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Cheap flights from London Luton Airport to Panama from £349

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/12. Fares are subject to change and may not be available on all flights or dates of travel.
LTN — PTY
30 Nov — 7 Dec1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Luton to Panama

Keep the following information in mind while searching for Luton to Panama flight deals. Data was last updated 31 October 2025.

Round-trip from

£659

One-way from

£349

Popular in

December

Cheapest in

June

Average price

£701
7/1-18/3
  • 7/1-18/3
  • 4 total stops
  • 53h 40m total
  • London to Panama
Search Deals
5/12
  • 5/12
  • 2 total stops
  • 28h 00m total
  • London to Panama
Search Deals
Highest demand for flights based on searches. 7% potential increase in price (£39 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease (£15 potential savings vs. average return price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Find flight deals from Luton to Panama

Enter your travel dates to find the best prices.

Cheapest flights from Luton to Panama
Explore the most affordable flight options available from Luton to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 31 October 2025.

Tue 25/1114:25LTN - PTY
2 stops34h 25mMultiple Airlines
Thu 27/1119:05PTY - LTN
2 stops18h 05mMultiple Airlines
Deal found 29/10£691
Mon 17/1106:25LTN - PTY
2 stops31h 25mMultiple Airlines
Sun 30/1109:45PTY - LTN
2 stops21h 15mMultiple Airlines
Deal found 29/10£821
Sun 7/1220:50LTN - PTY
2 stops28h 00mMultiple Airlines
Sat 13/1202:55PTY - LTN
3 stops29h 45mMultiple Airlines
Deal found 30/10£845
Fri 14/1106:35LTN - PTY
2 stops39h 30mMultiple Airlines
Fri 21/1121:30PTY - LTN
2 stops43h 35mMultiple Airlines
Deal found 29/10£933
Wed 12/1107:30LTN - PTY
3 stops39h 27mMultiple Airlines
Thu 20/1119:05PTY - LTN
2 stops20h 55mMultiple Airlines
Deal found 30/10£938
Tue 4/1107:10LTN - PTY
1 stop18h 00mMultiple Airlines
Tue 11/1118:45PTY - LTN
2 stops18h 05mMultiple Airlines
Deal found 30/10£944
Fri 28/1107:00LTN - PTY
1 stop18h 10mMultiple Airlines
Sun 7/1222:20PTY - LTN
1 stop13h 15mMultiple Airlines
Deal found 29/10£954
Mon 10/1107:50LTN - PTY
2 stops27h 49mMultiple Airlines
Mon 17/1111:55PTY - LTN
2 stops27h 15mMultiple Airlines
Deal found 29/10£999
Sat 29/1106:15LTN - PTY
2 stops18h 30mMultiple Airlines
Sat 6/1221:30PTY - LTN
2 stops17h 15mMultiple Airlines
Deal found 30/10£1,022

Cheapflights Fare Finder

 
Customise your flight search to find flights from Luton to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 31 October 2025.
Use the filters below to find and compare flights from London Luton Airport to Panama that are best for you.

Fly from

Luton

Fly to

Panama

Route

Depart

Return

Price

LondonPanama City

LTN - PTY

LTNPTY

London Luton

Wed 7/1

15:05-19:45

2 stops33h 40m

Panama City Tocumen Intl

Wed 18/3

21:30-22:30

2 stops20h 00m

£659

LondonPanama City

LTN - PTY

LTNPTY

London Luton

Tue 25/11

14:25-19:50

2 stops34h 25m

Panama City Tocumen Intl

Thu 27/11

19:05-18:10

2 stops18h 05m

£691

LondonPanama City

LTN - PTY

LTNPTY

London Luton

Sun 7/12

20:50-19:50

2 stops28h 00m

Panama City Tocumen Intl

Sat 13/12

02:55-13:40

3 stops29h 45m

£845

LondonPanama City

LTN - PTY

LTNPTY

London Luton

Sat 14/2

16:00-19:45

2 stops32h 45m

Panama City Tocumen Intl

Sat 21/2

21:30-22:45

2 stops20h 15m

£850

LondonPanama City

LTN - PTY

LTNPTY

London Luton

Fri 14/11

06:35-17:05

2 stops39h 30m

Panama City Tocumen Intl

Fri 21/11

21:30-22:05

2 stops43h 35m

£933

LondonPanama City

LTN - PTY

LTNPTY

London Luton

Wed 12/11

07:30-17:57

3 stops39h 27m

Panama City Tocumen Intl

Thu 20/11

19:05-21:00

2 stops20h 55m

£938

LondonPanama City

LTN - PTY

LTNPTY

London Luton

Mon 10/11

07:50-06:39

2 stops27h 49m

Panama City Tocumen Intl

Mon 17/11

11:55-20:10

2 stops27h 15m

£999

LondonPanama City

LTN - PTY

LTNPTY

London Luton

Sat 29/11

06:15-19:45

2 stops18h 30m

Panama City Tocumen Intl

Sat 6/12

21:30-19:45

2 stops17h 15m

£1,022

LondonPanama City

LTN - PTY

LTNPTY

London Luton

Sun 1/3

17:15-19:45

1 stop31h 30m

Panama City Tocumen Intl

Sun 15/3

21:30-12:15

1 stop33h 45m

£1,051

LondonPanama City

LTN - PTY

LTNPTY

London Luton

Sun 25/1

21:40-19:50

2 stops27h 10m

Panama City Tocumen Intl

Sun 1/2

21:30-20:55

2 stops18h 25m

£1,078

Flights are sorted by cheapest return flights first.

Deals found on 29/10

Showing 1-10 of 19 results
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Best time to book a flight from Luton to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Luton with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from London Luton Airport to Panama
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Related info for your journey

Find useful and relevant information for your journey from Luton to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • Can I find deals for flights from Luton to Panama that include hotel bookings?

    Yes. In addition to deals on Luton to Panama flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Luton to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Luton to Panama.

  • Can I find deals for business class flights from Luton to Panama?

    Yes. Cheapflights offers flight deals from Luton to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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Alternative routes for Luton to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Need flexible booking options for your flight to Panama from Luton? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

Can Cheapflights notify me if prices for flights from Luton to Panama become cheaper?

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