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Cheap flights from Santiago to Manchester from £410

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 20/3. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — MAN
15 Mar — 22 Mar1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Santiago to Manchester

Enter your travel dates to find the best prices.

Cheapest flights from Santiago to Manchester
Explore the most affordable flight options available from Santiago to Manchester. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 13 February 2026.

Tue 17/313:05
SCL
-
MAN
1 stop23h 20m
Multiple Airlines
Wed 15/406:35
MAN
-
SCL
1 stop18h 15m
Multiple Airlines
Deal found 11/2£661
Wed 11/322:45
SCL
-
MAN
1 stop19h 30m
Multiple Airlines
Wed 8/406:35
MAN
-
SCL
1 stop18h 15m
Multiple Airlines
Deal found 11/2£668
Sun 15/323:55
SCL
-
MAN
1 stop18h 45m
Multiple Airlines
Wed 15/406:35
MAN
-
SCL
1 stop18h 15m
Multiple Airlines
Deal found 11/2£668
Sun 15/323:55
SCL
-
MAN
1 stop18h 45m
Multiple Airlines
Wed 8/406:35
MAN
-
SCL
1 stop18h 15m
Multiple Airlines
Deal found 11/2£669
Sun 15/323:55
SCL
-
MAN
1 stop18h 45m
Multiple Airlines
Tue 14/413:35
MAN
-
SCL
1 stop22h 50m
Multiple Airlines
Deal found 11/2£671
Wed 18/313:05
SCL
-
MAN
1 stop22h 20m
Multiple Airlines
Sat 11/413:10
MAN
-
SCL
1 stop23h 15m
Multiple Airlines
Deal found 11/2£671
Wed 18/313:05
SCL
-
MAN
1 stop22h 20m
Multiple Airlines
Tue 7/413:35
MAN
-
SCL
1 stop22h 50m
Multiple Airlines
Deal found 9/2£676
Wed 18/313:05
SCL
-
MAN
1 stop22h 20m
Multiple Airlines
Wed 8/406:35
MAN
-
SCL
1 stop18h 15m
Multiple Airlines
Deal found 11/2£678
Mon 16/312:25
SCL
-
MAN
2 stops24h 00m
Multiple Airlines
Tue 14/413:35
MAN
-
SCL
1 stop22h 40m
Multiple Airlines
Deal found 11/2£679
Tue 17/313:05
SCL
-
MAN
1 stop23h 20m
Multiple Airlines
Tue 7/413:35
MAN
-
SCL
1 stop22h 50m
Multiple Airlines
Deal found 11/2£681
Tue 17/313:05
SCL
-
MAN
1 stop23h 20m
Multiple Airlines
Wed 8/406:35
MAN
-
SCL
1 stop18h 15m
Multiple Airlines
Deal found 13/2£685

Find flight deals from Santiago to Manchester

Discover tips and strategies to find the most affordable flight options for your journey from Santiago (SCL) to Manchester (MAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 13 February 2026.

Round-trip from

£661

One-way from

£410

Popular in

January

Cheapest in

February

Average price

£652
17/3-15/4
  • 17/3-15/4
  • 2 total stops
  • 41h 35m total
  • Santiago to Manchester
Search Deals
20/3
  • 20/3
  • 2 total stops
  • 36h 20m total
  • Santiago to Manchester
Search Deals
Highest demand for flights based on searches. 3% potential increase in price (£27 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease (£26 potential savings vs. average return price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Santiago to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 13 February 2026.
Use the filters below to find and compare flights from Santiago to Manchester that are best for you.

