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Cheap flights from London Heathrow Airport to Panama from £349

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 16/6. Fares are subject to change and may not be available on all flights or dates of travel.
LHR — PTY
21 Feb — 28 Feb1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Heathrow to Panama

Enter your travel dates to find the best prices.

Cheapest flights from Heathrow to Panama
Explore the most affordable flight options available from Heathrow to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 22 January 2026.

Mon 26/121:40
LHR
-
PTY
1 stop16h 10m
Avianca
Mon 9/219:50
PTY
-
LHR
2 stops37h 45m
Avianca
Deal found 20/1£577
Mon 26/121:40
LHR
-
PTY
1 stop21h 20m
Avianca
Mon 16/219:50
PTY
-
LHR
2 stops37h 45m
Avianca
Deal found 21/1£578
Tue 16/622:05
LHR
-
PTY
2 stops33h 50m
Avianca
Sun 12/705:30
PTY
-
LHR
2 stops28h 05m
Avianca
Deal found 20/1£579
Wed 1/422:05
LHR
-
PTY
1 stop24h 25m
Avianca
Tue 14/417:25
PTY
-
LHR
1 stop16h 10m
Avianca
Deal found 20/1£581
Tue 16/606:15
LHR
-
PTY
1 stop19h 30m
Air France
Sun 12/721:55
PTY
-
LHR
1 stop14h 40m
Air France
Deal found 21/1£585
Wed 11/320:50
LHR
-
PTY
2 stops33h 10m
Multiple Airlines
Mon 16/302:55
PTY
-
LHR
2 stops36h 10m
Multiple Airlines
Deal found 21/1£589
Mon 2/321:40
LHR
-
PTY
1 stop16h 10m
Avianca
Thu 12/317:50
PTY
-
LHR
1 stop15h 45m
Avianca
Deal found 20/1£593
Fri 6/321:40
LHR
-
PTY
1 stop21h 20m
Avianca
Fri 13/314:55
PTY
-
LHR
1 stop18h 40m
Avianca
Deal found 19/1£593
Mon 20/422:05
LHR
-
PTY
1 stop29h 05m
Avianca
Sun 26/405:30
PTY
-
LHR
2 stops28h 05m
Avianca
Deal found 19/1£595

Find flight deals from Heathrow to Panama

Keep the following information in mind while searching for Heathrow to Panama flight deals. Data was last updated 22 January 2026.

Round-trip from

£579

One-way from

£349

Popular in

December

Cheapest in

June

Average price

£636
Avianca
  • Avianca
  • 16/6-12/7
  • 4 total stops
  • 61h 55m total
  • London to Panama
Search Deals
16/6
  • 16/6
  • 2 total stops
  • 26h 30m total
  • London to Panama
Search Deals
Highest demand for flights based on searches. 6% potential increase in price (£32 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease (£15 potential savings vs. average return price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Heathrow to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 22 January 2026.
Use the filters below to find and compare flights from London Heathrow Airport to Panama that are best for you.

