How long is the flight from Santa Ana, California to Des Moines?

For as low as £267, United Airlines can have you in Des Moines from Santa Ana, California in 6h 35m. There are 1425 mi between Santa Ana, California and Des Moines. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.

In terms of precipitation, rainfall in Des Moines ranges from 25.0 - 125.0 inches per month. June is typically the wettest month, when rainfall can reach 125.0 mm. January is typically the driest time to visit Des Moines when rainfall is around 25.0 mm.

If weather is an important factor for your trip to Des Moines, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 25.0 C. Travellers hoping to avoid the cold should look outside of January, when temperatures are typically at their lowest (around -5.0 C).

What is the cheapest time of day to fly from SNA to DSM?

When flying from Santa Ana, California to Des Moines, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Can I find deals for flights from Santa Ana to Des Moines that include hotel bookings?

Yes. In addition to deals on Santa Ana to Des Moines flights, Cheapflights offers holiday packages that include both flights and hotel.

How can I find direct flights from Santa Ana to Des Moines?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Ana to Des Moines.

Can I find deals for business class flights from Santa Ana to Des Moines?

Yes. Cheapflights offers flight deals from Santa Ana to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

£132+ Cheap Flights from Santa Ana, California to Des Moines

Cheap flight deals from Santa Ana to Des Moines

Enter your travel dates to find the best prices.

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Cheapest flights from Santa Ana to Des Moines
Explore the most affordable flight options available from Santa Ana to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 6 November 2026.

Wed 25/1110:47 -

1 stop9h 08m

Wed 2/1217:15 -

1 stop5h 54m

Deal found 3/11£263

Thu 3/1207:00 -

2 stops13h 38m

Fri 4/1210:30 -

2 stops12h 34m

Deal found 3/11£272

Thu 10/1207:00 -

2 stops11h 39m

Sat 12/1212:38 -

2 stops11h 52m

Deal found 5/11£295

Thu 26/1107:15 -

2 stops13h 20m

Thu 3/1211:01 -

2 stops13h 29m

Deal found 3/11£317

Thu 10/1207:00 -

2 stops11h 39m

Sun 13/1205:20 -

2 stops13h 00m

Deal found 5/11£324

Wed 2/1207:00 -

2 stops11h 39m

Sat 5/1206:09 -

2 stops12h 11m

Deal found 4/11£328

Wed 2/1211:30 -

2 stops7h 20m

Sat 5/1207:00 -

2 stops8h 25m

Deal found 3/11£329

Mon 7/1211:30 -

2 stops7h 20m

Thu 10/1207:00 -

2 stops7h 30m

Deal found 2/11£367

Thu 17/1212:30 -

2 stops7h 35m

Thu 24/1212:05 -

2 stops7h 20m

Deal found 2/11£375

Tue 1/1207:00 -

2 stops12h 31m

Tue 8/1211:38 -

2 stops12h 43m

Deal found 2/11£377

Find flight deals from Santa Ana to Des Moines

Round-trip from	£263
One-way from	£132
Popular in	November
Cheapest in	January
Average price	£343

United Airlines
25/11-2/12
2 total stops
15h 02m total
Santa Ana to Des Moines

Search Deals

Delta
25/12-31/12
1 total stop
8h 33m total
Santa Ana to Des Moines

Search Deals

Highest demand for flights based on searches. 13% potential increase in price (£25 potential increase over avg. return price).

Search Deals

Cheapest flight prices on average. 4% potential price decrease (£8 potential savings vs. average return price).

Search Deals

Average for round-trip flights in November 2026

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Santa Ana to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

