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£93+ Direct flights from St. Louis

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/12. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
STL — LHR
7 Dec — 14 Dec1
1 adult
1 adult, Economy, 0 bags

Direct flights from St. Louis

Enter your travel dates to find the best prices.

Cheapest flights from St. Louis
Explore the most affordable flight options available from St. Louis. Find the lowest fares based on data from user searches, with prices last updated on 7 November 2025.

Thu 27/1110:00STL - LAX
Nonstop4h 10mSouthwest
Sat 6/1207:10LAX - STL
Nonstop3h 35mSouthwest
Deal found 5/11£225
Fri 5/1218:35STL - LAX
Nonstop4h 05mSouthwest
Tue 9/1214:15LAX - STL
Nonstop3h 30mSouthwest
Deal found 6/11£226
Thu 4/1218:35STL - LAX
Nonstop4h 05mSouthwest
Thu 11/1214:15LAX - STL
Nonstop3h 30mSouthwest
Deal found 7/11£227
Tue 9/1210:15STL - LAX
Nonstop4h 10mSouthwest
Sun 14/1205:00LAX - STL
Nonstop3h 40mSouthwest
Deal found 5/11£237
Fri 16/119:45STL - LAX
Nonstop4h 15mSouthwest
Mon 19/105:50LAX - STL
Nonstop3h 40mSouthwest
Deal found 6/11£238
Mon 8/1218:35STL - LAX
Nonstop4h 05mSouthwest
Fri 16/105:50LAX - STL
Nonstop3h 40mSouthwest
Deal found 5/11£248
Wed 3/1218:35STL - LAX
Nonstop4h 05mSouthwest
Wed 10/1207:35LAX - STL
Nonstop3h 35mSouthwest
Deal found 5/11£251
Mon 24/1105:45STL - LAX
Nonstop4h 10mSouthwest
Tue 2/1214:15LAX - STL
Nonstop3h 30mSouthwest
Deal found 5/11£256
Tue 25/1106:00STL - LAX
Nonstop4h 10mSouthwest
Sat 29/1105:05LAX - STL
Nonstop3h 40mSouthwest
Deal found 7/11£257
Thu 4/1218:35STL - LAX
Nonstop4h 05mSouthwest
Mon 8/1207:35LAX - STL
Nonstop3h 35mSouthwest
Deal found 6/11£270
Tue 9/1218:35STL - LAX
Nonstop4h 05mSouthwest
Fri 12/1210:35LAX - STL
Nonstop3h 35mSouthwest
Deal found 6/11£273
Fri 5/1218:35STL - LAX
Nonstop4h 05mSouthwest
Fri 12/1210:35LAX - STL
Nonstop3h 35mSouthwest
Deal found 6/11£273

Find direct flights from St. Louis within your budget

 
Use the slider to find direct flights from St. Louis within your budget. Price data is based on user searches made on Cheapflights. Over the past seven days, Cheapflights users made 858,174 searches. This data was last updated on 7 November 2025.

