£123+ Cheap flights from Santo Domingo

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 18/1. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
SDQ — LGW
22 Jan — 29 Jan1
1 adult
1 adult, Economy, 0 bags

What to know about flights from Santo Domingo

Discover essential information about flights departing from Santo Domingo, including flight schedules, destinations, airlines operating at the Santo Domingo airport, and any specific guidelines or requirements for travellers. Please note that the information is based on the most recent updates available. Data last updated 23 December 2025.

Good one-way deal

£83 or less
Price to beat on a one-way flight from Santo Domingo Las Americas.
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Cheapest flights from Santo Domingo
Explore the most affordable flight options available from Santo Domingo. Find the lowest fares based on data from user searches, with prices last updated on 23 December 2025.

Fri 6/318:39SDQ - CTG
1 stop15h 02mCopa Airlines
Fri 13/309:22CTG - SDQ
1 stop5h 52mCopa Airlines
Deal found 22/12£202
Fri 23/119:05SDQ - CTG
1 stop14h 36mCopa Airlines
Fri 30/106:24CTG - SDQ
1 stop5h 45mCopa Airlines
Deal found 22/12£210
Wed 18/215:42SDQ - MIA
1 stop10h 11mDelta
Wed 25/206:00MIA - SDQ
1 stop7h 17mDelta
Deal found 21/12£221
Thu 5/314:13SDQ - GUA
2 stops9h 27mCopa Airlines
Tue 10/306:24GUA - SDQ
2 stops7h 50mCopa Airlines
Deal found 21/12£230
Sun 8/318:39SDQ - CTG
1 stop14h 27mCopa Airlines
Sun 15/306:25CTG - SDQ
1 stop5h 46mCopa Airlines
Deal found 22/12£233
Tue 17/306:00SDQ - GUA
2 stops17h 40mCopa Airlines
Tue 24/306:24GUA - SDQ
2 stops14h 16mCopa Airlines
Deal found 20/12£236
Mon 16/318:39SDQ - GUA
1 stop16h 55mCopa Airlines
Mon 23/310:34GUA - SDQ
1 stop13h 44mCopa Airlines
Deal found 22/12£239
Thu 5/308:48SDQ - MIA
1 stop13h 54mCopa Airlines
Wed 18/306:26MIA - SDQ
1 stop9h 48mCopa Airlines
Deal found 23/12£240
Sun 22/318:39SDQ - CTG
1 stop15h 02mCopa Airlines
Sun 29/306:19CTG - SDQ
1 stop5h 52mCopa Airlines
Deal found 22/12£241
Sun 1/306:00SDQ - CTG
1 stop9h 04mCopa Airlines
Sun 8/306:25CTG - SDQ
1 stop5h 46mCopa Airlines
Deal found 22/12£242
Thu 15/106:00SDQ - MIA
1 stop6h 32mCopa Airlines
Sun 25/105:26MIA - SDQ
1 stop11h 39mCopa Airlines
Deal found 22/12£242
Mon 16/218:39SDQ - GUA
2 stops29h 01mCopa Airlines
Mon 23/206:24GUA - SDQ
2 stops17h 53mCopa Airlines
Deal found 22/12£243

Find flights from Santo Domingo within your budget

 
Find flights departing from Santo Domingo that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 23 December 2025. In the last 7 days, Cheapflights users made a total of 858,174 searches

