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Cheap flights from Santiago to Manchester from £410

SCL — MAN
2 Dec — 9 Dec1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Santiago to Manchester

Enter your travel dates to find the best prices.

Cheapest flights from Santiago to Manchester

Thu 26/1121:05 -
1 stop22h 40m
Thu 3/1206:15 -
1 stop17h 30m
Deal found 29/10£660
Fri 27/1108:25 -
2 stops27h 35m
Fri 4/1207:40 -
3 stops31h 35m
Deal found 30/10£789
Thu 26/1112:50 -
1 stop16h 35m
Mon 14/1216:25 -
2 stops21h 50m
Deal found 29/10£808
Sun 22/1112:50 -
1 stop16h 25m
Mon 14/1216:25 -
2 stops21h 50m
Deal found 29/10£810
Thu 26/1112:50 -
1 stop16h 35m
Sun 13/1218:50 -
2 stops23h 10m
Deal found 29/10£823
Sun 22/1112:50 -
1 stop16h 25m
Sun 13/1218:50 -
2 stops23h 10m
Deal found 29/10£825
Thu 24/1212:50 -
2 stops21h 05m
Tue 5/113:35 -
2 stops34h 10m
Deal found 1/11£830
Sun 6/1216:00 -
1 stop21h 00m
Sat 2/106:30 -
2 stops26h 15m
Deal found 1/11£833

Find flight deals from Santiago to Manchester

Round-trip from

£660

One-way from

£410

Popular in

April

Cheapest in

November

Average price

£802
26/11-3/12
  • 26/11-3/12
  • 2 total stops
  • 40h 10m total
  • Santiago to Manchester
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5/4-31/12
  • 5/4-31/12
  • 3 total stops
  • 44h 30m total
  • Santiago to Manchester
Search Deals
Highest demand for flights based on searches. 9% potential increase in price (£88 potential increase over avg. return price).
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Cheapest flight prices on average. 4% potential price decrease (£39 potential savings vs. average return price).
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Average for round-trip flights in November 2026
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Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Santiago to Manchester that are best for you.

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Depart

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Cheapest return flight

SantiagoManchester

SCL Santiago Arturo Merino Benitez - MAN Manchester

SCLMAN

Santiago Arturo Merino Benitez

Fri 9/4

06:40-08:10

3 stops44h 30m

Manchester

Wed 31/12

00:00-20:00

Nonstop0h 00m

£411

SantiagoManchester

SCL Santiago Arturo Merino Benitez - MAN Manchester

SCLMAN

Santiago Arturo Merino Benitez

Wed 7/4

06:40-22:55

2 stops35h 15m

Manchester

Wed 31/12

00:00-20:00

Nonstop0h 00m

£424

SantiagoManchester

SCL Santiago Arturo Merino Benitez - MAN Manchester

SCLMAN

Santiago Arturo Merino Benitez

Thu 8/4

06:40-10:45

2 stops47h 05m

Manchester

Wed 31/12

00:00-20:00

Nonstop0h 00m

£427

SantiagoManchester

SCL Santiago Arturo Merino Benitez - MAN Manchester

SCLMAN

Santiago Arturo Merino Benitez

Tue 6/4

15:20-11:30

3 stops39h 10m

Manchester

Wed 31/12

00:00-20:00

Nonstop0h 00m

£465
Fastest return journey

SantiagoManchester

SCL Santiago Arturo Merino Benitez - MAN Manchester

SCLMAN

Santiago Arturo Merino Benitez

Sun 4/4

06:40-20:25

2 stops32h 45m

Manchester

Wed 31/12

00:00-20:00

Nonstop0h 00m

£473

SantiagoManchester

SCL Santiago Arturo Merino Benitez - MAN Manchester

SCLMAN

Santiago Arturo Merino Benitez

Thu 3/12

22:45-11:30

2 stops33h 45m

Manchester

Wed 31/12

00:00-20:00

Nonstop0h 00m

£592

SantiagoManchester

SCL Santiago Arturo Merino Benitez - MAN Manchester

SCLMAN

Santiago Arturo Merino Benitez

Thu 21/1

21:55-08:45

1 stop31h 50m

Manchester

Sun 31/1

12:15-12:15

2 stops27h 00m

£818

SantiagoManchester

SCL Santiago Arturo Merino Benitez - MAN Manchester

SCLMAN

Santiago Arturo Merino Benitez

Sun 24/1

08:25-16:00

3 stops28h 35m

Manchester

Thu 4/2

06:15-06:50

2 stops27h 35m

£842

SantiagoManchester

SCL Santiago Arturo Merino Benitez - MAN Manchester

SCLMAN

Santiago Arturo Merino Benitez

Sun 24/1

08:25-10:20

2 stops22h 55m

Manchester

Sun 31/1

09:05-12:15

2 stops30h 10m

£857

SantiagoManchester

SCL Santiago Arturo Merino Benitez - MAN Manchester

SCLMAN

Santiago Arturo Merino Benitez

Mon 25/1

21:55-16:30

2 stops39h 35m

Manchester

Wed 10/2

09:05-12:15

2 stops30h 10m

£908

Flights are sorted by cheapest return flights first.

Deals found on 29/10

Showing 1-10 of 18 resultsSorted by cheapest first
1
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Best time to book a flight from Santiago to Manchester

Have a flexible travel schedule? Discover the best time to fly to Manchester from Santiago with our price prediction graph.
Estimated return price

Cheapflights Insights

Everything you need to know about your flight from Santiago to Manchester

What is the cheapest month to book a flight from Santiago to Manchester?

Currently, November is the cheapest month in which you can book a flight from Santiago to Manchester (average of £802). Flying from Santiago to Manchester in April is currently the most expensive (average of £1,691). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

  • Can I find deals for flights from Santiago to Manchester that include hotel bookings?

    Yes. In addition to deals on Santiago to Manchester flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Santiago to Manchester?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to Manchester.

  • Can I find deals for business class flights from Santiago to Manchester?

    Yes. Cheapflights offers flight deals from Santiago to Manchester by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santiago to Manchester?

    Currently, November is the cheapest month in which you can book a flight from Santiago to Manchester (average of £802). Flying from Santiago to Manchester in April is currently the most expensive (average of £1,691). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Manchester?

Book flights to Manchester if you plan to visit one of these locations
Llandudno
Windermere
Bradford
Stoke-on-Trent
Harrogate
Southport
Salford
Warrington
Derby
Telford
Lincoln
Shrewsbury
Otley
Preston
Burnley
Bolton
Wilmslow
Huddersfield
Wakefield
Stafford

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How does Cheapflights help users find flights from Santiago to Manchester?

Deals for Santiago to Manchester flights are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose better, like price, airport, cabin class, and plenty of other options.

Why should you use Cheapflights to find cheap flight tickets from Santiago to Manchester?

Millions of users choose and trust Cheapflights to book the best flight deals from Santiago to Manchester for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.

Can Cheapflights find flights from Santiago to Manchester with no change fees?

Need flexible booking options for your flight to Manchester from Santiago? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

Can Cheapflights notify me if prices for flights from Santiago to Manchester become cheaper?

Of course! You can now track prices for flights from Santiago to Manchester and get an alert from Cheapflights when they change. Have a valid email address ready and click the bell icon next to the flight deals above to set up your price alerts.

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