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Cheap flights from Santiago to Manchester from £339

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 24/3. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — MAN
28 Feb — 7 Mar1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Santiago to Manchester

Enter your travel dates to find the best prices.

Cheapest flights from Santiago to Manchester
Explore the most affordable flight options available from Santiago to Manchester. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 29 January 2026.

Mon 2/1120:55
SCL
-
MAN
2 stops42h 00m
Multiple Airlines
Wed 25/1109:10
MAN
-
SCL
2 stops30h 05m
Multiple Airlines
Deal found 29/1£628
Fri 13/323:55
SCL
-
MAN
1 stop19h 55m
Multiple Airlines
Fri 20/306:15
MAN
-
SCL
1 stop19h 00m
Multiple Airlines
Deal found 27/1£702
Thu 12/321:00
SCL
-
MAN
1 stop21h 15m
Multiple Airlines
Tue 24/315:50
MAN
-
SCL
2 stops26h 40m
Multiple Airlines
Deal found 28/1£710
Tue 24/312:05
SCL
-
MAN
1 stop19h 05m
Air France
Tue 31/310:55
MAN
-
SCL
1 stop25h 55m
Air France
Deal found 29/1£751
Mon 13/423:00
SCL
-
MAN
2 stops41h 50m
Multiple Airlines
Mon 20/412:55
MAN
-
SCL
1 stop24h 50m
Multiple Airlines
Deal found 27/1£756
Tue 10/313:05
SCL
-
MAN
1 stop25h 35m
Multiple Airlines
Tue 7/414:00
MAN
-
SCL
2 stops22h 25m
Multiple Airlines
Deal found 26/1£768
Tue 10/312:35
SCL
-
MAN
2 stops28h 30m
KLM
Tue 7/420:50
MAN
-
SCL
2 stops40h 55m
KLM
Deal found 26/1£772
Tue 10/313:05
SCL
-
MAN
1 stop25h 35m
Iberia
Tue 7/409:30
MAN
-
SCL
1 stop26h 55m
Iberia
Deal found 26/1£776

Find flight deals from Santiago to Manchester

Discover tips and strategies to find the most affordable flight options for your journey from Santiago (SCL) to Manchester (MAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 29 January 2026.

Round-trip from

£702

One-way from

£339

Popular in

January

Cheapest in

February

Average price

£1,327
13/3-20/3
  • 13/3-20/3
  • 2 total stops
  • 38h 55m total
  • Santiago to Manchester
Search Deals
24/3
  • 24/3
  • 3 total stops
  • 34h 55m total
  • Santiago to Manchester
Search Deals
Highest demand for flights based on searches. 3% potential increase in price (£28 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease (£24 potential savings vs. average return price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Santiago to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 29 January 2026.
Use the filters below to find and compare flights from Santiago to Manchester that are best for you.

Fly from

Santiago

Fly to

Manchester

Route

Depart

Return

Price

SantiagoManchester

SCL - MAN

SCLMAN

Santiago Arturo Merino Benitez

Tue 10/3

12:35-08:20

2 stops40h 45m

Manchester

Tue 7/4

14:55-07:50

1 stop21h 55m

£768

SantiagoManchester

SCL - MAN

SCLMAN

Santiago Arturo Merino Benitez

Tue 10/3

12:35-20:05

2 stops28h 30m

Manchester

Tue 7/4

20:50-08:45

2 stops40h 55m

£772

SantiagoManchester

SCL - MAN

SCLMAN

Santiago Arturo Merino Benitez

Wed 11/3

01:40-21:15

3 stops40h 35m

Manchester

Tue 24/3

06:20-15:20

2 stops36h 00m

£781

SantiagoManchester

SCL - MAN

SCLMAN

Santiago Arturo Merino Benitez

Tue 14/4

23:00-11:40

2 stops31h 40m

Manchester

Mon 20/4

18:10-08:45

1 stop19h 35m

£782

SantiagoManchester

SCL - MAN

SCLMAN

Santiago Arturo Merino Benitez

Tue 24/3

12:05-10:10

2 stops19h 05m

Manchester

Tue 31/3

14:55-08:50

1 stop21h 55m

£800

SantiagoManchester

SCL - MAN

SCLMAN

Santiago Arturo Merino Benitez

Tue 19/5

10:10-10:00

1 stop18h 50m

Manchester

Tue 2/6

14:55-07:50

1 stop21h 55m

£802

SantiagoManchester

SCL - MAN

SCLMAN

Santiago Arturo Merino Benitez

Tue 19/5

10:15-16:45

2 stops25h 30m

Manchester

Tue 2/6

10:55-07:50

1 stop25h 55m

£816

SantiagoManchester

SCL - MAN

SCLMAN

Santiago Arturo Merino Benitez

Wed 15/4

10:30-00:55

2 stops33h 25m

Manchester

Mon 20/4

12:55-08:45

1 stop24h 50m

£818

SantiagoManchester

SCL - MAN

SCLMAN

Santiago Arturo Merino Benitez

Tue 24/3

21:05-11:00

3 stops34h 55m

£339

SantiagoManchester

SCL - MAN

SCLMAN

Santiago Arturo Merino Benitez

Wed 25/3

21:05-16:20

3 stops40h 15m

£347

Flights are sorted by cheapest return flights first.

Deals found on 28/1

Showing 1-10 of 14 results
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Best time to book a flight from Santiago to Manchester

Have a flexible travel schedule? Discover the best time to fly to Manchester from Santiago with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santiago to Manchester

What is the cheapest month to book a flight from Santiago to Manchester?

Currently, February is the cheapest month in which you can book a flight from Santiago to Manchester (average of £542). Flying from Santiago to Manchester in April is currently the most expensive (average of £1,069). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Santiago to Manchester. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santiago to Manchester?

    A quick flight from Santiago to Manchester can take about 28h 30m. KLM provides one of the quickest options available for as low as £772. The distance between Santiago and Manchester is about 7251 mi.

  • Can I find deals for flights from Santiago to Manchester that include hotel bookings?

    Yes. In addition to deals on Santiago to Manchester flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Santiago to Manchester?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to Manchester.

  • Can I find deals for business class flights from Santiago to Manchester?

    Yes. Cheapflights offers flight deals from Santiago to Manchester by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santiago to Manchester?

    Currently, February is the cheapest month in which you can book a flight from Santiago to Manchester (average of £542). Flying from Santiago to Manchester in April is currently the most expensive (average of £1,069). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Manchester?

Book flights to Manchester if you plan to visit one of these locations
Windermere
Llandudno
Bradford
Lincoln
Derby
Harrogate
Stoke-on-Trent
Otley
Southport
Telford
Lancaster
Wakefield
Bolton
Preston
Salford
Huddersfield
Stockport
Rochdale
Blackburn
Skipton

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Why should you use Cheapflights to find cheap flight tickets from Santiago to Manchester?

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Can Cheapflights find flights from Santiago to Manchester with no change fees?

Need flexible booking options for your flight to Manchester from Santiago? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

Can Cheapflights notify me if prices for flights from Santiago to Manchester become cheaper?

Of course! You can now track prices for flights from Santiago to Manchester and get an alert from Cheapflights when they change. Have a valid email address ready and click the bell icon next to the flight deals above to set up your price alerts.

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