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£147+ Direct flights from St. Louis

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 25/2. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
STL — LHR
27 Jan — 3 Feb1
1 adult
1 adult, Economy, 0 bags

Direct flights from St. Louis

Enter your travel dates to find the best prices.

Cheapest flights from St. Louis
Explore the most affordable flight options available from St. Louis. Find the lowest fares based on data from user searches, with prices last updated on 28 December 2025.

Sun 25/105:00STL - LAS
Nonstop3h 40mSouthwest
Sun 1/218:40LAS - STL
Nonstop3h 05mSouthwest
Deal found 26/12£161
Sat 24/117:50STL - LAS
Nonstop3h 45mSouthwest
Sat 31/106:40LAS - STL
Nonstop3h 05mSouthwest
Deal found 26/12£168
Wed 28/119:45STL - LAS
Nonstop3h 45mSouthwest
Sun 1/206:35LAS - STL
Nonstop3h 05mSouthwest
Deal found 26/12£227
Sat 17/117:50STL - LAS
Nonstop3h 45mSouthwest
Wed 21/106:35LAS - STL
Nonstop3h 05mSouthwest
Deal found 26/12£235
Mon 26/106:00STL - LAS
Nonstop3h 45mSouthwest
Sat 31/106:40LAS - STL
Nonstop3h 05mSouthwest
Deal found 25/12£240
Fri 13/219:55STL - LAS
Nonstop3h 45mSouthwest
Sun 15/218:40LAS - STL
Nonstop3h 05mSouthwest
Deal found 26/12£255
Fri 23/116:20STL - LAS
Nonstop3h 50mSouthwest
Fri 30/117:15LAS - STL
Nonstop3h 05mSouthwest
Deal found 26/12£278
Sat 17/117:50STL - LAS
Nonstop3h 45mSouthwest
Mon 19/118:40LAS - STL
Nonstop3h 05mSouthwest
Deal found 25/12£285
Wed 21/114:50STL - LAS
Nonstop3h 45mSouthwest
Wed 28/117:15LAS - STL
Nonstop3h 05mSouthwest
Deal found 27/12£294
Tue 20/119:45STL - LAS
Nonstop3h 45mSouthwest
Sat 24/106:40LAS - STL
Nonstop3h 05mSouthwest
Deal found 25/12£307
Sat 10/114:45STL - LAS
Nonstop3h 45mSouthwest
Sat 17/111:45LAS - STL
Nonstop3h 10mSouthwest
Deal found 26/12£316
Wed 11/206:00STL - LAS
Nonstop3h 45mSouthwest
Sun 15/208:45LAS - STL
Nonstop3h 10mSouthwest
Deal found 26/12£322

Find direct flights from St. Louis within your budget

 
Use the slider to find direct flights from St. Louis within your budget. Price data is based on user searches made on Cheapflights. Over the past seven days, Cheapflights users made 858,174 searches. This data was last updated on 28 December 2025.

Fly to

Heathrow

Route

Depart

Return

Price

St. LouisLas Vegas

STL - LAS

STLLAS

Lambert-St Louis

Sun 25/1

05:00-06:40

Nonstop3h 40m

Las Vegas Harry Reid Intl

Sun 1/2

18:40-23:45

Nonstop3h 05m

£161

St. LouisLas Vegas

STL - LAS

STLLAS

Lambert-St Louis

Sat 7/2

17:50-19:35

Nonstop3h 45m

Las Vegas Harry Reid Intl

Thu 12/2

07:35-12:40

Nonstop3h 05m

£161

St. LouisLas Vegas

STL - LAS

STLLAS

Lambert-St Louis

Sat 24/1

17:50-19:35

Nonstop3h 45m

Las Vegas Harry Reid Intl

Sat 31/1

06:40-11:45

Nonstop3h 05m

£168

St. LouisLas Vegas

STL - LAS

STLLAS

Lambert-St Louis

Sun 8/2

14:50-16:35

Nonstop3h 45m

Las Vegas Harry Reid Intl

Wed 11/2

17:15-22:20

Nonstop3h 05m

£227

St. LouisLas Vegas

STL - LAS

STLLAS

Lambert-St Louis

Mon 2/3

20:50-22:35

Nonstop3h 45m

Las Vegas Harry Reid Intl

Wed 4/3

17:15-22:20

Nonstop3h 05m

£227

St. LouisLas Vegas

STL - LAS

STLLAS

Lambert-St Louis

Sun 1/2

05:00-06:40

Nonstop3h 40m

Las Vegas Harry Reid Intl

Wed 4/2

06:35-11:40

Nonstop3h 05m

£227

St. LouisLas Vegas

STL - LAS

STLLAS

Lambert-St Louis

Wed 28/1

19:45-21:30

Nonstop3h 45m

Las Vegas Harry Reid Intl

Sun 1/2

06:35-11:40

Nonstop3h 05m

£227

St. LouisLas Vegas

STL - LAS

STLLAS

Lambert-St Louis

Mon 2/2

06:00-07:45

Nonstop3h 45m

Las Vegas Harry Reid Intl

Wed 4/2

06:35-11:40

Nonstop3h 05m

£227

St. LouisLas Vegas

STL - LAS

STLLAS

Lambert-St Louis

Wed 21/1

14:50-16:35

Nonstop3h 45m

Las Vegas Harry Reid Intl

Mon 26/1

06:35-11:40

Nonstop3h 05m

£227

St. LouisLas Vegas

STL - LAS

STLLAS

Lambert-St Louis

Wed 18/2

19:45-21:30

Nonstop3h 45m

Las Vegas Harry Reid Intl

Mon 23/2

18:40-23:45

Nonstop3h 05m

£227

Flights are sorted by cheapest return flights first.

