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£273+ Direct flights from St. Louis

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/5. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
STL — LHR
7 Feb — 14 Feb1
1 adult
1 adult, Economy, 0 bags

Direct flights from St. Louis

Enter your travel dates to find the best prices.

Cheapest flights from St. Louis
Explore the most affordable flight options available from St. Louis. Find the lowest fares based on data from user searches, with prices last updated on 8 January 2026.

Fri 24/421:35STL - LHR
Nonstop8h 00mBritish Airways
Sun 3/516:25LHR - STL
Nonstop9h 05mBritish Airways
Deal found 7/1£516
Tue 12/522:00STL - LHR
Nonstop8h 05mBritish Airways
Wed 20/516:25LHR - STL
Nonstop9h 05mBritish Airways
Deal found 7/1£522
Sun 10/521:40STL - LHR
Nonstop8h 00mBritish Airways
Fri 22/516:25LHR - STL
Nonstop9h 05mBritish Airways
Deal found 7/1£528
Fri 1/521:35STL - LHR
Nonstop8h 00mAmerican Airlines
Fri 15/516:25LHR - STL
Nonstop9h 05mAmerican Airlines
Deal found 7/1£532
Wed 29/422:00STL - LHR
Nonstop8h 05mBritish Airways
Sun 3/516:25LHR - STL
Nonstop9h 05mBritish Airways
Deal found 6/1£537
Sun 10/522:00STL - LHR
Nonstop8h 05mFinnair
Sun 17/516:25LHR - STL
Nonstop9h 05mFinnair
Deal found 6/1£551
Sun 19/421:40STL - LHR
Nonstop8h 00mBritish Airways
Sun 26/416:25LHR - STL
Nonstop9h 05mBritish Airways
Deal found 7/1£564
Wed 13/522:00STL - LHR
Nonstop8h 05mBritish Airways
Tue 2/616:25LHR - STL
Nonstop9h 05mBritish Airways
Deal found 6/1£571
Wed 13/521:35STL - LHR
Nonstop8h 00mBritish Airways
Fri 22/516:25LHR - STL
Nonstop9h 05mBritish Airways
Deal found 7/1£596
Sun 17/521:40STL - LHR
Nonstop8h 00mBritish Airways
Wed 27/516:25LHR - STL
Nonstop9h 05mBritish Airways
Deal found 7/1£609
Wed 13/522:00STL - LHR
Nonstop8h 05mBritish Airways
Sun 24/516:25LHR - STL
Nonstop9h 05mBritish Airways
Deal found 6/1£615
Wed 13/521:35STL - LHR
Nonstop8h 00mAmerican Airlines
Sun 24/516:25LHR - STL
Nonstop9h 05mAmerican Airlines
Deal found 6/1£628

Find direct flights from St. Louis within your budget

 
Use the slider to find direct flights from St. Louis within your budget. Price data is based on user searches made on Cheapflights. Over the past seven days, Cheapflights users made 858,174 searches. This data was last updated on 8 January 2026.

Fly to

Heathrow

Route

Depart

Return

Price

St. LouisLondon

STL - LHR

STLLHR

Lambert-St Louis

Fri 24/4

21:35-11:35

Nonstop8h 00m

London Heathrow

Sun 3/5

16:25-19:30

Nonstop9h 05m

£516

St. LouisLondon

STL - LHR

STLLHR

Lambert-St Louis

Tue 12/5

22:00-12:05

Nonstop8h 05m

London Heathrow

Wed 20/5

16:25-19:30

Nonstop9h 05m

£522

St. LouisLondon

STL - LHR

STLLHR

Lambert-St Louis

Fri 1/5

21:35-11:35

Nonstop8h 00m

London Heathrow

Fri 8/5

16:25-19:30

Nonstop9h 05m

£525

St. LouisLondon

STL - LHR

STLLHR

Lambert-St Louis

Wed 6/5

21:35-11:35

Nonstop8h 00m

London Heathrow

Sun 10/5

16:25-19:30

Nonstop9h 05m

£525

St. LouisLondon

STL - LHR

STLLHR

Lambert-St Louis

Sun 3/5

21:40-11:40

Nonstop8h 00m

London Heathrow

Sun 10/5

16:25-19:30

Nonstop9h 05m

£525

St. LouisLondon

STL - LHR

STLLHR

Lambert-St Louis

Sun 10/5

22:00-12:05

Nonstop8h 05m

London Heathrow

Fri 22/5

16:25-19:30

Nonstop9h 05m

£528

St. LouisLondon

STL - LHR

STLLHR

Lambert-St Louis

Sun 10/5

22:00-12:05

Nonstop8h 05m

London Heathrow

Sun 17/5

16:25-19:30

Nonstop9h 05m

£551

St. LouisLondon

STL - LHR

STLLHR

Lambert-St Louis

Tue 12/5

22:00-12:05

Nonstop8h 05m

London Heathrow

Sun 17/5

16:25-19:30

Nonstop9h 05m

£564

St. LouisLondon

STL - LHR

STLLHR

Lambert-St Louis

Sun 17/5

22:00-12:05

Nonstop8h 05m

London Heathrow

Wed 27/5

16:25-19:30

Nonstop9h 05m

£609

St. LouisLondon

STL - LHR

STLLHR

Lambert-St Louis

Wed 13/5

21:35-11:35

Nonstop8h 00m

London Heathrow

Sun 24/5

16:25-19:30

Nonstop9h 05m

£628

Flights are sorted by cheapest return flights first.

