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Cheap flights from St. Louis to Manchester from £418

This is the cheapest retur flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/10. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MAN
25 Feb — 4 Mar1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from St. Louis to Manchester

Enter your travel dates to find the best prices.

Cheapest flights from St. Louis to Manchester
Explore the most affordable flight options available from St. Louis to Manchester. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 26 January 2026.

Mon 5/1013:30
STL
-
MAN
2 stops34h 55m
Air Canada
Thu 8/1006:05
MAN
-
STL
2 stops19h 25m
Air Canada
Deal found 25/1£418
Wed 11/307:40
STL
-
MAN
2 stops21h 40m
United Airlines
Wed 18/306:10
MAN
-
STL
2 stops19h 57m
United Airlines
Deal found 25/1£470
Tue 5/517:35
STL
-
MAN
2 stops13h 35m
Delta
Tue 19/513:00
MAN
-
STL
1 stop16h 38m
Delta
Deal found 26/1£483
Wed 29/415:30
STL
-
MAN
1 stop12h 40m
Lufthansa
Sun 3/505:55
MAN
-
STL
1 stop13h 30m
Lufthansa
Deal found 24/1£501
Mon 5/1007:20
STL
-
MAN
1 stop19h 30m
Delta
Thu 8/1013:00
MAN
-
STL
1 stop16h 39m
Delta
Deal found 25/1£505
Wed 29/414:12
STL
-
MAN
2 stops13h 38m
American Airlines
Sun 3/507:45
MAN
-
STL
2 stops15h 27m
American Airlines
Deal found 24/1£519
Sat 11/407:45
STL
-
MAN
2 stops27h 35m
United Airlines
Wed 22/406:05
MAN
-
STL
2 stops21h 03m
United Airlines
Deal found 25/1£530
Sat 11/412:11
STL
-
MAN
2 stops28h 24m
British Airways
Wed 22/413:50
MAN
-
STL
1 stop11h 40m
British Airways
Deal found 25/1£551
Tue 5/521:35
STL
-
MAN
1 stop11h 35m
British Airways
Tue 19/514:00
MAN
-
STL
1 stop11h 30m
British Airways
Deal found 26/1£558

Find flight deals from St. Louis to Manchester

Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Manchester (MAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 26 January 2026.

Round-trip from

£470

Popular in

June

Cheapest in

August
United Airlines
  • United Airlines
  • 11/3-18/3
  • 4 total stops
  • 41h 37m total
  • St. Louis to Manchester
Search Deals
Highest demand for flights based on searches. 20% potential increase in price (£126 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease (£26 potential savings vs. average return price).
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from St. Louis to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 26 January 2026.
Use the filters below to find and compare flights from St. Louis to Manchester that are best for you.

Fly from

St. Louis

Fly to

Manchester

Route

Depart

Return

Price

St. LouisManchester

STL - MAN

STLMAN

Lambert-St Louis

Tue 5/5

17:29-13:10

2 stops13h 41m

Manchester

Tue 19/5

13:00-23:38

1 stop16h 38m

£483

St. LouisManchester

STL - MAN

STLMAN

Lambert-St Louis

Tue 5/5

13:00-10:25

2 stops15h 25m

Manchester

Tue 19/5

06:05-20:05

2 stops20h 00m

£483

St. LouisManchester

STL - MAN

STLMAN

Lambert-St Louis

Wed 29/4

15:30-10:10

1 stop12h 40m

Manchester

Sun 3/5

05:55-13:25

1 stop13h 30m

£501

St. LouisManchester

STL - MAN

STLMAN

Lambert-St Louis

Wed 11/3

07:40-08:40

2 stops20h 00m

Manchester

Wed 18/3

06:00-14:55

1 stop13h 55m

£534

St. LouisManchester

STL - MAN

STLMAN

Lambert-St Louis

Sun 24/5

18:12-16:05

2 stops15h 53m

Manchester

Fri 5/6

10:35-20:26

2 stops15h 51m

£669

St. LouisManchester

STL - MAN

STLMAN

Lambert-St Louis

Tue 26/5

13:00-10:25

2 stops15h 25m

Manchester

Tue 2/6

05:55-13:25

1 stop13h 30m

£697

St. LouisManchester

STL - MAN

STLMAN

Lambert-St Louis

Tue 7/7

12:10-10:25

2 stops16h 15m

Manchester

Tue 21/7

05:55-13:25

1 stop13h 30m

£697

St. LouisManchester

STL - MAN

STLMAN

Lambert-St Louis

Tue 26/5

06:00-08:50

1 stop20h 50m

Manchester

Tue 2/6

13:00-23:38

1 stop16h 38m

£708

St. LouisManchester

STL - MAN

STLMAN

Lambert-St Louis

Tue 12/5

17:30-16:45

2 stops17h 15m

Manchester

Thu 30/7

05:50-16:40

2 stops16h 50m

£710

Flights are sorted by cheapest return flights first.

