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£85+ Cheap flights from Panama

This is the cheapest return flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/1. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
PTY — LHR
27 Dec — 3 Jan1
1 adult
1 adult, Economy, 0 bags

What to know about flights from Panama

Discover essential information about flights departing from Panama, including flight schedules, destinations, airlines operating at the Panama airport, and any specific guidelines or requirements for travellers. Please note that the information is based on the most recent updates available. Data last updated 27 November 2025.

Good round-trip deal

£201 or less

Good one-way deal

£68 or less
Price to beat on a round-trip flight from Panama.
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Price to beat on a one-way flight from Panama.
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Find flights from Panama

Enter your travel dates to find the best prices.

Cheapest flights from Panama
Explore the most affordable flight options available from Panama. Find the lowest fares based on data from user searches, with prices last updated on 27 November 2025.

Sat 13/1211:34PTY - SAP
Nonstop2h 14mCopa Airlines
Sat 20/1204:26SAP - PTY
Nonstop2h 13mCopa Airlines
Deal found 25/11£221
Thu 15/111:34PTY - SAP
Nonstop2h 06mCopa Airlines
Thu 22/113:52SAP - PTY
Nonstop2h 09mCopa Airlines
Deal found 25/11£237
Tue 17/322:19PTY - SAP
Nonstop2h 10mCopa Airlines
Tue 24/313:50SAP - PTY
Nonstop2h 13mCopa Airlines
Deal found 24/11£254
Wed 31/1211:34PTY - SAP
Nonstop2h 14mCopa Airlines
Thu 1/113:52SAP - PTY
Nonstop2h 09mCopa Airlines
Deal found 26/11£260
Sat 13/1219:50PTY - SAP
1 stop13h 40mMultiple Airlines
Sun 21/1213:53SAP - PTY
Nonstop2h 08mMultiple Airlines
Deal found 25/11£295
Sat 13/1219:50PTY - SAP
1 stop13h 40mAvianca
Sun 21/1209:25SAP - PTY
1 stop8h 30mAvianca
Deal found 25/11£316
Mon 6/422:15PTY - BRU
1 stop28h 55mTurkish Airlines
Wed 27/507:20BRU - PTY
1 stop20h 00mTurkish Airlines
Deal found 25/11£594
Sun 5/420:10PTY - BRU
1 stop34h 15mTurkish Airlines
Tue 26/511:10BRU - PTY
1 stop40h 10mTurkish Airlines
Deal found 25/11£602
Sat 14/222:05PTY - BRU
1 stop18h 15mKLM
Thu 26/208:05BRU - PTY
1 stop14h 25mKLM
Deal found 25/11£603
Mon 6/422:15PTY - BRU
1 stop36h 35mTurkish Airlines
Fri 29/511:10BRU - PTY
1 stop40h 10mTurkish Airlines
Deal found 25/11£617
Wed 8/422:15PTY - BRU
1 stop32h 10mTurkish Airlines
Sun 31/516:15BRU - PTY
1 stop35h 05mTurkish Airlines
Deal found 25/11£618
Sun 5/420:10PTY - BRU
1 stop31h 00mTurkish Airlines
Sun 31/514:25BRU - PTY
1 stop36h 55mTurkish Airlines
Deal found 25/11£625

Find flights from Panama within your budget

 
Find flights departing from Panama that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 27 November 2025. In the last 7 days, Cheapflights users made a total of 858,174 searches

Fly to

Heathrow

Route

Depart

Return

Price

Panama CitySan Pedro Sula

PTY - SAP

PTYSAP

Panama City Tocumen Intl

Sat 13/12

22:19-23:33

Nonstop2h 14m

San Pedro Sula Ramon Villeda

Sun 21/12

13:53-17:01

Nonstop2h 08m

£221

Panama CitySan Pedro Sula

PTY - SAP

PTYSAP

Panama City Tocumen Intl

Sat 13/12

11:34-12:48

Nonstop2h 14m

San Pedro Sula Ramon Villeda

Thu 8/1

04:25-07:39

Nonstop2h 14m

£221

Panama CitySan Pedro Sula

PTY - SAP

PTYSAP

Panama City Tocumen Intl

Thu 25/12

11:34-12:48

Nonstop2h 14m

San Pedro Sula Ramon Villeda

Thu 1/1

13:52-17:01

Nonstop2h 09m

£221

Panama CitySan Pedro Sula

PTY - SAP

PTYSAP

Panama City Tocumen Intl

Fri 26/12

22:19-23:33

Nonstop2h 14m

San Pedro Sula Ramon Villeda

Fri 2/1

13:52-17:01

Nonstop2h 09m

£221

Panama CitySan Pedro Sula

PTY - SAP

PTYSAP

Panama City Tocumen Intl

Tue 16/12

11:34-12:48

Nonstop2h 14m

San Pedro Sula Ramon Villeda

Wed 17/12

13:53-17:01

Nonstop2h 08m

£221

Panama CitySan Pedro Sula

PTY - SAP

PTYSAP

Panama City Tocumen Intl

Tue 16/12

22:19-23:33

Nonstop2h 14m

San Pedro Sula Ramon Villeda

Sun 28/12

13:53-17:01

Nonstop2h 08m

£221

Panama CitySan Pedro Sula

PTY - SAP

PTYSAP

Panama City Tocumen Intl

Thu 15/1

11:34-12:40

Nonstop2h 06m

San Pedro Sula Ramon Villeda

Thu 22/1

13:52-17:01

Nonstop2h 09m

£237

Panama CitySan Pedro Sula

PTY - SAP

PTYSAP

Panama City Tocumen Intl

Tue 17/3

22:19-23:29

Nonstop2h 10m

San Pedro Sula Ramon Villeda

Tue 24/3

13:50-17:03

Nonstop2h 13m

£254

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Mon 6/4

22:15-10:10

1 stop28h 55m

Brussels Bruxelles-National

Wed 27/5

07:20-20:20

1 stop20h 00m

£594

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Sat 11/4

22:15-17:50

1 stop36h 35m

Brussels Bruxelles-National

Tue 26/5

11:10-20:20

1 stop40h 10m

£594

Flights are sorted by cheapest return flights first.

