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Cheap flights from Lisbon to São Tomé from £313

LIS — TMS
5 Dec — 12 Dec1
1 adult
1 adult, Economy, 0 bags
Cheapflights Tip: The best prices from Lisbon Humberto Delgado to Sao Tome Is are usually found in March or February, booked 42 days in advance, depart on a Thursday or Saturday and return on a Wednesday

Cheap flight deals from Lisbon to São Tomé

Enter your travel dates to find the best prices.

Cheapest flights from Lisbon to São Tomé

Sun 1/1109:35 -
1 stop8h 40m
Sat 7/1122:25 -
Nonstop6h 40m
Deal found 1/11£523
Fri 13/1100:05 -
Nonstop6h 15m
Sat 5/1207:50 -
Nonstop6h 15m
Deal found 3/11£524
Wed 11/1109:35 -
1 stop8h 40m
Sat 28/1122:25 -
Nonstop6h 40m
Deal found 2/11£541
Wed 11/1109:35 -
1 stop8h 40m
Fri 27/1120:00 -
1 stop9h 05m
Deal found 2/11£543
Sat 21/1110:50 -
Nonstop6h 40m
Sat 5/1222:25 -
Nonstop6h 40m
Deal found 1/11£547
Fri 6/1100:05 -
Nonstop6h 15m
Sat 5/1207:50 -
Nonstop6h 15m
Deal found 1/11£557
Fri 13/1100:05 -
Nonstop6h 15m
Sat 21/1107:50 -
Nonstop6h 15m
Deal found 4/11£557
Fri 6/1100:05 -
Nonstop6h 15m
Sat 14/1107:50 -
Nonstop6h 15m
Deal found 1/11£590
Fri 13/1100:05 -
Nonstop6h 15m
Sat 21/1107:50 -
Nonstop6h 15m
Deal found 31/10£591

Find flight deals from Lisbon to São Tomé

Round-trip from

£497

One-way from

£313

Popular in

August

Cheapest in

March

Average price

£563

Good round-trip deal

£549 or less
STP Airways
  • STP Airways
  • 5/3-13/3
  • Nonstop
  • 12h 30m total
  • Lisbon to São Tomé
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TAP AIR PORTUGAL
  • TAP AIR PORTUGAL
  • 13/1-31/12
  • 1 total stop
  • 8h 40m total
  • Lisbon to São Tomé
Search Deals
Highest demand for flights based on searches. 16% potential increase in price (£93 potential increase over avg. return price).
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Cheapest flight prices on average. 2% potential price decrease (£12 potential savings vs. average return price).
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Average for round-trip flights in November 2026
Search Deals
Price to beat on a round-trip flight from Lisbon Humberto Delgado to Sao Tome Is.
Search Deals

Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Lisbon to São Tomé that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

