Out of all the popular cities in Chile, Santiago is the cheapest city to hire a car in at just £19/day. Renting a car in Santiago is 76% cheaper than renting one in Balmaceda where the per day rate is around £74. Other fairly inexpensive cities in Chile to get a car hire in are: Antofagasta (£23/day), Calama (£31/day), and La Serena (£33/day). While these cities typically have cheaper prices than the rest of the country, travellers looking to hire a car in Santiago should expect to spend around £19/day on their transportation. The most popular city to rent a car in Chile is Santiago.