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Cheap flights from Southampton to Florida Keys from £475

This is the cheapest retur flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 28/10. Fares are subject to change and may not be available on all flights or dates of travel.
SOU — EYW
15 Oct — 22 Oct1
1 adult
1 adult, Economy

Cheap flight deals from Southampton to Florida Keys

Keep the following information in mind while searching for Southampton to Florida Keys flight deals. Data was last updated 15 September 2025.

Round-trip from

£475

Popular in

December

Cheapest in

September

Average price

£402
Delta
  • Delta
  • 28/10-4/11
  • 4 total stops
  • 38h 48m total
  • Southampton to Florida Keys
Search Deals
Highest demand for flights based on searches. 2% potential increase in price (£9 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease (£10 potential savings vs. average return price).
Search Deals
Average for round-trip flights in September 2025
Search Deals

Find flight deals from Southampton to Florida Keys

Cheapest flights from Southampton to Florida Keys
Explore the most affordable flight options available from Southampton to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 15 September 2025.

Tue 28/1008:40SOU - MIA
2 stops19h 49mDelta
Tue 4/1108:11MIA - SOU
2 stops18h 59mDelta
Deal found 12/9£475
Wed 29/1008:40SOU - MIA
2 stops28h 55mKLM
Wed 5/1112:15MIA - SOU
2 stops15h 05mKLM
Deal found 14/9£476
Thu 30/1018:05SOU - MIA
1 stop25h 45mKLM
Thu 6/1111:16MIA - SOU
2 stops15h 49mKLM
Deal found 12/9£490
Tue 11/1117:30SOU - MIA
2 stops30h 21mDelta
Tue 25/1111:27MIA - SOU
2 stops24h 33mDelta
Deal found 14/9£505
Tue 28/1016:05SOU - MIA
1 stop30h 05mAer Lingus
Tue 4/1117:10MIA - SOU
2 stops17h 25mAer Lingus
Deal found 12/9£526
Mon 10/1108:40SOU - MIA
2 stops19h 33mDelta
Sat 22/1108:20MIA - SOU
2 stops19h 30mDelta
Deal found 14/9£535
Mon 10/1118:05SOU - MIA
1 stop25h 45mDelta
Thu 27/1107:55MIA - SOU
2 stops28h 05mDelta
Deal found 14/9£547
Tue 11/1117:30SOU - MIA
2 stops30h 21mDelta
Wed 26/1111:27MIA - SOU
2 stops15h 53mDelta
Deal found 14/9£551
Sun 12/1018:25SOU - MIA
2 stops27h 45mVirgin Atlantic
Sun 19/1006:00MIA - SOU
2 stops21h 45mVirgin Atlantic
Deal found 14/9£561

Cheapflights Fare Finder

 
Customise your flight search to find flights from Southampton to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 15 September 2025.
Use the filters below to find and compare flights from Southampton to Florida Keys that are best for you.

Fly from

Southampton

Fly to

Florida Keys

Route

Depart

Return

Price

SouthamptonMiami

SOU - MIA

SOUMIA

Southampton Eastleigh

Tue 28/10

08:40-00:29

2 stops19h 49m

Miami

Tue 4/11

08:11-08:10

2 stops18h 59m

£475

SouthamptonMiami

SOU - MIA

SOUMIA

Southampton Eastleigh

Wed 29/10

08:40-09:35

2 stops28h 55m

Miami

Wed 5/11

12:15-08:20

2 stops15h 05m

£476

SouthamptonMiami

SOU - MIA

SOUMIA

Southampton Eastleigh

Thu 30/10

18:05-15:50

1 stop25h 45m

Miami

Thu 6/11

11:16-08:05

2 stops15h 49m

£490

SouthamptonMiami

SOU - MIA

SOUMIA

Southampton Eastleigh

Wed 29/10

17:30-15:50

1 stop26h 20m

Miami

Wed 5/11

07:10-08:20

2 stops20h 10m

£501

SouthamptonMiami

SOU - MIA

SOUMIA

Southampton Eastleigh

Mon 10/11

08:40-23:13

2 stops19h 33m

Miami

Mon 24/11

11:27-08:10

2 stops15h 43m

£505

SouthamptonMiami

SOU - MIA

SOUMIA

Southampton Eastleigh

Tue 11/11

08:40-23:13

2 stops19h 33m

Miami

Mon 24/11

11:27-08:10

2 stops15h 43m

£505

SouthamptonMiami

SOU - MIA

SOUMIA

Southampton Eastleigh

Tue 11/11

17:30-18:51

2 stops30h 21m

Miami

Tue 25/11

11:27-17:00

2 stops24h 33m

£505

SouthamptonMiami

SOU - MIA

SOUMIA

Southampton Eastleigh

Tue 28/10

16:05-18:10

1 stop30h 05m

Miami

Tue 4/11

17:10-15:35

2 stops17h 25m

£526

SouthamptonMiami

SOU - MIA

SOUMIA

Southampton Eastleigh

Mon 10/11

08:40-23:13

2 stops19h 33m

Miami

Sat 22/11

08:20-08:50

2 stops19h 30m

£535

SouthamptonMiami

SOU - MIA

SOUMIA

Southampton Eastleigh

Sat 7/3

09:25-14:50

1 stop34h 25m

Miami

Wed 11/3

07:00-08:20

2 stops21h 20m

£537

Flights are sorted by cheapest return flights first.

Deals found on 14/9

Showing 1-10 of 12 results
1
2

Best time to book a flight from Southampton to Florida Keys

Have a flexible travel schedule? Discover the best time to fly to Florida Keys from Southampton with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Southampton to Florida Keys
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Southampton to Florida Keys. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Southampton to Florida Keys?

    For a flight from Southampton to Florida Keys, you will be flying from Eastleigh. Southampton Eastleigh (SOU) is just 3.5 mi from the center of the city.

  • How long is the flight from Southampton to Florida Keys?

    A quick flight from Southampton to Florida Keys can take about 19h 49m. Delta provides one of the quickest options available for as low as £475. Airlines will cover a distance of 4381 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Southampton to Florida Keys that include hotel bookings?

    Yes. In addition to deals on Southampton to Florida Keys flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Southampton to Florida Keys?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Southampton to Florida Keys.

  • Can I find deals for business class flights from Southampton to Florida Keys?

    Yes. Cheapflights offers flight deals from Southampton to Florida Keys by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Fly with Cheapflights

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How does Cheapflights help users find flights from Southampton to Florida Keys?

Deals for Southampton to Florida Keys flights are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose better, like price, airport, cabin class, and plenty of other options.

Why should you use Cheapflights to find cheap flight tickets from Southampton to Florida Keys?

Cheapflights taps into our reliable network of hundreds of airlines and travel agencies to find the best deals for flights from Southampton to Florida Keys for you. Better yet — we are completely free to use.

Can Cheapflights find flights from Southampton to Florida Keys with no change fees?

Need flexible booking options for your flight to Florida Keys from Southampton? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

Can Cheapflights notify me if prices for flights from Southampton to Florida Keys become cheaper?

Of course! You can now track prices for flights from Southampton to Florida Keys and get an alert from Cheapflights when they change. Have a valid email address ready and click the bell icon next to the flight deals above to set up your price alerts.

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