£72+ Cheap flights from Panama

This is the cheapest return flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 21/11. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
PTY — LHR
9 Nov — 16 Nov1
1 adult
1 adult, Economy

What to know about flights from Panama

Discover essential information about flights departing from Panama, including flight schedules, destinations, airlines operating at the Panama airport, and any specific guidelines or requirements for travellers. Please note that the information is based on the most recent updates available. Data last updated 10 October 2025.

Good round-trip deal

£121 or less

Good one-way deal

£68 or less
Price to beat on a round-trip flight from Panama.
Price to beat on a one-way flight from Panama.

Find flights from Panama

Enter your travel dates to find the best prices.

Cheapest flights from Panama
Explore the most affordable flight options available from Panama. Find the lowest fares based on data from user searches, with prices last updated on 10 October 2025.

Sat 1/1111:34PTY - SAP
Nonstop2h 14mCopa Airlines
Mon 10/1113:53SAP - PTY
Nonstop2h 08mCopa Airlines
Deal found 10/10£206
Tue 25/1111:34PTY - SAP
Nonstop2h 14mCopa Airlines
Mon 2/204:28SAP - PTY
Nonstop2h 11mCopa Airlines
Deal found 9/10£229
Tue 25/1115:50PTY - SAP
1 stop4h 00mAvianca
Tue 3/209:25SAP - PTY
1 stop8h 30mAvianca
Deal found 9/10£248
Thu 30/1011:34PTY - SAP
Nonstop2h 11mCopa Airlines
Tue 4/1104:26SAP - PTY
Nonstop2h 13mCopa Airlines
Deal found 10/10£251
Fri 19/1222:19PTY - SAP
Nonstop2h 14mCopa Airlines
Mon 29/1213:53SAP - PTY
Nonstop2h 08mCopa Airlines
Deal found 9/10£252
Tue 25/1115:50PTY - SAP
1 stop4h 00mMultiple Airlines
Tue 3/213:55SAP - PTY
Nonstop2h 06mMultiple Airlines
Deal found 9/10£369
Mon 2/311:57PTY - LAX
Nonstop7h 06mCopa Airlines
Thu 12/302:06LAX - PTY
Nonstop6h 19mCopa Airlines
Deal found 10/10£465
Wed 24/1218:24PTY - LAX
Nonstop7h 20mCopa Airlines
Thu 15/111:11LAX - PTY
Nonstop6h 28mCopa Airlines
Deal found 10/10£467
Mon 2/308:55PTY - LAX
1 stop16h 35mUnited Airlines
Fri 6/300:55LAX - PTY
1 stop10h 50mUnited Airlines
Deal found 10/10£469
Sun 7/1211:35PTY - LAX
1 stop9h 35mUnited Airlines
Mon 15/1218:45LAX - PTY
1 stop17h 00mUnited Airlines
Deal found 10/10£472
Sun 1/208:55PTY - LAX
1 stop13h 28mUnited Airlines
Sat 14/200:55LAX - PTY
1 stop10h 50mUnited Airlines
Deal found 9/10£476
Sun 18/118:24PTY - LAX
Nonstop7h 12mCopa Airlines
Sun 25/121:22LAX - PTY
Nonstop6h 15mCopa Airlines
Deal found 10/10£477

Find flights from Panama within your budget

 
Find flights departing from Panama that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 10 October 2025. In the last 7 days, Cheapflights users made a total of 858,174 searches

