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Cheap flights from Guatemala City to Santo Domingo from £151

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 16/2. Fares are subject to change and may not be available on all flights or dates of travel.
GUA — SDQ
27 Feb — 6 Mar1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Guatemala City to Santo Domingo

Enter your travel dates to find the best prices.

Cheapest flights from Guatemala City to Santo Domingo
Explore the most affordable flight options available from Guatemala City to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 28 January 2026.

Thu 19/304:24
GUA
-
SDQ
1 stop6h 47m
Copa Airlines
Mon 23/311:56
SDQ
-
GUA
1 stop13h 15m
Copa Airlines
Deal found 26/1£219
Thu 2/406:24
GUA
-
SDQ
2 stops27h 17m
Copa Airlines
Tue 7/406:02
SDQ
-
GUA
2 stops17h 39m
Copa Airlines
Deal found 28/1£233
Tue 3/306:24
GUA
-
SDQ
2 stops7h 50m
Copa Airlines
Tue 10/308:48
SDQ
-
GUA
2 stops14h 52m
Copa Airlines
Deal found 26/1£239
Mon 2/306:24
GUA
-
SDQ
2 stops17h 54m
Copa Airlines
Mon 9/311:56
SDQ
-
GUA
2 stops11h 44m
Copa Airlines
Deal found 27/1£245
Mon 23/204:24
GUA
-
SDQ
1 stop11h 41m
Copa Airlines
Sat 28/219:05
SDQ
-
GUA
1 stop15h 50m
Copa Airlines
Deal found 27/1£247
Sat 31/118:15
GUA
-
SDQ
Nonstop3h 35m
Arajet
Mon 2/207:09
SDQ
-
GUA
Nonstop3h 36m
Arajet
Deal found 27/1£253
Mon 30/316:33
GUA
-
SDQ
1 stop7h 43m
Copa Airlines
Mon 6/412:08
SDQ
-
GUA
1 stop13h 02m
Copa Airlines
Deal found 27/1£258
Mon 6/406:24
GUA
-
SDQ
2 stops17h 56m
Copa Airlines
Mon 20/408:43
SDQ
-
GUA
2 stops14h 58m
Copa Airlines
Deal found 26/1£264
Thu 26/206:24
GUA
-
SDQ
2 stops9h 41m
Copa Airlines
Mon 2/308:48
SDQ
-
GUA
2 stops14h 52m
Copa Airlines
Deal found 26/1£268
Thu 26/308:25
GUA
-
SDQ
Nonstop3h 35m
Arajet
Sat 28/315:54
SDQ
-
GUA
Nonstop3h 36m
Arajet
Deal found 27/1£269
Sat 14/307:09
GUA
-
SDQ
1 stop7h 05m
Copa Airlines
Sat 21/311:56
SDQ
-
GUA
2 stops11h 44m
Copa Airlines
Deal found 28/1£272
Thu 2/406:24
GUA
-
SDQ
2 stops27h 17m
Copa Airlines
Mon 6/412:08
SDQ
-
GUA
1 stop12h 38m
Copa Airlines
Deal found 27/1£272

Find flight deals from Guatemala City to Santo Domingo

Discover tips and strategies to find the most affordable flight options for your journey from Guatemala City (GUA) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 28 January 2026.

Round-trip from

£219

One-way from

£151

Popular in

April

Cheapest in

May

Average price

£217
Copa Airlines
  • Copa Airlines
  • 14/4-16/4
  • 4 total stops
  • 22h 48m total
  • Guatemala City to Santo Domingo
Search Deals
WorldTicket
  • WorldTicket
  • 16/2
  • Nonstop
  • 3h 35m total
  • Guatemala City to Santo Domingo
Search Deals
Highest demand for flights based on searches. 0% potential increase in price (£1 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease (£4 potential savings vs. average return price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Guatemala City to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 28 January 2026.
Use the filters below to find and compare flights from Guatemala City to Santo Domingo that are best for you.

