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Cheap flights from Quito to Santiago from £153

UIO — SCL
21 Sep — 28 Sep1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Quito to Santiago

Enter your travel dates to find the best prices.

Cheapest flights from Quito to Santiago

Fri 16/1016:48 -
1 stop10h 20m
Fri 30/1006:07 -
1 stop11h 57m
Deal found 18/8£268
Wed 9/916:48 -
1 stop10h 25m
Fri 25/906:07 -
1 stop11h 56m
Deal found 18/8£285
Fri 11/916:48 -
1 stop10h 15m
Sun 1/1106:07 -
1 stop11h 57m
Deal found 18/8£286
Wed 25/1116:50 -
1 stop10h 13m
Sun 29/1106:07 -
1 stop11h 57m
Deal found 21/8£289
Sun 13/916:48 -
1 stop10h 15m
Sun 13/1206:07 -
1 stop11h 57m
Deal found 18/8£295
Sun 6/916:48 -
1 stop10h 15m
Fri 4/1209:36 -
1 stop8h 28m
Deal found 18/8£303
Fri 20/1116:50 -
1 stop10h 13m
Wed 2/1206:07 -
1 stop11h 57m
Deal found 18/8£303
Sun 6/916:48 -
1 stop10h 15m
Sun 6/1206:07 -
1 stop11h 57m
Deal found 18/8£306
Fri 6/1116:50 -
1 stop10h 13m
Fri 20/1106:07 -
1 stop11h 57m
Deal found 17/8£306
Wed 9/916:48 -
1 stop10h 25m
Wed 16/905:47 -
1 stop12h 16m
Deal found 17/8£308
Sun 13/916:48 -
1 stop10h 15m
Fri 25/906:07 -
1 stop11h 56m
Deal found 18/8£309
Wed 2/916:48 -
1 stop10h 25m
Fri 18/906:07 -
1 stop11h 56m
Deal found 19/8£311

Find flight deals from Quito to Santiago

Round-trip from

£268

One-way from

£153

Popular in

February

Cheapest in

June

Average price

£296
JetSMART
  • JetSMART
  • 16/10-30/10
  • 2 total stops
  • 22h 17m total
  • Quito to Santiago
Search Deals
JetSMART
  • JetSMART
  • 11/9
  • 1 total stop
  • 10h 15m total
  • Quito to Santiago
Search Deals
Highest demand for flights based on searches. 8% potential increase in price (£21 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease (£6 potential savings vs. average return price).
Search Deals
Average for round-trip flights in August 2026
Search Deals

Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Quito to Santiago that are best for you.

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Depart

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Price

Cheapest return flight

QuitoSantiago

UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez

UIOSCL

Quito Mariscal Sucr

Fri 11/9

16:48-05:03

1 stop10h 15m

Santiago Arturo Merino Benitez

Sun 20/9

06:07-16:03

1 stop11h 56m

£285
Fastest return journey

QuitoSantiago

UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez

UIOSCL

Quito Mariscal Sucr

Wed 2/12

16:50-05:03

1 stop10h 13m

Santiago Arturo Merino Benitez

Mon 7/12

06:07-16:04

1 stop11h 57m

£303

QuitoSantiago

UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez

UIOSCL

Quito Mariscal Sucr

Sun 22/11

16:50-05:03

1 stop10h 13m

Santiago Arturo Merino Benitez

Fri 27/11

06:07-16:04

1 stop11h 57m

£303

QuitoSantiago

UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez

UIOSCL

Quito Mariscal Sucr

Fri 20/11

16:50-05:03

1 stop10h 13m

Santiago Arturo Merino Benitez

Wed 2/12

06:07-16:04

1 stop11h 57m

£303

QuitoSantiago

UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez

UIOSCL

Quito Mariscal Sucr

Sun 13/9

16:48-05:03

1 stop10h 15m

Santiago Arturo Merino Benitez

Sun 20/9

06:07-16:03

1 stop11h 56m

£309

QuitoSantiago

UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez

UIOSCL

Quito Mariscal Sucr

Wed 16/9

16:48-05:13

1 stop10h 25m

Santiago Arturo Merino Benitez

Sun 27/9

06:07-16:03

1 stop11h 56m

£312

QuitoSantiago

UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez

UIOSCL

Quito Mariscal Sucr

Wed 9/9

16:48-05:13

1 stop10h 25m

Santiago Arturo Merino Benitez

Wed 16/9

05:47-16:03

1 stop12h 16m

£314

QuitoSantiago

UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez

UIOSCL

Quito Mariscal Sucr

Wed 23/9

16:48-05:13

1 stop10h 25m

Santiago Arturo Merino Benitez

Sun 27/9

06:07-16:03

1 stop11h 56m

£319

QuitoSantiago

UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez

UIOSCL

Quito Mariscal Sucr

Wed 9/12

16:50-05:03

1 stop10h 13m

Santiago Arturo Merino Benitez

Mon 28/12

06:07-16:04

1 stop11h 57m

£328

QuitoSantiago

UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez

UIOSCL

Quito Mariscal Sucr

Sun 6/12

16:50-21:03

1 stop26h 13m

Santiago Arturo Merino Benitez

Tue 29/12

22:12-16:04

1 stop19h 52m

£328

Flights are sorted by cheapest return flights first.

Deals found on 21/8

Showing 1-10 of 22 resultsSorted by cheapest first
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Best time to book a flight from Quito to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Quito with our price prediction graph.
Estimated return price

Cheapflights Insights

Everything you need to know about your flight from Quito to Santiago

How far ahead should I book a flight from Quito to Santiago?

The best time to book flights from Quito to Santiago is 76 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Quito to Santiago?

Currently, June is the cheapest month in which you can book a flight from Quito to Santiago (average of £265). Flying from Quito to Santiago in February is currently the most expensive (average of £386). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost for a return flight from Quito to Santiago?

Airfare is typical for this route at the moment.

Quito to Santiago flights typically cost between £192 and £373 in October.
The cheapest return price found within the last 5 days was £268 on JetSMART (16 Oct–30 Oct).

Related info for your journey

  • How long is the flight from Quito to Santiago?

    A quick flight from Quito to Santiago can take about 10h 15m. JetSMART provides one of the quickest options available for as low as £285. Quito and Santiago are separated by a distance of 2349 mi.

  • Can I find deals for flights from Quito to Santiago that include hotel bookings?

    Yes. In addition to deals on Quito to Santiago flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Quito to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Quito to Santiago.

  • Can I find deals for business class flights from Quito to Santiago?

    Yes. Cheapflights offers flight deals from Quito to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Quito to Santiago?

    Currently, June is the cheapest month in which you can book a flight from Quito to Santiago (average of £265). Flying from Quito to Santiago in February is currently the most expensive (average of £386). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar

Browse thousands of different options on Cheapflights for your next trip

Complete your trip

Santiago car hire
Santiago Arturo Merino Benitez Airport car hire
Punta Arenas car hire
Balmaceda car hire
Lastarria car hire

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