Fly to

Gatwick

Route

Depart

Return

Price

Santo DomingoCartagena

SDQ - CTG

SDQCTG

Santo Domingo Las Americas

Fri 20/2

18:39-08:41

1 stop15h 02m

Cartagena Rafael Nunez

Fri 27/2

06:25-13:09

1 stop5h 44m

£202

Santo DomingoCartagena

SDQ - CTG

SDQCTG

Santo Domingo Las Americas

Fri 6/3

18:39-08:41

1 stop15h 02m

Cartagena Rafael Nunez

Fri 13/3

06:25-22:40

1 stop15h 15m

£202

Santo DomingoCartagena

SDQ - CTG

SDQCTG

Santo Domingo Las Americas

Fri 6/2

19:05-08:41

1 stop14h 36m

Cartagena Rafael Nunez

Fri 13/2

09:42-18:05

1 stop7h 23m

£202

Santo DomingoCartagena

SDQ - CTG

SDQCTG

Santo Domingo Las Americas

Fri 27/2

18:39-08:41

1 stop15h 02m

Cartagena Rafael Nunez

Fri 6/3

09:22-16:14

1 stop5h 52m

£202

Santo DomingoCartagena

SDQ - CTG

SDQCTG

Santo Domingo Las Americas

Sun 22/2

11:57-23:00

1 stop12h 03m

Cartagena Rafael Nunez

Sun 1/3

06:25-13:11

1 stop5h 46m

£210

Santo DomingoCartagena

SDQ - CTG

SDQCTG

Santo Domingo Las Americas

Fri 10/4

08:43-14:02

1 stop6h 19m

Cartagena Rafael Nunez

Fri 17/4

09:46-22:51

1 stop12h 05m

£210

Santo DomingoGuatemala City

SDQ - GUA

SDQGUA

Santo Domingo Las Americas

Sat 11/4

12:08-21:41

2 stops11h 33m

Guatemala City La Aurora

Fri 17/4

02:31-13:12

1 stop8h 41m

£230

Santo DomingoGuatemala City

SDQ - GUA

SDQGUA

Santo Domingo Las Americas

Mon 20/4

18:37-09:36

1 stop16h 59m

Guatemala City La Aurora

Mon 27/4

06:24-02:20

2 stops17h 56m

£230

Santo DomingoGuatemala City

SDQ - GUA

SDQGUA

Santo Domingo Las Americas

Tue 10/2

08:50-21:40

2 stops14h 50m

Guatemala City La Aurora

Mon 16/2

02:26-10:50

1 stop6h 24m

£230

Santo DomingoGuatemala City

SDQ - GUA

SDQGUA

Santo Domingo Las Americas

Thu 16/4

14:12-23:10

1 stop10h 58m

Guatemala City La Aurora

Thu 23/4

06:24-16:14

2 stops7h 50m

£230

Flights are sorted by cheapest return flights first.

Deals found on 21/12

Showing 1-10 of 60 results
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Best time to book a flight from Santo Domingo

Have a flexible travel schedule? Discover the best time to fly from Santo Domingo with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Santo Domingo

Get recent, data-driven insights about flights from Santo Domingo including ideal travel times, pricing trends, and more.

What are popular destinations to fly to from Santo Domingo?

If you’re flying from Santo Domingo, these routes are more frequently taken by airlines New York (374 flights per day), Miami (84 flights per day) and Orlando (68 flights per day).

Simpson Bay Princess Juliana
Simpson Bay Princess Juliana
From £83
Miami
Miami
From £147
Madrid Barajas
Madrid Barajas
From £232
Atlanta Hartsfield-Jackson
Atlanta Hartsfield-Jackson
From £622

What is the cheapest place to fly to from Santo Domingo?

The cheapest city to fly to from Santo Domingo is Simpson Bay Princess Juliana, with prices starting at £83. Explore other affordable destinations below.

Simpson Bay Princess Juliana
Simpson Bay Princess Juliana
From £83
Miami
Miami
From £147
Madrid Barajas
Madrid Barajas
From £232
Atlanta Hartsfield-Jackson
Atlanta Hartsfield-Jackson
From £622

Browse thousands of different options on Cheapflights for your next trip

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Direct flights from Dominican Republic

Book a direct flight from one of these other cities located in Dominican Republic.
Direct flights from Santo Domingo
Direct flights from Punta Cana
Direct flights from Puerto Plata
Direct flights from Santiago de los Caballeros

Related info for your journey

Access useful and relevant information related to your journey from Santo Domingo. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 23 December 2025.

  • What are the most popular destinations to fly to from Santo Domingo?

    This month, the top selected destinations from Santo Domingo are New York John F Kennedy Intl Airport, Newark Airport, Boston. Throughout the year, New York John F Kennedy Intl Airport, Newark Airport, Medellín Jose Maria Cordova Intl Airport are some of the top choices made by users flying from Santo Domingo.

  • What is the cheapest flight from Santo Domingo to anywhere?

    Users have flown out of Santo Domingo for as low as £83 to Simpson Bay (prices may vary depending on the airline and departure time). On average, users have booked flights for £554 to fly from Santo Domingo.

  • What is the cheapest premium economy flight from Santo Domingo?

    Here are some of the cheapest offers we have found for the cheapest premium economy flights from Santo Domingo.
    Santo Domingo Las Americas to New York John F Kennedy Intl Airport from £1,373
    Santo Domingo Las Americas to Panama City from £2,334

  • How does Cheapflights help users find flights from Santo Domingo?

    Cheapflights goes through 900+ travel sites to look for the best flight deals for flights from Santo Domingo. Too many options? Cheapflights also provides filters for things like airlines, price ranges, and number of stops to help you make a decision easily.

  • Why should you use Cheapflights to find cheap flight tickets from Santo Domingo?

    Cheapflights taps into our reliable network of hundreds of airlines and travel agencies to find the best deals for flights from Santo Domingo for you. Better yet — we are completely free to use.

  • Can Cheapflights find flights from Santo Domingo with no change fees?

    Certainly. Search results for flights from Santo Domingo shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

  • Can Cheapflights notify me if prices for flights from Santo Domingo become cheaper?

    Of course! You can now track prices for flights from Santo Domingo and get an alert from Cheapflights when they change. Click the bell icon next to the flight deals above and provide your email address to set up price alerts.

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Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Santo Domingo?

Cheapflights goes through 900+ travel sites to look for the best flight deals for flights from Santo Domingo. Too many options? Cheapflights also provides filters for things like airlines, price ranges, and number of stops to help you make a decision easily.

Why should you use Cheapflights to find cheap flight tickets from Santo Domingo?

Cheapflights taps into our reliable network of hundreds of airlines and travel agencies to find the best deals for flights from Santo Domingo for you. Better yet — we are completely free to use.

Can Cheapflights find flights from Santo Domingo with no change fees?

Certainly. Search results for flights from Santo Domingo shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Santo Domingo become cheaper?

Of course! You can now track prices for flights from Santo Domingo and get an alert from Cheapflights when they change. Click the bell icon next to the flight deals above and provide your email address to set up price alerts.

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