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Cheap flights from Manchester to Panama from £343

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 20/8. Fares are subject to change and may not be available on all flights or dates of travel.
MAN — PTY
25 May — 1 Jun1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Manchester to Panama

Enter your travel dates to find the best prices.

Cheapest flights from Manchester to Panama
Explore the most affordable flight options available from Manchester to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 25 April 2026.

Mon 28/1211:50
MAN
-
PTY
2 stops46h 20m
United Airlines
Thu 14/110:00
PTY
-
MAN
2 stops19h 20m
United Airlines
Deal found 25/4£692
Mon 16/1111:50
MAN
-
PTY
2 stops31h 55m
United Airlines
Mon 23/1110:00
PTY
-
MAN
2 stops19h 20m
United Airlines
Deal found 20/4£693
Thu 21/505:55
MAN
-
PTY
1 stop16h 55m
KLM
Sun 7/618:50
PTY
-
MAN
1 stop19h 15m
KLM
Deal found 22/4£694
Sat 16/506:05
MAN
-
PTY
2 stops27h 59m
United Airlines
Sun 7/622:55
PTY
-
MAN
2 stops29h 30m
United Airlines
Deal found 24/4£700
Wed 10/609:30
MAN
-
PTY
1 stop16h 30m
British Airways
Sun 14/613:14
PTY
-
MAN
2 stops40h 16m
British Airways
Deal found 23/4£719
Wed 20/506:05
MAN
-
PTY
2 stops19h 26m
United Airlines
Thu 4/609:45
PTY
-
MAN
2 stops18h 40m
United Airlines
Deal found 22/4£726
Fri 11/1209:30
MAN
-
PTY
2 stops48h 40m
United Airlines
Sun 10/116:41
PTY
-
MAN
2 stops35h 19m
United Airlines
Deal found 25/4£734
Sat 16/511:00
MAN
-
PTY
1 stop35h 50m
KLM
Sun 7/618:50
PTY
-
MAN
1 stop33h 20m
KLM
Deal found 24/4£739
Wed 20/506:35
MAN
-
PTY
1 stop18h 05m
Multiple Airlines
Thu 4/611:25
PTY
-
MAN
2 stops29h 20m
Multiple Airlines
Deal found 22/4£742
Fri 12/605:55
MAN
-
PTY
1 stop16h 55m
KLM
Thu 25/618:50
PTY
-
MAN
1 stop19h 15m
KLM
Deal found 23/4£743

Find flight deals from Manchester to Panama

Keep the following information in mind while searching for Manchester to Panama flight deals. Data was last updated 25 April 2026.

Round-trip from

£694

One-way from

£343

Popular in

December

Cheapest in

September

Average price

£772
KLM
  • KLM
  • 21/5-7/6
  • 2 total stops
  • 36h 10m total
  • Manchester to Panama
Search Deals
20/8
  • 20/8
  • 3 total stops
  • 45h 45m total
  • Manchester to Panama
Search Deals
Highest demand for flights based on searches. 3% potential increase in price (£22 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease (£8 potential savings vs. average return price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Manchester to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 25 April 2026.
Use the filters below to find and compare flights from Manchester to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight
Fastest return journey

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Wed 10/6

09:30-20:00

1 stop16h 30m

Panama City Tocumen Intl

Sun 14/6

13:14-11:30

2 stops40h 16m

£719

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Sun 5/7

23:30-20:25

1 stop26h 55m

Panama City Tocumen Intl

Sun 12/7

20:05-12:05

1 stop34h 00m

£760

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Sat 6/6

06:05-19:31

2 stops19h 26m

Panama City Tocumen Intl

Sat 13/6

15:30-17:20

2 stops43h 50m

£776

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Sat 6/6

23:30-18:25

2 stops24h 55m

Panama City Tocumen Intl

Sat 13/6

22:20-16:25

1 stop36h 05m

£806

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Thu 4/6

05:55-06:13

2 stops30h 18m

Panama City Tocumen Intl

Thu 11/6

12:56-06:30

2 stops59h 34m

£811
Cheapest one-way

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Fri 21/8

20:25-14:15

3 stops47h 50m

£352

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Wed 19/8

18:45-08:06

2 stops43h 21m

£465
Fastest single journey

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Thu 20/8

07:05-18:40

1 stop17h 35m

£539

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Tue 28/7

07:30-17:00

3 stops39h 30m

£595

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Mon 27/7

18:10-20:25

2 stops56h 15m

£614

Flights are sorted by cheapest return flights first.

Deals found on 24/4

Showing 1-10 of 11 resultsSorted by cheapest first
1
2

Best time to book a flight from Manchester to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Manchester with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to Panama

How far ahead should I book a flight from Manchester to Panama?

Booking 83 days in advance of your planned departure date is, on average, the best time to get cheap flights from Manchester to Panama. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Manchester to Panama?