Fly to

Heathrow

Route

Depart

Return

Price

Panama CitySan Pedro Sula

PTY - SAP

PTYSAP

Panama City Tocumen Intl

Wed 5/11

11:34-12:48

Nonstop2h 14m

San Pedro Sula Ramon Villeda

Wed 12/11

13:53-17:01

Nonstop2h 08m

£206

Panama CitySan Pedro Sula

PTY - SAP

PTYSAP

Panama City Tocumen Intl

Sat 1/11

11:34-12:48

Nonstop2h 14m

San Pedro Sula Ramon Villeda

Wed 5/11

13:53-17:01

Nonstop2h 08m

£206

Panama CitySan Pedro Sula

PTY - SAP

PTYSAP

Panama City Tocumen Intl

Thu 30/10

11:34-12:45

Nonstop2h 11m

San Pedro Sula Ramon Villeda

Wed 5/11

13:53-17:01

Nonstop2h 08m

£206

Panama CitySan Pedro Sula

PTY - SAP

PTYSAP

Panama City Tocumen Intl

Tue 4/11

11:34-12:48

Nonstop2h 14m

San Pedro Sula Ramon Villeda

Sat 8/11

13:53-17:01

Nonstop2h 08m

£206

Panama CitySan Pedro Sula

PTY - SAP

PTYSAP

Panama City Tocumen Intl

Fri 31/10

11:34-12:45

Nonstop2h 11m

San Pedro Sula Ramon Villeda

Wed 5/11

13:53-17:01

Nonstop2h 08m

£206

Panama CitySan Pedro Sula

PTY - SAP

PTYSAP

Panama City Tocumen Intl

Sat 1/11

11:34-12:48

Nonstop2h 14m

San Pedro Sula Ramon Villeda

Mon 10/11

13:53-17:01

Nonstop2h 08m

£206

Panama CitySan Pedro Sula

PTY - SAP

PTYSAP

Panama City Tocumen Intl

Tue 25/11

22:19-23:33

Nonstop2h 14m

San Pedro Sula Ramon Villeda

Tue 3/2

13:55-17:01

Nonstop2h 06m

£229

Panama CitySan Pedro Sula

PTY - SAP

PTYSAP

Panama City Tocumen Intl

Tue 18/11

11:34-12:48

Nonstop2h 14m

San Pedro Sula Ramon Villeda

Mon 1/12

13:53-17:01

Nonstop2h 08m

£229

Panama CityLos Angeles

PTY - LAX

PTYLAX

Panama City Tocumen Intl

Mon 12/1

16:41-23:33

1 stop9h 52m

Los Angeles

Fri 30/1

00:55-14:45

1 stop10h 50m

£469

Panama CityLos Angeles

PTY - LAX

PTYLAX

Panama City Tocumen Intl

Mon 2/3

08:55-22:30

1 stop16h 35m

Los Angeles

Thu 5/3

00:55-14:45

1 stop10h 50m

£469

Flights are sorted by cheapest return flights first.

Deals found on 8/10

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from Panama

Have a flexible travel schedule? Discover the best time to fly from Panama with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama

Get recent, data-driven insights about flights from Panama including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Panama?

Currently, December is the cheapest month in which you can book a flight from Panama (average of £484). Flying from Panama in August will prove the most costly (average of £775). There are multiple factors that influence the price of a flight so comparing airlines, departure airports and times can help keep costs down.

Airline reviews for flights from Panama

Get insights into the airlines that provide service from Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing airline for your flight from Panama. In the last 7 days, Cheapflights users made a total of 858,174 searches.
Read through reviews of airlines serving Panama, such as KLM, Air France, andUnited Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Overall

7.7

Comfort

7.6

Entertainment

7.1

Food

7.2

Boarding

7.8

Crew

8.4

Reviews

1 / 20
2.0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.

Overall

7.7

Comfort

7.6

Entertainment

7.1

Food

7.2

Boarding

7.8

Crew

8.4

Reviews

1 / 20
2.0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.

Overall

7.7

Comfort

7.6

Entertainment

7.1

Food

7.2

Boarding

7.8

Crew

8.4

Reviews

1 / 20
2.0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.

Overall

7.7

Comfort

7.6

Entertainment

7.1

Food

7.2

Boarding

7.8

Crew

8.4

Reviews

1 / 20
2.0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Direct flights from Central America

Book a direct flight from one of these other cities located in Central America.

Related info for your journey

Access useful and relevant information related to your journey from Panama. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 10 October 2025.
  • What is the cheapest month to fly from Panama?

    At the present moment the cheapest month to fly from Panama is currently December; with August being the most expensive. Prices will vary depending on multiple factors such as booking in advance, airline and departure airports and times.

  • Where are the cheapest places to fly to from Panama?

    Check out the cheapest flights from Panama to embark to:
    Travel from Panama City to San Pedro Sula from £214 round trip
    Travel from Panama City to London from £643 round trip

  • How does Cheapflights help users find flights from Panama?

    Cheapflights goes through 900+ travel sites to look for the best flight deals for flights from Panama. Too many options? Cheapflights also provides filters for things like airlines, price ranges, and number of stops to help you make a decision easily.

  • Why should you use Cheapflights to find cheap flight tickets from Panama?

    By finding flights from multiple airlines and providers at completely no cost, Cheapflights helps millions of users like you annually find the best flights from Panama.

  • Can Cheapflights find flights from Panama with no change fees?

    Certainly. Search results for flights from Panama shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

  • Can Cheapflights notify me if prices for flights from Panama become cheaper?

    Not ready to book yet? You can track prices for flights from Panama on Cheapflights with our Price Alerts feature and get notified when better prices are available.

See more FAQs

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Panama?

Cheapflights goes through 900+ travel sites to look for the best flight deals for flights from Panama. Too many options? Cheapflights also provides filters for things like airlines, price ranges, and number of stops to help you make a decision easily.

Why should you use Cheapflights to find cheap flight tickets from Panama?

By finding flights from multiple airlines and providers at completely no cost, Cheapflights helps millions of users like you annually find the best flights from Panama.

Can Cheapflights find flights from Panama with no change fees?

Certainly. Search results for flights from Panama shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Panama become cheaper?

Not ready to book yet? You can track prices for flights from Panama on Cheapflights with our Price Alerts feature and get notified when better prices are available.

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.