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£341+ Cheap flights from Panama City

PTY — LHR
2 Oct — 9 Oct1
1 adult
1 adult, Economy, 0 bags

Find flights from Panama City within your budget

 

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Cheapest return flight
Fastest return journey

Panama CityValencia

PTY Panama City Tocumen Intl - VLN Valencia

PTYVLN

Panama City Tocumen Intl

Tue 22/9

09:03-12:13

Nonstop2h 10m

Valencia

Tue 29/9

13:43-15:01

Nonstop2h 18m

£341

Panama CityValencia

PTY Panama City Tocumen Intl - VLN Valencia

PTYVLN

Panama City Tocumen Intl

Fri 25/9

09:03-12:13

Nonstop2h 10m

Valencia

Wed 30/9

13:43-15:01

Nonstop2h 18m

£341

Panama CityValencia

PTY Panama City Tocumen Intl - VLN Valencia

PTYVLN

Panama City Tocumen Intl

Sun 18/10

11:43-14:53

Nonstop2h 10m

Valencia

Sat 31/10

16:03-17:21

Nonstop2h 18m

£428

Panama CityValencia

PTY Panama City Tocumen Intl - VLN Valencia

PTYVLN

Panama City Tocumen Intl

Tue 20/10

11:43-14:53

Nonstop2h 10m

Valencia

Thu 29/10

16:03-17:21

Nonstop2h 18m

£428

Panama CityValencia

PTY Panama City Tocumen Intl - VLN Valencia

PTYVLN

Panama City Tocumen Intl

Tue 20/10

11:43-14:53

Nonstop2h 10m

Valencia

Sat 31/10

16:03-17:21

Nonstop2h 18m

£453

Panama CityValencia

PTY Panama City Tocumen Intl - VLN Valencia

PTYVLN

Panama City Tocumen Intl

Thu 15/10

11:43-14:53

Nonstop2h 10m

Valencia

Mon 26/10

16:03-17:21

Nonstop2h 18m

£468

Panama CityValencia

PTY Panama City Tocumen Intl - VLN Valencia

PTYVLN

Panama City Tocumen Intl

Sun 11/10

11:43-14:53

Nonstop2h 10m

Valencia

Sun 25/10

16:03-17:21

Nonstop2h 18m

£468

Panama CityValencia

PTY Panama City Tocumen Intl - VLN Valencia

PTYVLN

Panama City Tocumen Intl

Wed 28/10

11:43-14:53

Nonstop2h 10m

Valencia

Wed 25/11

16:03-17:21

Nonstop2h 18m

£488

Panama CityValencia

PTY Panama City Tocumen Intl - VLN Valencia

PTYVLN

Panama City Tocumen Intl

Sat 3/10

11:43-14:53

Nonstop2h 10m

Valencia

Thu 8/10

16:03-17:21

Nonstop2h 18m

£506

Panama CityBrussels

PTY Panama City Tocumen Intl - BRU Brussels Bruxelles-National

PTYBRU

Panama City Tocumen Intl

Wed 4/11

21:30-17:45

1 stop14h 15m

Brussels Bruxelles-National

Fri 20/11

10:45-19:45

1 stop15h 00m

£621

Flights are sorted by cheapest return flights first.

Deals found on 29/8

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from Panama City

Have a flexible travel schedule? Discover the best time to fly from Panama City with our price prediction graph.
Estimated return price

Travel insights for flights from Panama City

Get recent, data-driven insights about flights from Panama City including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Panama City?

Currently, March is the cheapest month in which you can book a flight from Panama City (average of £692). Flying from Panama City in January will prove the most costly (average of £946). There are multiple factors that influence the price of a flight so comparing airlines, departure airports and times can help keep costs down.

Which airlines fly from Panama City?

Many airlines operate round-trip flights from Panama City: Turkish Airlines, KLM. These airlines fly to the following popular destinations: London.

Copa Airlines
Copa Airlines
From £71
Turkish Airlines
Turkish Airlines
From £634
Air Panama
Air Panama
From £96
Air Europa
Air Europa
From £517

What are popular destinations to fly to from Panama City?

If you’re flying from Panama City, these routes are more frequently taken by airlines Miami (90 flights per day), Guatemala City (82 flights per day) and San José (74 flights per day).

Bogotá El Dorado
Bogotá El Dorado
From £171
Bocas Del Toro
Bocas Del Toro
From £49
New York
New York
From £618
Madrid Barajas
Madrid Barajas
From £487

What is the cheapest place to fly to from Panama City?

The cheapest city to fly to from Panama City is Bocas Del Toro, with prices starting at £49. Explore other affordable destinations below.

