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Cheap flights from Panama City to Guatemala City from £109

PTY — GUA
3 Oct — 10 Oct1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Panama City to Guatemala City

Enter your travel dates to find the best prices.

Cheapest flights from Panama City to Guatemala City

Wed 4/1118:34 -
1 stop4h 02m
Sat 7/1102:22 -
Nonstop2h 27m
Deal found 31/8£203
Thu 5/1107:25 -
Nonstop2h 21m
Sat 7/1106:24 -
1 stop12h 56m
Deal found 3/9£209
Thu 12/1108:15 -
Nonstop2h 24m
Tue 17/1116:17 -
Nonstop2h 34m
Deal found 3/9£210
Wed 11/1108:15 -
Nonstop2h 24m
Mon 30/1106:24 -
1 stop12h 56m
Deal found 2/9£217
Sat 14/1118:10 -
1 stop7h 45m
Thu 19/1105:25 -
1 stop4h 10m
Deal found 31/8£218
Wed 23/918:35 -
1 stop4h 01m
Fri 23/1006:24 -
1 stop3h 46m
Deal found 3/9£219
Mon 28/1205:30 -
1 stop8h 05m
Thu 21/102:00 -
1 stop12h 15m
Deal found 31/8£219
Sat 14/1115:55 -
1 stop8h 10m
Fri 20/1120:15 -
1 stop4h 55m
Deal found 1/9£222
Fri 6/1110:25 -
Nonstop2h 25m
Mon 9/1106:24 -
1 stop5h 04m
Deal found 30/8£222
Thu 24/918:35 -
1 stop4h 01m
Fri 25/904:20 -
Nonstop2h 30m
Deal found 3/9£225
Wed 28/1007:24 -
Nonstop2h 22m
Wed 4/1107:16 -
Nonstop2h 31m
Deal found 3/9£227
Wed 18/1108:15 -
Nonstop2h 24m
Mon 23/1106:24 -
1 stop5h 04m
Deal found 2/9£230

Find flight deals from Panama City to Guatemala City

Round-trip from

£203

One-way from

£109

Popular in

January

Cheapest in

March

Average price

£219
Copa Airlines
  • Copa Airlines
  • 5/11-7/11
  • Nonstop
  • 4h 48m total
  • Panama City to Guatemala City
Search Deals
Copa Airlines
  • Copa Airlines
  • 4/11-31/12
  • Nonstop
  • 2h 25m total
  • Panama City to Guatemala City
Search Deals
Highest demand for flights based on searches. 2% potential increase in price (£3 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 0% potential price decrease (£1 potential savings vs. average return price).
Search Deals
Average for round-trip flights in September 2026
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Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Panama City to Guatemala City that are best for you.

