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Cheap flights from Santiago to Manchester from £355

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 18/5. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — MAN
12 Feb — 19 Feb1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Santiago to Manchester

Discover tips and strategies to find the most affordable flight options for your journey from Santiago (SCL) to Manchester (MAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 13 January 2026.

Round-trip from

£635

One-way from

£355

Popular in

January

Cheapest in

February

Average price

£1,360
25/2-4/3
  • 25/2-4/3
  • 5 total stops
  • 58h 35m total
  • Santiago to Manchester
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18/5
  • 18/5
  • 3 total stops
  • 51h 55m total
  • Santiago to Manchester
Search Deals
Highest demand for flights based on searches. 3% potential increase in price (£30 potential increase over avg. return price).
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Cheapest flight prices on average. 3% potential price decrease (£25 potential savings vs. average return price).
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Average for round-trip flights in January 2026
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Find flight deals from Santiago to Manchester

Enter your travel dates to find the best prices.

Cheapest flights from Santiago to Manchester
Explore the most affordable flight options available from Santiago to Manchester. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 13 January 2026.

Wed 25/208:25
SCL
-
MAN
2 stops27h 00m
Multiple Airlines
Wed 4/307:40
MAN
-
SCL
3 stops31h 35m
Multiple Airlines
Deal found 11/1£635
Tue 24/307:25
SCL
-
MAN
2 stops31h 15m
LATAM Airlines
Tue 31/315:20
MAN
-
SCL
2 stops34h 50m
LATAM Airlines
Deal found 12/1£648
Tue 10/313:40
SCL
-
MAN
2 stops25h 00m
LATAM Airlines
Tue 7/415:20
MAN
-
SCL
2 stops24h 10m
LATAM Airlines
Deal found 10/1£659
Tue 3/315:00
SCL
-
MAN
2 stops23h 35m
Multiple Airlines
Tue 14/415:20
MAN
-
SCL
2 stops24h 10m
Multiple Airlines
Deal found 10/1£723

Cheapflights Fare Finder

 
Customise your flight search to find flights from Santiago to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 13 January 2026.
Use the filters below to find and compare flights from Santiago to Manchester that are best for you.

Fly from

Santiago

Fly to

Manchester

Route

Depart

Return

Price

SantiagoManchester

SCL - MAN

SCLMAN

Santiago Arturo Merino Benitez

Tue 10/3

13:40-17:40

2 stops25h 00m

Manchester

Tue 7/4

15:20-10:30

2 stops24h 10m

£659

SantiagoManchester

SCL - MAN

SCLMAN

Santiago Arturo Merino Benitez

Tue 3/3

15:00-17:35

2 stops23h 35m

Manchester

Tue 14/4

15:20-10:30

2 stops24h 10m

£723

SantiagoManchester

SCL - MAN

SCLMAN

Santiago Arturo Merino Benitez

Wed 25/2

08:25-16:15

3 stops28h 50m

Manchester

Wed 4/3

07:40-12:15

3 stops31h 35m

£731

SantiagoManchester

SCL - MAN

SCLMAN

Santiago Arturo Merino Benitez

Thu 23/4

10:30-11:20

1 stop19h 50m

Manchester

Fri 1/5

05:55-08:45

2 stops31h 50m

£754

SantiagoManchester

SCL - MAN

SCLMAN

Santiago Arturo Merino Benitez

Tue 10/3

13:05-17:40

1 stop25h 35m

Manchester

Tue 7/4

09:30-07:25

1 stop26h 55m

£762

SantiagoManchester

SCL - MAN

SCLMAN

Santiago Arturo Merino Benitez

Mon 2/3

13:05-17:40

1 stop25h 35m

Manchester

Sun 8/3

18:05-21:59

2 stops30h 54m

£768

SantiagoManchester

SCL - MAN

SCLMAN

Santiago Arturo Merino Benitez

Tue 3/3

15:00-17:40

2 stops23h 40m

Manchester

Tue 14/4

15:20-10:30

3 stops24h 10m

£779

SantiagoManchester

SCL - MAN

SCLMAN

Santiago Arturo Merino Benitez

Mon 18/5

00:55-09:50

3 stops51h 55m

£355

SantiagoManchester

SCL - MAN

SCLMAN

Santiago Arturo Merino Benitez

Tue 10/2

07:25-11:00

3 stops48h 35m

£396

SantiagoManchester

SCL - MAN

SCLMAN

Santiago Arturo Merino Benitez

Mon 2/2

16:25-10:35

3 stops39h 10m

£451

Flights are sorted by cheapest return flights first.

Deals found on 11/1

Showing 1-10 of 13 results
1
2

Best time to book a flight from Santiago to Manchester

Have a flexible travel schedule? Discover the best time to fly to Manchester from Santiago with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santiago to Manchester

What is the cheapest month to book a flight from Santiago to Manchester?

Currently, February is the cheapest month in which you can book a flight from Santiago to Manchester (average of £555). Flying from Santiago to Manchester in April is currently the most expensive (average of £1,096). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost for a return flight from Santiago to Manchester?

Related info for your journey

Find useful and relevant information for your journey from Santiago to Manchester. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santiago to Manchester?

    A quick flight from Santiago to Manchester can take about 25h. LATAM Airlines provides one of the quickest options available for as low as £659. The distance between Santiago and Manchester is about 7251 mi.

  • Can I find deals for flights from Santiago to Manchester that include hotel bookings?

    Yes. In addition to deals on Santiago to Manchester flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Santiago to Manchester?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to Manchester.

  • Can I find deals for business class flights from Santiago to Manchester?

    Yes. Cheapflights offers flight deals from Santiago to Manchester by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santiago to Manchester?

    Currently, February is the cheapest month in which you can book a flight from Santiago to Manchester (average of £555). Flying from Santiago to Manchester in April is currently the most expensive (average of £1,096). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Manchester?

Book flights to Manchester if you plan to visit one of these locations
Windermere
Llandudno
Lincoln
Bradford
Derby
Harrogate
Otley
Stoke-on-Trent
Telford
Southport
Lancaster
Morecambe
Wakefield
Bolton
Preston
Stockport
Salford
Huddersfield
Rochdale
Skipton

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Can Cheapflights find flights from Santiago to Manchester with no change fees?

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Of course! You can now track prices for flights from Santiago to Manchester and get an alert from Cheapflights when they change. Have a valid email address ready and click the bell icon next to the flight deals above to set up your price alerts.

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