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Cheap flights from Panama City to Mexico City from £123

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 31/5. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — MEX
5 May — 12 May1
1 adult

Cheapflights Tip: The best prices from Panama City Tocumen Intl to Mexico City Benito Juarez are usually found in February or March, booked 77 days in advance, depart on a Wednesday or Tuesday and return on a Monday

Cheap flight deals from Panama City to Mexico City

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Mexico City (MEX). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 30 April 2025.

Round-trip from

£253

One-way from

£123

Popular in

July

Cheapest in

February

Average price

£311
Copa Airlines
  • Copa Airlines
  • 20/6-28/6
  • Nonstop
  • 7h 46m total
  • Panama City to Mexico City
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Avianca
  • Avianca
  • 31/5
  • 1 total stop
  • 10h 40m total
  • Panama City to Mexico City
Search Deals
Highest demand for flights based on searches. 8% potential increase in price (£22 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease (£3 potential savings vs. average return price).
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Average for round-trip flights in April 2025
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Find flight deals from Panama City to Mexico City

Cheapest flights from Panama City to Mexico City
Explore the most affordable flight options available from Panama City to Mexico City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 30 April 2025.

Fri 20/619:03PTY - MEX
Nonstop4h 02mCopa Airlines
Sat 28/601:40MEX - PTY
Nonstop3h 44mCopa Airlines
Deal found 29/4£253
Thu 19/617:25PTY - MEX
1 stop10h 40mAvianca
Wed 25/605:00MEX - PTY
2 stops10h 30mAvianca
Deal found 29/4£289
Sun 31/810:00PTY - MEX
1 stop8h 50mUnited Airlines
Mon 8/909:35MEX - PTY
1 stop8h 02mUnited Airlines
Deal found 29/4£858

Cheapflights Fare Finder

Customise your flight search to find flights from Panama City to Mexico City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 30 April 2025.
Use the filters below to find and compare flights from Panama City to Mexico City that are best for you.

Fly from

Panama City

Fly to

Mexico City

Route

Depart

Return

Price

Panama CityMexico City

PTY - MEX

PTYMEX

Panama City Tocumen Intl

Fri 20/6

19:03-22:05

Nonstop4h 02m

Mexico City Benito Juarez

Sat 28/6

01:40-06:24

Nonstop3h 44m

£253

Panama CityMexico City

PTY - MEX

PTYMEX

Panama City Tocumen Intl

Thu 19/6

17:25-03:05

1 stop10h 40m

Mexico City Benito Juarez

Wed 25/6

05:00-16:30

2 stops10h 30m

£289

Panama CityMexico City

PTY - MEX

PTYMEX

Panama City Tocumen Intl

Sun 31/8

10:00-17:50

1 stop8h 50m

Mexico City Benito Juarez

Mon 8/9

09:35-18:37

1 stop8h 02m

£858

Panama CityMexico City

PTY - MEX

PTYMEX

Panama City Tocumen Intl

Sat 31/5

17:25-03:05

1 stop10h 40m

£123

Panama CityMexico City

PTY - MEX

PTYMEX

Panama City Tocumen Intl

Tue 13/5

15:40-09:55

2 stops19h 15m

£154

Panama CityMexico City

PTY - MEX

PTYMEX

Panama City Tocumen Intl

Tue 13/5

19:10-22:05

Nonstop3h 55m

£351

Flights are sorted by cheapest return flights first.

Deals found on 30/4

Best time to book a flight from Panama City to Mexico City

Have a flexible travel schedule? Discover the best time to fly to Mexico City from Panama City with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Mexico City

How far ahead should I book a flight from Panama City to Mexico City?

Use this chart to determine the optimal time to book a return flight from Panama City to Mexico City. Price data was last updated on 25 April 2025.

The price you pay for your flight from Panama City to Mexico City may vary depending on when you book. For the best chance of a lower fare, look to book 38 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Panama City to Mexico City?

Currently, April is the cheapest month in which you can book a flight from Panama City to Mexico City (average of £791). Flying from Panama City to Mexico City in July is currently the most expensive (average of £1,261). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to MEX?

Find hourly flight availability from Panama City to Mexico City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 30 April 2025.

It’s optimal to fly from Panama City to Mexico City at midday. By choosing this option you can save up to 7% on the cost of your flight, compared to a flight in the morning.

Rainfall in Mexico City by month

Plan your trip to Mexico City by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Mexico City ranges from 0.0 - 120.0 inches per month. July is typically the wettest month, when rainfall can reach 120.0 mm. January is typically the driest time to visit Mexico City when rainfall is around 0.0 mm.

Temperature in Mexico City by month

Plan your trip to Mexico City by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Mexico City, use this chart to help with planning. For those seeking warmer temperatures, May is the ideal time of year to visit, when temperatures reach an average of 19.0 C. Travellers hoping to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 13.0 C).

