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£350+ Direct flights from St. Louis

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 17/5. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
STL — LHR
27 Dec — 3 Jan1
1 adult
1 adult, Economy, 0 bags

Direct flights from St. Louis

Enter your travel dates to find the best prices.

Cheapest flights from St. Louis
Explore the most affordable flight options available from St. Louis. Find the lowest fares based on data from user searches, with prices last updated on 27 November 2025.

Fri 24/422:00STL - LHR
Nonstop8h 05mBritish Airways
Fri 1/516:25LHR - STL
Nonstop9h 05mBritish Airways
Deal found 23/11£528
Sun 10/522:00STL - LHR
Nonstop8h 05mIberia
Fri 22/516:25LHR - STL
Nonstop9h 05mIberia
Deal found 25/11£535
Sun 10/522:00STL - LHR
Nonstop8h 05mBritish Airways
Fri 22/516:25LHR - STL
Nonstop9h 05mBritish Airways
Deal found 24/11£561
Tue 12/522:00STL - LHR
Nonstop8h 05mBritish Airways
Sun 17/516:25LHR - STL
Nonstop9h 05mBritish Airways
Deal found 23/11£570
Tue 19/522:00STL - LHR
Nonstop8h 05mBritish Airways
Tue 26/516:25LHR - STL
Nonstop9h 05mBritish Airways
Deal found 25/11£614
Tue 19/522:00STL - LHR
Nonstop8h 05mBritish Airways
Fri 22/516:25LHR - STL
Nonstop9h 05mBritish Airways
Deal found 25/11£645
Tue 19/522:00STL - LHR
Nonstop8h 05mAmerican Airlines
Tue 26/516:25LHR - STL
Nonstop9h 05mAmerican Airlines
Deal found 25/11£671
Tue 19/522:00STL - LHR
Nonstop8h 05mAmerican Airlines
Tue 28/716:25LHR - STL
Nonstop9h 05mAmerican Airlines
Deal found 25/11£800
Fri 22/522:00STL - LHR
Nonstop8h 05mBritish Airways
Fri 5/616:25LHR - STL
Nonstop9h 05mBritish Airways
Deal found 23/11£1,220

Find direct flights from St. Louis within your budget

 
Use the slider to find direct flights from St. Louis within your budget. Price data is based on user searches made on Cheapflights. Over the past seven days, Cheapflights users made 858,174 searches. This data was last updated on 27 November 2025.

Fly to

Heathrow

Route

Depart

Return

Price

St. LouisLondon

STL - LHR

STLLHR

Lambert-St Louis

Fri 1/5

22:00-12:05

Nonstop8h 05m

London Heathrow

Fri 8/5

16:25-19:30

Nonstop9h 05m

£544

St. LouisLondon

STL - LHR

STLLHR

Lambert-St Louis

Tue 12/5

22:00-12:05

Nonstop8h 05m

London Heathrow

Sun 17/5

16:25-19:30

Nonstop9h 05m

£572

St. LouisLondon

STL - LHR

STLLHR

Lambert-St Louis

Tue 19/5

22:00-12:05

Nonstop8h 05m

London Heathrow

Tue 26/5

16:25-19:30

Nonstop9h 05m

£614

St. LouisLondon

STL - LHR

STLLHR

Lambert-St Louis

Tue 19/5

22:00-12:05

Nonstop8h 05m

London Heathrow

Fri 22/5

16:25-19:30

Nonstop9h 05m

£645

St. LouisLondon

STL - LHR

STLLHR

Lambert-St Louis

Tue 19/5

22:00-12:05

Nonstop8h 05m

London Heathrow

Tue 26/5

16:25-19:30

Nonstop9h 05m

£671

St. LouisLondon

STL - LHR

STLLHR

Lambert-St Louis

Tue 19/5

22:00-12:05

Nonstop8h 05m

London Heathrow

Tue 28/7

16:25-19:30

Nonstop9h 05m

£800

St. LouisLondon

STL - LHR

STLLHR

Lambert-St Louis

Tue 26/5

22:00-12:05

Nonstop8h 05m

London Heathrow

Fri 5/6

16:25-19:30

Nonstop9h 05m

£811

St. LouisLondon

STL - LHR

STLLHR

Lambert-St Louis

Tue 26/5

22:00-12:05

Nonstop8h 05m

London Heathrow

Sun 7/6

16:25-19:30

Nonstop9h 05m

£857

St. LouisLondon

STL - LHR

STLLHR

Lambert-St Louis

Tue 26/5

22:00-12:05

Nonstop8h 05m

London Heathrow

Tue 9/6

16:25-19:30

Nonstop9h 05m

£923

St. LouisLondon

STL - LHR

STLLHR

Lambert-St Louis

Tue 12/5

22:00-12:05

Nonstop8h 05m

London Heathrow

Tue 19/5

16:25-19:30

Nonstop9h 05m

£3,708

Flights are sorted by cheapest return flights first.

Deals found on 26/11

Showing 1-10 of 13 results
1
2

Best time to book a flight from St. Louis

Have a flexible travel schedule? Discover the best time to fly from St. Louis with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines flying non-stop to St. Louis

Get insights into the airlines that provide direct flights from St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight from St. Louis. Reviews last updated Cheapflights.
Read through reviews of airlines serving St. Louis, such as KLM, Virgin Atlantic, andAir Canada. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7.7
Good
1,423 reviews
Check prices

Crew

8.4

Comfort

7.6

Boarding

7.8

Overall

7.7

Food

7.2

Entertainment

7.1

Reviews

1 / 20
2.0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.
KLM
7.7
Good
1,423 reviews
KLM
7.7
Good
1,423 reviews
Check prices

Crew

8.4

Comfort

7.6

Boarding

7.8

Overall

7.7

Food

7.2

Entertainment

7.1

Reviews

1 / 20
2.0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.
Virgin Atlantic
7.5
Good
675 reviews
KLM
7.7
Good
1,423 reviews
Check prices

Crew

8.4

Comfort

7.6

Boarding

7.8

Overall

7.7

Food

7.2

Entertainment

7.1

Reviews

1 / 20
2.0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.
Air Canada
7.1
Good
10,481 reviews
KLM
7.7
Good
1,423 reviews
Check prices

Crew

8.4

Comfort

7.6

Boarding

7.8

Overall

7.7

Food

7.2

Entertainment

7.1

Reviews

1 / 20
2.0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.
British Airways
6.7
Okay
7,539 reviews
KLM
7.7
Good
1,423 reviews
Check prices

Crew

8.4

Comfort

7.6

Boarding

7.8

Overall

7.7

Food

7.2

Entertainment

7.1

Reviews

1 / 20
2.0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.

Related info for your journey

Access useful and relevant information related to your journey from St. Louis. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 27 November 2025.

  • Where can you fly direct from St. Louis?

    Currently, the most popular direct flight destination from St. Louis is Tampa.

  • How much are direct flights from St. Louis?

    On average, a one-way direct flight from St. Louis will cost users approximately £322. If you're looking for a direct round-trip flight from St. Louis, you can expect to pay around £491.

  • How long is a direct flight from St. Louis?

    While the flight duration depends heavily on the destination, on average, travelers can expect non-stop flights from St. Louis to last approximately 6h 05m on average. The quickest direct flight from St. Louis at this time departs from St. Louis (4h 05m), while the longest leaves from St. Louis (8h 05m).

  • What is the best time of year to fly direct from St. Louis?

    If you're seeking the lowest price on a direct flight from St. Louis, October is worth consideration as prices are at their lowest, on average. In terms of the number of daily non-stop flights, February offers travelers the most options.

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