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Cheap flights from Panama City to Santiago

PTY — SCL
14 Nov — 21 Nov1
1 adult
1 adult, Economy

Cheap flight deals from Panama City to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 15 October 2025.

Popular in

January

Cheapest in

May

Average price

£423
Highest demand for flights based on searches. 4% potential increase in price (£13 potential increase over avg. return price).
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Cheapest flight prices on average. 1% potential price decrease (£4 potential savings vs. average return price).
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Average for round-trip flights in October 2025
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Best time to book a flight from Panama City to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Panama City with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Santiago

How far ahead should I book a flight from Panama City to Santiago?

Use this chart to determine the optimal time to book a return flight from Panama City to Santiago. Price data was last updated on 10 October 2025.

To ensure you get the cheapest price possible for a flight from Panama City to Santiago, you should look to book at least 70 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Panama City to Santiago?

Currently, March is the cheapest month in which you can book a flight from Panama City to Santiago (average of £189). Flying from Panama City to Santiago in July is currently the most expensive (average of £255). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to SCL?

Find hourly flight availability from Panama City to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 15 October 2025.

It’s typically best to fly out from Panama City to Santiago in the afternoon. Doing so could potentially save you 46% on the flight price compared to flying at midday, which is usually more expensive.

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated 15 October 2025.
Get a feel of what it's like to fly with Copa Airlines from Panama City to Santiago by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,548 reviews
Check prices

Boarding

7.8

Comfort

7.4

Crew

8.1

Food

6.8

Entertainment

6.8

Overall

7.6

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sept 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Copa Airlines
7.6
Good
1,548 reviews
Copa Airlines
7.6
Good
1,548 reviews
Check prices

Boarding

7.8

Comfort

7.4

Crew

8.1

Food

6.8

Entertainment

6.8

Overall

7.6

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sept 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip

Related info for your journey

Find useful and relevant information for your journey from Panama City to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Panama City to Santiago flight route?

    Within the past month, 2 users have taken a look at flights from Panama City Tocumen Intl to Santiago Arturo Merino Benitez.

  • What is the cheapest airline to fly from Panama City to Santiago round-trip?

    According to our current data, Copa Airlines (£415), offers the cheapest pricing from Panama City to Santiago. Users have found that Copa Airlines is 3% cheaper than the other options available to this destination.

  • What are the most reliable airlines from Panama City to Santiago?

    The top 3 most reliable airlines when flying from Panama City to Santiago are Copa Airlines (88%), Turkish Airlines (87%) and KLM (83%).

  • Can I find deals for flights from Panama City to Santiago that include hotel bookings?

    Yes. In addition to deals on Panama City to Santiago flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Santiago.

  • Can I find deals for business class flights from Panama City to Santiago?

    Yes. Cheapflights offers flight deals from Panama City to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Santiago?

    Currently, March is the cheapest month in which you can book a flight from Panama City to Santiago (average of £189). Flying from Panama City to Santiago in July is currently the most expensive (average of £255). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar

Browse thousands of different options on Cheapflights for your next trip

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Complete your trip

Complete your trip to Santiago by adding a car hire and/or hotel booking to your travel itinerary.
Santiago car hire
Santiago Arturo Merino Benitez Airport car hire
Punta Arenas car hire
Balmaceda car hire
Puerto Montt car hire
Lastarria car hire

Top airline flying from Panama City to Santiago

Discover the top airline that operate flights from Panama City to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 15 October 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest£415Average£478FlexibilityNo cancel feeOn-time70%
Search Copa Airlines flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Panama City to Santiago?

900+ travel sites are searched through when a user searches for a flight using Cheapflights. From the search interface, users can use filters to choose airlines, airports, flight times, cabin classes and more to their preference. Book your flight to Santiago from Panama City today with Cheapflights!

Why should you use Cheapflights to find cheap flight tickets from Panama City to Santiago?

Millions of users choose and trust Cheapflights to book the best flight deals from Panama City to Santiago for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.

Can Cheapflights find flights from Panama City to Santiago with no change fees?

Yes, we can. To see specific flights from Panama City to Santiago with no change fees, users can toggle flexible booking options after using the search form above to find flights.

Can Cheapflights notify me if prices for flights from Panama City to Santiago become cheaper?

Yes, Cheapflights has a feature called Price Alert, which notifies users when flight prices change. Track prices for your flight to Santiago from Panama City today and book when prices fit your budget.

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