Currently, February is the cheapest month in which you can book a flight from Manchester to Panama (average of £552). Flying from Manchester to Panama in December is currently the most expensive (average of £691). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated 25 April 2026.
Get a feel of what it's like to fly with KLM,Air France, andTurkish Airlines from Manchester to Panama by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7.8
Good
1,508 reviews
Check prices

Boarding

7.8

Crew

8.4

Overall

7.8

Food

7.3

Comfort

7.7

Entertainment

7.1

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
KLM
7.8
Good
1,508 reviews
KLM
7.8
Good
1,508 reviews
Check prices

Boarding

7.8

Crew

8.4

Overall

7.8

Food

7.3

Comfort

7.7

Entertainment

7.1

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
Air France
7.4
Good
1,579 reviews
KLM
7.8
Good
1,508 reviews
Check prices

Boarding

7.8

Crew

8.4

Overall

7.8

Food

7.3

Comfort

7.7

Entertainment

7.1

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
Turkish Airlines
7.4
Good
4,330 reviews
KLM
7.8
Good
1,508 reviews
Check prices

Boarding

7.8

Crew

8.4

Overall

7.8

Food

7.3

Comfort

7.7

Entertainment

7.1

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
United Airlines
7.4
Good
9,657 reviews
KLM
7.8
Good
1,508 reviews
Check prices

Boarding

7.8

Crew

8.4

Overall

7.8

Food

7.3

Comfort

7.7

Entertainment

7.1

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
Lufthansa
6.8
Okay
7,952 reviews
KLM
7.8
Good
1,508 reviews
Check prices

Boarding

7.8

Crew

8.4

Overall

7.8

Food

7.3

Comfort

7.7

Entertainment

7.1

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas

Related info for your journey

Find useful and relevant information for your journey from Manchester to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Manchester to Panama?

    Manchester (MAN) is the airport you will fly out of if you book a flight from Manchester to Panama. It is only a 8.9 mi journey to Manchester (MAN) from Manchester’s city center.

  • How long is the flight from Manchester to Panama?

    British Airways can get you from Manchester to Panama in just under 16h 30m. Your travel time can differ by up to . Airlines will cover a distance of 5182 mi.

  • Can I find deals for flights from Manchester to Panama that include hotel bookings?

    Yes. In addition to deals on Manchester to Panama flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Manchester to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to Panama.

  • Can I find deals for business class flights from Manchester to Panama?

    Yes. Cheapflights offers flight deals from Manchester to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester to Panama?

    Currently, February is the cheapest month in which you can book a flight from Manchester to Panama (average of £552). Flying from Manchester to Panama in December is currently the most expensive (average of £691). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Manchester to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Manchester to Panama City flights
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London City to Liberia flights
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Newcastle upon Tyne to Panama City flights
Edinburgh to Panama City flights
Edinburgh to Guatemala City flights
Birmingham to San Salvador flights
Newcastle upon Tyne to San José flights
Manchester to San Salvador flights
Birmingham to San Pedro Sula flights
Manchester to San Pedro Sula flights
Manchester to Guatemala City flights
Leeds to Panama City flights
Edinburgh to Philip S.W.Goldson flights
Manchester to Managua flights
Leeds to San José flights

Top 5 airlines flying from Manchester to Panama

Discover the top 5 airlines that operate flights from Manchester to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 25 April 2026.
AirlineCheapestAverageFlexibilityOn-time
Air FranceCheapest£559Average£708FlexibilityNo cancel feeOn-time77%
Search Air France flights
United AirlinesCheapest£601Average£690FlexibilityNo cancel feeOn-time69%
Search United Airlines flights
LufthansaCheapest£603Average£671FlexibilityNo cancel feeOn-time76%
Search Lufthansa flights
KLMCheapest£604Average£809FlexibilityNo cancel feeOn-time75%
Search KLM flights
Turkish AirlinesCheapest£647Average£715FlexibilityNo cancel feeOn-time77%
Search Turkish Airlines flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Manchester to Panama?

900+ travel sites are searched through when a user searches for a flight using Cheapflights. From the search interface, users can use filters to choose airlines, airports, flight times, cabin classes and more to their preference. Book your flight to Panama from Manchester today with Cheapflights!

Why should you use Cheapflights to find cheap flight tickets from Manchester to Panama?

Cheapflights helps you find that perfect flight to Panama from Manchester by searching from hundreds of airlines and agencies you know and love. We are also free to use, in case you were wondering!

Can Cheapflights find flights from Manchester to Panama with no change fees?

Cheapflights does show flights with no change fees to all users. To see these options for flights from Manchester to Panama, users can toggle the no change fees filter when performing a flight search.

Can Cheapflights notify me if prices for flights from Manchester to Panama become cheaper?

Yes, Cheapflights offers price alerts on Manchester to Panama flights so you can book your travel at the perfect time. Price Alerts can be enabled by clicking the bell icon next to the flight deals above and providing your email address where you want to receive the alerts.

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