Fly from

Heathrow

Fly to

Panama

Route

Depart

Return

Price

LondonPanama City

LHR - PTY

LHRPTY

London Heathrow

Mon 9/3

21:40-08:50

1 stop16h 10m

Panama City Tocumen Intl

Mon 16/3

14:55-14:35

1 stop18h 40m

£594

LondonPanama City

LHR - PTY

LHRPTY

London Heathrow

Fri 13/3

21:40-18:55

2 stops26h 15m

Panama City Tocumen Intl

Thu 26/3

14:55-14:35

1 stop18h 40m

£595

LondonPanama City

LHR - PTY

LHRPTY

London Heathrow

Mon 20/4

22:05-08:55

1 stop16h 50m

Panama City Tocumen Intl

Sun 26/4

11:05-15:35

1 stop22h 30m

£596

LondonPanama City

LHR - PTY

LHRPTY

London Heathrow

Thu 12/3

21:40-08:50

1 stop16h 10m

Panama City Tocumen Intl

Tue 24/3

17:50-14:35

1 stop15h 45m

£622

LondonPanama City

LHR - PTY

LHRPTY

London Heathrow

Thu 12/3

21:40-14:00

1 stop21h 20m

Panama City Tocumen Intl

Thu 26/3

14:55-14:35

1 stop18h 40m

£622

LondonPanama City

LHR - PTY

LHRPTY

London Heathrow

Sat 14/3

21:40-08:50

1 stop16h 10m

Panama City Tocumen Intl

Tue 24/3

17:50-14:35

1 stop15h 45m

£622

LondonPanama City

LHR - PTY

LHRPTY

London Heathrow

Sat 14/3

21:40-14:00

1 stop21h 20m

Panama City Tocumen Intl

Thu 26/3

14:55-14:35

1 stop18h 40m

£622

LondonPanama City

LHR - PTY

LHRPTY

London Heathrow

Sat 14/3

06:15-16:45

1 stop15h 30m

Panama City Tocumen Intl

Sat 28/3

15:10-11:35

1 stop15h 25m

£629

LondonPanama City

LHR - PTY

LHRPTY

London Heathrow

Fri 13/3

21:40-18:55

2 stops26h 15m

Panama City Tocumen Intl

Tue 24/3

14:55-14:35

1 stop18h 40m

£631

LondonPanama City

LHR - PTY

LHRPTY

London Heathrow

Tue 16/6

20:00-16:30

2 stops26h 30m

£349

Flights are sorted by cheapest return flights first.

Deals found on 21/1

Showing 1-10 of 19 results
1
2

Best time to book a flight from Heathrow to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Heathrow with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from London Heathrow Airport to Panama

What is the cheapest month to book a flight from London Heathrow Airport to Panama?

Currently, May is the cheapest month in which you can book a flight from London Heathrow Airport to Panama (average of £497). Flying from London Heathrow Airport to Panama in December is currently the most expensive (average of £649). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated 22 January 2026.
Get a feel of what it's like to fly with KLM, Air France, andUnited Airlines from London Heathrow Airport to Panama by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7.7
Good
1,442 reviews
Check prices

Overall

7.7

Crew

8.4

Boarding

7.8

Comfort

7.6

Entertainment

7.1

Food

7.3

Reviews

1 / 20
10.0
Excellent

Snapyou,Jan 2026

TPA - LHR

Flight operated by Virgin Atlantic - usual high standard service by Virgin.
KLM
7.7
Good
1,442 reviews
KLM
7.7
Good
1,442 reviews
Check prices

Overall

7.7

Crew

8.4

Boarding

7.8

Comfort

7.6

Entertainment

7.1

Food

7.3

Reviews

1 / 20
10.0
Excellent

Snapyou,Jan 2026

TPA - LHR

Flight operated by Virgin Atlantic - usual high standard service by Virgin.
Air France
7.4
Good
1,523 reviews
KLM
7.7
Good
1,442 reviews
Check prices

Overall

7.7

Crew

8.4

Boarding

7.8

Comfort

7.6

Entertainment

7.1

Food

7.3

Reviews

1 / 20
10.0
Excellent

Snapyou,Jan 2026

TPA - LHR

Flight operated by Virgin Atlantic - usual high standard service by Virgin.
United Airlines
7.4
Good
9,191 reviews
KLM
7.7
Good
1,442 reviews
Check prices

Overall

7.7

Crew

8.4

Boarding

7.8

Comfort

7.6

Entertainment

7.1

Food

7.3

Reviews

1 / 20
10.0
Excellent

Snapyou,Jan 2026

TPA - LHR

Flight operated by Virgin Atlantic - usual high standard service by Virgin.
Lufthansa
6.8
Okay
7,738 reviews
KLM
7.7
Good
1,442 reviews
Check prices

Overall

7.7

Crew

8.4

Boarding

7.8

Comfort

7.6

Entertainment

7.1

Food

7.3

Reviews

1 / 20
10.0
Excellent

Snapyou,Jan 2026

TPA - LHR

Flight operated by Virgin Atlantic - usual high standard service by Virgin.
Avianca
6.6
Okay
2,496 reviews
KLM
7.7
Good
1,442 reviews
Check prices

Overall

7.7

Crew

8.4

Boarding

7.8

Comfort

7.6

Entertainment

7.1

Food

7.3

Reviews

1 / 20
10.0
Excellent

Snapyou,Jan 2026

TPA - LHR

Flight operated by Virgin Atlantic - usual high standard service by Virgin.

