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Cheap flights from Quito to Santiago from £199

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 15/9. Fares are subject to change and may not be available on all flights or dates of travel.
UIO — SCL
3 Sep — 10 Sep1
1 adult

Cheap flight deals from Quito to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Quito (UIO) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 29 August 2025.

Round-trip from

£312

One-way from

£199

Popular in

February

Cheapest in

April

Average price

£290
Avianca
  • Avianca
  • 11/10-18/10
  • 2 total stops
  • 28h 14m total
  • Quito to Santiago
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Copa Airlines
  • Copa Airlines
  • 10/9
  • 1 total stop
  • 18h 34m total
  • Quito to Santiago
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Highest demand for flights based on searches. 9% potential increase in price (£20 potential increase over avg. return price).
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Cheapest flight prices on average. 2% potential price decrease (£5 potential savings vs. average return price).
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Average for round-trip flights in August 2025
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Find flight deals from Quito to Santiago

Cheapest flights from Quito to Santiago
Explore the most affordable flight options available from Quito to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 29 August 2025.

Sat 11/1004:20UIO - SCL
1 stop17h 10mAvianca
Sat 18/1015:30SCL - UIO
1 stop11h 04mAvianca
Deal found 27/8£312
Sun 12/1016:56UIO - SCL
1 stop10h 05mMultiple Airlines
Sun 19/1015:30SCL - UIO
1 stop11h 04mMultiple Airlines
Deal found 28/8£312
Sat 11/1004:20UIO - SCL
1 stop17h 10mMultiple Airlines
Sat 18/1011:40SCL - UIO
2 stops13h 40mMultiple Airlines
Deal found 27/8£320
Sat 11/1018:37UIO - SCL
2 stops9h 08mLATAM Airlines
Sat 18/1011:40SCL - UIO
2 stops13h 40mLATAM Airlines
Deal found 27/8£327
Sat 11/1002:30UIO - SCL
1 stop9h 55mAvianca
Sun 19/1007:10SCL - UIO
1 stop9h 30mAvianca
Deal found 28/8£349

Cheapflights Fare Finder

 
Customise your flight search to find flights from Quito to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 29 August 2025.
Use the filters below to find and compare flights from Quito to Santiago that are best for you.

Fly from

Quito

Fly to

Santiago

Route

Depart

Return

Price

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Sat 11/10

04:20-23:30

1 stop17h 10m

Santiago Arturo Merino Benitez

Sat 18/10

15:30-00:34

1 stop11h 04m

£312

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Sun 12/10

16:56-05:01

1 stop10h 05m

Santiago Arturo Merino Benitez

Sun 19/10

15:30-00:34

1 stop11h 04m

£312

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Sat 11/10

04:20-23:30

1 stop17h 10m

Santiago Arturo Merino Benitez

Sat 18/10

11:40-23:20

2 stops13h 40m

£320

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Sat 11/10

18:37-05:45

2 stops9h 08m

Santiago Arturo Merino Benitez

Sat 18/10

11:40-23:20

2 stops13h 40m

£327

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Wed 4/2

12:00-05:30

2 stops15h 30m

Santiago Arturo Merino Benitez

Tue 3/3

01:35-08:55

1 stop9h 20m

£347

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Sat 11/10

02:30-14:25

1 stop9h 55m

Santiago Arturo Merino Benitez

Sun 19/10

07:10-14:40

1 stop9h 30m

£349

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Wed 10/9

03:06-23:40

1 stop18h 34m

£199

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Tue 9/9

03:06-00:04

1 stop18h 58m

£199

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Thu 11/9

03:06-00:04

1 stop18h 58m

£199

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Mon 15/9

03:06-00:04

1 stop18h 58m

£199

Flights are sorted by cheapest return flights first.

Deals found on 27/8

Showing 1-10 of 13 results
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Best time to book a flight from Quito to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Quito with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Quito to Santiago

How far ahead should I book a flight from Quito to Santiago?

Use this chart to determine the optimal time to book a return flight from Quito to Santiago. Price data was last updated on 22 August 2025.

The best time to book flights from Quito to Santiago is 77 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Quito to Santiago?

Currently, May is the cheapest month in which you can book a flight from Quito to Santiago (average of £1,031). Flying from Quito to Santiago in December is currently the most expensive (average of £1,468). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from UIO to SCL?

Find hourly flight availability from Quito to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 29 August 2025.

It’s optimal to fly from Quito to Santiago at midday. By choosing this option you can save up to 34% on the cost of your flight, compared to a flight in the morning.

Related info for your journey

Find useful and relevant information for your journey from Quito to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Quito to Santiago?

    A quick flight from Quito to Santiago can take about 9h 08m. Avianca provides one of the quickest options available for as low as £327. Quito and Santiago are separated by a distance of 2349 mi. Both multi-stop and direct flights can be found to your destination and back.

  • Can I find deals for flights from Quito to Santiago that include hotel bookings?

    Yes. In addition to deals on Quito to Santiago flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Quito to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Quito to Santiago.

  • Can I find deals for business class flights from Quito to Santiago?

    Yes. Cheapflights offers flight deals from Quito to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Quito to Santiago?

    Currently, May is the cheapest month in which you can book a flight from Quito to Santiago (average of £1,031). Flying from Quito to Santiago in December is currently the most expensive (average of £1,468). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar

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Complete your trip

Complete your trip to Santiago by adding a car hire and/or hotel booking to your travel itinerary.
Santiago car hire
Santiago Arturo Merino Benitez Airport car hire
Punta Arenas car hire
Balmaceda car hire
Puerto Montt car hire
Lastarria car hire

Fly with Cheapflights

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How does Cheapflights help users find flights from Quito to Santiago?

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Can Cheapflights find flights from Quito to Santiago with no change fees?

Users can book flights with no change fees policies with our dedicated filters. Book flights from Quito to Santiago flexibly with Cheapflights today.

Can Cheapflights notify me if prices for flights from Quito to Santiago become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

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