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£315+ Direct flights from St. Louis

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 22/4. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
STL — LHR
20 Feb — 27 Feb1
1 adult
1 adult, Economy, 0 bags

Direct flights from St. Louis

Enter your travel dates to find the best prices.

Cheapest flights from St. Louis
Explore the most affordable flight options available from St. Louis. Find the lowest fares based on data from user searches, with prices last updated on 21 January 2026.

Sun 26/421:40
STL
-
LHR
Nonstop8h 00m
British Airways
Sun 3/516:25
LHR
-
STL
Nonstop9h 05m
British Airways
Deal found 19/1£480
Tue 28/421:35
STL
-
LHR
Nonstop8h 00m
British Airways
Fri 8/516:25
LHR
-
STL
Nonstop9h 05m
British Airways
Deal found 19/1£505
Fri 24/421:35
STL
-
LHR
Nonstop8h 00m
British Airways
Wed 29/416:25
LHR
-
STL
Nonstop9h 05m
British Airways
Deal found 18/1£526
Fri 24/421:35
STL
-
LHR
Nonstop8h 00m
British Airways
Sun 26/416:25
LHR
-
STL
Nonstop9h 05m
British Airways
Deal found 18/1£564
Tue 5/521:35
STL
-
LHR
Nonstop8h 00m
British Airways
Tue 19/516:25
LHR
-
STL
Nonstop9h 05m
British Airways
Deal found 20/1£573
Tue 21/421:35
STL
-
LHR
Nonstop8h 00m
Iberia
Tue 12/516:25
LHR
-
STL
Nonstop9h 05m
Iberia
Deal found 21/1£610
Sun 3/521:40
STL
-
LHR
Nonstop8h 00m
Finnair
Wed 6/516:25
LHR
-
STL
Nonstop9h 05m
Finnair
Deal found 19/1£612
Fri 24/421:35
STL
-
LHR
Nonstop8h 00m
British Airways
Sun 3/516:25
LHR
-
STL
Nonstop9h 05m
British Airways
Deal found 19/1£616
Wed 6/521:35
STL
-
LHR
Nonstop8h 00m
American Airlines
Sun 10/516:25
LHR
-
STL
Nonstop9h 05m
American Airlines
Deal found 19/1£624
Sun 3/521:40
STL
-
LHR
Nonstop8h 00m
British Airways
Wed 6/516:25
LHR
-
STL
Nonstop9h 05m
British Airways
Deal found 20/1£628
Sun 26/421:40
STL
-
LHR
Nonstop8h 00m
British Airways
Fri 1/516:25
LHR
-
STL
Nonstop9h 05m
British Airways
Deal found 18/1£634
Tue 21/421:35
STL
-
LHR
Nonstop8h 00m
British Airways
Fri 24/416:25
LHR
-
STL
Nonstop9h 05m
British Airways
Deal found 18/1£639

Find direct flights from St. Louis within your budget

 
Use the slider to find direct flights from St. Louis within your budget. Price data is based on user searches made on Cheapflights. Over the past seven days, Cheapflights users made 858,174 searches. This data was last updated on 21 January 2026.

Fly to

Heathrow

Route

Depart

Return

Price

St. LouisLondon

STL - LHR

STLLHR

Lambert-St Louis

Sun 26/4

21:40-11:40

Nonstop8h 00m

London Heathrow

Sun 3/5

16:25-19:30

Nonstop9h 05m

£480

St. LouisLondon

STL - LHR

STLLHR

Lambert-St Louis

Fri 24/4

21:35-11:35

Nonstop8h 00m

London Heathrow

Tue 28/4

16:25-19:30

Nonstop9h 05m

£526

St. LouisLondon

STL - LHR

STLLHR

Lambert-St Louis

Tue 5/5

21:35-11:35

Nonstop8h 00m

London Heathrow

Tue 19/5

16:25-19:30

Nonstop9h 05m

£526

St. LouisLondon

STL - LHR

STLLHR

Lambert-St Louis

Fri 24/4

21:35-11:35

Nonstop8h 00m

London Heathrow

Wed 29/4

16:25-19:30

Nonstop9h 05m

£526

St. LouisLondon

STL - LHR

STLLHR

Lambert-St Louis

Wed 22/4

21:35-11:35

Nonstop8h 00m

London Heathrow

Sun 3/5

16:25-19:30

Nonstop9h 05m

£526

St. LouisLondon

STL - LHR

STLLHR

Lambert-St Louis

Fri 24/4

21:35-11:35

Nonstop8h 00m

London Heathrow

Tue 5/5

16:25-19:30

Nonstop9h 05m

£526

St. LouisLondon

STL - LHR

STLLHR

Lambert-St Louis

Fri 24/4

21:35-11:35

Nonstop8h 00m

London Heathrow

Sun 3/5

16:25-19:30

Nonstop9h 05m

£564

St. LouisLondon

STL - LHR

STLLHR

Lambert-St Louis

Fri 24/4

21:35-11:35

Nonstop8h 00m

London Heathrow

Sun 26/4

16:25-19:30

Nonstop9h 05m

£564

St. LouisLondon

STL - LHR

STLLHR

Lambert-St Louis

Tue 21/4

21:35-11:35

Nonstop8h 00m

London Heathrow

Tue 12/5

16:25-19:30

Nonstop9h 05m

£610

St. LouisLondon

STL - LHR

STLLHR

Lambert-St Louis

Wed 6/5

21:35-11:35

Nonstop8h 00m

London Heathrow

Sun 10/5

16:25-19:30

Nonstop9h 05m

£624

Flights are sorted by cheapest return flights first.

