Cheap flights from Southampton to Florida Keys from £401

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 27/11. Fares are subject to change and may not be available on all flights or dates of travel.
SOU — EYW
14 Nov — 21 Nov1
1 adult
1 adult, Economy

Cheap flight deals from Southampton to Florida Keys

Keep the following information in mind while searching for Southampton to Florida Keys flight deals. Data was last updated 15 October 2025.

Round-trip from

£544

One-way from

£401

Popular in

December

Cheapest in

September

Average price

£529
Delta
  • Delta
  • 7/1-18/1
  • 2 total stops
  • 37h 20m total
  • Southampton to Florida Keys
27/11
  • 27/11
  • 3 total stops
  • 28h 10m total
  • Southampton to Florida Keys
Highest demand for flights based on searches. 2% potential increase in price (£11 potential increase over avg. return price).
Cheapest flight prices on average. 2% potential price decrease (£10 potential savings vs. average return price).
Average for round-trip flights in October 2025

Find flight deals from Southampton to Florida Keys

Enter your travel dates to find the best prices.

Cheapest flights from Southampton to Florida Keys
Explore the most affordable flight options available from Southampton to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 15 October 2025.

Sat 13/1217:30SOU - MIA
1 stop26h 20mDelta
Wed 24/1217:45MIA - SOU
2 stops33h 20mDelta
Deal found 14/10£554
Sat 13/1217:30SOU - MIA
1 stop26h 20mDelta
Mon 22/1210:21MIA - SOU
2 stops25h 39mDelta
Deal found 14/10£556
Thu 27/1118:05SOU - MIA
1 stop25h 45mVirgin Atlantic
Thu 4/1207:07MIA - SOU
2 stops19h 58mVirgin Atlantic
Deal found 13/10£569
Thu 27/1108:50SOU - MIA
2 stops20h 56mDelta
Thu 4/1207:00MIA - SOU
2 stops20h 05mDelta
Deal found 13/10£573
Sun 14/1209:30SOU - MIA
2 stops17h 44mDelta
Wed 24/1217:45MIA - SOU
2 stops33h 20mDelta
Deal found 14/10£575
Mon 8/1218:05SOU - MIA
1 stop25h 45mDelta
Thu 18/1215:50MIA - SOU
2 stops20h 10mDelta
Deal found 14/10£576
Thu 27/1108:50SOU - MIA
2 stops20h 56mKLM
Thu 4/1211:23MIA - SOU
2 stops15h 42mKLM
Deal found 13/10£579
Tue 23/1217:30SOU - MIA
2 stops29h 53mDelta
Thu 1/111:50MIA - SOU
2 stops15h 15mDelta
Deal found 14/10£590
Tue 9/1208:40SOU - MIA
2 stops17h 11mDelta
Thu 18/1215:50MIA - SOU
2 stops20h 10mDelta
Deal found 14/10£601
Tue 16/1208:40SOU - MIA
2 stops17h 11mDelta
Wed 24/1217:45MIA - SOU
2 stops33h 20mDelta
Deal found 14/10£608
Thu 11/1218:05SOU - MIA
1 stop25h 45mDelta
Mon 22/1210:21MIA - SOU
2 stops25h 39mDelta
Deal found 14/10£612
Thu 4/1218:05SOU - MIA
2 stops31h 46mDelta
Sat 13/1208:20MIA - SOU
2 stops19h 30mDelta
Deal found 14/10£614

Cheapflights Fare Finder

 
Customise your flight search to find flights from Southampton to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 15 October 2025.
Use the filters below to find and compare flights from Southampton to Florida Keys that are best for you.

