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£388+ Cheap flights from Panama City

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/7. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
PTY — LHR
15 May — 22 May1
1 adult
1 adult, Economy, 0 bags

Find flights from Panama City within your budget

 
Find flights departing from Panama City that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 15 April 2026. In the last 7 days, Cheapflights users made a total of 858,174 searches

Fly to

Route

Depart

Return

Price

Cheapest return flight

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Wed 13/5

22:20-13:25

1 stop32h 05m

Brussels Bruxelles-National

Sun 17/5

14:25-20:25

1 stop37h 00m

£628

Panama CityLondon

PTY - STN

PTYSTN

Panama City Tocumen Intl

Wed 29/4

22:20-22:10

1 stop17h 50m

London Stansted

Sun 3/5

17:35-20:25

1 stop32h 50m

£660

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Sat 10/10

20:25-17:40

1 stop14h 15m

Brussels Bruxelles-National

Tue 3/11

10:45-19:45

1 stop15h 00m

£683

Panama CityDüsseldorf

PTY - DUS

PTYDUS

Panama City Tocumen Intl

Mon 25/5

22:20-09:00

1 stop27h 40m

Duesseldorf Intl

Fri 29/5

18:45-20:25

1 stop32h 40m

£692

Panama CityLondon

PTY - LHR

PTYLHR

Panama City Tocumen Intl

Mon 4/5

15:30-07:55

1 stop34h 25m

London Heathrow

Thu 7/5

06:50-19:31

2 stops18h 41m

£697

Panama CityLondon

PTY - STN

PTYSTN

Panama City Tocumen Intl

Mon 4/5

22:20-09:55

1 stop29h 35m

London Stansted

Sun 10/5

10:50-20:25

1 stop39h 35m

£698

Panama CityLondon

PTY - STN

PTYSTN

Panama City Tocumen Intl

Mon 4/5

22:20-09:55

1 stop29h 35m

London Stansted

Wed 6/5

17:45-18:30

2 stops30h 45m

£714
Fastest return journey

Panama CityLondon

PTY - LGW

PTYLGW

Panama City Tocumen Intl

Sun 24/5

20:25-16:25

1 stop14h 00m

London Gatwick

Thu 28/5

10:00-18:40

1 stop14h 40m

£720

Panama CityLondon

PTY - LGW

PTYLGW

Panama City Tocumen Intl

Sun 17/5

20:25-16:25

1 stop14h 00m

London Gatwick

Sun 31/5

17:25-18:40

1 stop31h 15m

£728

Panama CityLondon

PTY - STN

PTYSTN

Panama City Tocumen Intl

Sun 17/5

20:05-22:10

1 stop20h 05m

London Stansted

Sun 31/5

10:50-20:25

1 stop39h 35m

£752

Flights are sorted by cheapest return flights first.

Deals found on 10/4

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from Panama City

Have a flexible travel schedule? Discover the best time to fly from Panama City with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama City

Get recent, data-driven insights about flights from Panama City including ideal travel times, pricing trends, and more.

When is the best time to book a flight from Panama City?

Use this chart to determine the optimal time to book a return flight from Panama City to Heathrow. Price data was last updated on 10 April 2026.

Booking 28 days in advance of your planned departure date is, on average, the best time to get cheap flights from Panama City. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Panama City?

Currently, February is the cheapest month in which you can book a flight from Panama City (average of £581). Flying from Panama City in January will prove the most costly (average of £783). There are multiple factors that influence the price of a flight so comparing airlines, departure airports and times can help keep costs down.

Which airlines fly from Panama City?

Many airlines operate round-trip flights from Panama City: Turkish Airlines, KLM, Air France. These airlines fly to the following popular destinations: London.

Copa Airlines
Copa Airlines
From £71
Turkish Airlines
Turkish Airlines
From £632
Air Panama
Air Panama
From £113
Air Europa
Air Europa
From £519

What are popular destinations to fly to from Panama City?

If you’re flying from Panama City, these routes are more frequently taken by airlines Sao Paulo (244 flights per day), San José (164 flights per day) and Guatemala City (117 flights per day).

New York
New York
From £481
Bogotá El Dorado
Bogotá El Dorado
From £181
David Enrique Malek
David Enrique Malek
From £59
Los Angeles Los Angeles
Los Angeles Los Angeles
From £331

What is the cheapest place to fly to from Panama City?

The cheapest city to fly to from Panama City is David Enrique Malek, with prices starting at £59. Explore other affordable destinations below.

