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£128+ Cheap flights from Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 20/8. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
PTY — LHR
19 Aug — 26 Aug1
1 adult

What to know about flights from Panama

Discover essential information about flights departing from Panama, including flight schedules, destinations, airlines operating at the Panama airport, and any specific guidelines or requirements for travellers. Please note that the information is based on the most recent updates available. Data last updated 14 August 2025.

Good round-trip deal

£112 or less

Good one-way deal

£19 or less
Price to beat on a round-trip flight from Panama.
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Price to beat on a one-way flight from Panama.
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Find flights from Panama

Cheapest flights from Panama
Explore the most affordable flight options available from Panama. Find the lowest fares based on data from user searches, with prices last updated on 14 August 2025.

Thu 1/122:13PTY - MEX
Nonstop3h 47mCopa Airlines
Thu 8/102:00MEX - PTY
Nonstop3h 41mCopa Airlines
Deal found 14/8£206
Sat 13/911:36PTY - CUC
Nonstop1h 42mCopa Airlines
Sat 20/912:10CUC - PTY
Nonstop1h 48mCopa Airlines
Deal found 14/8£218
Mon 22/1222:00PTY - MEX
Nonstop4h 00mCopa Airlines
Thu 15/105:55MEX - PTY
Nonstop3h 40mCopa Airlines
Deal found 13/8£230
Sat 27/920:10PTY - MEX
1 stop15h 45mAvianca
Fri 3/1000:40MEX - PTY
1 stop14h 50mAvianca
Deal found 12/8£234
Sun 2/1122:03PTY - MEX
Nonstop3h 57mCopa Airlines
Mon 17/1102:00MEX - PTY
Nonstop3h 41mCopa Airlines
Deal found 13/8£238
Sat 10/111:36PTY - CUC
Nonstop1h 47mCopa Airlines
Fri 23/114:44CUC - PTY
Nonstop1h 41mCopa Airlines
Deal found 14/8£241
Mon 25/811:36PTY - CUC
Nonstop1h 45mCopa Airlines
Mon 8/915:13CUC - PTY
Nonstop1h 36mCopa Airlines
Deal found 13/8£246
Tue 26/807:45PTY - CUC
Nonstop1h 38mCopa Airlines
Mon 1/915:13CUC - PTY
Nonstop1h 36mCopa Airlines
Deal found 14/8£248
Fri 5/919:21PTY - MEX
Nonstop3h 44mCopa Airlines
Fri 12/915:30MEX - PTY
Nonstop3h 44mCopa Airlines
Deal found 14/8£253
Mon 17/1120:25PTY - MEX
1 stop5h 50mAvianca
Sat 22/1113:50MEX - PTY
1 stop10h 10mAvianca
Deal found 13/8£265
Sat 1/1111:36PTY - CUC
Nonstop1h 49mCopa Airlines
Sun 9/1112:14CUC - PTY
Nonstop1h 48mCopa Airlines
Deal found 14/8£267
Fri 5/919:21PTY - MEX
Nonstop3h 44mCopa Airlines
Mon 8/913:05MEX - PTY
Nonstop3h 44mCopa Airlines
Deal found 14/8£269

Find flights from Panama within your budget

 
Find flights departing from Panama that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 14 August 2025. In the last 7 days, Cheapflights users made a total of 858,174 searches

