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£103+ Direct flights from St. Louis

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 18/12. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
STL — LHR
18 Oct — 25 Oct1
1 adult
1 adult, Economy

Direct flights from St. Louis

Cheapest flights from St. Louis
Explore the most affordable flight options available from St. Louis. Find the lowest fares based on data from user searches, with prices last updated on 18 September 2025.

Tue 14/1005:40STL - LAS
Nonstop3h 35mSouthwest
Sat 1/1115:55LAS - STL
Nonstop3h 15mSouthwest
Deal found 16/9£276
Fri 24/1020:10STL - LAS
Nonstop3h 30mSouthwest
Tue 28/1012:45LAS - STL
Nonstop3h 10mSouthwest
Deal found 17/9£295
Sun 19/1019:50STL - LAS
Nonstop3h 30mSouthwest
Wed 22/1005:50LAS - STL
Nonstop3h 10mSouthwest
Deal found 17/9£296
Mon 6/1020:10STL - LAS
Nonstop3h 30mSouthwest
Tue 7/1017:55LAS - STL
Nonstop3h 15mSouthwest
Deal found 15/9£303
Wed 19/1105:00STL - LAS
Nonstop3h 45mSouthwest
Wed 26/1107:15LAS - STL
Nonstop3h 05mSouthwest
Deal found 16/9£305
Thu 23/1005:10STL - LAS
Nonstop3h 30mSouthwest
Sun 26/1020:25LAS - STL
Nonstop3h 15mSouthwest
Deal found 16/9£316
Wed 15/1005:40STL - LAS
Nonstop3h 35mSouthwest
Sun 19/1020:25LAS - STL
Nonstop3h 15mSouthwest
Deal found 17/9£336
Mon 16/219:55STL - LAS
Nonstop3h 45mSouthwest
Thu 19/208:45LAS - STL
Nonstop3h 10mSouthwest
Deal found 16/9£337
Sun 12/1005:15STL - LAS
Nonstop3h 30mSouthwest
Sun 19/1020:25LAS - STL
Nonstop3h 15mSouthwest
Deal found 17/9£344
Tue 16/1207:35STL - LAS
Nonstop3h 40mSouthwest
Fri 19/1213:05LAS - STL
Nonstop3h 10mSouthwest
Deal found 17/9£352
Sat 14/217:35STL - LAS
Nonstop3h 45mSouthwest
Tue 17/213:55LAS - STL
Nonstop3h 10mSouthwest
Deal found 16/9£357
Thu 2/1005:10STL - LAS
Nonstop3h 30mSouthwest
Tue 7/1017:55LAS - STL
Nonstop3h 15mSouthwest
Deal found 16/9£366

Find direct flights from St. Louis within your budget

 
Use the slider to find direct flights from St. Louis within your budget. Price data is based on user searches made on Cheapflights. Over the past seven days, Cheapflights users made 858,174 searches. This data was last updated on 18 September 2025.

