How long is the flight from Santo Domingo to Santiago?

Airlines like Copa Airlines fly from Santo Domingo to Santiago in about 14h 38m. The time it takes to get you to your destination can typically vary by up to . Airlines will cover a distance of 3579 mi.

In terms of precipitation, rainfall in Santiago ranges from 0.0 - 70.0 inches per month. June is typically the wettest month, when rainfall can reach 70.0 mm. January is typically the driest time to visit Santiago when rainfall is around 0.0 mm.

If weather is an important factor for your trip to Santiago, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 21.0 C. Travellers hoping to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 8.0 C).

What is the cheapest time of day to fly from SDQ to SCL?

When flying from Santo Domingo to Santiago, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Can I find deals for flights from Santo Domingo to Santiago that include hotel bookings?

Yes. In addition to deals on Santo Domingo to Santiago flights, Cheapflights offers holiday packages that include both flights and hotel.

How can I find direct flights from Santo Domingo to Santiago?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santo Domingo to Santiago.

Can I find deals for business class flights from Santo Domingo to Santiago?

Yes. Cheapflights offers flight deals from Santo Domingo to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

£216+ Cheap Flights from Santo Domingo to Santiago

Cheap flight deals from Santo Domingo to Santiago

Enter your travel dates to find the best prices.

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Best

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One-way

Cheapest flights from Santo Domingo to Santiago
Explore the most affordable flight options available from Santo Domingo to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 27 September 2026.

Tue 6/1013:45 -

1 stop12h 50m

Mon 12/1006:00 -

1 stop11h 55m

Deal found 22/9£442

Tue 15/1213:40 -

1 stop12h 55m

Sat 2/109:25 -

1 stop13h 15m

Deal found 24/9£539

Sun 1/1119:06 -

1 stop27h 30m

Fri 6/1103:48 -

1 stop23h 20m

Deal found 23/9£574

Mon 19/1012:42 -

1 stop13h 04m

Sat 31/1005:22 -

1 stop21h 46m

Deal found 23/9£675

Mon 7/1214:14 -

1 stop14h 38m

Mon 28/1205:07 -

1 stop22h 01m

Deal found 25/9£695

Thu 24/1205:53 -

1 stop16h 42m

Sun 3/103:53 -

1 stop23h 11m

Deal found 23/9£766

Mon 7/1216:18 -

2 stops39h 32m

Mon 28/1222:45 -

2 stops26h 01m

Deal found 25/9£1,263

Sun 15/1116:18 -

2 stops39h 32m

Mon 30/1122:45 -

2 stops41h 21m

Deal found 27/9£1,273

Find flight deals from Santo Domingo to Santiago

Round-trip from	£539
One-way from	£216
Popular in	January
Cheapest in	June
Average price	£534

15/12-2/1
2 total stops
26h 10m total
Santo Domingo to Santiago

Search Deals

1/12-31/12
1 total stop
12h 55m total
Santo Domingo to Santiago

Search Deals

Highest demand for flights based on searches. 9% potential increase in price (£44 potential increase over avg. return price).

Search Deals

Cheapest flight prices on average. 1% potential price decrease (£7 potential savings vs. average return price).

Search Deals

Average for round-trip flights in September 2026

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Santo Domingo to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