David Enrique Malek
David Enrique Malek
From £59
Bocas Del Toro
Bocas Del Toro
From £96
Medellín Jose Maria Cordova Intl
Medellín Jose Maria Cordova Intl
From £99
Cali Alfonso B. Aragon Intl
Cali Alfonso B. Aragon Intl
From £137

Airline reviews for flights from Panama City

Get insights into the airlines that provide service from Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing airline for your flight from Panama City. In the last 7 days, Cheapflights users made a total of 858,174 searches.
Read through reviews of airlines serving Panama City, such as KLM,Air France, andTurkish Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7.8
Good
1,499 reviews
Check prices

Entertainment

7.2

Boarding

7.8

Overall

7.8

Crew

8.4

Comfort

7.7

Food

7.3

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
KLM
7.8
Good
1,499 reviews
KLM
7.8
Good
1,499 reviews
Check prices

Entertainment

7.2

Boarding

7.8

Overall

7.8

Crew

8.4

Comfort

7.7

Food

7.3

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
Air France
7.4
Good
1,570 reviews
KLM
7.8
Good
1,499 reviews
Check prices

Entertainment

7.2

Boarding

7.8

Overall

7.8

Crew

8.4

Comfort

7.7

Food

7.3

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
Turkish Airlines
7.3
Good
4,306 reviews
KLM
7.8
Good
1,499 reviews
Check prices

Entertainment

7.2

Boarding

7.8

Overall

7.8

Crew

8.4

Comfort

7.7

Food

7.3

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas

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Direct flights from Panama

Book a direct flight from one of these other cities located in Panama.
Direct flights from Panama City

Related info for your journey

Access useful and relevant information related to your journey from Panama City. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 15 April 2026.

  • What are the most popular destinations to fly to from Panama City?

    This month, the top selected destinations from Panama City are Bogotá, Bocas del Toro, David. Throughout the year, Bogotá, Cancún, Cartagena are some of the top choices made by users flying from Panama City.

  • What is the cheapest flight from Panama City to anywhere?

    Users have flown out of Panama City for as low as £59 to David (prices may vary depending on the airline and departure time). On average, users have booked flights for £549 to fly from Panama City.

  • What are the cheapest airlines flying from Panama City to anywhere?

    Over the past few days, we've found that Wingo, Copa Airlines, and Air Panama have the cheapest prices from Panama City. Wingo flights from Panama City to Medellín Jose Maria Cordova Intl (£52), Copa Airlines flights from Panama City to David Enrique Malek (£71), and Air Panama flights from Panama City to Bocas Del Toro (£113).

  • What is the cheapest premium economy flight from Panama City?

    Here are some of the cheapest offers we have found for the cheapest premium economy flights from Panama City.
    Panama City Tocumen Intl to Paris Charles de Gaulle Airport from £962
    Panama City Tocumen Intl to Amsterdam from £1,855

  • What is the cheapest month to fly from Panama City?

    At the present moment the cheapest month to fly from Panama City is currently February; with January being the most expensive. Prices will vary depending on multiple factors such as booking in advance, airline and departure airports and times.

  • Where are the cheapest places to fly to from Panama City?

    Check out the cheapest flights from Panama City to embark to:
    Travel from Panama City to London from £678 round trip

  • How does Cheapflights help users find flights from Panama City?

    Cheapflights makes it easy to find flights from Panama City by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

  • Why should you use Cheapflights to find cheap flight tickets from Panama City?

    Cheapflights taps into our reliable network of hundreds of airlines and travel agencies to find the best deals for flights from Panama City for you. Better yet — we are completely free to use.

  • Can Cheapflights find flights from Panama City with no change fees?

    Users can book flights with no change fees policies with our dedicated filters. Book flights from Panama City flexibly with Cheapflights today.

  • Can Cheapflights notify me if prices for flights from Panama City become cheaper?

    Yes, Cheapflights has a feature called Price Alerts, which offers users the ability to be notified when flight prices change. Track prices for your flight from Panama City today and book when you’re ready!

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How does Cheapflights help users find flights from Panama City?

Cheapflights makes it easy to find flights from Panama City by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

Why should you use Cheapflights to find cheap flight tickets from Panama City?

Cheapflights taps into our reliable network of hundreds of airlines and travel agencies to find the best deals for flights from Panama City for you. Better yet — we are completely free to use.

Can Cheapflights find flights from Panama City with no change fees?

Users can book flights with no change fees policies with our dedicated filters. Book flights from Panama City flexibly with Cheapflights today.

Can Cheapflights notify me if prices for flights from Panama City become cheaper?

Yes, Cheapflights has a feature called Price Alerts, which offers users the ability to be notified when flight prices change. Track prices for your flight from Panama City today and book when you’re ready!

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