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Route

Depart

Return

Price

Cheapest return flight

Panama CityGuatemala City

PTY Panama City Tocumen Intl - GUA Guatemala City La Aurora

PTYGUA

Panama City Tocumen Intl

Tue 2/2

18:34-21:36

1 stop4h 02m

Guatemala City La Aurora

Wed 31/12

00:00-01:00

Nonstop0h 00m

£117

Panama CityGuatemala City

PTY Panama City Tocumen Intl - GUA Guatemala City La Aurora

PTYGUA

Panama City Tocumen Intl

Tue 6/10

18:35-21:36

1 stop4h 01m

Guatemala City La Aurora

Wed 31/12

00:00-01:00

Nonstop0h 00m

£117

Panama CityGuatemala City

PTY Panama City Tocumen Intl - GUA Guatemala City La Aurora

PTYGUA

Panama City Tocumen Intl

Mon 12/10

18:35-21:36

1 stop4h 01m

Guatemala City La Aurora

Wed 31/12

00:00-01:00

Nonstop0h 00m

£117

Panama CityGuatemala City

PTY Panama City Tocumen Intl - GUA Guatemala City La Aurora

PTYGUA

Panama City Tocumen Intl

Sat 28/11

10:25-11:50

Nonstop2h 25m

Guatemala City La Aurora

Wed 31/12

00:00-01:00

Nonstop0h 00m

£117

Panama CityGuatemala City

PTY Panama City Tocumen Intl - GUA Guatemala City La Aurora

PTYGUA

Panama City Tocumen Intl

Tue 13/10

18:35-21:36

1 stop4h 01m

Guatemala City La Aurora

Wed 31/12

00:00-01:00

Nonstop0h 00m

£117

Panama CityGuatemala City

PTY Panama City Tocumen Intl - GUA Guatemala City La Aurora

PTYGUA

Panama City Tocumen Intl

Mon 1/2

21:45-23:09

Nonstop2h 24m

Guatemala City La Aurora

Wed 31/12

00:00-01:00

Nonstop0h 00m

£117
Fastest return journey

Panama CityGuatemala City

PTY Panama City Tocumen Intl - GUA Guatemala City La Aurora

PTYGUA

Panama City Tocumen Intl

Tue 27/10

07:24-08:46

Nonstop2h 22m

Guatemala City La Aurora

Wed 31/12

00:00-01:00

Nonstop0h 00m

£117

Panama CityGuatemala City

PTY Panama City Tocumen Intl - GUA Guatemala City La Aurora

PTYGUA

Panama City Tocumen Intl

Tue 22/9

18:35-21:36

1 stop4h 01m

Guatemala City La Aurora

Wed 31/12

00:00-01:00

Nonstop0h 00m

£117

Panama CityGuatemala City

PTY Panama City Tocumen Intl - GUA Guatemala City La Aurora

PTYGUA

Panama City Tocumen Intl

Mon 28/9

08:11-09:33

Nonstop2h 22m

Guatemala City La Aurora

Wed 31/12

00:00-01:00

Nonstop0h 00m

£117

Panama CityGuatemala City

PTY Panama City Tocumen Intl - GUA Guatemala City La Aurora

PTYGUA

Panama City Tocumen Intl

Tue 17/11

13:28-21:36

1 stop9h 08m

Guatemala City La Aurora

Wed 31/12

00:00-01:00

Nonstop0h 00m

£130

Flights are sorted by cheapest return flights first.

Deals found on 1/9

Showing 1-10 of 19 resultsSorted by cheapest first
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Best time to book a flight from Panama City to Guatemala City

Have a flexible travel schedule? Discover the best time to fly to Guatemala City from Panama City with our price prediction graph.
Estimated return price

Cheapflights Insights

Everything you need to know about your flight from Panama City to Guatemala City

How far ahead should I book a flight from Panama City to Guatemala City?

Booking 54 days in advance of your planned departure date is, on average, the best time to get cheap flights from Panama City to Guatemala City. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Panama City to Guatemala City?

Currently, March is the cheapest month in which you can book a flight from Panama City to Guatemala City (average of £206). Flying from Panama City to Guatemala City in January is currently the most expensive (average of £231). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to GUA?

When flying from Panama City to Guatemala City, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

How much does it cost for a return flight from Panama City to Guatemala City?

Airfare is typical for this route at the moment.

Panama City to Guatemala City flights typically cost between £190 and £239 in November.
The cheapest return price found within the last 5 days was £203 on Copa Airlines (4 Nov–7 Nov).

Related info for your journey

  • How long is the flight from Panama City to Guatemala City?

    Airlines like Copa Airlines fly from Panama City to Guatemala City in about 2h 25m. The time it takes to get you to your destination is usually consistent. Panama City and Guatemala City are separated by a distance of 843 mi. All flights are typically direct.

  • What are the most reliable airlines from Panama City to Guatemala City?

    Consider KLM (92%), Iberia (91%) or Copa Airlines (91%) when booking your flight. These represent the most reliable airlines when flying from Panama City to Guatemala City.

  • Can I find deals for flights from Panama City to Guatemala City that include hotel bookings?

    Yes. In addition to deals on Panama City to Guatemala City flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Guatemala City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Guatemala City.

  • Can I find deals for business class flights from Panama City to Guatemala City?

    Yes. Cheapflights offers flight deals from Panama City to Guatemala City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Guatemala City?

    Currently, March is the cheapest month in which you can book a flight from Panama City to Guatemala City (average of £206). Flying from Panama City to Guatemala City in January is currently the most expensive (average of £231). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Guatemala City La Aurora Airport car hire

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Certainly. Search results for flights to Guatemala City from Panama City shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

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