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Cheap flights from Santiago to Manchester from £450

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 29/5. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — MAN
6 Apr — 13 Apr1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Santiago to Manchester

Enter your travel dates to find the best prices.

Cheapest flights from Santiago to Manchester
Explore the most affordable flight options available from Santiago to Manchester. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 7 March 2026.

Wed 11/312:05
SCL
-
MAN
1 stop19h 05m
Air France
Mon 6/410:55
MAN
-
SCL
1 stop25h 55m
Air France
Deal found 2/3£720
Wed 11/312:05
SCL
-
MAN
2 stops19h 05m
Multiple Airlines
Mon 6/417:50
MAN
-
SCL
1 stop19h 00m
Multiple Airlines
Deal found 2/3£743
Sun 15/312:05
SCL
-
MAN
1 stop30h 25m
Air France
Tue 7/414:55
MAN
-
SCL
1 stop21h 55m
Air France
Deal found 5/3£744
Sun 15/312:05
SCL
-
MAN
2 stops19h 05m
Multiple Airlines
Tue 7/414:55
MAN
-
SCL
1 stop21h 55m
Multiple Airlines
Deal found 5/3£747
Tue 24/312:05
SCL
-
MAN
1 stop19h 05m
Air France
Tue 31/314:55
MAN
-
SCL
1 stop21h 55m
Air France
Deal found 5/3£752
Tue 3/313:05
SCL
-
MAN
1 stop25h 35m
Iberia
Tue 14/409:30
MAN
-
SCL
1 stop26h 55m
Iberia
Deal found 2/3£757
Tue 10/312:05
SCL
-
MAN
2 stops19h 05m
Multiple Airlines
Tue 7/410:55
MAN
-
SCL
1 stop25h 55m
Multiple Airlines
Deal found 2/3£760
Tue 10/312:05
SCL
-
MAN
1 stop27h 35m
Air France
Tue 7/414:55
MAN
-
SCL
1 stop21h 55m
Air France
Deal found 2/3£785
Tue 3/313:05
SCL
-
MAN
1 stop25h 35m
Multiple Airlines
Tue 14/416:05
MAN
-
SCL
2 stops20h 20m
Multiple Airlines
Deal found 2/3£795

Find flight deals from Santiago to Manchester

Discover tips and strategies to find the most affordable flight options for your journey from Santiago (SCL) to Manchester (MAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 7 March 2026.

Round-trip from

£752

One-way from

£450

Popular in

January

Cheapest in

February

Average price

£976
Air France
  • Air France
  • 24/3-31/3
  • 2 total stops
  • 41h 00m total
  • Santiago to Manchester
Search Deals
29/5
  • 29/5
  • 3 total stops
  • 59h 00m total
  • Santiago to Manchester
Search Deals
Highest demand for flights based on searches. 4% potential increase in price (£38 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease (£27 potential savings vs. average return price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Santiago to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 7 March 2026.
Use the filters below to find and compare flights from Santiago to Manchester that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

SantiagoManchester

SCL - MAN

SCLMAN

Santiago Arturo Merino Benitez

Tue 24/3

12:05-10:10

2 stops19h 05m

Manchester

Tue 31/3

14:55-08:50

1 stop21h 55m

£934

SantiagoManchester

SCL - MAN

SCLMAN

Santiago Arturo Merino Benitez

Tue 30/6

16:00-00:45

1 stop27h 45m

Manchester

Thu 30/7

20:25-08:30

2 stops65h 05m

£1,135

SantiagoManchester

SCL - MAN

SCLMAN

Santiago Arturo Merino Benitez

Thu 25/6

10:30-12:40

1 stop21h 10m

Manchester

Fri 3/7

09:40-08:35

1 stop27h 55m

£1,141

SantiagoManchester

SCL - MAN

SCLMAN

Santiago Arturo Merino Benitez

Mon 18/5

10:15-16:45

2 stops25h 30m

Manchester

Tue 21/7

17:45-07:50

1 stop19h 05m

£1,245

SantiagoManchester

SCL - MAN

SCLMAN

Santiago Arturo Merino Benitez

Tue 30/6

15:00-15:10

1 stop19h 10m

Manchester

Thu 30/7

13:55-07:25

1 stop22h 30m

£1,258

SantiagoManchester

SCL - MAN

SCLMAN

Santiago Arturo Merino Benitez

Sat 25/4

10:10-10:10

2 stops19h 00m

Manchester

Sat 2/5

13:45-07:50

2 stops23h 05m

£1,258

SantiagoManchester

SCL - MAN

SCLMAN

Santiago Arturo Merino Benitez

Mon 18/5

10:40-08:50

1 stop17h 10m

Manchester

Tue 21/7

16:05-20:40

2 stops33h 35m

£1,367

SantiagoManchester

SCL - MAN

SCLMAN

Santiago Arturo Merino Benitez

Mon 6/7

10:10-13:10

2 stops22h 00m

Manchester

Fri 31/7

17:50-07:50

1 stop19h 00m

£1,453

SantiagoManchester

SCL - MAN

SCLMAN

Santiago Arturo Merino Benitez

Mon 6/7

10:10-13:10

2 stops22h 00m

Manchester

Fri 31/7

17:30-08:45

2 stops20h 15m

£1,465
Fastest return journey

SantiagoManchester

SCL - MAN

SCLMAN

Santiago Arturo Merino Benitez

Fri 10/4

10:40-08:50

1 stop17h 10m

Manchester

Thu 28/5

14:00-07:25

2 stops22h 25m

£1,539

Flights are sorted by cheapest return flights first.

Deals found on 6/3

Showing 1-10 of 17 resultsSorted by cheapest first
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Best time to book a flight from Santiago to Manchester

Have a flexible travel schedule? Discover the best time to fly to Manchester from Santiago with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santiago to Manchester

What is the cheapest month to book a flight from Santiago to Manchester?

Currently, February is the cheapest month in which you can book a flight from Santiago to Manchester (average of £553). Flying from Santiago to Manchester in April is currently the most expensive (average of £972). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Santiago to Manchester. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santiago to Manchester?

    A quick flight from Santiago to Manchester can take about 19h 10m. British Airways provides one of the quickest options available for as low as £1,258. The distance between Santiago and Manchester is about 7251 mi.

  • Can I find deals for flights from Santiago to Manchester that include hotel bookings?

    Yes. In addition to deals on Santiago to Manchester flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Santiago to Manchester?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to Manchester.

  • Can I find deals for business class flights from Santiago to Manchester?

    Yes. Cheapflights offers flight deals from Santiago to Manchester by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santiago to Manchester?

    Currently, February is the cheapest month in which you can book a flight from Santiago to Manchester (average of £553). Flying from Santiago to Manchester in April is currently the most expensive (average of £972). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Manchester?

Book flights to Manchester if you plan to visit one of these locations
Windermere
Llandudno
Lincoln
Bradford
Derby
Harrogate
Stoke-on-Trent
Southport
Otley
Telford
Salford
Warrington
Lancaster
Bolton
Preston
Wakefield
Huddersfield
Macclesfield
Rochdale
Stockport

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Can Cheapflights find flights from Santiago to Manchester with no change fees?

Need flexible booking options for your flight to Manchester from Santiago? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

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Of course! You can now track prices for flights from Santiago to Manchester and get an alert from Cheapflights when they change. Have a valid email address ready and click the bell icon next to the flight deals above to set up your price alerts.

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