LisbonSão Tomé

LIS Lisbon Humberto Delgado - TMS Sao Tome Is

LISTMS

Lisbon Humberto Delgado

Wed 13/1

09:35-18:15

1 stop8h 40m

Sao Tome Is

Wed 31/12

00:00-01:00

Nonstop0h 00m

£313

LisbonSão Tomé

LIS Lisbon Humberto Delgado - TMS Sao Tome Is

LISTMS

Lisbon Humberto Delgado

Fri 12/3

10:15-18:55

1 stop8h 40m

Sao Tome Is

Wed 31/12

00:00-01:00

Nonstop0h 00m

£314
Fastest return journey

LisbonSão Tomé

LIS Lisbon Humberto Delgado - TMS Sao Tome Is

LISTMS

Lisbon Humberto Delgado

Fri 18/12

00:05-06:20

Nonstop6h 15m

Sao Tome Is

Wed 31/12

00:00-01:00

Nonstop0h 00m

£327

LisbonSão Tomé

LIS Lisbon Humberto Delgado - TMS Sao Tome Is

LISTMS

Lisbon Humberto Delgado

Fri 13/11

00:05-06:20

Nonstop6h 15m

Sao Tome Is

Wed 31/12

00:00-01:00

Nonstop0h 00m

£327

LisbonSão Tomé

LIS Lisbon Humberto Delgado - TMS Sao Tome Is

LISTMS

Lisbon Humberto Delgado

Fri 15/1

10:15-18:55

1 stop8h 40m

Sao Tome Is

Wed 31/12

00:00-01:00

Nonstop0h 00m

£483

LisbonSão Tomé

LIS Lisbon Humberto Delgado - TMS Sao Tome Is

LISTMS

Lisbon Humberto Delgado

Wed 25/11

09:35-18:15

1 stop8h 40m

Sao Tome Is

Wed 31/12

00:00-01:00

Nonstop0h 00m

£502

LisbonSão Tomé

LIS Lisbon Humberto Delgado - TMS Sao Tome Is

LISTMS

Lisbon Humberto Delgado

Fri 5/3

00:05-06:20

Nonstop6h 15m

Sao Tome Is

Sat 13/3

07:50-14:05

Nonstop6h 15m

£511

LisbonSão Tomé

LIS Lisbon Humberto Delgado - TMS Sao Tome Is

LISTMS

Lisbon Humberto Delgado

Fri 26/2

00:05-06:20

Nonstop6h 15m

Sao Tome Is

Sat 6/3

07:50-14:05

Nonstop6h 15m

£544

LisbonSão Tomé

LIS Lisbon Humberto Delgado - TMS Sao Tome Is

LISTMS

Lisbon Humberto Delgado

Fri 12/3

10:15-18:55

1 stop8h 40m

Sao Tome Is

Sat 27/3

22:25-05:05

Nonstop6h 40m

£552

LisbonSão Tomé

LIS Lisbon Humberto Delgado - TMS Sao Tome Is

LISTMS

Lisbon Humberto Delgado

Fri 2/4

00:05-05:35

Nonstop6h 30m

Sao Tome Is

Sat 17/4

07:05-14:35

Nonstop6h 30m

£557

Flights are sorted by cheapest return flights first.

Deals found on 3/11

Showing 1-10 of 18 resultsSorted by cheapest first
1
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Best time to book a flight from Lisbon to São Tomé

Have a flexible travel schedule? Discover the best time to fly to São Tomé from Lisbon with our price prediction graph.
Estimated return price

Cheapflights Insights

Everything you need to know about your flight from Lisbon to São Tomé

How far ahead should I book a flight from Lisbon to São Tomé?

To ensure you get the cheapest price possible for a flight from Lisbon to São Tomé, you should look to book at least 41 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Lisbon to São Tomé?

Currently, March is the cheapest month in which you can book a flight from Lisbon to São Tomé (average of £503). Flying from Lisbon to São Tomé in August is currently the most expensive (average of £796). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from LIS to TMS?

When flying from Lisbon to São Tomé, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

How much does it cost for a return flight from Lisbon to São Tomé?

Airfare is typical for this route at the moment.

Lisbon to São Tomé flights typically cost between £480 and £675 in March.
The cheapest return price found within the last 5 days was £497 on STP Airways (5 Mar–13 Mar).

Reviews of airlines servicing São Tomé

Read reviews from past customers who have flown with TAP AIR PORTUGAL from Lisbon to São Tomé. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
TAP AIR PORTUGAL
7.2
Good
2,395 reviews
Check prices

Boarding

7.1

Entertainment

6.4

Comfort

7.2

Crew

7.8

Food

6.3

Overall

7.2

Reviews

1 / 20
2.0
Mediocre

Scott,Oct 2026

LIS - MIA

I don't understand why an aircraft that arrived in Lisbon at 5;19am for a 10:35 flight was immediately delayed until 11am , then 11:17 am. Also, after being on the plane and taxiing for an hour, they discovered a computer error and we had to change planes. All in all we had a 5 1/2 hour delay. The boarding process for the second plane was chaos. They herded everyone out of the boarding area behind ropes, and then didn't announce anything over the loud speaker, but had a single agent yelling Premium only. Needless to say, there was pushing, yelling and confusion. On board, I have never experienced such a lazy, lethargic crew. We were in business class. We were not offered a drink or the usual bowl of nuts. We were given lunch about an hour into the trip. the food was mediocre at best. My friend, who had preordered the pasta dish over a week ago, was told that they were out of it and she could only have octopus, which she does not eat. Meanwhile, she saw 3 other passengers get pasta that they had not preordered. Shouldn't the pre orders be given priority? For the next 6 hours, we did not see a flight attendant, until they announced that they would not be serving another meal because they were "overworked". (same crew that was on the first aborted flight). Fortunately, I had to use the restroom and noticed a basket with sandwiches and some cookies. I asked the flight attendant if I could have one, and she said "of course, these are for you". Nobody let anybody know that there was food available., and no one was offered any drinks for 6 hours. I had to get up and ask for a bottle of water. Finally, they never came around to collect trash, so I left my trash at my seat. I will do everything in my power to not have to fly TAP again. Also, I think there is a law in Europe that passengers delayed more than 3 hours are entitled to some form of compensation. I will pursue this.
TAP AIR PORTUGAL
7.2
Good
2,395 reviews
TAP AIR PORTUGAL
7.2
Good
2,395 reviews
Check prices