Deals found on 7/1

Showing 1-10 of 20 results
1
2

Best time to book a flight from St. Louis

Have a flexible travel schedule? Discover the best time to fly from St. Louis with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines flying non-stop to St. Louis

Get insights into the airlines that provide direct flights from St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight from St. Louis. Reviews last updated Cheapflights.
Read through reviews of airlines serving St. Louis, such as Virgin Atlantic, Air Canada, andBritish Airways. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Virgin Atlantic
7.5
Good
678 reviews
Check prices

Food

6.9

Overall

7.5

Crew

8.2

Comfort

7.3

Entertainment

7.6

Boarding

7.7

Reviews

1 / 20
6.0
Good

Pratap,Aug 2025

JFK - LHR

The flight is clean, food good and the staff are excellent! Very professional, polite and accommodating. The seat itself is really mediocre. Can’t believe there is not inch of storage space. Believe it or not it there is not place even to put away your phone or pen!! Very very surprising and terribly inconvenient. No coat hanger hook either. Had to give it away. ALL IN ALL VERY INCONVENIENT business class seat compared to their peers. What is even more surprising is that this on their relatively new fleet of Airbus A350-1000. I was having com platelets different expectations of Virgin and this has disappointed me. Everything else is just as good and as you would expect from Virgin!
Virgin Atlantic
7.5
Good
678 reviews
Virgin Atlantic
7.5
Good
678 reviews
Check prices

Food

6.9

Overall

7.5

Crew

8.2

Comfort

7.3

Entertainment

7.6

Boarding

7.7

Reviews

1 / 20
6.0
Good

Pratap,Aug 2025

JFK - LHR

The flight is clean, food good and the staff are excellent! Very professional, polite and accommodating. The seat itself is really mediocre. Can’t believe there is not inch of storage space. Believe it or not it there is not place even to put away your phone or pen!! Very very surprising and terribly inconvenient. No coat hanger hook either. Had to give it away. ALL IN ALL VERY INCONVENIENT business class seat compared to their peers. What is even more surprising is that this on their relatively new fleet of Airbus A350-1000. I was having com platelets different expectations of Virgin and this has disappointed me. Everything else is just as good and as you would expect from Virgin!
Air Canada
7.1
Good
10,603 reviews
Virgin Atlantic
7.5
Good
678 reviews
Check prices

Food

6.9

Overall

7.5

Crew

8.2

Comfort

7.3

Entertainment

7.6

Boarding

7.7

Reviews

1 / 20
6.0
Good

Pratap,Aug 2025

JFK - LHR

The flight is clean, food good and the staff are excellent! Very professional, polite and accommodating. The seat itself is really mediocre. Can’t believe there is not inch of storage space. Believe it or not it there is not place even to put away your phone or pen!! Very very surprising and terribly inconvenient. No coat hanger hook either. Had to give it away. ALL IN ALL VERY INCONVENIENT business class seat compared to their peers. What is even more surprising is that this on their relatively new fleet of Airbus A350-1000. I was having com platelets different expectations of Virgin and this has disappointed me. Everything else is just as good and as you would expect from Virgin!
British Airways
6.7
Okay
7,657 reviews
Virgin Atlantic
7.5
Good
678 reviews
Check prices

Food

6.9

Overall

7.5

Crew

8.2

Comfort

7.3

Entertainment

7.6

Boarding

7.7

Reviews

1 / 20
6.0
Good

Pratap,Aug 2025

JFK - LHR

The flight is clean, food good and the staff are excellent! Very professional, polite and accommodating. The seat itself is really mediocre. Can’t believe there is not inch of storage space. Believe it or not it there is not place even to put away your phone or pen!! Very very surprising and terribly inconvenient. No coat hanger hook either. Had to give it away. ALL IN ALL VERY INCONVENIENT business class seat compared to their peers. What is even more surprising is that this on their relatively new fleet of Airbus A350-1000. I was having com platelets different expectations of Virgin and this has disappointed me. Everything else is just as good and as you would expect from Virgin!

Related info for your journey

Access useful and relevant information related to your journey from St. Louis. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 8 January 2026.

  • Where can you fly direct from St. Louis?

    Currently, the most popular direct flight destination from St. Louis is Tampa.

  • What is the best time of year to fly direct from St. Louis?

    If you're seeking the lowest price on a direct flight from St. Louis, October is worth consideration as prices are at their lowest, on average. In terms of the number of daily non-stop flights, September offers travelers the most options.

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