£72+ Cheap flights from Panama
This is the cheapest return flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 21/11. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
What to know about flights from Panama
Discover essential information about flights departing from Panama, including flight schedules, destinations, airlines operating at the Panama airport, and any specific guidelines or requirements for travellers. Please note that the information is based on the most recent updates available. Data last updated 10 October 2025.
Good round-trip deal | £121 or less |
---|---|
Good one-way deal | £68 or less |
Find flights from Panama
Cheapest flights from PanamaExplore the most affordable flight options available from Panama. Find the lowest fares based on data from user searches, with prices last updated on 10 October 2025.
Explore the most affordable flight options available from Panama. Find the lowest fares based on data from user searches, with prices last updated on 10 October 2025.
Find flights from Panama within your budget
Fly to
Route
Depart
Return
Price
Panama CitySan Pedro Sula
PTY - SAP
PTYSAP
Panama City Tocumen Intl
Wed 5/11
11:34-12:48
Nonstop2h 14m
San Pedro Sula Ramon Villeda
Wed 12/11
13:53-17:01
Nonstop2h 08m
Panama CitySan Pedro Sula
PTY - SAP
PTYSAP
Panama City Tocumen Intl
Sat 1/11
11:34-12:48
Nonstop2h 14m
San Pedro Sula Ramon Villeda
Wed 5/11
13:53-17:01
Nonstop2h 08m
Panama CitySan Pedro Sula
PTY - SAP
PTYSAP
Panama City Tocumen Intl
Thu 30/10
11:34-12:45
Nonstop2h 11m
San Pedro Sula Ramon Villeda
Wed 5/11
13:53-17:01
Nonstop2h 08m
Panama CitySan Pedro Sula
PTY - SAP
PTYSAP
Panama City Tocumen Intl
Tue 4/11
11:34-12:48
Nonstop2h 14m
San Pedro Sula Ramon Villeda
Sat 8/11
13:53-17:01
Nonstop2h 08m
Panama CitySan Pedro Sula
PTY - SAP
PTYSAP
Panama City Tocumen Intl
Fri 31/10
11:34-12:45
Nonstop2h 11m
San Pedro Sula Ramon Villeda
Wed 5/11
13:53-17:01
Nonstop2h 08m
Panama CitySan Pedro Sula
PTY - SAP
PTYSAP
Panama City Tocumen Intl
Sat 1/11
11:34-12:48
Nonstop2h 14m
San Pedro Sula Ramon Villeda
Mon 10/11
13:53-17:01
Nonstop2h 08m
Panama CitySan Pedro Sula
PTY - SAP
PTYSAP
Panama City Tocumen Intl
Tue 25/11
22:19-23:33
Nonstop2h 14m
San Pedro Sula Ramon Villeda
Tue 3/2
13:55-17:01
Nonstop2h 06m
Panama CitySan Pedro Sula
PTY - SAP
PTYSAP
Panama City Tocumen Intl
Tue 18/11
11:34-12:48
Nonstop2h 14m
San Pedro Sula Ramon Villeda
Mon 1/12
13:53-17:01
Nonstop2h 08m
Panama CityLos Angeles
PTY - LAX
PTYLAX
Panama City Tocumen Intl
Mon 12/1
16:41-23:33
1 stop9h 52m
Los Angeles
Fri 30/1
00:55-14:45
1 stop10h 50m
Panama CityLos Angeles
PTY - LAX
PTYLAX
Panama City Tocumen Intl
Mon 2/3
08:55-22:30
1 stop16h 35m
Los Angeles
Thu 5/3
00:55-14:45
1 stop10h 50m
Best time to book a flight from Panama
Have a flexible travel schedule? Discover the best time to fly from Panama with our price prediction graph.
Travel insights for flights from Panama
Get recent, data-driven insights about flights from Panama including ideal travel times, pricing trends, and more.
What is the cheapest month to book a flight from Panama?
Currently, December is the cheapest month in which you can book a flight from Panama (average of £484). Flying from Panama in August will prove the most costly (average of £775). There are multiple factors that influence the price of a flight so comparing airlines, departure airports and times can help keep costs down.
Which airlines fly from Panama?
Many airlines operate round-trip flights from Panama: United Airlines, Air France, KLM. These airlines fly to the following popular destinations: London.
What is the cheapest place to fly to from Panama?
The cheapest city to fly to from Panama is Medellín Jose Maria Cordova Intl, with prices starting at £50. Explore other affordable destinations below.
Airline reviews for flights from Panama
Get insights into the airlines that provide service from Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing airline for your flight from Panama. In the last 7 days, Cheapflights users made a total of 858,174 searches.
Read through reviews of airlines serving Panama, such as KLM, Air France, andUnited Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
Comfort
Entertainment
Food
Boarding
Crew
Reviews
Abisola,Oct 2025
LOS - CDG
Overall
Comfort
Entertainment
Food
Boarding
Crew
Reviews
Abisola,Oct 2025
LOS - CDG
Overall
Comfort
Entertainment
Food
Boarding
Crew
Reviews
Abisola,Oct 2025
LOS - CDG
Overall
Comfort
Entertainment
Food
Boarding
Crew
Reviews
Abisola,Oct 2025
LOS - CDG
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Direct flights from Central America
Book a direct flight from one of these other cities located in Central America.
Related info for your journey
Access useful and relevant information related to your journey from Panama. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 10 October 2025.
Fly with Cheapflights
Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.
How does Cheapflights help users find flights from Panama?
Cheapflights goes through 900+ travel sites to look for the best flight deals for flights from Panama. Too many options? Cheapflights also provides filters for things like airlines, price ranges, and number of stops to help you make a decision easily.
Why should you use Cheapflights to find cheap flight tickets from Panama?
By finding flights from multiple airlines and providers at completely no cost, Cheapflights helps millions of users like you annually find the best flights from Panama.
Can Cheapflights find flights from Panama with no change fees?
Certainly. Search results for flights from Panama shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.
Can Cheapflights notify me if prices for flights from Panama become cheaper?
Not ready to book yet? You can track prices for flights from Panama on Cheapflights with our Price Alerts feature and get notified when better prices are available.