Boarding

7.1

Entertainment

6.4

Comfort

7.2

Crew

7.8

Food

6.3

Overall

7.2

Reviews

1 / 20
2.0
Mediocre

Scott,Oct 2026

LIS - MIA

I don't understand why an aircraft that arrived in Lisbon at 5;19am for a 10:35 flight was immediately delayed until 11am , then 11:17 am. Also, after being on the plane and taxiing for an hour, they discovered a computer error and we had to change planes. All in all we had a 5 1/2 hour delay. The boarding process for the second plane was chaos. They herded everyone out of the boarding area behind ropes, and then didn't announce anything over the loud speaker, but had a single agent yelling Premium only. Needless to say, there was pushing, yelling and confusion. On board, I have never experienced such a lazy, lethargic crew. We were in business class. We were not offered a drink or the usual bowl of nuts. We were given lunch about an hour into the trip. the food was mediocre at best. My friend, who had preordered the pasta dish over a week ago, was told that they were out of it and she could only have octopus, which she does not eat. Meanwhile, she saw 3 other passengers get pasta that they had not preordered. Shouldn't the pre orders be given priority? For the next 6 hours, we did not see a flight attendant, until they announced that they would not be serving another meal because they were "overworked". (same crew that was on the first aborted flight). Fortunately, I had to use the restroom and noticed a basket with sandwiches and some cookies. I asked the flight attendant if I could have one, and she said "of course, these are for you". Nobody let anybody know that there was food available., and no one was offered any drinks for 6 hours. I had to get up and ask for a bottle of water. Finally, they never came around to collect trash, so I left my trash at my seat. I will do everything in my power to not have to fly TAP again. Also, I think there is a law in Europe that passengers delayed more than 3 hours are entitled to some form of compensation. I will pursue this.

Related info for your journey

  • How popular is this Lisbon to São Tomé flight route?

    Flights from Lisbon Humberto Delgado to Sao Tome Is have been viewed 38 times in the past calendar month.

  • How long is the flight from Lisbon to São Tomé?

    For as low as £511, STP Airways can have you in São Tomé from Lisbon in 6h 15m. Airlines will cover a distance of 2835 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Lisbon to São Tomé round-trip?

    TAAG, at £223, was found to be the cheapest airline from Lisbon to São Tomé.Alternate airlines flying return to your destination include TAP AIR PORTUGAL and STP Airways. TAAG is priced at 64% lower than the current average price of a flight leaving 3 months from now.

  • What are the most reliable airlines from Lisbon to São Tomé?

    No one likes to see their flight delayed. When booking a flight from Lisbon to São Tomé consider choosing Turkish Airlines (100%), TAP AIR PORTUGAL (92%) or EuroAtlantic Airways (67%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Lisbon to São Tomé?

    Looking at all options, your cheapest flight can be booked for £547. While the most popular route (Lisbon Humberto Delgado - Sao Tome Is) can be booked for £408 on average, our data indicates £581 when flying from Lisbon to São Tomé.

  • Can I find deals for flights from Lisbon to São Tomé that include hotel bookings?

    Yes. In addition to deals on Lisbon to São Tomé flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Lisbon to São Tomé?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Lisbon to São Tomé.

  • Can I find deals for business class flights from Lisbon to São Tomé?

    Yes. Cheapflights offers flight deals from Lisbon to São Tomé by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Lisbon to São Tomé?

    Currently, March is the cheapest month in which you can book a flight from Lisbon to São Tomé (average of £503). Flying from Lisbon to São Tomé in August is currently the most expensive (average of £796). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 4 airlines flying from Lisbon to São Tomé

AirlineCheapestAverageFlexibilityOn-time
TAAGCheapest£223Average£405FlexibilityNo cancel feeOn-time58%
Search TAAG flights
TAP AIR PORTUGALCheapest£326Average£701FlexibilityNo cancel feeOn-timeN/A
Search TAP AIR PORTUGAL flights
STP AirwaysCheapest£414Average£728FlexibilityNo cancel feeOn-timeN/A
Search STP Airways flights
EuroAtlantic AirwaysCheapest£579Average£772FlexibilityNo cancel feeOn-timeN/A
Search EuroAtlantic Airways flights

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