Find flights
Airlines

£323+ Direct flights from St. Louis

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/5. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
STL — LHR
27 Feb — 6 Mar1
1 adult
1 adult, Economy, 0 bags

Direct flights from St. Louis

Enter your travel dates to find the best prices.

Cheapest flights from St. Louis
Explore the most affordable flight options available from St. Louis. Find the lowest fares based on data from user searches, with prices last updated on 28 January 2026.

Sun 3/521:40
STL
-
LHR
Nonstop8h 00m
British Airways
Wed 13/516:25
LHR
-
STL
Nonstop9h 05m
British Airways
Deal found 27/1£489
Tue 28/421:35
STL
-
LHR
Nonstop8h 00m
British Airways
Wed 13/516:25
LHR
-
STL
Nonstop9h 05m
British Airways
Deal found 27/1£507
Tue 5/521:35
STL
-
LHR
Nonstop8h 00m
British Airways
Tue 19/516:25
LHR
-
STL
Nonstop9h 05m
British Airways
Deal found 25/1£515
Wed 29/421:35
STL
-
LHR
Nonstop8h 00m
British Airways
Wed 13/516:25
LHR
-
STL
Nonstop9h 05m
British Airways
Deal found 27/1£531
Tue 5/521:35
STL
-
LHR
Nonstop8h 00m
British Airways
Tue 12/516:25
LHR
-
STL
Nonstop9h 05m
British Airways
Deal found 26/1£539
Sun 26/421:40
STL
-
LHR
Nonstop8h 00m
British Airways
Sun 3/516:25
LHR
-
STL
Nonstop9h 05m
British Airways
Deal found 27/1£544
Tue 28/421:35
STL
-
LHR
Nonstop8h 00m
Iberia
Tue 5/516:25
LHR
-
STL
Nonstop9h 05m
Iberia
Deal found 26/1£547
Tue 28/421:35
STL
-
LHR
Nonstop8h 00m
British Airways
Fri 8/516:25
LHR
-
STL
Nonstop9h 05m
British Airways
Deal found 27/1£550
Tue 28/421:35
STL
-
LHR
Nonstop8h 00m
British Airways
Sun 3/516:25
LHR
-
STL
Nonstop9h 05m
British Airways
Deal found 27/1£562
Wed 29/421:35
STL
-
LHR
Nonstop8h 00m
British Airways
Fri 8/516:25
LHR
-
STL
Nonstop9h 05m
British Airways
Deal found 27/1£573
Fri 1/521:35
STL
-
LHR
Nonstop8h 00m
British Airways
Wed 13/516:25
LHR
-
STL
Nonstop9h 05m
British Airways
Deal found 27/1£595

Find direct flights from St. Louis within your budget

 
Use the slider to find direct flights from St. Louis within your budget. Price data is based on user searches made on Cheapflights. Over the past seven days, Cheapflights users made 858,174 searches. This data was last updated on 28 January 2026.

Fly to

Heathrow

Route

Depart

Return

Price

St. LouisLondon

STL - LHR

STLLHR

Lambert-St Louis

Wed 29/4

21:35-11:35

Nonstop8h 00m

London Heathrow

Wed 13/5

16:25-19:30

Nonstop9h 05m

£531

St. LouisLondon

STL - LHR

STLLHR

Lambert-St Louis

Sun 3/5

21:40-11:40

Nonstop8h 00m

London Heathrow

Tue 12/5

16:25-19:30

Nonstop9h 05m

£531

St. LouisLondon

STL - LHR

STLLHR

Lambert-St Louis

Tue 5/5

21:35-11:35

Nonstop8h 00m

London Heathrow

Tue 19/5

16:25-19:30

Nonstop9h 05m

£542

St. LouisLondon

STL - LHR

STLLHR

Lambert-St Louis

Fri 8/5

21:35-11:35

Nonstop8h 00m

London Heathrow

Fri 15/5

16:25-19:30

Nonstop9h 05m

£544

St. LouisLondon

STL - LHR

STLLHR

Lambert-St Louis

Tue 28/4

21:35-11:35

Nonstop8h 00m

London Heathrow

Fri 8/5

16:25-19:30

Nonstop9h 05m

£550

St. LouisLondon

STL - LHR

STLLHR

Lambert-St Louis

Tue 21/4

21:35-11:35

Nonstop8h 00m

London Heathrow

Wed 29/4

16:25-19:30

Nonstop9h 05m

£558

St. LouisLondon

STL - LHR

STLLHR

Lambert-St Louis

Wed 29/4

21:35-11:35

Nonstop8h 00m

London Heathrow

Wed 6/5

16:25-19:30

Nonstop9h 05m

£573

St. LouisLondon

STL - LHR

STLLHR

Lambert-St Louis

Wed 29/4

21:35-11:35

Nonstop8h 00m

London Heathrow

Fri 8/5

16:25-19:30

Nonstop9h 05m

£573

St. LouisLondon

STL - LHR

STLLHR

Lambert-St Louis

Tue 28/4

21:35-11:35

Nonstop8h 00m

London Heathrow

Tue 5/5

16:25-19:30

Nonstop9h 05m

£577

St. LouisLondon

STL - LHR

STLLHR

Lambert-St Louis

Tue 21/4

21:35-11:35

Nonstop8h 00m

London Heathrow

Sun 26/4

16:25-19:30

Nonstop9h 05m

£595

Flights are sorted by cheapest return flights first.