Fly from

Guatemala City

Fly to

Santo Domingo

Route

Depart

Return

Price

Guatemala CitySanto Domingo

GUA - SDQ

GUASDQ

Guatemala City La Aurora

Thu 19/3

06:24-16:14

2 stops7h 50m

Santo Domingo Las Americas

Tue 24/3

08:48-22:39

1 stop15h 51m

£219

Guatemala CitySanto Domingo

GUA - SDQ

GUASDQ

Guatemala City La Aurora

Sat 21/3

16:27-02:18

1 stop7h 51m

Santo Domingo Las Americas

Tue 24/3

14:13-21:40

2 stops9h 27m

£219

Guatemala CitySanto Domingo

GUA - SDQ

GUASDQ

Guatemala City La Aurora

Sat 2/5

06:24-16:15

2 stops7h 51m

Santo Domingo Las Americas

Sat 9/5

14:14-21:41

2 stops9h 27m

£219

Guatemala CitySanto Domingo

GUA - SDQ

GUASDQ

Guatemala City La Aurora

Tue 24/3

06:24-16:14

2 stops7h 50m

Santo Domingo Las Americas

Tue 31/3

12:41-22:37

1 stop11h 56m

£219

Guatemala CitySanto Domingo

GUA - SDQ

GUASDQ

Guatemala City La Aurora

Tue 7/4

06:24-16:14

2 stops7h 50m

Santo Domingo Las Americas

Sat 11/4

18:37-09:36

1 stop16h 59m

£219

Guatemala CitySanto Domingo

GUA - SDQ

GUASDQ

Guatemala City La Aurora

Thu 14/5

06:24-22:56

2 stops14h 32m

Santo Domingo Las Americas

Mon 18/5

08:45-21:41

2 stops14h 56m

£219

Guatemala CitySanto Domingo

GUA - SDQ

GUASDQ

Guatemala City La Aurora

Mon 30/3

10:33-02:16

1 stop13h 43m

Santo Domingo Las Americas

Mon 6/4

18:37-08:49

1 stop16h 12m

£219

Guatemala CitySanto Domingo

GUA - SDQ

GUASDQ

Guatemala City La Aurora

Sat 30/5

04:24-13:13

1 stop6h 49m

Santo Domingo Las Americas

Sat 13/6

12:10-21:41

2 stops11h 31m

£219

Guatemala CitySanto Domingo

GUA - SDQ

GUASDQ

Guatemala City La Aurora

Tue 9/6

10:35-22:56

1 stop10h 21m

Santo Domingo Las Americas

Sat 13/6

18:39-08:47

1 stop16h 08m

£219

Guatemala CitySanto Domingo

GUA - SDQ

GUASDQ

Guatemala City La Aurora

Thu 28/5

06:24-22:56

2 stops14h 32m

Santo Domingo Las Americas

Sat 30/5

18:39-08:47

1 stop16h 08m

£219

Flights are sorted by cheapest return flights first.

Deals found on 27/1

Showing 1-10 of 14 results
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Best time to book a flight from Guatemala City to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Guatemala City with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Guatemala City to Santo Domingo

How far ahead should I book a flight from Guatemala City to Santo Domingo?

Use this chart to determine the optimal time to book a return flight from Guatemala City to Santo Domingo. Price data was last updated on 23 January 2026.

The price you pay for your flight from Guatemala City to Santo Domingo may vary depending on when you book. For the best chance of a lower fare, look to book 56 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Guatemala City to Santo Domingo?

Currently, October is the cheapest month in which you can book a flight from Guatemala City to Santo Domingo (average of £100). Flying from Guatemala City to Santo Domingo in February is currently the most expensive (average of £147). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from GUA to SDQ?

Find hourly flight availability from Guatemala City to Santo Domingo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 28 January 2026.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Guatemala City to Santo Domingo as you normally would.

Related info for your journey

Find useful and relevant information for your journey from Guatemala City to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Guatemala City to Santo Domingo flight route?

    Within the past month, 2 users have taken a look at flights from Guatemala City La Aurora to Santo Domingo Las Americas.

  • How long is the flight from Guatemala City to Santo Domingo?

    There are many flights that can get you from Guatemala City to Santo Domingo in 11h 43m. Fly via Copa Airlines to get the fastest option. Guatemala City and Santo Domingo are separated by a distance of 1405 mi.

  • Can I find deals for flights from Guatemala City to Santo Domingo that include hotel bookings?

    Yes. In addition to deals on Guatemala City to Santo Domingo flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Guatemala City to Santo Domingo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Guatemala City to Santo Domingo.

  • Can I find deals for business class flights from Guatemala City to Santo Domingo?

    Yes. Cheapflights offers flight deals from Guatemala City to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Guatemala City to Santo Domingo?

    Currently, October is the cheapest month in which you can book a flight from Guatemala City to Santo Domingo (average of £100). Flying from Guatemala City to Santo Domingo in February is currently the most expensive (average of £147). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

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