£97+ Cheap flights from Santo Domingo

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 22/5. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
SDQ — LGW
21 Mar — 28 Mar1
1 adult
1 adult, Economy, 0 bags

What to know about flights from Santo Domingo

Discover essential information about flights departing from Santo Domingo, including flight schedules, destinations, airlines operating at the Santo Domingo airport, and any specific guidelines or requirements for travellers. Please note that the information is based on the most recent updates available. Data last updated 19 February 2026.

Cheapest one-way flight

£446

Most popular destination

Madrid Barajas (MAD)

Good round-trip deal

£201 or less

Good one-way deal

£82 or less
The cheapest one-way flight from Santo Domingo Las Americas is currently to Madrid Barajas.
Search Deals
Madrid Barajas (MAD) is currently the most popular flight destination from Santo Domingo Las Americas (average return price of £513).
Search Deals
Price to beat on a round-trip flight from Santo Domingo Las Americas.
Search Deals
Price to beat on a one-way flight from Santo Domingo Las Americas.
Search Deals

Find flights from Santo Domingo

Enter your travel dates to find the best prices.

Cheapest flights from Santo Domingo
Explore the most affordable flight options available from Santo Domingo. Find the lowest fares based on data from user searches, with prices last updated on 19 February 2026.

Tue 5/515:35
SDQ
-
MIA
Nonstop2h 20m
Multiple Airlines
Fri 8/517:18
MIA
-
SDQ
1 stop8h 27m
Multiple Airlines
Deal found 16/2£159
Mon 13/410:19
SDQ
-
MIA
Nonstop2h 20m
Multiple Airlines
Fri 17/417:18
MIA
-
SDQ
1 stop8h 27m
Multiple Airlines
Deal found 16/2£167
Mon 6/410:19
SDQ
-
MIA
Nonstop2h 20m
Multiple Airlines
Sun 12/416:02
MIA
-
SDQ
1 stop6h 13m
Multiple Airlines
Deal found 16/2£170
Fri 22/510:19
SDQ
-
MIA
Nonstop2h 20m
Arajet
Mon 25/514:09
MIA
-
SDQ
Nonstop2h 20m
Arajet
Deal found 17/2£171
Tue 24/306:10
SDQ
-
MIA
1 stop7h 17m
Multiple Airlines
Sat 28/313:55
MIA
-
SDQ
1 stop7h 45m
Multiple Airlines
Deal found 17/2£174
Tue 17/315:35
SDQ
-
MIA
Nonstop2h 20m
Multiple Airlines
Tue 24/314:57
MIA
-
SDQ
1 stop6h 43m
Multiple Airlines
Deal found 16/2£174
Fri 17/408:55
SDQ
-
MIA
1 stop6h 53m
Multiple Airlines
Tue 28/419:25
MIA
-
SDQ
Nonstop2h 20m
Multiple Airlines
Deal found 17/2£177
Fri 20/310:19
SDQ
-
MIA
Nonstop2h 20m
Multiple Airlines
Mon 23/318:53
MIA
-
SDQ
1 stop7h 32m
Multiple Airlines
Deal found 17/2£179
Tue 31/305:10
SDQ
-
MIA
1 stop7h 15m
Multiple Airlines
Tue 31/319:25
MIA
-
SDQ
Nonstop2h 20m
Multiple Airlines
Deal found 17/2£181
Wed 25/303:55
SDQ
-
MIA
1 stop8h 30m
Multiple Airlines
Fri 10/414:09
MIA
-
SDQ
Nonstop2h 20m
Multiple Airlines
Deal found 16/2£182
Wed 25/310:19
SDQ
-
MIA
Nonstop2h 20m
Multiple Airlines
Sun 29/316:02
MIA
-
SDQ
1 stop11h 58m
Multiple Airlines
Deal found 18/2£183
Tue 31/305:10
SDQ
-
MIA
1 stop7h 15m
Multiple Airlines
Sat 11/413:55
MIA
-
SDQ
1 stop7h 45m
Multiple Airlines
Deal found 17/2£184

Find flights from Santo Domingo within your budget

 
Find flights departing from Santo Domingo that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 19 February 2026. In the last 7 days, Cheapflights users made a total of 858,174 searches