Santo DomingoSantiago

SDQ Santo Domingo Las Americas - SCL Santiago Arturo Merino Benitez

SDQSCL

Santo Domingo Las Americas

Tue 6/10

13:45-03:35

1 stop12h 50m

Santiago Arturo Merino Benitez

Wed 31/12

00:00-22:30

Nonstop0h 00m

£223

Santo DomingoSantiago

SDQ Santo Domingo Las Americas - SCL Santiago Arturo Merino Benitez

SDQSCL

Santo Domingo Las Americas

Tue 5/1

13:40-03:35

1 stop12h 55m

Santiago Arturo Merino Benitez

Wed 31/12

00:00-22:30

Nonstop0h 00m

£235

Santo DomingoSantiago

SDQ Santo Domingo Las Americas - SCL Santiago Arturo Merino Benitez

SDQSCL

Santo Domingo Las Americas

Tue 3/11

13:40-03:35

1 stop12h 55m

Santiago Arturo Merino Benitez

Wed 31/12

00:00-22:30

Nonstop0h 00m

£246

Santo DomingoSantiago

SDQ Santo Domingo Las Americas - SCL Santiago Arturo Merino Benitez

SDQSCL

Santo Domingo Las Americas

Thu 29/10

13:45-03:35

1 stop12h 50m

Santiago Arturo Merino Benitez

Wed 31/12

00:00-22:30

Nonstop0h 00m

£246

Santo DomingoSantiago

SDQ Santo Domingo Las Americas - SCL Santiago Arturo Merino Benitez

SDQSCL

Santo Domingo Las Americas

Fri 30/10

08:55-23:55

1 stop14h 00m

Santiago Arturo Merino Benitez

Wed 31/12

00:00-22:30

Nonstop0h 00m

£264

Santo DomingoSantiago

SDQ Santo Domingo Las Americas - SCL Santiago Arturo Merino Benitez

SDQSCL

Santo Domingo Las Americas

Tue 27/10

08:57-23:39

1 stop13h 42m

Santiago Arturo Merino Benitez

Wed 31/12

00:00-22:30

Nonstop0h 00m

£336

Santo DomingoSantiago

SDQ Santo Domingo Las Americas - SCL Santiago Arturo Merino Benitez

SDQSCL

Santo Domingo Las Americas

Sun 25/10

12:48-00:22

1 stop10h 34m

Santiago Arturo Merino Benitez

Wed 31/12

00:00-22:30

Nonstop0h 00m

£336

Santo DomingoSantiago

SDQ Santo Domingo Las Americas - SCL Santiago Arturo Merino Benitez

SDQSCL

Santo Domingo Las Americas

Sat 7/11

12:10-23:36

1 stop10h 26m

Santiago Arturo Merino Benitez

Wed 31/12

00:00-22:30

Nonstop0h 00m

£336

Fastest return journey

Santo DomingoSantiago

SDQ Santo Domingo Las Americas - SCL Santiago Arturo Merino Benitez

SDQSCL

Santo Domingo Las Americas

Mon 5/10

12:42-23:39

1 stop9h 57m

Santiago Arturo Merino Benitez

Wed 31/12

00:00-22:30

Nonstop0h 00m

£336

Santo DomingoSantiago

SDQ Santo Domingo Las Americas - SCL Santiago Arturo Merino Benitez

SDQSCL

Santo Domingo Las Americas

Fri 6/11

12:45-02:48

1 stop13h 03m

Santiago Arturo Merino Benitez

Wed 31/12

00:00-22:30

Nonstop0h 00m

£336

Flights are sorted by cheapest return flights first.

Deals found on 22/9

Showing 1-10 of 15 resultsSorted by cheapest first

Best time to book a flight from Santo Domingo to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Santo Domingo with our price prediction graph.

SDQ-SCL

Estimated return price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santo Domingo to Santiago

How far ahead should I book a flight from Santo Domingo to Santiago?

The best time to book flights from Santo Domingo to Santiago is 61 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Santo Domingo to Santiago?

Currently, June is the cheapest month in which you can book a flight from Santo Domingo to Santiago (average of £306). Flying from Santo Domingo to Santiago in January is currently the most expensive (average of £617). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost for a return flight from Santo Domingo to Santiago?

Airfare is typical for this route at the moment.

Santo Domingo to Santiago flights typically cost between £528 and £617 in December.
The cheapest return price found within the last 5 days was £539 on Multiple Airlines (15 Dec–2 Jan).