Deals found on 24/1

Best time to book a flight from St. Louis to Manchester

Have a flexible travel schedule? Discover the best time to fly to Manchester from St. Louis with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Manchester

How far ahead should I book a flight from St. Louis to Manchester?

Use this chart to determine the optimal time to book a return flight from St. Louis to Manchester. Price data was last updated on 23 January 2026.

The price you pay for your flight from St. Louis to Manchester may vary depending on when you book. For the best chance of a lower fare, look to book 74 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

Reviews of airlines servicing Manchester

Get insights into the airlines that provide service to Manchester. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Manchester. Reviews last updated 26 January 2026.
See what other customers who have flown with Virgin Atlantic from St. Louis to Manchester have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Virgin Atlantic
7.5
Good
678 reviews
Check prices

Overall

7.5

Boarding

7.7

Crew

8.2

Food

6.9

Comfort

7.3

Entertainment

7.6

Reviews

1 / 20
6.0
Good

Pratap,Aug 2025

JFK - LHR

The flight is clean, food good and the staff are excellent! Very professional, polite and accommodating. The seat itself is really mediocre. Can’t believe there is not inch of storage space. Believe it or not it there is not place even to put away your phone or pen!! Very very surprising and terribly inconvenient. No coat hanger hook either. Had to give it away. ALL IN ALL VERY INCONVENIENT business class seat compared to their peers. What is even more surprising is that this on their relatively new fleet of Airbus A350-1000. I was having com platelets different expectations of Virgin and this has disappointed me. Everything else is just as good and as you would expect from Virgin!
Virgin Atlantic
7.5
Good
678 reviews
Virgin Atlantic
7.5
Good
678 reviews
Check prices

Overall

7.5

Boarding

7.7

Crew

8.2

Food

6.9

Comfort

7.3

Entertainment

7.6

Reviews

1 / 20
6.0
Good

Pratap,Aug 2025

JFK - LHR

The flight is clean, food good and the staff are excellent! Very professional, polite and accommodating. The seat itself is really mediocre. Can’t believe there is not inch of storage space. Believe it or not it there is not place even to put away your phone or pen!! Very very surprising and terribly inconvenient. No coat hanger hook either. Had to give it away. ALL IN ALL VERY INCONVENIENT business class seat compared to their peers. What is even more surprising is that this on their relatively new fleet of Airbus A350-1000. I was having com platelets different expectations of Virgin and this has disappointed me. Everything else is just as good and as you would expect from Virgin!

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Manchester. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from St. Louis to Manchester?

    Departing from St. Louis to Manchester will take you 13h 41m. The distance from St. Louis to Manchester is about 4061 mi. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.

  • What is the cheapest airline to fly from St. Louis to Manchester round-trip?

    Our cheapest airline available from St. Louis to Manchester is Virgin Atlantic. Our recent data shows that you can find tickets from as low as £427 on this airline. Virgin Atlantic is priced at 37% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from St. Louis to Manchester that include hotel bookings?

    Yes. In addition to deals on St. Louis to Manchester flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Manchester?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Manchester.

  • Can I find deals for business class flights from St. Louis to Manchester?

    Yes. Cheapflights offers flight deals from St. Louis to Manchester by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Travelling to a place near Manchester?

Book flights to Manchester if you plan to visit one of these locations
Windermere
Llandudno
Bradford
Lincoln
Derby
Harrogate
Stoke-on-Trent
Otley
Southport
Telford
Lancaster
Wakefield
Bolton
Preston
Salford
Huddersfield
Stockport
Rochdale
Blackburn
Skipton

Browse thousands of different options on Cheapflights for your next trip

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Top airline flying from St. Louis to Manchester

Discover the top airline that operate flights from St. Louis to Manchester. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 26 January 2026.
AirlineCheapestAverageFlexibilityOn-time
Virgin AtlanticCheapest£427Average£540FlexibilityNo cancel feeOn-time72%
Search Virgin Atlantic flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from St. Louis to Manchester?

Cheapflights makes it easy to find St. Louis to Manchester flights by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

Why should you use Cheapflights to find cheap flight tickets from St. Louis to Manchester?

By finding flights from multiple airlines and providers at completely no cost, Cheapflights helps millions of users like you annually find the best flights to Manchester from St. Louis.

Can Cheapflights find flights from St. Louis to Manchester with no change fees?

Cheapflights does show flights with no change fees to all users. To see these options for flights from St. Louis to Manchester, users can toggle the no change fees filter when performing a flight search.

Can Cheapflights notify me if prices for flights from St. Louis to Manchester become cheaper?

Yes, Cheapflights has a feature called Price Alert, which notifies users when flight prices change. Track prices for your flight to Manchester from St. Louis today and book when prices fit your budget.

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