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Cheap flights from London Heathrow Airport to Panama from £393

LHR — PTY
28 Oct — 4 Nov1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Heathrow to Panama

Enter your travel dates to find the best prices.

Cheapest flights from Heathrow to Panama

Wed 11/1121:35 -
1 stop22h 40m
Wed 25/1116:10 -
1 stop17h 25m
Deal found 25/9£550
Tue 3/1121:35 -
1 stop16h 35m
Thu 12/1116:10 -
1 stop17h 25m
Deal found 28/9£551
Mon 2/1121:35 -
1 stop16h 35m
Mon 9/1116:10 -
1 stop17h 25m
Deal found 24/9£553
Sun 1/1121:35 -
1 stop16h 35m
Sat 14/1116:10 -
1 stop17h 25m
Deal found 26/9£566
Mon 2/1121:35 -
1 stop22h 40m
Wed 18/1110:05 -
1 stop23h 30m
Deal found 28/9£584
Thu 12/1121:35 -
2 stops33h 35m
Thu 19/1110:05 -
1 stop23h 30m
Deal found 28/9£584
Mon 2/1121:35 -
1 stop24h 40m
Sun 15/1116:10 -
1 stop17h 25m
Deal found 24/9£587
Tue 3/1121:35 -
1 stop15h 24m
Thu 12/1117:51 -
1 stop15h 44m
Deal found 28/9£1,089
Thu 5/1121:35 -
1 stop15h 24m
Thu 26/1117:51 -
1 stop15h 44m
Deal found 28/9£1,108
Mon 23/1121:35 -
1 stop20h 19m
Fri 27/1116:11 -
1 stop17h 24m
Deal found 28/9£1,194
Sun 22/1121:35 -
1 stop15h 24m
Fri 27/1116:11 -
1 stop17h 24m
Deal found 28/9£1,225
Tue 1/1221:35 -
1 stop15h 24m
Sat 5/1212:31 -
1 stop21h 04m
Deal found 28/9£1,323

Find flight deals from Heathrow to Panama

Round-trip from

£550

One-way from

£393

Popular in

December

Cheapest in

November

Average price

£679
Avianca
  • Avianca
  • 11/11-25/11
  • 2 total stops
  • 40h 05m total
  • London to Panama
Search Deals
10/3-31/12
  • 10/3-31/12
  • 2 total stops
  • 33h 30m total
  • London to Panama
Search Deals
Highest demand for flights based on searches. 2% potential increase in price (£16 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease (£13 potential savings vs. average return price).
Search Deals
Average for round-trip flights in September 2026
Search Deals

Cheapflights Fare Finder

 
Use the filters below to find and compare flights from London Heathrow Airport to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

LondonPanama City

LHR London Heathrow - PTY Panama City Tocumen Intl

LHRPTY

London Heathrow

Wed 10/3

06:20-20:20

1 stop19h 00m

Panama City Tocumen Intl

Wed 31/12

00:00-06:00

Nonstop0h 00m

£448

LondonPanama City

LHR London Heathrow - PTY Panama City Tocumen Intl

LHRPTY

London Heathrow

Sun 8/11

21:35-15:15

1 stop22h 40m

Panama City Tocumen Intl

Wed 31/12

00:00-06:00

Nonstop0h 00m

£462

LondonPanama City

LHR London Heathrow - PTY Panama City Tocumen Intl

LHRPTY

London Heathrow

Tue 27/10

21:35-17:15

1 stop24h 40m

Panama City Tocumen Intl

Wed 31/12

00:00-06:00

Nonstop0h 00m

£466

LondonPanama City

LHR London Heathrow - PTY Panama City Tocumen Intl

LHRPTY

London Heathrow

Fri 20/11

15:15-16:01

2 stops53h 46m

Panama City Tocumen Intl

Wed 31/12

00:00-06:00

Nonstop0h 00m

£492

LondonPanama City

LHR London Heathrow - PTY Panama City Tocumen Intl

LHRPTY

London Heathrow

Tue 17/11

20:05-16:01

2 stops48h 56m

Panama City Tocumen Intl

Wed 31/12

00:00-06:00

Nonstop0h 00m

£542

LondonPanama City

LHR London Heathrow - BLB Panama City Panamá Pacifico

LHRBLB

London Heathrow

Wed 10/3

19:20-07:59

3 stops41h 39m

Panama City Panamá Pacifico

Wed 31/12

00:00-06:00

Nonstop0h 00m

£575

LondonPanama City

LHR London Heathrow - BLB Panama City Panamá Pacifico

LHRBLB

London Heathrow

Sat 6/2

19:40-07:59

3 stops41h 19m

Panama City Panamá Pacifico

Wed 31/12

00:00-06:00

Nonstop0h 00m

£581
Fastest return journey

LondonPanama City

LHR London Heathrow - PTY Panama City Tocumen Intl

LHRPTY

London Heathrow

Fri 4/12

10:00-19:55

1 stop14h 55m

Panama City Tocumen Intl

Wed 31/12

00:00-06:00

Nonstop0h 00m

£593

LondonPanama City

LHR London Heathrow - BLB Panama City Panamá Pacifico

LHRBLB

London Heathrow

Tue 17/11

09:15-19:16

3 stops39h 01m

Panama City Panamá Pacifico

Wed 31/12

00:00-06:00

Nonstop0h 00m

£600

LondonPanama City

LHR London Heathrow - PTY Panama City Tocumen Intl

LHRPTY

London Heathrow

Tue 27/10

22:05-19:45

3 stops26h 40m

Panama City Tocumen Intl

Wed 31/12

00:00-06:00

Nonstop0h 00m

£649

Flights are sorted by cheapest return flights first.