Fly to

Heathrow

Route

Depart

Return

Price

Panama CityMexico City

PTY - MEX

PTYMEX

Panama City Tocumen Intl

Thu 1/1

22:13-01:00

Nonstop3h 47m

Mexico City Benito Juarez

Fri 9/1

09:25-14:06

Nonstop3h 41m

£206

Panama CityMexico City

PTY - MEX

PTYMEX

Panama City Tocumen Intl

Thu 1/1

22:13-01:00

Nonstop3h 47m

Mexico City Benito Juarez

Mon 26/1

15:30-20:07

Nonstop3h 37m

£206

Panama CityMexico City

PTY - MEX

PTYMEX

Panama City Tocumen Intl

Thu 1/1

22:13-01:00

Nonstop3h 47m

Mexico City Benito Juarez

Thu 15/1

15:30-20:07

Nonstop3h 37m

£206

Panama CityMexico City

PTY - MEX

PTYMEX

Panama City Tocumen Intl

Sat 7/2

16:17-19:20

Nonstop4h 03m

Mexico City Benito Juarez

Sat 14/2

15:30-20:07

Nonstop3h 37m

£206

Panama CityCúcuta

PTY - CUC

PTYCUC

Panama City Tocumen Intl

Sun 12/10

09:20-11:12

Nonstop1h 52m

Cúcuta Camilo Dazo

Sat 18/10

12:11-13:58

Nonstop1h 47m

£218

Panama CityCúcuta

PTY - CUC

PTYCUC

Panama City Tocumen Intl

Wed 3/9

11:36-13:18

Nonstop1h 42m

Cúcuta Camilo Dazo

Wed 17/9

12:10-13:58

Nonstop1h 48m

£218

Panama CityCúcuta

PTY - CUC

PTYCUC

Panama City Tocumen Intl

Sat 13/9

11:36-13:18

Nonstop1h 42m

Cúcuta Camilo Dazo

Sat 20/9

12:10-13:58

Nonstop1h 48m

£218

Panama CityCúcuta

PTY - CUC

PTYCUC

Panama City Tocumen Intl

Tue 26/8

07:45-09:23

Nonstop1h 38m

Cúcuta Camilo Dazo

Sun 31/8

15:01-16:49

Nonstop1h 48m

£218

Panama CityMexico City

PTY - MEX

PTYMEX

Panama City Tocumen Intl

Fri 16/1

16:13-19:20

Nonstop4h 07m

Mexico City Benito Juarez

Sun 25/1

05:55-10:35

Nonstop3h 40m

£230

Panama CityMexico City

PTY - MEX

PTYMEX

Panama City Tocumen Intl

Fri 9/1

16:13-19:20

Nonstop4h 07m

Mexico City Benito Juarez

Thu 15/1

01:20-06:00

Nonstop3h 40m

£230

Flights are sorted by cheapest return flights first.

Deals found on 12/8

Showing 1-10 of 60 results
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Best time to book a flight from Panama

Have a flexible travel schedule? Discover the best time to fly from Panama with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama

Get recent, data-driven insights about flights from Panama including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Panama?

Currently, December is the cheapest month in which you can book a flight from Panama (average of £476). Flying from Panama in June will prove the most costly (average of £713). There are multiple factors that influence the price of a flight so comparing airlines, departure airports and times can help keep costs down.

Which airlines fly from Panama?

Many airlines operate round-trip flights from Panama: United Airlines, Air France, KLM. These airlines fly to the following popular destinations: London.

Copa Airlines
Copa Airlines
From £113
Air Panama
Air Panama
From £151
Wingo
Wingo
From £99
United Airlines
United Airlines
From £563

What is the cheapest place to fly to from Panama?

The cheapest city to fly to from Panama is David Enrique Malek, with prices starting at £19. Explore other affordable destinations below.

David Enrique Malek
David Enrique Malek
From £26
Medellín Jose Maria Cordova Intl
Medellín Jose Maria Cordova Intl
From £71
Panama City Tocumen Intl
Panama City Tocumen Intl
From £78
Cartagena Rafael Nunez
Cartagena Rafael Nunez
From £90

Airline reviews for flights from Panama

Get insights into the airlines that provide service from Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing airline for your flight from Panama. In the last 7 days, Cheapflights users made a total of 858,174 searches.
Read through reviews of airlines serving Panama, such as KLM, Air France, andUnited Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7.8
Good
1,381 reviews
Check prices

Boarding

7.8

Overall

7.8

Comfort

7.7

Food

7.3

Entertainment

7.1

Crew

8.4

Reviews

1 / 20
4.0
Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.
KLM
7.8
Good
1,381 reviews
KLM
7.8
Good
1,381 reviews
Check prices

Boarding

7.8

Overall

7.8

Comfort

7.7

Food

7.3

Entertainment

7.1

Crew

8.4

Reviews

1 / 20
4.0
Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.
Air France
7.4
Good
1,467 reviews
KLM
7.8
Good
1,381 reviews
Check prices

Boarding

7.8

Overall

7.8

Comfort

7.7

Food

7.3

Entertainment

7.1

Crew

8.4

Reviews

1 / 20
4.0
Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.
United Airlines
7.4
Good
8,916 reviews
KLM
7.8
Good
1,381 reviews
Check prices

Boarding

7.8

Overall

7.8

Comfort

7.7

Food

7.3

Entertainment

7.1

Crew

8.4

Reviews

1 / 20
4.0
Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.

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Direct flights from Central America

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Direct flights from Panama City

Related info for your journey

Access useful and relevant information related to your journey from Panama. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 14 August 2025.

  • What is the cheapest month to fly from Panama?

    At the present moment the cheapest month to fly from Panama is currently December; with June being the most expensive. Prices will vary depending on multiple factors such as booking in advance, airline and departure airports and times.

  • Where are the cheapest places to fly to from Panama?

    Check out the cheapest flights from Panama to embark to:
    Travel from Panama City to London from £625 round trip

  • How does Cheapflights help users find flights from Panama?

    Cheapflights goes through 900+ travel sites to look for the best flight deals for flights from Panama. Too many options? Cheapflights also provides filters for things like airlines, price ranges, and number of stops to help you make a decision easily.

  • Why should you use Cheapflights to find cheap flight tickets from Panama?

    By finding flights from multiple airlines and providers at completely no cost, Cheapflights helps millions of users like you annually find the best flights from Panama.

  • Can Cheapflights find flights from Panama with no change fees?

    Certainly. Search results for flights from Panama shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

  • Can Cheapflights notify me if prices for flights from Panama become cheaper?

    Not ready to book yet? You can track prices for flights from Panama on Cheapflights with our Price Alerts feature and get notified when better prices are available.

See more FAQs

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Panama?

Cheapflights goes through 900+ travel sites to look for the best flight deals for flights from Panama. Too many options? Cheapflights also provides filters for things like airlines, price ranges, and number of stops to help you make a decision easily.

Why should you use Cheapflights to find cheap flight tickets from Panama?

By finding flights from multiple airlines and providers at completely no cost, Cheapflights helps millions of users like you annually find the best flights from Panama.

Can Cheapflights find flights from Panama with no change fees?

Certainly. Search results for flights from Panama shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Panama become cheaper?

Not ready to book yet? You can track prices for flights from Panama on Cheapflights with our Price Alerts feature and get notified when better prices are available.

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