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Cheap flights from Panama City to Cape Town from £527

PTY — CPT
21 Oct — 28 Oct1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Panama City to Cape Town

Enter your travel dates to find the best prices.

Cheapest flights from Panama City to Cape Town

Fri 30/1009:30 -
2 stops48h 50m
Tue 10/1120:50 -
1 stop30h 45m
Deal found 17/9£729
Wed 21/1009:45 -
1 stop24h 25m
Wed 28/1020:50 -
1 stop29h 12m
Deal found 21/9£734
Sun 18/1009:45 -
1 stop24h 25m
Sun 25/1020:50 -
1 stop40h 23m
Deal found 21/9£735
Sun 1/1122:29 -
1 stop34h 41m
Sun 8/1119:10 -
2 stops32h 21m
Deal found 17/9£759
Fri 25/908:11 -
2 stops25h 59m
Thu 15/1019:50 -
2 stops48h 41m
Deal found 18/9£814
Thu 5/1110:00 -
2 stops43h 40m
Mon 30/1120:50 -
2 stops47h 41m
Deal found 20/9£822

Find flight deals from Panama City to Cape Town

Round-trip from

£729

One-way from

£527

Popular in

March

Cheapest in

January

Average price

£1,560
United Airlines
  • United Airlines
  • 30/10-10/11
  • 3 total stops
  • 79h 35m total
  • Panama City to Cape Town
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United Airlines
  • United Airlines
  • 11/10-31/12
  • 1 total stop
  • 24h 25m total
  • Panama City to Cape Town
Search Deals
Highest demand for flights based on searches. 9% potential increase in price (£81 potential increase over avg. return price).
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Cheapest flight prices on average. 4% potential price decrease (£34 potential savings vs. average return price).
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Average for round-trip flights in September 2026
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Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Panama City to Cape Town that are best for you.

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Route

Depart

Return

Price

Cheapest return flight
Fastest return journey

Panama CityCape Town

PTY Panama City Tocumen Intl - CPT Cape Town Intl

PTYCPT

Panama City Tocumen Intl

Sun 11/10

09:45-17:10

1 stop24h 25m

Cape Town Intl

Wed 31/12

00:00-17:00

Nonstop0h 00m

£527

Panama CityCape Town

PTY Panama City Tocumen Intl - CPT Cape Town Intl

PTYCPT

Panama City Tocumen Intl

Fri 30/10

09:30-17:20

2 stops48h 50m

Cape Town Intl

Tue 10/11

20:50-20:37

2 stops30h 47m

£732

Panama CityCape Town

PTY Panama City Tocumen Intl - CPT Cape Town Intl

PTYCPT

Panama City Tocumen Intl

Wed 21/10

09:45-17:10

1 stop24h 25m

Cape Town Intl

Wed 28/10

20:50-05:33

2 stops39h 43m

£734

Panama CityCape Town

PTY Panama City Tocumen Intl - CPT Cape Town Intl

PTYCPT

Panama City Tocumen Intl

Wed 3/2

22:29-16:10

1 stop34h 41m

Cape Town Intl

Wed 17/2

20:50-20:02

1 stop30h 12m

£734

Panama CityCape Town

PTY Panama City Tocumen Intl - CPT Cape Town Intl

PTYCPT

Panama City Tocumen Intl

Sun 18/10

09:45-17:10

1 stop24h 25m

Cape Town Intl

Sun 25/10

20:50-20:27

3 stops30h 37m

£735

Panama CityCape Town

PTY Panama City Tocumen Intl - CPT Cape Town Intl

PTYCPT

Panama City Tocumen Intl

Sun 1/11

08:55-16:10

2 stops48h 15m

Cape Town Intl

Sun 8/11

19:10-20:31

2 stops32h 21m

£759

Panama CityCape Town

PTY Panama City Tocumen Intl - CPT Cape Town Intl

PTYCPT

Panama City Tocumen Intl

Thu 5/11

10:00-12:40

2 stops43h 40m

Cape Town Intl

Mon 30/11

20:50-13:31

2 stops47h 41m

£822

Panama CityCape Town

PTY Panama City Tocumen Intl - CPT Cape Town Intl

PTYCPT

Panama City Tocumen Intl

Sun 22/11

16:41-16:10

2 stops40h 29m

Cape Town Intl

Sat 5/12

20:50-10:46

2 stops44h 56m

£904

Flights are sorted by cheapest return flights first.

Deals found on 19/9

Sorted by cheapest first

Best time to book a flight from Panama City to Cape Town

Have a flexible travel schedule? Discover the best time to fly to Cape Town from Panama City with our price prediction graph.
Estimated return price

Cheapflights Insights

Everything you need to know about your flight from Panama City to Cape Town

What is the cheapest month to book a flight from Panama City to Cape Town?

Currently, January is the cheapest month in which you can book a flight from Panama City to Cape Town (average of £718). Flying from Panama City to Cape Town in March is currently the most expensive (average of £1,564). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

  • How long is the flight from Panama City to Cape Town?

    Airlines like United Airlines fly from Panama City to Cape Town in about 48h 50m. The time it takes to get you to your destination can typically vary by up to . The distance from Panama City to Cape Town is about 7018 mi.

  • Can I find deals for flights from Panama City to Cape Town that include hotel bookings?

    Yes. In addition to deals on Panama City to Cape Town flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Cape Town?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Cape Town.

  • Can I find deals for business class flights from Panama City to Cape Town?

    Yes. Cheapflights offers flight deals from Panama City to Cape Town by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Cape Town?

    Currently, January is the cheapest month in which you can book a flight from Panama City to Cape Town (average of £718). Flying from Panama City to Cape Town in March is currently the most expensive (average of £1,564). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Cape Town?

Book flights to Cape Town if you plan to visit one of these locations
Somerset West
Gordon's Bay
Simon's Town
Stellenbosch
Franschhoek
Hermanus
Paarl

Browse thousands of different options on Cheapflights for your next trip

Fly with Cheapflights

How does Cheapflights help users find flights from Panama City to Cape Town?

Cheapflights makes it easy to find Panama City to Cape Town flights by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

Why should you use Cheapflights to find cheap flight tickets from Panama City to Cape Town?

Cheapflights taps into our reliable network of hundreds of airlines and travel agencies to find the best deals for flights from Panama City to Cape Town for you. Better yet — we are completely free to use.

Can Cheapflights find flights from Panama City to Cape Town with no change fees?

Certainly. Search results for flights to Cape Town from Panama City shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Panama City to Cape Town become cheaper?

Of course! You can now track prices for flights from Panama City to Cape Town and get an alert from Cheapflights when they change. Have a valid email address ready and click the bell icon next to the flight deals above to set up your price alerts.

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