Fly from

Santiago

Fly to

Manchester

Route

Depart

Return

Price

SantiagoManchester

SCL - MAN

SCLMAN

Santiago Arturo Merino Benitez

Tue 17/3

13:05-15:25

1 stop23h 20m

Manchester

Tue 7/4

13:35-07:25

1 stop22h 50m

£668

SantiagoManchester

SCL - MAN

SCLMAN

Santiago Arturo Merino Benitez

Wed 18/3

13:05-14:25

1 stop22h 20m

Manchester

Wed 8/4

06:35-19:50

1 stop18h 15m

£712

SantiagoManchester

SCL - MAN

SCLMAN

Santiago Arturo Merino Benitez

Wed 18/3

13:05-14:25

1 stop22h 20m

Manchester

Mon 6/4

14:30-07:25

1 stop21h 55m

£735

SantiagoManchester

SCL - MAN

SCLMAN

Santiago Arturo Merino Benitez

Wed 18/3

12:05-10:10

2 stops19h 05m

Manchester

Tue 7/4

10:55-07:50

1 stop25h 55m

£738

SantiagoManchester

SCL - MAN

SCLMAN

Santiago Arturo Merino Benitez

Wed 18/3

12:05-10:10

2 stops19h 05m

Manchester

Wed 8/4

20:50-08:45

2 stops40h 55m

£754

SantiagoManchester

SCL - MAN

SCLMAN

Santiago Arturo Merino Benitez

Thu 19/3

11:55-12:30

1 stop21h 35m

Manchester

Thu 9/4

07:05-04:45

2 stops50h 40m

£757

SantiagoManchester

SCL - MAN

SCLMAN

Santiago Arturo Merino Benitez

Thu 19/3

12:05-10:10

1 stop19h 05m

Manchester

Mon 6/4

20:50-08:45

2 stops40h 55m

£766

SantiagoManchester

SCL - MAN

SCLMAN

Santiago Arturo Merino Benitez

Tue 17/3

11:55-11:50

1 stop20h 55m

Manchester

Wed 8/4

18:55-04:45

2 stops38h 50m

£781

SantiagoManchester

SCL - MAN

SCLMAN

Santiago Arturo Merino Benitez

Tue 17/3

23:55-17:40

1 stop38h 45m

Manchester

Sat 4/4

09:30-21:20

1 stop39h 50m

£802

SantiagoManchester

SCL - MAN

SCLMAN

Santiago Arturo Merino Benitez

Sun 15/3

16:00-14:55

1 stop19h 55m

Manchester

Tue 14/4

13:35-13:35

2 stops29h 00m

£811

Flights are sorted by cheapest return flights first.

Deals found on 11/2

Showing 1-10 of 16 results
1
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Best time to book a flight from Santiago to Manchester

Have a flexible travel schedule? Discover the best time to fly to Manchester from Santiago with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santiago to Manchester

What is the cheapest month to book a flight from Santiago to Manchester?

Currently, February is the cheapest month in which you can book a flight from Santiago to Manchester (average of £538). Flying from Santiago to Manchester in April is currently the most expensive (average of £1,082). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost for a return flight from Santiago to Manchester?

Related info for your journey

Find useful and relevant information for your journey from Santiago to Manchester. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santiago to Manchester?

    A quick flight from Santiago to Manchester can take about 19h 05m. KLM provides one of the quickest options available for as low as £754. The distance between Santiago and Manchester is about 7251 mi.

  • Can I find deals for flights from Santiago to Manchester that include hotel bookings?

    Yes. In addition to deals on Santiago to Manchester flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Santiago to Manchester?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to Manchester.

  • Can I find deals for business class flights from Santiago to Manchester?

    Yes. Cheapflights offers flight deals from Santiago to Manchester by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santiago to Manchester?

    Currently, February is the cheapest month in which you can book a flight from Santiago to Manchester (average of £538). Flying from Santiago to Manchester in April is currently the most expensive (average of £1,082). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Manchester?

Book flights to Manchester if you plan to visit one of these locations
Windermere
Llandudno
Bradford
Lincoln
Derby
Harrogate
Stoke-on-Trent
Otley
Southport
Lancaster
Telford
Bolton
Preston
Wakefield
Salford
Huddersfield
Stockport
Warrington
Macclesfield
Rochdale

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Can Cheapflights find flights from Santiago to Manchester with no change fees?

Need flexible booking options for your flight to Manchester from Santiago? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

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Of course! You can now track prices for flights from Santiago to Manchester and get an alert from Cheapflights when they change. Have a valid email address ready and click the bell icon next to the flight deals above to set up your price alerts.

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