Deals found on 26/12

Showing 1-10 of 39 results
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Best time to book a flight from St. Louis

Have a flexible travel schedule? Discover the best time to fly from St. Louis with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines flying non-stop to St. Louis

Get insights into the airlines that provide direct flights from St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight from St. Louis. Reviews last updated Cheapflights.
Read through reviews of airlines serving St. Louis, such as Virgin Atlantic, Air Canada, andBritish Airways. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Virgin Atlantic
7.5
Good
677 reviews
Check prices

Overall

7.5

Crew

8.1

Entertainment

7.6

Food

6.9

Boarding

7.7

Comfort

7.3

Reviews

1 / 20
6.0
Good

Pratap,Aug 2025

JFK - LHR

The flight is clean, food good and the staff are excellent! Very professional, polite and accommodating. The seat itself is really mediocre. Can’t believe there is not inch of storage space. Believe it or not it there is not place even to put away your phone or pen!! Very very surprising and terribly inconvenient. No coat hanger hook either. Had to give it away. ALL IN ALL VERY INCONVENIENT business class seat compared to their peers. What is even more surprising is that this on their relatively new fleet of Airbus A350-1000. I was having com platelets different expectations of Virgin and this has disappointed me. Everything else is just as good and as you would expect from Virgin!
Virgin Atlantic
7.5
Good
677 reviews
Virgin Atlantic
7.5
Good
677 reviews
Check prices

Overall

7.5

Crew

8.1

Entertainment

7.6

Food

6.9

Boarding

7.7

Comfort

7.3

Reviews

1 / 20
6.0
Good

Pratap,Aug 2025

JFK - LHR

The flight is clean, food good and the staff are excellent! Very professional, polite and accommodating. The seat itself is really mediocre. Can’t believe there is not inch of storage space. Believe it or not it there is not place even to put away your phone or pen!! Very very surprising and terribly inconvenient. No coat hanger hook either. Had to give it away. ALL IN ALL VERY INCONVENIENT business class seat compared to their peers. What is even more surprising is that this on their relatively new fleet of Airbus A350-1000. I was having com platelets different expectations of Virgin and this has disappointed me. Everything else is just as good and as you would expect from Virgin!
Air Canada
7.1
Good
10,562 reviews
Virgin Atlantic
7.5
Good
677 reviews
Check prices

Overall

7.5

Crew

8.1

Entertainment

7.6

Food

6.9

Boarding

7.7

Comfort

7.3

Reviews

1 / 20
6.0
Good

Pratap,Aug 2025

JFK - LHR

The flight is clean, food good and the staff are excellent! Very professional, polite and accommodating. The seat itself is really mediocre. Can’t believe there is not inch of storage space. Believe it or not it there is not place even to put away your phone or pen!! Very very surprising and terribly inconvenient. No coat hanger hook either. Had to give it away. ALL IN ALL VERY INCONVENIENT business class seat compared to their peers. What is even more surprising is that this on their relatively new fleet of Airbus A350-1000. I was having com platelets different expectations of Virgin and this has disappointed me. Everything else is just as good and as you would expect from Virgin!
British Airways
6.7
Okay
7,616 reviews
Virgin Atlantic
7.5
Good
677 reviews
Check prices

Overall

7.5

Crew

8.1

Entertainment

7.6

Food

6.9

Boarding

7.7

Comfort

7.3

Reviews

1 / 20
6.0
Good

Pratap,Aug 2025

JFK - LHR

The flight is clean, food good and the staff are excellent! Very professional, polite and accommodating. The seat itself is really mediocre. Can’t believe there is not inch of storage space. Believe it or not it there is not place even to put away your phone or pen!! Very very surprising and terribly inconvenient. No coat hanger hook either. Had to give it away. ALL IN ALL VERY INCONVENIENT business class seat compared to their peers. What is even more surprising is that this on their relatively new fleet of Airbus A350-1000. I was having com platelets different expectations of Virgin and this has disappointed me. Everything else is just as good and as you would expect from Virgin!

Related info for your journey

Access useful and relevant information related to your journey from St. Louis. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 28 December 2025.

  • Where can you fly direct from St. Louis?

    Currently, the most popular direct flight destination from St. Louis is Tampa.

  • What is the best time of year to fly direct from St. Louis?

    If you're seeking the lowest price on a direct flight from St. Louis, October is worth consideration as prices are at their lowest, on average. In terms of the number of daily non-stop flights, September offers travelers the most options.

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