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Cheap flights from Panama City to Guatemala City from £111

PTY — GUA
2 Nov — 9 Nov1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Panama City to Guatemala City

Enter your travel dates to find the best prices.

Cheapest flights from Panama City to Guatemala City

Sun 1/1107:25 -
Nonstop2h 21m
Thu 5/1102:22 -
Nonstop2h 27m
Deal found 28/9£201
Mon 2/1108:15 -
Nonstop2h 24m
Thu 5/1106:19 -
1 stop9h 25m
Deal found 28/9£207
Tue 10/1121:45 -
Nonstop2h 21m
Wed 18/1106:19 -
1 stop13h 16m
Deal found 29/9£213
Wed 4/1118:30 -
Nonstop2h 21m
Sat 7/1104:16 -
Nonstop2h 28m
Deal found 2/10£215
Wed 11/1102:30 -
1 stop11h 35m
Thu 12/1115:40 -
1 stop9h 30m
Deal found 2/10£216
Sun 18/1010:25 -
Nonstop2h 22m
Sat 24/1012:57 -
Nonstop2h 30m
Deal found 29/9£223
Thu 12/1102:30 -
1 stop15h 55m
Fri 20/1109:20 -
1 stop15h 00m
Deal found 29/9£224
Thu 29/1007:24 -
Nonstop2h 22m
Tue 10/1106:19 -
1 stop13h 16m
Deal found 30/9£225
Tue 3/1107:25 -
Nonstop2h 21m
Wed 11/1106:19 -
1 stop13h 16m
Deal found 28/9£227
Fri 4/1207:25 -
Nonstop2h 21m
Wed 9/1206:24 -
1 stop3h 45m
Deal found 29/9£229

Find flight deals from Panama City to Guatemala City

Round-trip from

£201

One-way from

£111

Popular in

April

Cheapest in

March

Average price

£223
Copa Airlines
  • Copa Airlines
  • 1/11-5/11
  • Nonstop
  • 4h 48m total
  • Panama City to Guatemala City
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Copa Airlines
  • Copa Airlines
  • 7/11-31/12
  • Nonstop
  • 2h 25m total
  • Panama City to Guatemala City
Search Deals
High demand for flights, 0% potential price rise
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Cheapest flight prices on average. 0% potential price decrease (£1 potential savings vs. average return price).
Search Deals
Average for round-trip flights in October 2026
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Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Panama City to Guatemala City that are best for you.

