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Cheap flights from Manchester to Santiago de los Caballeros from £364

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 13/10. Fares are subject to change and may not be available on all flights or dates of travel.
MAN — STI
12 Sep — 19 Sep1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Manchester to Santiago de los Caballeros

Enter your travel dates to find the best prices.

Cheapest flights from Manchester to Santiago de los Caballeros
Explore the most affordable flight options available from Manchester to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 13 August 2026.

Wed 25/1108:15 -
1 stop16h 45m
Wed 2/1223:00 -
1 stop15h 35m
Deal found 9/8£771
Wed 25/1107:50 -
2 stops36h 16m
Wed 2/1217:08 -
2 stops19h 12m
Deal found 12/8£840
Mon 21/906:55 -
2 stops36h 20m
Mon 28/915:15 -
2 stops23h 00m
Deal found 8/8£848
Mon 21/914:55 -
1 stop26h 31m
Mon 28/913:55 -
1 stop13h 20m
Deal found 8/8£883
Wed 9/909:20 -
2 stops33h 55m
Tue 15/915:15 -
2 stops25h 20m
Deal found 11/8£888
Wed 9/914:55 -
1 stop32h 04m
Tue 15/913:55 -
1 stop13h 25m
Deal found 11/8£1,034
Sat 26/906:05 -
2 stops38h 07m
Sat 3/1016:23 -
2 stops37h 02m
Deal found 12/8£1,122
Wed 23/906:05 -
2 stops21h 47m
Wed 30/916:23 -
2 stops37h 02m
Deal found 9/8£1,176

Find flight deals from Manchester to Santiago de los Caballeros

Discover tips and strategies to find the most affordable flight options for your journey from Manchester (MAN) to Santiago de los Caballeros (STI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 13 August 2026.

Round-trip from

£771

One-way from

£364
25/11-2/12
  • 25/11-2/12
  • 2 total stops
  • 32h 20m total
  • Manchester to Santiago de los Caballeros
Search Deals
13/10
  • 13/10
  • 2 total stops
  • 28h 45m total
  • Manchester to Santiago de los Caballeros
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Manchester to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 13 August 2026.
Use the filters below to find and compare flights from Manchester to Santiago de los Caballeros that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight
Fastest return journey

ManchesterSantiago de los Caballeros

MAN Manchester - STI Santiago de los Caballeros

MANSTI

Manchester

Wed 25/11

08:15-21:00

1 stop16h 45m

Santiago de los Caballeros

Wed 2/12

23:00-18:35

1 stop15h 35m

£771

ManchesterSantiago de los Caballeros

MAN Manchester - STI Santiago de los Caballeros

MANSTI

Manchester

Wed 25/11

07:50-16:06

2 stops36h 16m

Santiago de los Caballeros

Wed 2/12

17:08-16:20

2 stops19h 12m

£840

ManchesterSantiago de los Caballeros

MAN Manchester - STI Santiago de los Caballeros

MANSTI

Manchester

Mon 21/9

14:55-12:26

2 stops26h 31m

Santiago de los Caballeros

Mon 28/9

13:55-08:15

1 stop13h 20m

£890

ManchesterSantiago de los Caballeros

MAN Manchester - STI Santiago de los Caballeros

MANSTI

Manchester

Wed 9/9

05:50-12:26

2 stops35h 36m

Santiago de los Caballeros

Tue 15/9

13:55-08:20

1 stop13h 25m

£1,041

ManchesterSantiago de los Caballeros

MAN Manchester - STI Santiago de los Caballeros

MANSTI

Manchester

Wed 23/9

06:05-22:52

2 stops21h 47m

Santiago de los Caballeros

Wed 30/9

16:23-10:25

2 stops37h 02m

£1,176

ManchesterSantiago de los Caballeros

MAN Manchester - STI Santiago de los Caballeros

MANSTI

Manchester

Wed 25/11

14:55-00:55

1 stop14h 00m

Santiago de los Caballeros

Wed 2/12

06:40-08:45

2 stops22h 05m

£1,216
Cheapest one-way

ManchesterSantiago de los Caballeros

MAN Manchester - STI Santiago de los Caballeros

MANSTI

Manchester

Thu 29/10

20:50-21:00

2 stops52h 10m

£378

ManchesterSantiago de los Caballeros

MAN Manchester - STI Santiago de los Caballeros

MANSTI

Manchester

Mon 31/8

20:10-19:50

2 stops52h 40m

£387
Fastest single journey

ManchesterSantiago de los Caballeros

MAN Manchester - STI Santiago de los Caballeros

MANSTI

Manchester

Tue 27/10

19:00-21:00

3 stops30h 00m

£405

ManchesterSantiago de los Caballeros

MAN Manchester - STI Santiago de los Caballeros

MANSTI

Manchester

Tue 13/10

13:35-19:50

1 stop35h 15m

£442

Flights are sorted by cheapest return flights first.

Deals found on 12/8

Sorted by cheapest first

Best time to book a flight from Manchester to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from Manchester with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Manchester to Santiago de los Caballeros. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Manchester to Santiago de los Caballeros?

    American Airlines and Delta can get you from Manchester to Santiago de los Caballeros in just under 26h 31m. Your travel time can differ by up to 9h 45m. Airlines will cover a distance of 4258 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Manchester to Santiago de los Caballeros that include hotel bookings?

    Yes. In addition to deals on Manchester to Santiago de los Caballeros flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Manchester to Santiago de los Caballeros?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to Santiago de los Caballeros.

  • Can I find deals for business class flights from Manchester to Santiago de los Caballeros?

    Yes. Cheapflights offers flight deals from Manchester to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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How does Cheapflights help users find flights from Manchester to Santiago de los Caballeros?

Cheapflights goes through 900+ travel sites to look for the best flight deals for flights from Manchester to Santiago de los Caballeros. Too many options? Cheapflights also provides filters for things like airlines, price ranges, and number of stops to help you make a decision easily.

Why should you use Cheapflights to find cheap flight tickets from Manchester to Santiago de los Caballeros?

Cheapflights helps you find that perfect flight to Santiago de los Caballeros from Manchester by searching from hundreds of airlines and agencies you know and love. We are also free to use, in case you were wondering!

Can Cheapflights find flights from Manchester to Santiago de los Caballeros with no change fees?

Yes, we can. To see specific flights from Manchester to Santiago de los Caballeros with no change fees, users can toggle flexible booking options after using the search form above to find flights.

Can Cheapflights notify me if prices for flights from Manchester to Santiago de los Caballeros become cheaper?

Not ready to book yet? You can track prices for flights from Manchester to Santiago de los Caballeros on Cheapflights with our Price Alert feature and get notified when better prices are available.

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