£117+ Cheap flights from Panama City
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 16/10. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
What to know about flights from Panama City
Discover essential information about flights departing from Panama City, including flight schedules, destinations, airlines operating at the Panama City airport, and any specific guidelines or requirements for travellers. Please note that the information is based on the most recent updates available. Data last updated 1 July 2025.
Cheapest one-way flight | £317 |
|---|---|
Cheapest airline | Copa Airlines |
Most popular destination | Istanbul (IST) |
Good round-trip deal | £142 or less |
Good one-way deal | £57 or less |
Find flights from Panama City
Cheapest flights from Panama CityExplore the most affordable flight options available from Panama City. Find the lowest fares based on data from user searches, with prices last updated on 1 July 2025.
Explore the most affordable flight options available from Panama City. Find the lowest fares based on data from user searches, with prices last updated on 1 July 2025.
Find flights from Panama City within your budget
Find flights departing from Panama City that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 1 July 2025. In the last 7 days, Cheapflights users made a total of 858,174 searches
Fly to
Route
Depart
Return
Price
Panama CityCúcuta
PTY - CUC
PTYCUC
Panama City Tocumen Intl
Sun 27/7
03:20-13:23
1 stop10h 03m
Cúcuta Camilo Dazo
Thu 28/8
16:38-21:10
1 stop4h 32m
Panama CityCúcuta
PTY - CUC
PTYCUC
Panama City Tocumen Intl
Fri 25/7
11:36-13:15
Nonstop1h 39m
Cúcuta Camilo Dazo
Sat 2/8
15:01-16:49
Nonstop1h 48m
Panama CityBrussels
PTY - BRU
PTYBRU
Panama City Tocumen Intl
Fri 12/9
21:55-13:25
1 stop32h 30m
Brussels Bruxelles-National
Fri 26/9
07:15-20:00
1 stop19h 45m
Panama CityDüsseldorf
PTY - DUS
PTYDUS
Panama City Tocumen Intl
Sun 3/8
21:55-13:25
1 stop32h 30m
Duesseldorf Intl
Sun 24/8
07:20-20:00
1 stop19h 40m
Panama CityBrussels
PTY - BRU
PTYBRU
Panama City Tocumen Intl
Thu 25/12
18:45-07:35
1 stop30h 50m
Brussels Bruxelles-National
Mon 12/1
10:45-16:25
1 stop35h 40m
Panama CityLondon
PTY - LHR
PTYLHR
Panama City Tocumen Intl
Thu 27/11
18:45-21:05
1 stop21h 20m
London Heathrow
Tue 2/12
22:35-19:50
1 stop26h 15m
Panama CityLondon
PTY - LHR
PTYLHR
Panama City Tocumen Intl
Wed 30/7
14:28-11:10
1 stop14h 42m
London Heathrow
Sat 16/8
14:45-16:50
1 stop32h 05m
Panama CityLondon
PTY - LGW
PTYLGW
Panama City Tocumen Intl
Thu 27/11
18:45-09:10
1 stop33h 25m
London Gatwick
Tue 2/12
10:05-17:05
2 stops36h 00m
Panama CityLondon
PTY - LGW
PTYLGW
Panama City Tocumen Intl
Sat 16/8
22:05-06:55
2 stops26h 50m
London Gatwick
Fri 29/8
10:00-00:45
2 stops20h 45m
Panama CityLondon
PTY - LHR
PTYLHR
Panama City Tocumen Intl
Wed 24/12
15:20-10:35
1 stop14h 15m
London Heathrow
Mon 26/1
11:30-20:10
1 stop13h 40m
Best time to book a flight from Panama City
Have a flexible travel schedule? Discover the best time to fly from Panama City with our price prediction graph.
Travel insights for flights from Panama City
Get recent, data-driven insights about flights from Panama City including ideal travel times, pricing trends, and more.
When is the best time to book a flight from Panama City?
Use this chart to determine the optimal time to book a return flight from Panama City to Heathrow. Price data was last updated on 27 June 2025.
Booking 35 days in advance of your planned departure date is, on average, the best time to get cheap flights from Panama City. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from Panama City?
Currently, December is the cheapest month in which you can book a flight from Panama City (average of £479). Flying from Panama City in June will prove the most costly (average of £704). There are multiple factors that influence the price of a flight so comparing airlines, departure airports and times can help keep costs down.
Which airlines fly from Panama City?
Many airlines operate round-trip flights from Panama City: Air France, United Airlines, KLM. These airlines fly to the following popular destinations: London.
What are popular destinations to fly to from Panama City?
If you’re flying from Panama City, these routes are more frequently taken by airlines New York (160 flights per day), Orlando (138 flights per day) and San José (133 flights per day).
What is the cheapest place to fly to from Panama City?
The cheapest city to fly to from Panama City is Bocas Del Toro, with prices starting at £57. Explore other affordable destinations below.
Airline reviews for flights from Panama City
Get insights into the airlines that provide service from Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing airline for your flight from Panama City. In the last 7 days, Cheapflights users made a total of 858,174 searches.
Read through reviews of airlines serving Panama City, such as KLM, Air France, andUnited Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
Crew
Entertainment
Overall
Boarding
Comfort
Reviews
Anonymous,Jun 2025
AMS - BOS
Food
Crew
Entertainment
Overall
Boarding
Comfort
Reviews
Anonymous,Jun 2025
AMS - BOS
Food
Crew
Entertainment
Overall
Boarding
Comfort
Reviews
Anonymous,Jun 2025
AMS - BOS
Food
Crew
Entertainment
Overall
Boarding
Comfort
Reviews
Anonymous,Jun 2025
AMS - BOS
Food
Crew
Entertainment
Overall
Boarding
Comfort
Reviews
Anonymous,Jun 2025
AMS - BOS
Food
Crew
Entertainment
Overall
Boarding
Comfort
Reviews
Anonymous,Jun 2025
AMS - BOS
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Direct flights from Panama
Book a direct flight from one of these other cities located in Panama.
Related info for your journey
Access useful and relevant information related to your journey from Panama City. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 1 July 2025.
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How does Cheapflights help users find flights from Panama City?
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Users can book flights with no change fees policies with our dedicated filters. Book flights from Panama City flexibly with Cheapflights today.
Can Cheapflights notify me if prices for flights from Panama City become cheaper?
Yes, Cheapflights has a feature called Price Alerts, which offers users the ability to be notified when flight prices change. Track prices for your flight from Panama City today and book when you’re ready!