Cheap flights from Southampton to Florida Keys from £452

This is the cheapest retur flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 15/12. Fares are subject to change and may not be available on all flights or dates of travel.
SOU — EYW
6 Sep — 13 Sep1
1 adult

Cheap flight deals from Southampton to Florida Keys

Keep the following information in mind while searching for Southampton to Florida Keys flight deals. Data was last updated 1 September 2025.

Round-trip from

£452

Popular in

December

Cheapest in

September

Average price

£403
15/12-15/2
  • 15/12-15/2
  • 4 total stops
  • 42h 15m total
  • Southampton to Florida Keys
Highest demand for flights based on searches. 2% potential increase in price (£7 potential increase over avg. return price).
Cheapest flight prices on average. 2% potential price decrease (£9 potential savings vs. average return price).
Average for round-trip flights in September 2025

Find flight deals from Southampton to Florida Keys

Cheapest flights from Southampton to Florida Keys
Explore the most affordable flight options available from Southampton to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 1 September 2025.

Mon 15/1219:55SOU - MIA
2 stops23h 45mMultiple Airlines
Sun 15/219:50MIA - SOU
2 stops18h 30mMultiple Airlines
Deal found 31/8£452
Sat 13/909:20SOU - MIA
2 stops18h 50mKLM
Tue 16/911:38MIA - SOU
2 stops16h 07mKLM
Deal found 30/8£505
Tue 14/1009:20SOU - MIA
2 stops18h 59mDelta
Tue 21/1018:15MIA - SOU
2 stops17h 45mDelta
Deal found 30/8£531
Mon 15/1218:05SOU - MIA
1 stop25h 45mKLM
Sun 15/216:50MIA - SOU
1 stop11h 00mKLM
Deal found 31/8£541
Thu 16/1009:20SOU - MIA
2 stops17h 07mDelta
Thu 23/1008:30MIA - SOU
2 stops19h 15mDelta
Deal found 1/9£561
Fri 10/1019:25SOU - MIA
1 stop28h 55mMultiple Airlines
Fri 17/1009:49MIA - SOU
2 stops17h 51mMultiple Airlines
Deal found 30/8£587
Tue 14/1009:10SOU - MIA
2 stops34h 35mMultiple Airlines
Tue 21/1009:49MIA - SOU
3 stops28h 41mMultiple Airlines
Deal found 30/8£615
Thu 16/1020:00SOU - MIA
2 stops30h 45mMultiple Airlines
Thu 23/1021:35MIA - SOU
1 stop16h 20mMultiple Airlines
Deal found 1/9£649

Cheapflights Fare Finder

 
Customise your flight search to find flights from Southampton to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 1 September 2025.
Use the filters below to find and compare flights from Southampton to Florida Keys that are best for you.

Fly from

Southampton

Fly to

Florida Keys

Route

Depart

Return

Price

SouthamptonMiami

SOU - MIA

SOUMIA

Southampton Eastleigh

Mon 15/12

19:55-14:40

2 stops23h 45m

Miami

Sun 15/2

19:50-19:20

2 stops18h 30m

£452

SouthamptonMiami

SOU - MIA

SOUMIA

Southampton Eastleigh

Sat 13/9

09:20-23:10

2 stops18h 50m

Miami

Tue 16/9

11:38-08:45

2 stops16h 07m

£505

SouthamptonMiami

SOU - MIA

SOUMIA

Southampton Eastleigh

Mon 9/2

17:30-14:50

1 stop26h 20m

Miami

Wed 18/2

19:35-17:00

2 stops16h 25m

£507

SouthamptonMiami

SOU - MIA

SOUMIA

Southampton Eastleigh

Wed 25/2

08:40-21:02

2 stops17h 22m

Miami

Thu 5/3

11:35-08:05

2 stops15h 30m

£511

SouthamptonMiami

SOU - MIA

SOUMIA

Southampton Eastleigh

Tue 10/2

17:30-16:44

2 stops28h 14m

Miami

Wed 18/2

16:40-17:00

2 stops19h 20m

£511

SouthamptonMiami

SOU - MIA

SOUMIA

Southampton Eastleigh

Wed 11/2

09:25-21:02

2 stops16h 37m

Miami

Wed 18/2

17:55-17:00

2 stops18h 05m

£511

SouthamptonMiami

SOU - MIA

SOUMIA

Southampton Eastleigh

Sun 8/2

17:45-18:57

2 stops30h 12m

Miami

Wed 18/2

19:35-17:00

2 stops16h 25m

£511

SouthamptonMiami

SOU - MIA

SOUMIA

Southampton Eastleigh

Tue 14/10

09:20-23:19

2 stops18h 59m

Miami

Tue 21/10

18:15-17:00

2 stops17h 45m

£531

SouthamptonMiami

SOU - MIA

SOUMIA

Southampton Eastleigh

Thu 26/2

08:50-23:20

2 stops19h 30m

Miami

Thu 5/3

11:35-08:05

2 stops15h 30m

£540

SouthamptonMiami

SOU - MIA

SOUMIA

Southampton Eastleigh

Wed 25/2

08:40-22:50

2 stops19h 10m

Miami

Fri 6/3

16:50-08:50

1 stop11h 00m

£540

Flights are sorted by cheapest return flights first.

Deals found on 1/9

Showing 1-10 of 19 results
1
2

Best time to book a flight from Southampton to Florida Keys

Have a flexible travel schedule? Discover the best time to fly to Florida Keys from Southampton with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Southampton to Florida Keys
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Florida Keys

Get insights into the airlines that provide service to Florida Keys. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florida Keys. Reviews last updated 1 September 2025.
Check out reviews from past customers who have flown with KLM from Southampton to Florida Keys to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Boarding

7.8

Entertainment

7.1

Overall

7.8

Comfort

7.7

Food

7.3

Crew

8.4

Reviews

1 / 20
4.0
Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.

Boarding

7.8

Entertainment

7.1

Overall

7.8

Comfort

7.7

Food

7.3

Crew

8.4

Reviews

1 / 20
4.0
Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.

Related info for your journey

Find useful and relevant information for your journey from Southampton to Florida Keys. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Southampton to Florida Keys?

    For a flight from Southampton to Florida Keys, you will be flying from Eastleigh. Southampton Eastleigh (SOU) is just 3.5 mi from the center of the city.

  • How long is the flight from Southampton to Florida Keys?

    A quick flight from Southampton to Florida Keys can take about 18h 50m. KLM provides one of the quickest options available for as low as £505. Airlines will cover a distance of 4381 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Southampton to Florida Keys that include hotel bookings?

    Yes. In addition to deals on Southampton to Florida Keys flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Southampton to Florida Keys?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Southampton to Florida Keys.

  • Can I find deals for business class flights from Southampton to Florida Keys?

    Yes. Cheapflights offers flight deals from Southampton to Florida Keys by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Southampton to Florida Keys

See prices for flight routes from nearby airports that may be better suited for you.

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Deals for Southampton to Florida Keys flights are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose better, like price, airport, cabin class, and plenty of other options.

Why should you use Cheapflights to find cheap flight tickets from Southampton to Florida Keys?

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Can Cheapflights find flights from Southampton to Florida Keys with no change fees?

Need flexible booking options for your flight to Florida Keys from Southampton? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

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