Related info for your journey

How long is the flight from Santo Domingo to Santiago?
Airlines like Copa Airlines fly from Santo Domingo to Santiago in about 14h 38m. The time it takes to get you to your destination can typically vary by up to . Airlines will cover a distance of 3579 mi.
Can I find deals for flights from Santo Domingo to Santiago that include hotel bookings?
Yes. In addition to deals on Santo Domingo to Santiago flights, Cheapflights offers holiday packages that include both flights and hotel.
How can I find direct flights from Santo Domingo to Santiago?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santo Domingo to Santiago.
Can I find deals for business class flights from Santo Domingo to Santiago?
Yes. Cheapflights offers flight deals from Santo Domingo to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Santo Domingo to Santiago?
Currently, June is the cheapest month in which you can book a flight from Santo Domingo to Santiago (average of £306). Flying from Santo Domingo to Santiago in January is currently the most expensive (average of £617). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Cheap flights from Santo Domingo to Santiago from £216

This is the cheapest retur flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/12. Fares are subject to change and may not be available on all flights or dates of travel.

Cheap flight deals from Santo Domingo to Santiago

Cheapest flights from Santo Domingo to SantiagoExplore the most affordable flight options available from Santo Domingo to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 27 September 2026.

Explore the most affordable flight options available from Santo Domingo to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 27 September 2026.

Best flights from Santo Domingo to SantiagoDiscover carefully curated flight deals from Santo Domingo to Santiago that have cost, travel time, and stopovers in mind to ensure you get the best travel experience. Data last updated 27 September 2026.

Discover carefully curated flight deals from Santo Domingo to Santiago that have cost, travel time, and stopovers in mind to ensure you get the best travel experience. Data last updated 27 September 2026.

Last-minute flights from Santo Domingo to SantiagoDiscover last-minute flight deals from Santo Domingo to Santiago. Data last updated 27 September 2026 and is based on user searches.

Discover last-minute flight deals from Santo Domingo to Santiago. Data last updated 27 September 2026 and is based on user searches.

One-way flights from Santo Domingo to SantiagoSearch for one-way flight options from Santo Domingo to Santiago. Find affordable one-way fares based on user searches. Data last updated 27 September 2026.

Search for one-way flight options from Santo Domingo to Santiago. Find affordable one-way fares based on user searches. Data last updated 27 September 2026.

Find flight deals from Santo Domingo to Santiago

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Cheapflights Fare Finder

Use the filters below to find and compare flights from Santo Domingo to Santiago that are best for you.

Best time to book a flight from Santo Domingo to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Santo Domingo with our price prediction graph.

Cheapflights Insights

How far ahead should I book a flight from Santo Domingo to Santiago?

The best time to book flights from Santo Domingo to Santiago is 61 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Santo Domingo to Santiago?

How much does it cost for a return flight from Santo Domingo to Santiago?

Airfare is typical for this route at the moment.

Santo Domingo to Santiago flights typically cost between £528 and £617 in December.The cheapest return price found within the last 5 days was £539 on Multiple Airlines (15 Dec–2 Jan).

Related info for your journey

How long is the flight from Santo Domingo to Santiago?

Can I find deals for flights from Santo Domingo to Santiago that include hotel bookings?

How can I find direct flights from Santo Domingo to Santiago?

Can I find deals for business class flights from Santo Domingo to Santiago?

What is the cheapest month to book a flight from Santo Domingo to Santiago?

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How does Cheapflights help users find flights from Santo Domingo to Santiago?

Why should you use Cheapflights to find cheap flight tickets from Santo Domingo to Santiago?

Can Cheapflights find flights from Santo Domingo to Santiago with no change fees?

Can Cheapflights notify me if prices for flights from Santo Domingo to Santiago become cheaper?

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Cheapest flights from Santo Domingo to Santiago
Explore the most affordable flight options available from Santo Domingo to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 27 September 2026.

Best flights from Santo Domingo to Santiago
Discover carefully curated flight deals from Santo Domingo to Santiago that have cost, travel time, and stopovers in mind to ensure you get the best travel experience. Data last updated 27 September 2026.

Last-minute flights from Santo Domingo to Santiago
Discover last-minute flight deals from Santo Domingo to Santiago. Data last updated 27 September 2026 and is based on user searches.

One-way flights from Santo Domingo to Santiago
Search for one-way flight options from Santo Domingo to Santiago. Find affordable one-way fares based on user searches. Data last updated 27 September 2026.

Santo Domingo to Santiago flights typically cost between £528 and £617 in December.
The cheapest return price found within the last 5 days was £539 on Multiple Airlines (15 Dec–2 Jan).