Fly to

Gatwick

Route

Depart

Return

Price

Santo DomingoMiami

SDQ - MIA

SDQMIA

Santo Domingo Las Americas

Mon 16/3

10:19-12:39

Nonstop2h 20m

Miami

Mon 23/3

18:53-02:25

1 stop7h 32m

£159

Santo DomingoMiami

SDQ - MIA

SDQMIA

Santo Domingo Las Americas

Tue 5/5

15:35-17:55

Nonstop2h 20m

Miami

Wed 20/5

17:18-03:30

1 stop10h 12m

£159

Santo DomingoMiami

SDQ - MIA

SDQMIA

Santo Domingo Las Americas

Fri 1/5

01:40-12:25

1 stop10h 45m

Miami

Tue 12/5

19:25-21:45

Nonstop2h 20m

£167

Santo DomingoMiami

SDQ - MIA

SDQMIA

Santo Domingo Las Americas

Mon 13/4

10:19-12:39

Nonstop2h 20m

Miami

Fri 17/4

17:18-01:45

1 stop8h 27m

£167

Santo DomingoMiami

SDQ - MIA

SDQMIA

Santo Domingo Las Americas

Thu 23/4

17:02-19:22

Nonstop2h 20m

Miami

Sun 26/4

16:02-04:00

1 stop11h 58m

£170

Santo DomingoMiami

SDQ - MIA

SDQMIA

Santo Domingo Las Americas

Mon 4/5

09:30-17:23

1 stop7h 53m

Miami

Fri 15/5

14:09-16:29

Nonstop2h 20m

£170

Santo DomingoMiami

SDQ - MIA

SDQMIA

Santo Domingo Las Americas

Mon 6/4

10:19-12:39

Nonstop2h 20m

Miami

Sun 12/4

16:02-22:15

1 stop6h 13m

£170

Santo DomingoMiami

SDQ - MIA

SDQMIA

Santo Domingo Las Americas

Mon 6/4

10:19-12:39

Nonstop2h 20m

Miami

Fri 10/4

17:18-01:45

1 stop8h 27m

£170

Santo DomingoMiami

SDQ - MIA

SDQMIA

Santo Domingo Las Americas

Mon 6/4

10:19-12:39

Nonstop2h 20m

Miami

Wed 15/4

17:18-03:30

1 stop10h 12m

£170

Santo DomingoMiami

SDQ - MIA

SDQMIA

Santo Domingo Las Americas

Sat 4/4

15:35-17:55

Nonstop2h 20m

Miami

Sat 11/4

13:55-21:40

1 stop7h 45m

£170

Flights are sorted by cheapest return flights first.

Deals found on 16/2

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from Santo Domingo

Have a flexible travel schedule? Discover the best time to fly from Santo Domingo with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Santo Domingo

Get recent, data-driven insights about flights from Santo Domingo including ideal travel times, pricing trends, and more.

What are popular destinations to fly to from Santo Domingo?

If you’re flying from Santo Domingo, these routes are more frequently taken by airlines New York (240 flights per day), Miami (91 flights per day) and Madrid (70 flights per day).

Madrid Barajas
Madrid Barajas
From £446
Panama City Tocumen Intl
Panama City Tocumen Intl
From £81
Miami
Miami
From £233
Simpson Bay Princess Juliana
Simpson Bay Princess Juliana
From £82

What is the cheapest place to fly to from Santo Domingo?

The cheapest city to fly to from Santo Domingo is Panama City Tocumen Intl, with prices starting at £81. Explore other affordable destinations below.

Panama City Tocumen Intl
Panama City Tocumen Intl
From £81
Simpson Bay Princess Juliana
Simpson Bay Princess Juliana
From £82
New York
New York
From £147
Bogotá El Dorado
Bogotá El Dorado
From £196

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Direct flights from Dominican Republic

Book a direct flight from one of these other cities located in Dominican Republic.
Direct flights from Santo Domingo
Direct flights from Punta Cana
Direct flights from Puerto Plata
Direct flights from Santiago de los Caballeros
Direct flights from La Romana

Related info for your journey

Access useful and relevant information related to your journey from Santo Domingo. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 19 February 2026.

  • What are the most popular destinations to fly to from Santo Domingo?

    This month, the top selected destinations from Santo Domingo are Medellín Jose Maria Cordova Intl Airport, New York John F Kennedy Intl Airport, Newark Airport. Throughout the year, New York John F Kennedy Intl Airport, Newark Airport, Medellín Jose Maria Cordova Intl Airport are some of the top choices made by users flying from Santo Domingo.

  • What is the cheapest flight from Santo Domingo to anywhere?

    Users have flown out of Santo Domingo for as low as £81 to Panama City (prices may vary depending on the airline and departure time). On average, users have booked flights for £399 to fly from Santo Domingo.

  • What is the cheapest premium economy flight from Santo Domingo?

    Here are some of the cheapest offers we have found for the cheapest premium economy flights from Santo Domingo.
    Santo Domingo Las Americas to Panama City from £2,314

  • How does Cheapflights help users find flights from Santo Domingo?

    Cheapflights goes through 900+ travel sites to look for the best flight deals for flights from Santo Domingo. Too many options? Cheapflights also provides filters for things like airlines, price ranges, and number of stops to help you make a decision easily.

  • Why should you use Cheapflights to find cheap flight tickets from Santo Domingo?

    Cheapflights taps into our reliable network of hundreds of airlines and travel agencies to find the best deals for flights from Santo Domingo for you. Better yet — we are completely free to use.

  • Can Cheapflights find flights from Santo Domingo with no change fees?

    Certainly. Search results for flights from Santo Domingo shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

  • Can Cheapflights notify me if prices for flights from Santo Domingo become cheaper?

    Of course! You can now track prices for flights from Santo Domingo and get an alert from Cheapflights when they change. Click the bell icon next to the flight deals above and provide your email address to set up price alerts.

See more FAQs

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Santo Domingo?

Cheapflights goes through 900+ travel sites to look for the best flight deals for flights from Santo Domingo. Too many options? Cheapflights also provides filters for things like airlines, price ranges, and number of stops to help you make a decision easily.

Why should you use Cheapflights to find cheap flight tickets from Santo Domingo?

Cheapflights taps into our reliable network of hundreds of airlines and travel agencies to find the best deals for flights from Santo Domingo for you. Better yet — we are completely free to use.

Can Cheapflights find flights from Santo Domingo with no change fees?

Certainly. Search results for flights from Santo Domingo shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Santo Domingo become cheaper?

Of course! You can now track prices for flights from Santo Domingo and get an alert from Cheapflights when they change. Click the bell icon next to the flight deals above and provide your email address to set up price alerts.

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.