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Cheap flights from London Heathrow Airport to São Tomé from £423

LHR — TMS
14 Nov — 21 Nov1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Heathrow to São Tomé

Enter your travel dates to find the best prices.

Cheapest flights from Heathrow to São Tomé

Fri 13/1108:15 -
1 stop33h 15m
Fri 20/1120:00 -
2 stops22h 55m
Deal found 12/10£683
Tue 3/1108:15 -
2 stops33h 15m
Fri 13/1118:20 -
2 stops24h 35m
Deal found 12/10£685
Fri 13/1118:30 -
1 stop11h 50m
Sat 21/1107:50 -
1 stop13h 45m
Deal found 12/10£702
Sat 14/1106:00 -
1 stop11h 30m
Sat 21/1122:25 -
1 stop13h 00m
Deal found 12/10£724
Sat 31/1006:00 -
1 stop11h 30m
Sat 7/1122:25 -
1 stop14h 15m
Deal found 14/10£810
Sat 14/1112:25 -
2 stops29h 05m
Fri 4/1218:20 -
2 stops23h 10m
Deal found 15/10£835
Wed 18/1118:30 -
2 stops47h 00m
Sun 6/1218:20 -
2 stops42h 20m
Deal found 13/10£847
Thu 12/1118:30 -
2 stops24h 25m
Sat 21/1122:25 -
1 stop13h 00m
Deal found 14/10£862

Find flight deals from Heathrow to São Tomé

Round-trip from

£683

One-way from

£423

Popular in

February

Cheapest in

November

Average price

£1,289
TAP AIR PORTUGAL
  • TAP AIR PORTUGAL
  • 13/11-20/11
  • 3 total stops
  • 56h 10m total
  • London to São Tomé
Search Deals
11/11-31/12
  • 11/11-31/12
  • 3 total stops
  • 44h 45m total
  • London to São Tomé
Search Deals
Highest demand for flights based on searches. 10% potential increase in price (£94 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease (£34 potential savings vs. average return price).
Search Deals
Average for round-trip flights in October 2026
Search Deals

Cheapflights Fare Finder

 
Use the filters below to find and compare flights from London Heathrow Airport to São Tomé that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

LondonSão Tomé

LHR London Heathrow - TMS Sao Tome Is

LHRTMS

London Heathrow

Wed 11/11

18:30-17:30

2 stops47h 00m

Sao Tome Is

Wed 31/12

00:00-01:00

Nonstop0h 00m

£429
Fastest return journey

LondonSão Tomé

LHR London Heathrow - TMS Sao Tome Is

LHRTMS

London Heathrow

Sat 31/10

06:00-17:30

1 stop11h 30m

Sao Tome Is

Sat 7/11

22:25-12:40

1 stop14h 15m

£810

LondonSão Tomé

LHR London Heathrow - TMS Sao Tome Is

LHRTMS

London Heathrow

Sat 14/11

12:25-17:30

2 stops29h 05m

Sao Tome Is

Fri 4/12

18:20-17:30

2 stops23h 10m

£835

LondonSão Tomé

LHR London Heathrow - TMS Sao Tome Is

LHRTMS

London Heathrow

Sat 20/2

12:25-17:30

2 stops29h 05m

Sao Tome Is

Sun 28/2

18:20-22:40

2 stops28h 20m

£844

LondonSão Tomé

LHR London Heathrow - TMS Sao Tome Is

LHRTMS

London Heathrow

Wed 18/11

18:30-17:30

2 stops47h 00m

Sao Tome Is

Sun 6/12

18:20-12:40

2 stops42h 20m

£847

LondonSão Tomé

LHR London Heathrow - TMS Sao Tome Is

LHRTMS

London Heathrow

Thu 12/11

16:30-18:55

2 stops26h 25m

Sao Tome Is

Sat 21/11

22:25-22:40

1 stop24h 15m

£863

LondonSão Tomé

LHR London Heathrow - TMS Sao Tome Is

LHRTMS

London Heathrow

Fri 30/10

06:00-18:55

2 stops12h 55m

Sao Tome Is

Sat 7/11

22:25-17:30

1 stop19h 05m

£869

LondonSão Tomé

LHR London Heathrow - TMS Sao Tome Is

LHRTMS

London Heathrow

Fri 25/12

19:55-17:30

2 stops45h 35m

Sao Tome Is

Wed 31/12

00:00-01:00

Nonstop0h 00m

£876

LondonSão Tomé

LHR London Heathrow - TMS Sao Tome Is

LHRTMS

London Heathrow

Sat 14/11

06:00-17:30

1 stop11h 30m

Sao Tome Is

Fri 4/12

20:00-12:40

2 stops16h 40m

£893

LondonSão Tomé

LHR London Heathrow - TMS Sao Tome Is

LHRTMS

London Heathrow

Thu 19/11

19:55-18:55

2 stops23h 00m

Sao Tome Is

Sun 6/12

20:00-21:35

2 stops25h 35m

£895

Flights are sorted by cheapest return flights first.

