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Cheap flights from Quito to Santiago from £149

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/4. Fares are subject to change and may not be available on all flights or dates of travel.
UIO — SCL
20 Feb — 27 Feb1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Quito to Santiago

Enter your travel dates to find the best prices.

Cheapest flights from Quito to Santiago
Explore the most affordable flight options available from Quito to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 21 January 2026.

Sun 22/316:49
UIO
-
SCL
1 stop10h 25m
JetSMART
Fri 15/504:56
SCL
-
UIO
1 stop12h 08m
JetSMART
Deal found 20/1£261
Fri 8/516:49
UIO
-
SCL
1 stop10h 22m
JetSMART
Fri 22/504:56
SCL
-
UIO
1 stop12h 08m
JetSMART
Deal found 20/1£279
Wed 1/416:49
UIO
-
SCL
1 stop10h 27m
JetSMART
Wed 8/404:41
SCL
-
UIO
1 stop12h 23m
JetSMART
Deal found 20/1£282
Wed 25/316:49
UIO
-
SCL
1 stop15h 50m
JetSMART
Wed 1/405:41
SCL
-
UIO
1 stop12h 23m
JetSMART
Deal found 20/1£283
Fri 10/416:49
UIO
-
SCL
1 stop10h 22m
JetSMART
Sun 12/404:56
SCL
-
UIO
1 stop12h 08m
JetSMART
Deal found 20/1£288
Fri 15/516:49
UIO
-
SCL
1 stop10h 22m
JetSMART
Fri 29/504:56
SCL
-
UIO
1 stop12h 08m
JetSMART
Deal found 20/1£289
Sun 3/516:49
UIO
-
SCL
1 stop10h 27m
JetSMART
Fri 8/504:56
SCL
-
UIO
1 stop12h 08m
JetSMART
Deal found 20/1£297
Fri 3/416:49
UIO
-
SCL
1 stop10h 22m
JetSMART
Fri 10/404:56
SCL
-
UIO
1 stop12h 08m
JetSMART
Deal found 20/1£300
Fri 13/316:49
UIO
-
SCL
1 stop15h 50m
JetSMART
Sun 22/305:59
SCL
-
UIO
1 stop12h 01m
JetSMART
Deal found 19/1£308
Sun 5/716:49
UIO
-
SCL
1 stop10h 25m
JetSMART
Sun 19/704:59
SCL
-
UIO
1 stop12h 01m
JetSMART
Deal found 20/1£317
Fri 3/416:49
UIO
-
SCL
1 stop10h 22m
JetSMART
Sun 5/404:56
SCL
-
UIO
1 stop12h 08m
JetSMART
Deal found 20/1£319
Wed 15/716:49
UIO
-
SCL
1 stop10h 25m
JetSMART
Sun 19/704:59
SCL
-
UIO
1 stop12h 01m
JetSMART
Deal found 20/1£326

Find flight deals from Quito to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Quito (UIO) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 21 January 2026.

Round-trip from

£261

One-way from

£149

Popular in

February

Cheapest in

April

Average price

£320
JetSMART
  • JetSMART
  • 22/3-15/5
  • 2 total stops
  • 22h 33m total
  • Quito to Santiago
Search Deals
JetSMART
  • JetSMART
  • 12/4
  • 1 total stop
  • 10h 22m total
  • Quito to Santiago
Search Deals
Highest demand for flights based on searches. 11% potential increase in price (£27 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease (£6 potential savings vs. average return price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Quito to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 21 January 2026.
Use the filters below to find and compare flights from Quito to Santiago that are best for you.

Fly from

Quito

Fly to

Santiago

Route

Depart

Return

Price

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Wed 6/5

16:49-04:16

1 stop10h 27m

Santiago Arturo Merino Benitez

Wed 13/5

04:41-16:04

1 stop12h 23m

£261

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Fri 15/5

16:49-04:11

1 stop10h 22m

Santiago Arturo Merino Benitez

Sun 31/5

04:56-16:04

1 stop12h 08m

£261

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Sun 19/4

16:49-04:11

1 stop10h 22m

Santiago Arturo Merino Benitez

Sun 3/5

04:56-16:04

1 stop12h 08m

£261

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Fri 8/5

16:49-04:11

1 stop10h 22m

Santiago Arturo Merino Benitez

Fri 22/5

04:56-16:04

1 stop12h 08m

£279

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Fri 17/4

16:49-04:11

1 stop10h 22m

Santiago Arturo Merino Benitez

Fri 1/5

04:56-16:04

1 stop12h 08m

£279

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Wed 25/3

16:49-10:39

1 stop15h 50m

Santiago Arturo Merino Benitez

Wed 1/4

05:41-16:04

1 stop12h 23m

£283

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Fri 15/5

16:49-04:11

1 stop10h 22m

Santiago Arturo Merino Benitez

Fri 29/5

04:56-16:04

1 stop12h 08m

£289

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Fri 3/4

16:49-05:11

1 stop10h 22m

Santiago Arturo Merino Benitez

Fri 10/4

04:56-16:04

1 stop12h 08m

£300

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Sun 5/4

16:49-04:11

1 stop10h 22m

Santiago Arturo Merino Benitez

Sun 12/4

04:56-16:04

1 stop12h 08m

£300

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Fri 13/3

16:49-10:39

1 stop15h 50m

Santiago Arturo Merino Benitez

Sun 22/3

05:59-16:00

1 stop12h 01m

£308

Flights are sorted by cheapest return flights first.

Deals found on 19/1

Showing 1-10 of 20 results
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Best time to book a flight from Quito to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Quito with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Quito to Santiago

How far ahead should I book a flight from Quito to Santiago?

Use this chart to determine the optimal time to book a return flight from Quito to Santiago. Price data was last updated on 16 January 2026.

The best time to book flights from Quito to Santiago is 68 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Quito to Santiago?

Currently, March is the cheapest month in which you can book a flight from Quito to Santiago (average of £93). Flying from Quito to Santiago in December is currently the most expensive (average of £138). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Quito to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Quito to Santiago?

    A quick flight from Quito to Santiago can take about 10h 27m. JetSMART provides one of the quickest options available for as low as £261. Quito and Santiago are separated by a distance of 2349 mi.

  • Can I find deals for flights from Quito to Santiago that include hotel bookings?

    Yes. In addition to deals on Quito to Santiago flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Quito to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Quito to Santiago.

  • Can I find deals for business class flights from Quito to Santiago?

    Yes. Cheapflights offers flight deals from Quito to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Quito to Santiago?

    Currently, March is the cheapest month in which you can book a flight from Quito to Santiago (average of £93). Flying from Quito to Santiago in December is currently the most expensive (average of £138). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar

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Complete your trip

Complete your trip to Santiago by adding a car hire and/or hotel booking to your travel itinerary.
Santiago car hire
Santiago Arturo Merino Benitez Airport car hire
Punta Arenas car hire
Balmaceda car hire
Puerto Montt car hire
Lastarria car hire

Fly with Cheapflights

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How does Cheapflights help users find flights from Quito to Santiago?

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Why should you use Cheapflights to find cheap flight tickets from Quito to Santiago?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Quito to Santiago.

Can Cheapflights find flights from Quito to Santiago with no change fees?

Users can book flights with no change fees policies with our dedicated filters. Book flights from Quito to Santiago flexibly with Cheapflights today.

Can Cheapflights notify me if prices for flights from Quito to Santiago become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

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