Deals found on 25/11

Showing 1-10 of 60 results
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Best time to book a flight from Panama

Have a flexible travel schedule? Discover the best time to fly from Panama with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama

Get recent, data-driven insights about flights from Panama including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Panama?

Currently, December is the cheapest month in which you can book a flight from Panama (average of £489). Flying from Panama in August will prove the most costly (average of £782). There are multiple factors that influence the price of a flight so comparing airlines, departure airports and times can help keep costs down.

Which airlines fly from Panama?

Many airlines operate round-trip flights from Panama: KLM, Air France, United Airlines. These airlines fly to the following popular destinations: London.

Copa Airlines
Copa Airlines
From £125
Air Panama
Air Panama
From £116
Wingo
Wingo
From £75
Avianca
Avianca
From £124

What is the cheapest place to fly to from Panama?

The cheapest city to fly to from Panama is Medellín Jose Maria Cordova Intl, with prices starting at £57. Explore other affordable destinations below.

Medellín Jose Maria Cordova Intl
Medellín Jose Maria Cordova Intl
From £57
Cartagena Rafael Nunez
Cartagena Rafael Nunez
From £68
San José Juan Santamaria Intl
San José Juan Santamaria Intl
From £89
Bocas Del Toro
Bocas Del Toro
From £104

Airline reviews for flights from Panama

Get insights into the airlines that provide service from Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing airline for your flight from Panama. In the last 7 days, Cheapflights users made a total of 858,174 searches.
Read through reviews of airlines serving Panama, such as KLM, Air France, andUnited Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7.7
Good
1,423 reviews
Check prices

Food

7.2

Crew

8.4

Overall

7.7

Boarding

7.8

Entertainment

7.1

Comfort

7.6

Reviews

1 / 20
2.0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.
KLM
7.7
Good
1,423 reviews
KLM
7.7
Good
1,423 reviews
Check prices

Food

7.2

Crew

8.4

Overall

7.7

Boarding

7.8

Entertainment

7.1

Comfort

7.6

Reviews

1 / 20
2.0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.
Air France
7.4
Good
1,498 reviews
KLM
7.7
Good
1,423 reviews
Check prices

Food

7.2

Crew

8.4

Overall

7.7

Boarding

7.8

Entertainment

7.1

Comfort

7.6

Reviews

1 / 20
2.0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.
United Airlines
7.4
Good
9,050 reviews
KLM
7.7
Good
1,423 reviews
Check prices

Food

7.2

Crew

8.4

Overall

7.7

Boarding

7.8

Entertainment

7.1

Comfort

7.6

Reviews

1 / 20
2.0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.

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Direct flights from Central America

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Direct flights from Panama City

Related info for your journey

Access useful and relevant information related to your journey from Panama. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 27 November 2025.

  • What is the cheapest month to fly from Panama?

    At the present moment the cheapest month to fly from Panama is currently December; with August being the most expensive. Prices will vary depending on multiple factors such as booking in advance, airline and departure airports and times.

  • Where are the cheapest places to fly to from Panama?

    Check out the cheapest flights from Panama to embark to:
    Travel from Panama City to San Pedro Sula from £216 round trip
    Travel from Panama City to London from £590 round trip

  • How does Cheapflights help users find flights from Panama?

    Cheapflights goes through 900+ travel sites to look for the best flight deals for flights from Panama. Too many options? Cheapflights also provides filters for things like airlines, price ranges, and number of stops to help you make a decision easily.

  • Why should you use Cheapflights to find cheap flight tickets from Panama?

    By finding flights from multiple airlines and providers at completely no cost, Cheapflights helps millions of users like you annually find the best flights from Panama.

  • Can Cheapflights find flights from Panama with no change fees?

    Certainly. Search results for flights from Panama shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

  • Can Cheapflights notify me if prices for flights from Panama become cheaper?

    Not ready to book yet? You can track prices for flights from Panama on Cheapflights with our Price Alerts feature and get notified when better prices are available.

See more FAQs

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Panama?

Cheapflights goes through 900+ travel sites to look for the best flight deals for flights from Panama. Too many options? Cheapflights also provides filters for things like airlines, price ranges, and number of stops to help you make a decision easily.

Why should you use Cheapflights to find cheap flight tickets from Panama?

By finding flights from multiple airlines and providers at completely no cost, Cheapflights helps millions of users like you annually find the best flights from Panama.

Can Cheapflights find flights from Panama with no change fees?

Certainly. Search results for flights from Panama shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Panama become cheaper?

Not ready to book yet? You can track prices for flights from Panama on Cheapflights with our Price Alerts feature and get notified when better prices are available.

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