Deals found on 12/10

Showing 1-10 of 11 resultsSorted by cheapest first
1
2

Best time to book a flight from Heathrow to São Tomé

Have a flexible travel schedule? Discover the best time to fly to São Tomé from Heathrow with our price prediction graph.
Estimated return price

Reviews of airlines servicing São Tomé

Check out reviews from past customers who have flown with TAP AIR PORTUGAL from London Heathrow Airport to São Tomé to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
TAP AIR PORTUGAL
7.2
Good
2,378 reviews
Check prices

Crew

7.9

Comfort

7.2

Food

6.3

Overall

7.2

Entertainment

6.4

Boarding

7.1

Reviews

1 / 20
4.0
Okay

Bhairav,Jun 2026

LHR - LIS

Flew business. Uncomfortable seats and so so food and drink. Only thing attractive was the price.
TAP AIR PORTUGAL
7.2
Good
2,378 reviews
TAP AIR PORTUGAL
7.2
Good
2,378 reviews
Check prices

Crew

7.9

Comfort

7.2

Food

6.3

Overall

7.2

Entertainment

6.4

Boarding

7.1

Reviews

1 / 20
4.0
Okay

Bhairav,Jun 2026

LHR - LIS

Flew business. Uncomfortable seats and so so food and drink. Only thing attractive was the price.

Related info for your journey

  • What airport do you fly into for flights to São Tomé from London Heathrow?

    Sao Tome Is (TMS) is the airport you will fly into if you book a flight from London Heathrow to São Tomé. You should not have trouble finding flights to Sao Tome Is from London Heathrow; the airport handles an average of 0 inbound flights from London Heathrow per day. You should also have plenty of airline options to choose from since 1 airline has flights to the São Tomé airport from London Heathrow. It is only a 3.1 mi journey from Sao Tome Is (TMS) to São Tomé’s city center.

  • How long is the flight from London Heathrow Airport to São Tomé?

    Departing from London Heathrow Airport to São Tomé will take you 26h 25m. The distance between London Heathrow Airport and São Tomé is about 3552 mi.

  • What is the cheapest airline to fly from London Heathrow Airport to São Tomé round-trip?

    Cheapflights users have booked flights from London Heathrow Airport to São Tomé round-trip from £717. You may be able to fly from London Heathrow Airport to São Tomé for 31% less than the average price by searching for this airline.

  • Can I find deals for flights from Heathrow to São Tomé that include hotel bookings?

    Yes. In addition to deals on Heathrow to São Tomé flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Heathrow to São Tomé?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Heathrow to São Tomé.

  • Can I find deals for business class flights from Heathrow to São Tomé?

    Yes. Cheapflights offers flight deals from Heathrow to São Tomé by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for Heathrow to São Tomé

Gatwick to São Tomé flights

Top airline flying from Heathrow to São Tomé

AirlineCheapestAverageFlexibilityOn-time
TAP AIR PORTUGALCheapest£717Average£865FlexibilityNo cancel feeOn-timeN/A
Search TAP AIR PORTUGAL flights

Fly with Cheapflights

How does Cheapflights help users find flights from Heathrow to São Tomé?

When you search for this flight from Heathrow to São Tomé, Cheapflights searches on 900+ travel sites to save you time finding great flight deals online. Additionally, we offer filter features so you can choose a preferred cabin class or airline, see different price ranges, and much more so you can book the flight for you.

Why should you use Cheapflights to find cheap flight tickets from Heathrow to São Tomé?

Cheapflights helps you find that perfect flight to São Tomé from Heathrow by searching from hundreds of airlines and agencies you know and love. We are also free to use, in case you were wondering!

Can Cheapflights find flights from Heathrow to São Tomé with no change fees?

Certainly. Search results for flights to São Tomé from Heathrow shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Heathrow to São Tomé become cheaper?

Yes, Cheapflights offers price alerts on Heathrow to São Tomé flights so you can book your travel at the perfect time. Price Alerts can be enabled by clicking the bell icon next to the flight deals above and providing your email address where you want to receive the alerts.

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