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Cheap flights from London Luton Airport to Panama from £349

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 25/11. Fares are subject to change and may not be available on all flights or dates of travel.
LTN — PTY
14 Dec — 21 Dec1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Luton to Panama

Keep the following information in mind while searching for Luton to Panama flight deals. Data was last updated 14 November 2025.

Round-trip from

£750

One-way from

£349

Popular in

December

Cheapest in

June

Average price

£623
17/1-26/1
  • 17/1-26/1
  • 4 total stops
  • 37h 30m total
  • London to Panama
Search Deals
25/11
  • 25/11
  • 2 total stops
  • 28h 00m total
  • London to Panama
Search Deals
Highest demand for flights based on searches. 7% potential increase in price (£41 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease (£17 potential savings vs. average return price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Find flight deals from Luton to Panama

Enter your travel dates to find the best prices.

Cheapest flights from Luton to Panama
Explore the most affordable flight options available from Luton to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 14 November 2025.

Fri 12/1206:10LTN - PTY
3 stops30h 56mMultiple Airlines
Sun 1/212:33PTY - LTN
3 stops26h 22mMultiple Airlines
Deal found 11/11£906
Sun 23/1120:50LTN - PTY
2 stops24h 55mMultiple Airlines
Sun 30/1121:30PTY - LTN
2 stops17h 25mMultiple Airlines
Deal found 13/11£946
Mon 17/1106:15LTN - PTY
1 stop15h 30mMultiple Airlines
Mon 24/1119:05PTY - LTN
2 stops37h 55mMultiple Airlines
Deal found 13/11£961
Sun 7/1207:20LTN - PTY
2 stops17h 25mMultiple Airlines
Wed 10/1210:25PTY - LTN
3 stops28h 00mMultiple Airlines
Deal found 12/11£967
Sat 6/1209:25LTN - PTY
3 stops36h 30mMultiple Airlines
Fri 30/110:25PTY - LTN
3 stops28h 45mMultiple Airlines
Deal found 11/11£990
Tue 9/1207:10LTN - PTY
2 stops29h 56mMultiple Airlines
Tue 16/1218:45PTY - LTN
1 stop23h 25mMultiple Airlines
Deal found 10/11£999
Sun 30/1120:50LTN - PTY
2 stops27h 55mMultiple Airlines
Thu 4/1221:30PTY - LTN
2 stops19h 40mMultiple Airlines
Deal found 13/11£1,040
Mon 29/1206:30LTN - PTY
1 stop15h 00mMultiple Airlines
Sat 24/121:41PTY - LTN
2 stops34h 39mMultiple Airlines
Deal found 11/11£1,058

Cheapflights Fare Finder

 
Customise your flight search to find flights from Luton to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 14 November 2025.
Use the filters below to find and compare flights from London Luton Airport to Panama that are best for you.

Fly from

Luton

Fly to

Panama

Route

Depart

Return

Price

LondonPanama City

LTN - PTY

LTNPTY

London Luton

Tue 20/1

06:25-16:30

1 stop15h 05m

Panama City Tocumen Intl

Tue 3/2

18:45-21:15

1 stop21h 30m

£815

LondonPanama City

LTN - PTY

LTNPTY

London Luton

Thu 22/1

20:40-00:40

2 stops33h 00m

Panama City Tocumen Intl

Thu 5/2

19:05-21:50

2 stops21h 45m

£859

LondonPanama City

LTN - PTY

LTNPTY

London Luton

Sat 17/1

06:15-19:55

1 stop18h 40m

Panama City Tocumen Intl

Mon 26/1

22:05-19:30

1 stop16h 25m

£887

LondonPanama City

LTN - PTY

LTNPTY

London Luton

Sun 23/11

20:50-16:45

2 stops24h 55m

Panama City Tocumen Intl

Sun 30/11

21:30-19:55

2 stops17h 25m

£946

LondonPanama City

LTN - PTY

LTNPTY

London Luton

Sun 7/12

07:20-19:45

2 stops17h 25m

Panama City Tocumen Intl

Wed 10/12

10:25-19:25

3 stops28h 00m

£967

LondonPanama City

LTN - PTY

LTNPTY

London Luton

Sat 6/12

09:25-16:55

3 stops36h 30m

Panama City Tocumen Intl

Fri 30/1

10:25-20:10

3 stops28h 45m

£990

LondonPanama City

LTN - PTY

LTNPTY

London Luton

Tue 9/12

07:10-08:06

2 stops29h 56m

Panama City Tocumen Intl

Tue 16/12

18:45-23:10

1 stop23h 25m

£999

LondonPanama City

LTN - PTY

LTNPTY

London Luton

Wed 4/3

14:40-19:45

1 stop34h 05m

Panama City Tocumen Intl

Tue 24/3

21:30-20:20

1 stop17h 50m

£1,001

LondonPanama City

LTN - PTY

LTNPTY

London Luton

Wed 11/2

14:40-19:45

1 stop34h 05m

Panama City Tocumen Intl

Sat 21/2

21:30-12:00

1 stop33h 30m

£1,021

LondonPanama City

LTN - PTY

LTNPTY

London Luton

Sat 22/11

20:50-19:50

2 stops52h 00m

£363

Flights are sorted by cheapest return flights first.

Deals found on 11/11

Showing 1-10 of 17 results
1
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Best time to book a flight from Luton to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Luton with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from London Luton Airport to Panama
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Luton to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • Can I find deals for flights from Luton to Panama that include hotel bookings?

    Yes. In addition to deals on Luton to Panama flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Luton to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Luton to Panama.

  • Can I find deals for business class flights from Luton to Panama?

    Yes. Cheapflights offers flight deals from Luton to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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Alternative routes for Luton to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Need flexible booking options for your flight to Panama from Luton? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

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