Fly from

Southampton

Fly to

Florida Keys

Route

Depart

Return

Price

SouthamptonMiami

SOU - MIA

SOUMIA

Southampton Eastleigh

Wed 7/1

17:30-14:50

1 stop26h 20m

Miami

Sun 18/1

16:50-08:50

1 stop11h 00m

£544

SouthamptonMiami

SOU - MIA

SOUMIA

Southampton Eastleigh

Wed 7/1

17:30-14:50

1 stop26h 20m

Miami

Sat 17/1

12:01-17:15

2 stops24h 14m

£560

SouthamptonMiami

SOU - MIA

SOUMIA

Southampton Eastleigh

Sun 4/1

18:05-18:55

2 stops29h 50m

Miami

Tue 13/1

16:50-17:00

1 stop19h 10m

£564

SouthamptonMiami

SOU - MIA

SOUMIA

Southampton Eastleigh

Thu 27/11

18:05-14:50

1 stop25h 45m

Miami

Thu 4/12

07:07-08:05

2 stops19h 58m

£569

SouthamptonMiami

SOU - MIA

SOUMIA

Southampton Eastleigh

Thu 27/11

18:05-14:50

1 stop25h 45m

Miami

Thu 4/12

16:50-17:00

1 stop19h 10m

£569

SouthamptonMiami

SOU - MIA

SOUMIA

Southampton Eastleigh

Sun 14/12

09:30-22:14

2 stops17h 44m

Miami

Wed 24/12

17:45-08:05

2 stops33h 20m

£575

SouthamptonMiami

SOU - MIA

SOUMIA

Southampton Eastleigh

Mon 15/12

08:40-20:51

2 stops17h 11m

Miami

Thu 25/12

12:45-08:05

2 stops14h 20m

£575

SouthamptonMiami

SOU - MIA

SOUMIA

Southampton Eastleigh

Thu 27/11

08:50-00:46

2 stops20h 56m

Miami

Thu 4/12

11:23-08:05

2 stops15h 42m

£579

SouthamptonMiami

SOU - MIA

SOUMIA

Southampton Eastleigh

Fri 6/3

17:30-18:55

2 stops30h 25m

Miami

Tue 10/3

14:03-17:00

2 stops22h 57m

£581

SouthamptonMiami

SOU - MIA

SOUMIA

Southampton Eastleigh

Fri 6/3

17:30-16:44

2 stops28h 14m

Miami

Tue 10/3

17:50-17:00

1 stop19h 10m

£581

Flights are sorted by cheapest return flights first.

Deals found on 12/10

Showing 1-10 of 15 results
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Best time to book a flight from Southampton to Florida Keys

Have a flexible travel schedule? Discover the best time to fly to Florida Keys from Southampton with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Southampton to Florida Keys

What is the cheapest month to book a flight from Southampton to Florida Keys?

Currently, March is the cheapest month in which you can book a flight from Southampton to Florida Keys (average of £439). Flying from Southampton to Florida Keys in July is currently the most expensive (average of £645). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Southampton to Florida Keys. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Southampton to Florida Keys?

    For a flight from Southampton to Florida Keys, you will be flying from Eastleigh. Southampton Eastleigh (SOU) is just 3.5 mi from the center of the city.

  • How long is the flight from Southampton to Florida Keys?

    A quick flight from Southampton to Florida Keys can take about 25h 45m. Delta provides one of the quickest options available for as low as £569. Airlines will cover a distance of 4381 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Southampton to Florida Keys that include hotel bookings?

    Yes. In addition to deals on Southampton to Florida Keys flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Southampton to Florida Keys?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Southampton to Florida Keys.

  • Can I find deals for business class flights from Southampton to Florida Keys?

    Yes. Cheapflights offers flight deals from Southampton to Florida Keys by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Southampton to Florida Keys?

    Currently, March is the cheapest month in which you can book a flight from Southampton to Florida Keys (average of £439). Flying from Southampton to Florida Keys in July is currently the most expensive (average of £645). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Southampton to Florida Keys

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How does Cheapflights help users find flights from Southampton to Florida Keys?

Deals for Southampton to Florida Keys flights are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose better, like price, airport, cabin class, and plenty of other options.

Why should you use Cheapflights to find cheap flight tickets from Southampton to Florida Keys?

Cheapflights taps into our reliable network of hundreds of airlines and travel agencies to find the best deals for flights from Southampton to Florida Keys for you. Better yet — we are completely free to use.

Can Cheapflights find flights from Southampton to Florida Keys with no change fees?

Need flexible booking options for your flight to Florida Keys from Southampton? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

Can Cheapflights notify me if prices for flights from Southampton to Florida Keys become cheaper?

Of course! You can now track prices for flights from Southampton to Florida Keys and get an alert from Cheapflights when they change. Have a valid email address ready and click the bell icon next to the flight deals above to set up your price alerts.

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