Deals found on 18/1

Showing 1-10 of 18 results
1
2

Best time to book a flight from St. Louis

Have a flexible travel schedule? Discover the best time to fly from St. Louis with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines flying non-stop to St. Louis

Get insights into the airlines that provide direct flights from St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight from St. Louis. Reviews last updated Cheapflights.
Read through reviews of airlines serving St. Louis, such as Virgin Atlantic, Air Canada, andBritish Airways. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Virgin Atlantic
7.5
Good
678 reviews
Check prices

Overall

7.5

Food

6.9

Crew

8.2

Entertainment

7.6

Comfort

7.3

Boarding

7.7

Reviews

1 / 20
6.0
Good

Pratap,Aug 2025

JFK - LHR

The flight is clean, food good and the staff are excellent! Very professional, polite and accommodating. The seat itself is really mediocre. Can’t believe there is not inch of storage space. Believe it or not it there is not place even to put away your phone or pen!! Very very surprising and terribly inconvenient. No coat hanger hook either. Had to give it away. ALL IN ALL VERY INCONVENIENT business class seat compared to their peers. What is even more surprising is that this on their relatively new fleet of Airbus A350-1000. I was having com platelets different expectations of Virgin and this has disappointed me. Everything else is just as good and as you would expect from Virgin!
Virgin Atlantic
7.5
Good
678 reviews
Virgin Atlantic
7.5
Good
678 reviews
Check prices

Overall

7.5

Food

6.9

Crew

8.2

Entertainment

7.6

Comfort

7.3

Boarding

7.7

Reviews

1 / 20
6.0
Good

Pratap,Aug 2025

JFK - LHR

The flight is clean, food good and the staff are excellent! Very professional, polite and accommodating. The seat itself is really mediocre. Can’t believe there is not inch of storage space. Believe it or not it there is not place even to put away your phone or pen!! Very very surprising and terribly inconvenient. No coat hanger hook either. Had to give it away. ALL IN ALL VERY INCONVENIENT business class seat compared to their peers. What is even more surprising is that this on their relatively new fleet of Airbus A350-1000. I was having com platelets different expectations of Virgin and this has disappointed me. Everything else is just as good and as you would expect from Virgin!
Air Canada
7.1
Good
10,637 reviews
Virgin Atlantic
7.5
Good
678 reviews
Check prices

Overall

7.5

Food

6.9

Crew

8.2

Entertainment

7.6

Comfort

7.3

Boarding

7.7

Reviews

1 / 20
6.0
Good

Pratap,Aug 2025

JFK - LHR

The flight is clean, food good and the staff are excellent! Very professional, polite and accommodating. The seat itself is really mediocre. Can’t believe there is not inch of storage space. Believe it or not it there is not place even to put away your phone or pen!! Very very surprising and terribly inconvenient. No coat hanger hook either. Had to give it away. ALL IN ALL VERY INCONVENIENT business class seat compared to their peers. What is even more surprising is that this on their relatively new fleet of Airbus A350-1000. I was having com platelets different expectations of Virgin and this has disappointed me. Everything else is just as good and as you would expect from Virgin!
British Airways
6.7
Okay
7,690 reviews
Virgin Atlantic
7.5
Good
678 reviews
Check prices

Overall

7.5

Food

6.9

Crew

8.2

Entertainment

7.6

Comfort

7.3

Boarding

7.7

Reviews

1 / 20
6.0
Good

Pratap,Aug 2025

JFK - LHR

The flight is clean, food good and the staff are excellent! Very professional, polite and accommodating. The seat itself is really mediocre. Can’t believe there is not inch of storage space. Believe it or not it there is not place even to put away your phone or pen!! Very very surprising and terribly inconvenient. No coat hanger hook either. Had to give it away. ALL IN ALL VERY INCONVENIENT business class seat compared to their peers. What is even more surprising is that this on their relatively new fleet of Airbus A350-1000. I was having com platelets different expectations of Virgin and this has disappointed me. Everything else is just as good and as you would expect from Virgin!

Related info for your journey

Access useful and relevant information related to your journey from St. Louis. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 21 January 2026.

  • Where can you fly direct from St. Louis?

    Currently, the most popular direct flight destination from St. Louis is Salt Lake City.

  • What is the best time of year to fly direct from St. Louis?

    If you're seeking the lowest price on a direct flight from St. Louis, October is worth consideration as prices are at their lowest, on average. In terms of the number of daily non-stop flights, November offers travelers the most options.

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