Reviews of airlines servicing Mexico City

Get insights into the airlines that provide service to Mexico City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mexico City. Reviews last updated 30 April 2025.
Copa Airlines
7.5
Good
1,414 reviews
Check prices

Entertainment

6.8

Comfort

7.4

Overall

7.5

Boarding

7.8

Crew

8.1

Food

6.8

Reviews

1 / 20
4.0
Okay

Anonymous,Mar 2025

PTY - JFK

There was no chance for me to choose a seat even if I were willing to pay extra for it when I was doing the check-in on line. My seats were the last row on the plane and they didn't have enough food to give me. I had to eat what was left after everybody else had their choice of food. This is unacceptable. Everyone should have a choice. I paid money just like everybody else. Never had this happened on any other airlines even if my seats were last row on the plane.
Copa Airlines
7.5
Good
1,414 reviews
Copa Airlines
7.5
Good
1,414 reviews
Check prices

Entertainment

6.8

Comfort

7.4

Overall

7.5

Boarding

7.8

Crew

8.1

Food

6.8

Reviews

1 / 20
4.0
Okay

Anonymous,Mar 2025

PTY - JFK

There was no chance for me to choose a seat even if I were willing to pay extra for it when I was doing the check-in on line. My seats were the last row on the plane and they didn't have enough food to give me. I had to eat what was left after everybody else had their choice of food. This is unacceptable. Everyone should have a choice. I paid money just like everybody else. Never had this happened on any other airlines even if my seats were last row on the plane.
United Airlines
7.4
Good
8,696 reviews
Copa Airlines
7.5
Good
1,414 reviews
Check prices

Entertainment

6.8

Comfort

7.4

Overall

7.5

Boarding

7.8

Crew

8.1

Food

6.8

Reviews

1 / 20
4.0
Okay

Anonymous,Mar 2025

PTY - JFK

There was no chance for me to choose a seat even if I were willing to pay extra for it when I was doing the check-in on line. My seats were the last row on the plane and they didn't have enough food to give me. I had to eat what was left after everybody else had their choice of food. This is unacceptable. Everyone should have a choice. I paid money just like everybody else. Never had this happened on any other airlines even if my seats were last row on the plane.
Avianca
6.7
Okay
2,317 reviews
Copa Airlines
7.5
Good
1,414 reviews
Check prices

Entertainment

6.8

Comfort

7.4

Overall

7.5

Boarding

7.8

Crew

8.1

Food

6.8

Reviews

1 / 20
4.0
Okay

Anonymous,Mar 2025

PTY - JFK

There was no chance for me to choose a seat even if I were willing to pay extra for it when I was doing the check-in on line. My seats were the last row on the plane and they didn't have enough food to give me. I had to eat what was left after everybody else had their choice of food. This is unacceptable. Everyone should have a choice. I paid money just like everybody else. Never had this happened on any other airlines even if my seats were last row on the plane.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Mexico City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Panama City to Mexico City?

    You will need to book a flight from Panama City Tocumen Intl to Mexico City Benito Juarez if you want to fly from Panama City to Mexico City. At least 1 airline has flights from Tocumen Intl (PTY) to Benito Juarez (MEX) on a regular basis. There are 3 flights to Mexico City from the Panama City airport per day. If you manage to book one that is nonstop, then you can expect the flight time from PTY to MEX to be around 3h 55m.

  • How popular is this Panama City to Mexico City flight route?

    The Panama City Tocumen Intl to Mexico City Benito Juarez flight path was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines flying from Panama City to Mexico City round-trip?

    Flying on Copa Airlines is currently your cheapest option to Mexico City, with prices starting at £253. Additional return tickets that might be worth considering are offered by Avianca and United Airlines, with the lowest prices starting at £289 and £858, respectively. You may be able to fly from Panama City to Mexico City for 26% less than the average price by searching for these airlines.

  • Can I find deals for flights from Panama City to Mexico City that include hotel bookings?

    Yes. In addition to deals on Panama City to Mexico City flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Mexico City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Mexico City.

  • Can I find deals for business class flights from Panama City to Mexico City?

    Yes. Cheapflights offers flight deals from Panama City to Mexico City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Mexico City?

    Currently, April is the cheapest month in which you can book a flight from Panama City to Mexico City (average of £791). Flying from Panama City to Mexico City in July is currently the most expensive (average of £1,261). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top airline flying from Panama City to Mexico City

Discover the top airline that operate flights from Panama City to Mexico City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 30 April 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest£278Average£329FlexibilityNo cancel feeOn-time70%
Search Copa Airlines flights

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Why should you use Cheapflights to find cheap flight tickets from Panama City to Mexico City?

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Can Cheapflights find flights from Panama City to Mexico City with no change fees?

Yes! Cheapflights helps users easily find flights from Panama City to Mexico City with no change fees.

Can Cheapflights notify me if prices for flights from Panama City to Mexico City become cheaper?

Yes, Cheapflights has a feature called Price Alert, which notifies users when flight prices change. Track prices for your flight to Mexico City from Panama City today and book when prices fit your budget.

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