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Route

Depart

Return

Price

Cheapest return flight
Fastest return journey

Panama CityGuatemala City

PTY Panama City Tocumen Intl - GUA Guatemala City La Aurora

PTYGUA

Panama City Tocumen Intl

Thu 12/11

21:45-23:06

Nonstop2h 21m

Guatemala City La Aurora

Wed 31/12

00:00-01:00

Nonstop0h 00m

£111

Panama CityGuatemala City

PTY Panama City Tocumen Intl - GUA Guatemala City La Aurora

PTYGUA

Panama City Tocumen Intl

Wed 4/11

18:30-19:51

Nonstop2h 21m

Guatemala City La Aurora

Wed 31/12

00:00-01:00

Nonstop0h 00m

£120

Panama CityGuatemala City

PTY Panama City Tocumen Intl - GUA Guatemala City La Aurora

PTYGUA

Panama City Tocumen Intl

Wed 11/11

02:30-13:05

1 stop11h 35m

Guatemala City La Aurora

Thu 12/11

15:40-02:10

1 stop9h 30m

£216

Panama CityGuatemala City

PTY Panama City Tocumen Intl - GUA Guatemala City La Aurora

PTYGUA

Panama City Tocumen Intl

Mon 1/2

18:34-21:36

1 stop4h 02m

Guatemala City La Aurora

Sun 14/2

04:18-07:44

Nonstop2h 26m

£223

Panama CityGuatemala City

PTY Panama City Tocumen Intl - GUA Guatemala City La Aurora

PTYGUA

Panama City Tocumen Intl

Sat 13/2

07:25-08:48

Nonstop2h 23m

Guatemala City La Aurora

Fri 19/2

04:18-07:44

Nonstop2h 26m

£223

Panama CityGuatemala City

PTY Panama City Tocumen Intl - GUA Guatemala City La Aurora

PTYGUA

Panama City Tocumen Intl

Wed 2/12

21:45-23:08

Nonstop2h 23m

Guatemala City La Aurora

Wed 9/12

06:24-11:09

1 stop3h 45m

£223

Panama CityGuatemala City

PTY Panama City Tocumen Intl - GUA Guatemala City La Aurora

PTYGUA

Panama City Tocumen Intl

Thu 18/3

06:13-07:35

Nonstop2h 22m

Guatemala City La Aurora

Sun 21/3

01:37-05:00

Nonstop2h 23m

£223

Panama CityGuatemala City

PTY Panama City Tocumen Intl - GUA Guatemala City La Aurora

PTYGUA

Panama City Tocumen Intl

Wed 20/1

08:15-09:38

Nonstop2h 23m

Guatemala City La Aurora

Sat 23/1

16:21-19:51

Nonstop2h 30m

£223

Panama CityGuatemala City

PTY Panama City Tocumen Intl - GUA Guatemala City La Aurora

PTYGUA

Panama City Tocumen Intl

Sat 6/2

21:45-23:09

Nonstop2h 24m

Guatemala City La Aurora

Tue 9/2

04:18-07:44

Nonstop2h 26m

£223

Panama CityGuatemala City

PTY Panama City Tocumen Intl - GUA Guatemala City La Aurora

PTYGUA

Panama City Tocumen Intl

Mon 21/12

07:25-08:46

Nonstop2h 21m

Guatemala City La Aurora

Wed 31/12

00:00-01:00

Nonstop0h 00m

£254

Flights are sorted by cheapest return flights first.

Deals found on 30/9

Showing 1-10 of 17 resultsSorted by cheapest first
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Best time to book a flight from Panama City to Guatemala City

Have a flexible travel schedule? Discover the best time to fly to Guatemala City from Panama City with our price prediction graph.
Estimated return price

Cheapflights Insights

Everything you need to know about your flight from Panama City to Guatemala City

How far ahead should I book a flight from Panama City to Guatemala City?

Booking 82 days in advance of your planned departure date is, on average, the best time to get cheap flights from Panama City to Guatemala City. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Panama City to Guatemala City?

Currently, March is the cheapest month in which you can book a flight from Panama City to Guatemala City (average of £209). Flying from Panama City to Guatemala City in April is currently the most expensive (average of £236). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to GUA?

When flying from Panama City to Guatemala City, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

How much does it cost for a return flight from Panama City to Guatemala City?

Airfare is below average for this route at the moment.

Panama City to Guatemala City flights typically cost between £216 and £252 in November.
The cheapest return price found within the last 5 days was £201 on Copa Airlines (1 Nov–5 Nov).

Related info for your journey

  • How long is the flight from Panama City to Guatemala City?

    Airlines like Copa Airlines fly from Panama City to Guatemala City in about 2h 21m. The time it takes to get you to your destination is usually consistent. Panama City and Guatemala City are separated by a distance of 843 mi. All flights are typically direct.

  • What are the most reliable airlines from Panama City to Guatemala City?

    Consider Iberia (92%), Copa Airlines (92%) or Air Europa (90%) when booking your flight. These represent the most reliable airlines when flying from Panama City to Guatemala City.

  • Can I find deals for flights from Panama City to Guatemala City that include hotel bookings?

    Yes. In addition to deals on Panama City to Guatemala City flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Guatemala City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Guatemala City.

  • Can I find deals for business class flights from Panama City to Guatemala City?

    Yes. Cheapflights offers flight deals from Panama City to Guatemala City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Guatemala City?

    Currently, March is the cheapest month in which you can book a flight from Panama City to Guatemala City (average of £209). Flying from Panama City to Guatemala City in April is currently the most expensive (average of £236). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Certainly. Search results for flights to Guatemala City from Panama City shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

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