Fly to

Heathrow

Route

Depart

Return

Price

St. LouisLos Angeles

STL - LAX

STLLAX

Lambert-St Louis

Wed 10/12

18:35-20:40

Nonstop4h 05m

Los Angeles

Tue 16/12

14:15-19:45

Nonstop3h 30m

£225

St. LouisLos Angeles

STL - LAX

STLLAX

Lambert-St Louis

Fri 5/12

18:35-20:40

Nonstop4h 05m

Los Angeles

Tue 9/12

14:15-19:45

Nonstop3h 30m

£226

St. LouisLos Angeles

STL - LAX

STLLAX

Lambert-St Louis

Fri 6/2

19:45-22:00

Nonstop4h 15m

Los Angeles

Mon 9/2

05:50-11:30

Nonstop3h 40m

£227

St. LouisLos Angeles

STL - LAX

STLLAX

Lambert-St Louis

Fri 12/12

05:45-07:55

Nonstop4h 10m

Los Angeles

Sun 14/12

05:00-10:40

Nonstop3h 40m

£227

St. LouisLos Angeles

STL - LAX

STLLAX

Lambert-St Louis

Fri 16/1

19:45-22:00

Nonstop4h 15m

Los Angeles

Tue 20/1

11:35-17:10

Nonstop3h 35m

£237

St. LouisLos Angeles

STL - LAX

STLLAX

Lambert-St Louis

Fri 12/12

21:15-23:25

Nonstop4h 10m

Los Angeles

Tue 16/12

07:35-13:10

Nonstop3h 35m

£237

St. LouisLos Angeles

STL - LAX

STLLAX

Lambert-St Louis

Tue 23/12

06:00-08:10

Nonstop4h 10m

Los Angeles

Tue 30/12

09:00-14:45

Nonstop3h 45m

£237

St. LouisLos Angeles

STL - LAX

STLLAX

Lambert-St Louis

Wed 21/1

10:25-12:45

Nonstop4h 20m

Los Angeles

Sun 25/1

05:50-11:30

Nonstop3h 40m

£238

St. LouisLos Angeles

STL - LAX

STLLAX

Lambert-St Louis

Mon 8/12

10:15-12:25

Nonstop4h 10m

Los Angeles

Thu 15/1

05:50-11:30

Nonstop3h 40m

£248

St. LouisLos Angeles

STL - LAX

STLLAX

Lambert-St Louis

Sun 21/12

06:00-08:10

Nonstop4h 10m

Los Angeles

Sun 28/12

05:10-10:50

Nonstop3h 40m

£248

Flights are sorted by cheapest return flights first.

Deals found on 5/11

Showing 1-10 of 37 results
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Best time to book a flight from St. Louis

Have a flexible travel schedule? Discover the best time to fly from St. Louis with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines flying non-stop to St. Louis

Get insights into the airlines that provide direct flights from St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight from St. Louis. Reviews last updated Cheapflights.
Read through reviews of airlines serving St. Louis, such as KLM, Virgin Atlantic, andAir Canada. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7.7
Good
1,408 reviews
Check prices

Entertainment

7.1

Comfort

7.7

Boarding

7.8

Food

7.3

Crew

8.4

Overall

7.7

Reviews

1 / 20
2.0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.
KLM
7.7
Good
1,408 reviews
KLM
7.7
Good
1,408 reviews
Check prices

Entertainment

7.1

Comfort

7.7

Boarding

7.8

Food

7.3

Crew

8.4

Overall

7.7

Reviews

1 / 20
2.0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.
Virgin Atlantic
7.5
Good
672 reviews
KLM
7.7
Good
1,408 reviews
Check prices

Entertainment

7.1

Comfort

7.7

Boarding

7.8

Food

7.3

Crew

8.4

Overall

7.7

Reviews

1 / 20
2.0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.
Air Canada
7.1
Good
10,416 reviews
KLM
7.7
Good
1,408 reviews
Check prices

Entertainment

7.1

Comfort

7.7

Boarding

7.8

Food

7.3

Crew

8.4

Overall

7.7

Reviews

1 / 20
2.0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.
British Airways
6.7
Okay
7,500 reviews
KLM
7.7
Good
1,408 reviews
Check prices

Entertainment

7.1

Comfort

7.7

Boarding

7.8

Food

7.3

Crew

8.4

Overall

7.7

Reviews

1 / 20
2.0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.

Related info for your journey

Access useful and relevant information related to your journey from St. Louis. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 7 November 2025.

  • Where can you fly direct from St. Louis?

    Currently, the most popular direct flight destination from St. Louis is San Francisco.

  • How much are direct flights from St. Louis?

    On average, a one-way direct flight from St. Louis will cost users approximately £153. If you're looking for a direct round-trip flight from St. Louis, you can expect to pay around £294.

  • How long is a direct flight from St. Louis?

    While the flight duration depends heavily on the destination, on average, travelers can expect non-stop flights from St. Louis to last approximately 5h 09m on average. The quickest direct flight from St. Louis at this time departs from St. Louis (3h 45m), while the longest leaves from St. Louis (8h 05m).

  • What is the best time of year to fly direct from St. Louis?

    If you're seeking the lowest price on a direct flight from St. Louis, October is worth consideration as prices are at their lowest, on average. In terms of the number of daily non-stop flights, April offers travelers the most options.

See more FAQs

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