Deals found on 28/9

Showing 1-10 of 44 resultsSorted by cheapest first
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Best time to book a flight from Heathrow to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Heathrow with our price prediction graph.
Estimated return price

Cheapflights Insights

Everything you need to know about your flight from London Heathrow Airport to Panama

What is the cheapest month to book a flight from London Heathrow Airport to Panama?

Currently, May is the cheapest month in which you can book a flight from London Heathrow Airport to Panama (average of £556). Flying from London Heathrow Airport to Panama in December is currently the most expensive (average of £954). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How far ahead should I book a flight from London Heathrow Airport to Panama?

The price you pay for your flight from London Heathrow Airport to Panama may vary depending on when you book. For the best chance of a lower fare, look to book 37 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

Reviews of airlines servicing Panama

Get a feel of what it's like to fly with KLM,Air France, andUnited Airlines from London Heathrow Airport to Panama by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7.8
Good
1,577 reviews
Check prices

Overall

7.8

Boarding

7.8

Comfort

7.7

Entertainment

7.2

Crew

8.4

Food

7.3

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
KLM
7.8
Good
1,577 reviews
KLM
7.8
Good
1,577 reviews
Check prices

Overall

7.8

Boarding

7.8

Comfort

7.7

Entertainment

7.2

Crew

8.4

Food

7.3

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
Air France
7.5
Good
1,650 reviews
KLM
7.8
Good
1,577 reviews
Check prices

Overall

7.8

Boarding

7.8

Comfort

7.7

Entertainment

7.2

Crew

8.4

Food

7.3

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
United Airlines
7.4
Good
10,251 reviews
KLM
7.8
Good
1,577 reviews
Check prices

Overall

7.8

Boarding

7.8

Comfort

7.7

Entertainment

7.2

Crew

8.4

Food

7.3

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
Lufthansa
6.8
Okay
8,248 reviews
KLM
7.8
Good
1,577 reviews
Check prices

Overall

7.8

Boarding

7.8

Comfort

7.7

Entertainment

7.2

Crew

8.4

Food

7.3

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
Avianca
6.5
Okay
2,554 reviews
KLM
7.8
Good
1,577 reviews
Check prices

Overall

7.8

Boarding

7.8

Comfort

7.7

Entertainment

7.2

Crew

8.4

Food

7.3

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas

Related info for your journey

  • How long is the flight from London Heathrow Airport to Panama?

    United Airlines can get you from London Heathrow Airport to Panama in just under 18h 41m. Your travel time can differ by up to . Airlines will cover a distance of 5249 mi.

  • Can I find deals for flights from Heathrow to Panama that include hotel bookings?

    Yes. In addition to deals on Heathrow to Panama flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Heathrow to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Heathrow to Panama.

  • Can I find deals for business class flights from Heathrow to Panama?

    Yes. Cheapflights offers flight deals from Heathrow to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from London Heathrow Airport to Panama?

    Currently, May is the cheapest month in which you can book a flight from London Heathrow Airport to Panama (average of £556). Flying from London Heathrow Airport to Panama in December is currently the most expensive (average of £954). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 7 airlines flying from Heathrow to Panama

AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest£395Average£604FlexibilityNo cancel feeOn-time71%
Search Avianca flights
IberiaCheapest£570Average£881FlexibilityNo cancel feeOn-time77%
Search Iberia flights
Air FranceCheapest£604Average£850FlexibilityNo cancel feeOn-time77%
Search Air France flights
LufthansaCheapest£639Average£770FlexibilityNo cancel feeOn-time76%
Search Lufthansa flights
KLMCheapest£646Average£927FlexibilityNo cancel feeOn-time75%
Search KLM flights
United AirlinesCheapest£647Average£789FlexibilityNo cancel feeOn-time69%
Search United Airlines flights
British AirwaysCheapest£647Average£861FlexibilityNo cancel feeOn-time70%
Search British Airways flights

Fly with Cheapflights

How does Cheapflights help users find flights from Heathrow to Panama?

Deals for Heathrow to Panama flights are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose better, like price, airport, cabin class, and plenty of other options.

Why should you use Cheapflights to find cheap flight tickets from Heathrow to Panama?

Millions of users choose and trust Cheapflights to book the best flight deals from Heathrow to Panama for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.

Can Cheapflights find flights from Heathrow to Panama with no change fees?

Certainly. Search results for flights to Panama from Heathrow shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Heathrow to Panama become cheaper?

Yes! Start tracking prices for Heathrow to Panama flights today and get alerted whenever prices for these flights change. To access this feature, click the bell icon next to the flight deals above, which will prompt you for a valid email address to receive your alerts.

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