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Cheap flights from St. Louis to Manchester from £275

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/11. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MAN
17 Oct — 24 Oct1
1 adult
1 adult, Economy

Cheapflights Tip: The best prices from Lambert-St Louis to Manchester are usually found in February or August, booked 43 days in advance, depart on a Monday or Tuesday and return on a Wednesday

Cheap flight deals from St. Louis to Manchester

Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Manchester (MAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 17 September 2025.

Round-trip from

£504

One-way from

£275

Popular in

June

Cheapest in

February

Average price

£562
American Airlines
  • American Airlines
  • 7/10-15/10
  • 4 total stops
  • 34h 01m total
  • St. Louis to Manchester
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1/11
  • 1/11
  • 3 total stops
  • 45h 40m total
  • St. Louis to Manchester
Search Deals
Highest demand for flights based on searches. 27% potential increase in price (£181 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease (£25 potential savings vs. average return price).
Search Deals
Average for round-trip flights in September 2025
Search Deals

Find flight deals from St. Louis to Manchester

Cheapest flights from St. Louis to Manchester
Explore the most affordable flight options available from St. Louis to Manchester. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 17 September 2025.

Tue 7/1014:15STL - MAN
2 stops16h 55mAmerican Airlines
Wed 15/1009:20MAN - STL
2 stops17h 06mAmerican Airlines
Deal found 15/9£504
Wed 10/1217:54STL - MAN
2 stops18h 51mBritish Airways
Mon 15/1220:05MAN - STL
2 stops26h 45mBritish Airways
Deal found 16/9£505
Mon 29/1219:03STL - MAN
1 stop33h 27mDelta
Thu 15/113:30MAN - STL
1 stop13h 09mDelta
Deal found 15/9£506
Tue 30/1213:21STL - MAN
2 stops14h 49mDelta
Fri 16/113:00MAN - STL
2 stops16h 40mDelta
Deal found 15/9£509
Mon 29/1219:03STL - MAN
1 stop33h 27mDelta
Wed 14/113:00MAN - STL
2 stops16h 40mDelta
Deal found 15/9£510
Mon 29/1219:03STL - MAN
1 stop33h 27mDelta
Tue 20/113:30MAN - STL
1 stop25h 34mDelta
Deal found 15/9£510
Mon 29/1208:05STL - MAN
2 stops22h 15mUnited Airlines
Tue 20/106:00MAN - STL
2 stops39h 29mUnited Airlines
Deal found 15/9£517
Tue 7/1007:05STL - MAN
1 stop19h 30mDelta
Wed 15/1008:55MAN - STL
2 stops20h 12mDelta
Deal found 15/9£521
Mon 29/1208:05STL - MAN
2 stops22h 15mUnited Airlines
Mon 19/109:30MAN - STL
2 stops35h 00mUnited Airlines
Deal found 15/9£534
Wed 24/1218:35STL - MAN
2 stops16h 20mLufthansa
Wed 14/106:00MAN - STL
1 stop13h 55mLufthansa
Deal found 15/9£537

Cheapflights Fare Finder

 
Customise your flight search to find flights from St. Louis to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 17 September 2025.
Use the filters below to find and compare flights from St. Louis to Manchester that are best for you.

Fly from

St. Louis

Fly to

Manchester

Route

Depart

Return

Price

St. LouisManchester

STL - MAN

STLMAN

Lambert-St Louis

Wed 10/12

17:54-18:45

2 stops18h 51m

Manchester

Mon 15/12

20:05-16:50

2 stops26h 45m

£505

St. LouisManchester

STL - MAN

STLMAN

Lambert-St Louis

Tue 30/12

17:55-16:05

2 stops16h 10m

Manchester

Wed 14/1

13:30-23:40

1 stop16h 10m

£506

St. LouisManchester

STL - MAN

STLMAN

Lambert-St Louis

Mon 29/12

19:03-10:30

1 stop33h 27m

Manchester

Wed 14/1

13:30-23:40

1 stop16h 10m

£506

St. LouisManchester

STL - MAN

STLMAN

Lambert-St Louis

Tue 30/12

13:21-10:10

2 stops14h 49m

Manchester

Fri 16/1

13:00-23:40

2 stops16h 40m

£509

St. LouisManchester

STL - MAN

STLMAN

Lambert-St Louis

Tue 30/12

13:21-10:10

2 stops14h 49m

Manchester

Tue 20/1

13:30-10:50

1 stop27h 20m

£510

St. LouisManchester

STL - MAN

STLMAN

Lambert-St Louis

Mon 29/12

08:05-12:20

2 stops22h 15m

Manchester

Thu 15/1

13:00-15:29

2 stops32h 29m

£517

St. LouisManchester

STL - MAN

STLMAN

Lambert-St Louis

Mon 29/12

15:15-12:45

2 stops15h 30m

Manchester

Thu 15/1

13:30-20:39

1 stop13h 09m

£524

St. LouisManchester

STL - MAN

STLMAN

Lambert-St Louis

Mon 29/12

06:30-12:20

2 stops23h 50m

Manchester

Tue 20/1

09:25-13:55

1 stop34h 30m

£527

St. LouisManchester

STL - MAN

STLMAN

Lambert-St Louis

Tue 6/1

13:30-08:50

2 stops13h 20m

Manchester

Sun 11/1

08:55-20:23

2 stops17h 28m

£534

St. LouisManchester

STL - MAN

STLMAN

Lambert-St Louis

Sun 28/12

18:35-12:20

2 stops35h 45m

Manchester

Wed 14/1

06:00-21:13

2 stops21h 13m

£546

Flights are sorted by cheapest return flights first.

