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Cheap flights from Panama City to Manchester from £448

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 28/4. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — MAN
22 May — 29 May1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Panama City to Manchester

Enter your travel dates to find the best prices.

Cheapest flights from Panama City to Manchester
Explore the most affordable flight options available from Panama City to Manchester. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 22 April 2026.

Thu 4/620:25
PTY
-
MAN
1 stop20h 20m
Multiple Airlines
Thu 11/605:45
MAN
-
PTY
2 stops18h 55m
Multiple Airlines
Deal found 20/4£778
Sun 4/1021:05
PTY
-
MAN
2 stops18h 25m
Multiple Airlines
Wed 4/1108:55
MAN
-
PTY
2 stops17h 10m
Multiple Airlines
Deal found 21/4£783
Fri 18/915:30
PTY
-
MAN
3 stops33h 00m
United Airlines
Mon 21/906:05
MAN
-
PTY
2 stops19h 26m
United Airlines
Deal found 20/4£791
Mon 1/605:30
PTY
-
MAN
3 stops34h 50m
Multiple Airlines
Mon 8/620:10
MAN
-
PTY
3 stops34h 25m
Multiple Airlines
Deal found 19/4£802
Tue 2/620:25
PTY
-
MAN
1 stop22h 20m
Multiple Airlines
Tue 9/609:30
MAN
-
PTY
1 stop15h 10m
Multiple Airlines
Deal found 17/4£824
Mon 18/522:20
PTY
-
MAN
1 stop29h 15m
Turkish Airlines
Tue 2/610:40
MAN
-
PTY
1 stop39h 45m
Turkish Airlines
Deal found 17/4£825
Mon 18/520:25
PTY
-
MAN
1 stop16h 55m
Multiple Airlines
Tue 2/613:35
MAN
-
PTY
2 stops41h 00m
Multiple Airlines
Deal found 17/4£850
Mon 18/520:25
PTY
-
MAN
1 stop16h 55m
Multiple Airlines
Wed 3/606:35
MAN
-
PTY
2 stops24h 00m
Multiple Airlines
Deal found 17/4£861
Fri 22/521:30
PTY
-
MAN
1 stop32h 00m
Multiple Airlines
Fri 29/518:15
MAN
-
PTY
2 stops30h 25m
Multiple Airlines
Deal found 21/4£867
Mon 8/609:45
PTY
-
MAN
2 stops38h 45m
United Airlines
Fri 12/609:00
MAN
-
PTY
2 stops25h 04m
United Airlines
Deal found 21/4£867

Find flight deals from Panama City to Manchester

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Manchester (MAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 22 April 2026.

Round-trip from

£778

One-way from

£448

Popular in

September

Cheapest in

July

Average price

£929
4/6-11/6
  • 4/6-11/6
  • 3 total stops
  • 39h 15m total
  • Panama City to Manchester
Search Deals
28/4
  • 28/4
  • 2 total stops
  • 31h 25m total
  • Panama City to Manchester
Search Deals
Highest demand for flights based on searches. 9% potential increase in price (£80 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 7% potential price decrease (£58 potential savings vs. average return price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Panama City to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 22 April 2026.
Use the filters below to find and compare flights from Panama City to Manchester that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Fri 18/9

15:30-06:30

3 stops33h 00m

Manchester

Mon 21/9

06:05-19:31

2 stops19h 26m

£791

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Fri 22/5

21:30-11:30

1 stop32h 00m

Manchester

Fri 29/5

18:15-18:40

2 stops30h 25m

£867

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Mon 8/6

09:45-06:30

2 stops38h 45m

Manchester

Fri 12/6

09:00-04:04

2 stops25h 04m

£867

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Sun 31/5

09:45-10:25

2 stops18h 40m

Manchester

Sun 14/6

09:00-04:04

2 stops25h 04m

£878

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Thu 4/6

20:25-21:50

2 stops19h 25m

Manchester

Thu 11/6

14:25-18:40

2 stops34h 15m

£884

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Sat 5/9

09:45-17:20

2 stops25h 35m

Manchester

Wed 9/9

09:00-19:31

2 stops40h 31m

£892
Fastest return journey

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Wed 20/5

09:45-10:25

2 stops18h 40m

Manchester

Tue 2/6

06:05-19:31

2 stops19h 26m

£893
Cheapest one-way

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Thu 28/5

20:10-09:35

1 stop31h 25m

£537
Fastest single journey

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Thu 28/5

09:45-10:25

2 stops18h 40m

£538

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Tue 18/8

09:45-10:25

2 stops18h 40m

£539

Flights are sorted by cheapest return flights first.

Deals found on 21/4

Showing 1-10 of 13 resultsSorted by cheapest first
1
2

Best time to book a flight from Panama City to Manchester

Have a flexible travel schedule? Discover the best time to fly to Manchester from Panama City with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Manchester. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama City to Manchester?

    United Airlines can get you from Panama City to Manchester in just under 33h. Your travel time can differ by up to . There are 5182 mi between Panama City and Manchester.

  • Can I find deals for flights from Panama City to Manchester that include hotel bookings?

    Yes. In addition to deals on Panama City to Manchester flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Manchester?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Manchester.

  • Can I find deals for business class flights from Panama City to Manchester?

    Yes. Cheapflights offers flight deals from Panama City to Manchester by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Travelling to a place near Manchester?

Book flights to Manchester if you plan to visit one of these locations
Windermere
Bradford
Lincoln
Llandudno
Derby
Harrogate
Southport
Stoke-on-Trent
Otley
Warrington
Lancaster
Telford
Salford
Huddersfield
Shrewsbury
Preston
Wakefield
Bolton
Wilmslow
Macclesfield

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Panama City to Manchester

See prices for flight routes from nearby airports that may be better suited for you.
Panama City to Heathrow flights
Panama City to Gatwick flights
Panama City to Stansted flights
Panama City to Edinburgh flights
Panama City to Birmingham flights
David to Manchester flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Panama City to Manchester?

When you search for this flight from Panama City to Manchester, Cheapflights searches on 900+ travel sites to save you time finding great flight deals online. Additionally, we offer filter features so you can choose a preferred cabin class or airline, see different price ranges, and much more so you can book the flight for you.

Why should you use Cheapflights to find cheap flight tickets from Panama City to Manchester?

Cheapflights helps you find that perfect flight to Manchester from Panama City by searching from hundreds of airlines and agencies you know and love. We are also free to use, in case you were wondering!

Can Cheapflights find flights from Panama City to Manchester with no change fees?

Yes! Cheapflights helps users easily find flights from Panama City to Manchester with no change fees.

Can Cheapflights notify me if prices for flights from Panama City to Manchester become cheaper?

Yes! Start tracking prices for Panama City to Manchester flights today and get alerted whenever prices for these flights change. To access this feature, click the bell icon next to the flight deals above, which will prompt you for a valid email address to receive your alerts.

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