Santa AnaDes Moines

SNA Santa Ana J. Wayne/Orange Cnty - DSM Des Moines

SNADSM

Santa Ana J. Wayne/Orange Cnty

Fri 25/12

12:05-22:38

1 stop8h 33m

Des Moines

Wed 31/12

00:00-22:00

Nonstop0h 00m

£132

Santa AnaDes Moines

SNA Santa Ana J. Wayne/Orange Cnty - DSM Des Moines

SNADSM

Santa Ana J. Wayne/Orange Cnty

Fri 15/1

11:35-21:40

2 stops8h 05m

Des Moines

Wed 31/12

00:00-22:00

Nonstop0h 00m

£156

Santa AnaDes Moines

SNA Santa Ana J. Wayne/Orange Cnty - DSM Des Moines

SNADSM

Santa Ana J. Wayne/Orange Cnty

Mon 25/1

06:49-16:11

1 stop7h 22m

Des Moines

Wed 31/12

00:00-22:00

Nonstop0h 00m

£173

Fastest return journey

Santa AnaDes Moines

SNA Santa Ana J. Wayne/Orange Cnty - DSM Des Moines

SNADSM

Santa Ana J. Wayne/Orange Cnty

Fri 1/1

08:45-16:16

1 stop5h 31m

Des Moines

Wed 31/12

00:00-22:00

Nonstop0h 00m

£173

Santa AnaDes Moines

SNA Santa Ana J. Wayne/Orange Cnty - DSM Des Moines

SNADSM

Santa Ana J. Wayne/Orange Cnty

Sun 7/3

19:05-10:20

2 stops13h 15m

Des Moines

Wed 31/12

00:00-22:00

Nonstop0h 00m

£181

Santa AnaDes Moines

SNA Santa Ana J. Wayne/Orange Cnty - DSM Des Moines

SNADSM

Santa Ana J. Wayne/Orange Cnty

Sun 24/1

07:45-22:16

2 stops12h 31m

Des Moines

Wed 31/12

00:00-22:00

Nonstop0h 00m

£226

Santa AnaDes Moines

SNA Santa Ana J. Wayne/Orange Cnty - DSM Des Moines

SNADSM

Santa Ana J. Wayne/Orange Cnty

Sun 27/12

11:55-23:35

2 stops9h 40m

Des Moines

Wed 31/12

00:00-22:00

Nonstop0h 00m

£238

Santa AnaDes Moines

SNA Santa Ana J. Wayne/Orange Cnty - DSM Des Moines

SNADSM

Santa Ana J. Wayne/Orange Cnty

Wed 25/11

10:47-21:55

1 stop9h 08m

Des Moines

Wed 2/12

17:15-21:09

1 stop5h 54m

£263

Santa AnaDes Moines

SNA Santa Ana J. Wayne/Orange Cnty - DSM Des Moines

SNADSM

Santa Ana J. Wayne/Orange Cnty

Tue 12/1

08:10-16:12

1 stop6h 02m

Des Moines

Tue 19/1

06:45-17:43

2 stops12h 58m

£267

Santa AnaDes Moines

SNA Santa Ana J. Wayne/Orange Cnty - DSM Des Moines

SNADSM

Santa Ana J. Wayne/Orange Cnty

Thu 10/12

08:55-16:13

1 stop5h 18m

Des Moines

Sat 12/12

13:15-21:09

2 stops9h 54m

£267

Flights are sorted by cheapest return flights first.

Deals found on 3/11

Showing 1-10 of 20 resultsSorted by cheapest first

Best time to book a flight from Santa Ana to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Santa Ana with our price prediction graph.

SNA-DSM

Estimated return price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Ana to Des Moines

What is the cheapest month to book a flight from Santa Ana, California to Des Moines?

Currently, January is the cheapest month in which you can book a flight from Santa Ana, California to Des Moines (average of £130). Flying from Santa Ana, California to Des Moines in November is currently the most expensive (average of £343). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost for a return flight from Santa Ana, California to Des Moines?

Airfare is typical for this route at the moment.

Santa Ana, California to Des Moines flights typically cost between £210 and £687 in November.
The cheapest return price found within the last 5 days was £263 on United Airlines (25 Nov–2 Dec).

