the cheapest time of day to fly from LON to TMS?

Find hourly flight availability from London to São Tomé. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 5 September 2025.

It’s optimal to fly from London to São Tomé in the morning. By choosing this option you can save up to 11% on the cost of your flight, compared to a flight at midday.

How much does it cost for a return flight from London to São Tomé?

Reviews of airlines servicing São Tomé

Get insights into the airlines that provide service to São Tomé. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to São Tomé. Reviews last updated 5 September 2025.
Get a feel of what it's like to fly with TAP AIR PORTUGAL from London to São Tomé by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
TAP AIR PORTUGAL
7.1
Good
1,972 reviews
Check prices

Crew

7.8

Food

6.2

Boarding

7.0

Entertainment

6.3

Overall

7.1

Comfort

7.1

Reviews

1 / 20
2.0
Mediocre

Claudia,Jul 2025

EWR - LIS

Never made the trip. Had to cancel due to multiple delays
TAP AIR PORTUGAL
7.1
Good
1,972 reviews
TAP AIR PORTUGAL
7.1
Good
1,972 reviews
Check prices

Crew

7.8

Food

6.2

Boarding

7.0

Entertainment

6.3

Overall

7.1

Comfort

7.1

Reviews

1 / 20
2.0
Mediocre

Claudia,Jul 2025

EWR - LIS

Never made the trip. Had to cancel due to multiple delays

Related info for your journey

Find useful and relevant information for your journey from London to São Tomé. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to São Tomé from London?

    Most people fly into Sao Tome Is (TMS) if they book a flight to São Tomé from London. On average, Sao Tome Is has 0 inbound flights from London per day from 1 airline. Sao Tome Is is conveniently located just 3.1 mi from São Tomé’s city center.

  • How long is the flight from London to São Tomé?

    TAP AIR PORTUGAL can get you from London to São Tomé in just under 30h 50m. Your travel time can differ by up to . The distance between London and São Tomé is about 3529 mi.

  • What is the cheapest airline to fly from London to São Tomé round-trip?

    Cheapflights users have booked flights from London to São Tomé round-trip from £676. Users have found that TAP AIR PORTUGAL is 32% cheaper than the other options available to this destination.

  • What are the most popular routes from London to São Tomé?

    While some choose either London Gatwick - Sao Tome Is or London City - Sao Tome Is, London Heathrow - Sao Tome Is is the most popular route from London to São Tomé.

  • Can I find deals for flights from London to São Tomé that include hotel bookings?

    Yes. In addition to deals on London to São Tomé flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from London to São Tomé?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from London to São Tomé.

  • Can I find deals for business class flights from London to São Tomé?

    Yes. Cheapflights offers flight deals from London to São Tomé by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for London to São Tomé

See prices for flight routes from nearby airports that may be better suited for you.
Heathrow to São Tomé flights
Gatwick to São Tomé flights

Top airline flying from London to São Tomé

Discover the top airline that operate flights from London to São Tomé. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 5 September 2025.
AirlineCheapestAverageFlexibilityOn-time
TAP AIR PORTUGALCheapest£676Average£903FlexibilityNo cancel feeOn-timeN/A
Search TAP AIR PORTUGAL flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from London to São Tomé?

Cheapflights goes through 900+ travel sites to look for the best flight deals for flights from London to São Tomé. Too many options? Cheapflights also provides filters for things like airlines, price ranges, and number of stops to help you make a decision easily.

Why should you use Cheapflights to find cheap flight tickets from London to São Tomé?

By finding flights from multiple airlines and providers at completely no cost, Cheapflights helps millions of users like you annually find the best flights to São Tomé from London.

Can Cheapflights find flights from London to São Tomé with no change fees?

Cheapflights does show flights with no change fees to all users. To see these options for flights from London to São Tomé, users can toggle the no change fees filter when performing a flight search.

Can Cheapflights notify me if prices for flights from London to São Tomé become cheaper?

Yes, Cheapflights offers price alerts on London to São Tomé flights so you can book your travel at the perfect time. Price Alerts can be enabled by clicking the bell icon next to the flight deals above and providing your email address where you want to receive the alerts.

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