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Cheap flights from Madrid, Spain to Guayaquil from £352

MAD — GYE
7 Oct — 14 Oct1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Madrid to Guayaquil

Enter your travel dates to find the best prices.

Cheapest flights from Madrid to Guayaquil

Thu 12/1112:50 -
Nonstop11h 55m
Mon 19/408:48 -
2 stops25h 32m
Deal found 6/9£701
Thu 22/1001:40 -
Nonstop11h 30m
Fri 6/1112:05 -
Nonstop10h 45m
Deal found 5/9£711
Thu 26/1101:45 -
Nonstop11h 35m
Wed 9/1212:05 -
Nonstop10h 45m
Deal found 3/9£725
Mon 9/1115:50 -
2 stops28h 44m
Mon 19/406:05 -
2 stops19h 40m
Deal found 6/9£726
Tue 8/915:05 -
1 stop15h 56m
Wed 18/1112:05 -
Nonstop10h 45m
Deal found 3/9£738
Sun 18/1001:40 -
Nonstop11h 30m
Mon 26/1012:05 -
Nonstop10h 45m
Deal found 6/9£747
Sat 31/1001:45 -
Nonstop11h 35m
Mon 30/1112:05 -
Nonstop10h 45m
Deal found 2/9£755
Sat 31/1001:45 -
Nonstop11h 35m
Fri 27/1112:05 -
Nonstop10h 45m
Deal found 7/9£755
Tue 1/1201:45 -
Nonstop11h 35m
Wed 9/1212:05 -
Nonstop10h 45m
Deal found 3/9£760

Find flight deals from Madrid to Guayaquil

Round-trip from

£698

One-way from

£352

Popular in

August

Cheapest in

February

Average price

£774
Air Europa
  • Air Europa
  • 2/2-17/2
  • Nonstop
  • 22h 20m total
  • Madrid to Guayaquil
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Air Europa
  • Air Europa
  • 22/9-31/12
  • Nonstop
  • 11h 30m total
  • Madrid to Guayaquil
Search Deals
Highest demand for flights based on searches. 15% potential increase in price (£107 potential increase over avg. return price).
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Cheapest flight prices on average. 3% potential price decrease (£18 potential savings vs. average return price).
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Average for round-trip flights in September 2026
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Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Madrid to Guayaquil that are best for you.