Deals found on 16/9

Showing 1-10 of 15 results
1
2

Best time to book a flight from St. Louis to Manchester

Have a flexible travel schedule? Discover the best time to fly to Manchester from St. Louis with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Manchester

How far ahead should I book a flight from St. Louis to Manchester?

Use this chart to determine the optimal time to book a return flight from St. Louis to Manchester. Price data was last updated on 12 September 2025.

The price you pay for your flight from St. Louis to Manchester may vary depending on when you book. For the best chance of a lower fare, look to book 43 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from St. Louis to Manchester?

Currently, January is the cheapest month in which you can book a flight from St. Louis to Manchester (average of £117). Flying from St. Louis to Manchester in September is currently the most expensive (average of £143). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from STL to MAN?

Find hourly flight availability from St. Louis to Manchester. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 17 September 2025.

It’s optimal to fly from St. Louis to Manchester in the morning. By choosing this option you can save up to 22% on the cost of your flight, compared to a flight in the afternoon.

Reviews of airlines servicing Manchester

Get insights into the airlines that provide service to Manchester. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Manchester. Reviews last updated 17 September 2025.
See what other customers who have flown with Virgin Atlantic from St. Louis to Manchester have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Virgin Atlantic
7.4
Good
664 reviews
Check prices

Comfort

7.3

Food

6.9

Crew

8.1

Entertainment

7.5

Boarding

7.7

Overall

7.4

Reviews

1 / 20
6.0
Good

Pratap,Aug 2025

JFK - LHR

The flight is clean, food good and the staff are excellent! Very professional, polite and accommodating. The seat itself is really mediocre. Can’t believe there is not inch of storage space. Believe it or not it there is not place even to put away your phone or pen!! Very very surprising and terribly inconvenient. No coat hanger hook either. Had to give it away. ALL IN ALL VERY INCONVENIENT business class seat compared to their peers. What is even more surprising is that this on their relatively new fleet of Airbus A350-1000. I was having com platelets different expectations of Virgin and this has disappointed me. Everything else is just as good and as you would expect from Virgin!
Virgin Atlantic
7.4
Good
664 reviews
Virgin Atlantic
7.4
Good
664 reviews
Check prices

Comfort

7.3

Food

6.9

Crew

8.1

Entertainment

7.5

Boarding

7.7

Overall

7.4

Reviews

1 / 20
6.0
Good

Pratap,Aug 2025

JFK - LHR

The flight is clean, food good and the staff are excellent! Very professional, polite and accommodating. The seat itself is really mediocre. Can’t believe there is not inch of storage space. Believe it or not it there is not place even to put away your phone or pen!! Very very surprising and terribly inconvenient. No coat hanger hook either. Had to give it away. ALL IN ALL VERY INCONVENIENT business class seat compared to their peers. What is even more surprising is that this on their relatively new fleet of Airbus A350-1000. I was having com platelets different expectations of Virgin and this has disappointed me. Everything else is just as good and as you would expect from Virgin!

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Manchester. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from St. Louis to Manchester?

    Departing from St. Louis to Manchester will take you 16h 10m. The distance from St. Louis to Manchester is about 4061 mi. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.

  • What is the cheapest airline to fly from St. Louis to Manchester round-trip?

    Our cheapest airline available from St. Louis to Manchester is Virgin Atlantic. Our recent data shows that you can find tickets from as low as £475 on this airline. Virgin Atlantic is priced at 27% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from St. Louis to Manchester that include hotel bookings?

    Yes. In addition to deals on St. Louis to Manchester flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Manchester?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Manchester.

  • Can I find deals for business class flights from St. Louis to Manchester?

    Yes. Cheapflights offers flight deals from St. Louis to Manchester by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to Manchester?

    Currently, January is the cheapest month in which you can book a flight from St. Louis to Manchester (average of £117). Flying from St. Louis to Manchester in September is currently the most expensive (average of £143). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Manchester?

Book flights to Manchester if you plan to visit one of these locations
Windermere
Llandudno
Derby
Lincoln
Bradford
Harrogate
Preston
Stoke-on-Trent
Stockport
Wakefield
Southport
Bolton
Blackburn
Morecambe
Telford
Lancaster
Salford
Rochdale
Huddersfield
Wigan

Browse thousands of different options on Cheapflights for your next trip

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Top airline flying from St. Louis to Manchester

Discover the top airline that operate flights from St. Louis to Manchester. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 17 September 2025.
AirlineCheapestAverageFlexibilityOn-time
Virgin AtlanticCheapest£475Average£541FlexibilityNo cancel feeOn-time72%
Search Virgin Atlantic flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from St. Louis to Manchester?

Cheapflights makes it easy to find St. Louis to Manchester flights by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

Why should you use Cheapflights to find cheap flight tickets from St. Louis to Manchester?

By finding flights from multiple airlines and providers at completely no cost, Cheapflights helps millions of users like you annually find the best flights to Manchester from St. Louis.

Can Cheapflights find flights from St. Louis to Manchester with no change fees?

Cheapflights does show flights with no change fees to all users. To see these options for flights from St. Louis to Manchester, users can toggle the no change fees filter when performing a flight search.

Can Cheapflights notify me if prices for flights from St. Louis to Manchester become cheaper?

Yes, Cheapflights has a feature called Price Alert, which notifies users when flight prices change. Track prices for your flight to Manchester from St. Louis today and book when prices fit your budget.

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