Related info for your journey

Find useful and relevant information for your journey from Heathrow to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from London Heathrow Airport to Panama?

    Avianca can get you from London Heathrow Airport to Panama in just under 16h 10m. Your travel time can differ by up to . Airlines will cover a distance of 5249 mi.

  • Can I find deals for flights from Heathrow to Panama that include hotel bookings?

    Yes. In addition to deals on Heathrow to Panama flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Heathrow to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Heathrow to Panama.

  • Can I find deals for business class flights from Heathrow to Panama?

    Yes. Cheapflights offers flight deals from Heathrow to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from London Heathrow Airport to Panama?

    Currently, May is the cheapest month in which you can book a flight from London Heathrow Airport to Panama (average of £497). Flying from London Heathrow Airport to Panama in December is currently the most expensive (average of £649). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Heathrow to Panama

See prices for flight routes from nearby airports that may be better suited for you.
Heathrow to San José flights
Gatwick to San José flights
London City to San José flights
Stansted to San José flights
Heathrow to Panama City flights
Heathrow to Guatemala City flights
Heathrow to Philip S.W.Goldson flights
Gatwick to Guatemala City flights
Luton to San José flights
Gatwick to Panama City flights
London City to Guatemala City flights
London City to Panama City flights
Stansted to Panama City flights
Gatwick to Philip S.W.Goldson flights
Heathrow to Managua flights
Heathrow to Liberia flights
London City to Managua flights
Gatwick to Managua flights
Luton to Panama City flights
Heathrow to San Salvador flights
Stansted to Guatemala City flights
Gatwick to Liberia flights
Gatwick to San Salvador flights
London City to Liberia flights
Heathrow to San Pedro Sula flights
London City to San Salvador flights
Heathrow to Coxen Hole flights
Gatwick to San Pedro Sula flights
London City to San Pedro Sula flights
Stansted to Managua flights
Stansted to San Salvador flights
Gatwick to Tegucigalpa flights
London City to Tegucigalpa flights
Heathrow to Tegucigalpa flights

Top 8 airlines flying from Heathrow to Panama

Discover the top 8 airlines that operate flights from Heathrow to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 22 January 2026.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest£518Average£593FlexibilityNo cancel feeOn-time71%
Search Avianca flights
LufthansaCheapest£550Average£622FlexibilityNo cancel feeOn-time76%
Search Lufthansa flights
Air FranceCheapest£554Average£703FlexibilityNo cancel feeOn-time77%
Search Air France flights
KLMCheapest£560Average£750FlexibilityNo cancel feeOn-time75%
Search KLM flights
United AirlinesCheapest£588Average£690FlexibilityNo cancel feeOn-time69%
Search United Airlines flights
IberiaCheapest£611Average£976FlexibilityNo cancel feeOn-time77%
Search Iberia flights
British AirwaysCheapest£629Average£806FlexibilityNo cancel feeOn-time70%
Search British Airways flights
Turkish AirlinesCheapest£644Average£899FlexibilityNo cancel feeOn-time77%
Search Turkish Airlines flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Heathrow to Panama?

Deals for Heathrow to Panama flights are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose better, like price, airport, cabin class, and plenty of other options.

Why should you use Cheapflights to find cheap flight tickets from Heathrow to Panama?

Millions of users choose and trust Cheapflights to book the best flight deals from Heathrow to Panama for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.

Can Cheapflights find flights from Heathrow to Panama with no change fees?

Certainly. Search results for flights to Panama from Heathrow shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Heathrow to Panama become cheaper?

Yes! Start tracking prices for Heathrow to Panama flights today and get alerted whenever prices for these flights change. To access this feature, click the bell icon next to the flight deals above, which will prompt you for a valid email address to receive your alerts.

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