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Route

Depart

Return

Price

Cheapest return flight

MadridGuayaquil

MAD Madrid Barajas - GYE Guayaquil Jose Joaquin de Olmedo

MADGYE

Madrid Barajas

Sat 19/9

10:50-17:30

2 stops37h 40m

Guayaquil Jose Joaquin de Olmedo

Wed 31/12

00:00-06:00

Nonstop0h 00m

£424

MadridGuayaquil

MAD Madrid Barajas - GYE Guayaquil Jose Joaquin de Olmedo

MADGYE

Madrid Barajas

Fri 18/9

10:50-23:37

2 stops19h 47m

Guayaquil Jose Joaquin de Olmedo

Wed 31/12

00:00-06:00

Nonstop0h 00m

£424

MadridGuayaquil

MAD Madrid Barajas - GYE Guayaquil Jose Joaquin de Olmedo

MADGYE

Madrid Barajas

Wed 23/9

10:50-20:52

2 stops41h 02m

Guayaquil Jose Joaquin de Olmedo

Wed 31/12

00:00-06:00

Nonstop0h 00m

£424

MadridGuayaquil

MAD Madrid Barajas - GYE Guayaquil Jose Joaquin de Olmedo

MADGYE

Madrid Barajas

Thu 22/10

10:50-20:52

2 stops41h 02m

Guayaquil Jose Joaquin de Olmedo

Wed 31/12

00:00-06:00

Nonstop0h 00m

£424

MadridGuayaquil

MAD Madrid Barajas - GYE Guayaquil Jose Joaquin de Olmedo

MADGYE

Madrid Barajas

Tue 15/9

10:50-17:30

2 stops37h 40m

Guayaquil Jose Joaquin de Olmedo

Wed 31/12

00:00-06:00

Nonstop0h 00m

£425
Fastest return journey

MadridGuayaquil

MAD Madrid Barajas - GYE Guayaquil Jose Joaquin de Olmedo

MADGYE

Madrid Barajas

Fri 11/9

01:40-06:10

Nonstop11h 30m

Guayaquil Jose Joaquin de Olmedo

Wed 31/12

00:00-06:00

Nonstop0h 00m

£450

MadridGuayaquil

MAD Madrid Barajas - GYE Guayaquil Jose Joaquin de Olmedo

MADGYE

Madrid Barajas

Thu 1/10

01:40-06:10

Nonstop11h 30m

Guayaquil Jose Joaquin de Olmedo

Wed 31/12

00:00-06:00

Nonstop0h 00m

£516

MadridGuayaquil

MAD Madrid Barajas - GYE Guayaquil Jose Joaquin de Olmedo

MADGYE

Madrid Barajas

Fri 25/9

15:05-00:01

1 stop15h 56m

Guayaquil Jose Joaquin de Olmedo

Wed 31/12

00:00-06:00

Nonstop0h 00m

£523

MadridGuayaquil

MAD Madrid Barajas - GYE Guayaquil Jose Joaquin de Olmedo

MADGYE

Madrid Barajas

Thu 8/10

15:05-11:21

1 stop27h 16m

Guayaquil Jose Joaquin de Olmedo

Wed 31/12

00:00-06:00

Nonstop0h 00m

£627

MadridGuayaquil

MAD Madrid Barajas - GYE Guayaquil Jose Joaquin de Olmedo

MADGYE

Madrid Barajas

Wed 14/10

15:05-23:37

1 stop15h 32m

Guayaquil Jose Joaquin de Olmedo

Wed 31/12

00:00-06:00

Nonstop0h 00m

£627

Flights are sorted by cheapest return flights first.

Deals found on 2/9

Showing 1-10 of 23 resultsSorted by cheapest first
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Best time to book a flight from Madrid to Guayaquil

Have a flexible travel schedule? Discover the best time to fly to Guayaquil from Madrid with our price prediction graph.
Estimated return price

Cheapflights Insights

Everything you need to know about your flight from Madrid to Guayaquil

How far ahead should I book a flight from Madrid to Guayaquil?

To ensure you get the cheapest price possible for a flight from Madrid to Guayaquil, you should look to book at least 84 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Madrid to Guayaquil?

Currently, February is the cheapest month in which you can book a flight from Madrid to Guayaquil (average of £668). Flying from Madrid to Guayaquil in August is currently the most expensive (average of £1,069). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MAD to GYE?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Madrid to Guayaquil as you normally would.

How much does it cost for a return flight from Madrid to Guayaquil?

Airfare is below average for this route at the moment.

Madrid to Guayaquil flights typically cost between £718 and £883 in February.
The cheapest return price found within the last 5 days was £698 on Air Europa (2 Feb–17 Feb).

Related info for your journey

  • How popular is this Madrid to Guayaquil flight route?

    The Madrid Barajas to Guayaquil Jose Joaquin de Olmedo flight path was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Madrid to Guayaquil?

    Air Europa and United Airlines can get you from Madrid to Guayaquil in just under 11h 30m. Your travel time can differ by up to 28h 26m. The distance from Madrid to Guayaquil is about 5597 mi. This flight may include one or multiple stops.

  • What are the most reliable airlines from Madrid to Guayaquil?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Madrid to Guayaquil on time: Air Europa (94%), Qatar Airways (84%), LATAM Airlines (84%).

  • Can I find deals for flights from Madrid to Guayaquil that include hotel bookings?

    Yes. In addition to deals on Madrid to Guayaquil flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Madrid to Guayaquil?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Madrid to Guayaquil.

  • Can I find deals for business class flights from Madrid to Guayaquil?

    Yes. Cheapflights offers flight deals from Madrid to Guayaquil by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Madrid to Guayaquil?

    Currently, February is the cheapest month in which you can book a flight from Madrid to Guayaquil (average of £668). Flying from Madrid to Guayaquil in August is currently the most expensive (average of £1,069). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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