Deals found on 27/1

Showing 1-10 of 21 results
1
2
3

Best time to book a flight from St. Louis

Have a flexible travel schedule? Discover the best time to fly from St. Louis with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines flying non-stop to St. Louis

Get insights into the airlines that provide direct flights from St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight from St. Louis. Reviews last updated Cheapflights.
Read through reviews of airlines serving St. Louis, such as Virgin Atlantic, American Airlines, andAir Canada. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Virgin Atlantic
7.5
Good
678 reviews
Check prices

Boarding

7.7

Food

6.9

Overall

7.5

Comfort

7.3

Crew

8.2

Entertainment

7.6

Reviews

1 / 20
6.0
Good

Pratap,Aug 2025

JFK - LHR

The flight is clean, food good and the staff are excellent! Very professional, polite and accommodating. The seat itself is really mediocre. Can’t believe there is not inch of storage space. Believe it or not it there is not place even to put away your phone or pen!! Very very surprising and terribly inconvenient. No coat hanger hook either. Had to give it away. ALL IN ALL VERY INCONVENIENT business class seat compared to their peers. What is even more surprising is that this on their relatively new fleet of Airbus A350-1000. I was having com platelets different expectations of Virgin and this has disappointed me. Everything else is just as good and as you would expect from Virgin!
Virgin Atlantic
7.5
Good
678 reviews
Virgin Atlantic
7.5
Good
678 reviews
Check prices

Boarding

7.7

Food

6.9

Overall

7.5

Comfort

7.3

Crew

8.2

Entertainment

7.6

Reviews

1 / 20
6.0
Good

Pratap,Aug 2025

JFK - LHR

The flight is clean, food good and the staff are excellent! Very professional, polite and accommodating. The seat itself is really mediocre. Can’t believe there is not inch of storage space. Believe it or not it there is not place even to put away your phone or pen!! Very very surprising and terribly inconvenient. No coat hanger hook either. Had to give it away. ALL IN ALL VERY INCONVENIENT business class seat compared to their peers. What is even more surprising is that this on their relatively new fleet of Airbus A350-1000. I was having com platelets different expectations of Virgin and this has disappointed me. Everything else is just as good and as you would expect from Virgin!
American Airlines
7.2
Good
11,201 reviews
Virgin Atlantic
7.5
Good
678 reviews
Check prices

Boarding

7.7

Food

6.9

Overall

7.5

Comfort

7.3

Crew

8.2

Entertainment

7.6

Reviews

1 / 20
6.0
Good

Pratap,Aug 2025

JFK - LHR

The flight is clean, food good and the staff are excellent! Very professional, polite and accommodating. The seat itself is really mediocre. Can’t believe there is not inch of storage space. Believe it or not it there is not place even to put away your phone or pen!! Very very surprising and terribly inconvenient. No coat hanger hook either. Had to give it away. ALL IN ALL VERY INCONVENIENT business class seat compared to their peers. What is even more surprising is that this on their relatively new fleet of Airbus A350-1000. I was having com platelets different expectations of Virgin and this has disappointed me. Everything else is just as good and as you would expect from Virgin!
Air Canada
7.1
Good
10,666 reviews
Virgin Atlantic
7.5
Good
678 reviews
Check prices

Boarding

7.7

Food

6.9

Overall

7.5

Comfort

7.3

Crew

8.2

Entertainment

7.6

Reviews

1 / 20
6.0
Good

Pratap,Aug 2025

JFK - LHR

The flight is clean, food good and the staff are excellent! Very professional, polite and accommodating. The seat itself is really mediocre. Can’t believe there is not inch of storage space. Believe it or not it there is not place even to put away your phone or pen!! Very very surprising and terribly inconvenient. No coat hanger hook either. Had to give it away. ALL IN ALL VERY INCONVENIENT business class seat compared to their peers. What is even more surprising is that this on their relatively new fleet of Airbus A350-1000. I was having com platelets different expectations of Virgin and this has disappointed me. Everything else is just as good and as you would expect from Virgin!
British Airways
6.7
Okay
7,704 reviews
Virgin Atlantic
7.5
Good
678 reviews
Check prices

Boarding

7.7

Food

6.9

Overall

7.5

Comfort

7.3

Crew

8.2

Entertainment

7.6

Reviews

1 / 20
6.0
Good

Pratap,Aug 2025

JFK - LHR

The flight is clean, food good and the staff are excellent! Very professional, polite and accommodating. The seat itself is really mediocre. Can’t believe there is not inch of storage space. Believe it or not it there is not place even to put away your phone or pen!! Very very surprising and terribly inconvenient. No coat hanger hook either. Had to give it away. ALL IN ALL VERY INCONVENIENT business class seat compared to their peers. What is even more surprising is that this on their relatively new fleet of Airbus A350-1000. I was having com platelets different expectations of Virgin and this has disappointed me. Everything else is just as good and as you would expect from Virgin!

Related info for your journey

Access useful and relevant information related to your journey from St. Louis. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 28 January 2026.

  • Where can you fly direct from St. Louis?

    Currently, the most popular direct flight destination from St. Louis is Salt Lake City.

  • What is the best time of year to fly direct from St. Louis?

    If you're seeking the lowest price on a direct flight from St. Louis, October is worth consideration as prices are at their lowest, on average. In terms of the number of daily non-stop flights, November offers travelers the most options.

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Direct flights from Missouri cities

Book a direc flight from one of these other cities located in Missouri.
Direct flights from Kansas City
Direct flights from Columbia

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.