Related info for your journey

How long is the flight from Santa Ana, California to Des Moines?
For as low as £267, United Airlines can have you in Des Moines from Santa Ana, California in 6h 35m. There are 1425 mi between Santa Ana, California and Des Moines. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.
Can I find deals for flights from Santa Ana to Des Moines that include hotel bookings?
Yes. In addition to deals on Santa Ana to Des Moines flights, Cheapflights offers holiday packages that include both flights and hotel.
How can I find direct flights from Santa Ana to Des Moines?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Ana to Des Moines.
Can I find deals for business class flights from Santa Ana to Des Moines?
Yes. Cheapflights offers flight deals from Santa Ana to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Santa Ana, California to Des Moines?
Currently, January is the cheapest month in which you can book a flight from Santa Ana, California to Des Moines (average of £130). Flying from Santa Ana, California to Des Moines in November is currently the most expensive (average of £343). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Cheap flights from Santa Ana, California to Des Moines from £132

This is the cheapest retur flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 25/12. Fares are subject to change and may not be available on all flights or dates of travel.

Cheap flight deals from Santa Ana to Des Moines

Cheapest flights from Santa Ana to Des MoinesExplore the most affordable flight options available from Santa Ana to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 6 November 2026.

Explore the most affordable flight options available from Santa Ana to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 6 November 2026.

Best flights from Santa Ana to Des MoinesDiscover carefully curated flight deals from Santa Ana to Des Moines that have cost, travel time, and stopovers in mind to ensure you get the best travel experience. Data last updated 6 November 2026.

Discover carefully curated flight deals from Santa Ana to Des Moines that have cost, travel time, and stopovers in mind to ensure you get the best travel experience. Data last updated 6 November 2026.

Last-minute flights from Santa Ana to Des MoinesDiscover last-minute flight deals from Santa Ana to Des Moines. Data last updated 6 November 2026 and is based on user searches.

Discover last-minute flight deals from Santa Ana to Des Moines. Data last updated 6 November 2026 and is based on user searches.

One-way flights from Santa Ana to Des MoinesSearch for one-way flight options from Santa Ana to Des Moines. Find affordable one-way fares based on user searches. Data last updated 6 November 2026.

Search for one-way flight options from Santa Ana to Des Moines. Find affordable one-way fares based on user searches. Data last updated 6 November 2026.

Find flight deals from Santa Ana to Des Moines

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Cheapflights Fare Finder

Use the filters below to find and compare flights from Santa Ana to Des Moines that are best for you.

Best time to book a flight from Santa Ana to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Santa Ana with our price prediction graph.

Cheapflights Insights

What is the cheapest month to book a flight from Santa Ana, California to Des Moines?

How much does it cost for a return flight from Santa Ana, California to Des Moines?

Airfare is typical for this route at the moment.

Santa Ana, California to Des Moines flights typically cost between £210 and £687 in November.The cheapest return price found within the last 5 days was £263 on United Airlines (25 Nov–2 Dec).

Related info for your journey

How long is the flight from Santa Ana, California to Des Moines?

Can I find deals for flights from Santa Ana to Des Moines that include hotel bookings?

How can I find direct flights from Santa Ana to Des Moines?

Can I find deals for business class flights from Santa Ana to Des Moines?

What is the cheapest month to book a flight from Santa Ana, California to Des Moines?

Browse thousands of different options on Cheapflights for your next trip

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How does Cheapflights help users find flights from Santa Ana to Des Moines?

Why should you use Cheapflights to find cheap flight tickets from Santa Ana to Des Moines?

Can Cheapflights find flights from Santa Ana to Des Moines with no change fees?

Can Cheapflights notify me if prices for flights from Santa Ana to Des Moines become cheaper?

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Cheapest flights from Santa Ana to Des Moines
Explore the most affordable flight options available from Santa Ana to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 6 November 2026.

Best flights from Santa Ana to Des Moines
Discover carefully curated flight deals from Santa Ana to Des Moines that have cost, travel time, and stopovers in mind to ensure you get the best travel experience. Data last updated 6 November 2026.

Last-minute flights from Santa Ana to Des Moines
Discover last-minute flight deals from Santa Ana to Des Moines. Data last updated 6 November 2026 and is based on user searches.

One-way flights from Santa Ana to Des Moines
Search for one-way flight options from Santa Ana to Des Moines. Find affordable one-way fares based on user searches. Data last updated 6 November 2026.

Santa Ana, California to Des Moines flights typically cost between £210 and £687 in November.
The cheapest return price found within the last 5 days was £263 on United Airlines (25 Nov–2 Dec).