Bocas Del Toro
Bocas Del Toro
From £49
Cali Alfonso B. Aragon Intl
Cali Alfonso B. Aragon Intl
From £94
San José Juan Santamaria Intl
San José Juan Santamaria Intl
From £105
Bogotá El Dorado
Bogotá El Dorado
From £171

When is the best time to book a flight from Panama City?

Booking 77 days in advance of your planned departure date is, on average, the best time to get cheap flights from Panama City. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

Airline reviews for flights from Panama City

Read through reviews of airlines serving Panama City, such as KLM and Turkish Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7.8
Good
1,570 reviews
Check prices

Comfort

7.7

Crew

8.4

Entertainment

7.2

Food

7.3

Boarding

7.8

Overall

7.8

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
KLM
7.8
Good
1,570 reviews
KLM
7.8
Good
1,570 reviews
Check prices

Comfort

7.7

Crew

8.4

Entertainment

7.2

Food

7.3

Boarding

7.8

Overall

7.8

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
Turkish Airlines
7.4
Good
4,479 reviews
KLM
7.8
Good
1,570 reviews
Check prices

Comfort

7.7

Crew

8.4

Entertainment

7.2

Food

7.3

Boarding

7.8

Overall

7.8

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas

Browse thousands of different options on Cheapflights for your next trip

Direct flights from Panama

Direct flights from Panama City

Related info for your journey

  • What are the most popular destinations to fly to from Panama City?

    This month, the top selected destinations from Panama City are Bogotá, Cancún, Cartagena. Throughout the year, Bogotá, Bocas del Toro, Cancún are some of the top choices made by users flying from Panama City.

  • What is the cheapest flight from Panama City to anywhere?

    Users have flown out of Panama City for as low as £105 to San José (prices may vary depending on the airline and departure time). On average, users have booked flights for £439 to fly from Panama City.

  • What are the cheapest airlines flying from Panama City to anywhere?

    Over the past few days, we've found that Copa Airlines, Air Panama, and Avianca have the cheapest prices from Panama City. Copa Airlines flights from Panama City to David Enrique Malek (£71), Air Panama flights from Panama City to Bocas Del Toro (£96), and Avianca flights from Panama City to Bogotá El Dorado (£121).

  • What is the cheapest premium economy flight from Panama City?

    Here are some of the cheapest offers we have found for the cheapest premium economy flights from Panama City.
    Panama City Tocumen Intl to Paris Charles de Gaulle Airport from £965
    Panama City Tocumen Intl to Houston George Bush Intcntl Airport from £1,363
    Panama City Tocumen Intl to Amsterdam from £1,778

  • What is the cheapest month to fly from Panama City?

    At the present moment the cheapest month to fly from Panama City is currently March; with January being the most expensive. Prices will vary depending on multiple factors such as booking in advance, airline and departure airports and times.

  • Where are the cheapest places to fly to from Panama City?

    Check out the cheapest flights from Panama City to embark to:
    Travel from Panama City to London from £652 round trip

  • How does Cheapflights help users find flights from Panama City?

    Cheapflights makes it easy to find flights from Panama City by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

  • Why should you use Cheapflights to find cheap flight tickets from Panama City?

    Cheapflights taps into our reliable network of hundreds of airlines and travel agencies to find the best deals for flights from Panama City for you. Better yet — we are completely free to use.

  • Can Cheapflights find flights from Panama City with no change fees?

    Users can book flights with no change fees policies with our dedicated filters. Book flights from Panama City flexibly with Cheapflights today.

  • Can Cheapflights notify me if prices for flights from Panama City become cheaper?

    Yes, Cheapflights has a feature called Price Alerts, which offers users the ability to be notified when flight prices change. Track prices for your flight from Panama City today and book when you’re ready!

See more FAQs

Fly with Cheapflights

How does Cheapflights help users find flights from Panama City?

Cheapflights makes it easy to find flights from Panama City by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

Why should you use Cheapflights to find cheap flight tickets from Panama City?

Cheapflights taps into our reliable network of hundreds of airlines and travel agencies to find the best deals for flights from Panama City for you. Better yet — we are completely free to use.

Can Cheapflights find flights from Panama City with no change fees?

Users can book flights with no change fees policies with our dedicated filters. Book flights from Panama City flexibly with Cheapflights today.

Can Cheapflights notify me if prices for flights from Panama City become cheaper?

Yes, Cheapflights has a feature called Price Alerts, which offers users the ability to be notified when flight prices change. Track prices for your flight from Panama City today and book when you’re ready!

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