Fly to

Heathrow

Route

Depart

Return

Price

St. LouisLas Vegas

STL - LAS

STLLAS

Lambert-St Louis

Mon 23/2

20:50-22:35

Nonstop3h 45m

Las Vegas Harry Reid Intl

Thu 26/2

18:05-23:15

Nonstop3h 10m

£276

St. LouisLas Vegas

STL - LAS

STLLAS

Lambert-St Louis

Tue 2/12

13:05-14:40

Nonstop3h 35m

Las Vegas Harry Reid Intl

Sat 6/12

17:20-22:25

Nonstop3h 05m

£276

St. LouisLas Vegas

STL - LAS

STLLAS

Lambert-St Louis

Tue 14/10

05:40-07:15

Nonstop3h 35m

Las Vegas Harry Reid Intl

Tue 21/10

05:50-11:00

Nonstop3h 10m

£276

St. LouisLas Vegas

STL - LAS

STLLAS

Lambert-St Louis

Tue 4/11

05:00-06:45

Nonstop3h 45m

Las Vegas Harry Reid Intl

Sat 8/11

17:20-22:25

Nonstop3h 05m

£276

St. LouisLas Vegas

STL - LAS

STLLAS

Lambert-St Louis

Wed 15/10

05:40-07:15

Nonstop3h 35m

Las Vegas Harry Reid Intl

Wed 22/10

16:45-21:55

Nonstop3h 10m

£276

St. LouisLas Vegas

STL - LAS

STLLAS

Lambert-St Louis

Wed 3/12

20:25-22:00

Nonstop3h 35m

Las Vegas Harry Reid Intl

Sat 6/12

06:15-11:25

Nonstop3h 10m

£276

St. LouisLas Vegas

STL - LAS

STLLAS

Lambert-St Louis

Thu 30/10

05:10-06:40

Nonstop3h 30m

Las Vegas Harry Reid Intl

Tue 4/11

16:30-21:35

Nonstop3h 05m

£276

St. LouisLas Vegas

STL - LAS

STLLAS

Lambert-St Louis

Thu 20/11

05:00-06:45

Nonstop3h 45m

Las Vegas Harry Reid Intl

Sat 22/11

20:40-01:45

Nonstop3h 05m

£276

St. LouisLas Vegas

STL - LAS

STLLAS

Lambert-St Louis

Sat 1/11

18:05-19:40

Nonstop3h 35m

Las Vegas Harry Reid Intl

Tue 4/11

18:00-23:10

Nonstop3h 10m

£276

St. LouisLas Vegas

STL - LAS

STLLAS

Lambert-St Louis

Wed 22/10

15:00-16:30

Nonstop3h 30m

Las Vegas Harry Reid Intl

Thu 23/10

17:45-23:00

Nonstop3h 15m

£276

Flights are sorted by cheapest return flights first.

Deals found on 18/9

Showing 1-10 of 21 results
1
2
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Best time to book a flight from St. Louis

Have a flexible travel schedule? Discover the best time to fly from St. Louis with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines flying non-stop to St. Louis

Get insights into the airlines that provide direct flights from St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight from St. Louis. Reviews last updated Cheapflights.
Read through reviews of airlines serving St. Louis, such as KLM, Virgin Atlantic, andAir Canada. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7.8
Good
1,386 reviews
Check prices

Entertainment

7.2

Food

7.3

Overall

7.8

Comfort

7.7

Crew

8.4

Boarding

7.8

Reviews

1 / 20
4.0
Okay

Mark,Sept 2025

AMS - BHX

Crew and snacks were good, boarding wasn't great as busses were used rather than boarding tunnels. Also endured a one hour delay.
KLM
7.8
Good
1,386 reviews
KLM
7.8
Good
1,386 reviews
Check prices

Entertainment

7.2

Food

7.3

Overall

7.8

Comfort

7.7

Crew

8.4

Boarding

7.8

Reviews

1 / 20
4.0
Okay

Mark,Sept 2025

AMS - BHX

Crew and snacks were good, boarding wasn't great as busses were used rather than boarding tunnels. Also endured a one hour delay.
Virgin Atlantic
7.4
Good
664 reviews
KLM
7.8
Good
1,386 reviews
Check prices

Entertainment

7.2

Food

7.3

Overall

7.8

Comfort

7.7

Crew

8.4

Boarding

7.8

Reviews

1 / 20
4.0
Okay

Mark,Sept 2025

AMS - BHX

Crew and snacks were good, boarding wasn't great as busses were used rather than boarding tunnels. Also endured a one hour delay.
Air Canada
7.1
Good
10,000 reviews
KLM
7.8
Good
1,386 reviews
Check prices

Entertainment

7.2

Food

7.3

Overall

7.8

Comfort

7.7

Crew

8.4

Boarding

7.8

Reviews

1 / 20
4.0
Okay

Mark,Sept 2025

AMS - BHX

Crew and snacks were good, boarding wasn't great as busses were used rather than boarding tunnels. Also endured a one hour delay.
British Airways
6.7
Okay
7,367 reviews
KLM
7.8
Good
1,386 reviews
Check prices

Entertainment

7.2

Food

7.3

Overall

7.8

Comfort

7.7

Crew

8.4

Boarding

7.8

Reviews

1 / 20
4.0
Okay

Mark,Sept 2025

AMS - BHX

Crew and snacks were good, boarding wasn't great as busses were used rather than boarding tunnels. Also endured a one hour delay.

Related info for your journey

Access useful and relevant information related to your journey from St. Louis. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 18 September 2025.

  • Where can you fly direct from St. Louis?

    Currently, the most popular direct flight destination from St. Louis is Chicago O'Hare Intl Airport.

  • How much are direct flights from St. Louis?

    On average, a one-way direct flight from St. Louis will cost users approximately £163. If you're looking for a direct round-trip flight from St. Louis, you can expect to pay around £689.

  • How long is a direct flight from St. Louis?

    While the flight duration depends heavily on the destination, on average, travelers can expect non-stop flights from St. Louis to last approximately 3h 37m on average. The quickest direct flight from St. Louis at this time departs from St. Louis (2h 39m), while the longest leaves from St. Louis (4h 35m).

  • What is the best time of year to fly direct from St. Louis?

    If you're seeking the lowest price on a direct flight from St. Louis, August is worth consideration as prices are at their lowest, on average. In terms of the number of daily non-stop flights, August offers travelers the most options.

See more FAQs

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